hydrochlorothiazide and thiophenes

hydrochlorothiazide has been researched along with thiophenes in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199012 (46.15)18.7374
1990's2 (7.69)18.2507
2000's7 (26.92)29.6817
2010's4 (15.38)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Baverel, G; Gougoux, A; Kiss, A; Lemieux, G; Vinay, P2
Beauchemin, M; Gougoux, A; Lemieux, G; Vinay, P1
Freis, ED; Kyle, MC; Nemati, M1
Chrysant, SG; de Carvalho, JG; Dunn, FG; Frohlich, ED1
Gillies, AH; Morgan, TO1
Miller, SA; Vertes, V1
Furrer, J; Siegenthaler, W; Vetter, W1
Dupont, P; Lamy, F; Wauthier, P1
Alexander, F; Dubb, JW; Familiar, RG; Stote, RM1
Hamilton, BP; Hamilton, J; Kuzbida, G; Levinson, P; Mersey, JH; Pavlis, R1
Elliott, WJ1
Sega, R1
Levine, B1
Jäger, B; Sachse, A; Verboom, CN1
Khan, BV; Khan, QA; Lauten, WB; Navalkar, S; Parthasarathy, S; Rahman, ST1
Böhm, M; Sachse, A1
Punzi, CF; Punzi, HA1
Conter, HS; McKay, DW; Reiz, RJ1
Plosker, GL1
Ambrosioni, E; Bombelli, M; Cerasola, G; Cipollone, F; Ferri, C; Grazioli, I; Leprotti, C; Mancia, G; Melzi, G; Mugellini, A; Mulè, G; Palasciano, G; Salvetti, A; Trimarco, B1
Kahner-Gröne, S; Köneke, D; Marggraf, K; Nüdling, S; Palissa, H1
Hacioğlu, F; Onal, A1
Devineni, D; Polidori, D; Rusch, S; Vaccaro, N; Wajs, E1
Abdelsalam, RA; Haddad, GM; Marghany, KA1

Reviews

2 review(s) available for hydrochlorothiazide and thiophenes

ArticleYear
Safety and tolerability of eprosartan in combination with hydrochlorothiazide.
    Drug safety, 2002, Volume: 25, Issue:8

    Topics: Acrylates; Age Factors; Antihypertensive Agents; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Thiophenes

2002
Eprosartan: a review of its use in hypertension.
    Drugs, 2009, Volume: 69, Issue:17

    Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Clinical Trials as Topic; Cough; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Nitrendipine; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Recurrence; Risk Factors; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome

2009

Trials

17 trial(s) available for hydrochlorothiazide and thiophenes

ArticleYear
Treatment of arterial hypertension with tienilic acid, a new diuretic with uricosuric properties.
    Canadian Medical Association journal, 1978, May-06, Volume: 118, Issue:9

    Topics: Adult; Blood Pressure; Blood Urea Nitrogen; Calcium; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Evaluation; Electrocardiography; Electrolytes; Female; Glycolates; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Hypertension; Male; Middle Aged; Phenoxyacetates; Thiophenes; Uric Acid; Uricosuric Agents

1978
Clinical study of ticrynafen. A new diuretic, antihypertensive, and uricosuric agent.
    JAMA, 1977, Feb-14, Volume: 237, Issue:7

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Drug Evaluation; Glycolates; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Phenoxyacetates; Thiophenes; Uric Acid; Uricosuric Agents

1977
Ticrynafen: a novel uricosuric antihypertensive natriuretic agent.
    Archives of internal medicine, 1978, Volume: 138, Issue:1

    Topics: Blood Pressure; Blood Urea Nitrogen; Blood Volume; Body Weight; Clinical Trials as Topic; Creatinine; Double-Blind Method; Glomerular Filtration Rate; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Natriuresis; Phenoxyacetates; Potassium; Thiophenes; Uric Acid; Uricosuric Agents

1978
A double-blind comparison of the effects of hydrochlorothiazide and tienylic acid (a diuretic with uricosuric properties) in hypertension.
    British journal of clinical pharmacology, 1978, Volume: 6, Issue:4

    Topics: Adult; Aged; Blood Pressure; Blood Urea Nitrogen; Body Weight; Carbon Dioxide; Chlorides; Clinical Trials as Topic; Creatinine; Diuretics; Double-Blind Method; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Liver Function Tests; Male; Middle Aged; Phenoxyacetates; Phosphates; Potassium; Sodium; Thiophenes; Uric Acid

1978
Ticrynafen and hydrochlorothiazide. A double-blind study of antihypertensive properties with an open crossover.
    JAMA, 1979, May-18, Volume: 241, Issue:20

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Phenoxyacetates; Placebos; Thiophenes; Uric Acid

1979
[Experiences with a new hypouricemic diuretic (tienilic acid): comparison with hydrochlorothiazide].
    Schweizerische medizinische Wochenschrift, 1978, Dec-09, Volume: 108, Issue:49

    Topics: Adult; Clinical Trials as Topic; Diuretics; Female; Glycolates; Heart Arrest; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Phenoxyacetates; Systole; Thiophenes; Uric Acid

1978
Comparative effects of ticrynafen and hydrochlorothiazide in the treatment of hypertension.
    The New England journal of medicine, 1979, 08-09, Volume: 301, Issue:6

    Topics: Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Phenoxyacetates; Random Allocation; Thiophenes; Uric Acid; Uricosuric Agents

1979
Double blind clinical study of tienilic acid and hydrochlorothiazide in primary arterial hypertension.
    Acta clinica Belgica, 1979, Volume: 34, Issue:2

    Topics: Adult; Aged; Blood Pressure; Diuretics; Double-Blind Method; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Phenoxyacetates; Posture; Thiophenes; Time Factors

1979
Double-blind comparison of eprosartan and enalapril on cough and blood pressure in unselected hypertensive patients. Eprosartan Study Group.
    Journal of human hypertension, 1999, Volume: 13, Issue:6

    Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cough; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Risk Factors; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Surveys and Questionnaires; Thiophenes; Treatment Outcome

1999
Efficacy and safety of eprosartan in severe hypertension. Eprosartan Multinational Study Group.
    Blood pressure, 1999, Volume: 8, Issue:2

    Topics: Acrylates; Administration, Oral; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Thiophenes

1999
Eprosartan provides safe and effective long-term maintenance of blood pressure control in patients with mild to moderate essential hypertension.
    Current medical research and opinion, 2001, Volume: 17, Issue:1

    Topics: Acrylates; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Canada; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome; United States

2001
Efficacy of eprosartan in combination with HCTZ in patients with essential hypertension.
    Journal of human hypertension, 2002, Volume: 16, Issue:3

    Topics: Acrylates; Adult; Aged; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Thiophenes

2002
Once-daily eprosartan mesylate in the treatment of elderly patients with isolated systolic hypertension: data from a 13-week double-blind, placebo-controlled, parallel, multicenter study.
    Journal of human hypertension, 2004, Volume: 18, Issue:9

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome

2004
Eprosartan mesylate effectively reduces systolic and diastolic blood pressure in a Canadian primary care setting.
    The Canadian journal of cardiology, 2004, Volume: 20 Suppl C

    Topics: Acrylates; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Blood Pressure Determination; Canada; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Probability; Prospective Studies; Reference Values; Severity of Illness Index; Single-Blind Method; Systole; Thiophenes; Treatment Outcome

2004
Ambulatory monitoring of systolic hypertension in the elderly: Eprosartan/hydrochlorothiazide compared with losartan/hydrochlorothiazide (INSIST trial).
    Advances in therapy, 2010, Volume: 27, Issue:6

    Topics: Acrylates; Aged; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Office Visits; Severity of Illness Index; Statistics, Nonparametric; Systole; Thiophenes; Treatment Outcome

2010
[Adjustment of antihypertensive therapy to a generic eprosartan preparation. Results of a non-interventional study].
    MMW Fortschritte der Medizin, 2010, Oct-14, Volume: 152 Suppl 3

    Topics: Acrylates; Aged; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cost Savings; Drug Combinations; Drug Costs; Drug Substitution; Drugs, Generic; Female; Humans; Hydrochlorothiazide; Imidazoles; Male; Middle Aged; National Health Programs; Prospective Studies; Thiophenes

2010
Effects of hydrochlorothiazide on the pharmacokinetics, pharmacodynamics, and tolerability of canagliflozin, a sodium glucose co-transporter 2 inhibitor, in healthy participants.
    Clinical therapeutics, 2014, Volume: 36, Issue:5

    Topics: Adolescent; Adult; Blood; Canagliflozin; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucosides; Healthy Volunteers; Humans; Hydrochlorothiazide; Male; Middle Aged; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes; Urine; Young Adult

2014

Other Studies

7 other study(ies) available for hydrochlorothiazide and thiophenes

ArticleYear
The metabolic effects of tienilic acid, a new diuretic with uricosuric properties in man and dog.
    Advances in experimental medicine and biology, 1977, Volume: 76B

    Topics: Alkalosis; Animals; Biological Transport; Calcium; Chickens; Diuretics; Dogs; Glycolates; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kidney Tubules; p-Aminohippuric Acid; Phenoxyacetates; Potassium; Rabbits; Thiophenes; Uric Acid; Uricosuric Agents

1977
Metabolic effects in man of tienilic acid, a new diuretic with uricosuric properties.
    Nephron, 1978, Volume: 20, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Body Weight; Diuretics; Electrolytes; Glycolates; Humans; Hydrochlorothiazide; Phenoxyacetates; Thiophenes; Uric Acid; Uricosuric Agents

1978
Ticrynafen, a uricosuric antihypertensive diuretic.
    Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:4

    Topics: Adult; Antihypertensive Agents; Chlorthalidone; Diuretics; Drug Interactions; Ethacrynic Acid; Furosemide; Glycolates; Humans; Hydrochlorothiazide; Male; Natriuresis; Phenoxyacetates; Thiophenes; Uricosuric Agents

1978
Withdrawal phenomena in subjects with essential hypertension on clonidine or tiamenidine.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:5

    Topics: Adult; Blood Pressure; Clonidine; Epinephrine; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Pulse; Random Allocation; Substance Withdrawal Syndrome; Thiophenes

1984
Effects of eprosartan versus hydrochlorothiazide on markers of vascular oxidation and inflammation and blood pressure (renin-angiotensin system antagonists, oxidation, and inflammation).
    The American journal of cardiology, 2002, Mar-15, Volume: 89, Issue:6

    Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Chemokine CCL2; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Inflammation; Lipoproteins, LDL; Male; Middle Aged; Muscle, Smooth, Vascular; Oxidation-Reduction; Receptors, Angiotensin; Renin-Angiotensin System; Thiophenes; Treatment Outcome; Vascular Cell Adhesion Molecule-1

2002
Determination of eprosartan mesylate and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods.
    Journal of chromatographic science, 2012, Volume: 50, Issue:8

    Topics: Acrylates; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Hydrochlorothiazide; Imidazoles; Tablets; Thiophenes

2012
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
    Journal of separation science, 2020, Volume: 43, Issue:8

    Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan

2020