hydrochlorothiazide and ramipril

hydrochlorothiazide has been researched along with ramipril in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (4.62)	18.7374
1990's	11 (16.92)	18.2507
2000's	21 (32.31)	29.6817
2010's	29 (44.62)	24.3611
2020's	1 (1.54)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cairns, V; Koch, GG; Phillips, JA	1
Bender, N; Breitstadt, A; Cairns, V; Froer, KL; Heidbreder, D; Langley, A	1
Bauer, B; Breitstadt, A; Cairns, V; Froer, KL; Heidbreder, D	1
Bauer, B; Lorenz, H; Zahlten, R	1
Baldes, L; Becker, RH; Treudler, M	2
Traub, O; Webb, RC	1
Bader, B; Braun, N; Erley, CM; Risler, T; Scheu, M; Wolf, S	1
Genthon, R	1
Bauer, B; Bender, N; Breitstadt, A; Cairns, V; Koch, G; Moreadith, C; Phillips, J; Priestley, C; Scholze, J; Vander Elst, E	1
Bauer, B; Bender, N; Breitstadt, A; Cairns, V; Froer, KL; Heidbreder, D	1
Lloyd, MC; Traub, O; Webb, RC	1
Hammerschmidt, R; Lohmann, FW; Schaaf, D	1
Alderman, MH; Devereux, RB; Keating, JO; Pickering, TG; Pini, R; Roman, MJ; Sealey, JE	1
Goos, M; Wagner, SN; Welke, F	1
Abounassif, MA; Al-Zaagi, IA; Belal, F; Gadkariem, EA	1
Brown, NJ; Kumar, S; Painter, CA; Vaughan, DE	1
Alonso, RM; Jiménez, RM; Prieto, JA	1
Kolloch, RE	1
Rappert, B	1
Williams, B	1
Bakris, GL; Demopoulos, LA; Fox, JC; Gleim, GW; Leight, K; Lewin, AJ; Sutradhar, SC	1
Daul, A; Nürnberger, J; Philipp, T	1
Bertoluci, MC; Oliveira, FR; Schmid, H; Schmidt, A; Thomazelli, FC; Uebel, D	1
Coelho, EB; da Silva, CA; Fazan, R; Nobre, F; Salgado, HC	1
Bizot, MN; Denouel, J; Dieterich, HA; Dole, WP; Kemp, C; Vaidyanathan, S; Valencia, J; Yeh, CM; Zhao, C	1
Barton, J; Dicker, P; Jensen, C; Mulcahy, D; Nussberger, J; O'Brien, E; Stanton, A	1
Grimm, E; Herrmann, D; Kintscher, U; Scholze, J; Unger, T	1
Ali, MA; Andersen, K; Constance, CM; Egan, B; Jin, J; Keefe, DL; Weinberger, MH	1
Cleveland, JM; Rolleri, RL; White, WB	1
Afzal, R; Pais, P; Pogue, J; Sigamani, A; Xavier, D; Yusuf, S	1
Afzal, R; Eikelboom, J; Gupta, R; Mohan, V; Pais, P; Sigamani, A; Teo, K; Thomas, N; Xavier, D; Yusuf, S	1
Chae, IH; Chang, HJ; Cho, YS; Choi, DJ; Chung, WY; Gwak, JJ; Kang, HJ; Kim, HS; Kim, MA; Kim, SH; Kim, YJ; Lee, HY; Park, JS; Youn, TJ; Zo, JH	1
Chakraborty, BS; Desai, J; Ghosh, C; Jha, V; Khamar, B; Patel, A; Shah, G; Shah, T	1
Gorski, JC; Lindamood, C; Ortiz, S; Rackley, R; Shaw, A	1
Circelli, M; Cremonesi, G; Fogari, R; Mugellini, A	1
Trenkwalder, P	1
Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Preti, P; Zoppi, A	1
Carey, KM; Comee, MR; Donovan, JL; Kanaan, AO	1
Afzal, R; Gao, P; Pais, P; Sigamani, A; Teo, KK; Xavier, D; Yusuf, S	1
Dussouil, AS; Gaudy-Marqueste, C; Grob, JJ; Mallet, S; Monestier, S; Richard, MA; Tasei, AM	1
Gomes, MA; Kohlmann, O; Nobre, F; Oigman, W; Pereira-Barretto, AC; Póvoa, R; Rocha, JC	1
Farinde, A	1
Caro, M; Castro, F; Conde, D	1
Chazova, IE; Martyniuk, TV	1
Agaliotis, GD; Andreadis, EA; Angelopoulos, ET; Kolyvas, GN; Mousoulis, CG; Mousoulis, GP	1
Dudhrejiya, AV; Patel, JR; Pethani, TM; Sheth, NR; Vachhani, AN	1
Angeloni, E; Lombardo, P; Pirelli, M; Refice, S; Vitaterna, A	1
Alexander, MR; Burley, JC; Khaled, SA; Roberts, CJ; Yang, J	1
Alföldi, S; Farsang, C; Ferenci, T; Simonyi, G	1
Ghanem, M; Mahasne, A; Maqboul, L; Zaid, AN; Zaid, H	1
Chauhan, AS; Jain, SK; Kulhari, H; Pooja, D; Singh, MK; Sistla, R	1
Cheruvu, HS; Devalapalli, MMR; Sampathi, S; Shivakumar, S; Veeravalli, VB; Yertha, T	1
Almajaan, A; Andrews, GP; Gilvary, GC; Healy, AM; Jones, DS; Kelleher, JF; Li, S; Madi, AM; Senta-Loys, Z; Tian, Y	1
Desai, N; Jangid, AG; Patel, B; Suhagia, BN	1
Fuhr, U; Holzgrabe, U; Kinzig, M; Schroeter, M; Sigaroudi, A; Sörgel, F; Stelzer, C; Wahl, O	1
Bosch, J; Dans, AL; Gamra, H; Gao, P; Joseph, P; Lopez, PC; Lopez-Jaramillo, P; Pais, P; Santoso, A; Talukder, S; Teo, K; Tyrwhitt, J; Xavier, D; Yeates, K; Yusoff, K; Yusuf, S	1
Bachmann, HS; Besser, M; Severing, AL; Stuermer, EK; Terberger, N	1
Abdulwahab, S; Eissa, MS; Elsonbaty, A; Hassan, WS; Serag, A	1

Reviews

4 review(s) available for hydrochlorothiazide and ramipril

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Protection against stroke and dementia: an update on the latest clinical trial evidence. Current hypertension reports, 2004, Volume: 6, Issue:4 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Cognition; Dementia; Hydrochlorothiazide; Ramipril; Stroke; Tetrazoles; Verapamil	2004
Combination delapril/manidipine as antihypertensive therapy in high-risk patients. Clinical drug investigation, 2011, Volume: 31, Issue:7 Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Dihydropyridines; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Irbesartan; Losartan; Nitrobenzenes; Obesity; Olmesartan Medoxomil; Piperazines; Ramipril; Tetrazoles; Valine; Valsartan	2011
A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke. The Annals of pharmacotherapy, 2012, Volume: 46, Issue:5 Topics: Antihypertensive Agents; Aspirin; Atenolol; Cardiovascular Diseases; Drug Combinations; Humans; Hydrochlorothiazide; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Primary Prevention; Ramipril; Simvastatin; Stroke	2012

Trials

26 trial(s) available for hydrochlorothiazide and ramipril

Article	Year
Combination of ramipril and hydrochlorothiazide in the treatment of mild to moderate hypertension: Part 1--A double-blind, comparative, multicenter study in nonresponders to ramipril monotherapy. Clinical cardiology, 1992, Volume: 15, Issue:12 Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Ramipril; Safety; Single-Blind Method	1992
Efficacy and safety of ramipril in combination with hydrochlorothiazide: results of a long-term study. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 2 Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bridged Bicyclo Compounds; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Ramipril; Uric Acid	1991
An open multicenter study to assess the long-term efficacy, tolerance, and safety of the oral angiotensin converting enzyme inhibitor ramipril in patients with mild to moderate essential hypertension. Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Patient Compliance; Ramipril; Random Allocation	1989
Renal hemodynamics in essential hypertensives treated with losartan. Clinical nephrology, 1995, Volume: 43 Suppl 1 Topics: Antihypertensive Agents; Biphenyl Compounds; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Imidazoles; Kidney; Losartan; Male; Middle Aged; Ramipril; Renal Circulation; Renin-Angiotensin System; Tetrazoles	1995
Study of the efficacy and safety of the combination ramipril 2.5 mg plus hydrochlorothiazide 12.5 mg in patients with mild-to-moderate hypertension. ATHES Study Group. International journal of clinical pharmacology research, 1994, Volume: 14, Issue:1 Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Ramipril	1994
Short report: ramipril and hydrochlorothiazide combination therapy in hypertension: a clinical trial of factorial design. The East Germany Collaborative Trial Group. Journal of hypertension, 1993, Volume: 11, Issue:2 Topics: Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Research Design	1993
Combination of ramipril and hydrochlorothiazide in the treatment of mild to moderate hypertension--Part 2: An open long-term study of efficacy and safety. Clinical cardiology, 1993, Volume: 16, Issue:1 Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Longitudinal Studies; Male; Middle Aged; Ramipril	1993
Monitoring antihypertensive therapy through blood pressure measurements taken casually, at rest, during exercise, and under outpatient conditions. Zeitschrift fur Kardiologie, 1996, Volume: 85 Suppl 3 Topics: Adult; Antihypertensive Agents; Blood Pressure Monitors; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exercise Test; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Reproducibility of Results	1996
Differential effects of angiotensin converting enzyme inhibition and diuretic therapy on reductions in ambulatory blood pressure, left ventricular mass, and vascular hypertrophy. American journal of hypertension, 1998, Volume: 11, Issue:4 Pt 1 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Artery, Common; Diuretics; Double-Blind Method; Female; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Ramipril; Renin-Angiotensin System	1998
ACE inhibition versus angiotensin type 1 receptor antagonism: differential effects on PAI-1 over time. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Insulin; Insulin Resistance; Losartan; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Ramipril; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Tissue Plasminogen Activator; Treatment Outcome	2002
The JNC 7 approach compared to conventional treatment in diabetic patients with hypertension: a double-blind trial of initial monotherapy vs. combination therapy. Journal of clinical hypertension (Greenwich, Conn.), 2004, Volume: 6, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chi-Square Distribution; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Ramipril; Treatment Outcome	2004
Urinary TGF-beta1 reduction related to a decrease of systolic blood pressure in patients with type 2 diabetes and clinical diabetic nephropathy. Diabetes research and clinical practice, 2006, Volume: 72, Issue:3 Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Captopril; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propranolol; Ramipril; Transforming Growth Factor beta1	2006
Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Patient Compliance; Ramipril; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles	2007
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study. Circulation, 2007, Apr-17, Volume: 115, Issue:15 Topics: Adult; Aged; Antihypertensive Agents; Appetite Depressants; Blood Pressure; Body Weight; Cyclobutanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Metoprolol; Middle Aged; Obesity; Prospective Studies; Ramipril; Treatment Outcome; Verapamil	2007
Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial. Journal of hypertension, 2008, Volume: 26, Issue:3 Topics: Administration, Oral; Adult; Amides; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Time Factors; Treatment Outcome	2008
Utility of semiautomatic clinic and 24-h ambulatory blood pressure measurements to evaluate combination therapy: the Ramipril-Hydrochlorothiazide Hypertension trial. Journal of human hypertension, 2008, Volume: 22, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Treatment Outcome	2008
The need to test the theories behind the Polypill: rationale behind the Indian Polycap Study. Nature clinical practice. Cardiovascular medicine, 2009, Volume: 6, Issue:2 Topics: Administration, Oral; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atenolol; Capsules; Cardiovascular Agents; Cardiovascular Diseases; Diuretics; Double-Blind Method; Drug Combinations; Drug Costs; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Platelet Aggregation Inhibitors; Primary Prevention; Ramipril; Research Design; Secondary Prevention; Simvastatin; Treatment Outcome	2009
Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial. Lancet (London, England), 2009, Apr-18, Volume: 373, Issue:9672 Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Atenolol; Cardiovascular Diseases; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Middle Aged; Platelet Aggregation Inhibitors; Ramipril; Risk Factors; Risk Reduction Behavior; Simvastatin; Treatment Outcome	2009
Efficacy and tolerability of two formulations of ramipril in Korean adults with mild to moderate essential hypertension: an 8-week, multicenter, prospective, randomized, open-label, parallel-group noninferiority trial. Clinical therapeutics, 2009, Volume: 31, Issue:5 Topics: Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Administration Schedule; Drugs, Generic; Female; Humans; Hydrochlorothiazide; Hypertension; Korea; Male; Middle Aged; Natriuretic Peptide, Brain; Prospective Studies; Ramipril; Severity of Illness Index; Treatment Outcome; Ventricular Function, Left	2009
Preservation of bioavailability of ingredients and lack of drug-drug interactions in a novel five-ingredient polypill (polycap): a five-arm phase I crossover trial in healthy volunteers. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2010, Volume: 10, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Antihypertensive Agents; Area Under Curve; Aspirin; Atenolol; Biological Availability; Capsules; Cardiovascular Diseases; Chromatography, Liquid; Cross-Over Studies; Drug Combinations; Drug Interactions; Humans; Hydrochlorothiazide; Hypolipidemic Agents; Male; Middle Aged; Platelet Aggregation Inhibitors; Ramipril; Risk Factors; Simvastatin; Tandem Mass Spectrometry; Young Adult	2010
Effects of valsartan or ramipril addition to amlodipine/hydrochlorothiazide combination on left ventricular mass in diabetic hypertensive patients with left ventricular hypertrophy. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:8 Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Ramipril; Tetrazoles; Valine; Valsartan	2012
Comparison of risk factor reduction and tolerability of a full-dose polypill (with potassium) versus low-dose polypill (polycap) in individuals at high risk of cardiovascular diseases: the Second Indian Polycap Study (TIPS-2) investigators. Circulation. Cardiovascular quality and outcomes, 2012, Jul-01, Volume: 5, Issue:4 Topics: Administration, Oral; Aged; Analysis of Variance; Antihypertensive Agents; Aspirin; Atenolol; Biomarkers; Blood Pressure; Capsules; Cardiovascular Diseases; Cholesterol, LDL; Creatinine; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; India; Male; Middle Aged; Platelet Aggregation Inhibitors; Polypharmacy; Potassium; Ramipril; Risk Assessment; Risk Factors; Simvastatin; Tablets; Time Factors; Treatment Outcome	2012
Efficacy and safety of two ramipril and hydrochlorothiazide fixed-dose combination formulations in adults with stage 1 or stage 2 arterial hypertension evaluated by using ABPM. Clinical therapeutics, 2013, Volume: 35, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brazil; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Ramipril; Time Factors; Treatment Outcome	2013
[Possibilities of rational combination antihypertensive therapy: results of HEMERA international clinical trial]. Terapevticheskii arkhiv, 2013, Volume: 85, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Ramipril; Treatment Outcome; Young Adult	2013
The effect of aliskiren versus ramipril-based treatment on the Ambulatory Arterial Stiffness Index in hypertensive patients. International angiology : a journal of the International Union of Angiology, 2014, Volume: 33, Issue:1 Topics: Adult; Aged; Amides; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Drug Therapy, Combination; Fumarates; Greece; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Predictive Value of Tests; Ramipril; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Time Factors; Treatment Outcome; Vascular Stiffness; Vasodilator Agents	2014
The International Polycap Study-3 (TIPS-3): Design, baseline characteristics and challenges in conduct. American heart journal, 2018, Volume: 206 Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Diuretics; Double-Blind Method; Drug Combinations; Female; Global Health; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Primary Prevention; Ramipril; Retrospective Studies; Simvastatin	2018

Other Studies

35 other study(ies) available for hydrochlorothiazide and ramipril

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The analysis of a multiple-dose, combination-drug clinical trial using response surface methodology. Journal of biopharmaceutical statistics, 1992, Volume: 2, Issue:1 Topics: Analysis of Variance; Antihypertensive Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Models, Biological; Multicenter Studies as Topic; Ramipril; Randomized Controlled Trials as Topic	1992
CE inhibition and natriuresis with ramipril in conscious SHR: different modes of action of loop and thiazide diuretics. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 7 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bridged Bicyclo Compounds; Diuretics; Hydrochlorothiazide; Loop of Henle; Male; Natriuresis; Ramipril; Rats; Rats, Inbred SHR; Sodium Chloride Symporter Inhibitors; Sulfonamides	1987
Synergism of CE-inhibition and diuresis. A study with ramipril, piretanide and HCT in SHR. Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:2-3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Diuresis; Drug Synergism; Heart Rate; Hydrochlorothiazide; Male; Ramipril; Rats; Rats, Inbred SHR; Sodium; Sulfonamides	1987
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Caffeine; Calcium; Calcium Channels; Cell Membrane; Disease Models, Animal; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcoplasmic Reticulum	1993
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats. Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:3 Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Hydralazine; Hydrochlorothiazide; Hypertension; Linear Models; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance	1995
Occupational UVA-induced allergic photodermatitis in a welder due to hydrochlorothiazide and ramipril. Contact dermatitis, 2000, Volume: 43, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Dermatitis, Occupational; Diuretics; Drug Eruptions; Humans; Hydrochlorothiazide; Male; Middle Aged; Photosensitivity Disorders; Ramipril; Sodium Chloride Symporter Inhibitors; Ultraviolet Rays; Welding	2000
A stability-indicating LC method for the simultaneous determination of ramipril and hydrochlorothiazide in dosage forms. Journal of pharmaceutical and biomedical analysis, 2001, Volume: 24, Issue:3 Topics: Chromatography, High Pressure Liquid; Dosage Forms; Hydrochlorothiazide; Pharmaceutical Preparations; Ramipril; Reference Standards; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	2001
Square wave voltammetric determination of the angiotensin-converting enzyme inhibitors cilazapril, quinapril and ramipril in pharmaceutical formulations. Farmaco (Societa chimica italiana : 1989), 2003, Volume: 58, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Drug Combinations; Hydrochlorothiazide; Potentiometry; Quinapril; Ramipril; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tetrahydroisoquinolines	2003
[Therapy of hypertension. Cost conscious prevention of complications]. MMW Fortschritte der Medizin, 2003, Nov-20, Volume: 145, Issue:47 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Cost Savings; Dose-Response Relationship, Drug; Drug Combinations; Drug Costs; Drugs, Generic; Forecasting; Germany; Humans; Hydrochlorothiazide; Hypertension; National Health Programs; Ramipril; Treatment Outcome	2003
[Health care too costly? Saving more than 10 million euros in 2 months!]. MMW Fortschritte der Medizin, 2003, Nov-20, Volume: 145, Issue:47 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cost Savings; Drug Combinations; Drug Costs; Drugs, Generic; Forecasting; Germany; Humans; Hydrochlorothiazide; Hypertension; National Health Programs; Ramipril	2003
[A patient with severe hyperkalaemia -- an emergency after RALES]. Deutsche medizinische Wochenschrift (1946), 2005, Sep-09, Volume: 130, Issue:36 Topics: Acute Kidney Injury; Adrenergic beta-Agonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bradycardia; Diuretics; Drug Therapy, Combination; Electrocardiography; Emergencies; Glucose; Heart Failure; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Male; Mental Disorders; Middle Aged; Prostatic Hyperplasia; Ramipril; Renal Dialysis; Sodium Bicarbonate; Terbutaline	2005
Antihypertensive agents have different ability to modulate arterial pressure and heart rate variability in 2K1C rats. American journal of hypertension, 2006, Volume: 19, Issue:10 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Autonomic Nervous System; Blood Pressure; Cardiovascular System; Heart Rate; Hydrochlorothiazide; Hypertension; Losartan; Male; Ramipril; Rats; Rats, Wistar; Sympathetic Nervous System	2006
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers. International journal of clinical practice, 2006, Volume: 60, Issue:11 Topics: Adolescent; Adult; Amides; Amlodipine; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2006
Effects of commonly administered agents and genetics on nebivolol pharmacokinetics: drug-drug interaction studies. Journal of clinical pharmacology, 2011, Volume: 51, Issue:4 Topics: Adult; Antihypertensive Agents; Benzopyrans; Cytochrome P-450 CYP2D6; Digoxin; Drug Interactions; Ethanolamines; Female; Fluoxetine; Furosemide; Genotype; Humans; Hydrochlorothiazide; Losartan; Male; Middle Aged; Nebivolol; Ramipril; Warfarin; Young Adult	2011
[High blood pressure in the morning]. MMW Fortschritte der Medizin, 2011, Dec-08, Volume: 153, Issue:49-50 Topics: Benzimidazoles; Benzoates; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Delayed-Action Preparations; Drug Combinations; Drug Substitution; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Telmisartan	2011
[Telangiectasia during amlodipine therapy]. Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:3 Topics: Amlodipine; Antihypertensive Agents; Bisoprolol; Calcium Channel Blockers; Drug Substitution; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Ramipril; Telangiectasis	2013
Drugs for treating hypertension. Nursing, 2013, Volume: 43, Issue:8 Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drugs, Generic; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Prescription Drugs; Ramipril; Tetrazoles	2013
Ramipril and hydrochlorothiazide treatment of hypertensive urgency in the ED. The American journal of emergency medicine, 2013, Volume: 31, Issue:10 Topics: Acute Disease; Administration, Oral; Drug Therapy, Combination; Emergency Service, Hospital; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril	2013
Development and validation of bioanalytical method for simultaneous estimation of ramipril and hydrochlorothiazide in human plasma using liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Nov-01, Volume: 970 Topics: Chromatography, Liquid; Drug Stability; Humans; Hydrochlorothiazide; Linear Models; Ramipril; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry	2014
Single-pill combination therapy in the initial treatment of marked hypertension: a propensity-matched analysis. Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Propensity Score; Ramipril; Retrospective Studies; Risk Factors; Telmisartan; Tetrazoles	2015
3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles. Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-10, Volume: 217 Topics: Aspirin; Atenolol; Delayed-Action Preparations; Drug Combinations; Drug Liberation; Excipients; Hydrochlorothiazide; Powder Diffraction; Pravastatin; Printing, Three-Dimensional; Ramipril; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; X-Ray Diffraction	2015
Ramipril + amlodipine and ramipril + hydrochlorothiazide fixed-dose combinations in relation to patient adherence. The Journal of international medical research, 2016, Volume: 44, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Humans; Hungary; Hydrochlorothiazide; Hypertension; Medication Adherence; Ramipril; Retrospective Studies	2016
Biowaiver Eligibility of a Lower Strength Ramipril/Hydrochlorothiazide Immediate Release Tablets Using a New Validated HPLC Analytical Method. Drug research, 2016, Volume: 66, Issue:10 Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drug Liberation; Hydrochlorothiazide; Hydrogen-Ion Concentration; In Vitro Techniques; Ramipril; Tablets; Therapeutic Equivalency	2016
Poly (amidoamine) dendrimer-mediated hybrid formulation for combination therapy of ramipril and hydrochlorothiazide. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jan-01, Volume: 96 Topics: Antihypertensive Agents; Dendrimers; Diuretics; Drug Combinations; Drug Compounding; Drug Liberation; Drug Stability; Hydrochlorothiazide; Ramipril; Solubility	2017
Hansen solubility parameters for assay method optimization of simvastatin, ramipril, atenolol, hydrochlorothiazide and aspirin in human plasma using liquid chromatography with tandem mass spectrometry. Journal of separation science, 2017, Volume: 40, Issue:18 Topics: Aspirin; Atenolol; Chromatography, Liquid; Humans; Hydrochlorothiazide; Ramipril; Reproducibility of Results; Simvastatin; Solubility; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2017
A comparative study between hot-melt extrusion and spray-drying for the manufacture of anti-hypertension compatible monolithic fixed-dose combination products. International journal of pharmaceutics, 2018, Jul-10, Volume: 545, Issue:1-2 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calorimetry, Differential Scanning; Crystallography, X-Ray; Diuretics; Drug Carriers; Drug Combinations; Drug Compounding; Drug Liberation; Drug Stability; Hot Temperature; Hydrochlorothiazide; Kinetics; Microscopy, Electron, Scanning; Particle Size; Plasticizers; Polyethylene Glycols; Polyvinyls; Powder Diffraction; Pyrrolidines; Ramipril; Solubility; Surface Properties; Technology, Pharmaceutical; Vinyl Compounds	2018
Challenges in Simultaneous Determination of Hydrochlorothiazide and Ramipril in Human Plasma: Application to a Bioequivalence Study. Journal of chromatographic science, 2018, Nov-01, Volume: 56, Issue:10 Topics: Chromatography, Liquid; Humans; Hydrochlorothiazide; Limit of Detection; Linear Models; Ramipril; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency	2018
Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid: A Pharmacokinetic Assessment of Central Nervous System Adverse Effects. Pharmacology, 2018, Volume: 102, Issue:3-4 Topics: Aged; Antihypertensive Agents; Blood-Brain Barrier; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Ramipril	2018
Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro. Skin pharmacology and physiology, 2019, Volume: 32, Issue:3 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cell Line; Cell Movement; Diuretics; Fibroblasts; Humans; Hydrochlorothiazide; Keratinocytes; Metoprolol; Ramipril; Tetrazoles; Wound Healing	2019
Analysis of quinary therapy targeting multiple cardiovascular diseases using UV spectrophotometry and chemometric tools. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Sep-05, Volume: 238 Topics: Algorithms; Aspirin; Atenolol; Capsules; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Least-Squares Analysis; Ramipril; Simvastatin; Spectrophotometry, Ultraviolet	2020