hydromorphone and naloxone

hydromorphone has been researched along with naloxone in 98 studies

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199060 (61.22)18.7374
1990's10 (10.20)18.2507
2000's15 (15.31)29.6817
2010's11 (11.22)24.3611
2020's2 (2.04)2.80

Authors

AuthorsStudies
Howes, JF; Kotick, MP; Osgood, PF; Polazzi, JO; Razdan, RK; Schut, RN; Villarreal, JE1
Kotick, MP; Leland, DL1
Strassburg, CP; Tukey, RH1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Pasternak, GW; Snyder, SH; Wilson, HA2
Pollock, SH1
Pasternak, GW; Snowman, AM; Snyder, SH1
Resnick, RB; Volavka, J1
Horng, JS; Smits, SE; Wong, DT1
Abbott, J; Blosser, J; Shain, W1
Simantov, R; Snowman, AM; Snyder, SH1
Simantov, R; Snyder, SH1
Greenstein, R; O'Brien, C1
Fishman, J; Foldes, FF; Hahn, EF; Ronai, AZ1
Geisow, MJ; Smyth, DG1
Caruso, TP; Larson, DL; Portoghese, PS; Takemori, AE2
Baskerville, JC; Brands, B; Gowdey, CW; Hirst, M1
Grabowski, J; Greenstein, R; McLellan, AT; O'Brien, CP; Ternes, J1
Bigelow, GE; Liebson, IA; Preston, KL; Strain, EC3
Fudala, PJ; Johnson, RE1
Kumagai, Y; Todaka, T; Toki, S1
Bigelow, GE; Liebson, IA; Preston, KL6
Bigelow, GE; Liebson, I; Preston, KL; Strain, EC1
Angel, L; Appelmans, N; Gioannini, TL; Koolpe, GA; Nelson, WL; Simon, EJ1
Archer, S; Corbett, AD; Kosterlitz, HW; McKnight, AT; Paterson, SJ; Seyed-Mozaffari, A; Ward, S1
Goodman, RR; Hahn, EF; Nishimura, S; Pasternak, GW1
Hahn, EF; Itzhak, Y; Johnson, N; Nishimura, S; Pasternak, GW1
Randall, JI; Rodgers, RJ1
Einarsson, M; Koman, A; Terenius, L1
Ikebuchi, H; Nagamatsu, K; Ohno, Y; Takahashi, A; Takanaka, A; Terao, T1
Benyhe, S; Borsodi, A; Hosztafi, S; Toth, G; Varga, E1
Ehrman, RN; O'Brien, CP; Ternes, JW1
Larson, DL; Lemieux, C; Nguyen, TM; Portoghese, PS; Ronsisvalle, G; Schiller, PW; Takemori, AE1
Bickel, W; Bigelow, GE; Liebson, IA; Preston, KL1
Bodnar, RJ; Burks, TF; Clark, JE; Hahn, EF; Pasternak, GW; Williams, CL1
Foley, KM; Houde, RW; Inturrisi, CE; Moulin, DE; Nip, TJ; Reidenberg, B; Wallenstein, S; Weinberg, DS1
Benyhe, S; Borsodi, A; Hoffmann, G; Hosztafi, S; Toth, G; Varga, E; Wollemann, M1
Cheng, SW; North, WG; O'Connor, EF1
Copland, VS; Haskins, SC; Patz, J1
Ebertz, JM; Hanifin, JM; Hermens, JM; Hirshman, CA1
Abdelhamid, EM; Archer, S; Koolpe, GA; Michael, J; Michael, M; Nelson, WL; Simon, EJ1
Gorodetzky, CW1
Hug, CC; Vasko, MR1
Pasternak, G; Pert, CB; Snyder, SH1
Terenius, L1
Klee, WA; Streaty, RA1
Bigelow, GE; Liebson, IA; Preston, KL; Stitzer, ML1
Hahn, EF; Pasternak, GW1
Armstrong, MJ; Larson, AA1
Kanel, GC; Needham, WP; Shuster, L; Thompson, ML1
Carroll-Buatti, M; Hahn, EF; Pasternak, GW1
Ishida, T; Kido, Y; Nagamatsu, K; Terao, T; Toki, S1
Hemmer, RC; Kastin, AJ; McLean, JH; Olson, GA; Olson, RD1
Ehrman, R; O'Brien, CP; Ternes, JW1
Giles, T; Merz, H; Sander, G1
Cooper, SJ; Turkish, S1
Dashwood, MR; Kiang, JG; Wei, ET1
Jacob, JJ; Rios, L1
Galetta, S; Ling, GS; Pasternak, GW1
Angel, L; Gioannini, TL; Koolpe, GA; Nelson, WL; Simon, EJ1
Manfredi, B; Mantegazza, P; Panerai, AE; Sacerdote, P1
Borowitz, JL; Gunasekar, PG; Isom, GE1
Hameedi, FA; Kosten, TA; Kosten, TR; Oliveto, AH; Rosen, MI; Woods, SW1
Bigelow, GE; Stoller, K; Strain, EC; Walsh, SL1
Bigelow, GE; Stoller, KB; Strain, EC; Walsh, SL1
Bigelow, GE; Strain, EC; Walsh, SL1
Cohen, SP; Mao, J1
Compton, P; Elashoff, D; Miotto, K1
Ananthan, S; Bartlett, JL; Bilsky, EJ; Davis, P; Dersch, CM; Khare, NK; Porreca, F; Rothman, RB; Saini, SK; Seitz, LE1
Borowitz, JL; Gunasekar, PG; Isom, GE; Li, L; Prabhakaran, K; Zhang, L1
Bigelow, GE; Carroll, CP; Preston, KL; Strain, EC; Walsh, SL1
Hofmann, A; Lafontaine, AL; Postuma, RB; Tangri, N1
Bigelow, GE; Correia, CJ; Strain, EC; Walsh, SL1
Mushlin, N; Roberts, R; Vahid, B1
Bernstein, RA; Dubow, J1
Bigelow, GE; Correia, CJ; Duke, AN; Strain, EC; Walsh, SL1
Bigelow, GE; Lanier, RK; Lofwall, MR; Mintzer, MZ; Strain, EC1
Chang-Chien, GC; Chu, SK; Joseph, P; McCormick, Z1
Albertson, TE; Chenoweth, JA; Clarke, SO; Gutierrez, R; Roche, BM; Sutter, ME; Wintemute, GJ1
Kharasch, S; Kostic, M; Schultz, ML1
Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K1
Anis, AH; Brissette, S; Guh, D; Harrison, S; Janmohamed, A; Jutha, S; Krausz, M; MacDonald, S; Marchand, K; Marsh, DC; Oviedo-Joekes, E; Schechter, MT; Zhang, DZ1
Arthur, K; Davis, C; Fuller, J; Geik, C; Johnston, E; Leung, E; Levitt, F; McCart, G; McMichael, D; Painter, J; Staublin, T; Walroth, T1
Holland, TL; Neuss, MJ1
Baetge, CL; Coursey, CD; Lizarraga, I; Scallan, EM; Simon, BT1
Churchill, B; Root-Bernstein, R; Turke, M1
Caputo, A; Christopher, C; Compton, P; Delgado, MK; Lowenstein, M; McFadden, R; Olenik, JM; Perrone, J; Ronning, K; Sigueza, AL; Thakrar, AP; Uritsky, TJ; Winston, A1

Reviews

3 review(s) available for hydromorphone and naloxone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Review of Intranasally Administered Medications for Use in the Emergency Department.
    The Journal of emergency medicine, 2017, Volume: 53, Issue:1

    Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics

2017

Trials

16 trial(s) available for hydromorphone and naloxone

ArticleYear
Acute effects of buprenorphine, hydromorphone and naloxone in methadone-maintained volunteers.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Adult; Buprenorphine; Cognition; Drug Interactions; Hemodynamics; Humans; Hydromorphone; Injections, Intramuscular; Male; Methadone; Naloxone; Psychomotor Performance; Substance Abuse Treatment Centers; Substance-Related Disorders

1992
Development of buprenorphine for the treatment of opioid dependence.
    NIDA research monograph, 1992, Volume: 121

    Topics: Adult; Buprenorphine; Double-Blind Method; Female; Follow-Up Studies; Heroin Dependence; Humans; Hydromorphone; Male; Middle Aged; Naloxone; Substance Withdrawal Syndrome; Testosterone

1992
Buprenorphine and naloxone alone and in combination in opioid-dependent humans.
    Psychopharmacology, 1988, Volume: 94, Issue:4

    Topics: Adult; Blood Pressure; Body Temperature; Buprenorphine; Cognition; Heart Rate; Humans; Hydromorphone; Male; Naloxone; Opioid-Related Disorders; Psychomotor Performance; Respiration; Substance Withdrawal Syndrome

1988
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2

    Topics: Adult; Butorphanol; Cognition; Double-Blind Method; Humans; Hydromorphone; Injections, Intramuscular; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Psychomotor Performance; Substance Withdrawal Syndrome

1988
Antagonist effects of nalbuphine in opioid-dependent human volunteers.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Methadone; Morphinans; Nalbuphine; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome

1989
Precipitated withdrawal by pentazocine in methadone-maintained volunteers.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Adult; Behavior; Humans; Hydromorphone; Male; Methadone; Naloxone; Pentazocine; Psychomotor Performance; Substance Withdrawal Syndrome; Time Factors

1993
Opioid antagonist effects of dezocine in opioid-dependent humans.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:2

    Topics: Adult; Bridged Bicyclo Compounds, Heterocyclic; Cognition; Cycloparaffins; Humans; Hydromorphone; Male; Monitoring, Physiologic; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Psychomotor Performance; Surveys and Questionnaires; Tetrahydronaphthalenes

1996
Effects of buprenorphine versus buprenorphine/naloxone tablets in non-dependent opioid abusers.
    Psychopharmacology, 2000, Volume: 148, Issue:4

    Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Buprenorphine; Drug Combinations; Humans; Hydromorphone; Injections, Intravenous; Male; Middle Aged; Motor Activity; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Tablets; Time Factors

2000
Effects of buprenorphine/naloxone in opioid-dependent humans.
    Psychopharmacology, 2001, Volume: 154, Issue:3

    Topics: Administration, Sublingual; Adolescent; Adult; Affect; Buprenorphine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydromorphone; Injections, Intramuscular; Male; Middle Aged; Naloxone; Narcotic Antagonists; Narcotics; Observer Variation; Opioid-Related Disorders; Psychomotor Performance; Substance Withdrawal Syndrome

2001
Blockade of hydromorphone effects by buprenorphine/naloxone and buprenorphine.
    Psychopharmacology, 2002, Volume: 159, Issue:2

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydromorphone; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders

2002
Precipitated opioid withdrawal across acute physical dependence induction methods.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:2

    Topics: Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Heart Rate; Humans; Hydromorphone; Injections, Intramuscular; Injections, Intravenous; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pupil; Respiratory Mechanics; Substance Withdrawal Syndrome; Substance-Related Disorders

2004
Effects associated with double-blind omission of buprenorphine/naloxone over a 98-h period.
    Psychopharmacology, 2006, Volume: 189, Issue:3

    Topics: Adult; Analgesics, Opioid; Buprenorphine; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydromorphone; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome

2006
Acute effects of intramuscular and sublingual buprenorphine and buprenorphine/naloxone in non-dependent opioid abusers.
    Psychopharmacology, 2010, Volume: 211, Issue:3

    Topics: Administration, Sublingual; Adult; Buprenorphine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Users; Female; Humans; Hydromorphone; Injections, Intramuscular; Male; Middle Aged; Naloxone; Opioid-Related Disorders; Surveys and Questionnaires

2010
Physical dependence potential of daily tramadol dosing in humans.
    Psychopharmacology, 2010, Volume: 211, Issue:4

    Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydromorphone; Male; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; Tramadol

2010
Safety profile of injectable hydromorphone and diacetylmorphine for long-term severe opioid use disorder.
    Drug and alcohol dependence, 2017, 07-01, Volume: 176

    Topics: Adult; Analgesics, Opioid; Canada; Double-Blind Method; Drug Overdose; Female; Heroin; Heroin Dependence; Humans; Hydromorphone; Injections; Male; Middle Aged; Naloxone; Opioid-Related Disorders; Self Administration; Severity of Illness Index; Time Factors

2017
The antinociceptive effects of intravenous administration of three doses of butorphanol tartrate or naloxone hydrochloride following hydromorphone hydrochloride to healthy conscious cats.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:4

    Topics: Administration, Intravenous; Analgesics, Opioid; Animals; Butorphanol; Cats; Cross-Over Studies; Drug Therapy, Combination; Female; Hydromorphone; Naloxone; Pain; Pain Measurement; Random Allocation; Skin Temperature

2019

Other Studies

79 other study(ies) available for hydromorphone and naloxone

ArticleYear
Analgesic narcotic antagonists. 2. 8-Alkymorphinan-6-ones.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:2

    Topics: Acetates; Analgesics; Animals; Haplorhini; Humans; Mice; Morphinans; Morphine Dependence; Narcotic Antagonists; Rats; Reaction Time; Structure-Activity Relationship; Substance Withdrawal Syndrome; Substance-Related Disorders

1980
Analgesic narcotic antagonists. 4. 7-Methyl-N-(cycloalkylmethyl)-3-hydroxymorphinan-6-ones and -isomorphinan-6-ones.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:12

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Humans; Morphinans; Morphine Dependence; Narcotic Antagonists; Substance Withdrawal Syndrome

1980
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Differentiation of opiate agonist and antagonist receptor binding by protein modifying reagents.
    Nature, 1975, Feb-06, Volume: 253, Issue:5491

    Topics: Animals; Binding Sites; Brain; Chloromercuribenzoates; Ethylmaleimide; Hydromorphone; In Vitro Techniques; Iodoacetates; Levallorphan; Levorphanol; Naloxone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Receptors, Drug; Structure-Activity Relationship; Sulfhydryl Reagents; Tritium

1975
Differential effects of protein-modifying reagents on receptor binding of opiate agonists and antagonists.
    Molecular pharmacology, 1975, Volume: 11, Issue:3

    Topics: Animals; Binding Sites; Hydromorphone; In Vitro Techniques; Iodoacetamide; Male; Mercury; Naloxone; Narcotic Antagonists; Organometallic Compounds; Rats; Receptors, Drug; Sodium; Sulfhydryl Reagents; Temperature

1975
Dihydromorphinine ketone reductases.
    Life sciences, 1975, Aug-01, Volume: 17, Issue:3

    Topics: Alcohol Oxidoreductases; Animals; Chickens; Cytosol; Hydromorphone; Ketamine; Liver; Molecular Weight; Morphine; NADH, NADPH Oxidoreductases; Naloxone; Rabbits; Species Specificity; Structure-Activity Relationship

1975
Selective enhancement of [3H]opiate agonist binding by divalent cations.
    Molecular pharmacology, 1975, Volume: 11, Issue:6

    Topics: Animals; Brain; Cations, Divalent; Chelating Agents; Hydromorphone; Magnesium; Male; Manganese; Morphine Derivatives; Naloxone; Narcotic Antagonists; Rats; Receptors, Drug; Sodium

1975
Letter: Treatment of accidental naltrexone-induced withdrawal.
    The American journal of psychiatry, 1976, Volume: 133, Issue:2

    Topics: Adult; Humans; Hydromorphone; Male; Methadone; Naloxone; Naltrexone; Substance Withdrawal Syndrome

1976
The binding of the optical isomers of methadone, alpha-methadol, alpha-acetylmethadol and their N-demethylated derivatives to the opiate receptors of rat brain.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 14, Issue:4

    Topics: Animals; Brain; Dealkylation; Hydromorphone; In Vitro Techniques; Isomerism; Methadone; Methadyl Acetate; Naloxone; Rats; Receptors, Drug

1976
Sympathetic ganglion cell C neuroblastoma hybrids with opiate receptors.
    Biochemical pharmacology, 1976, Nov-01, Volume: 25, Issue:21

    Topics: Animals; Binding, Competitive; Cell Line; Ganglia, Spinal; Hydromorphone; Mice; Morphine Derivatives; Naloxone; Neuroblastoma; Receptors, Opioid

1976
Temperature and ionic influences on opiate receptor binding.
    Molecular pharmacology, 1976, Volume: 12, Issue:6

    Topics: Animals; Antimetabolites; Brain; Calcium; Cations, Divalent; Cations, Monovalent; Cesium; Hydromorphone; In Vitro Techniques; Lithium; Magnesium; Male; Manganese; Naloxone; Rats; Receptors, Opioid; Sodium; Temperature

1976
Morphine-like peptides, leucine enkephalin and methionine enkephalin: interactions with the opiate receptor.
    Molecular pharmacology, 1976, Volume: 12, Issue:6

    Topics: Animals; Bacitracin; Binding, Competitive; Cations, Divalent; Cations, Monovalent; Hydromorphone; In Vitro Techniques; Kinetics; Naloxone; Oligopeptides; Rats; Receptors, Opioid; Serum Albumin, Bovine; Temperature; Time Factors

1976
Naltrexone in a behavioral treatment program.
    NIDA research monograph, 1976, Issue:9

    Topics: Behavior; Conditioning, Psychological; Extinction, Psychological; Humans; Hydromorphone; Injections; Naloxone; Naltrexone; Remission, Spontaneous; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1976
Orientation of the oxygen atom at C-6 as a determinant of agonistic activity in the oxymorphone series.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:3

    Topics: Animals; Guinea Pigs; Hydromorphone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oxygen; Oxymorphone; Structure-Activity Relationship

1977
Preparation and properties of lipotropin C-fragment with anionic substituents attached to the lysine residues.
    FEBS letters, 1977, Sep-15, Volume: 81, Issue:2

    Topics: Animals; beta-Lipotropin; Binding, Competitive; Brain; Hydromorphone; Lysine; Naloxone; Peptide Fragments; Rats; Receptors, Opioid

1977
Chloroxymorphamine, and opioid receptor site-directed alkylating agent having narcotic agonist activity.
    Science (New York, N.Y.), 1979, Apr-20, Volume: 204, Issue:4390

    Topics: Alkylating Agents; Animals; Chlorambucil; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Hydromorphone; In Vitro Techniques; Morphine; Naloxone; Naltrexone; Nitrogen Mustard Compounds; Norepinephrine; Oxymorphone; Phenoxybenzamine; Receptors, Opioid

1979
Dependence in rats after one injection of heroin-, LAAM- or hydromorphone-zinc tannate.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Heroin; Heroin Dependence; Humans; Hydromorphone; Methadone; Methadyl Acetate; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1979
Unreinforced self-injections: effects on rituals and outcome in heroin addicts.
    NIDA research monograph, 1979, Volume: 27

    Topics: Extinction, Psychological; Follow-Up Studies; Heroin Dependence; Humans; Hydromorphone; Male; Naloxone; Naltrexone; Reinforcement, Psychology; Research Design; Self Administration

1979
A new metabolic pathway of morphine: in vivo and in vitro formation of morphinone and morphine-glutathione adduct in guinea pig.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Bile; Glutathione; Guinea Pigs; Hydromorphone; In Vitro Techniques; Lithocholic Acid; Liver; Male; Morphine; Naloxone

1990
Discrimination of butorphanol and nalbuphine in opioid-dependent humans.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3

    Topics: Adult; Behavior; Blood Pressure; Body Temperature; Butorphanol; Discrimination, Psychological; Generalization, Psychological; Humans; Hydromorphone; Male; Methadone; Middle Aged; Nalbuphine; Naloxone; Psychomotor Performance; Pupil; Receptors, Opioid

1990
The effects of buprenorphine in methadone-dependent volunteers.
    NIDA research monograph, 1990, Volume: 105

    Topics: Buprenorphine; Double-Blind Method; Humans; Hydromorphone; Male; Methadone; Naloxone; Opioid-Related Disorders; Pupil

1990
Opioid agonists and antagonists. 6-Desoxy-6-substituted lactone, epoxide, and glycidate ester derivatives of naltrexone and oxymorphone.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Circular Dichroism; Epoxy Compounds; Ethers, Cyclic; Hydromorphone; Lactones; Male; Naloxone; Naltrexone; Oxymorphone; Propionates; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship

1985
10-Ketonaltrexone and 10-ketooxymorphone.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Animals; Biological Assay; Brain; Chemical Phenomena; Chemistry; Guinea Pigs; Hydromorphone; Ileum; Male; Mice; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens

1985
Irreversible opiate agonists and antagonists. II. Evidence against a bivalent mechanism of action for opiate azines and diacylhydrazones.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Animals; Binding, Competitive; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship

1985
Irreversible opiate agonists and antagonists. III. Phenylhydrazone derivatives of naloxone and oxymorphone.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Albumins; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship; Tritium

1985
Social conflict analgesia: studies on naloxone antagonism and morphine cross-tolerance in male DBA/2 mice.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:5

    Topics: Analgesia; Animals; Conflict, Psychological; Drug Tolerance; Hydromorphone; Male; Mice; Mice, Inbred DBA; Morphine; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Oxymorphone

1985
Agonist-antagonist properties of fluorescent opioid probes in the guinea-pig myenteric plexus-longitudinal muscle preparation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:4

    Topics: Animals; Chemical Phenomena; Chemistry; Depression, Chemical; Fluorescent Dyes; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Male; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Stereoisomerism; Stimulation, Chemical

1985
Morphine metabolism in isolated rat hepatocytes and its implications for hepatotoxicity.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: Animals; Cell Survival; Glutathione; Hydromorphone; Isoenzymes; L-Lactate Dehydrogenase; Liver; Male; Morphine; Morphine Derivatives; Naloxone; Perfusion; Rats; Rats, Inbred Strains

1986
Synthesis and binding of 3H-oxymorphazone to rat brain membranes.
    Life sciences, 1987, Apr-20, Volume: 40, Issue:16

    Topics: Animals; Binding, Competitive; Brain; Hydromorphone; In Vitro Techniques; Isotope Labeling; Kinetics; Naloxone; Oxymorphone; Radioligand Assay; Rats; Receptors, Opioid; Tritium

1987
Nondependent monkeys self-administer hydromorphone.
    Behavioral neuroscience, 1985, Volume: 99, Issue:3

    Topics: Animals; Cocaine; Drug Tolerance; Hydromorphone; Macaca; Macaca fascicularis; Macaca mulatta; Naloxone; Opioid-Related Disorders; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders

1985
Hybrid bivalent ligands with opiate and enkephalin pharmacophores.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: Analgesics; Animals; Enkephalins; Guinea Pigs; Hydromorphone; Ligands; Male; Mice; Muscle, Smooth; Naloxone; Oxymorphone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1987
Three-choice drug discrimination in opioid-dependent humans: hydromorphone, naloxone and saline.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3

    Topics: Adult; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Psychological; Humans; Hydromorphone; Male; Methadone; Naloxone; Opioid-Related Disorders; Psychomotor Performance

1987
Abuse liability assessment of buprenorphine-naloxone combinations.
    NIDA research monograph, 1987, Volume: 76

    Topics: Blood Pressure; Buprenorphine; Drug Combinations; Heart Rate; Humans; Hydromorphone; Male; Naloxone; Pupil; Respiration; Skin Temperature; Substance-Related Disorders; Surveys and Questionnaires

1987
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
    NIDA research monograph, 1987, Volume: 76

    Topics: Butorphanol; Heart Rate; Humans; Hydromorphone; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Pupil; Respiration; Skin Temperature; Substance Withdrawal Syndrome; Surveys and Questionnaires

1987
Irreversible opiate agonists and antagonists. IV. Analgesic actions of 14-hydroxydihydromorphinone hydrazones.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; Male; Mice; Naloxone; Oxymorphone; Receptors, Opioid; Time Factors

1988
Sublingual absorption of selected opioid analgesics.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Analysis of Variance; Biological Availability; Buprenorphine; Fentanyl; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Mouth; Naloxone; Oxycodone; Time Factors

1988
Effects of oxymorphazone in frogs: long lasting antinociception in vivo, and apparently irreversible binding in vitro.
    Life sciences, 1989, Volume: 44, Issue:24

    Topics: Analgesics; Animals; Binding, Competitive; Brain; Cell Membrane; Dose-Response Relationship, Drug; Hydromorphone; Kinetics; Naloxone; Oxymorphone; Rana esculenta; Receptors, Opioid; Spinal Cord

1989
Simultaneous extraction and chromatographic analysis of morphine, dilaudid, naltrexone and naloxone in biological fluids by high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1989, Jun-30, Volume: 491, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Hydromorphone; Male; Morphine; Naloxone; Naltrexone; Rats

1989
Naloxone reversal of oxymorphone effects in dogs.
    American journal of veterinary research, 1989, Volume: 50, Issue:11

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; Heart; Heart Rate; Hydromorphone; Naloxone; Oxygen; Oxymorphone; Pulmonary Wedge Pressure; Respiration; Tidal Volume; Vascular Resistance

1989
Comparison of histamine release in human skin mast cells induced by morphine, fentanyl, and oxymorphone.
    Anesthesiology, 1985, Volume: 62, Issue:2

    Topics: Cell Membrane; Dose-Response Relationship, Drug; Fentanyl; Histamine; Histamine Release; Humans; Hydromorphone; Leukocytes; Mast Cells; Morphine; Naloxone; Oxymorphone; Receptors, Opioid; Skin

1985
Chloroacryloyl amides and alpha-methylenelactones from naltrexone, oxymorphone and fentanyl.
    Neuropeptides, 1985, Volume: 5, Issue:4-6

    Topics: Acrylates; Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Fentanyl; Hydromorphone; In Vitro Techniques; Membranes; Naloxone; Naltrexone; Oxymorphone; Rats; Stereoisomerism

1985
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
Is the uptake of narcotic analgesics by cerebral cortical slices mediated in part by active transport?
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:2

    Topics: Anaerobiosis; Analgesics; Animals; Antimetabolites; Biological Transport, Active; Cerebral Cortex; Hydromorphone; Male; Nalorphine; Naloxone; Rats; Tritium

1973
Opiate agonists and antagonists discriminated by receptor binding in brain.
    Science (New York, N.Y.), 1973, Dec-28, Volume: 182, Issue:4119

    Topics: Analgesics; Animals; Binding, Competitive; Brain; Hydromorphone; In Vitro Techniques; Levallorphan; Levorphanol; Mice; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Oxymorphone; Receptors, Drug; Sodium; Tritium

1973
Stereospecific uptake of narcotic analgesics by a subcellular fraction of the guinea-pig ileum. A preliminary communication.
    Upsala journal of medical sciences, 1973, Volume: 78, Issue:3

    Topics: Analgesics; Animals; Codeine; Dextromoramide; Female; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Intestinal Absorption; Levorphanol; Male; Methadone; Morphine; Muscle, Smooth; Nalorphine; Naloxone; Narcotics; Subcellular Fractions; Tritium

1973
Narcotic receptor sites in morphine-dependent rats.
    Nature, 1974, Mar-01, Volume: 248, Issue:5443

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Drug Tolerance; Female; Humans; Hydromorphone; In Vitro Techniques; Male; Morphinans; Morphine; Morphine Dependence; Naloxone; Physostigmine; Rats; Receptors, Drug; Tritium

1974
Three-choice discrimination in methadone maintenance patients: hydromorphone, naloxone, and saline.
    NIDA research monograph, 1984, Volume: 55

    Topics: Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Methadone; Naloxone; Substance-Related Disorders

1984
Long-acting opiate agonists and antagonists: 14-hydroxydihydromorphinone hydrazones.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Analgesics, Opioid; Animals; Brain; Delayed-Action Preparations; Hydrazones; Hydromorphone; In Vitro Techniques; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oxymorphone; Rats; Receptors, Opioid

1980
Morphine analgesia after intrathecal administration of a narcotic agonist, chloroxymorphamine and antagonist, chlornaltrexamine.
    European journal of pharmacology, 1980, Nov-07, Volume: 68, Issue:1

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Hydromorphone; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nitrogen Mustard Compounds; Oxymorphone; Rats

1980
Pharmacological studies with an alkylating narcotic agonist, chloroxymorphamine, and antagonist, chlornaltrexamine.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:3

    Topics: Analgesics; Animals; Brain; Hydromorphone; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nitrogen Mustard Compounds; Oxymorphone

1980
Liver damage from narcotics in mice.
    Toxicology and applied pharmacology, 1981, Volume: 58, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cytochrome P-450 Enzyme System; Drug Tolerance; Female; Hydromorphone; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Naloxone; Narcotics; Sex Factors; Species Specificity

1981
Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1982, Volume: 2, Issue:5

    Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Drug Stability; Hydromorphone; Kinetics; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship

1982
Effect of morphinone on opiate receptor binding and morphine-elicited analgesia.
    Life sciences, 1982, Oct-04, Volume: 31, Issue:14

    Topics: Analgesia; Animals; Cysteine; Dihydromorphine; Glutathione; Hydromorphone; Kinetics; Mice; Morphine; Naloxone; Receptors, Opioid

1982
Effects of naloxone and its quaternary form on fluid consumption in rats.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Drinking; Hydromorphone; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Oxymorphone; Rats; Rats, Inbred Strains

1982
Cynomolgus monkeys do not develop tolerance to opioids.
    Behavioral neuroscience, 1983, Volume: 97, Issue:2

    Topics: Animals; Drug Tolerance; Humans; Hydromorphone; Macaca fascicularis; Macaca mulatta; Naloxone; Opioid-Related Disorders; Species Specificity

1983
Quaternary opiate antagonists lower blood pressure and inhibit leucine-enkephalin responses.
    European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4

    Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Enkephalin, Leucine; Heart Rate; Hydromorphone; Naloxone; Naltrexone; Oxymorphone; Quaternary Ammonium Compounds

1983
Fluid consumption in water-deprived rats after administration of naloxone or quaternary naloxone.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6

    Topics: Animals; Drinking; Hydromorphone; Male; Muridae; Naloxone; Oxymorphone; Receptors, Opioid; Taste; Thirst; Water Deprivation

1983
An etorphine-evoked vagal reflex in rats is inhibited by naloxone, N-methylnaloxone, and SMS 201-995.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 266, Issue:1

    Topics: Animals; Blood Pressure; Etorphine; Heart Rate; Hydromorphone; Male; Morphinans; Naloxone; Octreotide; Oxymorphone; Rats; Rats, Inbred Strains; Reflex; Respiration; Somatostatin; Vagus Nerve

1983
Local inhibition of inflammatory pain by naloxone and its N-methyl quaternary analogue.
    European journal of pharmacology, 1983, Dec-23, Volume: 96, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Foot; Hydromorphone; Injections, Subcutaneous; Male; Morphine; Naloxone; Nociceptors; Oxymorphone; Rats; Rats, Inbred Strains

1983
Oxymorphazone: a long-acting opiate analgesic.
    Cellular and molecular neurobiology, 1984, Volume: 4, Issue:1

    Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Methionine; Hydromorphone; Injections, Intraventricular; Morphine; Naloxone; Oxymorphone; Rats; Receptors, Opioid; Time Factors

1984
Diastereomeric 6-desoxy-6-spiro-alpha-methylene-gamma-butyrolactone derivatives of naltrexone and oxymorphone. Selective irreversible inhibition of naltrexone binding in an opioid receptor preparation by a conformationally restricted michael acceptor liga
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Brain; Cell Membrane; Chromatography, Thin Layer; Hydromorphone; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Conformation; Naloxone; Naltrexone; Narcotic Antagonists; Optical Rotation; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship

1984
Antinociceptive and immunosuppressive effects of opiate drugs: a structure-related activity study.
    British journal of pharmacology, 1997, Volume: 121, Issue:4

    Topics: Animals; Cell Division; Codeine; Hydromorphone; Immune System; Immunosuppression Therapy; Interleukin-2; Male; Mice; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotics; Oxycodone; Structure-Activity Relationship

1997
Hydrogen cyanide generation by mu-opiate receptor activation: possible neuromodulatory role of endogenous cyanide.
    Brain research, 1997, Sep-12, Volume: 768, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Cells, Cultured; Cricetinae; Female; Hydrogen Cyanide; Hydromorphone; In Vitro Techniques; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurons; Neurotransmitter Agents; PC12 Cells; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1997
Hydromorphone-naloxone combinations in opioid-dependent humans under a naloxone novel-response discrimination procedure.
    Experimental and clinical psychopharmacology, 1998, Volume: 6, Issue:2

    Topics: Adult; Discrimination Learning; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Male; Methadone; Naloxone; Opioid-Related Disorders

1998
Is the analgesic effect of systemic lidocaine mediated through opioid receptors?
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:7

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Drug Interactions; Female; Humans; Hydromorphone; Infusions, Intravenous; Lidocaine; Middle Aged; Naloxone; Narcotic Antagonists

2003
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Analgesics; Animals; Binding Sites; Brain; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Oxymorphone; Pyridines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens

2004
Receptor mechanisms mediating cyanide generation in PC12 cells and rat brain.
    Neuroscience research, 2004, Volume: 49, Issue:1

    Topics: Analysis of Variance; Animals; Atropine; Brain; Carbachol; Cells, Cultured; Cholinergic Agonists; Cyanides; Drug Interactions; Embryo, Mammalian; Hydromorphone; Morphine; Muscarinic Agonists; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Narcotics; Oxotremorine; PC12 Cells; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface

2004
Assessment of agonist and antagonist effects of tramadol in opioid-dependent humans.
    Experimental and clinical psychopharmacology, 2006, Volume: 14, Issue:2

    Topics: Adult; Analgesics, Opioid; Heart Rate; Humans; Hydromorphone; Middle Aged; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Tramadol

2006
Myoclonus as an acute complication of low-dose hydromorphone in multiple system atrophy.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:8

    Topics: Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Multiple System Atrophy; Myoclonus; Naloxone; Narcotic Antagonists

2006
Use of naloxone in hydromorphone-induced anaphylactoid reaction.
    Southern medical journal, 2007, Volume: 100, Issue:6

    Topics: Aged; Analgesics, Opioid; Anaphylaxis; Drug Hypersensitivity; Female; Humans; Hydromorphone; Naloxone

2007
Amplification of acute focal ischemic deficit by narcotics.
    Neurocritical care, 2008, Volume: 8, Issue:3

    Topics: Acute Disease; Aged; Brain Ischemia; Female; Humans; Hydrocodone; Hydromorphone; Male; Naloxone; Narcotic Antagonists; Narcotics; Pain, Postoperative

2008
Acute pain control challenges with buprenorphine/naloxone therapy in a patient with compartment syndrome secondary to McArdle's disease: a case report and review.
    Pain medicine (Malden, Mass.), 2013, Volume: 14, Issue:8

    Topics: Acetaminophen; Acute Pain; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Compartment Syndromes; Creatine Kinase; Drug Combinations; Glycogen Storage Disease Type V; Humans; Hydromorphone; Injections, Intramuscular; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Pain Measurement; Rhabdomyolysis

2013
The Changing Use of Intravenous Opioids in an Emergency Department.
    The western journal of emergency medicine, 2015, Volume: 16, Issue:7

    Topics: Adult; Analgesics, Opioid; Drug Utilization; Emergency Service, Hospital; Emergency Treatment; Female; Fentanyl; Humans; Hydromorphone; Infusions, Intravenous; Male; Middle Aged; Morphine; Naloxone; Retrospective Studies; Trauma Centers

2015
A Case of Toxic Breast-feeding?
    Pediatric emergency care, 2019, Volume: 35, Issue:1

    Topics: Analgesics, Opioid; Breast Feeding; Humans; Hydromorphone; Infant, Newborn; Milk, Human; Mothers; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Postpartum Period

2019
A Multisite Retrospective Study Evaluating the Implementation of the Pasero Opioid-Induced Sedation Scale (POSS) and Its Effect on Patient Safety Outcomes.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2017, Volume: 18, Issue:4

    Topics: Adult; Aged; Female; Humans; Hydromorphone; Hypnotics and Sedatives; Male; Middle Aged; Naloxone; Narcotic Antagonists; Outcome Assessment, Health Care; Pain Management; Patient Safety; Respiratory Insufficiency; Retrospective Studies

2017
Digital ischaemia after intra-arterial drug injection.
    BMJ case reports, 2017, Sep-25, Volume: 2017

    Topics: Buprenorphine; Constriction, Pathologic; Fingers; Humans; Hydromorphone; Injections, Intra-Arterial; Ischemia; Male; Middle Aged; Naloxone; Opiate Substitution Treatment; Opioid-Related Disorders; Peripheral Vascular Diseases; Toes

2017
Glutathione and Glutathione-Like Sequences of Opioid and Aminergic Receptors Bind Ascorbic Acid, Adrenergic and Opioid Drugs Mediating Antioxidant Function: Relevance for Anesthesia and Abuse.
    International journal of molecular sciences, 2020, Aug-28, Volume: 21, Issue:17

    Topics: Analgesics, Opioid; Ascorbic Acid; Dehydroascorbic Acid; Enkephalin, Methionine; Glutathione; Humans; Hydromorphone; Methadone; Morphine; Naloxone; Peptides; Receptors, Adrenergic, beta-2; Receptors, Dopamine D1; Receptors, Histamine H1; Receptors, Opioid; Receptors, Opioid, mu

2020
Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder.
    Addiction science & clinical practice, 2023, 02-24, Volume: 18, Issue:1

    Topics: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Female; Humans; Hydromorphone; Male; Methadone; Naloxone; Opiate Substitution Treatment; Opioid-Related Disorders; Pain

2023