hydromorphone and codeine

hydromorphone has been researched along with codeine in 109 studies

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199045 (41.28)18.7374
1990's10 (9.17)18.2507
2000's17 (15.60)29.6817
2010's27 (24.77)24.3611
2020's10 (9.17)2.80

Authors

AuthorsStudies
Kotick, MP; Leland, DL2
Howes, JF; Kotick, MP; Osgood, PF; Polazzi, JO; Razdan, RK; Schut, RN; Villarreal, JE1
Bousquet, A; Howes, JF; Kotick, MP; Leland, DL; Polazzi, JO1
Bousquet, AR; Howes, JF; Kotick, MP; Leland, DL; Polazzi, JO1
Strassburg, CP; Tukey, RH1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Cone, EJ; Darwin, WD1
Kotick, MP; Leland, DL; Polazzi, JO; Schut, RN2
Pegelow, CH1
Bruce, NC; Gray Stephens, LD; Jordan, KN; Lowe, CR; Trebilcock, AE; Wilmot, CJ1
Sawynok, J1
Gorodetzky, CW1
Eddy, NB; May, EL1
Baden, MM; Huang, JC1
Terenius, L1
Bastos, ML; Jukofsky, D; Mulé, SJ1
Elliott, HW; Hine, CH; Nomof, N; Parker, KD1
Hug, CC1
Joshi, BC; Sargent, LJ1
Brown, SS; Clarke, RS; Dundee, JW; Hamilton, RC; Loan, WB; Morrison, JD1
Herz, A; Teschemacher, HJ; von Cube, B1
Röthig, J1
Fujimoto, JM; Wang, RI1
Herz, A; Hess, R; Teschemacher, H; von Cube, B1
Cochin, J; Miller, JM; Pelikan, EW; Rosow, CE1
Miller, RR1
Baskerville, JC; Brands, B; Gowdey, CW; Hirst, M1
Honigberg, IL; Stewart, JT1
Griesemer, EC; Nakamura, GR; Noguchi, TT; Park, JI1
Ghosh, AC; Herlihy, P; Howes, JF; Lavoie, RL; Razdan, RK1
Chi, CJ; Guo, YM; Liu, MQ; Zhu, CL1
Dietzen, DJ; Koenig, J; Turk, J1
Bruce, NC; Hailes, AM1
Archer, S; Bidlack, JM; Deecher, D; Glick, SD; Jiang, Q; Sebastian, A; Teitler, M1
Deitermann, D; Leikin, J; Lewis, D; Moore, CM1
Bruce, NC; French, CE; Hailes, AM; Rathbone, DA1
Manfredi, B; Mantegazza, P; Panerai, AE; Sacerdote, P1
Bruce, NC; French, CE; Hailes, AM; Long, MT; Rathbone, DA; Willey, DL1
Bohrer, A; Koenig, J; Nowatzke, W; Saunders, A; Turk, J; Zeng, J1
Arcuri, E; Centulio, F; Ciocca, F; D'Angiolino, G; Ginobbi, P; Marcelli, ME; Pelagalli, L; Tirelli, W1
Kakaiya, R; Wamhoff, J1
Jones, J; Moore, C; Tomlinson, K1
Hasirci, V; Sendil, D; Wise, DL1
Altunay, H; Hasirci, V; Sendil-Keskin, D; Wise, DL1
CHU, J1
BOEHME, H; HOCKE, H1
DU BOIS, R; PARIS, J; ROBELET, A; SALEHZIER, Y1
HOCH, W; JANITZKI, U; PAULUS, W1
PARIS, J; U BOIS, R; VANDENDORP, F1
CARPENTER, CL; DERBES, VJ; NEDER, GA; ZISKIND, MM1
MEYERSTEIN, AN1
DENGLER, AH; STAHNKE, HL1
WANG, RI1
HAMBURGER, E1
LASAGNA, L1
KOBAYASHI, S; SEKI, I; TAKAGI, H1
SHEMANO, I; WENDEL, H1
COLLINS, RJ; WEEKS, JR1
Hasirci, V; Keskin, DS; Wise, DL1
Bu, J; Jiang, Y; Ma, D; Shen, BH; Shen, M; Xiang, P; Zhuo, XY1
Friedrichsdorf, SJ; Kang, TI1
Gallagher, R1
HANDLEY, CA; HUGGINS, RA; LA FORGE, M1
Fowler, D; Jufer, RA; Levine, B; McDonough, PC; Vorce, S1
Bond, BS1
Bailey, FA; Burgio, KL; Durham, RM; Ferguson, L; Goode, PS; Redden, DT; Williams, BR; Woodby, LL1
Hunek, C; Jenkins, AJ; Lavins, ES1
Chronister, CW; Goldberger, BA; Merves, ML1
Dahn, T; Gunn, J; Kriger, S; Terrell, AR1
Gingras, M; Laberge, MH; Lefebvre, M1
ERCOLI, N; LEWIS, MN1
Alford, I; Shan, X; Tiscione, NB; Yeatman, DT1
Kahan, M; Mailis-Gagnon, A; Srivastava, A; Wilson, L1
Janecek, E; Kahan, M; Resnick, A; Sheehan, C; Srivastava, A; Wenghofer, EF; Wilson, L1
French, D; Lynch, K; Wu, A1
Black, DL; Cone, EJ; Flegel, RR; Heltsley, R; Lodico, CP; Mitchell, JM1
Atayee, RS; Best, BM; Ma, JD; Yee, DA1
Galanie, S; Smolke, CD; Thodey, K1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
Belford, M; Manicke, NE1
Black, DL; Cone, EJ; DePriest, AZ; Flegel, R; Heltsley, R; LoDico, C; Mitchell, JM1
ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B1
Darragh, A; Lee, LA; Marinova, M; Mastrianni, KR; Melendez, C; Ryan, E; Sitasuwan, P1
Blackmore, CC; Osborn, SR; Vasilyadis, M; Williams, B; Yu, J1
Baker, O; Garner, C; Nelson, LS; Poon, SJ; Rodgers, AF; Schuur, JD; Weiner, SG1
Bell, RF; Derry, S; Moore, RA; Wee, B; Wiffen, PJ1
Haymond, S; Heiman, H; Nagpal, G1
Bynum, ND; Flegel, R; Grabenauer, M; Hayes, ED; Mitchell, JM; Moore, KN; White, RM2
Bouillet, L; Gibod, IB; Greco, C; Khouri, C; Lepelley, M; Pralong, P; Rossignol, J1
Brooks-Lim, E; Chan, EYL; Jones, GR; Klein, KB; McDonald, BM; Svenson, LW1
Agüera, A; Campos-Mañas, MC; Ferrer, I; Sánchez Pérez, JA; Thurman, EM1
Brás, M; Fragoso, M; Vieira, C1
Abrams, R; Ambardekar, A; Kandil, E; Khan, A; Minhajuddin, A; Parikh, M; Williams, T1
Dani, M; Kennedy, D1
Austin, PC; Gomes, T; Juurlink, DN; Mamdani, M; Pang, A; Paterson, JM; Ray, JG; Zipursky, JS1
Beck, O; Böttcher, M; Keller, T; Lierheimer, S; Monticelli, FC1
Eidbo, SA; Hagedorn, JD; Kaufman, DE; Kropp Lopez, AK; Mathew, V; McCall, KL; Nichols, SD; Piper, BJ1
Coulter, C; Garnier, M; Moore, C1
Chau, A; Krausz, MR; Maclure, M; Nabavi, N; Polderman, S; Preston, R; Schwarz, SKW; Ziafat, K1
Bateman, BT; Esposito, DB; Hernández-Díaz, S; Huybrechts, KF; Mogun, H; Straub, L; Werler, MM1
Escher, M; Hentsch, L; Singovski, S; Xausa, G1
Bowie, AC; Brogly, SB; Camden, A; Guttmann, A; Li, W; Velez, MP; Werler, MM1

Reviews

11 review(s) available for hydromorphone and codeine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The therapeutic use of heroin: a review of the pharmacological literature.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:1

    Topics: Analgesia; Animals; Brain; Codeine; Depression; Euphoria; Female; Half-Life; Heroin; Humans; Hydromorphone; Kinetics; Liver; Male; Morphine; Morphine Derivatives; Neoplasms; Pain; Sex Factors; Solubility; Terminal Care; Water

1986
[Analgesics. 32].
    Pharmazeutische Praxis, 1969, Volume: 5

    Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine

1969
DRUG ADDICTION: A REVIEW.
    The Journal of school health, 1964, Volume: 34

    Topics: Adolescent; Amphetamine; Amphetamines; Barbiturates; Cannabis; Codeine; Heroin; Humans; Hydromorphone; Jurisprudence; Meperidine; Mescaline; Methadone; Morphine Dependence; Nalorphine; Narcotic Antagonists; Psychotherapy; Statistics as Topic; Substance-Related Disorders

1964
THE CLINICAL EVALUATION OF MORPHINE AND ITS SUBSTITUTES AS ANALGESICS.
    Pharmacological reviews, 1964, Volume: 16

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Meperidine; Methadone; Methotrimeprazine; Morphine; Nalorphine; Narcotic Antagonists; Oxymorphone; Pentazocine; Phenazocine; Substance-Related Disorders; Toxicology

1964
The management of pain in children with life-limiting illnesses.
    Pediatric clinics of North America, 2007, Volume: 54, Issue:5

    Topics: Analgesics, Opioid; Child; Chronic Disease; Codeine; Fentanyl; Humans; Hydromorphone; Ketamine; Methadone; Morphine; Nociceptors; Oxycodone; Pain; Pain Measurement; Severity of Illness Index

2007
Equianalgesia: applying evidence-based practice guidelines.
    Clinical journal of oncology nursing, 2008, Volume: 12, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Codeine; Drug Monitoring; Evidence-Based Medicine; Humans; Hydromorphone; Methadone; Morphine; Neoplasms; Nurse's Role; Nursing Assessment; Oncology Nursing; Pain; Practice Guidelines as Topic; Therapeutic Equivalency; Treatment Outcome

2008
Opioids for cancer pain - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2017, 07-06, Volume: 7

    Topics: Acetaminophen; Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Fentanyl; Humans; Hydromorphone; Methadone; Oxycodone; Phenols; Review Literature as Topic; Tapentadol; Tramadol

2017
[Opioids for Cancer Pain and its Use under Particular Conditions: A Narrative Review].
    Acta medica portuguesa, 2019, May-31, Volume: 32, Issue:5

    Topics: Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Deglutition Disorders; Fentanyl; Humans; Hydromorphone; Liver Failure; Morphine; Oxycodone; Renal Dialysis; Renal Insufficiency; Tapentadol; Tramadol

2019
Recurrent Persistent Hiccups on Opioid Treatment: A Case Report and Literature Review.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Analgesics, Opioid; Codeine; Hiccup; Humans; Hydromorphone; Male; Middle Aged; Morphine; Neoplasms; Pain

2023

Trials

3 trial(s) available for hydromorphone and codeine

ArticleYear
Studies of drugs given before anaesthesia. XVII: The natural and semi-synthetic opiates.
    British journal of anaesthesia, 1969, Volume: 41, Issue:1

    Topics: Clinical Trials as Topic; Codeine; Female; Heroin; Humans; Hydromorphone; Morphine; Oxymorphone; Placebos; Preanesthetic Medication

1969
Prescription opioids. II. Metabolism and excretion patterns of hydrocodone in urine following controlled single-dose administration.
    Journal of analytical toxicology, 2013, Volume: 37, Issue:8

    Topics: Administration, Oral; Adult; Analgesics, Opioid; Chromatography, Liquid; Codeine; Creatinine; Female; Humans; Hydrocodone; Hydrolysis; Hydromorphone; Limit of Detection; Male; Metabolic Clearance Rate; Prescription Drug Misuse; Substance Abuse Detection; Tandem Mass Spectrometry; Tissue Distribution; Young Adult

2013
Prescription Opioids. IV: Disposition of Hydrocodone in Oral Fluid and Blood Following Single-Dose Administration.
    Journal of analytical toxicology, 2015, Volume: 39, Issue:7

    Topics: Analgesics, Opioid; Biotransformation; Chromatography, Liquid; Codeine; Healthy Volunteers; Humans; Hydrocodone; Hydromorphone; Limit of Detection; Predictive Value of Tests; Prescription Drugs; Reproducibility of Results; Saliva; Tandem Mass Spectrometry; Tissue Distribution

2015

Other Studies

95 other study(ies) available for hydromorphone and codeine

ArticleYear
Analgesic narcotic antagonists. 5. 7,7-Dimethyldihydrocodeinones and 7,7-dimethyldihydromorphinones.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:6

    Topics: Analgesics, Opioid; Animals; Codeine; Hydrocodone; Hydromorphone; Mice; Narcotic Antagonists; Rats; Structure-Activity Relationship

1981
Analgesic narcotic antagonists. 2. 8-Alkymorphinan-6-ones.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:2

    Topics: Acetates; Analgesics; Animals; Haplorhini; Humans; Mice; Morphinans; Morphine Dependence; Narcotic Antagonists; Rats; Reaction Time; Structure-Activity Relationship; Substance Withdrawal Syndrome; Substance-Related Disorders

1980
Analgesic narcotic antagonists. 15. Potent narcotic agonist 7 beta-(arylalkyl)-4,5 alpha-epoxymorphinans.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:7

    Topics: Analgesics; Indicators and Reagents; Morphinans; Narcotic Antagonists; Structure-Activity Relationship

1983
Analgesic narcotic antagonists. 4. 7-Methyl-N-(cycloalkylmethyl)-3-hydroxymorphinan-6-ones and -isomorphinan-6-ones.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:12

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Humans; Morphinans; Morphine Dependence; Narcotic Antagonists; Substance Withdrawal Syndrome

1980
Analgesic narcotic antagonists. 8. 7 alpha-Alkyl-4,5 alpha-epoxymorphinan-6-ones.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:12

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Hydrocodone; In Vitro Techniques; Mice; Narcotic Antagonists; Rats; Reaction Time

1981
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
Simultaneous determination of hydromorphone, hydrocodone and their 6alpha- and 6beta-hydroxy metabolites in urine using selected ion recording with methane chemical ionization.
    Biomedical mass spectrometry, 1978, Volume: 5, Issue:4

    Topics: Codeine; Humans; Hydrocodone; Hydromorphone; Mass Spectrometry; Methane

1978
8 beta-alkyl-N-cycloalkyl-dihydro-codeinones and -morphinones as analgesic narcotic antagonists.
    NIDA research monograph, 1979, Volume: 27

    Topics: Codeine; Hydrocodone; Hydromorphone; Narcotic Antagonists

1979
Survey of pain management therapy provided for children with sickle cell disease.
    Clinical pediatrics, 1992, Volume: 31, Issue:4

    Topics: Acetaminophen; Analgesics; Anemia, Sickle Cell; Child; Child, Preschool; Codeine; Drug Administration Schedule; Drug Combinations; Humans; Hydromorphone; Infant; Length of Stay; Meperidine; Morphine; Nalbuphine; Pain; Pain Management; Seizures

1992
Microbial degradation of the morphine alkaloids: identification of morphine as an intermediate in the metabolism of morphine by Pseudomonas putida M10.
    Archives of microbiology, 1990, Volume: 154, Issue:5

    Topics: Biodegradation, Environmental; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Hydromorphone; Magnetic Resonance Spectroscopy; Molecular Structure; Morphine; NADPH Dehydrogenase; Oxidation-Reduction; Pseudomonas; Thebaine

1990
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine

1972
The search for a better analgesic.
    Science (New York, N.Y.), 1973, Aug-03, Volume: 181, Issue:4098

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Heroin; Humans; Hydromorphone; Levorphanol; Meperidine; Methadone; Morphinans; Morphine Dependence; Structure-Activity Relationship

1973
Rapid methods of screening micro-quantities of abused drugs from urine samples for microcrystal tests.
    Clinical toxicology, 1973, Volume: 6, Issue:3

    Topics: Acids; Alkalies; Alkaloids; Chromatography, Thin Layer; Codeine; Crystallization; Crystallography; Heroin Dependence; Humans; Hydromorphone; Indicators and Reagents; Meperidine; Methadone; Methods; Morphine; Nicotine; Quinine; Substance-Related Disorders

1973
Stereospecific uptake of narcotic analgesics by a subcellular fraction of the guinea-pig ileum. A preliminary communication.
    Upsala journal of medical sciences, 1973, Volume: 78, Issue:3

    Topics: Analgesics; Animals; Codeine; Dextromoramide; Female; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Intestinal Absorption; Levorphanol; Male; Methadone; Morphine; Muscle, Smooth; Nalorphine; Naloxone; Narcotics; Subcellular Fractions; Tritium

1973
Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse.
    Clinical chemistry, 1974, Volume: 20, Issue:2

    Topics: Amphetamine; Apomorphine; Barbiturates; Chromatography, Thin Layer; Cocaine; Codeine; Cross Reactions; Cyclazocine; Dextromethorphan; Dextropropoxyphene; Evaluation Studies as Topic; Hemagglutination Inhibition Tests; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Radioimmunoassay; Spectrometry, Fluorescence; Substance-Related Disorders; Time Factors; Tritium

1974
Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test.
    Journal of forensic sciences, 1966, Volume: 11, Issue:2

    Topics: Amphetamine; California; Cocaine; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Nalorphine; Pupil; Substance-Related Disorders

1966
Transport of narcotic analgesics by choroid plexus and kidney tissue in vitro.
    Biochemical pharmacology, 1967, Volume: 16, Issue:2

    Topics: Analgesics; Animals; Atmospheric Pressure; Biological Transport, Active; Carbon Isotopes; Choroid Plexus; Chromatography, Paper; Codeine; Dogs; Female; Hexamethonium Compounds; Hydrogen-Ion Concentration; Hydromorphone; In Vitro Techniques; Insulin; Kidney; Levorphanol; Male; Morphine; Nalorphine; Nitrogen; Oxygen; Probenecid; Rabbits; Temperature; Tritium

1967
Transformations in the morphine series. II. A new position isomer of dihydromorphinone.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:2

    Topics: Analgesics; Animals; Codeine; Hydromorphone; Infrared Rays; Mice; Optical Rotatory Dispersion; Spectrophotometry

1968
[A comparison of the analgetic action of intravenously and intraventricularly injected morphine-like substances, taking into account their fat solubility].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:1

    Topics: Animals; Codeine; Hydromorphone; Lipids; Morphinans; Morphine; Rabbits; Solubility

1969
A method of identifying narcotic analgesics in human urine after therapeutic doses.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Alkaloids; Analgesics; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Humans; Hydromorphone; Ion Exchange; Levorphanol; Meperidine; Methadone; Methods; Morphine; Narcotics; Pentazocine

1970
[Permeation of active morphine-like substances at their sites of antinociceptive action in the brain as a function of their lipid-solubility following intravenous and intraventricular application].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:5

    Topics: Animals; Brain; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Dental Pulp Test; Fentanyl; Hydromorphone; Ketones; Kinetics; Levorphanol; Lipids; Methadone; Morphinans; Morphine; Piperidines; Rabbits; Solubility; Tritium

1970
Analgesic narcotic antagonists. 1. 8 beta-Alkyl-, 8 beta-acyl-, and 8 beta-(tertiary alcohol)dihydrocodeinones and -dihydromorphinones.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:2

    Topics: Acetates; Analgesics; Animals; Codeine; Hydrocodone; Hydromorphone; Male; Mice; Morphine; Narcotic Antagonists; Rats; Reaction Time; Structure-Activity Relationship

1980
Opiates and thermoregulation in mice. I. Agonists.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Animals; Benzimidazoles; Body Temperature Regulation; Codeine; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Hydromorphone; Isonipecotic Acids; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Narcotics; Oxymorphone

1980
Clinical effects of parenteral narcotics in hospitalized medical patients.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Codeine; Drug Utilization; Female; Humans; Hydromorphone; Injections; Male; Methadone; Morphine; Narcotics; Opium

1980
Zinc tannate salts of heroin, LAAM and hydromorphone attenuate opiate withdrawal syndrome.
    Psychopharmacology, 1980, Volume: 68, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Codeine; Delayed-Action Preparations; Heroin; Humans; Hydromorphone; Male; Methadone; Methadyl Acetate; Opioid-Related Disorders; Rats; Substance Withdrawal Syndrome; Zinc

1980
Radioimmunoassay of hydromorphone and hydrocodone in human plasma.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:10

    Topics: Codeine; Humans; Hydrocodone; Hydromorphone; Radioimmunoassay

1980
Hydromorphone detected in bile following hydrocodone ingestion.
    Journal of forensic sciences, 1982, Volume: 27, Issue:1

    Topics: Adult; Bile; Codeine; Humans; Hydrocodone; Hydromorphone; Male

1982
14-alkoxy dihydrocodeinones, dihydromorphinones, and morphinanones--a new class of narcotic analgesics.
    NIDA research monograph, 1982, Volume: 41

    Topics: Analgesics, Opioid; Animals; Codeine; Hydrocodone; Hydromorphone; Mice; Morphine Derivatives; Nociceptors; Rats

1982
[Synthesis of long-acting analgesic hydrazone derivatives of 14-hydroxycodeinone and 14-hydroxymorphine].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:6

    Topics: Analgesics; Animals; Codeine; Hydromorphone; Mice; Oxycodone; Oxymorphone

1983
Facilitation of thin-layer chromatographic identification of opiates by derivatization with acetic anhydride or methoxyamine.
    Journal of analytical toxicology, 1995, Volume: 19, Issue:5

    Topics: Acetic Anhydrides; Chromatography, Thin Layer; Codeine; Humans; Hydrocodone; Hydromorphone; Hydroxylamines; Indicators and Reagents; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone

1995
Biological synthesis of the analgesic hydromorphone, an intermediate in the metabolism of morphine, by Pseudomonas putida M10.
    Applied and environmental microbiology, 1993, Volume: 59, Issue:7

    Topics: Biodegradation, Environmental; Codeine; Hydrocodone; Hydromorphone; Morphine; NAD; Oxidoreductases; Pseudomonas putida

1993
14 beta-[(p-nitrocinnamoyl)amino]morphinones, 14 beta-[(p-nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: synthesis and receptor activity.
    Journal of medicinal chemistry, 1993, Oct-15, Volume: 36, Issue:21

    Topics: Animals; Brain; Cattle; Cinnamates; Codeine; Hydromorphone; Receptors, Opioid; Structure-Activity Relationship

1993
The detection of hydrocodone in meconium: two case studies.
    Journal of analytical toxicology, 1995, Volume: 19, Issue:6

    Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydrolysis; Hydromorphone; Infant, Newborn; Meconium; Morphine

1995
Engineering pathways in Escherichia coli for the synthesis of morphine alkaloid analgesics and antitussives.
    Annals of the New York Academy of Sciences, 1996, Oct-12, Volume: 799

    Topics: Alcohol Oxidoreductases; Bacterial Proteins; Biotransformation; Cloning, Molecular; Codeine; Escherichia coli; Hydrocodone; Hydromorphone; Morphine; Oxidoreductases; Plasmids; Pseudomonas putida

1996
Antinociceptive and immunosuppressive effects of opiate drugs: a structure-related activity study.
    British journal of pharmacology, 1997, Volume: 121, Issue:4

    Topics: Animals; Cell Division; Codeine; Hydromorphone; Immune System; Immunosuppression Therapy; Interleukin-2; Male; Mice; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotics; Oxycodone; Structure-Activity Relationship

1997
Biological production of semisynthetic opiates using genetically engineered bacteria.
    Bio/technology (Nature Publishing Company), 1995, Volume: 13, Issue:7

    Topics: Alcohol Oxidoreductases; Analgesics, Opioid; Bacterial Proteins; Codeine; Escherichia coli; Genetic Engineering; Hydrocodone; Hydromorphone; Morphine; Oxidoreductases; Plasmids; Recombinant Proteins

1995
Distinction among eight opiate drugs in urine by gas chromatography-mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 20, Issue:5

    Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Molecular Structure; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone

1999
[Opioids. Pharmacology, clinic, prospectives for an extensive use].
    Recenti progressi in medicina, 2000, Volume: 91, Issue:12

    Topics: Analgesics, Opioid; Codeine; Drug Tolerance; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Oxycodone; Receptors, Opioid; Tramadol

2000
The diagnosis and treatment of cough.
    The New England journal of medicine, 2001, Apr-05, Volume: 344, Issue:14

    Topics: Antitussive Agents; Codeine; Cough; Humans; Hydromorphone; Narcotics

2001
The simultaneous determination of codeine, morphine, hydrocodone, hydromorphone, 6-acetylmorphine, and oxycodone in hair and oral fluid.
    Journal of analytical toxicology, 2002, Volume: 26, Issue:3

    Topics: Codeine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Reproducibility of Results; Saliva; Substance Abuse Detection

2002
Assessment of biodegradable controlled release rod systems for pain relief applications.
    Journal of biomaterials science. Polymer edition, 2002, Volume: 13, Issue:1

    Topics: Analgesics, Opioid; Biocompatible Materials; Biodegradation, Environmental; Codeine; Drug Delivery Systems; Hydromorphone; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Morphine; Pain; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Time Factors

2002
In vivo pain relief effectiveness of an analgesic-anesthetic carrying biodegradable controlled release rod systems.
    Journal of biomaterials science. Polymer edition, 2003, Volume: 14, Issue:6

    Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Biocompatible Materials; Biodegradation, Environmental; Bupivacaine; Codeine; Drug Delivery Systems; Drug Implants; Female; Hydromorphone; Lactic Acid; Morphine; Pain; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Time Factors

2003
Effect of chlorpromazine on addiction; a preliminary report of two cases of dilaudid, morphine and codeine addictions.
    The West Virginia medical journal, 1956, Volume: 52, Issue:1

    Topics: Chlorpromazine; Codeine; Humans; Hydromorphone; Morphine; Morphine Dependence; Substance-Related Disorders

1956
[On the chromatographic evaluation of the purity of dihydromorphinone hydrochloride, dihydrocodeine bitartrate, dihydrocodeinone bitartrate and codeine phosphate. 8. Report on the behavior of alkaloid salt solutions on aluminum oxide columns].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1960, Volume: 293/65

    Topics: Alkaloids; Aluminum Oxide; Chromatography; Codeine; Hydrocodone; Hydromorphone

1960
[Experimental study of the effects of cholecystokinin on bile ducts subjected to the action of morphine-derivative substances].
    Revue internationale d'hepatologie, 1962, Volume: 12

    Topics: Bile Ducts; Cholecystokinin; Codeine; Hydromorphone; Morphine; Nalorphine

1962
[Studies on some habit-forming drugs with column chromatography].
    Arzneimittel-Forschung, 1962, Volume: 12

    Topics: Chromatography; Codeine; Habits; Humans; Hydromorphone; Morphine

1962
[Behavior modifiers inthe study of bile ducts. (Combined action of morphine substances and cholecystokinin)].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1963, Volume: 44

    Topics: Ampulla of Vater; Bile Ducts; Cholecystokinin; Codeine; Dextromoramide; Hydromorphone; Meperidine; Methadone; Morphine; Opium

1963
DEATH IN STATUS ASTHMATICUS. ROLE OF SEDATION.
    Diseases of the chest, 1963, Volume: 44

    Topics: Amobarbital; Asthma; Chloral Hydrate; Codeine; Diphenhydramine; Hydromorphone; Hypnotics and Sedatives; Meperidine; Morphine; Mortality; Phenobarbital; Status Asthmaticus; Toxicology

1963
THE EFFECT OF MORPHINE AND RELATED SUBSTANCES ON THE TOXICITY OF VENOMS. I. CENTRUROIDES SCULPTURATUS EWING SCORPION VENOM.
    The American journal of tropical medicine and hygiene, 1964, Volume: 13

    Topics: Animals; Codeine; Hydromorphone; Meperidine; Morphine; Phosphates; Rats; Research; Scorpion Venoms; Scorpions; Snake Bites; Sulfates; Toxicology; Venoms

1964
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS.
    Wisconsin medical journal, 1964, Volume: 63

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Narcotics; Oxymorphone; Pain; Phenazocine; Piperidines

1964
BARBITURATE USE IN NARCOTIC ADDICTS.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine Dependence; Narcotics; Opium; Pentobarbital; Seizures; Statistics as Topic; Substance-Related Disorders; Toxicology; Urea

1964
[PHARMACOLOGICAL STUDIES ON MORPHINE DERIVATIVES. 3. ON THE CHEMICAL STRUCTURE-ACTIVITY RELATIONSHIPS OF 14-HYDROXYMORPHINE DERIVATIVES].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1964, Volume: 84

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antitussive Agents; Codeine; Hydromorphone; Morphine; Morphine Derivatives; Nalorphine; Oxymorphone; Pharmacology; Research; Structure-Activity Relationship; Toxicology

1964
A RAPID SCREENING TEST FOR POTENTIAL ADDICTION LIABILITY OF NEW ANALGESIC AGENTS.
    Toxicology and applied pharmacology, 1964, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior, Addictive; Codeine; Dextropropoxyphene; Heroin; Hydromorphone; Meperidine; Methadone; Mice; Morphine; Phenazocine; Research; Substance-Related Disorders; Toxicology

1964
RELATIVE POTENCY OF CODEINE, METHADONE AND DIHYDROMORPHINONE TO MORPHINE IN SELF-MAINTAINED ADDICT RATS.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Jan-08, Volume: 249

    Topics: Codeine; Hydromorphone; Methadone; Morphine; Morphine Dependence; Periodicity; Pharmacology; Rats; Research

1965
Pain control via opioid analgesic-local anesthetic loaded IPNs.
    Current drug delivery, 2004, Volume: 1, Issue:1

    Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Bupivacaine; Codeine; Delayed-Action Preparations; Drug Delivery Systems; Drug Implants; Excipients; Female; Hydromorphone; Ligation; Morphine; Pain; Pain Measurement; Polyesters; Polyhydroxyethyl Methacrylate; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Neuropathy; Solubility

2004
[Determination of opiates in biological human samples by liquid chromatography-tandem mass spectrometry].
    Fa yi xue za zhi, 2006, Volume: 22, Issue:1

    Topics: Chromatography, Liquid; Codeine; Forensic Medicine; Hair; Humans; Hydrocodone; Hydromorphone; Morphine; Narcotics; Reproducibility of Results; Saliva; Substance Abuse Detection; Tandem Mass Spectrometry

2006
Multiple opioids in pain management.
    Canadian family physician Medecin de famille canadien, 2007, Volume: 53, Issue:12

    Topics: Aged, 80 and over; Analgesics, Opioid; Arthralgia; Codeine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Therapy, Combination; Fentanyl; Follow-Up Studies; Humans; Hydromorphone; Male; Osteoarthritis, Hip; Pain Measurement; Severity of Illness Index

2007
Effects of morphine, codeine, and dilaudid on blood flow.
    The Journal of pharmacology and experimental therapeutics, 1949, Volume: 95, Issue:3

    Topics: Blood Circulation; Codeine; Hemodynamics; Humans; Hydromorphone; Morphine; Morphine Derivatives

1949
The detection of hydromorphone in urine specimens with high morphine concentrations.
    Journal of forensic sciences, 2008, Volume: 53, Issue:3

    Topics: Analgesics, Opioid; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydromorphone; Morphine

2008
Palliative care intervention for choice and use of opioids in the last hours of life.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2008, Volume: 63, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Female; Humans; Hydromorphone; Male; Meperidine; Middle Aged; Oxycodone; Palliative Care; Terminal Care

2008
Prevalence of dihydrocodeine in hydrocodone positive postmortem specimens.
    Journal of forensic and legal medicine, 2009, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Male; Middle Aged; Postmortem Changes; Prevalence; Substance Abuse Detection; Young Adult

2009
Quantitation of opioids in blood and urine using gas chromatography-mass spectrometry (GC-MS).
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 603

    Topics: Analgesics, Opioid; Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Reproducibility of Results; Solid Phase Extraction

2010
Quantitation of morphine, codeine, hydrocodone, hydromorphone, oxycodone, oxymorphone, and 6-monoacetylmorphine (6-MAM) in urine, blood, serum, or plasma using liquid chromatography with tandem mass spectrometry detection.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 603

    Topics: Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry

2010
Evaluation of the usefulness of an oxycodone immunoassay in combination with a traditional opiate immunoassay for the screening of opiates in urine.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:2

    Topics: Acetylation; Codeine; False Negative Reactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Hydrocodone; Hydromorphone; Immunoassay; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection

2010
Studies on analgesics; the time-action curves of morphine, codeine, dilaudid and demerol by various methods of administration; analgesic activity of acetylsalicylic acid and aminopyrine.
    The Journal of pharmacology and experimental therapeutics, 1945, Volume: 84

    Topics: Aminopyrine; Analgesics; Anesthesia; Aspirin; Codeine; Hydromorphone; Meperidine; Morphine; Salicylates

1945
Quantitation of opioids in whole blood by electron impact-gas chromatography-mass spectrometry.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:2

    Topics: Analgesics, Opioid; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection

2011
Canadian guideline for safe and effective use of opioids for chronic noncancer pain: clinical summary for family physicians. Part 1: general population.
    Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:11

    Topics: Analgesics, Opioid; Benzodiazepines; Canada; Chronic Pain; Codeine; Humans; Hydromorphone; Mass Screening; Opioid-Related Disorders; Oxycodone; Patient Education as Topic; Sleep Apnea Syndromes; Tramadol

2011
Pharmacists' experiences with dispensing opioids: provincial survey.
    Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:11

    Topics: Adult; Aged; Alcohol Drinking; Analgesics, Opioid; Chronic Pain; Codeine; Data Collection; Drug Prescriptions; Drug-Seeking Behavior; Female; Health Knowledge, Attitudes, Practice; Humans; Hydromorphone; Hypnotics and Sedatives; Interdisciplinary Communication; Interprofessional Relations; Male; Medication Adherence; Middle Aged; Ontario; Oxycodone; Pharmacists; Practice Patterns, Physicians'

2011
Hydrophilic interaction LC-MS/MS analysis of opioids in urine: significance of glucuronide metabolites.
    Bioanalysis, 2011, Volume: 3, Issue:23

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Gas Chromatography-Mass Spectrometry; Glucuronides; Humans; Hydrocodone; Hydromorphone; Hydrophobic and Hydrophilic Interactions; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry

2011
Observations on the urine metabolic profile of codeine in pain patients.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:2

    Topics: Analgesics, Opioid; Biotransformation; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Drug Monitoring; Enzyme Inhibitors; Humans; Hydrocodone; Hydromorphone; Pain; Retrospective Studies; Risk Assessment; Risk Factors; Urinalysis

2014
A microbial biomanufacturing platform for natural and semisynthetic opioids.
    Nature chemical biology, 2014, Volume: 10, Issue:10

    Topics: Bacterial Proteins; Codeine; Gene Dosage; Gene Expression; Hydrocodone; Hydromorphone; Metabolic Engineering; Metabolic Networks and Pathways; Morphine; Oxycodone; Papaver; Plant Proteins; Pseudomonas putida; Saccharomyces cerevisiae; Thebaine

2014
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Separation of opiate isomers using electrospray ionization and paper spray coupled to high-field asymmetric waveform ion mobility spectrometry.
    Journal of the American Society for Mass Spectrometry, 2015, Volume: 26, Issue:5

    Topics: Aerosols; Analgesics, Opioid; Chemistry, Clinical; Codeine; Electrochemical Techniques; Feasibility Studies; Forensic Toxicology; Hydromorphone; Morphine; Paper; Solvents; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry

2015
LC-MS-MS Method for Analysis of Opiates in Wastewater During Football Games II.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:5

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Football; Humans; Hydrocodone; Hydromorphone; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical

2016
Degradation of Opioids and Opiates During Acid Hydrolysis Leads to Reduced Recovery Compared to Enzymatic Hydrolysis.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:8

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Glucuronidase; Humans; Hydrocodone; Hydrolysis; Hydromorphone; Morphine; Morphine Derivatives; Opiate Alkaloids; Oxycodone; Oxymorphone; Specimen Handling; Tandem Mass Spectrometry

2016
Changes in Provider Prescribing Patterns After Implementation of an Emergency Department Prescription Opioid Policy.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Drug Prescriptions; Emergency Service, Hospital; Female; Humans; Hydrocodone; Hydromorphone; Male; Middle Aged; Organizational Policy; Practice Patterns, Physicians'; Quality Improvement; United States

2017
The Effect of Opioid Prescribing Guidelines on Prescriptions by Emergency Physicians in Ohio.
    Annals of emergency medicine, 2017, Volume: 70, Issue:6

    Topics: Adult; Analgesics, Opioid; Codeine; Emergency Service, Hospital; Female; Guideline Adherence; Humans; Hydrocodone; Hydromorphone; Male; Middle Aged; Ohio; Oxycodone; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tramadol

2017
Interpretation of Urine Drug Screens: Metabolites and Impurities.
    JAMA, 2017, Nov-07, Volume: 318, Issue:17

    Topics: Analgesics, Opioid; Codeine; False Positive Reactions; Female; Humans; Hydromorphone; Immunoassay; Mass Spectrometry; Methadone; Middle Aged; Morphine; Substance Abuse Detection

2017
Detection and quantification of codeine-6-glucuronide, hydromorphone-3-glucuronide, oxymorphone-3-glucuronide, morphine 3-glucuronide and morphine-6-glucuronide in human hair from opioid users by LC-MS-MS.
    Journal of analytical toxicology, 2018, Mar-01, Volume: 42, Issue:2

    Topics: Chromatography, Liquid; Codeine; Glucuronates; Hair; Humans; Hydromorphone; Limit of Detection; Morphine Derivatives; Opioid-Related Disorders; Reproducibility of Results; Specimen Handling; Substance Abuse Detection; Tandem Mass Spectrometry

2018
Development of a Quantitative LC-MS-MS Assay for Codeine, Morphine, 6-Acetylmorphine, Hydrocodone, Hydromorphone, Oxycodone and Oxymorphone in Neat Oral Fluid.
    Journal of analytical toxicology, 2018, Jul-01, Volume: 42, Issue:6

    Topics: Analgesics, Opioid; Calibration; Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Opioid-Related Disorders; Oxycodone; Oxymorphone; Predictive Value of Tests; Reference Standards; Reproducibility of Results; Saliva; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry

2018
Which opioids in case of mast cell activation disorders?
    The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:4

    Topics: Analgesics, Opioid; Codeine; Databases, Factual; Histamine Release; Humans; Hydromorphone; Mast Cells; Mastocytosis; Pharmacovigilance; Tramadol

2019
At-a-glance - The role of opioid toxicity in suicide deaths in Alberta, 2000 to 2016.
    Health promotion and chronic disease prevention in Canada : research, policy and practice, 2018, Volume: 38, Issue:9

    Topics: Adult; Age Factors; Alberta; Analgesics, Opioid; Codeine; Female; Humans; Hydromorphone; International Classification of Diseases; Male; Middle Aged; Morphine; Oxycodone; Sex Factors; Suicide; Vital Statistics

2018
Identification of opioids in surface and wastewaters by LC/QTOF-MS using retrospective data analysis.
    The Science of the total environment, 2019, May-10, Volume: 664

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Data Analysis; Environmental Monitoring; Fentanyl; Heroin; Hydrocodone; Hydromorphone; Minnesota; Morphine; Morphine Derivatives; Oxycodone; Retrospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater; Water Pollutants, Chemical

2019
Opioid prescribing practices in a pediatric burn tertiary care facility: Is it time to change?
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:1

    Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Burn Units; Burns; Child; Child, Preschool; Codeine; Drug Combinations; Female; Fentanyl; Hospitalization; Humans; Hydrocodone; Hydromorphone; Infant; Length of Stay; Male; Morphine; Pain Management; Patient Discharge; Practice Patterns, Physicians'; Retrospective Studies; Tertiary Care Centers; Tramadol

2020
Comparative Analysis of ELISA Immunoassay and LC-QTOF for Opiate Screening.
    Journal of analytical toxicology, 2020, May-18, Volume: 44, Issue:4

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Enzyme-Linked Immunosorbent Assay; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection

2020
Trends in Postpartum Opioid Prescribing: A Time Series Analysis.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:4

    Topics: Adult; Analgesics, Opioid; Breast Feeding; Codeine; Female; Humans; Hydromorphone; Infant, Newborn; Interrupted Time Series Analysis; Lactation; Morphine; Ontario; Oxycodone; Postpartum Period; Practice Patterns, Physicians'; Pregnancy; Young Adult

2021
Hydromorphone and codeine concentrations in oral fluid specimens from patients receiving substitution therapy with Substitol™ (morphine sulfate).
    Drug testing and analysis, 2021, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Buprenorphine; Codeine; Female; Humans; Hydromorphone; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Saliva; Substance Abuse Detection

2021
Declines and regional variation in opioid distribution by U.S. hospitals.
    Pain, 2022, 06-01, Volume: 163, Issue:6

    Topics: Analgesics, Opioid; Buprenorphine; Codeine; Hospitals; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Oxymorphone; United States

2022
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases.
    Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8

    Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem

2022
Opioid dispensing after Cesarean delivery in British Columbia: a historical cohort analysis from 2004 to 2019.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022, Volume: 69, Issue:8

    Topics: Aftercare; Analgesics, Opioid; British Columbia; Codeine; Cohort Studies; Humans; Hydromorphone; Patient Discharge; Practice Patterns, Physicians'; Tramadol

2022
Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns.
    JAMA network open, 2022, 08-01, Volume: 5, Issue:8

    Topics: Adult; Analgesics, Opioid; Codeine; Cohort Studies; Female; Humans; Hydrocodone; Hydromorphone; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine; Neonatal Abstinence Syndrome; Oxycodone; Pain; Pregnancy; Prescriptions; Substance Withdrawal Syndrome; Tramadol; United States

2022
Safety of prenatal opioid analgesics: Do results differ between public health insurance beneficiary and population-based cohorts?
    Birth defects research, 2023, 03-15, Volume: 115, Issue:5

    Topics: Analgesics, Opioid; Codeine; Female; Humans; Hydromorphone; Insurance Benefits; Oxycodone; Pregnancy; Public Health

2023