hydromorphone and nalbuphine

hydromorphone has been researched along with nalbuphine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19906 (27.27)18.7374
1990's5 (22.73)18.2507
2000's5 (22.73)29.6817
2010's5 (22.73)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Bidlack, JM; Bu, Y; Cohen, DJ; Denhardt, C; Ganorkar, R; Guo, C; Jin, J; Lou, R; Lu, Q; VanAlstine, MA; Wentland, MP1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Pegelow, CH1
Bigelow, GE; Liebson, IA; Preston, KL2
Cohen, H; Henderson, SK1
Fanelli, RJ; Jasinski, DR; London, ED; Szikszay, M1
Fanelli, R; Jasinski, D; London, E; Szikszay, M1
Bickel, WK; Bigelow, GE; Liebson, IA; Preston, KL1
Blake, JW; Combie, J; Nugent, TE; Tobin, T1
Bigelow, GE; Preston, KL1
Holtmann, B; Parker, RK; White, PF1
Bigelow, GE; Jones, HE; Preston, KL1
Hosztafi, S; Kraszni, M; Mazák, K; Noszál, B1
Behm, B; Davis, MP; Fernandez, C; McPherson, ML; Mehta, Z1
Adaramola, D; Ibrahim, AM; Obaidi, Z; Onguti, S; Ruan, G1
Chen, XZ; Huang, CY; Li, SX; Xu, LL; Yang, MJ1

Reviews

3 review(s) available for hydromorphone and nalbuphine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
What Parenteral Opioids to Use in Face of Shortages of Morphine, Hydromorphone, and Fentanyl.
    The American journal of hospice & palliative care, 2018, Volume: 35, Issue:8

    Topics: Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Hydromorphone; Morphine; Nalbuphine; Pain

2018

Trials

3 trial(s) available for hydromorphone and nalbuphine

ArticleYear
Antagonist effects of nalbuphine in opioid-dependent human volunteers.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Methadone; Morphinans; Nalbuphine; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome

1989
Patient-controlled epidural analgesia: interactions between nalbuphine and hydromorphone.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Nalbuphine; Pregnancy

1997
A comparative study of three concentrations of intravenous nalbuphine combined with hydromorphone for post-cesarean delivery analgesia.
    Chinese medical journal, 2020, Mar-05, Volume: 133, Issue:5

    Topics: Adult; Analgesia, Patient-Controlled; Cesarean Section; Female; Humans; Hydromorphone; Nalbuphine; Pain, Postoperative; Patient Satisfaction; Pregnancy; Visual Analog Scale

2020

Other Studies

16 other study(ies) available for hydromorphone and nalbuphine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Syntheses of novel high affinity ligands for opioid receptors.
    Bioorganic & medicinal chemistry letters, 2009, Apr-15, Volume: 19, Issue:8

    Topics: Analgesics, Opioid; Crystallography, X-Ray; Furans; Humans; Ligands; Naltrexone; Narcotic Antagonists; Protein Binding; Receptors, Opioid

2009
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Survey of pain management therapy provided for children with sickle cell disease.
    Clinical pediatrics, 1992, Volume: 31, Issue:4

    Topics: Acetaminophen; Analgesics; Anemia, Sickle Cell; Child; Child, Preschool; Codeine; Drug Administration Schedule; Drug Combinations; Humans; Hydromorphone; Infant; Length of Stay; Meperidine; Morphine; Nalbuphine; Pain; Pain Management; Seizures

1992
Discrimination of butorphanol and nalbuphine in opioid-dependent humans.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3

    Topics: Adult; Behavior; Blood Pressure; Body Temperature; Butorphanol; Discrimination, Psychological; Generalization, Psychological; Humans; Hydromorphone; Male; Methadone; Middle Aged; Nalbuphine; Naloxone; Psychomotor Performance; Pupil; Receptors, Opioid

1990
Nalbuphine augmentation of analgesia and reversal of side effects following epidural hydromorphone.
    Anesthesiology, 1986, Volume: 65, Issue:2

    Topics: Adult; Analgesia; Anesthesia, Epidural; Cesarean Section; Female; Humans; Hydromorphone; Morphinans; Nalbuphine; Pruritus

1986
Differential effects of mu and kappa opioid analgesics on cerebral glucose utilization in the rat.
    Brain research, 1987, Oct-06, Volume: 422, Issue:2

    Topics: Animals; Autoradiography; Blood Pressure; Brain; Carbon Dioxide; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; Heart Rate; Hydromorphone; Male; Morphinans; Morphine; Nalbuphine; Organ Specificity; Oxygen; Oxymorphone; Rats; Rats, Inbred F344; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1987
Effects of opioid analgesics on local cerebral glucose utilization.
    NIDA research monograph, 1986, Volume: 75

    Topics: Animals; Brain; Deoxy Sugars; Deoxyglucose; Hydromorphone; Male; Morphinans; Morphine; Nalbuphine; Organ Specificity; Oxymorphone; Rats; Rats, Inbred F344

1986
Drug discrimination in human postaddicts: agonist-antagonist opioids.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Adult; Buprenorphine; Butorphanol; Conditioning, Operant; Discrimination, Psychological; Humans; Hydromorphone; Male; Nalbuphine; Pentazocine; Pupil; Substance-Related Disorders

1989
Furosemide, Patella vulgata beta-glucuronidase and drug analysis: conditions for enhancement of the TLC detection of apomorphine, butorphanol, hydromorphone, nalbuphine, oxymorphone and pentazocine in equine urine.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 35, Issue:1

    Topics: Animals; Apomorphine; Butorphanol; Cattle; Chromatography, Thin Layer; Female; Furosemide; Glucuronidase; Helix, Snails; Horses; Hydrolysis; Hydromorphone; Mollusca; Nalbuphine; Oxymorphone; Pentazocine; Species Specificity

1982
Drug discrimination assessment of agonist-antagonist opioids in humans: a three-choice saline-hydromorphone-butorphanol procedure.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1

    Topics: Adult; Buprenorphine; Butorphanol; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Psychological; Humans; Hydromorphone; Male; Nalbuphine; Pentazocine; Psychomotor Performance

1994
Assessment of opioid partial agonist activity with a three-choice hydromorphone dose-discrimination procedure.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Adult; Blood Pressure; Buprenorphine; Butorphanol; Choice Behavior; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Hydromorphone; Injections, Intramuscular; Male; Nalbuphine; Pentazocine; Psychomotor Performance; Surveys and Questionnaires

1999
Physico-chemical profiling of semisynthetic opioids.
    Journal of pharmaceutical and biomedical analysis, 2017, Feb-20, Volume: 135

    Topics: Analgesics, Opioid; Chemical Phenomena; Dihydromorphine; Hydromorphone; Nalbuphine; Nalorphine

2017
Nalbuphine for Opioid-Induced Urine Retention.
    Annals of internal medicine, 2018, 12-18, Volume: 169, Issue:12

    Topics: Abdominal Pain; Analgesics, Opioid; Cancer Pain; Carcinoma, Renal Cell; Hospice Care; Humans; Hydromorphone; Kidney Neoplasms; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nalbuphine; Portal Vein; Urinary Retention; Venous Thrombosis

2018