hydrochlorothiazide and pyrazines

hydrochlorothiazide has been researched along with pyrazines in 153 studies

Research

Studies (153)

Timeframe	Studies, this research(%)	All Research%
pre-1990	147 (96.08)	18.7374
1990's	5 (3.27)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (0.65)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kanto, J; Lammintausta, R; Mäntylä, R	2
Mikkelsen, E; Pedersen, OL	2
Lumholtz, IB	1
Bonaduce, D; D'Ascia, C; Ferrara, N; Petretta, M; Rengo, F; Saccá, L; Trimarco, B	1
Lederballe Pedersen, O	1
Salvatore, C; Schena, FP; Vox, E	1
Castenfors, H	2
Amadeo, A; Currò, F; de Pasquale, C	1
Overlack, A; Stumpe, KO	1
Evsikov, EM; Kharchenko, VI; Sidorenko, BA	1
Eisalo, A; Kohvakka, A; Manninen, V	1
Bochner, F; McLaran, CJ; Whiting, GF	1
Ambrosioni, E; Magnani, B; Melandri, G; Pasetti, L; Tartagni, F	1
Bergis, K	1
Aroldi, A; Brancaccio, D; Cantaluppi, A; Cecchettin, M; Galmozzi, C; Graziani, G; Mioni, G; Ponticelli, C; Surian, M	1
Bernardi, P; Bobba, P; Croce, L; Dalla Torre, M; Di Benedetto, A; Galassi, A; Lombardo, M; Masacci, E; Montemartini, C; Mussari, A; Ricciardi, S; Santucci, F	1
Dewailly, P; Heim, J; Jaillard, J	1
Chappin, JJ; Henquet, JW; Hintzen, AH; Slagboom, G	1
Alberti, E; Alessi, A; Antognetti, R; Baraldini, L; Bastagli, L; Bellomo, G; Bernardi, P; Buscarini, L; Camarri, E; Camerini, F; Cazzin, R; Dal Canton, A; De Piccoli, B; Del Favero, A; Fontana, G; Forattini, C; Furlanello, F; Giorgi-Pierfranceschi, D; Lechi, A; Lenzi, S; Malamani, V; Migone, L; Nava, S; Pallumeri, E; Passeri, M; Pecoraro, F; Perin, S; Piccolo, E; Scardi, S; Scarpioni, L; Vergara, G	1
Benvenuti, C; Sanguigni, D	1
Baumann, JC; Braun, HD	1
Brailovsky, D	1
Agabiti-Rosei, E; Alicandri, C; Ambrosioni, E; Magnani, B; Miele, N; Muiesan, G	1
Bielecki, A; Piwowarska, W	1
Burge, PS; Montuschi, E	1
Danĕková, H; Dzúrik, R; Fedelesová, V; Hlavatá, E	1
Adornato, E; Tassone, F	1
Bianchi Porre, G; Lazzaroni, M; Petrillo, M	1
Bergström, J	1
Cleres-Kaiser, I	1
Cohen, L; Kitzes, R; Rosenfeld, J	1
Sitprija, V; Stianrapapongs, P	1
Giles, RE; Halterman, TJ; Howe, BB; Johnston, PA; Kau, ST; Leszczynska, K; Li, JH; Schwartz, JA; Yochim, CL; Zuzack, JS	1
Lindsay, RM; Spence, JD; Wong, DG	1
Brachfeld, J; Itskovitz, H; Lunn, JA; Maxwell, MH; Moser, M; Zawada, ET	1
Larochelle, P; Logan, AG	1
Alon, U; Chan, JC	2
Dzúrik, R; Dzúriková, V; Krechnáková, A; Szalayová, V	1
Ferrara, LA; Gagliardi, R; Mancini, M; Scillitani, A; Strazzullo, P	1
Breckenridge, AM; Dollery, CT; George, CF	1
Gilly, R; Herne, N; Le Gall, F; Michaud, J; Roux, M	1
Hitzenberger, G	1
Bartelheimer, HK; von Bruchhausen, F	1
Nash, DT	1
Ilett, KF; Lockett, MF	1
Degaute, JP; Demanet, JC; Fichefet, JP; Hubert, C; Paduart, P	1
Gerbaux, A; Hiltgen, M; Renais, J; Scebat, L	1
McCoubrie, M; Snaith, RP	1
Hintzen, AH	1
Bertrand, ME; Warembourg, H	1
Demanet, JC; Hubert, C; Sevens-Rocmans, C	1
Sanna, GP	1
Kennedy, RD; MacFarlane, JP	1
Bertrand, ME; Ginestet, A; Warembourg, H	1
Cox, JR; Porthouse, A	1
Blatrix, C	1
Falase, AO; Salako, LA	1
Naidoo, DN; Seedat, YK	1
Goulding, A; Irvine, RO; Jukes, C	1
Antcliff, AC; Beevers, DG; Hamilton, M; Harpur, JE	1
Meyer, P; Milliez, P	1
Koshikawa, S; Yamada, T; Yoshida, A	1
Irvine, RO; McKean, WI	1
Koshikawa, S; Sasaoka, T	1
Savoie, L; Selye, H; Somogyi, A	1
Reynolds, TB; Yamada, S	1
Cragoe, EJ; Jones, JH; Mason, JW; Shepard, KL; Woltersdorf, OW	1
Cragoe, EJ; Holtz, WJ; Jones, JH	1
Freis, ED; Gombos, EA; Moghadam, A	1
Glitzer, MS; Steelman, SL	1
Baer, JE; Jones, CB; Russo, HF; Spitzer, SA	1
Franz, IW	1
Albertazzi, A; Cappelli, P; Del Rosso, G; Di Paolo, B; Di Vito, R; Palmieri, PF; Spisni, C	1
Jaffey, L; Martin, A	1
Auvinen, J; Gordin, A; Saraste, K; Seppälä, T; Tarkiainen, A	1
Banderali, G; Carnovali, M; Crespi, E; Missaglia, A; Ponti, GB	1
Hilewitz, H; Rogel, S; Weinstein, M	1
Griffing, GT; Melby, JC	1
Kremer, D	1
Albanesi, FM; Cantarelli, EL; da Cunha, GP; Wajngarten, M	1
Bolzano, K; Krempler, F; Sandhofer, F	1
Lehtonen, A; Lindroos, M	1
Dean, S; Spencer-Mills, L	1
Thomas, JP; Thomson, WH	1
Hutchinson, CE; Jong, M; Matthews, K; Zalin, AM	1
Borland, C; Davison, W; Millson, D; Murphy, P	1
Eastell, R; Edmonds, CJ	1
Barr, J; Chan, L; Maronde, RF; Spencer, CA; Vlachakis, ND	1
Cabili, S; Ophir, J; Ophir, O	1
Brdová, L; Strec, V; Valusková, H	1
Currie, WJ; Isitt, VL; VandenBurg, MJ; Young, JH	1
Arr, SM; Wight, L; Woollard, ML; Young, JH	1
Alon, U; Chan, JC; Costanzo, LS	1
Dige-Petersen, H; Giese, J; Ibsen, H; Leth, A; Nielsen, MD; Rasmussen, S; Svendsen, UG	1
Browne, R; Hill, K; Leppla, D; Pak, CY	1
Obel, AO	1
Schneider, H	1
Ferrara, LA; Galletti, F; Siani, A; Strazzullo, P	1
Bentivoglio, M; Corea, L; Verdecchia, P	1
Galli, F; Piazza, V; Salvadeo, A; Segagni, S; Villa, G	1
Agrawal, N; Akdamar, K; Ertan, A; McMahon, FG; Ryan, JR	1
Cooper, WD; Currie, WJ; Vandenburg, MJ	1
Morse, BM; Stern, RS; Strykers, PH	1
Andersson, PO; H-Andersen, H; Hagman, A; Henning, R	1
Knauf, H; Steim, H	1
Gould, BA; Hornung, RS; Kieso, H; Raftery, EB	2
Arr, S; Parry, EE; Tait, D	1
Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND	1
Mor, R; Pitlik, S; Rosenfeld, JB	1
Brown, JL; Chrysant, SG; Hagstrom, D	1
van Soeren, F	1
Burns, DG; Pittaway, D	1
Pittaway, D	1
Andersson, PO; Henning, R; Karlberg, BE; Lins, LE; Nilsson, OR; Odar-Cederlöf, I; Tolagen, K	1
Gillies, A; Morgan, TO; Myers, JB; Waga, S	1
Hwang, IK; Moncloa, F; Muccilli, AC	1
Huikko, M; Varjoranta, K; Viherkoski, M	1
Leary, WP; Reyes, AJ	1
Nordlie, KE; Søiland, C	1
Ballo, M; Cospite, M; Ferrara, F; Lo Presti, T; Meli, F; Milio, G; Raimondi, F	1
El Mahadi Bella, M; El Zein, O; Khalil, SI	1
Campbell, N; Fernandez, PG; Galway, AB; Gill, V; Granter-Button, S; Kim, BK; MacDonald, J; Sharma, JN; Snedden, W	1
Grimshaw, JJ; Jaffé, G; Vallé-Jones, JC; Warnock, JM	1
Bjaeldager, P; Garsdal, P; Kampmann, JP; Svendsen, TL	1
Salonen, JT; Ylitalo, P	1
Della Marchina, MM; Renzi, G; Serofilli, S	1
Boehringer, K; Meier, A; Mordasini, R; Riesen, W; Schiffl, H; Weidmann, P	1
Aroldi, A; Colussi, G; D'Angelo, A; Fabris, A; Graziani, G; Mandressi, A; Maschio, G; Minetti, L; Pagano, F; Ponticelli, C; Rocco, F; Surian, M; Tasca, A; Tessitore, N; Trinchieri, A	1
Enenkel, W; Nobis, H; Pollak, H; Prachar, H	1
Tarssanen, L	1
Albanesi Filho, FM; Brandão, AP; Oigman, W	1
Pedersen, TR	1
Desai, M; Dotson, R; Rutledge, R; Watthey, JW	1
Frewin, DB; Penhall, RK	1
Alcazar, JM; Diaz, VP; Jarillo, MD; Millet, VG; Rodicio, JL; Ruilope, L	1
Rosenfeld, JB	1
Lye, MD; Wan, HH	1
Okrasinski, H	1
Huikko, M; Rossi, M; Tarssanen, L	1
Beyer, KH; Chambers, CE; Demers, LM; Passananti, GT; Vesell, ES	1
Beyer, KH; Gelarden, RT; Knutson, DW; Vary, JE; Vesell, ES; Ward, TD	1
A-Rahim, YI; Beyer, KH; Vesell, ES	1
Beyer, KH; Follansbee, MH; Griffith, JW; Vesell, ES	1
Arafat, T; Idkaidek, N	1

Reviews

1 review(s) available for hydrochlorothiazide and pyrazines

Article	Year
[Importance of the continuity of anti-hypertension treatment in prevention of ischemic cardiovascular diseases: preliminary note. Controlled study of hypertensive patients treated with amiloride associated with hydrochlorothiazide and chlorthalidone]. Minerva medica, 1978, Jun-23, Volume: 69, Issue:31 Topics: Adult; Aged; Amiloride; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines	1978

Article

Year

[Importance of the continuity of anti-hypertension treatment in prevention of ischemic cardiovascular diseases: preliminary note. Controlled study of hypertensive patients treated with amiloride associated with hydrochlorothiazide and chlorthalidone].

Minerva medica, 1978, Jun-23, Volume: 69, Issue:31

Topics: Adult; Aged; Amiloride; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines

1978

Trials

60 trial(s) available for hydrochlorothiazide and pyrazines

Article	Year
Urinary electrolyte profiles after amiloride, hydrochlorthiazide and the combination. The Journal of international medical research, 1978, Volume: 6, Issue:5 Topics: Adolescent; Adult; Amiloride; Chlorides; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Male; Placebos; Potassium; Pyrazines; Sodium; Urination	1978
Beta-blockers and uric-acid excretion. Lancet (London, England), 1978, Nov-25, Volume: 2, Issue:8100 Topics: Amiloride; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol; Uric Acid	1978
[Treatment of mild to moderate essential arterial hypertension with timolol alone and in combination with hydrochlorothiazide + amiloride. A multicenter, double-blind, cross-over study]. Ugeskrift for laeger, 1977, Aug-01, Volume: 139, Issue:31 Topics: Amiloride; Clinical Trials as Topic; Creatinine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Placebos; Potassium; Propanolamines; Pyrazines; Timolol	1977
[Effects of a potassium-sparing diuretic in cardiac edema and ascitic cirrhosis]. La Clinica terapeutica, 1977, Sep-15, Volume: 82, Issue:5 Topics: Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Edema; Female; Heart Diseases; Humans; Hydrochlorothiazide; Liver Cirrhosis; Male; Middle Aged; Pyrazines	1977
Long term effect of timolol and hydrochlorothiazide, or hydrochlorothiazide and amiloride, in essential hypertension. European journal of clinical pharmacology, 1977, Oct-14, Volume: 12, Issue:2 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pulse; Pyrazines; Time Factors; Timolol	1977
[Antihypertensive effect of a fixed beta-receptor blockader-diuretic combination during a single daily administration]. Die Medizinische Welt, 1978, Sep-29, Volume: 29, Issue:39 Topics: Adult; Amiloride; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Placebos; Propanolamines; Pyrazines; Timolol	1978
[Therapeutic use of amiloride and its combinations with hydrochlorothiazide and furosemide in chronic circulatory insufficiency]. Kardiologiia, 1978, Volume: 18, Issue:11 Topics: Adult; Aged; Amiloride; Cardiovascular Diseases; Chronic Disease; Clinical Trials as Topic; Diuresis; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Furosemide; Humans; Hydrochlorothiazide; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Time Factors	1978
Maintenance of potassium balance during diuretic therapy. Acta medica Scandinavica, 1979, Volume: 205, Issue:4 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Spironolactone; Triamterene	1979
Individual factors influencing the response to a beta-adrenergic blocking agent given alone and in combination with a diuretic on arterial hypertension. European journal of clinical pharmacology, 1979, Volume: 16, Issue:5 Topics: Adult; Aging; Amiloride; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Time Factors; Timolol	1979
Renin-aldosterone system and urinary electrolytes after amiloride, hydrochlorothiazide and the combination. International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:11 Topics: Adolescent; Adult; Aldosterone; Amiloride; Drug Combinations; Electrolytes; Female; Humans; Hydrochlorothiazide; Male; Pyrazines; Renin; Time Factors	1978
[Potassium-saving saluretic treatment of hypertension and edematous heart decompensation with Moduretik]. ZFA. Zeitschrift fur Allgemeinmedizin, 1976, Jun-30, Volume: 52, Issue:18 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Edema, Cardiac; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines	1976
The use of timolol maleate alone and with diuretic in the treatment of essential hypertension. Acta clinica Belgica, 1976, Volume: 31, Issue:5 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Placebos; Potassium; Propanolamines; Pyrazines; Timolol	1976
Evaluation of the effect of timolol alone and in combination with hydrochlorothiazide and amiloride in the treatment of mild to moderate arterial hypertension: a double-blind, controlled study. Clinical science and molecular medicine. Supplement, 1976, Volume: 3 Topics: Adult; Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol	1976
[Letter: Ascrtogenicliver cirrhosis. Effect of amiloride on water-electrolytemetabolsim]. La Nouvelle presse medicale, 1975, Apr-05, Volume: 4, Issue:14 Topics: Amiloride; Ascites; Chlorides; Clinical Trials as Topic; Furosemide; Humans; Hydrochlorothiazide; Hypokalemia; Hyponatremia; Liver Cirrhosis; Pyrazines; Water-Electrolyte Balance	1975
The effect of hydrochlorothiazide and amiloride administered together on muscle electrolytes in normal subjects. Acta medica Scandinavica, 1975, Volume: 197, Issue:5 Topics: Adult; Amiloride; Biopsy; Chlorides; Clinical Trials as Topic; Drug Interactions; Humans; Hydrochlorothiazide; Magnesium; Muscles; Potassium; Pyrazines; Sodium; Water-Electrolyte Balance	1975
[Treatment of cardiac and hepatic edemas using the potassium-sparing diuretic Moduretic]. Die Medizinische Welt, 1975, Apr-18, Volume: 26, Issue:16 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Edema; Female; Heart Diseases; Humans; Hydrochlorothiazide; Liver Diseases; Male; Middle Aged; Pyrazines	1975
[Effect of combined treatment with hydrochlorothiazide and amiloride on serum and urinary potassium]. Harefuah, 1975, Nov-02, Volume: 89, Issue:9 Topics: Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Heart Failure; Humans; Hydrochlorothiazide; Hypokalemia; Potassium; Pyrazines	1975
Effects of triamterene and amiloride on urinary sediment in hypertensive patients taking hydrochlorothiazide. Lancet (London, England), 1985, Jul-13, Volume: 2, Issue:8446 Topics: Amiloride; Clinical Trials as Topic; Crystallization; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kidney Calculi; Male; Middle Aged; Nephritis, Interstitial; Pyrazines; Random Allocation; Triamterene	1985
Blood pressure lowering and potassium conservation by triamterene-hydrochlorothiazide and amiloride-hydrochlorothiazide in hypertension. Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:1 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Triamterene	1985
Hydrochlorothiazide-amiloride versus hydrochlorothiazide alone for essential hypertension: effects on blood pressure and serum potassium level. Canadian Medical Association journal, 1985, Apr-01, Volume: 132, Issue:7 Topics: Adolescent; Adult; Age Factors; Aged; Amiloride; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pulse; Pyrazines; Random Allocation	1985
Cross-over study of muzolimine and hydrochlorothiazide-amiloride in hypertensive patients. European journal of clinical pharmacology, 1985, Volume: 28, Issue:3 Topics: Adult; Amiloride; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Muzolimine; Potassium; Pyrazines; Pyrazoles	1985
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia. Lancet (London, England), 1973, Dec-08, Volume: 2, Issue:7841 Topics: Adult; Aged; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Pyrazines; Sodium; Spironolactone; Time Factors; Urea	1973
[Effect of amiloride on potassium loss induced by hydrochlorothiazide]. La Nouvelle presse medicale, 1974, Sep-21, Volume: 3, Issue:31 Topics: Amiloride; Chlorides; Diuresis; Drug Interactions; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Hypokalemia; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Statistics as Topic	1974
The effects of amiloride during diuretic therapy in elderly subjects. Age and ageing, 1972, Volume: 1, Issue:2 Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinations; Edema; Female; Humans; Hydrochlorothiazide; Hypokalemia; Male; Potassium; Pyrazines; Sodium; Urea; Uric Acid	1972
[Treatment of cardiac edema with a new diuretic (combination of amiloride hydrochlorate and hydrochlorothiazide)]. Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1974, Volume: 19, Issue:2 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Diuretics; Drug Combinations; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Sodium	1974
Amiloride hydrochloride combined with hydrochlorothiazide in the control of hypertension and plasma potassium levels. The British journal of clinical practice, 1972, Volume: 26, Issue:9 Topics: Alanine Transaminase; Amiloride; Aspartate Aminotransferases; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Pyrazines; Urea; Uric Acid	1972
[Treatment of the hypertensive patient. Value of Amiloride during saldiuretic treatment]. La Nouvelle presse medicale, 1972, Sep-16, Volume: 1, Issue:32 Topics: Adult; Amiloride; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kidney Function Tests; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Spironolactone; Water-Electrolyte Balance	1972
Amiloride (MK-870), a new antikaluretic diuretic. Comparison to other antikaluretic diuretics in patients with liver disease and ascites. Gastroenterology, 1970, Volume: 59, Issue:6 Topics: Acid-Base Equilibrium; Amidines; Ascites; Autopsy; Carcinoma; Diuretics; Ethacrynic Acid; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Hyperkalemia; Liver Cirrhosis; Liver Neoplasms; Pyrazines; Spironolactone; Triamterene; Water-Electrolyte Balance	1970
A controlled study of the antihypertensive effect of carteolol, a new beta-adrenergic receptor blocking drug, in combination with hydrochlorothiazide and amiloride. European journal of clinical pharmacology, 1981, Volume: 19, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Carteolol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines	1981
The therapeutic use of a new potassium-sparing diuretic, amiloride, and a converting enzyme inhibitor, MK-421, in preventing hypokalemia associated with primary and secondary hyperaldosteronism. Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:6 Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Dipeptides; Diuretics; Electrolytes; Enalapril; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypokalemia; Male; Middle Aged; Pyrazines; Renin	1983
[Treatment of cardiac failure with diuretics. A double-blind study comparing a fixed combination of hydrochlorothiazide/amiloride and furosemide plus potassium substitution]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1983, May-20, Volume: 103, Issue:14 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Middle Aged; Potassium; Pyrazines	1983
[Treatment of arterial hypertension with a combination of hydrochlorothiazide and hydrochloride amiloride]. Arquivos brasileiros de cardiologia, 1983, Volume: 40, Issue:5 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Sodium	1983
[A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension]. Acta medica Austriaca, 1984, Volume: 11, Issue:2 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Posture; Pulse; Pyrazines; Urea; Uric Acid	1984
Timolol and a hydrochlorothiazide-amiloride combination in the treatment of essential hypertension in young and middle-aged patients: a comparative study with once-daily administration. International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:12 Topics: Adult; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Timolol	1984
Hydrochlorothiazide in combination with potassium-sparing agents in the treatment of hypertension. Current medical research and opinion, 1984, Volume: 9, Issue:5 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Random Allocation; Triamterene	1984
Comparison of thiazides and amiloride in treatment of moderate hypertension. British medical journal (Clinical research ed.), 1983, Jun-25, Volume: 286, Issue:6383 Topics: Adult; Aged; Amiloride; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Metoprolol; Middle Aged; Potassium; Pyrazines	1983
Comparison of a fixed ratio combination of hydrochlorothiazide, amiloride and timolol ('Moducren') given once versus twice daily in mild to moderate hypertension. Pharmatherapeutica, 1984, Volume: 4, Issue:1 Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Administration Schedule; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Time Factors; Timolol	1984
Efficacy and tolerance of a fixed ratio combination of hydrochlorothiazide, amiloride and timolol, taken before or after food, in the treatment of hypertension. Current medical research and opinion, 1984, Volume: 9, Issue:4 Topics: Adult; Aged; Amiloride; Drug Combinations; Female; Food; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Timolol	1984
Effects of amiloride on plasma and total body potassium, blood pressure, and the renin-angiotensin-aldosterone system in thiazide-treated hypertensive patients. Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:4 Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Renin-Angiotensin System	1983
A comparison of timolol plus hydrochlorothiazide plus amiloride and methyldopa in essential hypertension in Black Africans. Tropical and geographical medicine, 1983, Volume: 35, Issue:3 Topics: Adult; Amiloride; Antihypertensive Agents; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Kenya; Male; Methyldopa; Middle Aged; Pyrazines; Random Allocation; Timolol	1983
Long term treatment with tienilic acid or thiazides: comparison of antihypertensive and metabolic effects. European journal of clinical pharmacology, 1983, Volume: 25, Issue:6 Topics: Adult; Amiloride; Blood Pressure; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Liver Function Tests; Male; Middle Aged; Potassium; Pyrazines; Random Allocation; Ticrynafen; Uric Acid	1983
Potassium sparing by amiloride during thiazide therapy in hypertension. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:2 Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines	1984
A general practice study of timolol/hydrochlorothiazide/amiloride ('Moducren'), a new therapy for hypertension, and the doctor's influence on management. Pharmatherapeutica, 1983, Volume: 3, Issue:5 Topics: Adult; Aged; Amiloride; Blood Pressure; Drug Combinations; Family Practice; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Propanolamines; Pyrazines; Timolol	1983
Response of thiazide-induced hypokalemia to amiloride. JAMA, 1983, Jan-14, Volume: 249, Issue:2 Topics: Aldosterone; Amiloride; Bicarbonates; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Potassium; Pyrazines	1983
The antihypertensive and biochemical effects of hydrochlorothiazide/amiloride (Moduretic) versus chlorthalidone. The Journal of international medical research, 1980, Volume: 8, Issue:2 Topics: Adult; Aged; Amiloride; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Pyrazines	1980
Combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A multicentre trial. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, May-17, Volume: 57, Issue:20 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Maleates; Middle Aged; Placebos; Potassium; Propanolamines; Pyrazines; Timolol; Urate Oxidase	1980
Evaluation of a fixed combination of timolol maleate, hydrochlorothiazide and amiloride hydrochloride in the treatment of hypertension: A long-term multicentre trial. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Aug-09, Volume: 58, Issue:6 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diastole; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Potassium; Propanolamines; Pulse; Pyrazines; Systole; Time Factors; Timolol; Uric Acid	1980
Timolol and hydrochlorothiazide-amiloride in primary hypertension. Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:6 Topics: Adult; Amiloride; Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Renin; Timolol	1980
Effect of tienilic acid and amiloride in healthy volunteers and in hypertensives with normal renal function. British journal of clinical pharmacology, 1980, Volume: 10, Issue:4 Topics: Adolescent; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Electrolytes; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Middle Aged; Pyrazines; Ticrynafen; Uric Acid	1980
Multiclinic evaluation of the antihypertensive effect of a methyldopa, hydrochlorothiazine, and amiloride combination. Clinical therapeutics, 1980, Volume: 3, Issue:3 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Pyrazines; Random Allocation; Time Factors	1980
Multiclinic comparison of amiloride, hydrochlorothiazide, and hydrochlorothiazide plus amiloride in essential hypertension. Multicenter Diuretic Cooperative Study Group. Archives of internal medicine, 1981, Volume: 141, Issue:4 Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines	1981
The effect of amiloride/hydrochlorothiazide combination vs furosemide plus potassium supplementation in the treatment of oedema of cardiac origin. Annals of clinical research, 1981, Volume: 13, Issue:1 Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Edema, Cardiac; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium Chloride; Pyrazines	1981
Antihypertensive and metabolic effects of a combination of hydrochlorothiazide and amiloride. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Sep-05, Volume: 60, Issue:10 Topics: Adult; Aged; Amiloride; Blood Proteins; Blood Urea Nitrogen; Cholesterol; Clinical Trials as Topic; Creatinine; Drug Combinations; Electrolytes; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Time Factors	1981
[Moduretic in the treatment of cardiac failure]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1981, Jun-10, Volume: 101, Issue:16 Topics: Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Female; Follow-Up Studies; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Pyrazines	1981
A double-blind, crossover study of acebutolol and hydrochlorothiazide/amiloride diuretic in Sudanese patients with essential hypertension. Current medical research and opinion, 1982, Volume: 8, Issue:1 Topics: Acebutolol; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Pulse; Pyrazines; Sudan	1982
Potassium conservation with amiloride/hydrochlorothiazide ("Moduret') in thiazide-induced hypokalaemia in hypertension. Current medical research and opinion, 1982, Volume: 8, Issue:2 Topics: Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Potassium; Pyrazines	1982
Antihypertensive, saluretic and hypokalaemic effects of cyclothiazide in comparison with hydrochlorthiazide with amiloride supplement. European journal of clinical pharmacology, 1982, Volume: 22, Issue:6 Topics: Adult; Amiloride; Antihypertensive Agents; Benzothiadiazines; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Middle Aged; Natriuresis; Pyrazines	1982
[The effect of hydrochlorothiazide/amiloride alone or in combination with alpha-methyldopa on serum lipoproteins]. Schweizerische medizinische Wochenschrift, 1981, Apr-11, Volume: 111, Issue:15 Topics: Adult; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Methyldopa; Pyrazines	1981
[Hypertension treated with hydrochlorothiazide/amilorid and timolol maleate]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1980, Jan-30, Volume: 100, Issue:3 Topics: Adult; Amiloride; Blood Pressure; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Propanolamines; Pyrazines; Timolol	1980
Effects of pyrazinoylguanidine on the glucose-fatty acid cycle in normal subjects and patients with non-insulin-dependent diabetes mellitus. Journal of clinical pharmacology, 1993, Volume: 33, Issue:9 Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Down-Regulation; Fatty Acids; Female; Glucose Tolerance Test; Guanidines; Humans; Hydrochlorothiazide; Insulin; Male; Middle Aged; Pyrazines; Uremia	1993

Other Studies

92 other study(ies) available for hydrochlorothiazide and pyrazines

Article	Year
[Drug information. Therapeutic main group: diuretics. 13. Combination preparations with potassium-preserving diuretics: amiloride and hydrochlorothiazide (Moduretic)]. Sygeplejersken, 1979, Jan-24, Volume: 79, Issue:4 Topics: Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Potassium; Pyrazines	1979
Potassium sparing effect of amiloride in patients receiving diuretics: a quantitative study. Acta cardiologica, 1979, Volume: 34, Issue:4 Topics: Adult; Amiloride; Body Weight; Diuretics; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Pyrazines; Sodium; Time Factors	1979
Severe hyperkalaemia with Moduretic. The Medical journal of Australia, 1979, May-05, Volume: 1, Issue:9 Topics: Aged; Amiloride; Arrhythmias, Cardiac; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Middle Aged; Pyrazines	1979
Total body potassium and long-term treatment with amiloride HCL and/or hydrochlorothiazide. International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:10 Topics: Amiloride; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Potassium; Pyrazines; Time Factors	1979
[Results of a field study with Moducrin in 12596 hypertensive patients]. Die Medizinische Welt, 1979, Nov-16, Volume: 30, Issue:46 Topics: Amiloride; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol	1979
Thiazide diuretics in renal hypercalciuria. Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1979, Volume: 16 Topics: Adult; Amiloride; Calcium; Diuretics; Humans; Hydrochlorothiazide; Parathyroid Glands; Pyrazines; Sodium Chloride Symporter Inhibitors; Urinary Bladder Calculi	1979
[The combination of hydrochlorothiazide, amiloride and alpha-methyldopa in the treatment of arterial hypertension. Clinical evaluation of a multicentric study]. Minerva cardioangiologica, 1979, Volume: 27, Issue:12 Topics: Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines	1979
[Hyperkalemia caused by hyporeninism: role of the hydrochlorothiazide-amiloride combination]. Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1977, Volume: 22, Issue:10 Topics: Aged; Aldosterone; Amiloride; Diabetes Complications; Female; Heart Failure; Humans; Hydrochlorothiazide; Hyperkalemia; Pyrazines; Renin	1977
Concomitant administration of timolol and hydrochlorothiazide/amiloride in hypertensive patients. Results of a titration study. The Journal of international medical research, 1978, Volume: 6, Issue:3 Topics: Adult; Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol	1978
[Long-term treatment of hypertension with the combination of hydrochlorothiazine and amiloride. Results of a multi-center study of 277 patients]. Minerva cardioangiologica, 1978, Volume: 26, Issue:11 Topics: Adult; Aged; Amiloride; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines	1978
[Comparison of spironolactone and amiloride combined with hydrochlorothiazide in the treatment of slight or moderate hypertension]. La Clinica terapeutica, 1978, Oct-15, Volume: 87, Issue:1 Topics: Amiloride; Blood Glucose; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Spironolactone; Uric Acid	1978
[Moduretic in ambulatory treatment of hypertension]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1977, Aug-08, Volume: 32, Issue:32 Topics: Adult; Amiloride; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines	1977
Long-term effects of an amiloride/hydrochlorothiazide combination ('Moduretic') on electrolyte balance. Current medical research and opinion, 1976, Volume: 4, Issue:4 Topics: Adult; Aged; Amiloride; Drug Combinations; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines	1976
[Treatment of oedematous conditions in combining amilorid and hydrochlorothiazid (author's transl)]. Bratislavske lekarske listy, 1976, Volume: 66, Issue:3 Topics: Amiloride; Drug Therapy, Combination; Edema; Humans; Hydrochlorothiazide; Pyrazines	1976
[Combination of amiloride chlorhydrate and hydrochlorothiazide in the ambulatory treatment of mild and moderate hypertension]. La Clinica terapeutica, 1976, Oct-31, Volume: 79, Issue:2 Topics: Adult; Ambulatory Care; Amiloride; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines	1976
[Comparative clinical investigation of furosemide and moduretic in the treatment of cardiac failure]. Lakartidningen, 1975, Apr-02, Volume: 72, Issue:14 Topics: Aged; Amiloride; Female; Furosemide; Heart Diseases; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Pyrazines	1975
Diuretic effect of combined thiazide and amiloride. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1975, Volume: 58, Issue:4 Topics: Adult; Amiloride; Diuretics; Drug Combinations; Drug Therapy, Combination; Heart Failure; Humans; Hydrochlorothiazide; Middle Aged; Pyrazines	1975
[The connection between Moduretic and diabetes mellitus. A case report]. Lakartidningen, 1975, Jun-18, Volume: 72, Issue:25 Topics: Aged; Amiloride; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide; Pyrazines	1975
Renal and antihypertensive effects of a novel eukalemic diuretic, ICI 207,828. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2 Topics: Amiloride; Animals; Antihypertensive Agents; Bufonidae; Cornea; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Furosemide; Hydrochlorothiazide; In Vitro Techniques; Indomethacin; Kidney; Male; Potassium; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Urinary Bladder	1992
Effects of hydrochlorothiazide and amiloride in renal hypophosphatemic rickets. Pediatrics, 1985, Volume: 75, Issue:4 Topics: Adolescent; Alkaline Phosphatase; Amiloride; Bone and Bones; Calcium; Child; Child, Preschool; Chronic Kidney Disease-Mineral and Bone Disorder; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney; Male; Parathyroid Hormone; Phosphates; Pyrazines; Radiography, Abdominal; Time Factors; Ultrasonography; X Chromosome	1985
[Combination of methyldopa and diuretics in the treatment of hypertensive disease]. Vnitrni lekarstvi, 1985, Volume: 31, Issue:1 Topics: Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines	1985
Hydrochlorothiazide-amiloride in the treatment of congenital nephrogenic diabetes insipidus. American journal of nephrology, 1985, Volume: 5, Issue:1 Topics: Adult; Alkalosis; Amiloride; Body Weight; Child; Diabetes Insipidus; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypokalemia; Kidney Tubules; Male; Pyrazines; Tolmetin	1985
[Clinical study of amiloride hydrochloride, a diuretic with low potassium loss]. La Presse medicale, 1970, Jan-03, Volume: 78, Issue:1 Topics: Arrhythmias, Cardiac; Blood Urea Nitrogen; Cardiac Complexes, Premature; Diuretics; Drug Synergism; Edema; Ethacrynic Acid; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Liver Cirrhosis; Potassium; Pyrazines; Sodium	1970
[Therapy of cardiac edema with a combination of hydrochlorthiazide and amiloride-HCl (author's transl)]. Wiener klinische Wochenschrift, 1973, Dec-28, Volume: 85, Issue:52 Topics: Alkalosis; Diuretics; Drug Combinations; Electrolytes; Heart Failure; Hydrochlorothiazide; Hypokalemia; Long-Term Care; Pyrazines; Sodium	1973
[Changes in electrolyte movements induced by diuretics in isolated adipose tissue]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2 Topics: Adipose Tissue; Biological Transport; Depression, Chemical; Diuretics; Electrolytes; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; In Vitro Techniques; Potassium; Potassium Isotopes; Pyrazines; Sodium; Sodium Isotopes; Triamterene	1968
A clinical study of Co-hydroDiuril a combination of an antikaliuretic (amiloride) and hydrochlorothiazide. Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:9 Topics: Adult; Aged; Amiloride; Blood Pressure; Blood Urea Nitrogen; Body Weight; Diuretics; Drug Combinations; Drug Eruptions; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines; Urinary Incontinence; Vertigo	1972
Adaptation to the natriuretic actions of hydrochlorothiazide, frusemide and amiloride, by rats. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:4 Topics: Adaptation, Physiological; Adrenal Glands; Adrenalectomy; Aldosterone; Amiloride; Animals; Corticosterone; Diuresis; Diuretics; Female; Furosemide; Hydrochlorothiazide; Juxtaglomerular Apparatus; Natriuresis; Potassium; Pyrazines; Rats; Renin; Sodium; Sodium Chloride; Spironolactone; Time Factors	1972
Tolerance and side-effects of the association hydrochlorothiazide-amiloride in long-term treatment of arterial hypertension. Acta clinica Belgica, 1974, Volume: 29, Issue:5 Topics: Adult; Aged; Amiloride; Calcium; Creatinine; Drug Combinations; Drug Tolerance; Humans; Hydrochlorothiazide; Hypercalcemia; Hypertension; Hypocalcemia; Middle Aged; Potassium; Pyrazines; Sodium; Time Factors; Urea; Uric Acid	1974
Antihypertensive drugs and depression. Psychological medicine, 1974, Volume: 4, Issue:4 Topics: Adult; Aged; Antihypertensive Agents; Bethanidine; Chlorthalidone; Depression; Diuretics; Drug Therapy, Combination; Fatigue; Furosemide; Guanethidine; Humans; Hydrochlorothiazide; Methyldopa; Middle Aged; Phenobarbital; Potassium; Pyrazines; Reserpine; Self-Assessment; Sodium Chloride Symporter Inhibitors; Theobromine	1974
Some aspects of the use of Moduretic in the treatment of patients with mild hypertension. Acta cardiologica, 1973, Volume: 28, Issue:3 Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines	1973
[The treatment of cardiac edemas with a new diuretic (combination of amiloride and hydrochlorothiazide)]. Acta cardiologica, 1973, Volume: 28, Issue:3 Topics: Adult; Aged; Amiloride; Diuretics; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Pyrazines	1973
[Comparison of the combination of hydrochlorothiazide and amiloride (Moduretic) and furosemide in the treatment of cardiac edema]. Acta cardiologica, 1973, Volume: 28, Issue:3 Topics: Aged; Amiloride; Diuretics; Drug Combinations; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Pyrazines	1973
Antikaluretic action of amiloride. Acta cardiologica, 1973 Topics: Amiloride; Animals; Calcium; Diuretics; Furosemide; Hydrochlorothiazide; Kidney; Potassium; Pyrazines; Rats; Spironolactone	1973
Effect of amiloride and hydrochlorothiazide on body fluids and electrolytes in geriatric patients with congestive cardiac failure. Gerontologia clinica, 1974, Volume: 16, Issue:1 Topics: Aged; Amiloride; Body Fluids; Diuretics; Electrolytes; Heart Failure; Humans; Hydrochlorothiazide; Potassium; Pyrazines; Radioisotope Dilution Technique; Sodium; Water-Electrolyte Balance	1974
[Diuretic treatment of arterial hypertension. Value of potassium sparing]. Therapeutique (La Semaine des hopitaux), 1972, Volume: 48, Issue:10 Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines	1972
A comparison of moduretic and hydrochlorothiazide in the treatment of hypertension in African patients. East African medical journal, 1973, Volume: 50, Issue:1 Topics: Adult; Aged; Amiloride; Blood Pressure; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium Chloride; Pyrazines; Urea; Uric Acid	1973
Evaluation of amiloride combined with hydrochlorothiazide (Moduretic) in the treatment of hypertension. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Jul-21, Volume: 47, Issue:28 Topics: Adult; Aged; Amiloride; Benzothiadiazines; Diuretics; Drug Combinations; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Propranolol; Pyrazines; Urea; Uremia	1973
Effects of hydrochlorothiazide and amiloride on potassium distribution in skeletal muscle of the rat. Pharmacology, 1973, Volume: 9, Issue:5 Topics: Amiloride; Animals; Body Weight; Chlorides; Diuretics; Extracellular Space; Hydrochlorothiazide; Male; Muscles; Potassium; Pyrazines; Rats; Sodium; Water	1973
Effect of diuretics on energy metabolism. Biochemical pharmacology, 1971, Volume: 20, Issue:8 Topics: Adenosine Triphosphate; Animals; Chlormerodrin; Depression, Chemical; Dinitrophenols; Diuretics; Electron Transport; Ethacrynic Acid; Hydrochlorothiazide; In Vitro Techniques; Ketoglutaric Acids; Kidney; Male; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Polarography; Pyrazines; Rats; Succinates	1971
Evaluation of amiloride combined with hydrochlorothiazide in the treatment of congestive heart failure. The New Zealand medical journal, 1970, Volume: 72, Issue:459 Topics: Aged; Amidines; Body Weight; Diuretics; Drug Synergism; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Pyrazines; Sodium; Time Factors; Urea	1970
Clinical evaluations of a combined application of amiloride (MK-870) and thiazide. Japanese heart journal, 1969, Volume: 10, Issue:4 Topics: Adult; Blood Pressure; Diuretics; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Kidney Function Tests; Liver Cirrhosis; Male; Middle Aged; Nephrotic Syndrome; Potassium; Pyrazines; Sodium	1969
Prevention of stress-induced cardiac necrosis by amiloride. Angiologica, 1969, Volume: 6, Issue:5 Topics: Animals; Diuretics; Ethacrynic Acid; Female; Heart Diseases; Hydrochlorothiazide; Immobilization; Myocardial Infarction; Necrosis; Potassium; Pyrazines; Rats; Stress, Physiological	1969
Pyrazine diuretics. VI. (Pyrazinecarboxamido)guanidines. Journal of medicinal chemistry, 1969, Volume: 12, Issue:2 Topics: Animals; Chlorothiazide; Desoxycorticosterone; Diuresis; Diuretics; Dogs; Guanidines; Hydrochlorothiazide; Methods; Natriuresis; Pyrazines; Rats	1969
Pyrazine diuretics. VII. N-amidino-3-substituted pyrazinecarboxamides. Journal of medicinal chemistry, 1969, Volume: 12, Issue:2 Topics: Animals; Chlorothiazide; Desoxycorticosterone; Diuretics; Hydrochlorothiazide; Pyrazines; Rats	1969
Effects of MK-870 in normal subjects and hypertensive patients. The New England journal of medicine, 1966, Dec-01, Volume: 275, Issue:22 Topics: Adult; Aged; Amidines; Blood Urea Nitrogen; Creatine; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Natriuresis; Potassium; Pyrazines; Sodium; Uric Acid	1966
N-Amidino-3,5-diamino-6-chloropyrazine-carboxamide: an active diuretic in the carboxamide series. Nature, 1966, Oct-08, Volume: 212, Issue:5058 Topics: Adrenalectomy; Aldosterone; Amides; Amidines; Animals; Desoxycorticosterone; Diuretics; Hydrochlorothiazide; Hydrocortisone; Male; Potassium; Pyrazines; Rats; Sodium; Spironolactone; Sulfhydryl Compounds	1966
The potassium-sparing and natriuretic activity of N-amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate (amiloride hydrochloride). The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:2 Topics: Acetazolamide; Adrenalectomy; Amidines; Animals; Chlorides; Chromatography, Paper; Dogs; Female; Fluorescence; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Natriuresis; Organomercury Compounds; Potassium; Potassium Chloride; Pyrazines; Rats; Triamterene	1967
Differential antihypertensive effect of acebutolol and hydrochlorothiazide/amiloride hydrochloride combination on elevated exercise blood pressures in hypertensive patients. The American journal of cardiology, 1980, Volume: 46, Issue:2 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Sodium Chloride Symporter Inhibitors	1980
[Physiopathological basis for a tailored management of essential hypertension]. La Clinica terapeutica, 1981, Feb-28, Volume: 96, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Locomotion; Male; Middle Aged; Potassium; Pyrazines; Renin; Sodium	1981
Malignant hyperkalaemia after amiloride/hydrochlorothiazide treatment. Lancet (London, England), 1981, Jun-06, Volume: 1, Issue:8232 Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Potassium; Pyrazines	1981
[Efficacy of the association of atenolol with an amiloride-hydrochlorothiazide combination in the treatment of persistent arterial hypertension]. La Clinica terapeutica, 1984, Mar-15, Volume: 108, Issue:5 Topics: Adult; Aged; Amiloride; Atenolol; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Retrospective Studies	1984
The effect of single-dose methyldopa and diuretic on BP and left ventricular mass. Archives of internal medicine, 1984, Volume: 144, Issue:8 Topics: Adult; Aged; Amiloride; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines; Stroke Volume; Time Factors	1984
Comparison of thiazides and amiloride in treatment of moderate hypertension. British medical journal (Clinical research ed.), 1983, Aug-27, Volume: 287, Issue:6392 Topics: Amiloride; Blood Glucose; Humans; Hydrochlorothiazide; Hypertension; Pyrazines	1983
Hyponatraemia during treatment with chlorpropamide and Moduretic (amiloride plus hydrochlorothiazide). British medical journal (Clinical research ed.), 1984, Sep-15, Volume: 289, Issue:6446 Topics: Aged; Amiloride; Chlorpropamide; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyponatremia; Male; Middle Aged; Pyrazines	1984
Hyponatraemia and Moduretic (amiloride plus hydrochlorothiazide) British medical journal (Clinical research ed.), 1984, Nov-10, Volume: 289, Issue:6454 Topics: Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines	1984
Hyponatraemia associated with trimethoprim and a diuretic. British medical journal (Clinical research ed.), 1984, Dec-15, Volume: 289, Issue:6459 Topics: Aged; Amiloride; Body Weight; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines; Trimethoprim; Urinary Tract Infections; Urodynamics	1984
Oral potassium chloride and amiloride in hydrochlorothiazide-induced potassium loss. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:4 Topics: Administration, Oral; Adult; Aldosterone; Amiloride; Biological Availability; Creatinine; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Kinetics; Male; Middle Aged; Potassium; Pyrazines; Sodium	1984
[Photosensitivity due to combined hydrochlorothiazide and amiloride]. Harefuah, 1984, Volume: 107, Issue:1-2 Topics: Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Middle Aged; Photosensitivity Disorders; Pyrazines; Ultraviolet Rays	1984
[Combination of carbonated baths with potassium-sparing diuretics]. Bratislavske lekarske listy, 1984, Volume: 82, Issue:3 Topics: Adult; Amiloride; Balneology; Carbonates; Diuresis; Drug Combinations; Humans; Hydrochlorothiazide; Male; Middle Aged; Natriuresis; Potassium; Pyrazines	1984
Additive hypocalciuric effects of amiloride and hydrochlorothiazide in patients treated with calcitriol. Mineral and electrolyte metabolism, 1984, Volume: 10, Issue:6 Topics: Absorption; Adolescent; Adult; Amiloride; Calcitriol; Calcium; Child; Child, Preschool; Diuretics; Drug Interactions; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypophosphatemia, Familial; Male; Pseudohypoparathyroidism; Pyrazines; Rickets; Sodium	1984
Effect of amiloride with or without hydrochlorothiazide on urinary calcium and saturation of calcium salts. The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:5 Topics: Adult; Aged; Amiloride; Calcium; Calcium Oxalate; Calcium Phosphates; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Potassium; Pyrazines	1983
[Current aspects of hypertension treatment. Symposium 10 years Moduretic, Budapest 9-12 June 1983]. ZFA. Zeitschrift fur Allgemeinmedizin, 1983, Sep-30, Volume: 59, Issue:27 Topics: Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Pyrazines	1983
Effects of hydrochlorothiazide combined with amiloride in atenolol-resistant hypertensive patients. International journal of clinical pharmacology research, 1983, Volume: 3, Issue:5 Topics: Adult; Amiloride; Atenolol; Blood Pressure; Drug Combinations; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Pyrazines	1983
Pressure and humoral changes induced by atenolol and hydrochlorothiazide + amiloride, alone and in free combination. A comparative between-patient study. International journal of clinical pharmacology research, 1983, Volume: 3, Issue:5 Topics: Adult; Amiloride; Atenolol; Blood Pressure; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Pyrazines	1983
Mucosal irritant potential of a potassium-sparing diuretic and of wax-matrix potassium chloride. Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:1 Topics: Amiloride; Delayed-Action Preparations; Drug Combinations; Duodenal Ulcer; Endoscopy; Esophageal Diseases; Gastroscopy; Humans; Hydrochlorothiazide; Irritants; Male; Potassium Chloride; Pyrazines; Stomach Ulcer; Ulcer; Waxes	1984
Do elderly patients respond differently to treatment with Moducren? The British journal of clinical practice, 1984, Volume: 38, Issue:3 Topics: Adult; Age Factors; Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Timolol	1984
Hyponatremia induced by a combination of amiloride and hydrochlorothiazide. JAMA, 1984, Jul-20, Volume: 252, Issue:3 Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Pyrazines	1984
[Reliable lowering of blood pressure with one tablet of Moducrin daily (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1980, Jan-25, Volume: 122, Issue:4 Topics: Amiloride; Blood Pressure; Circadian Rhythm; Drug Combinations; Drug Evaluation; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol	1980
[Therapy of hypertension with timolol, hydrochlorothiazide and amiloride]. Fortschritte der Medizin, 1983, Mar-17, Volume: 101, Issue:10 Topics: Amiloride; Humans; Hydrochlorothiazide; Hypertension; Propanolamines; Pyrazines; Timolol	1983
Indomethacin- and Moduretic--induced hyperkalemia. Israel journal of medical sciences, 1983, Volume: 19, Issue:6 Topics: Aged; Amiloride; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Drug Interactions; Female; Heart Failure; Humans; Hydrochlorothiazide; Hyperkalemia; Indomethacin; Pyrazines	1983
Antihypertensive and metabolic effects of hydrochlorothiazide, amiloride-hydrochlorothiazide, and timolol. Journal of clinical pharmacology, 1983, Volume: 23, Issue:4 Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Timolol	1983
[Antihypertensive effects of timolol and of the combination timolol, amiloride and hydrochlorothiazide]. La Clinica terapeutica, 1981, Sep-30, Volume: 98, Issue:6 Topics: Adult; Amiloride; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Renin; Sodium; Timolol	1981
A comparative study of Moducren and Moduretic and their effect on plasma potassium in essential hypertension. The Practitioner, 1982, Volume: 226, Issue:1364 Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Body Weight; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propanolamines; Pyrazines; Random Allocation; Timolol	1982
[Severe hyperkalemia during treatment with Moduretic]. Ugeskrift for laeger, 1982, Apr-12, Volume: 144, Issue:15 Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Pyrazines	1982
[Photodermatitis during treatment with Moduretic]. Ugeskrift for laeger, 1982, Apr-12, Volume: 144, Issue:15 Topics: Adult; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Photosensitivity Disorders; Pyrazines	1982
The effect of a combination of timolol, hydrochlorothiazide and amiloride on 24 hour blood pressure control using ambulatory intra-arterial monitoring. British journal of clinical pharmacology, 1982, Volume: 14, Issue:3 Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Drug Combinations; Humans; Hydrochlorothiazide; Male; Middle Aged; Monitoring, Physiologic; Propanolamines; Pyrazines; Timolol	1982
[Diuretic therapy in the aged. A clinical comparison between two diuretic compounds]. Minerva medica, 1981, Jan-28, Volume: 72, Issue:3 Topics: Aged; Amiloride; Diuretics; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Pyrazines; Quinazolines; Sulfonamides	1981
Prevention of calcium nephrolithiasis with low-dose thiazide, amiloride and allopurinol. The American journal of medicine, 1981, Volume: 71, Issue:4 Topics: Adult; Allopurinol; Amiloride; Calcium; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Pyrazines; Uric Acid	1981
[Moducrin--a new combined preparation in the treatment of hypertension (author's transl)]. Wiener klinische Wochenschrift, 1981, Aug-07, Volume: 93, Issue:15 Topics: Adult; Amiloride; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Prospective Studies; Pyrazines; Timolol	1981
[Hyponatremia associated with diuretic therapy in an elderly patient]. Duodecim; laaketieteellinen aikakauskirja, 1981, Volume: 97, Issue:22 Topics: Aged; Amiloride; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines	1981
[Treatment of arterial hypertension: comparative study of atenolol + chlorthalidone vs. timolol maleate-hydrochlorthiazide-amiloride association]. Arquivos brasileiros de cardiologia, 1981, Volume: 37, Issue:6 Topics: Adult; Aged; Amiloride; Atenolol; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol	1981
Synthesis and diuretic profile of 3-(3-amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine, an amiloride-type diuretic. Journal of medicinal chemistry, 1980, Volume: 23, Issue:6 Topics: Animals; Diuretics; Dogs; Hydrochlorothiazide; Natriuresis; Oxadiazoles; Pyrazines; Rats; Structure-Activity Relationship	1980
Plasma potassium levels in hypertensive patients receiving fixed-combination diuretic therapy. The Medical journal of Australia, 1980, Apr-19, Volume: 1, Issue:8 Topics: Adult; Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Potassium; Pyrazines	1980
A fixed combination of hydrochlorothiazide and amiloride for the treatment of essential hypertension. Clinical therapeutics, 1980, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Amiloride; Blood Chemical Analysis; Blood Pressure; Body Weight; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Male; Middle Aged; Pyrazines; Uric Acid	1980
[Comparative evaluation of the anti-hypertensive effect of moduretic and thiazides]. Schweizerische medizinische Wochenschrift, 1980, Oct-11, Volume: 110, Issue:41 Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines; Sodium Chloride Symporter Inhibitors	1980
Moduretic-induced metabolic acidosis and hyperkalaemia. Postgraduate medical journal, 1980, Volume: 56, Issue:655 Topics: Acidosis; Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Pyrazines	1980
[Light-induced dermatoses during moduretic therapy]. Lakartidningen, 1980, Aug-06, Volume: 77, Issue:32-33 Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Photosensitivity Disorders; Pyrazines	1980
Amiloride-induced hyponatremia. Acta medica Scandinavica, 1980, Volume: 208, Issue:6 Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines	1980
Contrasting effects of pyrazinoylguanidine and hydrochlorothiazide in patients with renal insufficiency. Journal of clinical pharmacology, 1993, Volume: 33, Issue:6 Topics: Adult; Aged; Blood Glucose; Cholesterol; Electrolytes; Female; Guanidines; Humans; Hydrochlorothiazide; Male; Middle Aged; Pyrazines; Renal Insufficiency; Single-Blind Method; Triglycerides; Urea	1993
Studies on pyrazinoylguanidine. 1. Characterization of metabolic effects in diabetic rats. Pharmacology, 1996, Volume: 52, Issue:3 Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Female; Guanidines; Hydrochlorothiazide; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Rats, Zucker; Streptozocin	1996
Studies on pyrazinoylguanidine. 5. Temporal effects over 24 weeks demonstrating attenuation of diabetic nephropathy in STZ-diabetic rats. Pharmacology, 1997, Volume: 54, Issue:5 Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Guanidines; Hydrochlorothiazide; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Kidney; Kidney Function Tests; Male; Molecular Weight; Pyrazines; Rats; Rats, Sprague-Dawley; Serum Albumin; Streptozocin	1997
Saliva versus plasma pharmacokinetics: theory and application of a salivary excretion classification system. Molecular pharmaceutics, 2012, Aug-06, Volume: 9, Issue:8 Topics: Acetates; Anthraquinones; Azithromycin; Benzhydryl Compounds; Cinacalcet; Cloxacillin; Cresols; Cyclopropanes; Female; Fluorobenzenes; Humans; Hydrochlorothiazide; Losartan; Male; Metformin; Naphthalenes; Phenylpropanolamine; Piroxicam; Pyrazines; Pyrimidines; Quinolines; Rosuvastatin Calcium; Saliva; Sitagliptin Phosphate; Sulfides; Sulfonamides; Tamsulosin; Tolterodine Tartrate; Triazoles	2012