hydrogen has been researched along with aspartic acid in 169 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (18.93) | 18.7374 |
| 1990's | 73 (43.20) | 18.2507 |
| 2000's | 48 (28.40) | 29.6817 |
| 2010's | 15 (8.88) | 24.3611 |
| 2020's | 1 (0.59) | 2.80 |
| Authors | Studies |
|---|---|
| Cronholm, T | 1 |
| Laanbroek, HJ; Stal, LH; Veldkamp, H | 1 |
| Dressel, LA; Ivan Legg, J; McClarin, JA | 1 |
| Bogdan, AR; Gusnard, DA; Leigh, JS; Ohene-Frempong, K; Wang, Z; Zimmerman, RA | 1 |
| Li, ZW; Taube, H | 1 |
| Berry, MN; Gregory, RB; Phillips, JW | 1 |
| Barrere, B; Beloeil, JC; Berenger, G; Fedeli, O; Gillet, B; Peres, M; Seylaz, J | 1 |
| Krane, J; Petersen, SB; Schousboe, A; Sonnewald, U; Westergaard, N | 1 |
| Calabrese, G; Deicken, R; Fein, G; Fisher, SN; Hetherington, HP; Sappey-Marinier, D; Van Dyke, C; Weiner, MW | 1 |
| Botting, NP; Gani, D | 1 |
| den Hollander, JA; Luyten, PR; Nauta, JJ; Valk, J; van der Grond, J; van der Knaap, MS | 1 |
| Hida, K | 1 |
| Denger, K; Schink, B | 1 |
| Behar, KL; Ogino, T | 1 |
| Hida, K; Kwee, IL; Nakada, T | 1 |
| Garwood, M; Hendrich, K; Merkle, H; Ross, BD; Staewen, RS | 1 |
| Arakawa, T; Prestrelski, SJ | 1 |
| Bore, P; Brereton, IM; Doddrell, DM; Galloway, GJ; Haseler, LJ; Moxon, LN; Rose, SE | 1 |
| Austin, SJ; Benton, JS; Brett, EM; Connelly, A; Gadian, DG | 1 |
| Abe, H; Hida, K; Houkin, K; Iwasaki, Y; Kamiyama, H; Kashiwaba, T; Koiwa, M; Matsuzawa, H; Miyasaka, K | 1 |
| Bovée, WM; de Graaf, AA | 1 |
| Fink, K; Göthert, M; Schlicker, E | 1 |
| Balschmidt, P; Hansen, FB; Jørgensen, AM; Kristensen, SM; Led, JJ | 1 |
| Bigler, P; Burri, R; Colombo, JP; Herschkowitz, N; Posse, S; Straehl, P | 1 |
| Birken, DL; Oldendorf, WH | 1 |
| Béloeil, JC; Champagnat, J; Fortin, G; Gillet, B; Jacquin, T; Pasquier, C | 1 |
| Allen, K; Crockard, HA; Frackowiak, RS; Gadian, DG; Proctor, E; Russell, RW; Williams, SR | 1 |
| Khetwal, KS; Pathak, HD | 1 |
| Blattmann, P; Rétey, J | 1 |
| Becker, RS; Hong, JH; Hong, K | 1 |
| Robillard, G; Shulman, RG | 1 |
| Joubert, SM; Shanley, BC | 1 |
| Amidon, GL | 1 |
| Takahashi, M; Westhead, EW | 1 |
| Barker, HA; Eagar, RG; Herbst, MM; Richards, JH | 1 |
| Baltimore, BG; Barker, HA; Switzer, RL | 1 |
| Kobayashi, Y; Makino, K | 1 |
| Lwin, S | 1 |
| Backen, K; Eddy, AA; Indge, KJ; Nowacki, JA | 1 |
| Houston, M; Viswanatha, T | 1 |
| Arnone, A; Bier, CJ; Cotton, FA; Day, VW; Hazen, EE; Richardson, DC; Richardson, JS; Yonath, A | 1 |
| Craig, LC; Galardy, RE; Printz, MP | 1 |
| Klingenberg, M; von Haefen, H; Wenske, G | 1 |
| Andrako, J; Brown, ES; Smith, HL; Smith, JD | 1 |
| Blake, MI; Fang, SM; Rhodes, HJ | 1 |
| Hensgens, LA; Meijer, AJ; Nieuwenhuis, BJ; van der Meer, R | 1 |
| Burlina, AP; Hagberg, G; Mader, I; Radue, EW; Roser, W; Seelig, J | 1 |
| Lee, HK; Nalcioglu, O; Yaman, A | 1 |
| Constans, JM; Fein, G; Gerson, J; MacKay, S; Meyerhoff, DJ; Norman, D; Weiner, MW | 1 |
| Aronow, H; Beck, CK; Buchthal, S; Chang, L; Chiang, F; Cornford, M; Ernst, T; McBride, D; Miller, BL; Oropilla, G | 1 |
| Balaban, RS; Cuenod, CA; Le Bihan, D; Posse, S; Risinger, R | 1 |
| Grierson, JR; Heide, AC; Jiménez, JV; Richards, TL; Shankland, EG | 1 |
| Auriola, SO; Kauppinen, RA; Pirttilä, TR | 1 |
| Nasrallah, HA; Robitaille, PM; Schmalbrock, P; Skinner, TE | 1 |
| Oudkerk, M; Sijens, PE; van Dijk, P | 1 |
| Cerdán, S; Erhard, P; Moldes, M; Seelig, J | 1 |
| Maudsley, AA | 1 |
| Ernst, T; Hennig, J | 1 |
| Petroff, OA; Pleban, L; Prichard, JW | 1 |
| Behar, KL; Boehm, D | 1 |
| Glickson, JD; Shungu, DC | 1 |
| Cohen, JA; Dousset, V; Gonzalez-Scarano, F; Grossman, RI; Hiehle, JF; Lenkinski, RE; Ramer, KN; Schnall, MD | 1 |
| Maudsley, AA; Meyerhoff, DJ; Weiner, MW; Wu, Z | 1 |
| Hugg, JW; Matson, GB; Maudsley, AA; Weiner, MW | 1 |
| Ball, WS; Dunn, RS; Kirks, DR; Nelson, SJ; Tzika, AA; Vigneron, DB | 1 |
| Gadian, DG; Moonen, CT; Shaw, D; van Zijl, P | 1 |
| Gadian, DG; Noble, M; Urenjak, J; Williams, SR | 1 |
| Assadi-Porter, FM; Fillingame, RH | 1 |
| Crozier, S; Doddrell, DM; Glen, S; Hockings, PD; Hunter, AJ; Middleton, DA; Reid, DG; Roffman, W; Rose, SE; Rothaul, AL | 1 |
| Martin, SA; Park, CM | 1 |
| Cannon, J; Marshall, I; Sellar, RJ; Slattery, J; Wardlaw, J | 1 |
| Ransom, BR; Rose, CR | 1 |
| Adams, D; Hetherington, HP; Mason, GF; Pan, JW; Pohost, GM; Twieg, DB; Vaughn, MJ | 1 |
| Hetherington, HP; Mitchell, G; Pan, JW; Pohost, GM; Vaughan, JT; Whitaker, JN | 1 |
| Bhakoo, KK; Florian, CL; Noble, MD; Williams, SR | 1 |
| Bates, TE; Brooks, KJ; Clark, JB | 1 |
| Nowak, PJ; Oudkerk, M; Sijens, PE; van den Bent, MJ; van Dijk, P | 1 |
| Baldwin, RL; Huyghues-Despointes, BM | 1 |
| Jackson, EF; Meyers, CA | 1 |
| Amess, PN; Brown, GC; Cady, EB; Cooper, CE; D'Souza, P; Edwards, AD; Kirkbride, V; Lorek, A; Penrice, J; Reynolds, EO; Wyatt, JS; Wylezinska, M | 1 |
| Chang, L; Ernst, T; Mehringer, CM; Melchor, R | 1 |
| Bell, JD; Chong, A; Chung, YL; Hope, J; Williams, A; Williams, SC | 1 |
| Laxer, KD | 1 |
| Berger, M; Ebert, D; Hennig, J; Hohagen, F; König, A; Speck, O | 1 |
| Kavanaugh, MP; Landfear, SM; Seyfang, A | 1 |
| Alger, JR; Bonavita, S; Di Chiro, G; Duyn, JH; Lundbom, N; Raman, R; Tedeschi, G | 1 |
| Chang, S; Day, MR; Dillon, WP; Gutin, PH; Henry, RG; Huhn, SL; Larson, DA; McDermott, M; Nelson, SJ; Noworolski, SE; Prados, MD; Sneed, PK; Vigneron, DB; Wald, LL; Wara, WM | 1 |
| Burtscher, IM; Holtås, S; Ståhlberg, F | 1 |
| Boesiger, P; Duc, CO; Meier, D; Trabesinger, AH; Weber, OM | 1 |
| Hiltunen, Y; Kaartinen, J; Kauppinen, RA; Mierisová, S; Oja, JM; Usenius, JP | 1 |
| Anderson, G; Bartha, R; Canaran, G; Carr, TJ; Densmore, M; Drost, DJ; Neufeld, RW; Siddiqui, AR; Stein, MB; Williamson, PC | 1 |
| Munck, BG; Munck, LK | 1 |
| Abe, K; Fujita, N; Hirabuki, N; Nakamura, M; Terakawa, H; Watanabe, Y; Yanagihara, T | 1 |
| Green, EL; Klinman, JP; Plastino, J; Sanders-Loehr, J | 1 |
| Balashov, SP; Ebrey, TG; Gennis, RB; Maeda, A; Tomson, FL | 1 |
| Majors, AW; Mitsumoto, H; Nelson, DR; Ng, TC; Pioro, EP | 1 |
| Braun, KP; de Graaf, RA; Gooskens, RH; Nicolay, K; Tulleken, KA; van Eijsden, P; Vandertop, WP | 1 |
| Esposito, L; Mazzarella, L; Sica, F; Sorrentino, G; Vitagliano, L; Zagari, A | 1 |
| Digits, JA; Hedstrom, L; Kerr, KM; Kuperwasser, N | 1 |
| Braunová, Z; Gvozdjáková, A; Kasparová, S; Liptaj, T; Mierisová, S; Mlynárik, V; Tkác, I | 1 |
| Egestad, B; Hanson, LG; Møller, A; Sager, TN; Topp, S; Torup, L | 1 |
| Bustillo, JR; Lauriello, J; Rowland, L | 1 |
| Biessels, GJ; Braun, KP; de Graaf, RA; Gispen, WH; Nicolay, K; van Eijsden, P | 1 |
| Buijs, J; Hagman, C; Håkansson, K; Håkansson, P; Oscarsson, S; Richter, JH | 1 |
| Amend, DL; Capizzano, AA; Ezekiel, F; Gamst, AC; Maudsley, AA; Schuff, N; Weiner, MW | 1 |
| Sokół, M | 1 |
| Golding, BT; Radom, L; Smith, DM; Wetmore, SD | 1 |
| Alexander, GE; Chang, L; Huang, W; Krasuski, JS; Rapoport, SI; Schapiro, MB; Shetty, HU | 1 |
| Kobayashi, K; Miyakawa, S; Sawaoka, AB | 1 |
| Enomoto, H; Fujisaki, Y; Nakamura, T; Nakayama, Y; Takabe, T; Uozumi, N; Yamaguchi, N | 1 |
| Frey, PA; Gerratana, B; Gross, JW; Hegeman, AD | 1 |
| Blair, DF; Braun, TF | 1 |
| Ballesteros, P; Bruix, M; Cerdán, S; García-Espinosa, MA; García-Martín, ML | 1 |
| Bisschops, RH; Kappelle, LJ; Mali, WP; van der Grond, J | 1 |
| Oudkerk, M; Sijens, PE | 1 |
| Chu, GC; Ikeda-Saito, M; Li, Y; Mar, GN; Syvitski, RT | 1 |
| Chang, L; Ernst, T; Gonzalez, RG; Jarvik, JG; Ketonen, LM; Kolson, DL; Kwok, EW; Lee, PL; Lenkinski, RE; Marra, CM; Meyerhoff, DJ; Navia, BA; Richards, TL; Schifitto, G; Simpson, D; Tang, CY; Yiannoutsos, CT | 1 |
| Garavito, RM; Losey, HC; Lu, W; Mulichak, AM; Walsh, CT; Wawrzak, Z | 1 |
| BARNES, FW; ENNS, T; HENRY, SS; HILTON, MA | 1 |
| BARNES, FW; ENNS, T; HILTON, MA | 1 |
| TAGER, JM | 1 |
| SPRECHER, M; SPRINSON, DB | 1 |
| BRIGHT, H | 1 |
| HILL, J; LEACH, SJ | 1 |
| LOEB, GI; SAROFF, HA | 1 |
| Adryanczyk-Perrier, G; Burlat, B; De Lacey, AL; Dementin, S; Fernandez, VM; Guigliarelli, B; Pardo, A; Rousset, M | 1 |
| Adam, Y; Schuldiner, S; Soskine, M | 1 |
| Fukatsu, H; Hamada, K; Hirayama, M; Ishigaki, T; Katsuno, M; Okada, Y; Sobue, G; Sugiura, M; Watanabe, H | 1 |
| Dong, Z; Dreher, W; Leibfritz, D | 1 |
| Barantin, L; Montharu, J; Nadal-Desbarats, L; Pourcelot, L; Seguin, F; Serriere, S; Vial, F | 1 |
| Hurd, R; Nelson, S; Sailasuta, N; Srinivasan, R; Vigneron, D | 1 |
| Amler, E; Ettrich, R; Kubala, M; Kutý, M; Lánský, Z; Plásek, J; Schoner, W; Teisinger, J | 1 |
| Hetherington, HP; Kim, JH; Pan, JW; Spencer, DD | 1 |
| de Valk, HW; Leenders, KL; Oudkerk, M; Reijngoud, DJ; Sijens, PE; van Spronsen, FJ | 1 |
| De Keyser, J; Mostert, JP; Oudkerk, M; Sijens, PE | 1 |
| Nie, B; Stutzman, J; Xie, A | 1 |
| Godfrey, W; Hu, J; Magalhaes, A; Shen, Y; Smith, W | 1 |
| Juchem, C; Logothetis, NK; Merkle, H; Nauerth, A; Pfeuffer, J | 1 |
| Ambrosini, A; Colonnese, C; Garreffa, G; Giove, F; Guardati, M; Macrì, MA; Maraviglia, B | 1 |
| Bella, J; Humphries, MJ | 1 |
| Meiners, LC; Oudkerk, M; Rake, JP; Sijens, PE; Soorani-Lunsing, RJ; Verbruggen, KT | 1 |
| Herrmann, KA; Vorpagel, ER; Wysocki, VH | 1 |
| Häkkinen, AM; Hiltunen, Y; Kauppinen, RA; Lundbom, N; Paetau, A; Pulkkinen, J | 1 |
| Chang, KH; Han, MH; Kim, JH; Kim, K; Kwon, BJ; Na, DG; Song, IC | 1 |
| Ding, XQ; Fiehler, J; Goebell, E; Hagel, C; Heese, O; Kucinski, T; Nietz, S; Paustenbach, S; Westphal, M; Zeumer, H | 1 |
| Cady, EB; Cheong, JL; Cox, IJ; Penrice, J; Robertson, NJ; Wyatt, JS | 1 |
| Foloppe, N; Harvey, JN; Mulholland, AJ; Zurek, J | 1 |
| Grundy, RG; Lateef, S; MacPherson, L; Natarajan, K; Peet, AC; Sgouros, S | 1 |
| Hiremath, GK; Najm, IM | 1 |
| Bang, S; Bjelke, JR; Bolt, G; Fodje, M; Kragelund, BB; Olsen, OH; Persson, E; Svensson, LA | 1 |
| Compton, EL; Mindell, JA; Ryan, RM | 1 |
| Guan, L; Kaback, HR | 1 |
| Gorres, KL; Pua, KH; Raines, RT | 1 |
| Håkansson, K; Marsh, EN; Song, H; Yoon, M | 1 |
| Bala Amutha, K; Murugesan, AG | 1 |
| Tong, T; Xiaoyuan, F; Zhenwei, Y | 1 |
| Bowen, KH; Li, X; Martínez, A; Salpin, JY; Schermann, JP; Wang, H | 1 |
| Castañeda, CA; Chimenti, MS; García-Moreno E, B; Majumdar, A | 1 |
| Arheart, KL; Govind, V; Maudsley, AA; Saigal, G; Sharma, KR; Sheriff, S | 1 |
| Di Nardo, G; Gilardi, G; Giraudo, A; King, PW; Morra, S; Valetti, F | 1 |
| Gigante, AD; Lafer, B; Yatham, LN | 1 |
| Kraguljac, NV; Lahti, AC; Reid, MA; White, DM | 1 |
| Chatani, N; Misal Castro, LC | 1 |
| Clarkson, BR; Smith, HO; Weyman, PD; Yonemoto, IT | 1 |
| Bommer, M; Dobbek, H; Hennig, SE; Jeoung, JH; Lenz, O; Schäfer, C | 1 |
| Chen, G; Das, TK; Fu, Y; Jusuf, S; Krystek, SR; Ludwig, R; Tao, L; Wei, H; Yan, Y; Zeng, M | 1 |
| Bertsova, YV; Bogachev, AV; Mamedov, AM; Mamedov, MD | 1 |
| Bankhele, P; Jamil, J; Njie-Mbye, F; Ohia, S; Opere, CA; Salvi, A | 1 |
| Hong, Q; Li, S; Lian, X; Yin, C; Zhao, W | 1 |
5 review(s) available for hydrogen and aspartic acid
| Article | Year |
|---|---|
N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Humans; Hydrogen; Magnetic Resonance Spectroscopy | 1989 |
Introduction to hippocampal spectroscopy.
Topics: Aspartic Acid; Brain Diseases; Choline; Creatine; Hippocampus; Humans; Hydrogen; Image Enhancement; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Temporal Lobe | 1997 |
Clinical applications of magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Mapping; Epilepsy; Epilepsy, Frontal Lobe; Epilepsy, Temporal Lobe; Frontal Lobe; Functional Laterality; Hippocampus; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Temporal Lobe; Tomography, Emission-Computed | 1997 |
Proton magnetic resonance spectroscopy (H-MRS) studies of schizophrenia.
Topics: Aspartic Acid; Brain Chemistry; Chronic Disease; Frontal Lobe; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe | 2001 |
Magnetic resonance spectroscopy in animal models of epilepsy.
Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Choline; Creatine; Disease Models, Animal; Epilepsy; Hydrogen; Immunohistochemistry; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Rats; Sodium Isotopes | 2007 |
3 trial(s) available for hydrogen and aspartic acid
| Article | Year |
|---|---|
Hemodynamic and metabolic changes in transient ischemic attack patients: a magnetic resonance angiography and (1)H-magnetic resonance spectroscopy study performed within 3 days of onset of a transient ischemic attack.
Topics: Adult; Aged; Aspartic Acid; Brain; Cerebral Arteries; Cerebrovascular Circulation; Choline; Circle of Willis; Echo-Planar Imaging; Female; Hemodynamics; Humans; Hydrogen; Ischemic Attack, Transient; Lactic Acid; Magnetic Resonance Angiography; Magnetic Resonance Spectroscopy; Male; Middle Aged; Regional Blood Flow; Time Factors | 2002 |
A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis.
Topics: AIDS Dementia Complex; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Excitatory Amino Acid Antagonists; Feasibility Studies; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Memantine; Neuroglia; Phantoms, Imaging; Reproducibility of Results | 2003 |
Multiple regional 1H-MR spectroscopy in multiple system atrophy: NAA/Cr reduction in pontine base as a valuable diagnostic marker.
Topics: Aspartic Acid; Brain Stem; Case-Control Studies; Cerebral Cortex; Creatine; Diagnosis, Differential; Female; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple System Atrophy; Parkinson Disease; Putamen; Reference Values | 2004 |
161 other study(ies) available for hydrogen and aspartic acid
| Article | Year |
|---|---|
Incorporation of the hydrogen atoms of ethanol into amino acids in rat liver in vivo.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Deuterium; Ethanol; Female; Glutamates; Hydrogen; Liver; NAD; Proline; Rats | 1979 |
Utilization of hydrogen and formate by Campylobacter spec. under aerobic and anaerobic conditions.
Topics: Aerobiosis; Anaerobiosis; Aspartic Acid; Campylobacter; Clostridium; Fermentation; Formates; Glutamates; Hydrogen; Succinates; Water Microbiology | 1978 |
Labilization of 3-carbon hydrogens in chelated (2S)-aspartic acid and erythro- and threo-(2S)-3-methylaspartic acid.
Topics: Aspartic Acid; Chelating Agents; Cobalt; Hydrogen; Isomerism; Isotope Labeling; Magnetic Resonance Spectroscopy | 1976 |
Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Aspartic Acid; Atrophy; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; Child; Choline; Creatine; Female; Frontal Lobe; Humans; Hydrogen; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine | 1992 |
Use of a dihydrogen osmium complex as a versatile 1H NMR recognition probe.
Topics: Amino Acids; Aspartic Acid; Deoxyribonucleotides; Ethylenediamines; Glutamates; Glutamic Acid; Hydrogen; Indicators and Reagents; Ligands; Magnetic Resonance Spectroscopy; Osmium; Ribonucleotides | 1992 |
Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status.
Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cytoplasm; Gluconeogenesis; Glutamates; Glutamic Acid; Hydrogen; Hyperthyroidism; Hypothyroidism; Male; Malonates; Mitochondria, Liver; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Thyroid Gland; Urea | 1992 |
In vivo identification and monitoring of changes in rat brain glucose by two-dimensional shift-correlated 1H NMR spectroscopy.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain; Glucose; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic; Rats; Rats, Wistar | 1992 |
1H NMR study of cortex neurons and cerebellar granule cells on microcarriers and their PCA extracts: lactate production under hypoxia.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cerebral Cortex; Culture Media; Dextrans; gamma-Aminobutyric Acid; Hydrogen; Hypoxia, Brain; Lactates; Magnetic Resonance Spectroscopy; Mice; Microspheres; Neurons; Perchlorates | 1992 |
Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cerebral Infarction; Choline; Chronic Disease; Creatine; Female; Humans; Hydrogen; Image Enhancement; Inositol; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged | 1992 |
Mechanism of C-3 hydrogen exchange and the elimination of ammonia in the 3-methylaspartate ammonia-lyase reaction.
Topics: Ammonia; Ammonia-Lyases; Aspartic Acid; Clostridium; Hydrogen; Kinetics; Magnesium; Maleates; Potassium; Substrate Specificity; Tritium | 1992 |
1H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Child; Creatine; Demyelinating Diseases; Humans; Hydrogen; Magnetic Resonance Imaging; Nerve Degeneration; Neurons; Phosphorus Isotopes | 1992 |
[In vivo 1H and 31P NMR spectroscopy of the developing rat brain].
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Choline; Female; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Phosphorus; Rats; Rats, Inbred Strains; Taurine | 1992 |
Energy conservation by succinate decarboxylation in Veillonella parvula.
Topics: Acetates; Aspartic Acid; Carboxyl and Carbamoyl Transferases; Cell Division; Decarboxylation; Energy Metabolism; Fermentation; Hydrogen; Lactates; Lactic Acid; Malates; Models, Biological; Propionates; Pyruvate Carboxylase; Succinates; Succinic Acid; Transferases; Veillonella | 1992 |
Assignment of resonance in the 1H spectrum of rat brain by two-dimensional shift correlated and J-resolved NMR spectroscopy.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Chromatography, Ion Exchange; Creatine; Electron Spin Resonance Spectroscopy; Female; Fourier Analysis; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Inositol; Lactates; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains; Taurine; Threonine | 1991 |
In vivo 1H and 31P NMR spectroscopy of the developing rat brain.
Topics: Adenosine Triphosphate; Aging; Animals; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Hydrogen; Magnetic Resonance Spectroscopy; Phosphocreatine; Phosphorus; Rats; Rats, Inbred Strains | 1992 |
Spatially localized in vivo 1H magnetic resonance spectroscopy of an intracerebral rat glioma.
Topics: Animals; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Female; Glioma; Hydrogen; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Structural; Rats; Rats, Inbred F344 | 1992 |
The solution structure and conformational dynamics of tumor necrosis factor-alpha and a (Cys69----Asp; Cys101----Arg) analog as examined by IR spectroscopy and hydrogen exchange.
Topics: Animals; Arginine; Aspartic Acid; Cysteine; Deuterium; Hydrogen; Mutagenesis, Site-Directed; Protein Conformation; Spectrophotometry, Infrared; Tumor Necrosis Factor-alpha | 1991 |
The visibility of the 1H NMR signal of ethanol in the dog brain.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Creatine; Diffusion; Dogs; Ethanol; Hydrogen; Injections, Intravenous; Magnetic Resonance Spectroscopy; Time Factors | 1991 |
Localized 1H NMR spectroscopy in Canavan's disease: a report of two cases.
Topics: Aspartic Acid; Basal Ganglia; Brain; Child, Preschool; Choline; Creatine; Diffuse Cerebral Sclerosis of Schilder; Female; Humans; Hydrogen; Infant; Magnetic Resonance Spectroscopy; Male; Occipital Lobe | 1991 |
[Longitudinal change of H-1 spectroscopy in cerebral infarction].
Topics: Aged; Aspartic Acid; Brain; Cerebral Infarction; Female; Humans; Hydrogen; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 1991 |
Improved quantification of in vivo 1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fitting.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Image Enhancement; Ischemia; Liver; Magnetic Resonance Spectroscopy; Rats | 1990 |
Veratridine and other depolarizing agents counteract the inhibitory effect of Mg2+ ions on N-methyl-D-aspartate (NMDA)-induced noradrenaline release in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Amifampridine; Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Electric Stimulation; Hydrogen; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Veratridine; Veratrine | 1990 |
Proton nuclear magnetic resonance study of the B9(Asp) mutant of human insulin. Sequential assignment and secondary structure.
Topics: Amino Acid Sequence; Aspartic Acid; Humans; Hydrogen; Insulin; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation | 1991 |
Brain development: 1H magnetic resonance spectroscopy of rat brain extracts compared with chromatographic methods.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Creatine; Hydrogen; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains | 1990 |
Metabolic acidosis induced by N-methyl-D-aspartate in brain slices of the neonatal rat: 31P- and 1H-magnetic resonance spectroscopy.
Topics: Acidosis, Lactic; Animals; Aspartic Acid; Frontal Lobe; Glucose; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; N-Methylaspartate; Phosphorus Radioisotopes; Rats | 1988 |
Acute cerebral ischaemia: concurrent changes in cerebral blood flow, energy metabolites, pH, and lactate measured with hydrogen clearance and 31P and 1H nuclear magnetic resonance spectroscopy. II. Changes during ischaemia.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Gerbillinae; Hydrogen; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphocreatine; Phosphorus | 1987 |
Effect of UV radiations on amino acids. V. Ultraviolet induced changes in aqueous solution of methionine in presence or absence of hydrogen or nitrogen.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Paper; Cold Temperature; Hydrogen; Indenes; Ketones; Methionine; Nitrogen; Radiation Effects; Spectrophotometry; Sulfoxides; Time Factors; Ultraviolet Rays | 1970 |
Stereospecificity of the dihydroorotate-dehydrogenase reaction.
Topics: Asparagine; Aspartic Acid; Bacteria; Benzyl Compounds; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deuterium; Esters; Ethanol; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; NAD; Orotic Acid; Oxidation-Reduction; Oxidoreductases; Structure-Activity Relationship | 1972 |
Hot hydrogen atoms reactions of interest in molecular evolution and interstellar chemistry.
Topics: Alanine; Amines; Amino Acids; Ammonia; Aspartic Acid; Biological Evolution; Carbon Monoxide; Catalysis; Chemical Phenomena; Chemistry; Ethanol; Ethylamines; Extraterrestrial Environment; Glutamates; Glycine; Hydrogen; Leucine; Methane; Photolysis; Valine | 1974 |
High resolution nuclear magnetic resonance study of the histidine--aspartate hydrogen bond in chymotrypsin and chymotrypsinogen.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Chymotrypsinogen; Histidine; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Biology | 1972 |
Transfer of hydrogen via tricarboxylic acid cycle activity to liver aspartate and glutamate in normal rats and to liver haem in normal and in allylisopropylacetamide-treated rats.
Topics: Acetamides; Allylisopropylacetamide; Animals; Aspartic Acid; Citric Acid Cycle; Ethanol; Female; Glutamates; Glycine; Heme; Hydrogen; Liver; Malates; Propionates; Rats; Succinates; Tritium | 1973 |
Theoretical calculations on an acetic acid, 5-methylimidazole, methanol hydrogen bond network: a model charge relay system.
Topics: Acetates; Aspartic Acid; Carboxylic Acids; Chymotrypsin; Hydrogen; Hydrogen-Ion Concentration; Imidazoles; Ions; Methanol; Models, Chemical; Serine | 1974 |
Homoserine dehydrogenase-aspartokinase of Escherichia coli. Comparison of threonine saturation and enzyme conformation.
Topics: Alcohol Oxidoreductases; Aminobutyrates; Aspartic Acid; Binding Sites; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Chemical Phenomena; Chemistry; Dialysis; Escherichia coli; Feedback; Hydrogen; Hydroxybutyrates; Kinetics; Phosphotransferases; Protein Binding; Spectrophotometry; Sulfhydryl Compounds; Sulfhydryl Reagents; Threonine; Tritium; Ultraviolet Rays | 1971 |
Mechanism of action of coenzyme B 12 . Hydrogen transfer in the isomerization of -methylaspartate to glutamate.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Glutamates; Hydrogen; Isomerases; Kinetics; Mass Spectrometry; Mathematics; Models, Chemical; Vitamin B 12 | 1972 |
Hydrogen transfer between substrates and deoxyadenosylcobalamin in the glutamate mutase reaction.
Topics: Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry; Clostridium; Coenzymes; Glutamates; Hydrogen; Isomerases; Kinetics; Methods; Nucleosides; Tritium; Vitamin B 12 | 1969 |
Nuclear magnetic resonance studies of exchange reaction of alpha-hydrogen of glutamic acid catalyzed by aspartate aminotransferase.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Deuterium; Glutamates; Hydrogen; Magnetic Resonance Spectroscopy; Methods; Myocardium; Oxides; Swine; Ultracentrifugation | 1969 |
Water extrusion in biological rctions.
Topics: Antigen-Antibody Reactions; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Hydrogen; Lysine; Models, Structural; Water | 1970 |
Interctions between potassium ions and glycine transport in the yeast Saccharomyces carlsbergensis.
Topics: Aspartic Acid; Biological Transport; Carbon Isotopes; Depression, Chemical; Glucose; Glycine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Lysine; Potassium; Saccharomyces; Sodium | 1970 |
Amino-terminal-blocked tripeptide analogues of the active site of -chymotrypsin.
Topics: Acrylates; Amino Acid Sequence; Amino Acids; Aspartic Acid; Barium; Benzyl Compounds; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Formates; Furans; Glycine; Hydrogen; Hydrolysis; Hydroxides; Imidazoles; Methods; Oxidation-Reduction; Peptides; Serine | 1970 |
A high resolution structure of an inhibitor complex of the extracellular nuclease of Staphylococcus aureus. I. Experimental procedures and chain tracing.
Topics: Arginine; Aspartic Acid; Barium; Binding Sites; Calcium; Chemical Phenomena; Chemistry; Deoxyribonucleases; Glutamates; Hydrogen; Lysine; Mathematics; Methods; Models, Structural; Nucleotides; Ribonucleases; Staphylococcus; Thymine Nucleotides; Trypsin; Tyrosine; Uracil; X-Ray Diffraction | 1971 |
Tritium--hydrogen exchange of bacitracin A. Evidence for an intramolecular hydrogen bond.
Topics: Asparagine; Aspartic Acid; Bacitracin; Chemical Phenomena; Chemistry; Chromatography, Gel; Histones; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Oxidation-Reduction; Temperature; Time Factors; Tritium | 1971 |
Hydrogen pathways in mitochondria. II. The reductive amination of ketoglutarate. Analysis of pathways, stoichiometry and kinetics.
Topics: Adenosine Triphosphate; Alanine; Ammonia; Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Cell Membrane Permeability; Chromatography, Thin Layer; Glutamate Dehydrogenase; Glutamates; Hydrogen; Ketoglutaric Acids; Kinetics; Liver; Malates; Mitochondria; Rats; Succinates | 1965 |
Hydrogenolysis of benzyl esters with palladium-on-carbon catalysts.
Topics: Aspartic Acid; Benzene; Carbon; Catalysis; Hydrogen; Malates; Palladium; Succinates; Tartrates | 1965 |
Synthesis of 2,6-dioxo-3-phthalimidopiperidine-3,4,4,5,5-d, and 2,5-dioxo-3-phthalimidopyrrolidine-3,4,4-d, from L-deuterio-glutamic acid and L-deuterio-aspartic acid.
Topics: Aspartic Acid; Carbon; Chemistry, Pharmaceutical; Deuterium; Eukaryota; Glutamates; Hydrogen; Nitrogen; Piperidines; Thalidomide | 1965 |
The role of hydrogen translocating shuttles during ethanol oxidation in hepatocytes from euthyroid and hyperthyroid rats.
Topics: Alcohol Oxidoreductases; Animals; Aspartic Acid; Cycloserine; Ethanol; Gluconeogenesis; Glycerophosphates; Hydrogen; Hyperthyroidism; Liver; Malates; Male; Mitochondria, Liver; Oxidation-Reduction; Rats | 1980 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminant Analysis; Female; Glioblastoma; Glioma; Glutamates; Glutamine; Glycine; Humans; Hydrogen; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Protons | 1995 |
Homonuclear J-refocused spectral editing technique for quantification of glutamine and glutamate by 1H NMR spectroscopy.
Topics: Algorithms; Aspartic Acid; Creatine; Feasibility Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hydrogen; Image Enhancement; Magnetic Resonance Spectroscopy; Signal Processing, Computer-Assisted | 1995 |
H-1 MR spectroscopic imaging of white matter signal hyperintensities: Alzheimer disease and ischemic vascular dementia.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebral Ventricles; Choline; Creatine; Dementia; Dementia, Vascular; Female; Humans; Hydrogen; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurologic Examination | 1995 |
Brain lesions in patients with AIDS: H-1 MR spectroscopy.
Topics: Abscess; Adult; AIDS Dementia Complex; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Cryptococcosis; Diagnosis, Differential; Humans; Hydrogen; Inositol; Lactates; Leukoencephalopathy, Progressive Multifocal; Lymphoma, AIDS-Related; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sensitivity and Specificity; Toxoplasmosis, Cerebral | 1995 |
Anomalous transverse relaxation in 1H spectroscopy in human brain at 4 Tesla.
Topics: Artifacts; Aspartic Acid; Body Water; Brain; Choline; Creatine; Diffusion; Electron Spin Resonance Spectroscopy; Fourier Analysis; Humans; Hydrogen; Image Enhancement; Intracellular Fluid; Magnetic Resonance Spectroscopy; Motion; Occipital Lobe; Phosphocreatine; Signal Processing, Computer-Assisted | 1995 |
Incorporation of a phosphonium analogue of choline into the rat brain as measured by magnetic resonance spectroscopy.
Topics: Animals; Aspartic Acid; Brain; Choline; Choline Deficiency; Creatinine; Glycerylphosphorylcholine; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Weight; Myelin Sheath; Organophosphorus Compounds; Phosphatidylcholines; Phospholipids; Phosphorus Isotopes; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Tissue Extracts | 1995 |
Glucose metabolism in the developing cerebral cortex as detected by 1H(13C) nuclear magnetic resonance spectroscopy ex vivo.
Topics: Acetates; Animals; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Female; Glucose; Glutamic Acid; Hydrogen; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Oxygen; Rats | 1995 |
Proton magnetic resonance spectroscopy (1H MRS) of the hippocampal formation in schizophrenia: a pilot study.
Topics: Adult; Aspartic Acid; Female; Functional Laterality; Hippocampus; Humans; Hydrogen; Limbic System; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Schizophrenia | 1994 |
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatine; Gadolinium; Gadolinium DTPA; Glycolysis; Humans; Hydrogen; Image Enhancement; Ischemia; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Necrosis; Organometallic Compounds; Pentetic Acid; Pilot Projects | 1994 |
1H-2H exchange in the perfused rat liver metabolizing [3-13C]alanine and 2H2O as detected by multinuclear NMR spectroscopy.
Topics: Alanine; Animals; Aspartic Acid; Carbon Isotopes; Deuterium; Deuterium Oxide; Glutamic Acid; Hydrogen; Liver; Magnetic Resonance Spectroscopy; Male; Perfusion; Rats; Rats, Sprague-Dawley | 1994 |
Spectral lineshape determination by self-deconvolution.
Topics: Algorithms; Animals; Artifacts; Aspartic Acid; Brain; Computer Simulation; Fourier Analysis; Hydrogen; Image Enhancement; Magnetic Resonance Spectroscopy; Rats; Spectrum Analysis | 1995 |
Improved water suppression for localized in vivo 1H spectroscopy.
Topics: Aspartic Acid; Body Water; Brain; Cerebrospinal Fluid; Humans; Hydrogen; Image Enhancement; Magnetic Resonance Spectroscopy; Magnetics; Time Factors | 1995 |
Metabolic assessment of a neuron-enriched fraction of rat cerebrum using high-resolution 1H and 13C NMR spectroscopy.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Carbon Radioisotopes; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrogen; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Neurons; Rats | 1993 |
Measurement of GABA following GABA-transaminase inhibition by gabaculine: a 1H and 31P NMR spectroscopic study of rat brain in vivo.
Topics: 4-Aminobutyrate Transaminase; Animals; Aspartic Acid; Brain; Brain Chemistry; Creatine; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Nucleotides; Phosphates; Phosphocreatine; Phosphorus; Rats; Rats, Sprague-Dawley | 1994 |
Band-selective spin echoes for in vivo localized 1H NMR spectroscopy.
Topics: Amino Acids; Animals; Aspartic Acid; Body Water; Brain; Choline; Citrates; Citric Acid; Creatine; Hydrogen; Image Enhancement; Lactates; Lactic Acid; Lipids; Magnetic Resonance Spectroscopy; Models, Structural; Rats; Water | 1994 |
Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Choline; Cohort Studies; Creatine; Demyelinating Diseases; Humans; Hydrogen; Image Enhancement; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis; Phosphocreatine; Signal Processing, Computer-Assisted | 1994 |
Automated processing for proton spectroscopic imaging using water reference deconvolution.
Topics: Artifacts; Aspartic Acid; Body Water; Brain; Choline; Creatine; Electronic Data Processing; Fourier Analysis; Humans; Hydrogen; Image Enhancement; Lactates; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Multiple Sclerosis; Phosphocreatine; Protons; Water | 1994 |
Reduced phase encoding in spectroscopic imaging.
Topics: Adenosine Triphosphate; Animals; Artifacts; Aspartic Acid; Brain; Choline; Computer Simulation; Creatine; Fourier Analysis; Hydrogen; Image Enhancement; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Structural; Phosphates; Phosphorus; Rats | 1994 |
Childhood adrenoleukodystrophy: assessment with proton MR spectroscopy.
Topics: Adolescent; Adrenoleukodystrophy; Aspartic Acid; Child; Child, Preschool; Choline; Creatine; gamma-Aminobutyric Acid; Genetic Linkage; Glucose; Glutamates; Glutamine; Glycine; Humans; Hydrogen; Inositol; Lipids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; X Chromosome | 1993 |
Advances in proton magnetic resonance spectroscopy of the brain. A report on a workshop held in Oxford, England December 16-18, 1992.
Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Diseases; England; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Protons | 1993 |
Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types.
Topics: Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Hydrogen; Magnetic Resonance Spectroscopy; Neurons; Oligodendroglia; Rats; Rats, Wistar | 1993 |
Proton-translocating carboxyl of subunit c of F1Fo H(+)-ATP synthase: the unique environment suggested by the pKa determined by 1H NMR.
Topics: Amino Acid Sequence; Aspartic Acid; Conserved Sequence; Escherichia coli; Glutamic Acid; Hydrogen; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Mutagenesis; Point Mutation; Protein Folding; Protein Structure, Secondary; Proton-Translocating ATPases | 1995 |
Image directed proton spectroscopy of gerbil brain at 7 tesla.
Topics: Acetates; Amino Acids; Animals; Aspartic Acid; Brain; Choline; Creatine; gamma-Aminobutyric Acid; Gerbillinae; Glucose; Hydrogen; Magnetic Resonance Spectroscopy; Male; Software | 1995 |
Effect of extracellular hydrogen on organic acid utilization by the ruminal bacterium Selenomonas ruminantium.
Topics: Animals; Aspartic Acid; Culture Media; Fermentation; Fumarates; Gram-Negative Bacteria; Growth Inhibitors; Hydrogen; Lactates; Lactic Acid; Malates; Rumen | 1996 |
Reproducibility of metabolite peak areas in 1H MRS of brain.
Topics: Adult; Analysis of Variance; Artifacts; Aspartic Acid; Brain; Brain Neoplasms; Cerebrovascular Disorders; Choline; Cooperative Behavior; Craniocerebral Trauma; Creatine; Female; Humans; Hydrogen; Lactates; Magnetic Resonance Spectroscopy; Male; Middle Aged; Movement; Phantoms, Imaging; Reproducibility of Results | 1996 |
Mechanisms of H+ and Na+ changes induced by glutamate, kainate, and D-aspartate in rat hippocampal astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bicarbonates; Buffers; Carbon Dioxide; Glutamic Acid; Hippocampus; Hydrogen; Kainic Acid; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride | 1996 |
Quantitative 1H spectroscopic imaging of human brain at 4.1 T using image segmentation.
Topics: Aspartic Acid; Basal Ganglia; Brain; Cerebral Cortex; Cerebrospinal Fluid; Choline; Confidence Intervals; Creatine; Gyrus Cinguli; Humans; Hydrogen; Image Enhancement; Linear Models; Lipid Metabolism; Magnetic Resonance Imaging; Multiple Sclerosis; Parietal Lobe; Temporal Lobe; Thalamus | 1996 |
Evaluation of multiple sclerosis by 1H spectroscopic imaging at 4.1 T.
Topics: Adult; Aspartic Acid; Astrocytes; Axons; Brain; Cell Membrane; Cerebral Ventricles; Choline; Creatine; Evaluation Studies as Topic; Female; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Recurrence | 1996 |
Regional and developmental variations in metabolite concentration in the rat brain and eye: a study using 1H NMR spectroscopy and high performance liquid chromatography.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Callosum; Dipeptides; Eye; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen; Magnetic Resonance Spectroscopy; Olfactory Bulb; Oligodendroglia; Optic Nerve; Organ Specificity; Rats; Stem Cells | 1996 |
Assessment of energy metabolism in the developing brain following aglycemic hypoxia by 1H and 31P NMR.
Topics: Alanine; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Cerebral Cortex; Energy Metabolism; Female; Glucose; Hydrogen; Hypoxia; In Vitro Techniques; Kinetics; Lactates; Magnesium; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorus; Potassium; Rats; Rats, Wistar | 1996 |
1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Fourier Analysis; Gadolinium; Gadolinium DTPA; Heterocyclic Compounds; Humans; Hydrogen; Image Enhancement; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Organometallic Compounds; Pentetic Acid; Regression Analysis | 1997 |
Ion-pair and charged hydrogen-bond interactions between histidine and aspartate in a peptide helix.
Topics: Amino Acid Sequence; Aspartic Acid; Histidine; Hydrogen; Hydrogen Bonding; Molecular Sequence Data; Peptides; Protein Folding | 1997 |
Proton magnetic resonance spectroscopy of the brain during acute hypoxia-ischemia and delayed cerebral energy failure in the newborn piglet.
Topics: Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Brain; Creatine; Energy Metabolism; Humans; Hydrogen; Hypoxia, Brain; Infant, Newborn; Ischemic Attack, Transient; Kinetics; Lactates; Magnetic Resonance Spectroscopy; Phosphocreatine; Phosphorus; Reperfusion; Swine; Time Factors | 1997 |
Frontotemporal dementia and early Alzheimer disease: differentiation with frontal lobe H-1 MR spectroscopy.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Dementia; Discriminant Analysis; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Hydrogen; Inositol; Lactates; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Neuroglia; Neurons; Parietal Lobe; Protons; Sensitivity and Specificity; Temporal Lobe | 1997 |
Metabolic changes associated with vacuolation in murine models of scrapie using in vitro 1H-NMR spectroscopy.
Topics: Animals; Aspartic Acid; Brain; Hydrogen; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Reference Values; Scrapie; Vacuoles | 1996 |
1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for neuronal loss in the cingulate gyrus and the right striatum.
Topics: Adult; Aspartic Acid; Cell Count; Corpus Striatum; Female; Functional Laterality; Gyrus Cinguli; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Obsessive-Compulsive Disorder; Parietal Lobe; Severity of Illness Index | 1997 |
Aspartate 19 and glutamate 121 are critical for transport function of the myo-inositol/H+ symporter from Leishmania donovani.
Topics: Animals; Aspartic Acid; Carrier Proteins; Cell Membrane; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Inositol; Leishmania donovani; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Secondary; Recombinant Proteins; Xenopus laevis | 1997 |
Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cell Transformation, Neoplastic; Choline; Creatine; Deoxyglucose; Disease Progression; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Follow-Up Studies; Glioma; Humans; Hydrogen; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Phosphocreatine; Prognosis; Protons; Radiopharmaceuticals; Tomography, Emission-Computed | 1997 |
Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy.
Topics: Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Disease Progression; Feasibility Studies; Follow-Up Studies; Glioblastoma; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Necrosis; Neoplasm Recurrence, Local; Neoplasm, Residual; Protons; Radiation Injuries; Radiography, Interventional; Retrospective Studies; Stereotaxic Techniques; Supratentorial Neoplasms; Tomography, X-Ray Computed | 1997 |
Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Cerebral Hemorrhage; Child; Child, Preschool; Choline; Creatine; Diagnosis, Differential; Epidermal Cyst; Female; Glioma; Humans; Hydrogen; Image Enhancement; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Preoperative Care; Protons; Sensitivity and Specificity | 1997 |
Quantitative 1H MRS of the human brain in vivo based on the stimulation phantom calibration strategy.
Topics: Adolescent; Adult; Aspartic Acid; Body Water; Brain; Calibration; Cerebellum; Choline; Computer Simulation; Creatine; Frontal Lobe; Hippocampus; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Models, Biological; Occipital Lobe; Parietal Lobe; Phantoms, Imaging; Phosphocreatine; Protons; Reproducibility of Results; Signal Processing, Computer-Assisted | 1998 |
Automated quantification of human brain metabolites by artificial neural network analysis from in vivo single-voxel 1H NMR spectra.
Topics: Aspartic Acid; Automation; Brain; Choline; Computer Simulation; Creatine; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Neural Networks, Computer; Reference Values | 1998 |
A short echo 1H spectroscopy and volumetric MRI study of the corpus striatum in patients with obsessive-compulsive disorder and comparison subjects.
Topics: Adult; Aspartic Acid; Cell Count; Corpus Striatum; Female; Functional Laterality; Humans; Hydrogen; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Obsessive-Compulsive Disorder | 1998 |
Effects of pH changes on systems ASC and B in rabbit ileum.
Topics: Amino Acid Transport Systems; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Chlorides; Female; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Ileum; Jejunum; Kinetics; Microvilli; Rabbits; Serine; Sodium | 1999 |
Proton magnetic resonance spectroscopy (1H MRS) in patients with sporadic cerebellar degeneration.
Topics: Adult; Aged; Aspartic Acid; Atrophy; Cerebellar Diseases; Cerebellum; Choline; Creatine; Disease Progression; Female; Frontal Lobe; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple System Atrophy; Neurodegenerative Diseases; Phosphocreatine; Protons; Putamen | 1999 |
An unexpected role for the active site base in cofactor orientation and flexibility in the copper amine oxidase from Hansenula polymorpha.
Topics: Amine Oxidase (Copper-Containing); Ammonia; Asparagine; Aspartic Acid; Binding Sites; Carbon; Deuterium; Enzyme Activation; Glutamic Acid; Hydrogen; Methylamines; Mutagenesis, Site-Directed; Oxygen; Pichia; Schiff Bases; Solvents; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Substrate Specificity; Viscosity | 1999 |
Chromophore-protein-water interactions in the L intermediate of bacteriorhodopsin: FTIR study of the photoreaction of L at 80 K.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Bacteriorhodopsins; Cold Temperature; Halobacterium salinarum; Hydrogen; Models, Molecular; Oxygen; Photochemistry; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Threonine; Tryptophan; Valine; Water | 1999 |
1H-MRS evidence of neurodegeneration and excess glutamate + glutamine in ALS medulla.
Topics: Adult; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Female; Glutamic Acid; Glutamine; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Medulla Oblongata; Middle Aged; Nerve Degeneration; Reference Values | 1999 |
Cerebral metabolism in experimental hydrocephalus: an in vivo 1H and 31P magnetic resonance spectroscopy study.
Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Energy Metabolism; Hydrocephalus; Hydrogen; Lactic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphates; Phosphorus; Rats; Rats, Wistar; Reference Values | 1999 |
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: hydration and sterochemical analysis.
Topics: Amides; Amino Acid Sequence; Animals; Anisotropy; Aspartic Acid; Binding Sites; Cattle; Crystallization; Crystallography, X-Ray; Glutamine; Histidine; Hydrogen; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonuclease, Pancreatic; Solvents; Sulfates; Water | 2000 |
Asp338 controls hydride transfer in Escherichia coli IMP dehydrogenase.
Topics: Alkylation; Aspartic Acid; Catalysis; Catalytic Domain; Deuterium; Escherichia coli; Hydrogen; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Chemical; Mutation | 2000 |
Metabolic changes in rat brain after prolonged ethanol consumption measured by 1H and 31P MRS experiments.
Topics: Adenosine Triphosphate; Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; Astrocytes; Brain; Choline; Energy Metabolism; Hydrogen; Inositol; Magnesium; Magnetic Resonance Spectroscopy; Male; Phosphates; Phosphocreatine; Phosphorus; Rats; Rats, Wistar; Reference Values | 2000 |
Evaluation of CA1 damage using single-voxel 1H-MRS and un-biased stereology: Can non-invasive measures of N-acetyl-asparate following global ischemia be used as a reliable measure of neuronal damage?
Topics: Animals; Aspartic Acid; Biomarkers; Brain; Chromatography, High Pressure Liquid; Gerbillinae; Hippocampus; Hydrogen; Ischemic Attack, Transient; Magnetic Resonance Spectroscopy; Male; Neurons; Reproducibility of Results; Time Factors | 2001 |
Cerebral metabolism in streptozotocin-diabetic rats: an in vivo magnetic resonance spectroscopy study.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Blood Glucose; Body Weight; Brain; Choline; Creatine; Diabetes Mellitus, Experimental; Energy Metabolism; Hydrogen; Lactates; Magnetic Resonance Spectroscopy; Male; Phosphates; Phosphocreatine; Phosphorus; Rats; Rats, Wistar; Reference Values; Time Factors | 2001 |
Inter- and intra-molecular migration of peptide amide hydrogens during electrospray ionization.
Topics: Algorithms; Amides; Aspartic Acid; Deuterium; Fourier Analysis; Hydrogen; Oligopeptides; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2001 |
Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Diseases; Choline; Creatine; Female; Humans; Hydrogen; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Signal Processing, Computer-Assisted | 2001 |
In vivo 1H MR spectra analysis by means of second derivative method.
Topics: Adult; Amino Acids; Aspartic Acid; Brain; Choline; Creatine; Deuterium Oxide; Energy Metabolism; Female; Glucose; Glutamic Acid; Humans; Hydrogen; Inositol; Likelihood Functions; Magnetic Resonance Spectroscopy; Male; Normal Distribution; Reference Values; Reproducibility of Results | 2001 |
Interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate: a distinctive B(12)-dependent carbon-skeleton rearrangement.
Topics: Aspartic Acid; Catalysis; Clostridium; Cobamides; Deoxyadenosines; Electron Spin Resonance Spectroscopy; Glutamic Acid; Glycine; Hydrogen; Intramolecular Transferases; Methylmalonyl-CoA Mutase; Models, Chemical; Molecular Structure; Oxidation-Reduction; Propylamines; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2001 |
Brain metabolite concentration and dementia severity in Alzheimer's disease: a (1)H MRS study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Dementia; Female; Humans; Hydrogen; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Regression Analysis | 2001 |
Amino acid synthesis from CO-N2 and CO-N2-H2 gas mixtures via complex organic compounds.
Topics: Amino Acids; Aspartic Acid; Carbon Monoxide; Electricity; Gas Chromatography-Mass Spectrometry; Glycine; Hydrogen; Nitrogen; Water | 1999 |
Residue aspartate-147 from the third transmembrane region of Na(+)/H(+) antiporter NhaB of Vibrio alginolyticus plays a role in its activity.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Culture Media; Escherichia coli Proteins; Hydrogen; Membrane Proteins; Sodium Chloride; Sodium-Hydrogen Exchangers; Vibrio | 2001 |
Dehydration is catalyzed by glutamate-136 and aspartic acid-135 active site residues in Escherichia coli dTDP-glucose 4,6-dehydratase.
Topics: Aspartic Acid; Binding Sites; Catalysis; Deoxyglucose; Escherichia coli; Glutamic Acid; Hydro-Lyases; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Protons; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2001 |
Targeted disulfide cross-linking of the MotB protein of Escherichia coli: evidence for two H(+) channels in the stator Complex.
Topics: Aspartic Acid; Bacterial Proteins; Cell Membrane; Cross-Linking Reagents; Cysteine; Dimerization; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ethylmaleimide; Hydrogen; Immunoblotting; Iodine; Ions; Mesylates; Models, Biological; Mutation; Oxygen; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons | 2001 |
Hydrogen turnover and subcellular compartmentation of hepatic [2-(13)C]glutamate and [3-(13)C]aspartate as detected by (13)C NMR.
Topics: Animals; Aspartic Acid; Citric Acid Cycle; Cytosol; Glutamic Acid; Hydrogen; Kinetics; Liver; Magnetic Resonance Spectroscopy; Male; Mice; Mitochondria; Models, Biological; Models, Chemical; Perfusion; Protein Binding; Time Factors; Water | 2002 |
1H chemical shift imaging characterization of human brain tumor and edema.
Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Choline; Creatine; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 2002 |
Solution 1H NMR investigation of the active site molecular and electronic structures of substrate-bound, cyanide-inhibited HmuO, a bacterial heme oxygenase from Corynebacterium diphtheriae.
Topics: Animals; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Corynebacterium diphtheriae; Crystallography, X-Ray; Cyanides; Heme; Heme Oxygenase (Decyclizing); Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Ligands; Magnetic Resonance Spectroscopy; Protein Binding; Protons; Water | 2003 |
Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Glycosyltransferases; Hydrogen; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serine; Substrate Specificity; Transaminases; Vancomycin | 2003 |
Mechanisms in enzymatic transamination; rate of exchange of the hydrogen of aspartate.
Topics: Aspartic Acid; Behavior; Hydrogen | 1954 |
Mechanisms in enzymatic transamination; effect of alpha-ketoglutarate concentration on the rate of exchange of the hydrogen of aspartate.
Topics: Aspartic Acid; Hydrogen; Keto Acids; Ketoglutaric Acids; Ketones | 1956 |
SYNTHESIS OF GLUTAMATE FROM ALPHA-OXOGLUTARATE AND AMMONIA IN RAT-LIVER MITOCHONDRIA. III. MALATE AS HYDROGEN DONOR.
Topics: Adenosine Triphosphate; Ammonia; Amobarbital; Anti-Bacterial Agents; Aspartic Acid; Dinitrophenols; Enzyme Inhibitors; Glutamates; Glutamic Acid; Hydrogen; Ketoglutaric Acids; Liver; Malates; Mitochondria; Mitochondria, Liver; NAD; Oligomycins; Pharmacology; Rats; Research | 1963 |
THE STEREOCHEMISTRY OF THE GLUTAMATE MUTASE REACTION.
Topics: Aspartic Acid; Bromine; Chemical Phenomena; Chemistry; Chloramines; Clostridium; Deuterium; Glutamates; Hydrogen; Intramolecular Transferases; Isomerases; Metabolism; Proteus; Research; Succinates | 1964 |
THE MECHANISM OF THE BETA-METHYLASPARTASE REACTION.
Topics: Ammonia-Lyases; Aspartic Acid; Calcium; Chemical Phenomena; Chemistry; Deuterium; Enzyme Inhibitors; Hydrogen; Hydrogen-Ion Concentration; Ions; Lyases; Magnesium; Research; Silver; Sulfhydryl Compounds | 1964 |
HYDROGEN EXCHANGE AT CARBON-HYDROGEN SITES DURING ACID OR ALKALINE TREATMENT OF PROTEINS.
Topics: Amino Acids; Aspartic Acid; Carbon; Chemical Phenomena; Chemistry; Chromatography; Cystine; Glycine; Hydrogen; Insulin; Keratins; Muramidase; Proteins; Radiometry; Research; Ribonucleases; Serine; Threonine; Tritium | 1964 |
CHLORIDE- AND HYDROGEN-ION BINDING TO RIBONUCLEASE.
Topics: Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chlorides; Glutamates; Histidine; Hydrogen; Lysine; Research; Ribonucleases; Valine | 1964 |
A glutamate is the essential proton transfer gate during the catalytic cycle of the [NiFe] hydrogenase.
Topics: Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Desulfovibrio; Electron Spin Resonance Spectroscopy; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Hydrogenase; Kinetics; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Oxygen; Plasmids; Protons; Spectroscopy, Fourier Transform Infrared; Time Factors; X-Ray Diffraction | 2004 |
Direct evidence for substrate-induced proton release in detergent-solubilized EmrE, a multidrug transporter.
Topics: Antiporters; Aspartic Acid; Biological Transport; Cell Membrane; Detergents; Dicyclohexylcarbodiimide; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Ions; Kinetics; Membrane Proteins; Models, Biological; Plasmids; Protein Binding; Protons | 2004 |
Experimental method to eliminate frequency modulation sidebands in localized in vivo 1H MR spectra acquired without water suppression.
Topics: Animals; Artifacts; Aspartic Acid; Brain Chemistry; Hydrogen; Image Enhancement; Magnetic Resonance Spectroscopy; Phantoms, Imaging; Protons; Rats; Subtraction Technique; Water | 2004 |
A newborn piglet study of moderate hypoxic-ischemic brain injury by 1H-MRS and MRI.
Topics: Animals; Animals, Newborn; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabolism; Hydrogen; Hydrogen-Ion Concentration; Hypoxia-Ischemia, Brain; Ischemic Attack, Transient; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Phosphocreatine; Phosphorus Isotopes; Radiopharmaceuticals; Severity of Illness Index; Stroke; Swine | 2004 |
A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain.
Topics: Aspartic Acid; Brain; Dipeptides; Female; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Phantoms, Imaging; Protons; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted | 2004 |
The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Genetic Vectors; Glutamic Acid; Glutathione Transferase; Hydrogen; Hydrogen Bonding; Hydrolysis; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Nucleotides; Point Mutation; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Sodium-Potassium-Exchanging ATPase; Software; Spectrophotometry; Temperature | 2004 |
1H and 31P spectroscopic imaging of epilepsy: spectroscopic and histologic correlations.
Topics: Adult; Amygdala; Aspartic Acid; Brain; Choline; Creatine; Epilepsy; Epilepsy, Temporal Lobe; Female; Functional Laterality; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Neurons; Phosphocreatine; Phosphorus | 2004 |
1H MR chemical shift imaging detection of phenylalanine in patients suffering from phenylketonuria (PKU).
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Cerebral Ventricles; Choline; Creatine; Female; Humans; Hydrogen; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Phenylalanine; Phenylketonurias | 2004 |
1H Magnetic resonance spectroscopy of the internal capsule in human brain: a feasibility study to detect lactate following contralateral motor activity.
Topics: Adenosine Triphosphate; Adult; Aspartic Acid; Astrocytes; Axons; Choline; Creatine; Energy Metabolism; Feasibility Studies; Female; Glutamic Acid; Glycogen; Hand Strength; Humans; Hydrogen; Inositol; Internal Capsule; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Motor Activity | 2005 |
A vibrational spectral maker for probing the hydrogen-bonding status of protonated Asp and Glu residues.
Topics: Aspartic Acid; Bacterial Proteins; Biophysics; Carbon; Crystallography, X-Ray; Glutamic Acid; Hydrogen; Hydrogen Bonding; Models, Molecular; Oxygen; Photoreceptors, Microbial; Protein Conformation; Protons; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thermodynamics; Vibration | 2005 |
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioblastoma; Glioma; Gliosarcoma; Humans; Hydrogen; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Protons | 2005 |
High-field localized 1H NMR spectroscopy in the anesthetized and in the awake monkey.
Topics: Anesthesia, General; Animals; Artifacts; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dipeptides; Glutamic Acid; Glutamine; Glutathione; Hydrogen; Image Enhancement; Inositol; Lactic Acid; Macaca mulatta; Magnetic Resonance Spectroscopy; Phosphocreatine; Stereoisomerism; Taurine; Wakefulness | 2004 |
In vivo quantitative 1H MRS of cerebellum and evaluation of quantitation reproducibility by simulation of different levels of noise and spectral resolution.
Topics: Adult; Artifacts; Aspartic Acid; Body Water; Cerebellum; Choline; Creatine; Dipeptides; Female; Glutamic Acid; Glutamine; Humans; Hydrogen; Image Enhancement; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Neuropeptides | 2004 |
Calpha-H...O = C hydrogen bonds contribute to the specificity of RGD cell-adhesion interactions.
Topics: Arginine; Aspartic Acid; Cell Adhesion; Cell Communication; Extracellular Matrix; Hydrogen; Hydrogen Bonding; Integrins; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Oligopeptides; Peptides; Protein Binding; Protein Conformation; Stereoisomerism | 2005 |
1H chemical shift imaging of the brain in guanidino methyltransferase deficiency, a creatine deficiency syndrome; guanidinoacetate accumulation in the gray matter.
Topics: Aspartic Acid; Brain Chemistry; Child, Preschool; Choline; Creatine; Glutamic Acid; Glycine; Guanidinoacetate N-Methyltransferase; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Syndrome | 2005 |
Computational investigation and hydrogen/deuterium exchange of the fixed charge derivative tris(2,4,6-trimethoxyphenyl) phosphonium: implications for the aspartic acid cleavage mechanism.
Topics: Amino Acid Sequence; Aspartic Acid; Computational Biology; Cyclotrons; Deuterium; Hydrogen; Molecular Sequence Data; Organophosphorus Compounds; Peptides; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared | 2005 |
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glioblastoma; Glioma; Humans; Hydrogen; Image Interpretation, Computer-Assisted; Image Processing, Computer-Assisted; Lactic Acid; Lipids; Magnetic Resonance Imaging; Oligodendroglioma; Phosphocreatine | 2005 |
3T 1H-MR spectroscopy in grading of cerebral gliomas: comparison of short and intermediate echo time sequences.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Echo-Planar Imaging; Female; Glioma; Humans; Hydrogen; Image Enhancement; Inositol; Lactates; Lipids; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Time Factors | 2006 |
Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
Topics: Adult; Aged; Anisotropy; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Size; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Echo-Planar Imaging; Female; Glioma; Humans; Hydrogen; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Neurons; Oligodendroglioma | 2006 |
Proton MR spectroscopy in neonates with perinatal cerebral hypoxic-ischemic injury: metabolite peak-area ratios, relaxation times, and absolute concentrations.
Topics: Aspartic Acid; Birth Injuries; Body Water; Brain; Brain Chemistry; Child Development; Choline; Creatine; Follow-Up Studies; Gestational Age; Humans; Hydrogen; Hypoxia-Ischemia, Brain; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphocreatine; Prognosis; Protons; Thalamus | 2006 |
Mechanisms of reaction in cytochrome P450: Hydroxylation of camphor in P450cam.
Topics: Aspartic Acid; Camphor; Camphor 5-Monooxygenase; Hydrogen; Hydroxylation; Oxygen; Pseudomonas putida; Thermodynamics | 2006 |
Short echo time 1 H magnetic resonance spectroscopy of childhood brain tumours.
Topics: Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Female; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Male; Retrospective Studies; Time Factors | 2007 |
Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity.
Topics: Aspartic Acid; Calcium; Crystallography, X-Ray; Factor VIIa; Glutamic Acid; Humans; Hydrogen; Hydrogen Bonding; Models, Molecular; Mutation; Protein Binding; Protein Structure, Tertiary; Static Electricity; Thromboplastin; Time Factors | 2008 |
Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii.
Topics: Amino Acid Transport Systems; Amino Acids; Aspartic Acid; Biological Transport; Cells, Cultured; Excitatory Amino Acid Transporter 1; Glutamic Acid; Hydrogen; Kinetics; Liposomes; Potassium; Pyrococcus horikoshii; Sodium; Substrate Specificity | 2009 |
Properties of a LacY efflux mutant.
Topics: Amino Acid Substitution; Aspartic Acid; Biological Transport, Active; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Hydrogen; Lactose; Membrane Transport Proteins; Mutagenesis, Site-Directed; Protein Binding; Protein Transport | 2009 |
Stringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylase.
Topics: Alanine; Amino Acid Motifs; Aspartic Acid; Carbon; Catalysis; Catalytic Domain; Collagen; Glycine; Heme; Histidine; Humans; Hydrogen; Iron; Ligands; Procollagen-Proline Dioxygenase | 2009 |
Hydrogen tunneling in adenosylcobalamin-dependent glutamate mutase: evidence from intrinsic kinetic isotope effects measured by intramolecular competition.
Topics: Aspartic Acid; Cobamides; Deoxyadenosines; Deuterium; Hydrogen; Intramolecular Transferases; Kinetics; Models, Molecular; Temperature; Thermodynamics | 2010 |
Biological hydrogen production by the algal biomass Chlorella vulgaris MSU 01 strain isolated from pond sediment.
Topics: Alanine; Anaerobiosis; Aspartic Acid; Biomass; Bioreactors; Carbon; Chlorella vulgaris; Citric Acid; Culture Media; Cysteine; Fermentation; Geologic Sediments; Glucose; Hydrogen; Hydrogen-Ion Concentration; Mannitol; Pyruvic Acid; Succinic Acid | 2011 |
1H-MR spectroscopy changes in transient ischemic attack patients and their correlation with perfusion-weighted imaging.
Topics: Aged; Aspartic Acid; Brain; Cerebrovascular Circulation; Choline; Creatine; Female; Humans; Hydrogen; Ischemic Attack, Transient; Lactic Acid; Magnetic Resonance Angiography; Magnetic Resonance Spectroscopy; Male; Middle Aged; Time Factors | 2010 |
Negative ion photoelectron spectroscopy of the copper-aspartic acid anion and its hydrated complexes.
Topics: Algorithms; Anions; Aspartic Acid; Copper; Electrons; Hydrogen; Nitrogen; Photoelectron Spectroscopy; Quantum Theory; Solvents; Water | 2010 |
Structural origins of high apparent dielectric constants experienced by ionizable groups in the hydrophobic core of a protein.
Topics: Aspartic Acid; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Lysine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Models, Molecular; Protein Conformation; Static Electricity; Thermodynamics | 2011 |
Comprehensive evaluation of corticospinal tract metabolites in amyotrophic lateral sclerosis using whole-brain 1H MR spectroscopy.
Topics: Adult; Amyotrophic Lateral Sclerosis; Aspartic Acid; Brain; Choline; Creatine; Humans; Hydrogen; Magnetic Resonance Imaging; Male; Middle Aged; Pyramidal Tracts; Severity of Illness Index | 2012 |
Site saturation mutagenesis demonstrates a central role for cysteine 298 as proton donor to the catalytic site in CaHydA [FeFe]-hydrogenase.
Topics: Aspartic Acid; Catalytic Domain; Clostridium acetobutylicum; Codon; Cysteine; DNA; Escherichia coli; Gene Library; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrogenase; Iron-Sulfur Proteins; Kinetics; Mutagenesis; Oxidation-Reduction; Oxygen; Plasmids; Protein Structure, Tertiary; Protons | 2012 |
(1)H-MRS of hippocampus in patients after first manic episode.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Neurons; Prospective Studies; Time Factors; Young Adult | 2014 |
Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia.
Topics: Adult; Aspartic Acid; Biomarkers; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multimodal Imaging; Schizophrenia; Young Adult | 2013 |
Palladium(II)-catalyzed ortho-C-H arylation/alkylation of N-benzoyl α-amino ester derivatives.
Topics: Alkylation; Aspartic Acid; Carbon; Catalysis; Esters; Glycine; Hydrogen; Palladium | 2014 |
A broad survey reveals substitution tolerance of residues ligating FeS clusters in [NiFe] hydrogenase.
Topics: Alteromonas; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Biofuels; Hydrogen; Hydrogenase; Iron; Molecular Structure; Mutagenesis, Site-Directed; Photosynthesis; Sulfur Compounds | 2014 |
Structure of an Actinobacterial-Type [NiFe]-Hydrogenase Reveals Insight into O2-Tolerant H2 Oxidation.
Topics: Aspartic Acid; Atmosphere; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cupriavidus necator; Hydrogen; Hydrogenase; Models, Molecular; Oxidation-Reduction; Oxygen; Protein Multimerization | 2016 |
Isomerization and Oxidation in the Complementarity-Determining Regions of a Monoclonal Antibody: A Study of the Modification-Structure-Function Correlations by Hydrogen-Deuterium Exchange Mass Spectrometry.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antigen-Antibody Reactions; Aspartic Acid; CHO Cells; Complementarity Determining Regions; Cricetinae; Cricetulus; Deuterium; Deuterium Exchange Measurement; Enzyme-Linked Immunosorbent Assay; Hydrogen; Isomerism; Kinetics; Mass Spectrometry; Methionine; Oxidation-Reduction; Protein Structure, Tertiary; Recombinant Proteins | 2016 |
A single mutation converts bacterial Na(+) -transporting rhodopsin into an H(+) transporter.
Topics: Aspartic Acid; Escherichia coli; Flavobacteriaceae; Glutamic Acid; Hydrogen; Ion Transport; Ions; Membrane Transport Proteins; Mutation; Rhodopsins, Microbial; Sodium | 2016 |
Comparative Effects of Hydrogen Sulfide-Releasing Compounds on [
Topics: Animals; Aspartic Acid; Cattle; Cysteine; D-Aspartic Acid; Hydrogen; Hydrogen Sulfide; Retina; Sulfides | 2018 |
Application of Hydrogen Proton Magnetic Resonance Technology Combined with Brain Neurometabolite Analysis in the Treatment of Cognitive Impairment Caused by Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Aspartic Acid; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Female; Humans; Hydrogen; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Protons; Treatment Outcome | 2020 |