hydromorphone and oxymorphone

hydromorphone has been researched along with oxymorphone in 124 studies

Research

Studies (124)

Timeframe	Studies, this research(%)	All Research%
pre-1990	89 (71.77)	18.7374
1990's	4 (3.23)	18.2507
2000's	8 (6.45)	29.6817
2010's	19 (15.32)	24.3611
2020's	4 (3.23)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B	1
Pasternak, GW; Snyder, SH; Wilson, HA	1
Johnstone, RE; Kulp, RA; Lief, PL; Smith, TC	1
Beaver, WT; Houde, RW; Rogers, A; Wallenstein, SL	1
Fishman, J; Foldes, FF; Hahn, EF; Ronai, AZ	1
Merz, H; Stockhaus, K; Wick, H	1
Berkowitz, DS; Loew, GH	1
Knoll, J	1
Bishop, P; Conner, R; Herman, B; Panksepp, J; Scott, JP	1
Molnár, L; Proksa, B; Putek, J; Stefek, M; Votický, Z	1
Caruso, TP; Larson, DL; Portoghese, PS; Takemori, AE	2
Coddington, JM; Gamble, GD; Milne, RJ	1
Angel, L; Appelmans, N; Gioannini, TL; Koolpe, GA; Nelson, WL; Simon, EJ	1
Archer, S; Corbett, AD; Kosterlitz, HW; McKnight, AT; Paterson, SJ; Seyed-Mozaffari, A; Ward, S	1
Bhatia, AV; Chang, KJ; Lever, OW	1
Goodman, RR; Hahn, EF; Nishimura, S; Pasternak, GW	1
Hahn, EF; Itzhak, Y; Johnson, N; Nishimura, S; Pasternak, GW	1
Randall, JI; Rodgers, RJ	1
Einarsson, M; Koman, A; Terenius, L	1
Berg, RJ; Orton, EC	1
Foley, KM; Inturrisi, CE; Moulin, DE; Portenoy, RK; Rogers, A	1
Chance, WT; Nelson, JL	1
Lam, G; Whitney, CC; Williams, RM	1
Benyhe, S; Borsodi, A; Hosztafi, S; Toth, G; Varga, E	1
Galetta, S; Hahn, EF; Nishimura, S; Pasternak, GW	1
Larson, DL; Lemieux, C; Nguyen, TM; Portoghese, PS; Ronsisvalle, G; Schiller, PW; Takemori, AE	1
Fanelli, RJ; Jasinski, DR; London, ED; Szikszay, M	1
Borsodi, A; Hosztafi, S; Toth, G; Varga, E	1
Fanelli, R; Jasinski, D; London, E; Szikszay, M	1
Copland, VS; Haskins, SC; Patz, JD	1
Patt, RB	1
Rogers, AG	1
Bodnar, RJ; Burks, TF; Clark, JE; Hahn, EF; Pasternak, GW; Williams, CL	1
Faggella, AM; Henry, DP; Robinson, EP; Russell, WL	1
Hand, TH; Koob, GF; Le Moal, M; Stinus, L	1
Chung, JH; Chung, KS; Harrison, DM; Lodge, K; Parker, A; Sibert, K; Sinatra, RS	1
Benyhe, S; Borsodi, A; Hoffmann, G; Hosztafi, S; Toth, G; Varga, E; Wollemann, M	1
Harrison, DM; Sinatra, RS	2
Botros, S; Larson, DL; Lipkowski, AW; Portoghese, PS; Stark, PA; Takemori, AE	1
Alexander, GJ; Chatterjie, N; Wisniewski, HM	1
Doze, VA; Shafer, A; Urquhart, ML; White, PF	1
Brull, SJ; Chung, J; Chung, KS; Donielson, D; Harrison, DM; Silverman, DG; Sinatra, R; Weinstock, A	1
Copland, VS; Haskins, SC; Patz, J	1
Ebertz, JM; Hanifin, JM; Hermens, JM; Hirshman, CA	1
Bowen, WD; Herkenham, M; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Abdelhamid, EM; Archer, S; Koolpe, GA; Michael, J; Michael, M; Nelson, WL; Simon, EJ	1
Gorodetzky, CW	1
Pasternak, G; Pert, CB; Snyder, SH	1
Brown, SS; Clarke, RS; Dundee, JW; Hamilton, RC; Loan, WB; Morrison, JD	1
Röthig, J	1
Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE	1
Hahn, EF; Pasternak, GW	1
Puget, A	1
Armstrong, MJ; Larson, AA	1
Chien, YW; Hurwitz, AR; Shami, EG; Van Nostrand, P	1
Blake, JW; Combie, J; Nugent, TE; Tobin, T	1
Chang, KJ; Cuatrecasas, P; Hazum, E; Leighton, HJ; Lever, OW	1
Carroll-Buatti, M; Hahn, EF; Pasternak, GW	1
Darling, SD; Kolb, VM; Mandel, GS; Mandel, NS	1
Hemmer, RC; Kastin, AJ; McLean, JH; Olson, GA; Olson, RD	1
Casanueva, F; Di Giulio, AM; Mantegazza, P; Martini, A; Panerai, AE; Petraglia, F	1
Bianchi, G; Ferretti, P; Manara, L; Recchia, M; Rocchetti, M; Tavani, A	1
Giles, T; Merz, H; Sander, G	1
Chi, CJ; Guo, YM; Liu, MQ; Zhu, CL	1
Cooper, SJ; Turkish, S	1
Dashwood, MR; Kiang, JG; Wei, ET	1
Breese, CE; Dodman, NH	1
Jacob, JJ; Rios, L	1
Galetta, S; Ling, GS; Pasternak, GW	1
France, CP; Jacobson, AE; Woods, JH	2
Burke, TR; Danks, JA; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Barber, DL; Barsanti, JA; Crowell, WA; Mahaffey, MB	1
Angel, L; Gioannini, TL; Koolpe, GA; Nelson, WL; Simon, EJ	1
Dietzen, DJ; Koenig, J; Turk, J	1
Fang, X; Larson, DL; Portoghese, PS	1
Bohrer, A; Koenig, J; Nowatzke, W; Saunders, A; Turk, J; Zeng, J	1
Dyson, D; Pettifer, G	1
Bjorling, DE; Smith, LJ; Waller, K; Yu, JK	1
EDDY, NB; LEE, LE	1
KNAFF, M; RONDEAU, Y	1
TULLAR, PE	1
FOLDES, FF; KLEIN, S; LUNN, JN; SIKER, ES	1
KOHL, SG; SENTNOR, MH; SOLOMONS, E	1
SATTENSPIEL, E; SNOW, DL	1
HOMI, J; WASMUTH, CE	1
KOSTYAL, JL	1
CASS, LJ; FREDERIK, WS	1
WANG, RI	1
LASAGNA, L	1
KOBAYASHI, S; SEKI, I; TAKAGI, H	1
SEIGLEMAN, M; WASMUTH, CE	1
NICHOLS, EE; POOL, E; SHAW, W; SIMECKOVA, M	1
KANE, AA	1
Ananthan, S; Bartlett, JL; Bilsky, EJ; Davis, P; Dersch, CM; Khare, NK; Porreca, F; Rothman, RB; Saini, SK; Seitz, LE	1
Dyson, DH; Machado, CG; Mathews, KA	1
Dyson, DH; Grant Maxie, M; Machado, CE	1
Bateman, SW; Haldane, S; Stephens, JA	1
Black, D; Caplan, YH; Cone, EJ; Moser, F; Robert, T	1
Dahn, T; Gunn, J; Kriger, S; Terrell, AR	1
Gingras, M; Laberge, MH; Lefebvre, M	1
Gould, EM; Peniston, JH; Xiang, Q	1
Alford, I; Shan, X; Tiscione, NB; Yeatman, DT	1
French, D; Lynch, K; Wu, A	1
Heath, TD; Krugner-Higby, LA; Kukanich, BK; Schmidt, BH; Smith, LJ	1
Ilkiw, JE; Pypendop, BH; Shilo-Benjamini, Y	2
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M	1
Bernardy, K; Häuser, W; Maier, C	1
Barr, JW; Horsley, KT; Lepiz, MA; Pashmakova, MB; Sayre, RS; Washburn, SE	1
ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B	1
Darragh, A; Lee, LA; Marinova, M; Mastrianni, KR; Melendez, C; Ryan, E; Sitasuwan, P	1
Dasgupta, A; Dixon, RB	1
Bynum, ND; Flegel, R; Grabenauer, M; Hayes, ED; Mitchell, JM; Moore, KN; White, RM	1
Guevara, M; Hofilena, D; Mikel, C; West, R	1
Dani, M; Kennedy, D	1
Eidbo, SA; Hagedorn, JD; Kaufman, DE; Kropp Lopez, AK; Mathew, V; McCall, KL; Nichols, SD; Piper, BJ	1
Coulter, C; Garnier, M; Moore, C	1
Cassella-Mclane, G; Choucair, I; Durant, TJS; El-Khoury, JM; Vera, MA; Villalba, CF	1

Reviews

5 review(s) available for hydromorphone and oxymorphone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Analgesics. 32]. Pharmazeutische Praxis, 1969, Volume: 5 Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine	1969
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS. Pharmacological reviews, 1964, Volume: 16 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology	1964
[Long-term opioid therapy in chronic noncancer pain. A systematic review and meta-analysis of efficacy, tolerability and safety in open-label extension trials with study duration of at least 26 weeks]. Schmerz (Berlin, Germany), 2015, Volume: 29, Issue:1 Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Hydromorphone; Long-Term Care; Morphine; Oxycodone; Oxymorphone; Pain Measurement; Phenols; Randomized Controlled Trials as Topic; Tapentadol; Tramadol; Treatment Outcome	2015

Trials

14 trial(s) available for hydromorphone and oxymorphone

Article	Year
Combination of delta9-tetrahydrocannabinol with oxymorphone or pentobarbital: Effects on ventilatory control and cardiovascular dynamics. Anesthesiology, 1975, Volume: 42, Issue:6 Topics: Adult; Blood Pressure; Cannabis; Cardiac Output; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Emotions; Heart Rate; Hemodynamics; Humans; Hydromorphone; Injections, Intravenous; Male; Nausea; Oxymorphone; Pentobarbital; Pulmonary Ventilation; Respiration; Vascular Resistance	1975
Comparisons of the analgesic effects of oral and intramuscular oxymorphone and of intramuscular oxymorphone and morphine in patients with cancer. Journal of clinical pharmacology, 1977, Volume: 17, Issue:4 Topics: Administration, Oral; Adult; Aged; Analgesics; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hydromorphone; Injections, Intramuscular; Male; Middle Aged; Morphine; Neoplasms; Oxymorphone; Pain; Placebos; Time Factors	1977
A comparison of morphine, meperidine, and oxymorphone as utilized in patient-controlled analgesia following cesarean delivery. Anesthesiology, 1989, Volume: 70, Issue:4 Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Clinical Trials as Topic; Female; Humans; Hydromorphone; Meperidine; Morphine; Oxymorphone; Pain, Postoperative; Pregnancy; Random Allocation; Self Administration	1989
Outpatient premedication: use of midazolam and opioid analgesics. Anesthesiology, 1989, Volume: 71, Issue:4 Topics: Adult; Ambulatory Surgical Procedures; Double-Blind Method; Drug Combinations; Female; Fentanyl; Humans; Hydromorphone; Intraoperative Period; Male; Midazolam; Oxymorphone; Preanesthetic Medication; Randomized Controlled Trials as Topic	1989
An evaluation of morphine and oxymorphone administered via patient-controlled analgesia (PCA) or PCA plus basal infusion in postcesarean-delivery patients. Anesthesiology, 1989, Volume: 71, Issue:4 Topics: Cesarean Section; Female; Humans; Hydromorphone; Infusion Pumps; Morphine; Oxymorphone; Pain, Postoperative; Pregnancy; Randomized Controlled Trials as Topic; Self Administration	1989
A comparison of oxymorphone and fentanyl as narcotic supplements in general anesthesia. Journal of clinical anesthesia, 1989, Volume: 1, Issue:4 Topics: Anesthesia, General; Double-Blind Method; Drug Evaluation; Female; Fentanyl; Genital Diseases, Female; Hemodynamics; Humans; Hydromorphone; Oxymorphone; Randomized Controlled Trials as Topic	1989
Studies of drugs given before anaesthesia. XVII: The natural and semi-synthetic opiates. British journal of anaesthesia, 1969, Volume: 41, Issue:1 Topics: Clinical Trials as Topic; Codeine; Female; Heroin; Humans; Hydromorphone; Morphine; Oxymorphone; Placebos; Preanesthetic Medication	1969
Effects of hydromorphone or oxymorphone, with or without acepromazine, on preanesthetic sedation, physiologic values, and histamine release in dogs. Journal of the American Veterinary Medical Association, 2001, Apr-01, Volume: 218, Issue:7 Topics: Acepromazine; Analgesics, Opioid; Animals; Blood Pressure; Dogs; Dopamine Antagonists; Drug Combinations; Heart Rate; Histamine; Histamine Release; Hydromorphone; Injections, Intramuscular; Male; Oxymorphone	2001
Effects of oxymorphone and hydromorphone on the minimum alveolar concentration of isoflurane in dogs. Veterinary anaesthesia and analgesia, 2006, Volume: 33, Issue:1 Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dogs; Female; Hydromorphone; Isoflurane; Male; Oxymorphone; Pulmonary Alveoli	2006
Comparison of the analgesic efficacy of hydromorphone and oxymorphone in dogs and cats: a randomized blinded study. Veterinary anaesthesia and analgesia, 2008, Volume: 35, Issue:4 Topics: Analgesics, Opioid; Animals; Cats; Costs and Cost Analysis; Dogs; Female; Hydromorphone; Male; Oxymorphone; Pain Measurement; Pain, Postoperative; Treatment Outcome	2008
Evidence that morphine is metabolized to hydromorphone but not to oxymorphone. Journal of analytical toxicology, 2008, Volume: 32, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Hydromorphone; Male; Middle Aged; Morphine; Oxymorphone; Pain	2008
Bioavailability of morphine, methadone, hydromorphone, and oxymorphone following buccal administration in cats. Journal of veterinary pharmacology and therapeutics, 2014, Volume: 37, Issue:3 Topics: Administration, Buccal; Analgesics, Opioid; Animals; Biological Availability; Cats; Female; Hydromorphone; Methadone; Morphine; Oxymorphone	2014
Effects of oxymorphone hydrochloride or hydromorphone hydrochloride on minimal alveolar concentration of desflurane in sheep. American journal of veterinary research, 2015, Volume: 76, Issue:7 Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cardiac Output; Cross-Over Studies; Desflurane; Female; Hydromorphone; Infusions, Intravenous; Isoflurane; Oxymorphone; Pulmonary Alveoli; Sheep	2015
Effect of morphine, methadone, hydromorphone or oxymorphone on the thermal threshold, following intravenous or buccal administration to cats. Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:6 Topics: Administration, Buccal; Administration, Intravenous; Analgesics, Opioid; Animals; Cats; Cross-Over Studies; Female; Hydromorphone; Methadone; Morphine; Oxymorphone; Pain Threshold	2016

Other Studies

105 other study(ies) available for hydromorphone and oxymorphone

Article	Year
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1. Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21 Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation	2019
Differentiation of opiate agonist and antagonist receptor binding by protein modifying reagents. Nature, 1975, Feb-06, Volume: 253, Issue:5491 Topics: Animals; Binding Sites; Brain; Chloromercuribenzoates; Ethylmaleimide; Hydromorphone; In Vitro Techniques; Iodoacetates; Levallorphan; Levorphanol; Naloxone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Receptors, Drug; Structure-Activity Relationship; Sulfhydryl Reagents; Tritium	1975
Orientation of the oxygen atom at C-6 as a determinant of agonistic activity in the oxymorphone series. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:3 Topics: Animals; Guinea Pigs; Hydromorphone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oxygen; Oxymorphone; Structure-Activity Relationship	1977
Diastereoisomeric N-tetrahydrofurfurylnoroxymorphones with opioid agonist--antagonist properties. Journal of medicinal chemistry, 1977, Volume: 20, Issue:6 Topics: Analgesia; Animals; Furans; Guinea Pigs; Haplorhini; Hydromorphone; In Vitro Techniques; Macaca mulatta; Mice; Morphine; Narcotic Antagonists; Narcotics; Oxymorphone; Reaction Time; Stereoisomerism; Structure-Activity Relationship	1977
Quantum chemical studies of N-substituent variation in the oxymorphone series of opiate narcotics. Journal of medicinal chemistry, 1978, Volume: 21, Issue:1 Topics: Analgesics, Opioid; Animals; Hydromorphone; In Vitro Techniques; Mice; Molecular Conformation; Oxymorphone; Quantum Theory; Rats; Structure-Activity Relationship; Swine; Thermodynamics	1978
Azidomorphines and homopyrimidazols: a new approach to the ideal analgetic. Acta physiologica et pharmacologica Bulgarica, 1977, Volume: 3, Issue:2 Topics: Analgesics; Animals; Drug Synergism; Haplorhini; Humans; Hydromorphone; Macaca mulatta; Male; Morphine; Morphine Derivatives; Oxymorphone; Pyrimidines; Pyrimidinones; Rats; Respiration; Substance-Related Disorders	1977
The biology of social attachments: opiates alleviate separation distress. Biological psychiatry, 1978, Volume: 13, Issue:5 Topics: Animals; Anxiety, Separation; Body Temperature; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Humans; Hydromorphone; Morphine; Motor Activity; Oxymorphone; Social Behavior; Vocalization, Animal	1978
10-oxomorphine, a decomposition product of morphine. Die Pharmazie, 1978, Volume: 33, Issue:9 Topics: Chemical Phenomena; Chemistry; Hydromorphone; Morphine; Oxymorphone	1978
Chloroxymorphamine, and opioid receptor site-directed alkylating agent having narcotic agonist activity. Science (New York, N.Y.), 1979, Apr-20, Volume: 204, Issue:4390 Topics: Alkylating Agents; Animals; Chlorambucil; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Hydromorphone; In Vitro Techniques; Morphine; Naloxone; Naltrexone; Nitrogen Mustard Compounds; Norepinephrine; Oxymorphone; Phenoxybenzamine; Receptors, Opioid	1979
Quaternary naloxone blocks morphine analgesia in spinal but not intact rats. Neuroscience letters, 1990, Jul-13, Volume: 114, Issue:3 Topics: Animals; Denervation; Female; Hydromorphone; Morphine; Oxymorphone; Pain; Permeability; Rats; Rats, Inbred Strains; Spinal Cord	1990
Opioid agonists and antagonists. 6-Desoxy-6-substituted lactone, epoxide, and glycidate ester derivatives of naltrexone and oxymorphone. Journal of medicinal chemistry, 1985, Volume: 28, Issue:7 Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Circular Dichroism; Epoxy Compounds; Ethers, Cyclic; Hydromorphone; Lactones; Male; Naloxone; Naltrexone; Oxymorphone; Propionates; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship	1985
10-Ketonaltrexone and 10-ketooxymorphone. Journal of medicinal chemistry, 1985, Volume: 28, Issue:7 Topics: Animals; Biological Assay; Brain; Chemical Phenomena; Chemistry; Guinea Pigs; Hydromorphone; Ileum; Male; Mice; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens	1985
Opioid receptor interactions and conformations of the 6 alpha and 6 beta epimers of oxymorphamine. Solid-state conformation of 6 alpha-oxymorphamine. Journal of medicinal chemistry, 1985, Volume: 28, Issue:11 Topics: Animals; Brain; Hydromorphone; Isomerism; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxymorphone; Rats; Receptors, Opioid; Structure-Activity Relationship	1985
Irreversible opiate agonists and antagonists. II. Evidence against a bivalent mechanism of action for opiate azines and diacylhydrazones. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Animals; Binding, Competitive; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship	1985
Irreversible opiate agonists and antagonists. III. Phenylhydrazone derivatives of naloxone and oxymorphone. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Albumins; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship; Tritium	1985
Social conflict analgesia: studies on naloxone antagonism and morphine cross-tolerance in male DBA/2 mice. Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:5 Topics: Analgesia; Animals; Conflict, Psychological; Drug Tolerance; Hydromorphone; Male; Mice; Mice, Inbred DBA; Morphine; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Oxymorphone	1985
Agonist-antagonist properties of fluorescent opioid probes in the guinea-pig myenteric plexus-longitudinal muscle preparation. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:4 Topics: Animals; Chemical Phenomena; Chemistry; Depression, Chemical; Fluorescent Dyes; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Male; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Stereoisomerism; Stimulation, Chemical	1985
Pulmonary function in dogs after intercostal thoracotomy: comparison of morphine, oxymorphone, and selective intercostal nerve block. American journal of veterinary research, 1986, Volume: 47, Issue:2 Topics: Animals; Bupivacaine; Carbon Dioxide; Dogs; Female; Hydromorphone; Lung; Male; Morphine; Nerve Block; Oxygen; Oxymorphone; Partial Pressure; Respiration; Respiratory Function Tests; Ribs; Thoracic Surgery	1986
I.v. infusion of opioids for cancer pain: clinical review and guidelines for use. Cancer treatment reports, 1986, Volume: 70, Issue:5 Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Administration Schedule; Drug Evaluation; Humans; Hydromorphone; Infant; Infusions, Parenteral; Levorphanol; Methadone; Middle Aged; Morphine; Narcotics; Neoplasms; Oxymorphone; Pain, Intractable; Palliative Care; Retrospective Studies	1986
Antagonism of stress-induced analgesia by quaternary naloxone. Brain research, 1986, Aug-20, Volume: 380, Issue:2 Topics: Analgesia; Animals; Drug Interactions; Electroshock; Hydromorphone; Male; Morphine; Oxymorphone; Pain; Rats; Rats, Inbred Strains; Reaction Time; Stress, Physiological	1986
Electrochemical determination of oxymorphone in rat plasma by ion-pair reversed-phase high-performance liquid chromatography. Journal of chromatography, 1987, Jan-23, Volume: 413 Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Hydrogen-Ion Concentration; Hydromorphone; Kinetics; Male; Oxymorphone; Rats; Rats, Inbred Strains	1987
Synthesis and binding of 3H-oxymorphazone to rat brain membranes. Life sciences, 1987, Apr-20, Volume: 40, Issue:16 Topics: Animals; Binding, Competitive; Brain; Hydromorphone; In Vitro Techniques; Isotope Labeling; Kinetics; Naloxone; Oxymorphone; Radioligand Assay; Rats; Receptors, Opioid; Tritium	1987
Oxymorphone-naltrexonazine, a mixed opiate agonist-antagonist. Life sciences, 1987, Aug-10, Volume: 41, Issue:6 Topics: Analgesia; Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; Male; Mice; Mice, Inbred ICR; Naltrexone; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium	1987
Hybrid bivalent ligands with opiate and enkephalin pharmacophores. Journal of medicinal chemistry, 1987, Volume: 30, Issue:11 Topics: Analgesics; Animals; Enkephalins; Guinea Pigs; Hydromorphone; Ligands; Male; Mice; Muscle, Smooth; Naloxone; Oxymorphone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Differential effects of mu and kappa opioid analgesics on cerebral glucose utilization in the rat. Brain research, 1987, Oct-06, Volume: 422, Issue:2 Topics: Animals; Autoradiography; Blood Pressure; Brain; Carbon Dioxide; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; Heart Rate; Hydromorphone; Male; Morphinans; Morphine; Nalbuphine; Organ Specificity; Oxygen; Oxymorphone; Rats; Rats, Inbred F344; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1987
Preparation of [3H]-oxymorphazone and its binding to rat brain membranes. NIDA research monograph, 1986, Volume: 75 Topics: Animals; Brain; Cell Membrane; Hydromorphone; Kinetics; Oxymorphone; Rats; Receptors, Opioid	1986
Effects of opioid analgesics on local cerebral glucose utilization. NIDA research monograph, 1986, Volume: 75 Topics: Animals; Brain; Deoxy Sugars; Deoxyglucose; Hydromorphone; Male; Morphinans; Morphine; Nalbuphine; Organ Specificity; Oxymorphone; Rats; Rats, Inbred F344	1986
Oxymorphone: cardiovascular, pulmonary, and behavioral effects in dogs. American journal of veterinary research, 1987, Volume: 48, Issue:11 Topics: Animals; Behavior, Animal; Cardiovascular System; Dogs; Female; Hydromorphone; Injections, Intravenous; Male; Oxymorphone; Respiration	1987
Delayed postoperative respiratory depression associated with oxymorphone. Anesthesia and analgesia, 1988, Volume: 67, Issue:4 Topics: Anesthesia; Female; Humans; Hydromorphone; Middle Aged; Oxymorphone; Postoperative Complications; Respiration; Time Factors	1988
When all oral opioids cause nausea and vomiting. Journal of pain and symptom management, 1988,Spring, Volume: 3, Issue:2 Topics: Adult; Analgesics, Opioid; Female; Humans; Hydromorphone; Oxymorphone; Suppositories; Vomiting	1988
Irreversible opiate agonists and antagonists. IV. Analgesic actions of 14-hydroxydihydromorphinone hydrazones. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1 Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; Male; Mice; Naloxone; Oxymorphone; Receptors, Opioid; Time Factors	1988
Comparison of histamine release induced by morphine and oxymorphone administration in dogs. American journal of veterinary research, 1988, Volume: 49, Issue:10 Topics: Animals; Dogs; Female; Histamine; Histamine Release; Hydromorphone; Injections, Intravenous; Male; Morphine; Oxymorphone; Random Allocation	1988
Aversive properties of opiate receptor blockade: evidence for exclusively central mediation in naive and morphine-dependent rats. Brain research, 1988, Dec-06, Volume: 474, Issue:2 Topics: Animals; Avoidance Learning; Conditioning, Classical; Dose-Response Relationship, Drug; Hydromorphone; Injections, Intraventricular; Injections, Subcutaneous; Morphine; Oxymorphone; Rats; Receptors, Opioid	1988
Effects of oxymorphazone in frogs: long lasting antinociception in vivo, and apparently irreversible binding in vitro. Life sciences, 1989, Volume: 44, Issue:24 Topics: Analgesics; Animals; Binding, Competitive; Brain; Cell Membrane; Dose-Response Relationship, Drug; Hydromorphone; Kinetics; Naloxone; Oxymorphone; Rana esculenta; Receptors, Opioid; Spinal Cord	1989
Oxymorphone in patient-controlled analgesia. Clinical pharmacy, 1989, Volume: 8, Issue:8 Topics: Cesarean Section; Female; Humans; Hydromorphone; Morphine; Oxymorphone; Pain, Postoperative; Self Administration	1989
Opioid agonist and antagonist activities of peripherally selective derivatives of naltrexamine and oxymorphamine. Journal of medicinal chemistry, 1989, Volume: 32, Issue:9 Topics: Animals; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Guinea Pigs; Hydromorphone; Male; Mice; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Oxymorphone; Pain; Structure-Activity Relationship	1989
A spirohydantoin derivative of oxymorphone: an agonist with delayed antagonist activity. Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4 Topics: Analgesia; Animals; Anticonvulsants; Behavior, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation, Preclinical; Hydantoins; Hydromorphone; Male; Mice; Morphine; Oxymorphone; Pain; Sensory Thresholds; Time Factors	1989
Naloxone reversal of oxymorphone effects in dogs. American journal of veterinary research, 1989, Volume: 50, Issue:11 Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; Heart; Heart Rate; Hydromorphone; Naloxone; Oxygen; Oxymorphone; Pulmonary Wedge Pressure; Respiration; Tidal Volume; Vascular Resistance	1989
Comparison of histamine release in human skin mast cells induced by morphine, fentanyl, and oxymorphone. Anesthesiology, 1985, Volume: 62, Issue:2 Topics: Cell Membrane; Dose-Response Relationship, Drug; Fentanyl; Histamine; Histamine Release; Humans; Hydromorphone; Leukocytes; Mast Cells; Morphine; Naloxone; Oxymorphone; Receptors, Opioid; Skin	1985
A quantitative study of [3H]D-Ala2-D-Leu5-enkephalin binding to rat brain membranes. Evidence that oxymorphone is a noncompetitive inhibitor of the lower affinity delta-binding site. Molecular pharmacology, 1985, Volume: 27, Issue:3 Topics: Animals; Autoradiography; Brain; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Hydromorphone; Male; Manganese; Manganese Compounds; Mathematics; Membranes; Oligopeptides; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride	1985
Chloroacryloyl amides and alpha-methylenelactones from naltrexone, oxymorphone and fentanyl. Neuropeptides, 1985, Volume: 5, Issue:4-6 Topics: Acrylates; Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Fentanyl; Hydromorphone; In Vitro Techniques; Membranes; Naloxone; Naltrexone; Oxymorphone; Rats; Stereoisomerism	1985
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine. Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3 Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine	1972
Opiate agonists and antagonists discriminated by receptor binding in brain. Science (New York, N.Y.), 1973, Dec-28, Volume: 182, Issue:4119 Topics: Analgesics; Animals; Binding, Competitive; Brain; Hydromorphone; In Vitro Techniques; Levallorphan; Levorphanol; Mice; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Oxymorphone; Receptors, Drug; Sodium; Tritium	1973
Opiates and thermoregulation in mice. I. Agonists. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2 Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone	1980
Long-acting opiate agonists and antagonists: 14-hydroxydihydromorphinone hydrazones. Journal of medicinal chemistry, 1980, Volume: 23, Issue:6 Topics: Analgesics, Opioid; Animals; Brain; Delayed-Action Preparations; Hydrazones; Hydromorphone; In Vitro Techniques; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oxymorphone; Rats; Receptors, Opioid	1980
[Analgesic activity of various morphine derivatives on the Afghan pika (Ochotona rufescens rufescens): tolerance of the acute effects of morphine]. Zentralblatt fur Veterinarmedizin. Reihe A, 1980, Volume: 27, Issue:2 Topics: Analgesia; Animals; Hydromorphone; Lagomorpha; Mammals; Morphine; Oxymorphone	1980
Morphine analgesia after intrathecal administration of a narcotic agonist, chloroxymorphamine and antagonist, chlornaltrexamine. European journal of pharmacology, 1980, Nov-07, Volume: 68, Issue:1 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Hydromorphone; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nitrogen Mustard Compounds; Oxymorphone; Rats	1980
Pharmacological studies with an alkylating narcotic agonist, chloroxymorphamine, and antagonist, chlornaltrexamine. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:3 Topics: Analgesics; Animals; Brain; Hydromorphone; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nitrogen Mustard Compounds; Oxymorphone	1980
Drug--disintegrant interactions: binding of oxymorphone derivatives. Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:6 Topics: Excipients; Hydrogen-Ion Concentration; Hydromorphone; Oxymorphone; Tablets	1981
Furosemide, Patella vulgata beta-glucuronidase and drug analysis: conditions for enhancement of the TLC detection of apomorphine, butorphanol, hydromorphone, nalbuphine, oxymorphone and pentazocine in equine urine. Research communications in chemical pathology and pharmacology, 1982, Volume: 35, Issue:1 Topics: Animals; Apomorphine; Butorphanol; Cattle; Chromatography, Thin Layer; Female; Furosemide; Glucuronidase; Helix, Snails; Horses; Hydrolysis; Hydromorphone; Mollusca; Nalbuphine; Oxymorphone; Pentazocine; Species Specificity	1982
Increased biological activity of dimers of oxymorphone and enkephalin: possible role of receptor crosslinking. Biochemical and biophysical research communications, 1982, Jan-15, Volume: 104, Issue:1 Topics: Animals; Binding, Competitive; Biological Assay; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Endorphins; Enkephalins; Guinea Pigs; Hydromorphone; Ileum; Kinetics; Muscle Contraction; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship	1982
Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1982, Volume: 2, Issue:5 Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Drug Stability; Hydromorphone; Kinetics; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship	1982
Operation of long-range substituent effects in rigid opiates: protonated and unprotonated oxymorphone. Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:7 Topics: Chemistry, Pharmaceutical; Hydromorphone; Molecular Conformation; Narcotics; Oxymorphone; Protons; X-Ray Diffraction	1982
Effects of naloxone and its quaternary form on fluid consumption in rats. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Drinking; Hydromorphone; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Oxymorphone; Rats; Rats, Inbred Strains	1982
Opiates and their antagonists modulate luteinizing hormone acting outside the blood brain barrier. Life sciences, 1983, Apr-11, Volume: 32, Issue:15 Topics: Animals; Blood-Brain Barrier; Castration; Dose-Response Relationship, Drug; Female; Hydromorphone; Luteinizing Hormone; Male; Morphine; Oxymorphone; Rats; Rats, Inbred Strains	1983
Morphine tissue levels and reduction of gastrointestinal transit in rats. Correlation supports primary action site in the gut. Gastroenterology, 1983, Volume: 85, Issue:4 Topics: Animals; Brain; Gastrointestinal Motility; Hydromorphone; Intestine, Small; Male; Morphine; Oxymorphone; Peristalsis; Rats	1983
Quaternary opiate antagonists lower blood pressure and inhibit leucine-enkephalin responses. European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4 Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Enkephalin, Leucine; Heart Rate; Hydromorphone; Naloxone; Naltrexone; Oxymorphone; Quaternary Ammonium Compounds	1983
[Synthesis of long-acting analgesic hydrazone derivatives of 14-hydroxycodeinone and 14-hydroxymorphine]. Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:6 Topics: Analgesics; Animals; Codeine; Hydromorphone; Mice; Oxycodone; Oxymorphone	1983
Fluid consumption in water-deprived rats after administration of naloxone or quaternary naloxone. Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6 Topics: Animals; Drinking; Hydromorphone; Male; Muridae; Naloxone; Oxymorphone; Receptors, Opioid; Taste; Thirst; Water Deprivation	1983
An etorphine-evoked vagal reflex in rats is inhibited by naloxone, N-methylnaloxone, and SMS 201-995. Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 266, Issue:1 Topics: Animals; Blood Pressure; Etorphine; Heart Rate; Hydromorphone; Male; Morphinans; Naloxone; Octreotide; Oxymorphone; Rats; Rats, Inbred Strains; Reflex; Respiration; Somatostatin; Vagus Nerve	1983
Xylazine-ketamine-oxymorphone: an injectable anesthetic combination in swine. Journal of the American Veterinary Medical Association, 1984, Jan-15, Volume: 184, Issue:2 Topics: Anesthesia, Intravenous; Animals; Drug Combinations; Heart Rate; Hydromorphone; Ketamine; Oxymorphone; Respiration; Swine; Thiazines; Xylazine	1984
Local inhibition of inflammatory pain by naloxone and its N-methyl quaternary analogue. European journal of pharmacology, 1983, Dec-23, Volume: 96, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Foot; Hydromorphone; Injections, Subcutaneous; Male; Morphine; Naloxone; Nociceptors; Oxymorphone; Rats; Rats, Inbred Strains	1983
Oxymorphazone: a long-acting opiate analgesic. Cellular and molecular neurobiology, 1984, Volume: 4, Issue:1 Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Methionine; Hydromorphone; Injections, Intraventricular; Morphine; Naloxone; Oxymorphone; Rats; Receptors, Opioid; Time Factors	1984
Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3 Topics: Animals; Buprenorphine; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Hydromorphone; Morphinans; Morphine; Naltrexone; Oxymorphone; Time Factors	1984
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding. Neuropeptides, 1984, Volume: 4, Issue:4 Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hydromorphone; Isothiocyanates; Kinetics; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Tomography, Emission-Computed	1984
Irreversible and reversible narcotic agonists: discriminative and analgesic effects of buprenorphine, oxymorphazone, and morphine. NIDA research monograph, 1984, Volume: 49 Topics: Animals; Buprenorphine; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Hydromorphone; Mice; Morphinans; Morphine; Naltrexone; Nociceptors; Oxymorphone	1984
Cystometry in dogs under oxymorphone and acepromazine restraint. American journal of veterinary research, 1984, Volume: 45, Issue:10 Topics: Acepromazine; Animals; Body Weight; Dogs; Drug Combinations; Female; Hydromorphone; Immobilization; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Oxymorphone; Pressure; Reflex; Urinary Bladder; Urinary Catheterization	1984
Diastereomeric 6-desoxy-6-spiro-alpha-methylene-gamma-butyrolactone derivatives of naltrexone and oxymorphone. Selective irreversible inhibition of naltrexone binding in an opioid receptor preparation by a conformationally restricted michael acceptor liga Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Brain; Cell Membrane; Chromatography, Thin Layer; Hydromorphone; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Conformation; Naloxone; Naltrexone; Narcotic Antagonists; Optical Rotation; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship	1984
Facilitation of thin-layer chromatographic identification of opiates by derivatization with acetic anhydride or methoxyamine. Journal of analytical toxicology, 1995, Volume: 19, Issue:5 Topics: Acetic Anhydrides; Chromatography, Thin Layer; Codeine; Humans; Hydrocodone; Hydromorphone; Hydroxylamines; Indicators and Reagents; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone	1995
7-spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands. Journal of medicinal chemistry, 1997, Sep-12, Volume: 40, Issue:19 Topics: Animals; Electric Stimulation; Guinea Pigs; Hydromorphone; In Vitro Techniques; Ligands; Male; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotics; Oxymorphone; Receptors, Opioid, delta; Spiro Compounds; Structure-Activity Relationship	1997
Distinction among eight opiate drugs in urine by gas chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis, 1999, Volume: 20, Issue:5 Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Molecular Structure; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone	1999
Hydromorphone: a cost-effective alternative to the use of oxymorphone. The Canadian veterinary journal = La revue veterinaire canadienne, 2000, Volume: 41, Issue:2 Topics: Analgesics, Opioid; Animals; Cat Diseases; Cats; Cost-Benefit Analysis; Dog Diseases; Dogs; Hydromorphone; Oxymorphone; Veterinary Medicine	2000
The analgesic equivalence to morphine and relative side action liability of oxymorphone (14-hydroxydihydro morphinone). The Journal of pharmacology and experimental therapeutics, 1959, Volume: 125, Issue:2 Topics: Analgesics; Humans; Hydromorphone; Morphine; Oxymorphone	1959
[Combined anesthesia with pentothal-numorphan-N2-O]. Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg, 1961, Volume: 98 Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Barbiturates; Hydromorphone; Nitrous Oxide; Oxymorphone; Pain Management; Thiopental	1961
Comparative toxicities of 14-hydroxydihydromorphinone (oxymorphone) and other narcotic analgesic compounds. Toxicology and applied pharmacology, 1961, Volume: 3 Topics: Hydromorphone; Narcotics; Oxymorphone	1961
The respiratory effects of oxymorphone administered alone or in combination with levallorphan. The American journal of the medical sciences, 1962, Volume: 243 Topics: Humans; Hydromorphone; Levallorphan; Morphine; Oxymorphone; Respiration	1962
An evaluation of oxymorphone in labor. American journal of obstetrics and gynecology, 1962, Oct-01, Volume: 84 Topics: Anesthesia; Anesthesia, Obstetrical; Anesthesiology; Female; Humans; Hydromorphone; Labor, Obstetric; Obstetrics; Oxymorphone; Pregnancy	1962
Report on oxymorphone in obstetrics. American journal of obstetrics and gynecology, 1962, Jan-01, Volume: 83 Topics: Anesthesia; Anesthesia, Obstetrical; Anesthesiology; Hydromorphone; Obstetrics; Oxymorphone	1962
A review of oxymorphone hydrochloride (Numorphan) analgesia employed for general surgery, including clinical experience with five hundred and twenty-eight patients. Cleveland Clinic quarterly, 1961, Volume: 28 Topics: Analgesia; Humans; Hydromorphone; Oxymorphone; Pain; Pain Management	1961
Oxymorphone during parturition, its effect on the newborn. Pennsylvania medical journal (1928), 1963, Volume: 66 Topics: Anesthesia; Anesthesia, Obstetrical; Delivery, Obstetric; Female; Humans; Hydromorphone; Infant, Newborn; Obstetrics; Oxymorphone; Parturition; Pregnancy	1963
THE CONTROL OF SEVERE PAIN WITH ORAL OXYMORPHONE HYDROCHLORIDE. Current therapeutic research, clinical and experimental, 1963, Volume: 5 Topics: Adolescent; Geriatrics; Humans; Hydromorphone; Meperidine; Oxymorphone; Pain; Toxicology	1963
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS. Wisconsin medical journal, 1964, Volume: 63 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pain; Phenazocine; Piperidines	1964
[PHARMACOLOGICAL STUDIES ON MORPHINE DERIVATIVES. 3. ON THE CHEMICAL STRUCTURE-ACTIVITY RELATIONSHIPS OF 14-HYDROXYMORPHINE DERIVATIVES]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1964, Volume: 84 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antitussive Agents; Codeine; Hydromorphone; Morphine; Morphine Derivatives; Nalorphine; Oxymorphone; Pharmacology; Research; Structure-Activity Relationship; Toxicology	1964
The use of oxymorphone hydrochloride during anesthesia for operations on the head and neck. A preliminary report. Cleveland Clinic quarterly, 1960, Volume: 27 Topics: Anesthesia; Anesthesiology; Head; Humans; Hydromorphone; Neck; Oxymorphone	1960
Numorphan in labor. A preliminary report. Obstetrics and gynecology, 1960, Volume: 16 Topics: Anesthesia; Anesthesia, Obstetrical; Female; Humans; Hydromorphone; Labor, Obstetric; Obstetrics; Oxymorphone; Pregnancy	1960
A peri-surgical evaluation of oxymorphone. Western medicine; the medical journal of the west, 1962, Volume: 3 Topics: Humans; Hydromorphone; Oxymorphone; Surgical Procedures, Operative	1962
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone]. Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6 Topics: Analgesics; Animals; Binding Sites; Brain; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Oxymorphone; Pyridines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens	2004
Evaluation of induction by use of a combination of oxymorphone and diazepam or hydromorphone and diazepam and maintenance of anesthesia by use of isoflurane in dogs with experimentally induced hypovolemia. American journal of veterinary research, 2005, Volume: 66, Issue:7 Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Animals; Blood Pressure; Body Temperature; Diazepam; Dog Diseases; Dogs; Female; Heart Rate; Hydromorphone; Hypovolemia; Isoflurane; Male; Oxymorphone; Respiration; Stroke Volume	2005
Quantitation of morphine, codeine, hydrocodone, hydromorphone, oxycodone, oxymorphone, and 6-monoacetylmorphine (6-MAM) in urine, blood, serum, or plasma using liquid chromatography with tandem mass spectrometry detection. Methods in molecular biology (Clifton, N.J.), 2010, Volume: 603 Topics: Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry	2010
Evaluation of the usefulness of an oxycodone immunoassay in combination with a traditional opiate immunoassay for the screening of opiates in urine. Journal of analytical toxicology, 2010, Volume: 34, Issue:2 Topics: Acetylation; Codeine; False Negative Reactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Hydrocodone; Hydromorphone; Immunoassay; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection	2010
Factors affecting acceptability of titrated oxymorphone extended release in chronic low back pain - an individual patient analysis. Current medical research and opinion, 2010, Volume: 26, Issue:8 Topics: Aged; Analgesics, Opioid; Chronic Disease; Clinical Trials, Phase III as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Low Back Pain; Male; Middle Aged; Oxycodone; Oxymorphone; Pain Measurement; Patient Acceptance of Health Care; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Treatment Outcome	2010
Quantitation of opioids in whole blood by electron impact-gas chromatography-mass spectrometry. Journal of analytical toxicology, 2011, Volume: 35, Issue:2 Topics: Analgesics, Opioid; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection	2011
Hydrophilic interaction LC-MS/MS analysis of opioids in urine: significance of glucuronide metabolites. Bioanalysis, 2011, Volume: 3, Issue:23 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Gas Chromatography-Mass Spectrometry; Glucuronides; Humans; Hydrocodone; Hydromorphone; Hydrophobic and Hydrophilic Interactions; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry	2011
Pharmacokinetics of ammonium sulfate gradient loaded liposome-encapsulated oxymorphone and hydromorphone in healthy dogs. Veterinary anaesthesia and analgesia, 2013, Volume: 40, Issue:5 Topics: Ammonium Sulfate; Analgesics, Opioid; Animals; Area Under Curve; Dogs; Half-Life; Hydromorphone; Liposomes; Male; Oxymorphone	2013
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology. Journal of analytical toxicology, 2014, Volume: 38, Issue:8 Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry	2014
LC-MS-MS Method for Analysis of Opiates in Wastewater During Football Games II. Journal of analytical toxicology, 2016, Volume: 40, Issue:5 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Football; Humans; Hydrocodone; Hydromorphone; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical	2016
Degradation of Opioids and Opiates During Acid Hydrolysis Leads to Reduced Recovery Compared to Enzymatic Hydrolysis. Journal of analytical toxicology, 2016, Volume: 40, Issue:8 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Glucuronidase; Humans; Hydrocodone; Hydrolysis; Hydromorphone; Morphine; Morphine Derivatives; Opiate Alkaloids; Oxycodone; Oxymorphone; Specimen Handling; Tandem Mass Spectrometry	2016
Suitability of the DRI Hydrocodone/Hydromorphone Immunoassay in the Clinical Environment at a Lower Cutoff: Validation With LC-MS/MS Analysis. Therapeutic drug monitoring, 2016, Volume: 38, Issue:6 Topics: Analgesics, Opioid; Chromatography, Liquid; Humans; Hydrocodone; Hydromorphone; Immunoassay; Oxycodone; Oxymorphone; Sensitivity and Specificity; Substance Abuse Detection; Tandem Mass Spectrometry	2016
Development of a Quantitative LC-MS-MS Assay for Codeine, Morphine, 6-Acetylmorphine, Hydrocodone, Hydromorphone, Oxycodone and Oxymorphone in Neat Oral Fluid. Journal of analytical toxicology, 2018, Jul-01, Volume: 42, Issue:6 Topics: Analgesics, Opioid; Calibration; Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Opioid-Related Disorders; Oxycodone; Oxymorphone; Predictive Value of Tests; Reference Standards; Reproducibility of Results; Saliva; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry	2018
Positivity rates of drugs in patients treated for opioid dependence with buprenorphine: A comparison of oral fluid and urine using paired collections and LC-MS/MS. Drug and alcohol dependence, 2018, 12-01, Volume: 193 Topics: Buprenorphine; Cannabinoids; Chromatography, Liquid; Humans; Hydrocodone; Hydromorphone; Illicit Drugs; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Oxymorphone; Retrospective Studies; Saliva; Substance Abuse Detection; Tandem Mass Spectrometry	2018
Comparative Analysis of ELISA Immunoassay and LC-QTOF for Opiate Screening. Journal of analytical toxicology, 2020, May-18, Volume: 44, Issue:4 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Enzyme-Linked Immunosorbent Assay; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection	2020
Declines and regional variation in opioid distribution by U.S. hospitals. Pain, 2022, 06-01, Volume: 163, Issue:6 Topics: Analgesics, Opioid; Buprenorphine; Codeine; Hospitals; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Oxymorphone; United States	2022
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases. Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8 Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem	2022
A preliminary study of hydrocodone and hydromorphone to oxycodone ratios for distinguishing impurities from independent opioid use. Clinical biochemistry, 2023, Volume: 112 Topics: Analgesics, Opioid; Chromatography, Liquid; Humans; Hydrocodone; Hydromorphone; Opioid-Related Disorders; Oxycodone; Oxymorphone; Tandem Mass Spectrometry	2023