hydrogen and cobamamide

hydrogen has been researched along with cobamamide in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's3 (15.79)18.2507
2000's13 (68.42)29.6817
2010's1 (5.26)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Abend, A; Kunz, M; Rétey, J; Such, P; Zhao, Y1
Frey, PA1
Bothe, H; Buckel, W; Hoffmann, B; Konrat, R; Kräutler, B1
Masuda, J; Morimoto, Y; Shibata, N; Toraya, T; Yasuoka, N1
Bandarian, V; Reed, GH1
Chang, CH; Frey, PA; Tang, KH1
Utada, AS; Warncke, K1
Doll, KM; Finke, RG1
Bender, BR; Doll, KM; Finke, RG1
DOLPHIN, D; JOHNSON, AW; RODRIGO, R1
Ball, P1
Reed, GH1
Kamachi, T; Toraya, T; Yoshizawa, K2
Cheng, MC; Marsh, EN1
Canfield, JM; Warncke, K1
Banerjee, R; Dybala-Defratyka, A; Paneth, P; Truhlar, DG1
Håkansson, K; Marsh, EN; Song, H; Yoon, M1
Marsh, ENG1

Reviews

3 review(s) available for hydrogen and cobamamide

ArticleYear
Lysine 2,3-aminomutase: is adenosylmethionine a poor man's adenosylcobalamin?
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1993, Volume: 7, Issue:8

    Topics: Amino Acid Isomerases; Cobamides; Escherichia coli; Hydrogen; Intramolecular Transferases; Lactobacillus; Molecular Structure; S-Adenosylmethionine

1993
SOME REACTIONS OF THE VITAMIN B 12 COENZYME AND ITS ALKYL ANALOGUES.
    Annals of the New York Academy of Sciences, 1964, Apr-24, Volume: 112

    Topics: Acids; Amides; Chemical Phenomena; Chemistry; Chlorine; Cobamides; Coenzymes; Cyanides; Hydrogen; Light; Organic Chemicals; Research; Vitamin B 12

1964
Radical mechanisms in adenosylcobalamin-dependent enzymes.
    Current opinion in chemical biology, 2004, Volume: 8, Issue:5

    Topics: Binding Sites; Carbon; Cobalt; Cobamides; Free Radicals; Glutamic Acid; Glutarates; Hydrogen; Isotope Labeling; Kinetics; Models, Molecular; Ribonucleotide Reductases

2004

Other Studies

16 other study(ies) available for hydrogen and cobamamide

ArticleYear
Electron paramagnetic resonance studies of the methylmalonyl-CoA mutase reaction. Evidence for radical intermediates using natural and artificial substrates as well as the competitive inhibitor 3-carboxypropyl-CoA.
    European journal of biochemistry, 1994, Nov-01, Volume: 225, Issue:3

    Topics: Binding, Competitive; Carbon; Cobalt; Cobamides; Coenzyme A; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen; Kinetics; Methylmalonyl-CoA Mutase; Propionibacterium; Substrate Specificity

1994
Structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium cochlearium.
    European journal of biochemistry, 1999, Volume: 263, Issue:1

    Topics: Amino Acid Sequence; Catalytic Domain; Clostridium; Cobamides; Hydrogen; Intramolecular Transferases; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Thermodynamics

1999
How a protein generates a catalytic radical from coenzyme B(12): X-ray structure of a diol-dehydratase-adeninylpentylcobalamin complex.
    Structure (London, England : 1993), 2000, Jul-15, Volume: 8, Issue:7

    Topics: Bacterial Proteins; Binding Sites; Cobamides; Crystallography, X-Ray; Escherichia coli; Free Radicals; Hydrogen; Klebsiella; Ligands; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Molecular Structure; Organometallic Compounds; Photochemistry; Propanediol Dehydratase; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Vitamin B 12

2000
Isotope effects in the transient phases of the reaction catalyzed by ethanolamine ammonia-lyase: determination of the number of exchangeable hydrogens in the enzyme-cofactor complex.
    Biochemistry, 2000, Oct-03, Volume: 39, Issue:39

    Topics: Catalysis; Cobamides; Coenzymes; Deuterium; Electron Transport; Ethanolamine Ammonia-Lyase; Hydrogen; Kinetics; Models, Chemical; Spectrophotometry; Substrate Specificity; Tritium

2000
Electron transfer in the substrate-dependent suicide inactivation of lysine 5,6-aminomutase.
    Biochemistry, 2001, May-01, Volume: 40, Issue:17

    Topics: Aziridines; Catalysis; Clostridium; Cobamides; Deoxyadenosines; Electron Transport; Enzyme Activation; Free Radicals; Hydrogen; Intramolecular Transferases; Isomerism; Lysine; Solvents; Substrate Specificity; Vitamin B 12

2001
Interaction of the substrate radical and the 5'-deoxyadenosine-5'-methyl group in vitamin B(12) coenzyme-dependent ethanolamine deaminase.
    Journal of the American Chemical Society, 2001, Sep-05, Volume: 123, Issue:35

    Topics: Binding Sites; Cobamides; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Ethanolamine Ammonia-Lyase; Free Radicals; Hydrogen; Models, Chemical; Salmonella typhimurium

2001
A compelling experimental test of the hypothesis that enzymes have evolved to enhance quantum mechanical tunneling in hydrogen transfer reactions: the beta-neopentylcobalamin system combined with prior adocobalamin data.
    Inorganic chemistry, 2003, Aug-11, Volume: 42, Issue:16

    Topics: Algorithms; Biological Evolution; Cobamides; Enzymes; Hydrogen; Indicators and Reagents; Quantum Theory; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Vitamin B 12

2003
The first experimental test of the hypothesis that enzymes have evolved to enhance hydrogen tunneling.
    Journal of the American Chemical Society, 2003, Sep-10, Volume: 125, Issue:36

    Topics: Cobamides; Free Radicals; Hydrogen; Kinetics; Propanediol Dehydratase; Thermodynamics

2003
Enzymes: by chance, or by design?
    Nature, 2004, Sep-23, Volume: 431, Issue:7007

    Topics: Alcohol Dehydrogenase; Catalysis; Cobamides; Drug Design; Enzymes; Evolution, Molecular; Geobacillus stearothermophilus; Hydrogen; Kinetics; Methylmalonyl-CoA Mutase; Probability; Quantum Theory; Temperature; Vibration

2004
Catalytic roles of active-site amino acid residues of coenzyme B12-dependent diol dehydratase: protonation state of histidine and pull effect of glutamate.
    Journal of the American Chemical Society, 2004, Dec-15, Volume: 126, Issue:49

    Topics: Binding Sites; Catalysis; Cobamides; Glutamic Acid; Histidine; Hydrogen; Kinetics; Models, Molecular; Potassium; Propanediol Dehydratase; Protein Conformation; Quantum Theory; Thermodynamics

2004
Isotope effects for deuterium transfer between substrate and coenzyme in adenosylcobalamin-dependent glutamate mutase.
    Biochemistry, 2005, Feb-22, Volume: 44, Issue:7

    Topics: Catalysis; Chromatography, High Pressure Liquid; Cobamides; Deoxyadenosines; Deuterium; Deuterium Exchange Measurement; Energy Transfer; Escherichia coli Proteins; Free Radicals; Glutamic Acid; Holoenzymes; Hydrogen; Intramolecular Transferases; Kinetics; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity

2005
Active site reactant center geometry in the Co(II)-product radical pair state of coenzyme B12-dependent ethanolamine deaminase determined by using orientation-selection electron spin-echo envelope modulation spectroscopy.
    The journal of physical chemistry. B, 2005, Feb-24, Volume: 109, Issue:7

    Topics: Binding Sites; Biophysics; Chemistry, Physical; Cobalt; Cobamides; Electromagnetic Fields; Electron Spin Resonance Spectroscopy; Electrons; Escherichia coli; Ethanolamine Ammonia-Lyase; Hydrogen; Models, Chemical; Molecular Conformation; Salmonella typhimurium; Spectrum Analysis

2005
Coupling of hydrogenic tunneling to active-site motion in the hydrogen radical transfer catalyzed by a coenzyme B12-dependent mutase.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jun-26, Volume: 104, Issue:26

    Topics: Binding Sites; Catalysis; Cobamides; Deuterium; Free Radicals; Hydrogen; Intramolecular Transferases; Kinetics; Models, Chemical; Models, Molecular; Motion; Quantum Theory; Vitamin B 12

2007
Computational mutation analysis of hydrogen abstraction and radical rearrangement steps in the catalysis of coenzyme B12-dependent diol dehydratase.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2007, Volume: 13, Issue:28

    Topics: Binding Sites; Catalysis; Cobamides; Computational Biology; DNA Mutational Analysis; Enzyme Activation; Hydrogen; Mutation; Propanediol Dehydratase; Propylene Glycol; Propylene Glycols; Protein Conformation; Vitamin B 12

2007
Hydrogen tunneling in adenosylcobalamin-dependent glutamate mutase: evidence from intrinsic kinetic isotope effects measured by intramolecular competition.
    Biochemistry, 2010, Apr-13, Volume: 49, Issue:14

    Topics: Aspartic Acid; Cobamides; Deoxyadenosines; Deuterium; Hydrogen; Intramolecular Transferases; Kinetics; Models, Molecular; Temperature; Thermodynamics

2010
Using kinetic isotope effects to probe the mechanism of adenosylcobalamin-dependent enzymes.
    Methods in enzymology, 2022, Volume: 669

    Topics: Cobamides; Hydrogen; Isotopes; Kinetics

2022