Compounds > hydromorphone

hydromorphone and enkephalin, leucine

hydromorphone has been researched along with enkephalin, leucine in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (75.00)	18.7374
1990's	2 (16.67)	18.2507
2000's	1 (8.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Archer, S; Bidlack, JM; Jiang, Q; Seyed-Mozaffari, A	2
Goodman, RR; Hahn, EF; Nishimura, S; Pasternak, GW	1
Hahn, EF; Itzhak, Y; Johnson, N; Nishimura, S; Pasternak, GW	1
Galetta, S; Hahn, EF; Nishimura, S; Pasternak, GW	1
Larson, DL; Lemieux, C; Nguyen, TM; Portoghese, PS; Ronsisvalle, G; Schiller, PW; Takemori, AE	1
Bodnar, RJ; Burks, TF; Clark, JE; Hahn, EF; Pasternak, GW; Williams, CL	1
Bowen, WD; Herkenham, M; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Chang, KJ; Cuatrecasas, P; Hazum, E; Leighton, HJ; Lever, OW	1
Giles, T; Merz, H; Sander, G	1
Burke, TR; Danks, JA; Jacobson, AE; Pert, CB; Rice, KC; Rothman, RB	1
Bonney, IM; Carr, DB; Hasirci, V; Lipkowski, AW; Sendil, D; Wise, DL	1

Other Studies

12 other study(ies) available for hydromorphone and enkephalin, leucine

Article	Year
Antinociceptive properties of two alkylating derivatives of morphinone: 14 beta-(thioglycolamido)-7,8-dihydromorphinone (TAMO) and 14 beta-(bromoacetamido)-7,8-dihydromorphinone (H2BAMO). The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2 Topics: Analgesics; Animals; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydromorphone; Male; Mice; Mice, Inbred ICR; Opioid-Related Disorders; Receptors, Opioid; Receptors, Opioid, mu	1992
Irreversible opiate agonists and antagonists. II. Evidence against a bivalent mechanism of action for opiate azines and diacylhydrazones. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Animals; Binding, Competitive; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship	1985
Irreversible opiate agonists and antagonists. III. Phenylhydrazone derivatives of naloxone and oxymorphone. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3 Topics: Albumins; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship; Tritium	1985
Oxymorphone-naltrexonazine, a mixed opiate agonist-antagonist. Life sciences, 1987, Aug-10, Volume: 41, Issue:6 Topics: Analgesia; Animals; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; Male; Mice; Mice, Inbred ICR; Naltrexone; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium	1987
Hybrid bivalent ligands with opiate and enkephalin pharmacophores. Journal of medicinal chemistry, 1987, Volume: 30, Issue:11 Topics: Analgesics; Animals; Enkephalins; Guinea Pigs; Hydromorphone; Ligands; Male; Mice; Muscle, Smooth; Naloxone; Oxymorphone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu	1987
Irreversible opiate agonists and antagonists. IV. Analgesic actions of 14-hydroxydihydromorphinone hydrazones. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1 Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrazones; Hydromorphone; Male; Mice; Naloxone; Oxymorphone; Receptors, Opioid; Time Factors	1988
A quantitative study of [3H]D-Ala2-D-Leu5-enkephalin binding to rat brain membranes. Evidence that oxymorphone is a noncompetitive inhibitor of the lower affinity delta-binding site. Molecular pharmacology, 1985, Volume: 27, Issue:3 Topics: Animals; Autoradiography; Brain; Chlorides; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guanosine Triphosphate; Hydromorphone; Male; Manganese; Manganese Compounds; Mathematics; Membranes; Oligopeptides; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride	1985
Increased biological activity of dimers of oxymorphone and enkephalin: possible role of receptor crosslinking. Biochemical and biophysical research communications, 1982, Jan-15, Volume: 104, Issue:1 Topics: Animals; Binding, Competitive; Biological Assay; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Endorphins; Enkephalins; Guinea Pigs; Hydromorphone; Ileum; Kinetics; Muscle Contraction; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship	1982
Quaternary opiate antagonists lower blood pressure and inhibit leucine-enkephalin responses. European journal of pharmacology, 1983, Nov-25, Volume: 95, Issue:3-4 Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Enkephalin, Leucine; Heart Rate; Hydromorphone; Naloxone; Naltrexone; Oxymorphone; Quaternary Ammonium Compounds	1983
Tritiated-6-beta-fluoro-6-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding. Neuropeptides, 1984, Volume: 4, Issue:4 Topics: Animals; Benzomorphans; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Fentanyl; Hydromorphone; Isothiocyanates; Kinetics; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu; Thiocyanates; Tomography, Emission-Computed	1984
14 alpha,14' beta-[Dithiobis[(2-oxo-2,1-ethanediyl)imino]]bis (7,8-dihydromorphinone) and 14 alpha,14' beta-[dithiobis[(2-oxo-2,1- ethanediyl)imino]]bis[7,8-dihydro-N-(cyclopropylmethyl)normorphinone]: chemistry and opioid binding properties. Journal of medicinal chemistry, 1994, May-27, Volume: 37, Issue:11 Topics: Alkylation; Analgesics; Animals; Benzeneacetamides; Cattle; Cell Membrane; Corpus Striatum; Disulfides; Dithiothreitol; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydromorphone; Kinetics; Molecular Structure; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tosylphenylalanyl Chloromethyl Ketone	1994
Antinociceptive effects of hydromorphone, bupivacaine and biphalin released from PLGA polymer after intrathecal implantation in rats. Biomaterials, 2003, Volume: 24, Issue:11 Topics: Analgesics; Animals; Bupivacaine; Drug Delivery Systems; Drug Implants; Enkephalins; Hydromorphone; Injections, Spinal; Lactic Acid; Male; Pain; Pain Measurement; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley	2003