hydrochlorothiazide has been researched along with valsartan in 201 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (3.48) | 18.2507 |
| 2000's | 90 (44.78) | 29.6817 |
| 2010's | 93 (46.27) | 24.3611 |
| 2020's | 11 (5.47) | 2.80 |
| Authors | Studies |
|---|---|
| Faller, B; Wohnsland, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Avery, C; Benz, J; Chiang, YT; Gatlin, M; Henry, D; Oshrain, C | 1 |
| Bodin, F; Faust, G; Freytag, F; Hegner, G; Meilenbrock, S; Sullivan, J | 1 |
| Davis, S; Navarrete, AE; Webb, RL | 1 |
| Benz, JR; Black, HR; Fitzsimmons, S; Graff, A; Reed, A; Shi, Y | 1 |
| Thürmann, PA | 1 |
| Langtry, HD; McClellan, KJ | 1 |
| Gottdiener, JS | 1 |
| Lee, TH | 1 |
| Altinay, S; Göğer, NG; Ozkan, SA; Satana, E; Sentürk, Z | 1 |
| Bedigian, MP; Neutel, JM; Smith, DH; Weir, MR | 1 |
| Bertocchi, F; Bonaduce, D; Carretta, R; Condorelli, M; Fogari, R; Malacco, E; Mann, J; Palatini, P | 1 |
| Asmar, R; Ghobrial, H; Herpin, D; Mallion, JM; Poncelet, P; Vaïsse, B; Vaur, L | 1 |
| Aschwanden, R; Ferber, P; Sadecky, L; Waeber, B | 1 |
| Adam, SA; Handrock, R; Kolloch, R; Schmidt, A; Weidinger, G | 1 |
| Bertocchi, F; Carretta, R; Di, SS; Dorigatti, F; Malacco, E; Mann, J; Palatini, P | 1 |
| Faulds, DM; Wellington, K | 1 |
| Jacobi, J; John, S; Klingbeil, AU; Schmieder, RE; Schneider, MP; Weidinger, G | 1 |
| Handrock, R; Jacobi, J; John, S; Klingbeil, AU; Schmieder, RE; Schneider, MP | 1 |
| Mengden, T; Vetter, H; Weisser, B | 1 |
| Carretta, R; Fagan, T; Mallion, JM; Martinez, JF; Oddou, P; Teitelbaum, I; Trenkwalder, P; Tykarski, A | 1 |
| Della Chiesa, A; Hess, OM; Meier, B; Pfiffner, D | 1 |
| Preobrazhenskiĭ, DV; Sidorenko, BA; Stetsenko, TM; Tarykina, EV; Tsurko, VV | 1 |
| Agelink, MW; Passenberg, P; Ullrich, H | 1 |
| Borgnino, C; Capuano, V; Malacco, E; Palatini, P; Spagnuolo, V; Varì, N | 1 |
| Franco, RJ; Goldflus, S; McQuitty, M; Oigman, W | 1 |
| Chrysant, SG | 2 |
| Ambrosia, GB; Caiazza, A; Malacco, E; Mugellini, A; Palatini, P; Santonastaso, M; Spagnuolo, V | 1 |
| Brunner, HR; Ekman, S; Hansson, L; Hua, T; Julius, S; Kjeldsen, SE; Laragh, J; McInnes, GT; Mitchell, L; Plat, F; Schork, A; Smith, B; Weber, M; Zanchetti, A | 1 |
| Brunel, P; Denolle, T; Fiquet, B; Girerd, X; Herpin, D; Moulin, B; Yau, C | 1 |
| Brandão, AA; Heintz, D; Kandra, A; Khder, Y; Ruilope, LM; Santonastaso, M; Stolt, P | 1 |
| Bönner, G; Heintz, D; Kandra, A; Khder, Y; Malacco, E; Ruilope, LM | 1 |
| Daley, W; Ferdinand, KC; Flack, JM; Jamerson, KA; Weir, MR; Zelenkofske, S | 1 |
| Assouline, L; Hebert, D; Khder, Y; Lacourcière, Y; Poirier, L; Rehel, B; Stolt, P | 1 |
| Boschmann, M; Engeli, S; Jordan, J; Kreuzberg, U; Luft, FC; Sharma, AM; Weidinger, G | 1 |
| Asmar, R; Bobrie, G; Delonca, J; Giacomino, A; Moulin, C; Postel-Vinay, N | 1 |
| Abts, M; Claus, V; Lataster, M | 1 |
| Danielson, E; Glynn, RJ; Ridker, PM; Rifai, N | 1 |
| Mittal, BV; Pendse, S; Rennke, HG; Singh, AK | 1 |
| Davidai, G; Koval, SE; Murwin, D; Neutel, JM; Punzi, HA; White, WB | 1 |
| Ruilope, LM; Zanchetti, A | 1 |
| Wagstaff, AJ | 1 |
| Bizot, MN; Denouel, J; Dieterich, HA; Dole, WP; Kemp, C; Vaidyanathan, S; Valencia, J; Yeh, CM; Zhao, C | 1 |
| Kobalava, ZhD; Villeval'de, SV | 1 |
| Aldigier, JC; Azizi, M; Chiang, Y; Januszewicz, A; Pool, JL; Satlin, A; Schmieder, RE; Zidek, W | 1 |
| Crikelair, N; Glazer, R; Kuturu, V; Levy, D; Rocha, R; Weir, MR | 1 |
| Gu, J; Jiang, Y; Li, H; Tang, Y; Wang, J; Wang, Y; Zhao, L | 1 |
| Alvarado, R; Glazer, R; Graff, A; Huang, J; Pool, JL; Weinberger, M | 1 |
| Chiang, YT; Fomina, I; Gamboa, R; Glazes, R; Kaczor, J; Kargiannis, S; Poldermans, D; Wernsing, M; Yen, J | 1 |
| Crikelair, N; Glazer, R; Levy, D; Meng, X; Rocha, R; Weir, MR | 1 |
| Müller, U; Scholze, J | 1 |
| Abts, M; Kastrati, D; Schühlen, H | 1 |
| Ashiya, M; Smith, RE | 1 |
| Davidson, J; Koval, S; Lacourcière, Y; Sharma, AM | 1 |
| Handrock, R; Hilsmann, U; Klebs, S; Neumann, G; Schweizer, J | 1 |
| Conen, D; Everett, BM; Glynn, RJ; Ridker, PM | 1 |
| Sun, NL; Wang, HY; Zhu, JR | 1 |
| Chrysant, SG; Davidai, G; Guthrie, R; Koval, SE; Murwin, D; White, WB | 1 |
| Chrysant, SG; Dattani, D; Hoppe, UC; Hsu, H; Murray, AV; Patel, S; Zhang, J | 1 |
| Allemann, Y; Barbier, M; Ferber, P; Fraile, B; Izzo, JL; Lambert, M | 1 |
| Botha, J; DeAngelis, L; Ferber, P; Kandra, A; Karalliedde, J; Mirenda, V; Smith, A; Viberti, G | 1 |
| Danielson, E; Everett, BM; Glynn, RJ; Ridker, PM | 1 |
| Curnew, GP; Leclerc, JM; Rehel, B; Tardif, JC | 1 |
| Calhoun, DA; Purkayastha, D; Samuel, R; Taylor, AA; White, WB; Zappe, DH | 1 |
| Calhoun, DA; Coenen, PD; Glazer, RD; Grosso, A; Pettyjohn, FS; Zhao, Y | 1 |
| Mourad, JJ; Waeber, B | 1 |
| Crikelair, N; Nash, DT; Zappe, D | 1 |
| Baumgart, P; Ferber, P; Le Breton, S; Reimund, B; Tuomilehto, J; Tykarski, A | 1 |
| Sun, NL; Tu, YM; Zhao, Y; Zhu, JR | 1 |
| Brixner, DI; Jackson, KC; Keskinaslan, A; Nelson, RE; Sheng, X | 2 |
| Crikelair, N; Lastra, G; Levy, DG; Rocha, R; Seifu, Y; Sowers, JR | 1 |
| Deedwania, PC; Fonseca, VA; Haffner, SM; Hsueh, WA; Keeling, L; Sica, DA; Sowers, JR; Zappe, DH | 1 |
| Araki, SI; Haneda, M; Isshiki, K; Kanasaki, M; Kashiwagi, A; Koya, D; Kume, S; Sakaguchi, M; Sugiomoto, T; Uzu, T; Yokomaku, Y | 1 |
| Düsing, R; Handrock, R; Klebs, S; Tousset, E; Vrijens, B | 1 |
| Davidai, G; Schumacher, H; White, WB | 1 |
| Black, HR; Lacourcière, Y; Purkayastha, D; Samuel, R; Wright, JT; Zappe, D | 2 |
| Black, HR | 1 |
| Calhoun, DA; Chiang, YT; Glazer, RD; Lacourcière, Y | 1 |
| Barranco, E; Geiger, H; Gorostidi, M; Taylor, A; Xiang, Z; Zhang, J; Zhang, X | 1 |
| Kondrack, R; Mohiuddin, S | 1 |
| Andraus, MH; Azevedo, CP; Borges, BC; Borges, NC; Moreira, RF; Moreno, RA; Salvadori, MC | 1 |
| Crikelair, N; Glazer, R; Levy, D; Pool, JL | 1 |
| Ferber, P; Papst, CC; Zappe, D | 1 |
| Bailey, J; Black, HR; Samuel, R; Zappe, D | 1 |
| Deeks, ED | 1 |
| Lacourcière, Y; Poirier, L; Samuel, R | 1 |
| Calhoun, DA; Jamerson, KA; Palmer, BF; Purkayastha, D; Samuel, R; Zappe, DH | 1 |
| Calhoun, DA; Crikelair, NA; Glazer, RD; Yen, J | 1 |
| Burnier, M; Coltamai, L; Maillard, M; Simon, A; Vogt, B | 1 |
| Chiang, YT; Crikelair, NA; Glazer, RD; Weinberger, MH | 1 |
| Cagnoni, F; D'Ospina, A; Demichele, E; Destro, M; Peros, E; Preti, P; Ricci, AR; Zaninelli, A | 1 |
| Ekman, M; Fragoulakis, V; Maniadakis, N; Papagiannopoulou, V; Yfantopoulos, J | 1 |
| Deedwania, PC; Egan, BM; Jialal, I; Ofili, EO; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH | 1 |
| Lin, S; Shi, H; Zheng, Z | 1 |
| Abraham, I; Brié, H; Chen, HC; Fidel, GE; Hermans, C; Ko, ML; Lee, CS; MacDonald, K; Reel, S; Van der Niepen, P; Vancayzeele, S | 1 |
| Ayalasomayajula, S; Bhad, P; Jarugula, V; Karan, R; Leon, S; Riviere, GJ; Sunkara, G | 1 |
| Crikelair, N; Destro, M; Glazer, R; Yen, J | 1 |
| Chrysant, SG; Dattani, D; Hoppe, UC; Murray, AV; Patel, S; Ritter, S; Zhang, J | 1 |
| Barrios, V; Escobar, C | 1 |
| Asmar, R; Oparil, S | 1 |
| Akhtari, S; Andalib, A; Curnew, G; Leclerc, JM; Rigal, R; Tardif, JC; Vaillancourt, M | 1 |
| Calhoun, DA; Crikelair, N; Glazer, RD; Lacourcière, Y; Yen, J | 1 |
| Bouabidi, A; Bouklouze, A; Bourichi, H; El Guezzar, M; El Karbane, M; Hubert, P; Rozet, E; Talbi, M; Ziemons, E | 1 |
| Lakshmi, KS; Lakshmi, S | 1 |
| Dongre, N; Lai, WT; Park, JE; Wang, J | 1 |
| Aderibigbe, A; Anisiuba, BC; Ba, SA; Boombhi, HJ; Ijoma, CK; Kamdem, MK; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, AN; Omotoso, BA; Richart, T; Staessen, JA; Thijs, L; Ulasi, II | 1 |
| Circelli, M; Cremonesi, G; Fogari, R; Mugellini, A | 1 |
| Bains, J; Smith, WB | 1 |
| Cushman, WC; Duprez, DA; Izzo, JL; Purkayastha, D; Samuel, R; Weintraub, HS; Zappe, D | 2 |
| Duprez, D; Ferdinand, KC; Purkayastha, D; Samuel, R; Wright, RF | 1 |
| Ayala, DE; Fernández, JR; Fontao, MJ; Hermida, RC; Mojón, A | 1 |
| Abraham, I; Aerts, A; Brié, H; Coen, N; Hermans, C; Lee, C; Lins, R; Macdonald, K; Mecum, N; Shen, YM; Vancayzeele, S | 1 |
| Egan, BM; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH | 1 |
| Inoue, A; Kuwano, T; Mitsutake, R; Miura, S; Morii, J; Saku, K; Shiga, Y; Uehara, Y | 1 |
| Huang, Y; Jiang, J; Li, Y; Liu, H; Tian, L; Xie, S; Xu, L | 1 |
| Christogiannis, LG; Elisaf, MS; Kostapanos, MS; Milionis, HJ; Tellis, CC; Tselepis, AD | 1 |
| Duprez, D; Ferdinand, K; Purkayastha, D; Samuel, R; Wright, R | 1 |
| Ofili, EO; Purkayastha, D; Samuel, R; Sowers, JR; Zappe, DH | 1 |
| Cushman, WC; Duprez, DA; Izzo, JL; Purkayastha, D; Samuel, R; Weintraub, HS; Zappe, DH | 1 |
| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A | 1 |
| Pancholi, SS; Sharma, RN | 1 |
| Sun, CX; Tao, CW; Wu, ZB; Yu, QG; Zhang, Y | 1 |
| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Barrios, V; de la Sierra, A | 1 |
| Deedwania, PC; Egan, BM; Purkayastha, D; Samuel, R; Sowers, JR; Zappe, DH | 1 |
| Chen, JF; Hung, YJ; Lee, IT; Lee, WJ; Sheu, WH; Wang, CY | 2 |
| Lacourcière, Y | 1 |
| Brunner, HR; Hua, TA; Jia, Y; Julius, S; Kjeldsen, SE; Mancia, G; McInnes, GT; Schork, A; Weber, MA; Zanchetti, A; Zappe, DH | 1 |
| Al Balushi, KA; Al-Zakwani, I; Habib, JQ | 1 |
| Kothari, C; Mehta, P; Sharma, M; Sherikar, O | 1 |
| Freytag, S; Hagendorff, A; Klebs, S; Müller, A | 1 |
| Aksenova, AV; Chazova, IE; Elfimova, EM; Galitsin, PV; Litvin, AY; Rogoza, AN; Sukmarova, ZN | 1 |
| Calhoun, DA; Crikelair, N; Glazer, RD; Jia, Y; Lacourcière, Y | 1 |
| Darwish, HW; El-Zeany, BA; Hassan, SA; Salem, MY | 2 |
| Hedaya, MA; Helmy, SA | 1 |
| Anisiuba, BC; Ba, SA; Boombhi, HJ; Ezeala-Adikaibe, B; Ijoma, CK; Jacobs, L; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'Buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, A; Omotoso, BA; Osakwe, CE; Staessen, JA; Thijs, L; Ulasi, II | 1 |
| Gnudi, L; Hill, B; Karalliedde, J; Maltese, G; Viberti, G | 1 |
| Basile, G; Epifanio, A; Mandraffino, R; Trifirò, G | 1 |
| Chen, XY; Shao, D; Zhan, Y; Zhang, YF; Zhong, DF | 1 |
| Ding, HY; Guo, W; Li, GR; Li, XX; Yu, YG; Zhi, L | 1 |
| Kobalava, ZhD; Kotovskaia, IuV; Kravtsova, OA; Lobzhanidze, TV | 1 |
| Cheng, KK; Etemadi, A; Hemming, K; Jaafari, E; Khoshnia, M; Majed, M; Malekzadeh, F; Malekzadeh, R; Marjani, H; Marshall, T; Merat, S; Mohammadifard, N; Naemi, M; Nateghi, A; Navabakhsh, B; Ostovaneh, MR; Pourshams, A; Poustchi, H; Sadeghi, M; Sarrafzadegan, N; Thomas, GN | 1 |
| Crikelair, N; Kandra, A; Palatini, P; Zappe, DH | 1 |
| Finck, A; Giles, TD; Li, H; Neutel, JM; Punzi, H; Weiss, RJ | 1 |
| Hegazy, MA; Lotfy, HM; Mohamed, EH; Mowaka, S | 2 |
| Assaad-Khalil, SH; Cho, B; DiTommaso, S; Kitchlew, AR; Najem, R; Shete, A; Sison, J; Ueng, KC | 1 |
| Coufal, P; Janečková, L; Jedlička, A; Vojta, J | 1 |
| Ebeid, W; El-Bagary, R; Elkady, E; Elzahr, A; Patonay, G; Salim, M | 1 |
| Anraku, Y; Inami, S; Inoue, T; Kato, T; Kikegawa, Y; Nakamoto, A; Node, K; Suzuki, A; Toyoda, S; Tsukada, K | 1 |
| Hemming, K; Jafari, E; Khoshnia, M; Malekzadeh, R; Marshall, T; Merat, S; Nateghi, A; Poustchi, H; Radmard, AR; Shiravi Khuzani, A | 1 |
| Chen, W; Kahler, KH; Machnicki, G; Ong, SH; Wei, ZJ | 1 |
| Greeley, M; Hsiao, HL; Langenickel, TH; Pal, P; Rajman, I; Rebello, S; Roberts, J; Sunkara, G; Zhou, W | 1 |
| Izzo, JL; Jia, Y; Zappe, DH | 1 |
| Accetto, R; Barbič-Žagar, B; Chazova, IY; Sirenko, Y; Vincelj, J; Widimsky, J | 1 |
| Chen, X; Gao, X; Lu, G; Luo, C; Luo, J; Peng, L; Zuo, Z | 1 |
| Agha, H; Arafat, T; Idkaidek, N | 1 |
| Akkermans, R; Biermans, M; Deinum, J; Lenders, JWM; van der Wel, MC; van Weel, C | 1 |
| Accetto, R; Barbic Zagar, B; Sirenko, Y; Vincelj, J; Widimsky, J; Yevgenyevna, IC | 1 |
| Abe, J; Fukuda, A; Hasegawa, S; Hatahira, H; Ishiguro, M; Kanoh, H; Kinosada, Y; Motooka, Y; Naganuma, M; Nakamura, M; Nakao, S; Sasaoka, S; Seishima, M; Ueda, N | 1 |
| Fujiwara, T; Kanegae, H; Kario, K; Tomitani, N | 1 |
| Dai, M; Qian, D; Tao, H; Zhang, C | 1 |
| Ahn, T; Ahn, Y; Cha, KS; Chang, K; Han, KR; Hyon, MS; Jo, SH; Kim, DI; Kim, SW; Kim, W; Kim, Y; Kwan, J; Lee, NH; Lee, SY; Lim, SW; Rhee, MY; Shim, CY | 1 |
| Břicháč, J; Douša, M; Gibala, P; Kalášek, S; Kalužíková, A; Štefko, M; Tkadlecová, M | 1 |
| Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M | 1 |
| Hebibovic, S; Jatic, Z; Rustempasic, E; Skopljak, A; Sukalo, A; Valjevac, A | 1 |
| Boffetta, P; Brennan, P; Cheng, KK; Etemadi, A; Fazel, A; Gharavi, A; Hemming, K; Kamangar, F; Khoshnia, M; Majed, M; Malekzadeh, F; Malekzadeh, R; Marshall, T; Merat, S; Mohammadifard, N; Naemi-Tabiei, M; Nalini, M; Nateghi, A; Navabakhsh, B; Ostovaneh, MR; Pourshams, A; Poustchi, H; Roshandel, G; Sadeghi, M; Sarrafzadegan, N; Thomas, N | 1 |
| Bianco, HT; Ferreira, CES; Figueiredo Neto, AM; Fonseca, FAH; França, CN; Izar, MCO; Kato, JT; Massunaga, ND; Póvoa, RMS | 1 |
| Abdelsalam, RA; Haddad, GM; Marghany, KA | 1 |
| Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM | 1 |
| Abdul, A; Pathan, MAAK; Raut, S; Shaikh, JSA | 1 |
| Bots, ML; Groenland, EH; Spiering, W; van der Elst, KCM; van Kleef, MEAM; Visseren, FLJ | 1 |
| Abousalih, FZ; Azougagh, M; Benchekroun, YH; Bennani, I; Bouatia, M; El Karbane, M; Saffaj, T | 1 |
| Fujiwara, T; Hoshide, S; Kanegae, H; Kario, K; Tomitani, N | 1 |
| Cox, E; Ishigami, J; Miller, ER; Moran, AE; Pfister, M; Qin, L; Zhang, N | 1 |
| Abdelkawy, M; El-Hanboushy, S; Fayez, YM; Lotfy, HM; Marzouk, HM | 1 |
| Liang, H; Tang, T; Xie, M | 1 |
| Tchernev, G | 1 |
22 review(s) available for hydrochlorothiazide and valsartan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Valsartan/hydrochlorothiazide.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 1999 |
Valsartan/hydrochlorothiazide: a review of its pharmacology, therapeutic efficacy and place in the management of hypertension.
Topics: Antihypertensive Agents; Databases, Bibliographic; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
[Angiotensin I receptor antagonist losartan. Part II. Effects in arterial hypertension and diabetic nephropathy].
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Meta-Analysis as Topic; Placebos; Prognosis; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2003 |
Fixed combination therapy of hypertension: focus on valsartan/hydrochlorothiazide combination (Diovan/HCT).
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
Valsartan/hydrochlorothiazide: a review of its use in the management of hypertension.
Topics: Antihypertensive Agents; Drug Interactions; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
[Combination therapy in contemporary strategy of treatment of arterial hypertension. Review of data on efficacy and safety of fixed combination valsartan and hydrochlorothiazide].
Topics: Angiotensin II Type 1 Receptor Blockers; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2006 |
Evaluation of the dose response with valsartan and valsartan/hydrochlorothiazide in patients with essential hypertension.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2007 |
Time to achieve blood-pressure goal: influence of dose of valsartan monotherapy and valsartan and hydrochlorothiazide combination therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2007 |
Valsartan/hydrochlorothiazide: pharmacology and clinical efficacy.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
Valsartan: more than a decade of experience.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Meta-Analysis as Topic; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2009 |
Valsartan plus hydrochlorothiazide for first-line therapy in hypertension.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Patient Compliance; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2009 |
A systematic review and meta-analysis of telmisartan versus valsartan in the management of essential hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Confidence Intervals; Diastole; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Renin-Angiotensin System; Risk; Systole; Telmisartan; Tetrazoles; Valine; Valsartan | 2010 |
Valsartan-amlodipine-hydrochlorothiazide: the definitive fixed combination?
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Medication Adherence; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Combination delapril/manidipine as antihypertensive therapy in high-risk patients.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Dihydropyridines; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Irbesartan; Losartan; Nitrobenzenes; Obesity; Olmesartan Medoxomil; Piperazines; Ramipril; Tetrazoles; Valine; Valsartan | 2011 |
Valsartan plus hydrochlorothiazide: a review of its use since its introduction.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Costs; Drug Synergism; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Renal Insufficiency; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left | 2011 |
Single-pill triple-combination therapy: an alternative to multiple-drug treatment of hypertension.
Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Design; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tetrazoles; Valine; Valsartan | 2011 |
Blood pressure control with angiotensin receptor blocker-based three-drug combinations: key trials.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2012 |
Telmisartan or valsartan alone or in combination with hydrochlorothiazide: a review.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
Plasma Trough Concentrations of Antihypertensive Drugs for the Assessment of Treatment Adherence: A Meta-Analysis.
Topics: Amlodipine; Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Treatment Adherence and Compliance; Valsartan | 2021 |
Dyskalemia risk associated with fixed-dose anti-hypertensive medication combinations.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Hypokalemia; Tetrazoles; Valsartan | 2022 |
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan | 2023 |
109 trial(s) available for hydrochlorothiazide and valsartan
| Article | Year |
|---|---|
Valsartan, a new angiotensin II receptor antagonist: a double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cough; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 1997 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared to hydrochlorothiazide.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1997 |
Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with monotherapy.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Angiotensin II antagonism and the heart: valsartan in left ventricular hypertrophy.
Topics: Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertrophy, Left Ventricular; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 1999 |
Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Diuretics; Drug Interactions; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Organ Size; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Research Design; Tetrazoles; Valine; Valsartan | 1999 |
Valsartan alone or with a diuretic or ACE inhibitor as treatment for African American hypertensives: relation to salt intake.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Black People; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pilot Projects; Prospective Studies; Sodium Chloride Symporter Inhibitors; Sodium, Dietary; Tetrazoles; Valine; Valsartan | 2001 |
A multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination versus amlodipine in patients with mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2001 |
[Antihypertensive effect of valsartan 80 mg and hydrochlorothiazide 12.5 mg evaluated by ambulatory blood pressure monitoring].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2001 |
Combination of hydrochlorothiazide or benazepril with valsartan in hypertensive patients unresponsive to valsartan alone.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Diuretics; Drug Combinations; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2001 |
Antihypertensive effects of valsartan/hydrochlorothiazide combination in essential hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Male; Middle Aged; Tetrazoles; Therapeutic Equivalency; Treatment Outcome; Valine; Valsartan | 2001 |
Trough:peak ratio and smoothness index in the evaluation of 24-h blood pressure control in hypertension: a comparative study between valsartan/hydrochlorothiazide combination and amlodipine.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Valine; Valsartan | 2002 |
AT1-receptor blockade improves augmentation index: a double-blind, randomized, controlled study.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Aorta; Blood Pressure; Diastole; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pulse; Radial Artery; Receptor, Angiotensin, Type 1; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Valine; Valsartan | 2002 |
Effect of AT1 receptor blockade on endothelial function in essential hypertension.
Topics: Acetylcholine; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Cohort Studies; Diuretics; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; omega-N-Methylarginine; Receptor, Angiotensin, Type 1; Regional Blood Flow; Rest; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2003 |
[Lowering of blood pressure, blood pressure amplitude and heart rate by treatment with valsartan or valsartan/hydrochlorothiazide. Results of an open observation study of 11,447 hypertensives].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Safety; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
Valsartan/hydrochlorothiazide is effective in hypertensive patients inadequately controlled by valsartan monotherapy.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
Sexual activity in hypertensive men.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Coitus; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Sexual Behavior; Sodium Chloride Symporter Inhibitors; Surveys and Questionnaires; Tetrazoles; Valine; Valsartan | 2003 |
A randomized, double-blind, active-controlled, parallel-group comparison of valsartan and amlodipine in the treatment of isolated systolic hypertension in elderly patients: the Val-Syst study.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Valine; Valsartan | 2003 |
Efficacy and tolerability of the combination valsartan/hydrochlorothiazide compared with amlodipine in a mild-to-moderately hypertensive Brazilian population.
Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brazil; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Racial Groups; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2003 |
Comparison of the effects on 24-h ambulatory blood pressure of valsartan and amlodipine, alone or in combination with a low-dose diuretic, in elderly patients with isolated systolic hypertension (Val-syst Study).
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2004 |
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Double-Blind Method; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
24-hour ambulatory blood-pressure effects of valsartan and hydrochlorothiazide combinations compared with amlodipine in hypertensive patients at increased cardiovascular risk: a VAST sub-study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other cardiovascular risk factors: the VAST study.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial Infarction; Obesity; Risk Factors; Tetrazoles; Valine; Valsartan | 2005 |
A noninferiority comparison of valsartan/hydrochlorothiazide combination versus amlodipine in black hypertensives.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Black People; Blood Pressure; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Antihypertensive efficacy and tolerability of two fixed-dose combinations of valsartan and hydrochlorothiazide compared with valsartan monotherapy in patients with stage 2 or 3 systolic hypertension: an 8-week, randomized, double-blind, parallel-group tri
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Valine; Valsartan | 2005 |
Hemodynamic and metabolic responses to valsartan and atenolol in obese hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Obesity; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2005 |
A home blood pressure monitoring study comparing the antihypertensive efficacy of two angiotensin II receptor antagonist fixed combinations.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Musculoskeletal Diseases; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; C-Reactive Protein; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Inflammation; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2006 |
Effects of the angiotensin II receptor blockers telmisartan vs valsartan in combination with hydrochlorothiazide 25 mg once daily for the treatment of hypertension.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Telmisartan; Tetrazoles; United States; Valine; Valsartan | 2006 |
Targeting hypertension with valsartan: Lessons learned from the Valsartan/HCTZ versus Amlodipine in stage II hypertensive patients (VASt) trial.
Topics: Amlodipine; C-Reactive Protein; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Interleukin-6; Lipoproteins, LDL; Tetrazoles; Tissue Plasminogen Activator; Valine; Valsartan | 2006 |
Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan.
Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Comparison of valsartan/hydrochlorothiazide combination therapy at doses up to 320/25 mg versus monotherapy: a double-blind, placebo-controlled study followed by long-term combination therapy in hypertensive adults.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Tolerability and blood pressure-lowering efficacy of the combination of amlodipine plus valsartan compared with lisinopril plus hydrochlorothiazide in adult patients with stage 2 hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
[Intensive blood pressure reduction in patients with increased cardiovascular risk with high-dose combination therapy of 160 mg valsartan plus 25 mg hydrochlorothiazide. Results of the MACHT II observational study].
Topics: Antihypertensive Agents; Death, Sudden, Cardiac; Drug Administration Schedule; Drug Therapy, Combination; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Assessment; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Telmisartan/hydrochlorothiazide versus valsartan/hydrochlorothiazide in obese hypertensive patients with type 2 diabetes: the SMOOTH study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus, Type 2; Diastole; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Obesity; Placebos; Single-Blind Method; Systole; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
Efficacy and safety of valsartan 160/HCTZ 25 mg in fixed combination in hypertensive patients not controlled by candesartan 32 mg plus HCTZ 25 mg in free combination.
Topics: Benzimidazoles; Biphenyl Compounds; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Tetrazoles; Valine; Valsartan | 2007 |
Effect of valsartan compared with valsartan/hydrochlorothiazide on plasma levels of cellular adhesion molecules: the Val-MARC trial.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Hydrochlorothiazide; Hypertension; Intercellular Adhesion Molecule-1; Male; Middle Aged; Tetrazoles; Valine; Valsartan; Vascular Cell Adhesion Molecule-1 | 2008 |
[Therapeutic efficacy of valsartan and valsartan/HCTZ in mild to moderate hypertensive patients].
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Effects of the angiotensin II receptor blockers telmisartan versus valsartan in combination with hydrochlorothiazide: a large, confirmatory trial.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2008 |
Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: the Exforge in Failure after Single Therapy (EX-FAST) study.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Retreatment; Tetrazoles; Valine; Valsartan | 2008 |
Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Combination therapy versus monotherapy as initial treatment for stage 2 hypertension: a prespecified subgroup analysis of a community-based, randomized, open-label trial.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Reaching the therapeutic goal in hypertension: results from the Canadian valsartan observational study. (Diovantage 4).
Topics: Aged; Antihypertensive Agents; Blood Pressure; Canada; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Improving blood pressure control: increase the dose of diuretic or switch to a fixed-dose angiotensin receptor blocker/diuretic? the valsartan hydrochlorothiazide diuretic for initial control and titration to achieve optimal therapeutic effect (Val-DICTAT
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Chi-Square Distribution; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Least-Squares Analysis; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Efficacy and tolerability of combination therapy with valsartan/hydrochlorothiazide in the initial treatment of severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Achieving BP goals with valsartan and HCTZ alone and in combination: pooled analysis of two randomized, double-blind, placebo-controlled studies.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2008 |
Combination therapy with valsartan/hydrochlorothiazide at doses up to 320/25 mg improves blood pressure levels in patients with hypertension inadequately controlled by valsartan 320 mg monotherapy.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2008 |
Combination antihypertensive therapy with valsartan and hydrochlorothiazide in Chinese patients with mild-to-moderate hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Asian People; Blood Pressure; China; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Initial combination therapy compared with monotherapy in diabetic hypertensive patients.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Glucose; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypoglycemic Agents; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Metabolic and antihypertensive effects of combined angiotensin receptor blocker and diuretic therapy in prediabetic hypertensive patients with the cardiometabolic syndrome.
Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metabolic Syndrome; Middle Aged; Prediabetic State; Risk Factors; Tetrazoles; Valine; Valsartan; Young Adult | 2008 |
Effects of high sodium intake and diuretics on the circadian rhythm of blood pressure in type 2 diabetic patients treated with an angiotensin II receptor blocker.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Prospective Studies; Sodium; Sodium, Dietary; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Impact of supportive measures on drug adherence in patients with essential hypertension treated with valsartan: the randomized, open-label, parallel group study VALIDATE.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Middle Aged; Tetrazoles; Valine; Valsartan | 2009 |
Impact of angiotensin receptor blockade in combination with hydrochlorothiazide 25 mg in 2121 patients with stage 1-2 hypertension.
Topics: Adult; Age Factors; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Racial Groups; Sex Factors; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Effects of force-titrated valsartan/hydrochlorothiazide versus amlodipine/hydrochlorothiazide on ambulatory blood pressure in patients with stage 2 hypertension: the EVALUATE study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Triple antihypertensive therapy with amlodipine, valsartan, and hydrochlorothiazide: a randomized clinical trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Single-Blind Method; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Combination therapy with various combinations of aliskiren, valsartan, and hydrochlorothiazide in hypertensive patients not adequately responsive to hydrochlorothiazide alone.
Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2009 |
Simultaneous determination of losartan and hydrochlorothiazide in human plasma by LC/MS/MS with electrospray ionization and its application to pharmacokinetics.
Topics: Administration, Oral; Adult; Chlorthalidone; Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Humans; Hydrochlorothiazide; Losartan; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tetrazoles; Therapeutic Equivalency; Valine; Valsartan | 2009 |
Randomized study to compare valsartan +/- HCTZ versus amlodipine +/- HCTZ strategies to maximize blood pressure control.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; South America; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2009 |
Effectiveness of initiating treatment with valsartan/hydrochlorothiazide in patients with stage-1 or stage-2 hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Amlodipine/valsartan/hydrochlorothiazide triple combination therapy in moderate/severe hypertension: Secondary analyses evaluating efficacy and safety.
Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2009 |
Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Imidazoles; Irbesartan; Kidney Tubules; Losartan; Single-Blind Method; Tetrazoles; Valine; Valsartan | 2010 |
Achieving blood pressure goal: initial therapy with valsartan/hydrochlorothiazide combination compared with monotherapy.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebo Effect; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2010 |
Angiotensin receptor blocker/diuretic combination preserves insulin responses in obese hypertensives.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Gender-specific, multi-level determinants of outcomes of antihypertensive treatment: a sub-analysis of the Belgian PREVIEW study.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Belgium; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patients; Physicians; Prospective Studies; Sex Characteristics; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan | 2011 |
Evaluation of pharmacokinetic interactions between amlodipine, valsartan, and hydrochlorothiazide in patients with hypertension.
Topics: Adolescent; Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
24-Hour ambulatory blood pressure response to combination valsartan/hydrochlorothiazide and amlodipine/hydrochlorothiazide in stage 2 hypertension by ethnicity: the EVALUATE study.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Racial Groups; Regression Analysis; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amides; Antihypertensive Agents; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Comparison of the antihypertensive efficacy of irbesartan/HCTZ and valsartan/HCTZ combination therapy: impact of age and gender.
Topics: Adolescent; Adult; Age Factors; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Sex Characteristics; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
24-Hour ambulatory blood pressure control with triple-therapy amlodipine, valsartan and hydrochlorothiazide in patients with moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Rationale and design of the Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial.
Topics: Adult; Africa South of the Sahara; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Research Design; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
Effect of valsartan, hydrochlorothiazide, and their combination on 24-h ambulatory blood pressure response in elderly patients with systolic hypertension: a ValVET substudy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2011 |
Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXA
Topics: Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan | 2011 |
Chronotherapy with valsartan/hydrochlorothiazide combination in essential hypertension: improved sleep-time blood pressure control with bedtime dosing.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Treating systolic hypertension in the very elderly with valsartan-hydrochlorothiazide vs. either monotherapy: ValVET primary results.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Office and ambulatory blood pressure-lowering effects of combination valsartan/hydrochlorothiazide vs. hydrochlorothiazide-based therapy in obese, hypertensive patients.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity; Office Visits; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Pharmacokinetic profiles of hydrochlorothiazide alone and in combination with benazepril or valsartan in healthy Chinese volunteers: evaluation of the potential interaction.
Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cross-Over Studies; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Distinct effects of fixed combinations of valsartan with either amlodipine or hydrochlorothiazide on lipoprotein subfraction profile in patients with hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cholesterol; Female; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Particle Size; Tetrazoles; Triglycerides; Valine; Valsartan | 2013 |
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Antihypertensive and metabolic effects of Angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive African American and white patients.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Black or African American; Blood Glucose; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Insulin; Intention to Treat Analysis; Male; Middle Aged; Obesity, Abdominal; Prediabetic State; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People | 2013 |
Antihypertensive response to thiazide diuretic or angiotensin receptor blocker in elderly hypertensives is not influenced by pretreatment plasma renin activity.
Topics: Age Factors; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2012 |
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2012 |
[Effects of valsartan combined with amlodipine or hydrochlorothiazide regimen on blood pressure variation in elderly hypertensive patients].
Topics: Aged; Amlodipine; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Effects of valsartan or ramipril addition to amlodipine/hydrochlorothiazide combination on left ventricular mass in diabetic hypertensive patients with left ventricular hypertrophy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Ramipril; Tetrazoles; Valine; Valsartan | 2012 |
Comparison of the efficacy and safety profiles of two fixed-dose combinations of antihypertensive agents, amlodipine/benazepril versus valsartan/hydrochlorothiazide, in patients with type 2 diabetes mellitus and hypertension: a 16-week, multicenter, rando
Topics: Aged; Albuminuria; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Treatment Outcome; Uric Acid; Valine; Valsartan | 2012 |
Cardiovascular outcomes in hypertensive patients: comparing single-agent therapy with combination therapy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Prognosis; Retrospective Studies; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Effects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Continuous Positive Airway Pressure; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Manometry; Middle Aged; Polysomnography; Predictive Value of Tests; Pulse Wave Analysis; Risk Factors; Russia; Severity of Illness Index; Sleep Apnea, Obstructive; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vascular Stiffness | 2013 |
Effects of demographics on the antihypertensive efficacy of triple therapy with amlodipine, valsartan, and hydrochlorothiazide for moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Demography; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Valine; Valsartan; Young Adult | 2013 |
Pharmacokinetic interactions of valsartan and hydrochlorothiazide: an open-label, randomized, 4-period crossover study in healthy Egyptian male volunteers.
Topics: Administration, Oral; Antihypertensive Agents; Cross-Over Studies; Drug Therapy, Combination; Egypt; Healthy Volunteers; Humans; Hydrochlorothiazide; Male; Patient Compliance; Tetrazoles; Valine; Valsartan | 2013 |
Efficacy of newer versus older antihypertensive drugs in black patients living in sub-Saharan Africa.
Topics: Adult; Africa South of the Sahara; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Effect of renin-angiotensin system blockade on soluble Klotho in patients with type 2 diabetes, systolic hypertension, and albuminuria.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Female; Glucuronidase; Hospitals, University; Humans; Hydrochlorothiazide; Hypertension; Klotho Proteins; London; Male; Middle Aged; Phosphates; Pulse Wave Analysis; Renin-Angiotensin System; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2013 |
[Troubleshooting of bioinequivalence of compound valsartan tablets].
Topics: Administration, Oral; Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Area Under Curve; Chromatography, Liquid; Cross-Over Studies; Drug Liberation; Humans; Hydrochlorothiazide; Male; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Valsartan; Young Adult | 2014 |
[Optimization of arterial hypertension management by the use of two- and three-drugs fixed dose combinations at the daily stay department].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Day Care, Medical; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Polypill for the prevention of cardiovascular disease (PolyIran): study design and rationale for a pragmatic cluster randomized controlled trial.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Atorvastatin; Cardiovascular Agents; Cardiovascular Diseases; Clinical Protocols; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iran; Male; Middle Aged; Polypharmacy; Primary Prevention; Research Design; Secondary Prevention; Sodium Chloride Symporter Inhibitors; Time Factors; Treatment Outcome; Valsartan | 2015 |
Time of administration important? Morning versus evening dosing of valsartan.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Risk Factors; Treatment Outcome; Valsartan | 2015 |
Long-term safety of nebivolol and valsartan combination therapy in patients with hypertension: an open-label, single-arm, multicenter study.
Topics: Antihypertensive Agents; Benzopyrans; Drug Combinations; Ethanolamines; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nebivolol; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Assessment of glomerular filtration rate based on alterations of serum brain-derived neurotrophic factor in type 2 diabetic subjects treated with amlodipine/benazepril or valsartan/hydrochlorothiazide.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Male; Middle Aged; Valsartan | 2015 |
Choice of Antihypertensive Combination Therapy Based on Daily Salt Intake.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metabolic Syndrome; Middle Aged; Potassium; Prospective Studies; Sodium; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2015 |
PolyPill for Prevention of Cardiovascular Disease in an Urban Iranian Population with Special Focus on Nonalcoholic Steatohepatitis: A Pragmatic Randomized Controlled Trial within a Cohort (PolyIran - Liver) - Study Protocol.
Topics: Angiotensin II Type 1 Receptor Blockers; Aspirin; Atorvastatin; Cardiovascular Diseases; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iran; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Platelet Aggregation Inhibitors; Urban Population; Valsartan | 2015 |
Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Area Under Curve; Arizona; Biphenyl Compounds; Calcium Channel Blockers; Carbazoles; Carvedilol; Cross-Over Studies; Diuretics; Drug Administration Schedule; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Hydrochlorothiazide; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Neprilysin; Propanolamines; Protease Inhibitors; Tetrazoles; Valsartan | 2015 |
The efficacy and safety of valsartan and combination of valsartan and hydrochlorothiazide in the treatment of patients with mild to moderate arterial hypertension - the VICTORY trial.
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Safety; Prospective Studies; Treatment Outcome; Valsartan | 2017 |
Saliva versus Plasma Bioequivalence of Valsartan/Hydrochlorothiazide in Humans: Validation of Classes II and IV Drugs of the Salivary Excretion Classification System.
Topics: Administration, Oral; Antihypertensive Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Fasting; Healthy Volunteers; Humans; Hydrochlorothiazide; Male; Saliva; Salivary Elimination; Therapeutic Equivalency; Valsartan | 2018 |
Patient characteristics do not predict the individual response to antihypertensive medication: a cross-over trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Family Practice; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Netherlands; Practice Guidelines as Topic; Prognosis; Prospective Studies; Valsartan | 2018 |
The efficacy and safety of valsartan and a combination of valsartan and hydrochlorothiazide in the treatment of patients with mild to moderate arterial hypertension: a subgroup analysis of the effect of valsartan and its combination with….
Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Treatment Outcome; Valsartan | 2018 |
Comparative effects of valsartan plus either cilnidipine or hydrochlorothiazide on home morning blood pressure surge evaluated by information and communication technology-based nocturnal home blood pressure monitoring.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Blood Pressure Monitors; Dihydropyridines; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Medical Informatics; Middle Aged; Outcome Assessment, Health Care; Valsartan | 2018 |
Clinical efficacy and ultrasound inspection of the treatment of hypertensive heart patients with Valsartan combined with hydrochlorothiazide.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Echocardiography; Female; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome; Valsartan; Ventricular Function, Left | 2018 |
A multicenter, randomized, and double-blind phase IV clinical trial to compare the efficacy and safety of fixed-dose combinations of amlodipine orotate/valsartan 5/160 mg versus valsartan/hydrochlorothiazide 160/12.5 mg in patients with essential hyperten
Topics: Aged; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Treatment Outcome; Valsartan | 2018 |
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Cardiovascular Agents; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Secondary Prevention; Valsartan | 2019 |
Circulating microparticles and central blood pressure according to antihypertensive strategy.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cell-Derived Microparticles; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Rosuvastatin Calcium; Valsartan | 2019 |
Comparative effects of valsartan plus cilnidipine or hydrochlorothiazide on nocturnal home blood pressure.
Topics: Antihypertensive Agents; Blood Pressure; Dihydropyridines; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2021 |
70 other study(ies) available for hydrochlorothiazide and valsartan
| Article | Year |
|---|---|
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Effects of valsartan and hydrochlorothiazide alone and in combination on blood pressure and heart rate in conscious-telemetered spontaneously hypertensive rats (SHR).
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Telemetry; Tetrazoles; Valine; Valsartan | 1998 |
By the way, doctor... I am 87 and have been taking blood pressure medications for years. In the past, side effects were a problem, but for about the last year I've done very well taking valsartan (Diovan) and hydrochlorothiazide (Esidrex). Now My blood pr
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Systole; Tetrazoles; Valine; Valsartan | 2000 |
Simultaneous determination of valsartan and hydrochlorothiazide in tablets by first-derivative ultraviolet spectrophotometry and LC.
Topics: Antihypertensive Agents; Chromatography, High Pressure Liquid; Diuretics; Drug Combinations; Hydrochlorothiazide; Reproducibility of Results; Sodium Chloride Symporter Inhibitors; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan | 2001 |
[Fixed combination of AT1 blocker and diuretic. Stroke preventive combination for hypertension].
Topics: Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
[High dose sartan plus thiazide. Power duo in hypertension].
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2003 |
[High dose sartan plus diuretic. More power in hypertension and its sequelae].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Combinations; Heart Rate; Hydrochlorothiazide; Hypertension; Receptor, Angiotensin, Type 1; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
[Episodes of depression with attempted suicide after taking valsartan with hydrochlorothiazide].
Topics: Adult; Antihypertensive Agents; Depression; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Suicide, Attempted; Tetrazoles; Valine; Valsartan | 2003 |
[AT-1 blockers are different in their effects. The forgetful patients begin to notice it especially].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diuretics; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Losartan; Meta-Analysis as Topic; Placebos; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Stroke; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
[First fixed combination of sartan and high-dosage diuretic. A strong duo against high blood pressure].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Patient Compliance; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2004 |
[New combination of high dosage sartan and 25 mg HCT. Systolic blood pressure lowered by 21 mmHg].
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan | 2004 |
[VALUE study underscores the significance of reaching aimed blood pressure values for minimizing cardiovascular risks].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
Automated office and home phone-transmitted blood pressure recordings in uncontrolled hypertension treated with valsartan and hydrochlorothiazide.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Automation; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oscillometry; Telephone; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
Blood pressure control with valsartan and hydrochlorothiazide in clinical practice: the MACHT Observational Study.
Topics: Aged; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2006 |
Hematuria in a patient with class IV lupus nephritis.
Topics: Antihypertensive Agents; Biopsy; Cyclophosphamide; El Salvador; Female; Follow-Up Studies; Glomerular Basement Membrane; Glomerular Mesangium; Glucocorticoids; Hematuria; Hispanic or Latino; Humans; Hydrochlorothiazide; Hydroxychloroquine; Hypertension; Immunosuppressive Agents; Kidney Glomerulus; Lisinopril; Lupus Nephritis; Middle Aged; Nifedipine; Prednisone; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2006 |
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers.
Topics: Adolescent; Adult; Amides; Amlodipine; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2006 |
A liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of valsartan and hydrochlorothiazide in human plasma.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tetrazoles; Valine; Valsartan | 2007 |
[Blood pressure lowering and risk reduction under treatment with valsartan and its combination with hydrochlorothiazide (HCT)].
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Prospective Studies; Risk Factors; Tetrazoles; Valine; Valsartan | 2006 |
Antihypertensive therapies.
Topics: Amides; Antihypertensive Agents; Blood Pressure; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diuretics; Drug Design; Drug Industry; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Renin; Tetrazoles; Valine; Valsartan | 2007 |
Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis.
Topics: Aged; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Double-Blind Method; Drug Therapy, Combination; France; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Losartan; Perindopril; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Adherence with multiple-combination antihypertensive pharmacotherapies in a US managed care database.
Topics: Adolescent; Adult; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Insurance Claim Review; Male; Managed Care Programs; Middle Aged; Patient Compliance; Tetrazoles; United States; Valine; Valsartan | 2008 |
Assessment of adherence, persistence, and costs among valsartan and hydrochlorothiazide retrospective cohorts in free-and fixed-dose combinations.
Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cohort Studies; Diuretics; Drug Combinations; Drug Costs; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Patient Compliance; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2008 |
Triple fixed-dose combination therapy: back to the past.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Exforge HCT.
Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Costs; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
The role of baseline blood pressure in guiding treatment choice: a secondary analysis of the use of valsartan/hydrochlorothiazide as initial therapy in hypertensive adults in a randomized, double-blind, placebo-controlled trial.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Amlodipine/valsartan/hydrochlorothiazide: fixed-dose combination in hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials, Phase III as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: an update.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2010 |
Economic evaluation of irbesartan in combination with hydrochlorothiazide in the treatment of hypertension in Greece.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Combinations; Female; Greece; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Male; Markov Chains; Middle Aged; Models, Economic; Quality of Life; Sex Factors; Tetrazoles; Valine; Valsartan | 2011 |
Determinants of masked hypertension in hypertensive patients treated in a primary care setting.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Comorbidity; Diabetes Complications; Drug Therapy, Combination; Dyslipidemias; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Masked Hypertension; Middle Aged; Obesity; Prevalence; Primary Health Care; Quebec; Risk; Tetrazoles; Valine; Valsartan; White Coat Hypertension | 2012 |
Do placebo based validation standards mimic real batch products behaviour? Case studies.
Topics: Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Metformin; Parabens; Pharmaceutical Preparations; Placebos; Quality Control; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan | 2011 |
Simultaneous spectrophotometric determination of valsartan and hydrochlorothiazide by H-point standard addition method and partial least squares regression.
Topics: Antihypertensive Agents; Calibration; Hydrochlorothiazide; Least-Squares Analysis; Spectrophotometry, Ultraviolet; Tetrazoles; Valine; Valsartan | 2011 |
Efficacy, safety, and tolerability of valsartan/hydrochlorothiazide in Asian patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Asia; Asian People; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pacific Islands; Tetrazoles; Valine; Valsartan; Young Adult | 2011 |
Amlodipine + valsartan + hydrochlorothiazide. A 3-drug fixed-dose combination for hypertension: too many drawbacks.
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Packaging; Humans; Hydrochlorothiazide; Hypertension; Medication Errors; Tetrazoles; Valine; Valsartan | 2011 |
Modelling of blood pressure and total cardiovascular risk outcomes after second-line valsartan therapy: the BSCORE study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Linear Models; Logistic Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Assessment; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2011 |
Comparison of the efficacy and safety of single-pill fixed-dose combinations of losartan/hydrochlorothiazide and valsartan/hydrochlorothiazide in patients with hypertension (SALT-VAT study).
Topics: Aged; Blood Pressure; Drug Combinations; Drug Substitution; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Simple RP-HPLC method for determination of triple drug combination of valsartan, amlodipine and hydrochlorothiazide in human plasma.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diuretics; Drug Therapy, Combination; Guideline Adherence; Guidelines as Topic; Humans; Hydrochlorothiazide; Reproducibility of Results; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2012 |
Does response of RAS blockade on serum K+ levels influence its glycemic-mitigating response when combined with hydrochlorothiazide?
Topics: Aged; Antihypertensive Agents; Blood Glucose; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Obesity, Abdominal; Outpatients; Postprandial Period; Potassium; Renin-Angiotensin System; Statistics as Topic; Tetrazoles; Valine; Valsartan | 2012 |
Comparative efficacy of irbesartan/ hydrochlorothiazide and valsartan/hydrochlorothiazide combination in lowering blood pressure: a retrospective observational study in Oman.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Oman; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2013 |
Concurrent estimation of amlodipine besylate, hydrochlorothiazide and valsartan by RP-HPLC, HPTLC and UV-spectrophotometry.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; Hydrochlorothiazide; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan | 2014 |
Pill burden in hypertensive patients treated with single-pill combination therapy--an observational study.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cost of Illness; Drug Combinations; Drug Therapy, Combination; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2013 |
Comparative study between derivative spectrophotometry and multivariate calibration as analytical tools applied for the simultaneous quantitation of Amlodipine, Valsartan and Hydrochlorothiazide.
Topics: Amlodipine; Calibration; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Least-Squares Analysis; Multivariate Analysis; Reproducibility of Results; Spectrophotometry; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan | 2013 |
Different approaches in Partial Least Squares and Artificial Neural Network models applied for the analysis of a ternary mixture of Amlodipine, Valsartan and Hydrochlorothiazide.
Topics: Amlodipine; Antihypertensive Agents; Dosage Forms; Hydrochlorothiazide; Least-Squares Analysis; Neural Networks, Computer; Principal Component Analysis; Spectrophotometry, Ultraviolet; Tetrazoles; Valine; Valsartan | 2014 |
Parkinsonism and severe hypothyroidism in an elderly patient: a case of lithium toxicity due to pharmacological interactions.
Topics: Aged; Antimanic Agents; Drug Combinations; Drug Interactions; Female; Humans; Hydrochlorothiazide; Hypothyroidism; Lithium Carbonate; Parkinsonian Disorders; Severity of Illness Index; Tetrazoles; Valine; Valsartan | 2014 |
[Process monitoring of dissolution of valsartan and hydrochlorothiazide tablets by fiber-chemical sensor assisted by mathematical separation model of linear equations].
Topics: Chromatography, High Pressure Liquid; Hydrochlorothiazide; Models, Theoretical; Solubility; Tablets; Tetrazoles; Valine; Valsartan | 2014 |
Novel spectrophotometric methods for simultaneous determination of Amlodipine, Valsartan and Hydrochlorothiazide in their ternary mixture.
Topics: Amlodipine; Antihypertensive Agents; Hydrochlorothiazide; Limit of Detection; Spectrophotometry; Tetrazoles; Valine; Valsartan | 2015 |
Real-world effectiveness of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide in high-risk patients and other subgroups.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asia; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Middle East; Prospective Studies; Tablets; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2015 |
A new, rapid, stability-indicating UPLC method for separation and determination of impurities in amlodipine besylate, valsartan and hydrochlorothiazide in their combined tablet dosage form.
Topics: Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Hydrochlorothiazide; Limit of Detection; Reference Standards; Reproducibility of Results; Solutions; Tablets; Valsartan | 2015 |
Simultaneous determination of valsartan, amlodipine besylate and hydrochlorothiazide using capillary zone electrophoresis (CZE).
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Calibration; Diuretics; Drug Combinations; Electrophoresis, Capillary; Hydrochlorothiazide; Limit of Detection; Reference Standards; Reproducibility of Results; Tablets; Tetrazoles; Valine; Valsartan | 2015 |
Comparison of amlodipine/valsartan/hydrochlorothiazide single pill combination and free combination: adherence, persistence, healthcare utilization and costs.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cohort Studies; Drug Combinations; Female; Hospitalization; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Retrospective Studies; Valsartan | 2015 |
Influence of Age and Race on 24-Hour Ambulatory Blood Pressure Responses to Valsartan, Hydrochlorothiazide, and Their Combination: Implications for Clinical Practice.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome; Valsartan; White People; Young Adult | 2017 |
Hydrochlorothiazide modulates ischemic heart failure-induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Diuretics; Fibroblasts; Fibrosis; Furosemide; Heart Failure; Heart Ventricles; Hydrochlorothiazide; Male; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Recovery of Function; Signal Transduction; Smad2 Protein; Stroke Volume; Transforming Growth Factor beta1; Valsartan; Ventricular Function, Left; Ventricular Remodeling | 2017 |
Novel Pure Component Contribution Algorithm (PCCA) and UHPLC Methods for Separation and Quantification of Amlodipine, Valsartan, and Hydrochlorothiazide in Ternary Mixture.
Topics: Algorithms; Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Tablets; Valsartan | 2017 |
Evaluation of Drug-Induced Photosensitivity Using the Japanese Adverse Drug Event Report (JADER) Database.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Humans; Hydrochlorothiazide; Incidence; Japan; Ketoprofen; Losartan; Male; Middle Aged; Odds Ratio; Photosensitivity Disorders; Seasons; Sodium Chloride Symporter Inhibitors; Valsartan; Young Adult | 2017 |
Identification and structure elucidation of a new degradation impurity in the multi-component tablets of amlodipine besylate.
Topics: Amlodipine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; Drug Contamination; Drug Stability; Excipients; Formaldehyde; Hydrochlorothiazide; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Time Factors; Valsartan | 2019 |
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan | 2019 |
Effects of Different Antihypertensive Drug Combinations on Blood Pressure and Arterial Stiffness.
Topics: Aged; Amlodipine; Antihypertensive Agents; Arteries; Blood Pressure; Diastole; Drug Combinations; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Lisinopril; Losartan; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Systole; Valsartan; Vascular Resistance; Vascular Stiffness | 2019 |
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan | 2020 |
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan | 2020 |
High performance liquid chromatographic assay of amlodipine, valsartan and hydrochlorothiazide simultaneously and its application to pharmaceuticals, urine and plasma analysis.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Limit of Detection; Linear Models; Reproducibility of Results; Tablets; Valsartan | 2020 |
Development and Validation of a UPLC-DAD Method for the Simultaneous Quantification of Eight Antihypertensive Drugs in the Pharmaceutical Matrix.
Topics: Amlodipine; Antihypertensive Agents; Humans; Hydrochlorothiazide; Pharmaceutical Preparations; Tetrazoles; Valsartan | 2021 |
Eco-friendly spectrophotometric evaluation of triple-combination therapies in the treatment strategy of patients suffering from hypertension during coronavirus pandemic - Spectralprint recognition study.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronavirus; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Pandemics; Spectrophotometry; Valsartan | 2022 |
NITROSOGENESIS LESSONS FROM DERMATOLOGISTS-NITROSAMINES/ NDSRIS CONTAMINATION OF THE POLIMEDICATION IN POLIMORBID PATIENTS AS THE MOST POWERFUL SKIN CANCER INDUCTOR: DOUBLE HATCHET FLAP FOR SCC OF THE SCALP OCCURRING DURING TREATMENT WITH VALSARTAN/ HYDRO
Topics: Aged, 80 and over; Carcinogens; Carcinoma, Squamous Cell; Dermatologists; Humans; Hydrochlorothiazide; Nitrosamines; Quality of Life; Scalp; Skin Neoplasms; Valsartan | 2023 |