hydrochlorothiazide has been researched along with verapamil in 84 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 15 (17.86) | 18.7374 |
1990's | 21 (25.00) | 18.2507 |
2000's | 30 (35.71) | 29.6817 |
2010's | 17 (20.24) | 24.3611 |
2020's | 1 (1.19) | 2.80 |
Authors | Studies |
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Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S | 1 |
Topliss, JG; Yoshida, F | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Avdeef, A; Tam, KY | 1 |
Akamatsu, M | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bauer, D; Fischer, S; Greif, D; Hauser, C; Hauser, S; Jäckel, E; Lohse, M; Löser, R; Ludwig, FA; Pietsch, M; Pietzsch, J; Pisabarro, MT; Pufe, J; Ruiz-Gómez, G; Wodtke, R; Wong, A | 1 |
Bakris, GL; Barnhill, BW; Sadler, R | 1 |
Allen, RP; Hienz, RD; Kaminski, BJ; Sannerud, CA; Spear, DJ; Turkkan, JS | 1 |
Allen, RP; Hienz, RD; Turkkan, JS | 1 |
Distler, A; Holzgreve, H; Michaelis, J; Philipp, T; Wellek, S | 2 |
Babaian, AS; Dzhandzhapanian, AZ; Gurgenian, SV; Mikaelian, ES | 1 |
Peter, JH; Podszus, Th; Völger, KD; Zilles, P | 1 |
Hienz, RD; Turkkan, JS | 1 |
Holzgreve, H; Middeke, M | 1 |
Bluemner, E; Letzel, H | 1 |
Gries, J; Kretzschmar, R; Neumann, BW | 1 |
Lehtonen, A; Marniemi, J; Miilunpalo, S; Saarinen, R | 1 |
Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W | 1 |
Laragh, JH; Nicholson, JP; Resnick, LM | 1 |
MacGregor, GA; Markandu, ND; Singer, DR | 1 |
Fonteles, MC; Gadelha, MG; Menezes, AM; Rao, VS | 1 |
Klein, MD; Weiner, DA | 1 |
Gordin, A; Lehtonen, A; Salo, H | 1 |
Conradi, EC; Cowart, TD; Hughes, GS | 1 |
Dimitrov, D | 1 |
Duraković, Z; Gasparović, V; Gjurasin, M; Ivanović, D; Plavsić, F | 1 |
Gordin, A; Lehtonen, A | 1 |
de Oliveira, JM | 1 |
de Moraes, CA; Mourão, AM; Peixoto, RL; Pimentel Filho, P; Reinert, MI | 1 |
Rakette, S; Reinfrank, J; Schiemann, J; von Manteuffel, GE; Woll, EM | 1 |
Catalano, M; Libretti, A | 1 |
Chrysant, SG; Fox, AA; Stimpel, M | 1 |
Klaus, D | 1 |
Anthony, SE; Bierbrier, GS; Brown, JE; Feldman, RD; Freeman, DJ | 1 |
Chrysant, SG; Stimpel, M | 1 |
Allen, LV; Erickson, MA | 1 |
de Leeuw, PW; Notter, T; Zilles, P | 1 |
Novrit, BA; Punzi, HA | 1 |
Fernández, R; Garrido, J; Molinero, E; Murga, N; Sagastagoitia, JD | 1 |
Black, HR; Elliott, WJ; Fakouhi, TD; Grambsch, P; Grandits, G; Grimm, RH; Hansson, L; Lacoucière, Y; Muller, J; Neaton, JD; Sleight, P; Weber, MA; White, WB; Williams, G; Wittes, J; Zanchetti, A | 1 |
Belz, GG; Breithaupt-Grögler, K; Gerhardt, G; Lehmann, G; Notter, T | 1 |
Cifková, R; Compagnone, D; Hejl, Z; Nakov, R; Novozámská, E; Petrzílková, Z; Poledne, R; Stávek, P | 1 |
Candy, GP; Den Hond, E; Libhaber, C; Libhaber, E; Radevski, IV; Sareli, P; Skudicky, D; Staessen, JA; Valtchanova, ZP; Wang, JG | 1 |
Abrignani, MG; Barbagallo, M; Dominguez, LJ; Nardi, E; Novo, G; Novo, S; Strano, A | 1 |
Cremaschi, D; Garavaglia, M; Meyer, G; Porta, C; Sironi, C | 1 |
Aamar, S; Ben-Ishay, D; Bursztyn, M; Ghanem, J; Perk, G | 1 |
Fernández, R; Garrido, J; Puig, JG; Redon, J; Rodríguez-Pérez, JC | 1 |
Candy, G; Libhaber, E; Radevski, I; Sareli, P; Skudicky, D; Staessen, JA; Thijs, L; Tshele, E; Valtchanova, Z; Wang, JG | 1 |
Armenteros, S; Fernández González, R; Garrido, J; Goicolea, I; Martínez, JM; Moreno Carretero, E; Piniés, J | 1 |
Bakris, GL; Bristol, HA; Cangiano, JL; Cohen, JD; Cooper-DeHoff, RM; Erdine, S; Garcia-Barreto, D; Handberg, EM; Keltai, M; Kolb, HR; Kowey, P; Mancia, G; Marks, RG; Messerli, FH; Parmley, WW; Pepine, CJ | 1 |
Flack, JM | 1 |
Williams, B | 1 |
Diethelm, M; Joerger, M | 1 |
Panchagnula, R; Varma, MV | 1 |
Cooper-DeHoff, R; Elliott, WJ; Hewkin, AC; Kupfer, S; Pepine, CJ | 1 |
Bakris, GL; Cohen, JD; Cooper-Dehoff, R; Erdine, S; Hewkin, AC; Kupfer, S; Messerli, FH; Pepine, CJ | 1 |
Grimm, E; Herrmann, D; Kintscher, U; Scholze, J; Unger, T | 1 |
Celebi, O; Kilic, T; Komsuoglu, B; Kozdag, G; Sahin, T; Ural, D; Ural, E | 1 |
Benetos, A; Champion, A; Coca, A; Cooper-DeHoff, RM; Messerli, FH; Pepine, CJ; Zhou, Q | 1 |
Bacher, P; Bakris, G; Champion, A; Molitch, M; Sarafidis, P; Sowers, JR; Zhou, Q | 1 |
Bakris, GL; Champion, A; Cooper-Dehoff, RM; Kupfer, S; Pepine, CJ; Zhou, Q | 1 |
Champion, A; Cooper-DeHoff, RM; Handberg, EM; Legler, UF; Mancia, G; Pepine, CJ; Zhou, Q | 1 |
Chen, Y; Gao, MY; Gao, Q; Liao, XH; Wang, JJ | 1 |
Koester, LS; Kratz, JM; Simões, CM; Teixeira, MR | 1 |
Brumback, BA; Cooper-Dehoff, RM; Delaney, JA; Gerhard, T; Johnson, JA; Pepine, CJ; Shuster, J; Winterstein, AG | 1 |
Bailey, KR; Beitelshees, AL; Boerwinkle, EA; Chapman, AB; Cooper-DeHoff, RM; Del-Aguila, JL; Gong, Y; Gums, JG; Johnson, JA; Karnes, JH; Langaee, TY; McDonough, CW; Pepine, CJ; Turner, ST; Vo, TT | 1 |
Bailey, KR; Beitelshees, AL; Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Gawronski, BE; Gong, Y; Gums, JG; Johnson, JA; Langaee, TY; Liggett, SB; Lobmeyer, MT; Pepine, CJ; Turner, ST; Vandell, AG | 1 |
Bailey, KR; Beitelshees, AL; Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Gong, Y; Gums, JG; Johnson, JA; Kubo, M; Magvanjav, O; McDonough, CW; Pepine, CJ; Tanaka, T; Turner, ST | 1 |
Cooper-DeHoff, RM; Dasa, O; Gong, Y; Handberg, E; Howard, G; Pepine, CJ; Smith, SM | 1 |
3 review(s) available for hydrochlorothiazide and verapamil
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment of angina pectoris and hypertension with sustained-release calcium channel-blocking drugs.
Topics: Angina Pectoris; Biological Availability; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Verapamil | 1987 |
Protection against stroke and dementia: an update on the latest clinical trial evidence.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Cognition; Dementia; Hydrochlorothiazide; Ramipril; Stroke; Tetrazoles; Verapamil | 2004 |
31 trial(s) available for hydrochlorothiazide and verapamil
Article | Year |
---|---|
Treatment of arterial hypertension in diabetic humans: importance of therapeutic selection.
Topics: Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Dipeptides; Drug Combinations; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Proteinuria; Renal Circulation; Verapamil | 1992 |
Hydrochlorothiazide and verapamil in the treatment of hypertension. The Verapamil Versus Diuretic (VERDI) Trial Research Group.
Topics: Adult; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Verapamil | 1991 |
Concomitant considerations in long-term antihypertensive treatment.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Lipid Metabolism; Male; Middle Aged; Time Factors; Verapamil | 1990 |
Dose-response curves in antihypertensive combination therapy: results of a controlled clinical trial.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Triamterene; Verapamil | 1990 |
Verapamil versus hydrochlorothiazide in the treatment of hypertension: results of long term double blind comparative trial. Verapamil versus Diuretic (VERDI) Trial Research Group.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Verapamil | 1989 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Nitrendipine; Proline; Renin; Renin-Angiotensin System; Spironolactone; Verapamil | 1985 |
[Verapamil-hydrochlorothiazide vs. metoprolol-hydrochlorothiazide. Trial in hypertensive patients].
Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Verapamil | 1981 |
[Effectiveness and tolerance of combined verapamil retard and hydrochlorothiazide. Results of a double-blind, randomized study].
Topics: Adult; Aged; Antihypertensive Agents; Austria; Delayed-Action Preparations; Double-Blind Method; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Verapamil | 1995 |
Lipid profile during antihypertensive treatment. The SLIP Study Group. Study on Lipids with Isoptin Press.
Topics: Aged; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Drug Therapy, Combination; Electrocardiography; Enalapril; Female; Heart Conduction System; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Verapamil | 1993 |
Comparison of moexipril, a new ACE inhibitor, to verapamil-SR as add-on therapy to low dose hydrochlorothiazide in hypertensive patients.
Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Renin; Tetrahydroisoquinolines; Verapamil | 1995 |
Beta-adrenergic responsiveness is regulated selectively in hypertension.
Topics: Adult; Blood Pressure; Diet, Sodium-Restricted; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Receptors, Adrenergic, beta; Up-Regulation; Verapamil | 1993 |
A comparison of the antihypertensive effectiveness of a combination of moexipril or sustained-release verapamil with low-dose hydrochlorothiazide.
Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Delayed-Action Preparations; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines; Verapamil | 1996 |
Comparison of different fixed antihypertensive combination drugs: a double-blind, placebo-controlled parallel group study.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Drug Tolerance; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Lisinopril; Male; Middle Aged; Safety; Verapamil | 1997 |
The treatment of severe hypertension with trandolapril, verapamil, and hydrochlorothiazide. Trandolapril/Verapamil Multicenter Study Group.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Safety; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Treatment Outcome; Verapamil | 1997 |
Treatment of diastolic dysfunction in hypertensive patients without left ventricular hypertrophy.
Topics: Adult; Aged; Amiloride; Anti-Arrhythmia Agents; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Echocardiography, Doppler; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ventricular Dysfunction; Verapamil | 1998 |
Rationale and design for the Controlled ONset Verapamil INvestigation of Cardiovascular Endpoints (CONVINCE) Trial.
Topics: Aged; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Cerebrovascular Disorders; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Myocardial Infarction; Verapamil | 1998 |
Blood pressure and aortic elastic properties--verapamil SR/trandolapril compared to a metoprolol/hydrochlorothiazide combination therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta; Blood Pressure; Bradycardia; Calcium Channel Blockers; Cough; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Metoprolol; Middle Aged; Sodium Chloride Symporter Inhibitors; Verapamil | 1998 |
Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Confidence Intervals; Cross-Over Studies; Delayed-Action Preparations; Drug Combinations; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Lipoproteins; Male; Middle Aged; Treatment Outcome; Vasodilator Agents; Verapamil | 2000 |
Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers; Diastole; Diuretics; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine; Practice Guidelines as Topic; Proportional Hazards Models; Sodium Chloride Symporter Inhibitors; South Africa; Time Factors; Treatment Outcome; Vasodilator Agents; Verapamil | 2001 |
Effects of drug therapy on cardiac arrhythmias and ischemia in hypertensives with LVH.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Electrocardiography, Ambulatory; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome; Verapamil | 2001 |
Effect of two antihypertensive combinations on metabolic control in type-2 diabetic hypertensive patients with albuminuria: a randomised, double-blind study.
Topics: Aged; Albuminuria; Analysis of Variance; Antihypertensive Agents; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Multivariate Analysis; Probability; Prospective Studies; Spain; Treatment Outcome; Verapamil | 2001 |
Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial.
Topics: Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diastole; Diuretics; Echocardiography; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Methyldopa; Middle Aged; Nifedipine; Patient Compliance; Regression Analysis; South Africa; Systole; Verapamil | 2002 |
[Effect of antihypertensive combinations on arterial pressure, albuminuria, and glycemic control in patients with type II diabetic nephropathy: a randomized study].
Topics: Aged; Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Indoles; Lipids; Losartan; Male; Middle Aged; Prospective Studies; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Treatment Outcome; Vasodilator Agents; Verapamil | 2002 |
A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Treatment Outcome; Verapamil | 2003 |
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Channel Blockers; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Female; Follow-Up Studies; Hispanic or Latino; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertrophy, Left Ventricular; Indoles; Ischemic Attack, Transient; Male; Myocardial Revascularization; Residence Characteristics; Risk Factors; Stroke; Systole; Verapamil | 2006 |
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.
Topics: Adult; Aged; Antihypertensive Agents; Appetite Depressants; Blood Pressure; Body Weight; Cyclobutanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Metoprolol; Middle Aged; Obesity; Prospective Studies; Ramipril; Treatment Outcome; Verapamil | 2007 |
Reversal of diuretic-associated impaired glucose tolerance and new-onset diabetes: results of the STAR-LET study.
Topics: Analysis of Variance; Chi-Square Distribution; Diabetes Mellitus; Diuretics; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Indoles; Insulin Resistance; Losartan; Male; Metabolic Syndrome; Middle Aged; Renin-Angiotensin System; Verapamil | 2008 |
Dual therapy in hypertensive patients with coronary artery disease: the role of calcium channel blockers and beta-blockers.
Topics: Adrenergic beta-Antagonists; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; Verapamil | 2007 |
Comparing marginal structural models to standard methods for estimating treatment effects of antihypertensive combination therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Confounding Factors, Epidemiologic; Coronary Artery Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Models, Structural; Proportional Hazards Models; Risk Factors; Treatment Outcome; Verapamil | 2012 |
Association of KCNJ1 variation with change in fasting glucose and new onset diabetes during HCTZ treatment.
Topics: Aged; Antihypertensive Agents; Atenolol; Diabetes Mellitus; Fasting; Female; Glucose; Haplotypes; Humans; Hydrochlorothiazide; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Potassium Channels, Inwardly Rectifying; Prospective Studies; Verapamil | 2013 |
Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aldehyde Dehydrogenase 1 Family; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Drug Combinations; Drug Resistance; Female; Florida; Genome-Wide Association Study; Georgia; Humans; Hydrochlorothiazide; Hypertension; Indoles; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pharmacogenetics; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Prospective Studies; Retinal Dehydrogenase; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; Vasodilator Agents; Verapamil; Young Adult | 2017 |
50 other study(ies) available for hydrochlorothiazide and verapamil
Article | Year |
---|---|
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
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Topics: Animals; Catalysis; Catalytic Domain; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Kinetics; Lysine; Mice; Microsomes, Liver; Models, Molecular; Molecular Structure; Protein Conformation; Protein Glutamine gamma Glutamyltransferase 2; Pyridazines; Structure-Activity Relationship; Tissue Distribution; Transglutaminases | 2018 |
General activity in baboons measured with a computerized, lightweight piezoelectric motion sensor: effects of drugs.
Topics: Animals; Cocaine; Dextroamphetamine; Dronabinol; Hydrochlorothiazide; Male; Motor Activity; Papio; Psychology, Experimental; Verapamil | 1992 |
Chronic hydrochlorothiazide and verapamil effects on motor activity in hypertensive baboons.
Topics: Animals; Blood Pressure; Drug Interactions; Hydrochlorothiazide; Hypertension; Male; Motor Activity; Papio; Verapamil | 1992 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Infusions, Intravenous; Male; Methyldopa; Middle Aged; Nifedipine; Ventricular Function, Left; Verapamil | 1991 |
[Combination therapy in chronic heart failure. Hemodynamic effects with a calcium antagonist-diuretic combination].
Topics: Adult; Aged; Chronic Disease; Drug Combinations; Heart Failure; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension, Pulmonary; Middle Aged; Triamterene; Verapamil | 1991 |
Behavioral effects of chronic, orally administered diuretic and verapamil in baboons.
Topics: Animals; Behavior, Animal; Blood Pressure; Color Perception; Conditioning, Operant; Desoxycorticosterone; Discrimination, Psychological; Diuretics; Electrolytes; Hydrochlorothiazide; Male; Papio; Psychomotor Performance; Reaction Time; Triamterene; Verapamil | 1991 |
Development of hypertension and life span in stroke-prone spontaneously hypertensive rats during oral long-term treatment with various antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Dihydralazine; Heart; Hydrochlorothiazide; Hypertension; Life Expectancy; Male; Organ Size; Propranolol; Rats; Rats, Inbred SHR; Verapamil | 1989 |
Erythrocyte cation transport in obesity, hypertension, and during antihypertensive drug therapy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Cations; Erythrocytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity; Potassium Channels; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Verapamil | 1989 |
Hydrochlorothiazide is not additive to verapamil in treating essential hypertension.
Topics: Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Renin; Verapamil | 1989 |
Diuretics and calcium antagonists in hypertension.
Topics: Bendroflumethiazide; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Sodium Chloride Symporter Inhibitors; Verapamil | 1988 |
Effect of calcium-entry blockers on the diuretic response to hydrochlorothiazide in the rat.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Diuresis; Female; Hydrochlorothiazide; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1988 |
Comparison of sustained release verapamil and hydrochlorothiazide in hypertension--effect on blood pressure and metabolic variables.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Cholesterol; Delayed-Action Preparations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Verapamil | 1987 |
Efficacy of verapamil--hydrochlorothiazide-spironolactone therapy in hypertensive black patients.
Topics: Adult; Aged; Black People; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Spironolactone; Verapamil | 1987 |
[Treatment of essential hypertension (hypertensive disease) with verapamil and hydrochlorothiazide].
Topics: Adult; Blood Pressure; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Verapamil | 1985 |
[Simultaneous poisoning with medigoxin, verapamil, insulin, medazepam, diazepam, butamirate, triamterene and hydrochlorothiazide].
Topics: Antitussive Agents; Diazepam; Humans; Hydrochlorothiazide; Insulin; Male; Medazepam; Medigoxin; Middle Aged; Phenylbutyrates; Poisoning; Suicide, Attempted; Triamterene; Verapamil | 1983 |
Metabolic parameters after changing from hydrochlorothiazide to verapamil treatment in hypertension.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; C-Peptide; Creatinine; Fatty Acids, Nonesterified; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Insulin; Lipids; Male; Middle Aged; Uric Acid; Verapamil; Water-Electrolyte Balance | 1984 |
[Oral verapamil combined with a diuretic in the treatment of slight and moderate arterial hypertension].
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Verapamil | 1982 |
[Treatment of hypertension with a fixed calcium antagonist-diuretic combination. Observations from treatment of 5,595 patients].
Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Product Surveillance, Postmarketing; Triamterene; Verapamil | 1995 |
Stability of labetalol hydrochloride, metoprolol tartrate, verapamil hydrochloride, and spironolactone with hydrochlorothiazide in extemporaneously compounded oral liquids.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diuretics; Dosage Forms; Drug Compounding; Drug Stability; Humans; Hydrochlorothiazide; Labetalol; Metoprolol; Sodium Chloride Symporter Inhibitors; Spironolactone; Suspensions; Verapamil | 1996 |
Diphenylamine-2-carboxylic acid (DPC), Usually an inhibitor of Cl- and non-selective cation channels, inhibits Cl-/HCO3- exchange and opens Cl- and cation conductances in rabbit gallbladder epithelium.
Topics: Animals; Anions; Apamin; Calcium Channel Blockers; Cations; Chloride Channels; Chloride-Bicarbonate Antiporters; Chlorides; Diuretics; Epithelial Cells; Gallbladder; Hydrochlorothiazide; Ion Channel Gating; Male; Membrane Potentials; ortho-Aminobenzoates; Patch-Clamp Techniques; Rabbits; Sodium Chloride Symporter Inhibitors; Verapamil | 2001 |
The effect of the fast of Ramadan on ambulatory blood pressure in treated hypertensives.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Fasting; Female; Humans; Hydrochlorothiazide; Hypertension; Islam; Male; Middle Aged; Nifedipine; Religion and Medicine; Sleep; Verapamil | 2001 |
Calcium antagonist strategies for coronary artery disease.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Diastole; Humans; Hydrochlorothiazide; Indoles; Randomized Controlled Trials as Topic; Systole; Verapamil | 2004 |
[Lethal polypharmacy in a patient with arterial hypertension].
Topics: Aged; Aged, 80 and over; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cerebral Infarction; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Indoles; Male; Polypharmacy; Sodium Chloride Symporter Inhibitors; Timolol; Tomography, X-Ray Computed; Verapamil | 2004 |
pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Chromatography, High Pressure Liquid; Furosemide; Hydrochlorothiazide; Hydrogen-Ion Concentration; Ileum; Intestinal Absorption; Jejunum; Membranes, Artificial; Perfusion; Permeability; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Verapamil | 2005 |
A drug dose model for predicting clinical outcomes in hypertensive coronary disease patients.
Topics: Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chi-Square Distribution; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Predictive Value of Tests; Proportional Hazards Models; Randomized Controlled Trials as Topic; Treatment Outcome; Verapamil | 2005 |
The effect of Ramadan fasting on ambulatory blood pressure in hypertensive patients using combination drug therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Drug Therapy, Combination; Fasting; Female; Humans; Hydrochlorothiazide; Hypertension; Islam; Male; Middle Aged; Nifedipine; Religion and Medicine; Verapamil | 2008 |
Predicting stroke risk in hypertensive patients with coronary artery disease: a report from the INVEST.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Black People; Coronary Artery Disease; Databases, Factual; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Risk Factors; Stroke; United States; Verapamil | 2008 |
INVEST revisited: review of findings from the International Verapamil SR-Trandolapril Study.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Coronary Artery Disease; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Randomized Controlled Trials as Topic; Verapamil | 2009 |
[Effect of major components of maijunan tablets on the transport of hydrochlorothiazide in Caco-2 cell monolayer model].
Topics: Absorption; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Drugs, Chinese Herbal; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Indole Alkaloids; Isoflavones; Oxindoles; Plants, Medicinal; Time Factors; Vasodilator Agents; Verapamil | 2010 |
An HPLC-UV method for the measurement of permeability of marker drugs in the Caco-2 cell assay.
Topics: Acyclovir; Caco-2 Cells; Carbamazepine; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Intestinal Mucosa; Pharmaceutical Preparations; Propranolol; Ultraviolet Rays; Verapamil; Vinblastine | 2011 |
G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Female; G-Protein-Coupled Receptor Kinase 4; Genotype; Haplotypes; Humans; Hydrochlorothiazide; Hypertension; Male; Pharmacogenetics; Polymorphism, Single Nucleotide; Treatment Outcome; Verapamil | 2012 |
Association of 1-Year Blood Pressure Variability With Long-term Mortality Among Adults With Coronary Artery Disease: A Post Hoc Analysis of a Randomized Clinical Trial.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Coronary Artery Disease; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Mortality; Proportional Hazards Models; Randomized Controlled Trials as Topic; Sex Factors; Verapamil | 2021 |