Page last updated: 2024-09-03

hydroxybenzylisoproterenol and isoproterenol

hydroxybenzylisoproterenol has been researched along with isoproterenol in 26 studies

Compound Research Comparison

Studies
(hydroxybenzylisoproterenol)
Trials
(hydroxybenzylisoproterenol)
Recent Studies (post-2010)
(hydroxybenzylisoproterenol)
Studies
(isoproterenol)
Trials
(isoproterenol)
Recent Studies (post-2010) (isoproterenol)
270130,7808032,640

Protein Interaction Comparison

ProteinTaxonomyhydroxybenzylisoproterenol (IC50)isoproterenol (IC50)
Beta-2 adrenergic receptorHomo sapiens (human)0.246
Beta-1 adrenergic receptorHomo sapiens (human)0.333
Beta-2 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)1.77
Beta-1 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-3 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-2 adrenergic receptorCanis lupus familiaris (dog)0.6667

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199025 (96.15)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eimerl, S; Goodman, M; Khan, M; Lok, S; Melmon, K; Schramm, M1
Benghan-Eyene, Y; Legrand, C; Maltier, JP1
Crooke, ST; Stadel, JM1
Abramson, SN; Barrett, DA; Harden, TK; Hughes, AR; Martin, MW; Molinoff, PB; Neve, KA1
Legrand, C; Maltier, JP1
Abramson, SN; Hoyer, D; Molinoff, PB; Reynolds, EE1
Baker, SP; Muther, TF; Nelson, CA; Pitha, J1
Delavier-Klutchko, C; Durieu-Trautmann, O; Hoebeke, J; Strosberg, AD1
Abramson, SN; Molinoff, PB; Shorr, RG1
Heidenreich, KA; Molinoff, PB; Weiland, GA2
Dietz, J; Kaiser, G; Palm, D; Reinhardt, M; Wellstein, A; Wiemer, G1
Besch, HR; Jones, LR; Manalan, AS; Watanabe, AM1
Palm, D; Wellstein, A; Wiemer, G1
Agli, B; Giudicelli, Y; Lacasa, D1
Lefkowitz, RJ; Stadel, JM1
Brockmeier, D; Palm, D; von Hattingberg, HM; Wellstein, A; Wiemer, G1
Abramson, SN; Molinoff, PB1
Lefkowitz, RJ; Voeikov, VL1
De Lean, A; Lefkowitz, RJ; Stadel, JM1
Malbon, CC1
Caron, MG; Heald, SL; Jeffs, PW; Lefkowitz, RJ; Pitha, J; Shorr, RG; Zjawiony, J1
De Lean, A; Lefkowitz, RJ; Rouleau, D1
Krzanowski, JJ; Szentivanyi, A1
Gordon, MA; Johnson, DL1
Enos, MD; Garcia, KC; Kobilka, BK; Kruse, AC; Manglik, A; Ring, AM; Weis, WI1

Reviews

2 review(s) available for hydroxybenzylisoproterenol and isoproterenol

ArticleYear
Cardiac autonomic receptors. Recent concepts from radiolabeled ligand-binding studies.
    Circulation research, 1982, Volume: 50, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Columbidae; Dihydroalprenolol; Dogs; Epinephrine; Guanine Nucleotides; Guinea Pigs; Heart Conduction System; Isoproterenol; Myocardium; Pindolol; Propranolol; Rabbits; Radioligand Assay; Ranidae; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Sensory Receptor Cells

1982
Reflections on some aspects of current research in asthma.
    The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:5 Pt 1

    Topics: Animals; Asthma; Autoimmune Diseases; Dihydroalprenolol; Guinea Pigs; Humans; Hypersensitivity, Immediate; Isoproterenol; Lymphocytes; Magnetic Resonance Spectroscopy; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Drug; Tomography, Emission-Computed

1983

Other Studies

24 other study(ies) available for hydroxybenzylisoproterenol and isoproterenol

ArticleYear
The four stereoisomers of a high potency congener of isoproterenol. Biological activity and the relationship between the native and the chemically inserted asymmetric carbon.
    Biochemical pharmacology, 1987, Oct-15, Volume: 36, Issue:20

    Topics: Adenylyl Cyclases; Animals; Erythrocytes; In Vitro Techniques; Isoproterenol; Kinetics; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship; Turkeys

1987
Rat myometrial adrenergic receptors in late pregnancy.
    Biology of reproduction, 1987, Volume: 37, Issue:3

    Topics: 5'-Nucleotidase; Animals; Female; Isoproterenol; Myometrium; Nucleotidases; Prazosin; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1987
Differential effects of fluoride on adenylate cyclase activity and guanine nucleotide regulation of agonist high-affinity receptor binding.
    The Biochemical journal, 1988, Aug-15, Volume: 254, Issue:1

    Topics: Adenylyl Cyclases; Alprostadil; Animals; Anura; Cell Membrane; Cells, Cultured; Colforsin; Dihydroalprenolol; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Isoproterenol; Pindolol; Receptors, Adrenergic, beta; Sodium Fluoride; Yohimbine

1988
Interaction of beta-adrenergic receptors with the inhibitory guanine nucleotide-binding protein of adenylate cyclase in membranes prepared from cyc- S49 lymphoma cells.
    Biochemical pharmacology, 1988, Nov-15, Volume: 37, Issue:22

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; GTP-Binding Proteins; Isoproterenol; Lymphoma; Membranes; Molecular Weight; NAD; Pertussis Toxin; Pindolol; Receptors, Adrenergic, beta; Virulence Factors, Bordetella

1988
Characterization of beta-adrenoceptors in myometrium of preparturient rats.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:5

    Topics: Animals; Binding Sites; Binding, Competitive; Dihydroalprenolol; Female; In Vitro Techniques; Isoproterenol; Kinetics; Labor, Obstetric; Myometrium; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Uterine Contraction

1988
Interactions of agonists with beta-adrenergic receptors on S49 lymphoma cells.
    Advances in cyclic nucleotide and protein phosphorylation research, 1985, Volume: 19

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Albuterol; Animals; Binding, Competitive; Cell Line; Cell Membrane; Guanosine Triphosphate; Isoproterenol; Lymphoma; Mice; Pindolol; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship

1985
Differential recovery of beta adrenoreceptor antagonist and agonist high affinity binding sites in the guinea-pig lung after irreversible blockade.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Binding Sites; Dihydroalprenolol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lung; Receptors, Adrenergic, beta; Tritium

1986
Altered binding properties of beta-adrenergic receptors and lack of coupling to adenylate cyclase in P815 mastocytoma cells.
    European journal of pharmacology, 1985, Jan-22, Volume: 108, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Dihydroalprenolol; Diterpenes; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Mast-Cell Sarcoma; Mice; Mice, Inbred DBA; Neoplasm Proteins; Receptors, Adrenergic, beta; Sarcoma, Experimental; Sodium Fluoride

1985
Interactions of beta-adrenergic receptors with a membrane protein other than the stimulatory guanine nucleotide-binding protein.
    Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14

    Topics: Adenylyl Cyclases; Animals; Cell Line; GTP-Binding Proteins; Isoproterenol; Lymphoma; Membrane Proteins; Neoplasm Proteins; Pindolol; Protein Binding; Rats; Receptors, Adrenergic, beta

1987
Characterization of radiolabeled agonist binding to beta-adrenergic receptors in mammalian tissues.
    Journal of cyclic nucleotide research, 1980, Volume: 6, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Catecholamines; Cell Membrane; Erythrocyte Membrane; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lung; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes

1980
Desensitization of the beta-adrenoceptor-adenylate cyclase system of immature erythrocytes by in-vivo treatment of rats with isoprenaline.
    Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 317, Issue:4

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cyclic AMP; Dihydroalprenolol; Dose-Response Relationship, Drug; Erythrocytes; Isoproterenol; Male; Papaverine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta

1981
Beta-adrenoceptor sites in maturing red blood cells of the rat: differing development of agonist and antagonist binding.
    European journal of pharmacology, 1982, Jan-22, Volume: 77, Issue:2-3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dihydroalprenolol; Erythrocytes; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes; Time Factors

1982
Characteristics of beta-adrenergic-agonist binding to rat adipocyte membranes. Evidence that (+/-)-[3H]hydroxybenzylisoproterenol interacts selectively with the adipocyte beta-adrenergic receptors.
    Biochimica et biophysica acta, 1982, Mar-15, Volume: 715, Issue:1

    Topics: Adipose Tissue; Adrenergic beta-Agonists; Animals; Binding, Competitive; Cell Membrane; Dihydroalprenolol; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta

1982
Differential effects of cholera toxin on guanine nucleotide regulation of beta-adrenergic agonist high affinity binding and adenylate cyclase activation in frog erythrocyte membranes.
    Journal of cyclic nucleotide research, 1981, Volume: 7, Issue:6

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Binding, Competitive; Cholera Toxin; Erythrocyte Membrane; Erythrocytes; GTP-Binding Proteins; Guanine Nucleotides; Isoproterenol; Kinetics; Ranidae; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cell Surface

1981
Properties of agonist binding at the beta-adrenoceptor of the rat reticulocyte.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 321, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Dihydroalprenolol; Erythrocyte Membrane; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes; Stereoisomerism; Temperature

1982
In vitro interactions of agonists and antagonists with beta-adrenergic receptors.
    Biochemical pharmacology, 1984, Mar-15, Volume: 33, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Epinephrine; Guanosine Triphosphate; Humans; Isoproterenol; Magnesium; Models, Biological; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Sulfhydryl Reagents; Thermodynamics

1984
Effects of local anesthetics on guanyl nucleotide modulation of the catecholamine-sensitive adenylate cyclase system and on beta-adrenergic receptors.
    Biochimica et biophysica acta, 1980, May-07, Volume: 629, Issue:2

    Topics: Adenylyl Cyclases; Anesthetics, Local; Animals; Anura; Catecholamines; Dihydroalprenolol; Erythrocyte Membrane; Guanine Nucleotides; In Vitro Techniques; Isoproterenol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetracaine

1980
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.
    The Journal of biological chemistry, 1980, Aug-10, Volume: 255, Issue:15

    Topics: Adenylyl Cyclases; Alprenolol; Animals; Anura; Binding Sites; Binding, Competitive; Dihydroalprenolol; Erythrocyte Membrane; Erythrocytes; Isoproterenol; Kinetics; Mathematics; Protein Binding; Receptors, Adrenergic; Receptors, Adrenergic, beta; Turkeys

1980
Beta-adrenergic activity of (+/-)-hydroxybenzylisoproterenol in isolated rat fat cells and hepatocytes.
    Biochimica et biophysica acta, 1981, Mar-05, Volume: 673, Issue:2

    Topics: Adipose Tissue; Animals; Binding, Competitive; Cyclic AMP; Female; In Vitro Techniques; Isomerism; Isoproterenol; Kinetics; Liver; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Structure-Activity Relationship; Subcellular Fractions

1981
Isolation and characterization of the beta-adrenergic receptor of frog erythrocytes and development of potential affinity ligands.
    Advances in cyclic nucleotide research, 1981, Volume: 14

    Topics: Affinity Labels; Animals; Binding, Competitive; Dihydroalprenolol; Erythrocyte Membrane; Erythrocytes; Isoproterenol; Kinetics; Ligands; Molecular Weight; Ranidae; Receptors, Adrenergic; Receptors, Adrenergic, beta

1981
Effects of magnesium and N-ethylmaleimide on the binding of 3H-hydroxybenzylisoproterenol to beta-adrenergic receptors.
    The Journal of biological chemistry, 1982, Jan-25, Volume: 257, Issue:2

    Topics: Animals; Cell Membrane; Ethylmaleimide; Isoproterenol; Kinetics; Lung; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tritium

1982
Activation of adenylate cyclase by beta-adrenergic receptors: investigation of rate limiting steps by simultaneous assay of high affinity agonist binding and GDP release.
    Life sciences, 1983, Sep-05, Volume: 33, Issue:10

    Topics: Adenylyl Cyclases; Animals; Anura; Dose-Response Relationship, Drug; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Guanine Nucleotides; Guanosine Diphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Receptors, Adrenergic; Receptors, Adrenergic, beta

1983
Characteristics of adrenergic binding sites associated with murine lymphocytes isolated from spleen.
    Journal of immunopharmacology, 1980, Volume: 2, Issue:4

    Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Dihydroalprenolol; In Vitro Techniques; Isoproterenol; Kinetics; Lymphocytes; Mice; Receptors, Adrenergic; Spleen; Sympathomimetics

1980
Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody.
    Nature, 2013, Oct-24, Volume: 502, Issue:7472

    Topics: Adrenergic beta-2 Receptor Agonists; Benzoxazines; Binding Sites; Crystallography, X-Ray; Directed Molecular Evolution; Epinephrine; Humans; Hydrogen Bonding; Isoproterenol; Ligands; Models, Molecular; Protein Engineering; Protein Stability; Receptors, Adrenergic, beta-2; Single-Chain Antibodies; Tyrosine; Water

2013