hydromorphone and morphinans

hydromorphone has been researched along with morphinans in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199021 (87.50)18.7374
1990's0 (0.00)18.2507
2000's3 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abood, LG; Atkinson, GH; MacNeil, M1
Cohen, H; Henderson, SK1
Fanelli, RJ; Jasinski, DR; London, ED; Szikszay, M1
Fanelli, R; Jasinski, D; London, E; Szikszay, M1
Bigelow, GE; Liebson, IA; Preston, KL3
May, EL; Sargent, LJ1
Ferko, AP; Gero, A1
Gorodetzky, CW1
Eddy, NB; May, EL1
Klee, WA; Streaty, RA1
Terenius, L1
Herz, A; Teschemacher, HJ; von Cube, B1
Röthig, J1
Herz, A; Hess, R; Teschemacher, H; von Cube, B1
Bree, MP; Mello, NK; Mendelson, JH2
Dashwood, MR; Kiang, JG; Wei, ET1
France, CP; Jacobson, AE; Woods, JH2
Consonni, A; Giardini, A; Lesma, G; Passarella, D; Silvani, A1
Husbands, SM; Lewis, JW1
Ananthan, S; Bartlett, JL; Bilsky, EJ; Davis, P; Dersch, CM; Khare, NK; Porreca, F; Rothman, RB; Saini, SK; Seitz, LE1

Reviews

2 review(s) available for hydromorphone and morphinans

ArticleYear
[Analgesics. 32].
    Pharmazeutische Praxis, 1969, Volume: 5

    Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine

1969
Opioid ligands having delayed long-term antagonist activity: potential pharmacotherapies for opioid abuse.
    Mini reviews in medicinal chemistry, 2003, Volume: 3, Issue:2

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Drug Evaluation, Preclinical; Etorphine; Humans; Hydromorphone; Ligands; Morphinans; Narcotic Antagonists; Receptors, Opioid, mu; Structure-Activity Relationship; Substance-Related Disorders

2003

Trials

2 trial(s) available for hydromorphone and morphinans

ArticleYear
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2

    Topics: Adult; Butorphanol; Cognition; Double-Blind Method; Humans; Hydromorphone; Injections, Intramuscular; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Psychomotor Performance; Substance Withdrawal Syndrome

1988
Antagonist effects of nalbuphine in opioid-dependent human volunteers.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Methadone; Morphinans; Nalbuphine; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome

1989

Other Studies

20 other study(ies) available for hydromorphone and morphinans

ArticleYear
Stereospecific opiate binding in human erythrocyte membranes and changes in heroin addicts.
    Journal of neuroscience research, 1976, Volume: 2, Issue:5-6

    Topics: Adult; Brain; Calcium Chloride; Dextrorphan; Erythrocyte Membrane; Erythrocytes; Female; Heroin Dependence; Humans; Hydromorphone; Kinetics; Levorphanol; Male; Morphinans; Phospholipases; Receptors, Opioid; Serine; Sodium Chloride; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes; Trypsin

1976
Nalbuphine augmentation of analgesia and reversal of side effects following epidural hydromorphone.
    Anesthesiology, 1986, Volume: 65, Issue:2

    Topics: Adult; Analgesia; Anesthesia, Epidural; Cesarean Section; Female; Humans; Hydromorphone; Morphinans; Nalbuphine; Pruritus

1986
Differential effects of mu and kappa opioid analgesics on cerebral glucose utilization in the rat.
    Brain research, 1987, Oct-06, Volume: 422, Issue:2

    Topics: Animals; Autoradiography; Blood Pressure; Brain; Carbon Dioxide; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; Heart Rate; Hydromorphone; Male; Morphinans; Morphine; Nalbuphine; Organ Specificity; Oxygen; Oxymorphone; Rats; Rats, Inbred F344; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1987
Effects of opioid analgesics on local cerebral glucose utilization.
    NIDA research monograph, 1986, Volume: 75

    Topics: Animals; Brain; Deoxy Sugars; Deoxyglucose; Hydromorphone; Male; Morphinans; Morphine; Nalbuphine; Organ Specificity; Oxymorphone; Rats; Rats, Inbred F344

1986
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
    NIDA research monograph, 1987, Volume: 76

    Topics: Butorphanol; Heart Rate; Humans; Hydromorphone; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Pupil; Respiration; Skin Temperature; Substance Withdrawal Syndrome; Surveys and Questionnaires

1987
Agonists--antagonists derived from desomorphine and metopon.
    Journal of medicinal chemistry, 1970, Volume: 13, Issue:6

    Topics: Animals; Haplorhini; Humans; Hydromorphone; Mice; Morphinans; Morphine; Nalorphine; Substance-Related Disorders

1970
Interactions of narcotics and their antagonists with human serum esterase. 3. Structure-activity studies.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 187, Issue:2

    Topics: Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Esterases; Humans; Hydrogen-Ion Concentration; Hydromorphone; Isoquinolines; Ketones; Kinetics; Morphinans; Morphine; Piperidines; Procaine; Receptors, Drug; Spectrophotometry; Stereoisomerism

1970
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
The search for a better analgesic.
    Science (New York, N.Y.), 1973, Aug-03, Volume: 181, Issue:4098

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorphanol; Meperidine; Methadone; Morphinans; Morphine Dependence; Structure-Activity Relationship

1973
Narcotic receptor sites in morphine-dependent rats.
    Nature, 1974, Mar-01, Volume: 248, Issue:5443

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Drug Tolerance; Female; Humans; Hydromorphone; In Vitro Techniques; Male; Morphinans; Morphine; Morphine Dependence; Naloxone; Physostigmine; Rats; Receptors, Drug; Tritium

1974
Contribution of 'receptor' affinity to analgesic potency.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: 1-Propanol; Analgesics; Animals; Binding, Competitive; Brain; Cyclopropanes; Fentanyl; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Intravenous; Levorphanol; Meperidine; Methadone; Morphinans; Morphine; Pentanols; Receptors, Drug

1974
[A comparison of the analgetic action of intravenously and intraventricularly injected morphine-like substances, taking into account their fat solubility].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:1

    Topics: Animals; Codeine; Hydromorphone; Lipids; Morphinans; Morphine; Rabbits; Solubility

1969
[Permeation of active morphine-like substances at their sites of antinociceptive action in the brain as a function of their lipid-solubility following intravenous and intraventricular application].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:5

    Topics: Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Dental Pulp Test; Fentanyl; Hydromorphone; Ketones; Kinetics; Levorphanol; Lipids; Methadone; Morphinans; Morphine; Piperidines; Rabbits; Solubility; Tritium

1970
Comparison of the effects of buprenorphine and methadone on opiate self-administration in primates.
    NIDA research monograph, 1982, Volume: 41

    Topics: Animals; Buprenorphine; Dose-Response Relationship, Drug; Eating; Heroin Dependence; Humans; Hydromorphone; Macaca mulatta; Macaca nemestrina; Male; Methadone; Morphinans; Opioid-Related Disorders; Self Administration

1982
Comparison of buprenorphine and methadone effects on opiate self-administration in primates.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2

    Topics: Animals; Buprenorphine; Depression, Chemical; Disease Models, Animal; Feeding Behavior; Heroin; Humans; Hydromorphone; Macaca mulatta; Macaca nemestrina; Methadone; Morphinans; Opioid-Related Disorders; Self Administration

1983
An etorphine-evoked vagal reflex in rats is inhibited by naloxone, N-methylnaloxone, and SMS 201-995.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 266, Issue:1

    Topics: Animals; Blood Pressure; Etorphine; Heart Rate; Hydromorphone; Male; Morphinans; Naloxone; Octreotide; Oxymorphone; Rats; Rats, Inbred Strains; Reflex; Respiration; Somatostatin; Vagus Nerve

1983
Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3

    Topics: Animals; Buprenorphine; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Hydromorphone; Morphinans; Morphine; Naltrexone; Oxymorphone; Time Factors

1984
Irreversible and reversible narcotic agonists: discriminative and analgesic effects of buprenorphine, oxymorphazone, and morphine.
    NIDA research monograph, 1984, Volume: 49

    Topics: Animals; Buprenorphine; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Hydromorphone; Mice; Morphinans; Morphine; Naltrexone; Nociceptors; Oxymorphone

1984
A convenient synthesis of delta(7,8)-morphinan-6-one and its direct oxidation to 14-hydroxy-delta(7,8)-morphinan-6-one.
    Bioorganic & medicinal chemistry letters, 2002, Aug-05, Volume: 12, Issue:15

    Topics: Cyclization; Hydrogenation; Hydromorphone; Hydroxides; Ketones; Manganese Compounds; Morphinans; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxides; Silicon Dioxide; Stereoisomerism

2002
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Analgesics; Animals; Binding Sites; Brain; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Oxymorphone; Pyridines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens

2004