hydroquinone and ascorbic acid

hydroquinone has been researched along with ascorbic acid in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (8.57)	18.7374
1990's	13 (37.14)	18.2507
2000's	8 (22.86)	29.6817
2010's	11 (31.43)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Carpinella, MC; Chiari, ME; Palacios, SM; Vera, DM	1
Atta, NF; Galal, A; Karagözler, AE; Mark, HB; Russell, GC; Zimmer, H	1
Furukawa, F; Hasegawa, R; Hayashi, Y; Hirose, M; Ito, N; Takahashi, M; Toyoda, K	1
Chakraborty, AK; Chakraborty, C; Chakraborty, DP; Chatterjee, A	1
Jacques, NA	1
Farhangrazi, ZS; Powers, L; Sinclair, R; Yamazaki, I	1
Abdulla, M; Chandra, O; Rehman, S	1
Amachi, T; Copeland, BR; Farhangrazi, ZS; Nakayama, T; Powers, LS; Yamazaki, I	1
Hissink, AM; Oudshoorn, MJ; Van Bladeren, PJ; Van Ommen, B	1
Balaji, KC; Laxmanan, S; Maramag, C; Menon, M; Reddy, PG	1
Barel, A; Clarys, P	1
Ozawa, T; Shimazu, Y; Takai, M; Ueda, J	1
Gal-Or, S; Jonas, A; Katzir, E; Neeman, I; Nimni, ME; Perelman, N; Rosenblat, G; Sorgente, N	1
Sakurai, I; Satoh, I	1
Draelos, ZD	1
Rogozhin, VV; Verkhoturov, VV	1
Aver'yanov, AA; Lapikova, VP; Novodarova, GN; Vol'pin, ME	1
Does, MD; Fong, PM; Gore, JC; Keil, DC	1
Aiba, E; Aoyama, T; Harii, K; Iga, T; Matsumoto, D; Mitoma, Y; Momosawa, A; Sato, K; Yoshimura, K	1
Fujita, T; Kamiyama, F; Kita, T; Kurimoto, Y; Matsubayashi, T; Nakamura, T; Nishiguchi, K; Okumura, K; Sakaeda, T; Yamamoto, A	1
LEGRAND, G; LEHONGRE, G; NEUMANN, J	1
Guevara, IL; Pandya, AG	1
Castanedo-Cazares, JP; Espinal-Perez, LE; Moncada, B	1
Görner, H	1
Ertl, P; Mann, TS; Mikkelsen, SR; O'Hagan, L; Sparkes, DI	1
Chakraborty, M; Das, S; Mandal, PC; Mukhopadhyay, S; Singh, NJ	1
Bruce, S; Watson, J	1
Kauvar, AN	1
Chervet, JP; Erb, R; Oberacher, H; Plattner, S	1
Jirimali, HD; Lee, JM; Nagarale, RK; Saravanakumar, D; Shin, W	1
Baker, R; Bell, M; Singh, SK; Tobin, DJ; Wibawa, JI	1
Apak, R; Bakır, T; Imer, F; Sönmezoğlu, I	1
García-Cánovas, F; García-Molina, Mdel M; García-Ruiz, PA; Martinez, JR; Martinez-Ortiz, F; Muñoz Muñoz, JL; Rodriguez-López, JN	1
Andersen, RM; Maibach, HI; Saxena, S	1

Reviews

2 review(s) available for hydroquinone and ascorbic acid

Article	Year
Topical agents used in association with cosmetic surgery. Seminars in cutaneous medicine and surgery, 1999, Volume: 18, Issue:2 Topics: Administration, Topical; Adolescent; Adult; Aged; Ascorbic Acid; Carotenoids; Chemexfoliation; Dicarboxylic Acids; Female; Humans; Hydroquinones; Hydroxy Acids; Keratolytic Agents; Male; Middle Aged; Postoperative Care; Preoperative Care; Retinoids; Salicylates; Skin Aging; Skin Care; Skin Pigmentation; Sunscreening Agents; Surgery, Plastic; Vitamin A; Vitamin E	1999
Pitfalls in clinical trials reveal need for well tolerated, more effective depigmenting agents. The Journal of dermatological treatment, 2015, Volume: 26, Issue:5 Topics: Ascorbic Acid; Clinical Trials as Topic; Dicarboxylic Acids; Double-Blind Method; Humans; Hydroquinones; Niacinamide; Patient Safety; Research Design; Skin Lightening Preparations; Skin Pigmentation; Vitamin A	2015

Article

Year

Topical agents used in association with cosmetic surgery.

Seminars in cutaneous medicine and surgery, 1999, Volume: 18, Issue:2

Topics: Administration, Topical; Adolescent; Adult; Aged; Ascorbic Acid; Carotenoids; Chemexfoliation; Dicarboxylic Acids; Female; Humans; Hydroquinones; Hydroxy Acids; Keratolytic Agents; Male; Middle Aged; Postoperative Care; Preoperative Care; Retinoids; Salicylates; Skin Aging; Skin Care; Skin Pigmentation; Sunscreening Agents; Surgery, Plastic; Vitamin A; Vitamin E

1999

Pitfalls in clinical trials reveal need for well tolerated, more effective depigmenting agents.

The Journal of dermatological treatment, 2015, Volume: 26, Issue:5

Topics: Ascorbic Acid; Clinical Trials as Topic; Dicarboxylic Acids; Double-Blind Method; Humans; Hydroquinones; Niacinamide; Patient Safety; Research Design; Skin Lightening Preparations; Skin Pigmentation; Vitamin A

2015

Trials

5 trial(s) available for hydroquinone and ascorbic acid

Article	Year
Clinical trial of bleaching treatment with 10% all-trans retinol gel. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2003, Volume: 29, Issue:2 Topics: Adult; Aged; Ascorbic Acid; Dermatitis, Irritant; Drug Therapy, Combination; Erythema; Female; Gels; Humans; Hydroquinones; Hyperpigmentation; Lactic Acid; Middle Aged; Treatment Outcome; Vitamin A	2003
Safety and efficacy of 4% hydroquinone combined with 10% glycolic acid, antioxidants, and sunscreen in the treatment of melasma. International journal of dermatology, 2003, Volume: 42, Issue:12 Topics: Administration, Cutaneous; Adult; Ascorbic Acid; Drug Therapy, Combination; Female; Glycolates; Humans; Hydroquinones; Keratolytic Agents; Melanosis; Severity of Illness Index; Sunscreening Agents; Treatment Outcome; Vitamin E	2003
A double-blind randomized trial of 5% ascorbic acid vs. 4% hydroquinone in melasma. International journal of dermatology, 2004, Volume: 43, Issue:8 Topics: Administration, Topical; Adult; Ascorbic Acid; Dermatologic Agents; Double-Blind Method; Female; Humans; Hydroquinones; Melanosis; Treatment Outcome	2004
Evaluation of a prescription strength 4% hydroquinone/10% L-ascorbic acid treatment system for normal to oily skin. Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:12 Topics: Adult; Ascorbic Acid; Dermatologic Agents; Drug Combinations; Female; Follow-Up Studies; Humans; Hydroquinones; Hyperpigmentation; Patient Satisfaction; Sebum; Severity of Illness Index; Skin Aging; Skin Care; Treatment Outcome	2011
Successful treatment of melasma using a combination of microdermabrasion and Q-switched Nd:YAG lasers. Lasers in surgery and medicine, 2012, Volume: 44, Issue:2 Topics: Adult; Antioxidants; Ascorbic Acid; Combined Modality Therapy; Dermabrasion; Female; Follow-Up Studies; Humans; Hydroquinones; Keratolytic Agents; Lasers; Lasers, Solid-State; Melanosis; Middle Aged; Single-Blind Method; Sunscreening Agents; Treatment Outcome; Tretinoin	2012

Other Studies

28 other study(ies) available for hydroquinone and ascorbic acid

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Tyrosinase inhibitory activity of a 6-isoprenoid-substituted flavanone isolated from Dalea elegans. Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11 Topics: Agaricales; Binding Sites; Computer Simulation; Enzyme Inhibitors; Fabaceae; Flavanones; Kinetics; Monophenol Monooxygenase; Terpenes	2011
Electrochemistry and detection of some organic and biological molecules at conducting poly(3-methylthiophene) electrodes. Biosensors & bioelectronics, 1991, Volume: 6, Issue:4 Topics: Acetaminophen; Aminophenols; Ascorbic Acid; Biosensing Techniques; Catechols; Dopamine; Electrochemistry; Epinephrine; Hydroquinones; Iron; NAD; Polymers; Thiophenes	1991
Inhibitory effects of antioxidants on N-bis(2-hydroxypropyl)nitrosamine-induced lung carcinogenesis in rats. Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:9 Topics: Adenoma; Animals; Antioxidants; Ascorbic Acid; Body Weight; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinoma; Catechols; Ethoxyquin; Hydroquinones; Kidney Neoplasms; Lung Neoplasms; Male; Nitrosamines; Organ Size; Rats; Rats, Inbred F344; Resorcinols; Thyroid Neoplasms; Urinary Bladder Neoplasms; Vitamin E	1990
Inverse relationship between melanogenesis and endogenous hydroquinone. Experientia, 1984, Aug-15, Volume: 40, Issue:8 Topics: Animals; Ascorbic Acid; Bufonidae; Ficusin; Hydroquinones; Liver; Male; Melanins; Muridae; Rats; Rats, Inbred Strains; Skin	1984
Studies on cyclopropane fatty acid synthesis. Correlation between the state of reduction of respiratory components and the accumulation of methylene hexadecanoic acid by Pseudomonas denitrificans. Biochimica et biophysica acta, 1981, Aug-24, Volume: 665, Issue:2 Topics: Ascorbic Acid; Cyclopropanes; Fatty Acids; Hydroquinones; Methionine; Methyltransferases; NAD; Oxidation-Reduction; Oxygen Consumption; Pseudomonas	1981
Formation of a porphyrin pi-cation radical in the fluoride complex of horseradish peroxidase. Biochemistry, 1995, Nov-21, Volume: 34, Issue:46 Topics: Ascorbic Acid; Fluorides; Free Radicals; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroquinones; Iridium; Oxidation-Reduction; Porphyrins; Potassium Cyanide; Sodium Fluoride; Spectrophotometry	1995
Evaluation of malondialdehyde as an index of lead damage in rat brain homogenates. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 1995, Volume: 8, Issue:4 Topics: Animals; Ascorbic Acid; Brain; Drug Interactions; Hydroquinones; Lead; Lipid Peroxidation; Malondialdehyde; Rats; Vitamin E	1995
Oxidation-reduction properties of compounds I and II of Arthromyces ramosus peroxidase. Biochemistry, 1994, May-10, Volume: 33, Issue:18 Topics: Ascorbic Acid; Catalysis; Electron Spin Resonance Spectroscopy; Enzyme Stability; Hydrogen-Ion Concentration; Hydroquinones; Mitosporic Fungi; Oxidation-Reduction; Peroxidase	1994
Species and strain differences in the hepatic cytochrome P450-mediated biotransformation of 1,4-dichlorobenzene. Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1 Topics: Animals; Ascorbic Acid; Binding, Competitive; Biotransformation; Carcinogens; Chlorobenzenes; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Glutathione; Humans; Hydroquinones; Insecticides; Isotope Labeling; Male; Mice; Microsomes, Liver; Mutagens; Phenobarbital; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity	1997
Effect of vitamin C on prostate cancer cells in vitro: effect on cell number, viability, and DNA synthesis. The Prostate, 1997, Aug-01, Volume: 32, Issue:3 Topics: Androgens; Antineoplastic Agents; Ascorbic Acid; Azides; Cell Count; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Free Radicals; Humans; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; In Vitro Techniques; Male; Prostatic Neoplasms; Sodium Azide; Superoxide Dismutase; Thymidine; Tritium; Tumor Cells, Cultured	1997
Efficacy of topical treatment of pigmentation skin disorders with plant hydroquinone glucosides as assessed by quantitative color analysis. The Journal of dermatology, 1998, Volume: 25, Issue:6 Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Apiaceae; Ascorbic Acid; Benzoyl Peroxide; Citrus; Colorimetry; Dermatologic Agents; Drug Combinations; Female; Follow-Up Studies; Glucosides; Humans; Hydroquinones; Lentigo; Male; Melanins; Middle Aged; Oils, Volatile; Oxyquinoline; Plant Extracts; Skin Pigmentation	1998
Reactive oxygen species generated from the reaction of copper(II) complexes with biological reductants cause DNA strand scission. Archives of biochemistry and biophysics, 1998, Sep-15, Volume: 357, Issue:2 Topics: Acetylcysteine; Ascorbic Acid; Copper; DNA Damage; Electron Spin Resonance Spectroscopy; Glutathione; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; Oxidation-Reduction; Plasmids; Reactive Oxygen Species; Reducing Agents; Spin Trapping	1998
Acylated ascorbate stimulates collagen synthesis in cultured human foreskin fibroblasts at lower doses than does ascorbic acid. Connective tissue research, 1998, Volume: 37, Issue:3-4 Topics: Acylation; Antioxidants; Ascorbate Oxidase; Ascorbic Acid; Cells, Cultured; Collagen; Deferoxamine; DNA; Dose-Response Relationship, Drug; Fibroblasts; Humans; Hydroquinones; Oxidation-Reduction; Serum Albumin, Bovine; Skin; Time Factors	1998
Use of a laccase-column for flow-injection calorimetry. Annals of the New York Academy of Sciences, 1998, Dec-13, Volume: 864 Topics: Ascorbic Acid; Basidiomycota; Calorimetry; Catechols; Enzymes, Immobilized; Food Analysis; Hydroquinones; Laccase; Oxidoreductases; Substrate Specificity; Thermodynamics	1998
[Mechanism of combined oxidation of ascorbic acid and hydroquinone in the presence of horseradish peroxidase]. Bioorganicheskaia khimiia, 1999, Volume: 25, Issue:5 Topics: Ascorbic Acid; Horseradish Peroxidase; Hydroquinones; Kinetics; Oxidation-Reduction; Spectrophotometry, Ultraviolet	1999
Redox and fungicidal properties of phthalocyanine metal complexes as related to active oxygen. Journal of inorganic biochemistry, 2000, Oct-01, Volume: 81, Issue:4 Topics: Antioxidants; Ascorbic Acid; Catalysis; Dose-Response Relationship, Drug; Fungicides, Industrial; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; Indoles; Light; Magnaporthe; Metals; Organometallic Compounds; Oryza; Oxidation-Reduction; Plant Diseases; Plant Leaves; Superoxides; Toxicity Tests	2000
Polymer gels for magnetic resonance imaging of radiation dose distributions at normal room atmosphere. Physics in medicine and biology, 2001, Volume: 46, Issue:12 Topics: Ascorbic Acid; Copper; Dose-Response Relationship, Radiation; Gelatin; Gels; Hydroquinones; Ions; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Methacrylates; Phantoms, Imaging; Polymers; Pressure; Protons; Radiometry	2001
Intradermal concentration of hydroquinone after application of hydroquinone ointments is higher than its cytotoxic concentration. Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:9 Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cells, Cultured; Colorimetry; Diffusion; Fibroblasts; Hydroquinones; Male; Ointments; Rats; Rats, Wistar; Skin; Skin Absorption; Sulfates	2003
[Coupled oxidation of hydroquinone and ascorbic acid by polyphenoloxidase]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1961, Mar-27, Volume: 252 Topics: Ascorbic Acid; Catechol Oxidase; Humans; Hydroquinones; Oxidation-Reduction; Oxidoreductases; Phenols; Vitamins	1961
Oxygen uptake after electron transfer from amines, amino acids and ascorbic acid to triplet flavins in air-saturated aqueous solution. Journal of photochemistry and photobiology. B, Biology, 2007, May-25, Volume: 87, Issue:2 Topics: Air; Amines; Amino Acids; Ascorbic Acid; Electrons; Flavins; Hydroquinones; Oxygen; Photolysis; Solutions; Water	2007
Microplate-compatible biamperometry array for parallel 48-channel amperometric or coulometric measurements. Analytical chemistry, 2008, Apr-15, Volume: 80, Issue:8 Topics: Acetaminophen; Ascorbic Acid; Calibration; Chromans; Electrochemistry; Electrodes; Ferrocyanides; Glucose; Glucose Oxidase; Hydrogen Peroxide; Hydroquinones; Microchemistry; Oxidation-Reduction; Platinum; Uric Acid	2008
Mechanistic studies on the oxidation of ascorbic acid and hydroquinone by a {Mn4O6}4+ core in aqueous media. The journal of physical chemistry. A, 2011, May-19, Volume: 115, Issue:19 Topics: Ascorbic Acid; Hydroquinones; Manganese; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Quantum Theory; Water	2011
Ascorbic acid for homogenous redox buffering in electrospray ionization-mass spectrometry. Analytical and bioanalytical chemistry, 2012, Volume: 404, Issue:5 Topics: Antioxidants; Ascorbic Acid; Buffers; Equipment Design; Glutathione; Hydroquinones; Oxidation-Reduction; Pharmaceutical Preparations; Spectrometry, Mass, Electrospray Ionization	2012
Hydroquinone modified chitosan/carbon film electrode for the selective detection of ascorbic acid. Carbohydrate polymers, 2013, Jan-30, Volume: 92, Issue:1 Topics: Ascorbic Acid; Biosensing Techniques; Carbon; Chitosan; Hydroquinones; Microelectrodes; Nanocomposites; Polymers	2013
The effects of Sophora angustifolia and other natural plant extracts on melanogenesis and melanin transfer in human skin cells. Experimental dermatology, 2013, Volume: 22, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Actinidia; Ascorbic Acid; Cells, Cultured; Coculture Techniques; Fruit; Humans; Hydroquinones; Keratinocytes; Melanins; Melanocytes; Microscopy, Confocal; Morus; Niacinamide; Plant Extracts; Plant Leaves; Plant Roots; Sophora	2013
Polar paradox revisited: analogous pairs of hydrophilic and lipophilic antioxidants in linoleic acid emulsion containing Cu(II). Journal of the science of food and agriculture, 2013, Aug-15, Volume: 93, Issue:10 Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Chromans; Copper; Emulsions; Gallic Acid; Hydrophobic and Hydrophilic Interactions; Hydroquinones; Iron; Kinetics; Linoleic Acid; Lipid Peroxidation; Peroxides; Propyl Gallate; Structure-Activity Relationship; Thiobarbituric Acid Reactive Substances; Thiocyanates	2013
Tyrosinase-catalyzed hydroxylation of hydroquinone, a depigmenting agent, to hydroxyhydroquinone: A kinetic study. Bioorganic & medicinal chemistry, 2014, Jul-01, Volume: 22, Issue:13 Topics: Ascorbic Acid; Biocatalysis; Hydrogen Peroxide; Hydroquinones; Hydroxylation; Kinetics; Molecular Structure; Monophenol Monooxygenase; Skin Lightening Preparations	2014