hydromorphone and clonidine

hydromorphone has been researched along with clonidine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's0 (0.00)18.2507
2000's13 (56.52)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bigelow, GE; Liebson, IA; Preston, KL1
Jasinski, DR; Johnson, RE; Kocher, TR1
Coombs, DW; Fratkin, JD; Jensen, LE; Murphy, CA; Saunders, RL1
Cousins, MJ; Tanelian, DL1
Frye, CB; Vance, MA1
Macres, S; Richeimer, S1
Ackerman, LL; Follett, KA; Rosenquist, RW1
Favre, J; Galarza, M; Janszen, M; Taha, A; Taha, J1
Buster, P; Coyne, PJ; Hansen, LA; Laird, J; Smith, TJ1
Dunn, E; McCartney, C; Peng, P; Rudich, Z1
Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F1
Carvallo, D; Johnson, JL; Mazurek, MS; Presson, RG; Vetter, TR1
Bianchi, F; Ginggen, A; Tardy, Y1
Chiravuri, S; Couch, JP; Liu, H; Ruan, X; Wang, F1
Bae, JJ; Bieltz, M; Liu, SS; Ma, Y; Wukovits, B1
Ewan, EE; Martin, TJ1
Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE1
Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S1

Reviews

2 review(s) available for hydromorphone and clonidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Analgesia in the surgical intensive care unit.
    Postgraduate medical journal, 2017, Volume: 93, Issue:1095

    Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities

2017

Trials

4 trial(s) available for hydromorphone and clonidine

ArticleYear
Clonidine in morphine withdrawal. Differential effects on signs and symptoms.
    Archives of general psychiatry, 1985, Volume: 42, Issue:11

    Topics: Clonidine; Dose-Response Relationship, Drug; Heroin Dependence; Hospitalization; Humans; Hydromorphone; Male; Morphine; Opioid-Related Disorders; Placebos; Research Design; Substance Withdrawal Syndrome

1985
Long-term outcomes during treatment of chronic pain with intrathecal clonidine or clonidine/opioid combinations.
    Journal of pain and symptom management, 2003, Volume: 26, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Chronic Disease; Clonidine; Drug Therapy, Combination; Female; Humans; Hydromorphone; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged; Pain; Treatment Outcome

2003
Stability of clonidine in clonidine-hydromorphone mixture from implanted intrathecal infusion pumps in chronic pain patients.
    Journal of pain and symptom management, 2004, Volume: 28, Issue:6

    Topics: Analgesics; Chronic Disease; Clonidine; Complex Mixtures; Drug Combinations; Drug Stability; Drug Storage; Humans; Hydromorphone; Infusion Pumps, Implantable; Injections, Spinal; Pain; Quality Assurance, Health Care

2004
A comparison of single-dose caudal clonidine, morphine, or hydromorphone combined with ropivacaine in pediatric patients undergoing ureteral reimplantation.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:6

    Topics: Amides; Analgesia, Epidural; Child; Child, Preschool; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydromorphone; Infant; Injections, Spinal; Male; Morphine; Pain, Postoperative; Replantation; Ropivacaine; Ureter

2007

Other Studies

17 other study(ies) available for hydromorphone and clonidine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Self-administration of clonidine, oxazepam, and hydromorphone by patients undergoing methadone detoxification.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:2

    Topics: Adult; Clonidine; Drug Administration Schedule; Humans; Hydromorphone; Male; Methadone; Opioid-Related Disorders; Oxazepam; Psychomotor Performance; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders; Surveys and Questionnaires

1985
Continuous intrathecal hydromorphone and clonidine for intractable cancer pain.
    Journal of neurosurgery, 1986, Volume: 64, Issue:6

    Topics: Carcinoma; Clonidine; Female; Humans; Hydromorphone; Injections, Spinal; Middle Aged; Pain, Intractable; Uterine Cervical Neoplasms

1986
Failure of epidural opioid to control cancer pain in a patient previously treated with massive doses of intravenous opioid.
    Pain, 1989, Volume: 36, Issue:3

    Topics: Adenocarcinoma; Bupivacaine; Cecal Neoplasms; Clonidine; Female; Humans; Hydromorphone; Infusions, Intravenous; Injections, Epidural; Lidocaine; Middle Aged; Pain; Substance Withdrawal Syndrome

1989
Hypertensive crisis and myocardial infarction following massive clonidine overdose.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:5

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Breast Neoplasms; Clonidine; Drug Overdose; Drug Therapy, Combination; Female; Humans; Hydromorphone; Hypertensive Encephalopathy; Infusion Pumps, Implantable; Middle Aged; Myocardial Infarction; Spinal Neoplasms

2000
Successful treatment of erythromelalgia with intrathecal hydromorphone and clonidine.
    The Clinical journal of pain, 2000, Volume: 16, Issue:4

    Topics: Adrenergic alpha-Agonists; Age of Onset; Aged; Aged, 80 and over; Analgesics, Opioid; Clonidine; Erythromelalgia; Female; Humans; Hydromorphone; Infusion Pumps, Implantable; Injections, Spinal

2000
Correlation between withdrawal symptoms and medication pump residual volume in patients with implantable SynchroMed pumps.
    Neurosurgery, 2004, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Opioid; Baclofen; Bupivacaine; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Equipment Design; Equipment Failure; Female; Fentanyl; Humans; Hydromorphone; Infusion Pumps, Implantable; Male; Middle Aged; Morphine; Muscle Spasticity; Neurologic Examination; Pain, Intractable; Quality of Life; Retrospective Studies; Substance Withdrawal Syndrome

2004
Massive hydromorphone dose delivered subcutaneously instead of intrathecally: guidelines for prevention and management of opioid, local anesthetic, and clonidine overdose.
    Journal of pain and symptom management, 2004, Volume: 28, Issue:3

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Clonidine; Drug Overdose; Female; Humans; Hydromorphone; Infusion Pumps, Implantable; Infusions, Parenteral

2004
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics.
    Anesthesiology, 2007, Volume: 106, Issue:2

    Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroin; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Male; Methadone; Morphine; Neuralgia; Pain; Rats; Rats, Inbred F344; Self Administration

2007
Stability and compatibility of drug mixtures in an implantable infusion system.
    Anaesthesia, 2008, Volume: 63, Issue:9

    Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Clonidine; Drug Combinations; Drug Interactions; Drug Stability; Humans; Hydromorphone; Infusion Pumps, Implantable; Injections, Spinal; Morphine

2008
Recurrent cellulitis associated with long-term intrathecal opioid infusion therapy: a case report and review of the literature.
    Pain medicine (Malden, Mass.), 2010, Volume: 11, Issue:6

    Topics: Analgesics, Opioid; Baclofen; Cellulitis; Clonidine; Edema; Female; GABA Agonists; Humans; Hydromorphone; Injections, Spinal; Low Back Pain; Middle Aged; Recurrence; Treatment Outcome

2010
A prospective survey of patient-controlled epidural analgesia with bupivacaine and clonidine after total hip replacement: a pre- and postchange comparison with bupivacaine and hydromorphone in 1,000 patients.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:5

    Topics: Adrenergic alpha-Agonists; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacaine; Clonidine; Drug Therapy, Combination; Female; Humans; Hydromorphone; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies

2011
Rewarding electrical brain stimulation in rats after peripheral nerve injury: decreased facilitation by commonly abused prescription opioids.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Adenosine; Amines; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hydromorphone; Injections, Spinal; Male; Methadone; Oxycodone; Peripheral Nerve Injuries; Rats; Rats, Inbred F344; Reward

2011
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
    Journal of analytical toxicology, 2016, Volume: 40, Issue:8

    Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine

2016