hydromorphone has been researched along with morphinone in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Archer, S; Bidlack, JM; Jiang, Q; Seyed-Mozaffari, A | 1 |
| Ikeda, Y; Kumagai, Y; Toki, S | 1 |
| Archer, S; Bidlack, JM; Frey, DK; Kaplan, RA; Seyed-Mozaffari, A | 1 |
| Kumagai, Y; Todaka, T; Toki, S | 1 |
| Bruce, NC; Gray Stephens, LD; Jordan, KN; Lowe, CR; Trebilcock, AE; Wilmot, CJ | 1 |
| Ikebuchi, H; Nagamatsu, K; Ohno, Y; Takahashi, A; Takanaka, A; Terao, T | 1 |
| Ishida, T; Kumagai, Y; Toki, S | 1 |
| Ishida, T; Kageura, E; Toki, S; Yamano, S | 1 |
| Ishida, T; Kido, Y; Nagamatsu, K; Terao, T; Toki, S | 1 |
| Fang, S; Portoghese, PS; Takemori, AE | 1 |
| Archer, S; Bidlack, JM; Deecher, D; Glick, SD; Jiang, Q; Sebastian, A; Teitler, M | 1 |
| Ito, K; Ogata, S; Toki, S; Yamano, S | 1 |
| Takahashi, A; Todaka, T; Toki, S; Yamano, S | 1 |
| Toki, S; Yamano, S | 1 |
| Bruce, NC; French, CE; Rathbone, DA; Walker, EH | 1 |
| EDDY, NB; LEE, LE | 1 |
| Asai, T; Hidaka, I; Kawachi, S; Kubota, T; Miki, T | 1 |
| Ishida, T; Kita, H; Narimatsu, S; Todaka, T; Yamano, S | 1 |
| Carroll, PJ; Dalton, DR; Wilson, ML | 1 |
| Churchill, B; Root-Bernstein, R; Turke, M | 1 |
| Kumagai, Y | 1 |
1 review(s) available for hydromorphone and morphinone
| Article | Year |
|---|---|
[Production of morphinone as a metabolite of morphine and its physiological role].
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Analgesics, Opioid; Animals; Cricetinae; Glutathione; Hydromorphone; Liver; Mice; Molecular Sequence Data; Morphine; Protein Binding; Rabbits | 1999 |
1 trial(s) available for hydromorphone and morphinone
| Article | Year |
|---|---|
[Combined use of intrathecal morphine and diclofenac suppository for postoperative analgesia after caesarean section].
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Diclofenac; Drug Therapy, Combination; Female; Humans; Hydromorphone; Injections, Spinal; Pain, Postoperative; Pregnancy; Suppositories | 2003 |
19 other study(ies) available for hydromorphone and morphinone
| Article | Year |
|---|---|
Antinociceptive properties of two alkylating derivatives of morphinone: 14 beta-(thioglycolamido)-7,8-dihydromorphinone (TAMO) and 14 beta-(bromoacetamido)-7,8-dihydromorphinone (H2BAMO).
Topics: Analgesics; Animals; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydromorphone; Male; Mice; Mice, Inbred ICR; Opioid-Related Disorders; Receptors, Opioid; Receptors, Opioid, mu | 1992 |
Hydroxyl radical-mediated conversion of morphine to morphinone.
Topics: Ascorbic Acid; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Free Radical Scavengers; Hydrogen Peroxide; Hydrogenation; Hydromorphone; Hydroxides; Hydroxyl Radical; Morphine; Oxidation-Reduction; Superoxides | 1992 |
Affinity labeling of mu opioid receptors by sulfhydryl alkylating derivatives of morphine and morphinone.
Topics: Affinity Labels; Alkylating Agents; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Dithiothreitol; Hydromorphone; In Vitro Techniques; Kinetics; Morphine Derivatives; Rats; Receptors, Opioid; Receptors, Opioid, mu; Sulfhydryl Reagents; Temperature | 1990 |
A new metabolic pathway of morphine: in vivo and in vitro formation of morphinone and morphine-glutathione adduct in guinea pig.
Topics: Animals; Bile; Glutathione; Guinea Pigs; Hydromorphone; In Vitro Techniques; Lithocholic Acid; Liver; Male; Morphine; Naloxone | 1990 |
Microbial degradation of the morphine alkaloids: identification of morphine as an intermediate in the metabolism of morphine by Pseudomonas putida M10.
Topics: Biodegradation, Environmental; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Hydromorphone; Magnetic Resonance Spectroscopy; Molecular Structure; Morphine; NADPH Dehydrogenase; Oxidation-Reduction; Pseudomonas; Thebaine | 1990 |
Morphine metabolism in isolated rat hepatocytes and its implications for hepatotoxicity.
Topics: Animals; Cell Survival; Glutathione; Hydromorphone; Isoenzymes; L-Lactate Dehydrogenase; Liver; Male; Morphine; Morphine Derivatives; Naloxone; Perfusion; Rats; Rats, Inbred Strains | 1986 |
Method for determination of morphinone in urine and bile of guinea pig by high-performance liquid chromatography.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Dihydromorphine; Guinea Pigs; Hydromorphone; Mercaptoethanol; Morphine; Morphine Derivatives | 1987 |
Purification and characterization of guinea pig liver morphine 6-dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Guinea Pigs; Hydromorphone; Kinetics; Liver; Magnetic Resonance Spectroscopy; Mercaptoethanol; Morphine; NAD; NADP | 1985 |
Effect of morphinone on opiate receptor binding and morphine-elicited analgesia.
Topics: Analgesia; Animals; Cysteine; Dihydromorphine; Glutathione; Hydromorphone; Kinetics; Mice; Morphine; Naloxone; Receptors, Opioid | 1982 |
Activities of morphinone and N-(cyclopropylmethyl)normorphinone at opioid receptors.
Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Hydromorphone; Ileum; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens | 1984 |
14 beta-[(p-nitrocinnamoyl)amino]morphinones, 14 beta-[(p-nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: synthesis and receptor activity.
Topics: Animals; Brain; Cattle; Cinnamates; Codeine; Hydromorphone; Receptors, Opioid; Structure-Activity Relationship | 1993 |
Purification, characterization and partial primary structure of morphine 6-dehydrogenase from rabbit liver cytosol.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Chromatography, Agarose; Chromatography, High Pressure Liquid; Cytosol; Enzyme Inhibitors; Hydromorphone; Kinetics; Liver; Male; Molecular Sequence Data; Morphine; NADP; Peptide Fragments; Rabbits; Sequence Analysis; Serine Endopeptidases; Steroids; Substrate Specificity | 1997 |
In vivo and in vitro formation of morphinone from morphine in rat.
Topics: Alcohol Oxidoreductases; Animals; Bile; Cattle; Cricetinae; Female; Glutathione; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Subcutaneous; Male; Mice; Microsomes, Liver; Morphine; Narcotics; Rabbits; Rats; Rats, Wistar; Species Specificity | 1997 |
Mechanistic studies of morphine dehydrogenase and stabilization against covalent inactivation.
Topics: Alcohol Oxidoreductases; Catalytic Domain; Enzyme Activation; Enzyme Stability; Hydromorphone; Isomerism; Kinetics; Substrate Specificity | 2000 |
The analgesic equivalence to morphine and relative side action liability of oxymorphone (14-hydroxydihydro morphinone).
Topics: Analgesics; Humans; Hydromorphone; Morphine; Oxymorphone | 1959 |
Bioactivation of morphine in human liver: isolation and identification of morphinone, a toxic metabolite.
Topics: Alcohol Oxidoreductases; Biotransformation; Humans; Hydromorphone; Magnetic Resonance Spectroscopy; Microsomes, Liver; Morphine | 2005 |
Decoration of the aromatic ring of dihydrocodeinone (hydrocodone) and 14-hydroxydihydrocodeinone (oxycodone).
Topics: Acids; Bromine; Hydrocodone; Hydromorphone; Iodine; Molecular Structure; Narcotics; Oxycodone | 2005 |
Glutathione and Glutathione-Like Sequences of Opioid and Aminergic Receptors Bind Ascorbic Acid, Adrenergic and Opioid Drugs Mediating Antioxidant Function: Relevance for Anesthesia and Abuse.
Topics: Analgesics, Opioid; Ascorbic Acid; Dehydroascorbic Acid; Enkephalin, Methionine; Glutathione; Humans; Hydromorphone; Methadone; Morphine; Naloxone; Peptides; Receptors, Adrenergic, beta-2; Receptors, Dopamine D1; Receptors, Histamine H1; Receptors, Opioid; Receptors, Opioid, mu | 2020 |
Biotransformation of Morphinone and Its Glutathione Adduct Derived from Morphine by Anaerobic Gut Microbes in Guinea Pigs.
Topics: Anaerobiosis; Animals; Biotransformation; Gastrointestinal Microbiome; Glutathione; Guinea Pigs; Hydromorphone; Morphine | 2022 |