hydromorphone has been researched along with hydromorphone-3-glucuronide in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Babul, N; Darke, AC; Dhaliwal, HS; Hagen, N; Harsanyi, Z; Thirlwell, MP | 1 |
| Nocente, ML; Smith, MT; Wright, AW | 1 |
| Mather, LE; Smith, MT; Wright, AW | 1 |
| McErlane, KM; Ong, MC; Zheng, M | 3 |
| Lee, C; Meatherall, R; Phillips, S | 1 |
| Kullgren, J; Le, V; Wheeler, W | 1 |
| Franc, MA; Francke, S; Lu, CC; Richards, H; Van Den Bergh, A; Vandenbossche, J | 1 |
| Ishizuka, H; Kobayashi, S; Sambe, T; Toyama, K; Uchida, N | 1 |
| Bynum, ND; Flegel, R; Grabenauer, M; Hayes, ED; Mitchell, JM; Moore, KN; White, RM | 1 |
| Backman, JT; Lilius, TO; Lohela, TJ; Neuvonen, M; Niemi, M; Olkkola, KT; Poikola, S | 1 |
| Hawkins, MG; Knych, HK; Sanchez-Migallon Guzman, D; Sosa-Higareda, M | 1 |
4 trial(s) available for hydromorphone and hydromorphone-3-glucuronide
| Article | Year |
|---|---|
Steady-state pharmacokinetics of hydromorphone and hydromorphone-3-glucuronide in cancer patients after immediate and controlled-release hydromorphone.
Topics: Administration, Oral; Biological Availability; Delayed-Action Preparations; Double-Blind Method; Female; Glucuronates; Humans; Hydromorphone; Male; Middle Aged; Neoplasms; Pain Management; Retrospective Studies | 1995 |
The effect of UGT2B7*2 polymorphism on the pharmacokinetics of OROS® hydromorphone in Taiwanese subjects.
Topics: Adult; Analgesics, Opioid; Area Under Curve; Asian People; Delayed-Action Preparations; Female; Genotype; Glucuronates; Glucuronosyltransferase; Humans; Hydromorphone; Male; Naltrexone; Polymorphism, Genetic; Taiwan; Young Adult | 2014 |
Single-dose evaluation of safety, tolerability and pharmacokinetics of newly formulated hydromorphone immediate-release and hydrophilic matrix extended-release tablets in healthy Japanese subjects without co-administration of an opioid antagonist.
Topics: Adult; Analgesics, Opioid; Area Under Curve; Asian People; Cross-Over Studies; Delayed-Action Preparations; Drug Therapy, Combination; Food-Drug Interactions; Glucuronates; Half-Life; Humans; Hydromorphone; Male; Middle Aged; Young Adult | 2015 |
Rifampin Reduces the Plasma Concentrations of Oral and Intravenous Hydromorphone in Healthy Volunteers.
Topics: Administration, Intravenous; Administration, Oral; Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Double-Blind Method; Drug Interactions; Female; Finland; Glucuronates; Healthy Volunteers; Humans; Hydromorphone; Inactivation, Metabolic; Male; Rifampin; Young Adult | 2021 |
9 other study(ies) available for hydromorphone and hydromorphone-3-glucuronide
| Article | Year |
|---|---|
Hydromorphone-3-glucuronide: biochemical synthesis and preliminary pharmacological evaluation.
Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Dyskinesia, Drug-Induced; Gas Chromatography-Mass Spectrometry; Glucuronates; Hydromorphone; Injections, Intraventricular; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Motor Activity; Rats; Rats, Sprague-Dawley; Seizures; Uridine Diphosphate Glucuronic Acid | 1998 |
Hydromorphone-3-glucuronide: a more potent neuro-excitant than its structural analogue, morphine-3-glucuronide.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Glucuronates; Hydromorphone; Injections, Intraventricular; Male; Morphine Derivatives; Motor Activity; Rats; Rats, Sprague-Dawley | 2001 |
LC-MS-MS analysis of hydromorphone and hydromorphone metabolites with application to a pharmacokinetic study in the male Sprague-Dawley rat.
Topics: Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Glucuronates; Hydromorphone; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley | 2002 |
Hydromorphone metabolites: isolation and identification from pooled urine samples of a cancer patient.
Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Dihydromorphine; Female; Glucuronates; Glucuronides; Humans; Hydromorphone; Mass Spectrometry; Molecular Structure; Neoplasms | 2002 |
Identification and synthesis of norhydromorphone, and determination of antinociceptive activities in the rat formalin test.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Chromatography, Liquid; Glucuronates; Humans; Hydromorphone; Mass Spectrometry; Pain Measurement; Rats; Time Factors | 2004 |
Accidental death from hydromorphone ingestion.
Topics: Accidents; Adolescent; Bronchopneumonia; Forensic Toxicology; Glucuronates; Humans; Hydromorphone; Hypoxia-Ischemia, Brain; Male; Narcotics; Pulmonary Edema; Respiratory Aspiration; Vitreous Body | 2011 |
Incidence of hydromorphone-induced neuroexcitation in hospice patients.
Topics: Aged; Analgesics, Opioid; Female; Glucuronates; Hospice Care; Humans; Hydromorphone; Incidence; Kidney Function Tests; Male; Neurotoxicity Syndromes; Nevada; Prospective Studies; Risk Factors | 2013 |
Detection and quantification of codeine-6-glucuronide, hydromorphone-3-glucuronide, oxymorphone-3-glucuronide, morphine 3-glucuronide and morphine-6-glucuronide in human hair from opioid users by LC-MS-MS.
Topics: Chromatography, Liquid; Codeine; Glucuronates; Hair; Humans; Hydromorphone; Limit of Detection; Morphine Derivatives; Opioid-Related Disorders; Reproducibility of Results; Specimen Handling; Substance Abuse Detection; Tandem Mass Spectrometry | 2018 |
High bioavailability, short half-life, and metabolism into hydromorphone-3-glucuronide following single intramuscular and intravenous administration of hydromorphone hydrochloride to great horned owls (Bubo virginianus).
Topics: Administration, Intravenous; Animals; Area Under Curve; Biological Availability; Female; Half-Life; Hydromorphone; Injections, Intramuscular; Injections, Intravenous; Male; Mammals; Strigiformes | 2023 |