hydromorphone and methadone

hydromorphone has been researched along with methadone in 116 studies

Research

Studies (116)

TimeframeStudies, this research(%)All Research%
pre-199049 (42.24)18.7374
1990's17 (14.66)18.2507
2000's17 (14.66)29.6817
2010's23 (19.83)24.3611
2020's10 (8.62)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, BE; Prada, JA1
Geber, WF; Hung, CY; Lefkowitz, SS1
Resnick, RB; Volavka, J1
Rubenstein, RB; Spira, I; Wolff, WI1
Horng, JS; Smits, SE; Wong, DT1
Baskerville, JC; Brands, B; Gowdey, CW; Hirst, M2
Grabowski, J; Jordan-Hayes, J; O'Brien, CP; Ternes, JW; Wellerstein, H1
Bigelow, GE; Liebson, IA; Preston, KL; Strain, EC2
Bigelow, GE; Liebson, IA; Preston, KL5
Bigelow, GE; Liebson, I; Preston, KL; Strain, EC1
Ennis, M; Lorenz, W; Nehring, E; Schneider, C1
Breimer, DD; de Boer, AG; van Hoogdalem, E1
Foley, KM; Inturrisi, CE; Moulin, DE; Portenoy, RK; Rogers, A1
Coleman, RR; Lo, SL1
Bickel, W; Bigelow, GE; Liebson, IA; Preston, KL1
Bickel, WK; Bigelow, GE; Jasinski, DR; Johnson, RE; Liebson, IA; Stitzer, ML1
Foley, KM; Houde, RW; Inturrisi, CE; Moulin, DE; Nip, TJ; Reidenberg, B; Wallenstein, S; Weinberg, DS1
Gorodetzky, CW1
Eddy, NB; May, EL1
Baden, MM; Huang, JC1
Terenius, L2
Bastos, ML; Jukofsky, D; Mulé, SJ1
Kreuzer, H; Spiller, P1
Dole, VP; Kreek, MJ; Nyswander, ME2
Elliott, HW; Hine, CH; Nomof, N; Parker, KD1
Ettinger, MJ; Gero, A2
Juvara, I; Radulesco, D1
Röthig, J1
Fujimoto, JM; Wang, RI1
Herz, A; Hess, R; Teschemacher, H; von Cube, B1
Gero, A1
Bigelow, GE; Liebson, IA; Preston, KL; Stitzer, ML1
Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE1
Miller, RR1
Bree, MP; Mello, NK; Mendelson, JH2
Bigelow, GE; Liebson, IA; McCaul, ME; Stitzer, ML1
Bruera, E; Thomas, Z1
Bigelow, GE; Preston, KL; Stitzer, ML; Walsh, SL1
Bruera, E; Fainsinger, RL; Inturrisi, C; Spachynski, K; Suarez-Almazor, M; Watanabe, S1
Belzile, M; Bruera, E; Hanson, J; Kuehn, N; Pereira, J; Watanabe, S1
Bruera, E; Fan, D; Vigano', A1
Borsook, D; Chandler, SW; Manfredi, PL; Payne, R1
Belzile, M; Bruera, E; De Conno, F; Groff, L; Hanson, J; Pereira, J; Ripamonti, C1
Hameedi, FA; Kosten, TA; Kosten, TR; Oliveto, AH; Rosen, MI; Woods, SW1
Belgrade, M; River, Y1
Angst, MS; Brose, WG; Dyck, JB1
Mercadante, S1
Charuvastra, VC; Compton, P; Kintaudi, K; Ling, W1
Arcuri, E; Centulio, F; Ciocca, F; D'Angiolino, G; Ginobbi, P; Marcelli, ME; Pelagalli, L; Tirelli, W1
Casas, JR; Cherny, N; Conno, F; Hanks, GW; Hanna, M; Kalso, E; McQuay, HJ; Mercadante, S; Meynadier, J; Poulain, P; Radbruch, L; Ripamonti, C; Sawe, J; Twycross, RG; Ventafridda, V1
Derby, S; Fischberg, D; Kornick, C; Manfredi, PL; Moryl, N; Payne, R; Santiago-Palma, J1
Eap, CB; Melichar, JK; Myles, JS; Nutt, DJ1
MAY, EL1
PARIS, J; U BOIS, R; VANDENDORP, F1
MEYERSTEIN, AN1
WANG, RI1
HAMBURGER, E1
LASAGNA, L1
SHEMANO, I; WENDEL, H1
COLLINS, RJ; WEEKS, JR1
Carson, S; Chung, KS; Glassman, D; Vadivelu, N1
Booth, CM; Cottrell, W; Seccareccia, D; Zimmermann, C1
Golianu, B; Lin, YC1
Berdine, HJ; Nesbit, SA1
Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F1
Friedrichsdorf, SJ; Kang, TI1
Greenwald, MK1
POWERS, BR1
Bond, BS1
Bailey, JE; Campagna, E; Dart, RC1
Anderson, BJ; Craig, F; Michel, E; Zernikow, B1
Anis, A; Brissette, S; Guh, D; Lauzon, P; Marsh, DC; Oviedo-Joekes, E; Schechter, MT1
Anis, A; Brissette, S; Guh, D; Krausz, M; Marsh, DC; Nosyk, B; Oviedo-Joekes, E; Schechter, MT1
Ewan, EE; Martin, TJ1
Barrett, SP; Fulton, HG; Macisaac, C; Stewart, SH1
Brody, J; Hardin, C; LeBaron, V; Lee, EM; Snyder, L1
Brecht, K; Giladi, H; Hebert, TE; Joseph, L; Perlman, R; Shir, Y; Ware, MA1
Ilkiw, JE; Pypendop, BH; Shilo-Benjamini, Y2
Bruera, E; Didwaniya, N; Gottumukkala, RS; Reddy, A1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
Anis, AH; Brissette, S; Chettiar, J; Lock, K; Marchand, K; Marsh, DC; Oviedo-Joekes, E; Schechter, MT1
Flory, JH; Koranteng, L; Moryl, N; Thaler, HT; Wiesenthal, AC1
Cederholm, SK; Durieux, ME; Fernández, L; Kazemi, A; McMurry, TL; Naik, BI; Nemergut, EC1
Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE1
Bell, RF; Derry, S; Moore, RA; Wee, B; Wiffen, PJ1
Haymond, S; Heiman, H; Nagpal, G1
Aruga, E; Takagi, Y1
Anis, AH; Bansback, N; Brissette, S; Guh, D; Harrison, S; Janmohamed, A; Krausz, M; MacDonald, S; Marsh, DC; Oviedo-Joekes, E; Schechter, MT1
Blood, J; Brunt, LM; Deych, E; Kharasch, ED; Komen, H1
Linas, BP1
Blackney, KA; Edwards, DA; Kamdar, NV; Liu, CA1
Amirnovin, R; Koh, JY; Lieu, P; Nelson, LP; Okuhara, C; Rodgers, JW; Sanchez-Pinto, LN1
Ammar, D; Baron, L; Chvetzoff, G; Collin, E; Delorme, C; Delorme, T; Faure, S; Filbet, M; Hubault, P; Jovenin, N; Krakowski, I; Magnet, M; Michenot, N; Minello, C; Poulain, P; Rostaing, S1
Churchill, B; Root-Bernstein, R; Turke, M1
Agin-Liebes, G; Bigelow, GE; Edwards, RR; Gruber, VA; Huhn, AS; Smith, MT; Strain, EC; Tompkins, DA1
Beck, O; Böttcher, M; Keller, T; Lierheimer, S; Monticelli, FC1
Matsuda, Y; Niki, K; Okamoto, Y; Omae, T; Takagi, T; Takemura, M; Ueda, M1
Eidbo, SA; Hagedorn, JD; Kaufman, DE; Kropp Lopez, AK; Mathew, V; McCall, KL; Nichols, SD; Piper, BJ1
Coulter, C; Garnier, M; Moore, C1
Casias, T; Hernandez, B; Hylton, J; Krause, BM; Mok, V; Noonan, KJ; Sweetman, S; Walker, BJ1
Bateman, BT; Esposito, DB; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Straub, L; Werler, MM1
Caputo, A; Christopher, C; Compton, P; Delgado, MK; Lowenstein, M; McFadden, R; Olenik, JM; Perrone, J; Ronning, K; Sigueza, AL; Thakrar, AP; Uritsky, TJ; Winston, A1
Dräger, DL1

Reviews

12 review(s) available for hydromorphone and methadone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
    Clinical pharmacokinetics, 1991, Volume: 21, Issue:1

    Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid

1991
[Analgesics. 32].
    Pharmazeutische Praxis, 1969, Volume: 5

    Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine

1969
Opioid rotation for cancer pain: rationale and clinical aspects.
    Cancer, 1999, Nov-01, Volume: 86, Issue:9

    Topics: Analgesics, Opioid; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Narcotics; Neoplasms; Pain

1999
DRUG ADDICTION: A REVIEW.
    The Journal of school health, 1964, Volume: 34

    Topics: Adolescent; Amphetamine; Amphetamines; Barbiturates; Cannabis; Codeine; Heroin; Humans; Hydromorphone; Jurisprudence; Meperidine; Mescaline; Methadone; Morphine Dependence; Nalorphine; Narcotic Antagonists; Psychotherapy; Statistics as Topic; Substance-Related Disorders

1964
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS.
    Pharmacological reviews, 1964, Volume: 16

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology

1964
The management of pain in children with life-limiting illnesses.
    Pediatric clinics of North America, 2007, Volume: 54, Issue:5

    Topics: Analgesics, Opioid; Child; Chronic Disease; Codeine; Fentanyl; Humans; Hydromorphone; Ketamine; Methadone; Morphine; Nociceptors; Oxycodone; Pain; Pain Measurement; Severity of Illness Index

2007
Equianalgesia: applying evidence-based practice guidelines.
    Clinical journal of oncology nursing, 2008, Volume: 12, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Codeine; Drug Monitoring; Evidence-Based Medicine; Humans; Hydromorphone; Methadone; Morphine; Neoplasms; Nurse's Role; Nursing Assessment; Oncology Nursing; Pain; Practice Guidelines as Topic; Therapeutic Equivalency; Treatment Outcome

2008
Pediatric palliative care: use of opioids for the management of pain.
    Paediatric drugs, 2009, Volume: 11, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Child; Delayed-Action Preparations; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Narcotics; Pain; Palliative Care

2009
Opioids for cancer pain - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2017, 07-06, Volume: 7

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Fentanyl; Humans; Hydromorphone; Methadone; Oxycodone; Phenols; Review Literature as Topic; Tapentadol; Tramadol

2017
[New Opioid Options in Japan - Methadone, Tapentadol and Hydromorphone].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:2

    Topics: Analgesics, Opioid; Humans; Hydromorphone; Methadone; Pain Management; Phenols; Receptors, Opioid; Tapentadol

2018
[Opioid switch and change of route of administration in cancer patients treated by morphine].
    Bulletin du cancer, 2018, Volume: 105, Issue:11

    Topics: Administration, Oral; Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Drug Substitution; Fentanyl; France; Humans; Hydromorphone; Injections, Intravenous; Injections, Subcutaneous; Methadone; Morphine; Oxycodone; Phenols; Tapentadol

2018

Trials

19 trial(s) available for hydromorphone and methadone

ArticleYear
Drug-seeking behavior during methadone maintenance.
    Psychopharmacologia, 1975, Volume: 41, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydromorphone; Injections, Intravenous; Male; Methadone; Motivation; Physical Exertion; Reward; Substance-Related Disorders; Time Factors

1975
Acute effects of buprenorphine, hydromorphone and naloxone in methadone-maintained volunteers.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Adult; Buprenorphine; Cognition; Drug Interactions; Hemodynamics; Humans; Hydromorphone; Injections, Intramuscular; Male; Methadone; Naloxone; Psychomotor Performance; Substance Abuse Treatment Centers; Substance-Related Disorders

1992
A clinical trial of buprenorphine: I. Comparison with methadone in the detoxification of heroin addicts. II. Examination of its opioid blocking properties.
    NIDA research monograph, 1987, Volume: 76

    Topics: Adult; Analysis of Variance; Buprenorphine; Clinical Trials as Topic; Heroin Dependence; Humans; Hydromorphone; Male; Methadone; Narcotic Antagonists; Substance Withdrawal Syndrome

1987
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2

    Topics: Adult; Butorphanol; Cognition; Double-Blind Method; Humans; Hydromorphone; Injections, Intramuscular; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Psychomotor Performance; Substance Withdrawal Syndrome

1988
Antagonist effects of nalbuphine in opioid-dependent human volunteers.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Methadone; Morphinans; Nalbuphine; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome

1989
Precipitated withdrawal by pentazocine in methadone-maintained volunteers.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Adult; Behavior; Humans; Hydromorphone; Male; Methadone; Naloxone; Pentazocine; Psychomotor Performance; Substance Withdrawal Syndrome; Time Factors

1993
Acute administration of buprenorphine in humans: partial agonist and blockade effects.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1

    Topics: Adult; Buprenorphine; Cross-Over Studies; Double-Blind Method; Humans; Hydromorphone; Male; Methadone; Narcotic Antagonists; Receptors, Opioid; Respiration

1995
Custom-made capsules and suppositories of methadone for patients on high-dose opioids for cancer pain.
    Pain, 1995, Volume: 62, Issue:2

    Topics: Aged; Analgesics, Opioid; Capsules; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Male; Methadone; Middle Aged; Neoplasms; Pain; Prospective Studies; Suppositories

1995
Pain responses in methadone-maintained opioid abusers.
    Journal of pain and symptom management, 2000, Volume: 20, Issue:4

    Topics: Adult; Cold Temperature; Drug Interactions; Female; Humans; Hydromorphone; Ketorolac; Male; Methadone; Middle Aged; Opioid-Related Disorders; Pain; Pain Measurement; Pain Threshold; Pressure; Reaction Time

2000
Pitfalls of opioid rotation: substituting another opioid for methadone in patients with cancer pain.
    Pain, 2002, Volume: 96, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Humans; Hydromorphone; Levorphanol; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Patient Satisfaction; Prospective Studies

2002
Diacetylmorphine versus methadone for the treatment of opioid addiction.
    The New England journal of medicine, 2009, Aug-20, Volume: 361, Issue:8

    Topics: Administration, Oral; Adult; Cocaine-Related Disorders; Double-Blind Method; Drug Overdose; Female; Heroin; Heroin Dependence; Humans; Hydromorphone; Illicit Drugs; Injections; Male; Methadone; Substance Abuse Detection; Substance Abuse, Intravenous

2009
Double-blind injectable hydromorphone versus diacetylmorphine for the treatment of opioid dependence: a pilot study.
    Journal of substance abuse treatment, 2010, Volume: 38, Issue:4

    Topics: Adult; Double-Blind Method; Follow-Up Studies; Heroin; Heroin Dependence; Humans; Hydromorphone; Injections; Methadone; Narcotics; Opioid-Related Disorders; Pilot Projects; Severity of Illness Index; Time Factors

2010
Intradialytic clearance of opioids: methadone versus hydromorphone.
    Pain, 2013, Volume: 154, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Follow-Up Studies; Humans; Hydromorphone; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Methadone; Middle Aged; Prospective Studies; Renal Dialysis

2013
Bioavailability of morphine, methadone, hydromorphone, and oxymorphone following buccal administration in cats.
    Journal of veterinary pharmacology and therapeutics, 2014, Volume: 37, Issue:3

    Topics: Administration, Buccal; Analgesics, Opioid; Animals; Biological Availability; Cats; Female; Hydromorphone; Methadone; Morphine; Oxymorphone

2014
A chance to stop and breathe: participants' experiences in the North American Opiate Medication Initiative clinical trial.
    Addiction science & clinical practice, 2014, Sep-29, Volume: 9

    Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Heroin; Humans; Hydromorphone; Injections, Subcutaneous; Male; Methadone; North America; Opioid-Related Disorders; Outcome Assessment, Health Care; Research Design; Young Adult

2014
The Effect of Dexmedetomidine on Postoperative Opioid Consumption and Pain After Major Spine Surgery.
    Anesthesia and analgesia, 2016, Volume: 122, Issue:5

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Back Pain; Chi-Square Distribution; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Early Termination of Clinical Trials; Female; Fentanyl; Humans; Hydromorphone; Lumbar Vertebrae; Male; Methadone; Middle Aged; Odds Ratio; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Prospective Studies; Thoracic Vertebrae; Time Factors; Treatment Outcome; Virginia

2016
Effect of morphine, methadone, hydromorphone or oxymorphone on the thermal threshold, following intravenous or buccal administration to cats.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:6

    Topics: Administration, Buccal; Administration, Intravenous; Analgesics, Opioid; Animals; Cats; Cross-Over Studies; Female; Hydromorphone; Methadone; Morphine; Oxymorphone; Pain Threshold

2016
Intraoperative Methadone in Same-Day Ambulatory Surgery: A Randomized, Double-Blinded, Dose-Finding Pilot Study.
    Anesthesia and analgesia, 2019, Volume: 128, Issue:4

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Double-Blind Method; Drug Administration Schedule; Female; Fentanyl; Humans; Hydromorphone; Intraoperative Period; Male; Methadone; Middle Aged; Pain Management; Pain Measurement; Pain, Postoperative; Pilot Projects; Postoperative Period; Treatment Outcome

2019
Methadone maintenance patients lack analgesic response to a cumulative intravenous dose of 32 mg of hydromorphone.
    Drug and alcohol dependence, 2021, 09-01, Volume: 226

    Topics: Analgesics, Opioid; Drug Tolerance; Humans; Hydromorphone; Methadone; Opioid-Related Disorders

2021

Other Studies

85 other study(ies) available for hydromorphone and methadone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Effect of morphine, hydromorphone, methadone, mescaline, trypan blue, vitamin A, sodium salicylate, and caffeine on the serum interferon level in response to viral infection.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:2

    Topics: Animals; Caffeine; Hydromorphone; Interferons; Male; Mescaline; Methadone; Mice; Morphine; Salicylates; Trypan Blue; Vesicular stomatitis Indiana virus; Virus Diseases; Vitamin A

1975
Letter: Treatment of accidental naltrexone-induced withdrawal.
    The American journal of psychiatry, 1976, Volume: 133, Issue:2

    Topics: Adult; Humans; Hydromorphone; Male; Methadone; Naloxone; Naltrexone; Substance Withdrawal Syndrome

1976
Management of surgical problems in patients on methadone maintenance.
    American journal of surgery, 1976, Volume: 131, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cocaine; Female; Heroin Dependence; Humans; Hydromorphone; Liver Diseases; Lung Diseases; Male; Methadone; Middle Aged; Morphine Dependence; Postoperative Complications; Substance Withdrawal Syndrome; Substance-Related Disorders; Surgical Procedures, Operative; Surgical Wound Infection; Thrombophlebitis

1976
The binding of the optical isomers of methadone, alpha-methadol, alpha-acetylmethadol and their N-demethylated derivatives to the opiate receptors of rat brain.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 14, Issue:4

    Topics: Animals; Brain; Dealkylation; Hydromorphone; In Vitro Techniques; Isomerism; Methadone; Methadyl Acetate; Naloxone; Rats; Receptors, Drug

1976
Dependence in rats after one injection of heroin-, LAAM- or hydromorphone-zinc tannate.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Heroin; Heroin Dependence; Humans; Hydromorphone; Methadone; Methadyl Acetate; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1979
Conditioned drug responses to naturalistic stimuli.
    NIDA research monograph, 1979, Volume: 27

    Topics: Conditioning, Psychological; Heart Rate; Humans; Hydromorphone; Methadone; Naltrexone; Opioid-Related Disorders; Personality Tests; Self Administration; Skin Temperature

1979
Discrimination of butorphanol and nalbuphine in opioid-dependent humans.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3

    Topics: Adult; Behavior; Blood Pressure; Body Temperature; Butorphanol; Discrimination, Psychological; Generalization, Psychological; Humans; Hydromorphone; Male; Methadone; Middle Aged; Nalbuphine; Naloxone; Psychomotor Performance; Pupil; Receptors, Opioid

1990
The effects of buprenorphine in methadone-dependent volunteers.
    NIDA research monograph, 1990, Volume: 105

    Topics: Buprenorphine; Double-Blind Method; Humans; Hydromorphone; Male; Methadone; Naloxone; Opioid-Related Disorders; Pupil

1990
Histamine release induced by opioid analgesics: a comparative study using porcine mast cells.
    Agents and actions, 1991, Volume: 33, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Histamine Release; Hydromorphone; Kidney; Liver; Lung; Mast Cells; Meperidine; Methadone; Morphine; Myocardium; Oxycodone; Swine

1991
Self-administration of clonidine, oxazepam, and hydromorphone by patients undergoing methadone detoxification.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:2

    Topics: Adult; Clonidine; Drug Administration Schedule; Humans; Hydromorphone; Male; Methadone; Opioid-Related Disorders; Oxazepam; Psychomotor Performance; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders; Surveys and Questionnaires

1985
I.v. infusion of opioids for cancer pain: clinical review and guidelines for use.
    Cancer treatment reports, 1986, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Administration Schedule; Drug Evaluation; Humans; Hydromorphone; Infant; Infusions, Parenteral; Levorphanol; Methadone; Middle Aged; Morphine; Narcotics; Neoplasms; Oxymorphone; Pain, Intractable; Palliative Care; Retrospective Studies

1986
Exceptionally high narcotic analgesic requirements in a terminally ill cancer patient.
    Clinical pharmacy, 1986, Volume: 5, Issue:10

    Topics: Adult; Analgesics, Opioid; Combined Modality Therapy; Drug Tolerance; Female; Humans; Hydromorphone; Methadone; Morphine; Neoplasms; Pain

1986
Three-choice drug discrimination in opioid-dependent humans: hydromorphone, naloxone and saline.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3

    Topics: Adult; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Psychological; Humans; Hydromorphone; Male; Methadone; Naloxone; Opioid-Related Disorders; Psychomotor Performance

1987
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
    NIDA research monograph, 1987, Volume: 76

    Topics: Butorphanol; Heart Rate; Humans; Hydromorphone; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Pupil; Respiration; Skin Temperature; Substance Withdrawal Syndrome; Surveys and Questionnaires

1987
Sublingual absorption of selected opioid analgesics.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Analysis of Variance; Biological Availability; Buprenorphine; Fentanyl; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Mouth; Naloxone; Oxycodone; Time Factors

1988
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
The search for a better analgesic.
    Science (New York, N.Y.), 1973, Aug-03, Volume: 181, Issue:4098

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorphanol; Meperidine; Methadone; Morphinans; Morphine Dependence; Structure-Activity Relationship

1973
Rapid methods of screening micro-quantities of abused drugs from urine samples for microcrystal tests.
    Clinical toxicology, 1973, Volume: 6, Issue:3

    Topics: Acids; Alkalies; Alkaloids; Chromatography, Thin Layer; Codeine; Crystallization; Crystallography; Heroin Dependence; Humans; Hydromorphone; Indicators and Reagents; Meperidine; Methadone; Methods; Morphine; Nicotine; Quinine; Substance-Related Disorders

1973
Stereospecific uptake of narcotic analgesics by a subcellular fraction of the guinea-pig ileum. A preliminary communication.
    Upsala journal of medical sciences, 1973, Volume: 78, Issue:3

    Topics: Analgesics; Animals; Codeine; Dextromoramide; Female; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Intestinal Absorption; Levorphanol; Male; Methadone; Morphine; Muscle, Smooth; Nalorphine; Naloxone; Narcotics; Subcellular Fractions; Tritium

1973
Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Apomorphine; Barbiturates; Chromatography, Thin Layer; Cocaine; Codeine; Cross Reactions; Cyclazocine; Dextromethorphan; Dextropropoxyphene; Evaluation Studies as Topic; Hemagglutination Inhibition Tests; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Radioimmunoassay; Spectrometry, Fluorescence; Substance-Related Disorders; Time Factors; Tritium

1974
Contribution of 'receptor' affinity to analgesic potency.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: 1-Propanol; Analgesics; Animals; Binding, Competitive; Brain; Cyclopropanes; Fentanyl; Guinea Pigs; Hydromorphone; In Vitro Techniques; Injections, Intravenous; Levorphanol; Meperidine; Methadone; Morphinans; Morphine; Pentanols; Receptors, Drug

1974
[Analgesia in myocardial infarct].
    Zeitschrift fur Kardiologie, 1974, Volume: 63, Issue:12

    Topics: Analgesics; Diazepam; Heart; Hemodynamics; Heroin; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Myocardial Infarction; Nitrogen Oxides; Pain; Pentazocine; Respiration

1974
Narcotic blockade.
    Archives of internal medicine, 1966, Volume: 118, Issue:4

    Topics: Drug Tolerance; Follow-Up Studies; Heroin; Humans; Hydromorphone; Injections, Intravenous; Methadone; Morphine; Rehabilitation; Substance Withdrawal Syndrome; Substance-Related Disorders

1966
Narcotic blockade--a medical technique for stopping heroin use by addicts.
    Transactions of the Association of American Physicians, 1966, Volume: 79

    Topics: Euphoria; Heroin; Humans; Hydromorphone; Methadone; Morphine; Substance Withdrawal Syndrome; Substance-Related Disorders

1966
Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test.
    Journal of forensic sciences, 1966, Volume: 11, Issue:2

    Topics: Amphetamine; California; Cocaine; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Nalorphine; Pupil; Substance-Related Disorders

1966
Interactions of narcotics and their antagonists with human serum esterase. II: nature of the antagonism.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Drug Antagonism; Enzymes; Esterases; Humans; Hydromorphone; Levorphanol; Methadone; Models, Theoretical; Morphine; Nalorphine; Narcotic Antagonists; Procaine; Spectrophotometry

1966
Interactions of narcotics and their antagonists with human serum esterase. I: sites of action and nature of the inhibitory effect.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Drug Antagonism; Drug Synergism; Enzymes; Esterases; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Nalorphine; Narcotic Antagonists; Procaine; Spectrophotometry

1966
[Modifications of the contractility of the sphincter of Oddi under the influence of central analgesics].
    Revue internationale d'hepatologie, 1967, Volume: 17, Issue:1

    Topics: Ampulla of Vater; Amyl Nitrite; Atropine; Chlorpromazine; Cholecystectomy; Humans; Hydromorphone; Meperidine; Methadone; Procaine

1967
A method of identifying narcotic analgesics in human urine after therapeutic doses.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Alkaloids; Analgesics; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Humans; Hydromorphone; Ion Exchange; Levorphanol; Meperidine; Methadone; Methods; Morphine; Narcotics; Pentazocine

1970
[Permeation of active morphine-like substances at their sites of antinociceptive action in the brain as a function of their lipid-solubility following intravenous and intraventricular application].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:5

    Topics: Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Dental Pulp Test; Fentanyl; Hydromorphone; Ketones; Kinetics; Levorphanol; Lipids; Methadone; Morphinans; Morphine; Piperidines; Rabbits; Solubility; Tritium

1970
Application of enzyme kinetics to a problem in pharmacology: receptor affinities and efficacies in the action of morphine and related drugs on human serum esterase.
    Enzymologia, 1970, May-31, Volume: 38, Issue:5

    Topics: Esterases; Hydromorphone; Kinetics; Levorphanol; Mathematics; Metabolism; Methadone; Morphine; Nalorphine

1970
Three-choice discrimination in methadone maintenance patients: hydromorphone, naloxone, and saline.
    NIDA research monograph, 1984, Volume: 55

    Topics: Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Humans; Hydromorphone; Male; Methadone; Naloxone; Substance-Related Disorders

1984
Opiates and thermoregulation in mice. I. Agonists.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone

1980
Clinical effects of parenteral narcotics in hospitalized medical patients.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Codeine; Drug Utilization; Female; Humans; Hydromorphone; Injections; Male; Methadone; Morphine; Narcotics; Opium

1980
Zinc tannate salts of heroin, LAAM and hydromorphone attenuate opiate withdrawal syndrome.
    Psychopharmacology, 1980, Volume: 68, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Codeine; Delayed-Action Preparations; Heroin; Humans; Hydromorphone; Male; Methadone; Methadyl Acetate; Opioid-Related Disorders; Rats; Substance Withdrawal Syndrome; Zinc

1980
Comparison of the effects of buprenorphine and methadone on opiate self-administration in primates.
    NIDA research monograph, 1982, Volume: 41

    Topics: Animals; Buprenorphine; Dose-Response Relationship, Drug; Eating; Heroin Dependence; Humans; Hydromorphone; Macaca mulatta; Macaca nemestrina; Male; Methadone; Morphinans; Opioid-Related Disorders; Self Administration

1982
Comparison of buprenorphine and methadone effects on opiate self-administration in primates.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2

    Topics: Animals; Buprenorphine; Depression, Chemical; Disease Models, Animal; Feeding Behavior; Heroin; Humans; Hydromorphone; Macaca mulatta; Macaca nemestrina; Methadone; Morphinans; Opioid-Related Disorders; Self Administration

1983
Intravenous hydromorphone: effects in opiate-free and methadone maintenance subjects.
    NIDA research monograph, 1983, Volume: 43

    Topics: Adult; Blood Pressure; Heart Rate; Humans; Hydromorphone; Injections, Intravenous; Male; Methadone; Opioid-Related Disorders; Pupil; Respiration; Skin Temperature

1983
Use of methadone in a highly tolerant patient receiving parenteral hydromorphone.
    Journal of pain and symptom management, 1995, Volume: 10, Issue:4

    Topics: Breast Neoplasms; Drug Costs; Drug Tolerance; Female; Humans; Hydromorphone; Infusions, Parenteral; Methadone; Middle Aged; Palliative Care

1995
Opioid rotation in patients with cancer pain. A retrospective comparison of dose ratios between methadone, hydromorphone, and morphine.
    Cancer, 1996, Aug-15, Volume: 78, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hydromorphone; Injections, Subcutaneous; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Retrospective Studies

1996
Individualized use of methadone and opioid rotation in the comprehensive management of cancer pain associated with poor prognostic indicators.
    Pain, 1996, Volume: 67, Issue:1

    Topics: Carcinoma, Renal Cell; Drug Administration Schedule; Humans; Hydromorphone; Kidney Neoplasms; Male; Methadone; Middle Aged; Narcotics; Pain; Palliative Care; Prognosis; Spinal Neoplasms

1996
Intravenous methadone for cancer pain unrelieved by morphine and hydromorphone: clinical observations.
    Pain, 1997, Volume: 70, Issue:1

    Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Hydromorphone; Injections, Intravenous; Male; Methadone; Morphine; Pain; Palliative Care; Peritoneal Neoplasms; Retreatment; Stomach Neoplasms

1997
Equianalgesic dose/ratio between methadone and other opioid agonists in cancer pain: comparison of two clinical experiences.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Linear Models; Male; Methadone; Middle Aged; Neoplasms; Pain; Receptors, Opioid; Retrospective Studies

1998
Hydromorphone-naloxone combinations in opioid-dependent humans under a naloxone novel-response discrimination procedure.
    Experimental and clinical psychopharmacology, 1998, Volume: 6, Issue:2

    Topics: Adult; Discrimination Learning; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Male; Methadone; Naloxone; Opioid-Related Disorders

1998
Comment on Manfredi et al.,Pain, 70 (1997) 199-101.
    Pain, 1998, Volume: 77, Issue:1

    Topics: Analgesics, Opioid; Humans; Hydromorphone; Injections, Intravenous; Methadone; Morphine; Neoplasms; Palliative Care; Retreatment

1998
The relationship between the visual analog pain intensity and pain relief scale changes during analgesic drug studies in chronic pain patients.
    Anesthesiology, 1999, Volume: 91, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Chronic Disease; Female; Humans; Hydromorphone; Male; Methadone; Middle Aged; Pain; Pain Measurement; Regression Analysis

1999
[Opioids. Pharmacology, clinic, prospectives for an extensive use].
    Recenti progressi in medicina, 2000, Volume: 91, Issue:12

    Topics: Analgesics, Opioid; Codeine; Drug Tolerance; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Oxycodone; Receptors, Opioid; Tramadol

2000
Morphine and alternative opioids in cancer pain: the EAPC recommendations.
    British journal of cancer, 2001, Mar-02, Volume: 84, Issue:5

    Topics: Administration, Oral; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Administration Schedule; Fentanyl; Humans; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Injections, Subcutaneous; Methadone; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care

2001
Using saccadic eye movements as objective measures of tolerance in methadone dependent individuals during the hydromorphone challenge test.
    Addiction biology, 2003, Volume: 8, Issue:1

    Topics: Adult; Drug Tolerance; Female; Humans; Hydromorphone; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Saccades

2003
The chemistry of drugs of addiction.
    The American journal of medicine, 1953, Volume: 14, Issue:5

    Topics: Barbiturates; Cannabis; Humans; Hydromorphone; Meperidine; Methadone; Morphine Derivatives

1953
[Behavior modifiers inthe study of bile ducts. (Combined action of morphine substances and cholecystokinin)].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1963, Volume: 44

    Topics: Ampulla of Vater; Bile Ducts; Cholecystokinin; Codeine; Dextromoramide; Hydromorphone; Meperidine; Methadone; Morphine; Opium

1963
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS.
    Wisconsin medical journal, 1964, Volume: 63

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pain; Phenazocine; Piperidines

1964
BARBITURATE USE IN NARCOTIC ADDICTS.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine Dependence; Narcotics; Opium; Pentobarbital; Seizures; Statistics as Topic; Substance-Related Disorders; Toxicology; Urea

1964
A RAPID SCREENING TEST FOR POTENTIAL ADDICTION LIABILITY OF NEW ANALGESIC AGENTS.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior, Addictive; Codeine; Dextropropoxyphene; Heroin; Hydromorphone; Meperidine; Methadone; Mice; Morphine; Phenazocine; Research; Substance-Related Disorders; Toxicology

1964
RELATIVE POTENCY OF CODEINE, METHADONE AND DIHYDROMORPHINONE TO MORPHINE IN SELF-MAINTAINED ADDICT RATS.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Jan-08, Volume: 249

    Topics: Codeine; Hydromorphone; Methadone; Morphine; Morphine Dependence; Periodicity; Pharmacology; Rats; Research

1965
Successful treatment of hydromorphone-induced neurotoxicity and hyperalgesia.
    Connecticut medicine, 2004, Volume: 68, Issue:9

    Topics: Humans; Hydromorphone; Hyperalgesia; Male; Methadone; Middle Aged; Narcotics; Neurotoxicity Syndromes; Pain

2004
Rotation to methadone after opioid dose escalation: How should individualization of dosing occur?
    Journal of pain & palliative care pharmacotherapy, 2005, Volume: 19, Issue:2

    Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Methadone; Middle Aged; Neoplasms; Neurotoxicity Syndromes; Pain, Intractable; Palliative Care

2005
Anesthesia and pain management for pediatric patients with dystrophic epidermolysis bullosa.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:4

    Topics: Adolescent; Anesthesia, General; Child; Child, Preschool; Conscious Sedation; Epidermolysis Bullosa Dystrophica; Female; Humans; Hydromorphone; Infant; Male; Methadone; Morphine; Pain; Perioperative Care; Postoperative Complications; Preoperative Care; Retrospective Studies

2006
Equianalgesic dosing of opioids.
    Journal of pain & palliative care pharmacotherapy, 2006, Volume: 20, Issue:4

    Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Fentanyl; Humans; Hydromorphone; Methadone; Pain; Therapeutic Equivalency

2006
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
    Anesthesiology, 2007, Volume: 106, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroin; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Male; Methadone; Morphine; Neuralgia; Pain; Rats; Rats, Inbred F344; Self Administration

2007
Behavioral economic analysis of drug preference using multiple choice procedure data.
    Drug and alcohol dependence, 2008, Jan-11, Volume: 93, Issue:1-2

    Topics: Choice Behavior; Economics; Fentanyl; Fluoxetine; Hallucinogens; Humans; Hydromorphone; Injections, Intramuscular; Methadone; Models, Psychological; Motivation; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Narcotics; Psychotropic Drugs; Recreation; Selective Serotonin Reuptake Inhibitors; Substance Abuse, Intravenous; Substance-Related Disorders

2008
Use of methadone to combat withdrawal symptoms of dilaudid addiction; case report.
    The Journal of the Tennessee State Medical Association. Tennessee State Medical Association, 1949, Volume: 42, Issue:3

    Topics: Behavior, Addictive; Drug-Related Side Effects and Adverse Reactions; Humans; Hydromorphone; Methadone; Substance Withdrawal Syndrome; Substance-Related Disorders

1949
The underrecognized toll of prescription opioid abuse on young children.
    Annals of emergency medicine, 2009, Volume: 53, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Buprenorphine; Child, Preschool; Female; Humans; Hydrocodone; Hydromorphone; Infant; Infant, Newborn; Male; Methadone; Morphine; Oxycodone; Poisoning; Prescription Drugs; United States

2009
Rewarding electrical brain stimulation in rats after peripheral nerve injury: decreased facilitation by commonly abused prescription opioids.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Adenosine; Amines; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hydromorphone; Injections, Spinal; Male; Methadone; Oxycodone; Peripheral Nerve Injuries; Rats; Rats, Inbred F344; Reward

2011
Prescription opioid misuse: characteristics of earliest and most recent memory of hydromorphone use.
    Journal of addiction medicine, 2012, Volume: 6, Issue:2

    Topics: Adult; Analgesics, Opioid; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Utilization; Female; Humans; Hydromorphone; Male; Mental Recall; Methadone; Middle Aged; Motivation; Narcotics; Nova Scotia; Opioid-Related Disorders; Prescription Drugs

2012
Transitioning a cancer patient from high-dose intravenous hydromorphone therapy to intravenous methadone.
    Journal of pain & palliative care pharmacotherapy, 2011, Volume: 25, Issue:4

    Topics: Adult; Analgesics, Opioid; Colorectal Neoplasms; Fatal Outcome; Female; Humans; Hydromorphone; Infusions, Intravenous; Methadone; Neoplasm Metastasis; Pain; Palliative Care

2011
What is your gut feeling about opioid rotation?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jan-20, Volume: 33, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Biological Availability; Delayed-Action Preparations; Drug Administration Schedule; Fentanyl; Humans; Hydromorphone; Intestinal Obstruction; Male; Methadone; Middle Aged; Morphine; Neoplasms; Pain; Pain Management; Quality of Life

2015
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Methadone Use and the Risk of Hypoglycemia for Inpatients With Cancer Pain.
    Journal of pain and symptom management, 2016, Volume: 51, Issue:1

    Topics: Adult; Aged; Analgesics, Opioid; Blood Glucose; Cancer Pain; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Hypoglycemia; Incidence; Inpatients; Male; Methadone; Middle Aged; Retrospective Studies; Risk; Time Factors

2016
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
    Journal of analytical toxicology, 2016, Volume: 40, Issue:8

    Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine

2016
Interpretation of Urine Drug Screens: Metabolites and Impurities.
    JAMA, 2017, Nov-07, Volume: 318, Issue:17

    Topics: Analgesics, Opioid; Codeine; False Positive Reactions; Female; Humans; Hydromorphone; Immunoassay; Mass Spectrometry; Methadone; Middle Aged; Morphine; Substance Abuse Detection

2017
Cost-effectiveness of hydromorphone for severe opioid use disorder: findings from the SALOME randomized clinical trial.
    Addiction (Abingdon, England), 2018, Volume: 113, Issue:7

    Topics: British Columbia; Cost-Benefit Analysis; Crime; Double-Blind Method; Equivalence Trials as Topic; Health Services; Heroin; Hospitalization; Humans; Hydromorphone; Methadone; Mortality; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Severity of Illness Index

2018
Commentary on Bansback et al. (2018): Estimating the cost of stigma against injection.
    Addiction (Abingdon, England), 2018, Volume: 113, Issue:7

    Topics: Cost-Benefit Analysis; Heroin; Humans; Hydromorphone; Methadone; Opioid-Related Disorders

2018
Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report.
    A&A practice, 2019, Jan-15, Volume: 12, Issue:2

    Topics: Analgesics, Opioid; Colonic Pseudo-Obstruction; Constipation; Decompression, Surgical; Humans; Hydromorphone; Intestinal Perforation; Low Back Pain; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Postoperative Complications; Quaternary Ammonium Compounds; Spinal Stenosis

2019
Implementation of a Risk-Stratified Opioid and Benzodiazepine Weaning Protocol in a Pediatric Cardiac ICU.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018, Volume: 19, Issue:11

    Topics: Analgesics, Opioid; Benzodiazepines; Cardiovascular Diseases; Female; Humans; Hydromorphone; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Length of Stay; Lorazepam; Male; Methadone; Prospective Studies; Risk Assessment; Severity of Illness Index; Substance Withdrawal Syndrome

2018
Glutathione and Glutathione-Like Sequences of Opioid and Aminergic Receptors Bind Ascorbic Acid, Adrenergic and Opioid Drugs Mediating Antioxidant Function: Relevance for Anesthesia and Abuse.
    International journal of molecular sciences, 2020, Aug-28, Volume: 21, Issue:17

    Topics: Analgesics, Opioid; Ascorbic Acid; Dehydroascorbic Acid; Enkephalin, Methionine; Glutathione; Humans; Hydromorphone; Methadone; Morphine; Naloxone; Peptides; Receptors, Adrenergic, beta-2; Receptors, Dopamine D1; Receptors, Histamine H1; Receptors, Opioid; Receptors, Opioid, mu

2020
Hydromorphone and codeine concentrations in oral fluid specimens from patients receiving substitution therapy with Substitol™ (morphine sulfate).
    Drug testing and analysis, 2021, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Buprenorphine; Codeine; Female; Humans; Hydromorphone; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Saliva; Substance Abuse Detection

2021
Tapentadol in Cancer Patients with Neuropathic Pain: A Comparison of Methadone, Oxycodone, Fentanyl, and Hydromorphone.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Hydromorphone; Japan; Male; Methadone; Middle Aged; Neoplasms; Neuralgia; Oxycodone; Pain Measurement; Retrospective Studies; Tapentadol

2021
Declines and regional variation in opioid distribution by U.S. hospitals.
    Pain, 2022, 06-01, Volume: 163, Issue:6

    Topics: Analgesics, Opioid; Buprenorphine; Codeine; Hospitals; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Oxymorphone; United States

2022
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases.
    Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8

    Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem

2022
Scheduled methadone reduces overall opioid requirements after pediatric posterior spinal fusion: A single center retrospective case series.
    Paediatric anaesthesia, 2022, Volume: 32, Issue:10

    Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Child; Humans; Hydromorphone; Methadone; Pain, Postoperative; Retrospective Studies; Scoliosis; Spinal Fusion

2022
Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns.
    JAMA network open, 2022, 08-01, Volume: 5, Issue:8

    Topics: Adult; Analgesics, Opioid; Codeine; Cohort Studies; Female; Humans; Hydrocodone; Hydromorphone; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine; Neonatal Abstinence Syndrome; Oxycodone; Pain; Pregnancy; Prescriptions; Substance Withdrawal Syndrome; Tramadol; United States

2022
Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder.
    Addiction science & clinical practice, 2023, 02-24, Volume: 18, Issue:1

    Topics: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Female; Humans; Hydromorphone; Male; Methadone; Naloxone; Opiate Substitution Treatment; Opioid-Related Disorders; Pain

2023
[Drug therapy for cancer-related pain-evidence regarding hydromorphone, oxycodone, and methadone : Presentation and summary of three Cochrane reviews].
    Urologie (Heidelberg, Germany), 2023, Volume: 62, Issue:6

    Topics: Analgesics, Opioid; Cancer Pain; Humans; Hydromorphone; Methadone; Neoplasms; Oxycodone

2023