Compounds > hydrogen

hydrogen and methotrexate

hydrogen has been researched along with methotrexate in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delcamp, TJ; DeYarman, MT; Freisheim, JH; Nirmala, NR; Stockman, BJ; Wagner, G1
Benkovic, SJ; Falzone, CJ; Wright, PE1
Birdsall, B; Cheung, HT; Feeney, J; Hammond, SJ; Roberts, GC; Searle, MS1
Neal, GE; Stanley, BG; Williams, DC1
Bauer, CJ; Birdsall, B; Carr, MD; Feeney, J; Frenkiel, TA; McCormick, JE; Sali, D; Soteriou, A1
Bennett, BC; Dealwis, CG; Howell, EE; Meilleur, F; Myles, DA1
Nicholls, A; Sayle, R1

Other Studies

7 other study(ies) available for hydrogen and methotrexate

ArticleYear
Sequence-specific 1H and 15N resonance assignments for human dihydrofolate reductase in solution.
    Biochemistry, 1992, Jan-14, Volume: 31, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Folic Acid; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Methotrexate; Molecular Sequence Data; Mutation; Nitrogen Isotopes; Protein Conformation; Solutions; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

1992
Evidence for two interconverting protein isomers in the methotrexate complex of dihydrofolate reductase from Escherichia coli.
    Biochemistry, 1991, Feb-26, Volume: 30, Issue:8

    Topics: Escherichia coli; Hydrogen; Isomerism; Magnetic Resonance Spectroscopy; Methotrexate; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase; X-Ray Diffraction

1991
Structural comparisons of complexes of methotrexate analogues with Lactobacillus casei dihydrofolate reductase by two-dimensional 1H NMR at 500 MHz.
    Biochemistry, 1987, Dec-29, Volume: 26, Issue:26

    Topics: Folic Acid Antagonists; Hydrogen; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase

1987
The presence of a substance with hydrogen transporting properties in some samples of methotrexate.
    Biochemical pharmacology, 1968, Volume: 17, Issue:10

    Topics: Benzoates; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Drug Contamination; Drug Storage; Freeze Drying; Hydrogen; Methotrexate; Mitosis; NAD; NADP; Oxidation-Reduction; Tetrazolium Salts

1968
3D 13C/1H NMR-based assignments for side-chain resonances of Lactobacillus casei dihydrofolate reductase. Evidence for similarities between the solution and crystal structures of the enzyme.
    Journal of biomolecular NMR, 1993, Volume: 3, Issue:5

    Topics: Amino Acid Sequence; Binding Sites; Carbon Isotopes; Crystallization; Hydrogen; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Molecular Sequence Data; Protein Structure, Tertiary; Solutions; Tetrahydrofolate Dehydrogenase

1993
Preliminary neutron diffraction studies of Escherichia coli dihydrofolate reductase bound to the anticancer drug methotrexate.
    Acta crystallographica. Section D, Biological crystallography, 2005, Volume: 61, Issue:Pt 5

    Topics: Antimetabolites, Antineoplastic; Crystallization; Deuterium Oxide; Escherichia coli; Folic Acid Antagonists; Hydrogen; Methotrexate; Neutron Diffraction; Plasmids; Protein Binding; Tetrahydrofolate Dehydrogenase

2005
Electrostatic evaluation of isosteric analogues.
    Journal of computer-aided molecular design, 2006, Volume: 20, Issue:4

    Topics: Binding Sites; Carrier Proteins; Computer Simulation; Cyclooxygenase 2; Drug Design; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; Hydrogen; In Vitro Techniques; Ligands; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Methotrexate; Models, Molecular; Neuraminidase; Protein Binding; Static Electricity; Tetrahydrofolate Dehydrogenase; Thermodynamics

2006