Page last updated: 2024-09-02

hydroxybenzylpindolol and pindolol

hydroxybenzylpindolol has been researched along with pindolol in 27 studies

Compound Research Comparison

Studies
(hydroxybenzylpindolol)
Trials
(hydroxybenzylpindolol)
Recent Studies (post-2010)
(hydroxybenzylpindolol)
Studies
(pindolol)
Trials
(pindolol)
Recent Studies (post-2010) (pindolol)
30103,71866292

Protein Interaction Comparison

ProteinTaxonomyhydroxybenzylpindolol (IC50)pindolol (IC50)
Beta-2 adrenergic receptorHomo sapiens (human)0.0005
Beta-1 adrenergic receptorHomo sapiens (human)0.0009
Beta-3 adrenergic receptorHomo sapiens (human)0.088
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.048
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.048

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199026 (96.30)18.7374
1990's1 (3.70)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harden, TK; Perkins, JP; Su, YF1
Petcher, TJ; Weber, HP1
Elks, ML; Manganiello, VC1
Hatjis, CG2
Steiner, E; Tawara, K; von Bahr, C1
Prásek, J; Prikryl, P; Rysánek, K; Vondrácek, V1
Le Fur, G; Paillard, JJ; Rougeot, C; Uzan, A1
Canton, T; Guérémy, C; Hardy, JC; Le Fur, G; Malgouris, C; Paillard, JJ; Uzan, A1
Harden, TK; McCarthy, KD1
Eckelman, WC; Francis, B; Gibson, RE; Grissom, MP; Reba, RC1
Ball, AJ; Basran, GS; Hanson, JM; Morley, J; Turner-Warwick, M1
Ludford, JM; Talamo, BR1
Haber, E; Homcy, CJ; Rockson, SG1
Adams, K; Darovec-Beckerman, C; Manton, MA; Whitsett, JA1
Bürgisser, E; De Lean, A; Hancock, AA; Lefkowitz, RJ1
Kempner, E; Lad, PM; Nielsen, TB; Preston, MS; Rodbell, M; Schlegel, W1
Bürgisser, E; DeLean, A; Lefkowitz, RJ1
Greenberg, ML; Malbon, CC1
Brink, C; Douglas, JS; Duncan, PG1
Atlas, D; Steer, ML1
Moore, JJ; Whitsett, JA1
Nauman, J; Szymański, PT1
Szymański, PT1
Chader, GJ; Koh, SW1
Alvan, G; Strandvik, B; Tawara, K1
Abou-Sayf, FK; Carlsson, C; Carney, E; Cutler, S; Fuse, A; Gallagher, ET; Ogawa, R; Saito, T; Takanashi, M; Yamada, K1

Trials

1 trial(s) available for hydroxybenzylpindolol and pindolol

ArticleYear
The effect of methylprednisolone on myocardial beta-adrenergic receptors and cardiovascular function in shock patients.
    Shock (Augusta, Ga.), 1996, Volume: 5, Issue:4

    Topics: Adult; Blood Pressure; Catecholamines; Female; Heart; Heart Rate; Humans; Male; Methylprednisolone; Middle Aged; Myocardium; Pindolol; Receptors, Adrenergic, beta; Shock; Vascular Resistance

1996

Other Studies

26 other study(ies) available for hydroxybenzylpindolol and pindolol

ArticleYear
Catecholamine-induced desensitization involves an uncoupling of beta-adrenergic receptors and adenylate cyclase.
    Journal of cyclic nucleotide research, 1979, Volume: 5, Issue:2

    Topics: Adenylyl Cyclases; Astrocytoma; Benzyl Alcohols; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Guanosine Triphosphate; Isoproterenol; Membranes; Pindolol; Protein Binding; Receptors, Adrenergic; Receptors, Adrenergic, beta

1979
The crystal and molecular structure of hydroxybenzylpindolol.
    Helvetica chimica acta, 1977, Jun-01, Volume: 60, Issue:4

    Topics: Benzyl Alcohols; Chemical Phenomena; Chemistry; Crystallization; Molecular Conformation; Pindolol

1977
Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes.
    Endocrinology, 1985, Volume: 117, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue; Animals; Cattle; Cell Differentiation; Cell Line; Cyclic AMP; Hyperthyroidism; Hypothyroidism; Insulin; Isoproterenol; Lipolysis; Mice; Pindolol; Receptors, Adrenergic, beta; Triiodothyronine

1985
beta-Adrenergic-receptor and adenylate cyclase properties in pregnant and nonpregnant guinea pig myometrium.
    American journal of obstetrics and gynecology, 1985, Apr-01, Volume: 151, Issue:7

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding Sites; Binding, Competitive; Female; Guinea Pigs; In Vitro Techniques; Myometrium; Pindolol; Postpartum Period; Pregnancy; Pregnancy, Animal; Receptors, Adrenergic, beta; Time Factors

1985
The effect of propranolol on exercise induced tachycardia is determined by plasma concentration and the density of adrenergic receptors on leukocytes.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:6

    Topics: Adult; Heart Rate; Humans; Leukocytes; Male; Neutrophils; Physical Exertion; Pindolol; Propranolol; Receptors, Adrenergic

1987
Beta-adrenergic receptor interaction with guanosine triphosphate in fetal rabbit myocardial membranes.
    Biology of the neonate, 1984, Volume: 46, Issue:5

    Topics: Animals; Binding, Competitive; Fetus; Gestational Age; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Membranes; Myocardium; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic, beta

1984
[Determination of the binding affinity of beta-adrenergic receptors in human lymphocytes using 125I-hydroxybenzylpindolol].
    Casopis lekaru ceskych, 1984, Oct-19, Volume: 123, Issue:42

    Topics: Adolescent; Adult; beta-Endorphin; Binding, Competitive; Endorphins; Humans; Iodine Radioisotopes; Lymphocytes; Male; Pindolol; Receptors, Opioid

1984
Tissue levels and displacement of in vivo labelled beta-adrenergic receptors by FM 24, an irreversible or slowly dissociable beta-blocker.
    European journal of pharmacology, 1980, Oct-31, Volume: 67, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Benzyl Alcohols; Bridged Bicyclo Compounds; Kinetics; Mice; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta

1980
Stereospecificity of the in vitro and in vivo blockade of beta-receptors by FM 24, a slowly reversible ligand.
    Life sciences, 1981, Dec-14, Volume: 29, Issue:24

    Topics: Adrenergic beta-Antagonists; Animals; Benzyl Alcohols; Binding, Competitive; Cerebral Cortex; Dihydroalprenolol; In Vitro Techniques; Kinetics; Male; Membranes; Pindolol; Propanolamines; Propranolol; Rats; Stereoisomerism

1981
Identification of the beta adrenergic receptor subtype on astroglia purified from rat brain.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Astrocytoma; Cells, Cultured; Cerebral Cortex; Ethanolamines; Glioma; Lung; Metoprolol; Neuroglia; Pindolol; Practolol; Propanolamines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta

1982
The use of tritium labeled compounds to develop gamma-emitting receptor-binding radiotracers.
    International journal of nuclear medicine and biology, 1982, Volume: 9, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Dihydroalprenolol; Dioxanes; Dogs; Guinea Pigs; Heart; Humans; Male; N-Methylscopolamine; Parasympatholytics; Pindolol; Prazosin; Propanolamines; Quinuclidinyl Benzilate; Rabbits; Radionuclide Imaging; Rats; Scopolamine Derivatives; Tritium

1982
Circulating beta-adrenoceptor blocking factors in asthma.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Binding Sites; Eosinophilia; Humans; Lung; Pindolol; Theophylline

1984
beta-Adrenergic and muscarinic receptors in developing rat parotid glands. Selective effect of neonatal sympathetic denervation.
    The Journal of biological chemistry, 1980, May-25, Volume: 255, Issue:10

    Topics: Adenylyl Cyclases; Amylases; Animals; Animals, Newborn; Benzyl Alcohols; Binding, Competitive; Choline O-Acetyltransferase; Denervation; Isoproterenol; Kinetics; Norepinephrine; Parotid Gland; Pindolol; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Muscarinic

1980
Anti-alprenolol antibodies in the rabbit. A new probe for the study of beta-adrenergic receptor interaction.
    Circulation research, 1980, Volume: 46, Issue:6

    Topics: Alprenolol; Animals; Antibodies; Antibody Affinity; Benzyl Alcohols; Binding Sites, Antibody; Binding, Competitive; Chemical Fractionation; Immune Sera; Immunosorbent Techniques; Pindolol; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta

1980
II. Beta-adrenergic receptors and catecholamine sensitive adenylate cyclase in the developing rat lung.
    Life sciences, 1981, Jan-26, Volume: 28, Issue:4

    Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Catecholamines; Cell Membrane; Dihydroalprenolol; Enzyme Activation; Epinephrine; Female; Isoproterenol; Lung; Male; Norepinephrine; Pindolol; Pregnancy; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta

1981
Anomalous equilibrium binding properties of high-affinity racemic radioligands.
    Molecular pharmacology, 1981, Volume: 19, Issue:2

    Topics: Animals; Benzyl Alcohols; Carbazoles; Erythrocyte Membrane; In Vitro Techniques; Models, Biological; Pindolol; Propanolamines; Radioligand Assay; Ranidae; Receptors, Adrenergic; Receptors, Adrenergic, beta

1981
Structure of the turkey erythrocyte adenylate cyclase system.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:2

    Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Erythrocytes; Fluorides; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Molecular Weight; Pindolol; Protein Binding; Receptors, Adrenergic, beta; Turkeys

1981
Alternative explanation for the apparent "two-step" binding kinetics of high-affinity racemic antagonist radioligands.
    Molecular pharmacology, 1981, Volume: 19, Issue:3

    Topics: Animals; Benzyl Alcohols; Carbazoles; Computers; Erythrocyte Membrane; Kinetics; Models, Chemical; Pindolol; Propanolamines; Ranidae; Receptors, Adrenergic; Receptors, Adrenergic, beta; Stereoisomerism

1981
3,3',5-triiodothyronine administration in vivo modulates the hormone-sensitive adenylate cyclase system of rat hepatocytes.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:2

    Topics: Adenylyl Cyclases; Animals; Benzyl Alcohols; Cholera Toxin; Cyclic AMP; Epinephrine; Female; Glucagon; Guanosine Triphosphate; Hormones; Hyperthyroidism; Isoproterenol; Liver; Pindolol; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Triiodothyronine; Triiodothyronine, Reverse

1982
Beta-receptors during aging in respiratory tissues.
    European journal of pharmacology, 1982, Feb-19, Volume: 78, Issue:1

    Topics: Aging; Animals; Benzyl Alcohols; Bronchi; Female; Guinea Pigs; Histamine; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Pindolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Respiratory System; Trachea

1982
Demonstration of human platelet beta-adrenergic receptors using 125I-labeled cyanopindolol and 125I-labeled hydroxybenzylpindolol.
    Biochimica et biophysica acta, 1982, Apr-07, Volume: 686, Issue:2

    Topics: Blood Platelets; Cell Membrane; Humans; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Pindolol; Receptors, Adrenergic; Receptors, Adrenergic, beta

1982
The beta-adrenergic receptor in human placenta: receptor subtype analysis (beta 1 and beta 2) and partial characterization of the solubilized receptor.
    Placenta. Supplement, 1981, Volume: 3

    Topics: Chromatography, Gel; Dihydroalprenolol; Female; Humans; Iodine Radioisotopes; Pindolol; Placenta; Pregnancy; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, beta; Solubility

1981
[Beta adrenergic receptors in the rat myocardium. 1. Optimal conditions for interaction of J-125-labeled hydroxybenzylpindolol with beta adrenergic receptors].
    Endokrynologia Polska, 1983, Volume: 34, Issue:4

    Topics: Animals; Cattle; Cell Membrane; In Vitro Techniques; Male; Myocardium; Pindolol; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1983
[Beta adrenergic receptors in the rat myocardium. II. Determination of the kinetic parameters of interaction of J-125-labeled hydroxybenzylpindolol with beta adrenergic receptors].
    Endokrynologia Polska, 1983, Volume: 34, Issue:5

    Topics: Animals; Binding Sites; Cell Membrane; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Male; Myocardium; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1983
Retinal pigment epithelium in culture demonstrates a distinct beta-adrenergic receptor.
    Experimental eye research, 1984, Volume: 38, Issue:1

    Topics: Animals; Cells, Cultured; Chick Embryo; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Isoproterenol; Norepinephrine; Pigment Epithelium of Eye; Pindolol; Receptors, Adrenergic, beta

1984
Imbalance between alpha- and beta-adrenoceptor binding sites in marker cells in cystic fibrosis.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 43, Issue:3

    Topics: Blood Platelets; Cystic Fibrosis; Humans; In Vitro Techniques; Pindolol; Proteins; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine

1984