hydrochlorothiazide and prazosin

hydrochlorothiazide has been researched along with prazosin in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	48 (60.76)	18.7374
1990's	10 (12.66)	18.2507
2000's	14 (17.72)	29.6817
2010's	6 (7.59)	24.3611
2020's	1 (1.27)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Caron, G; Ermondi, G; Lorenti, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Schirger, A; Sheps, SG	1
Kontro, J; Kyöstilä, S; Mattila, MJ; Pitkäjärvi, T	1
Itskovitz, HD; Kochar, MS; Zeller, JR	1
Idahosa, PE; Oviasu, VO	1
Idahosa, PE; Oviasu, OV	1
Agabiti-Rosei, E; Beschi, M; Calebich, S; Castellano, M; Muiesan, G; Muiesan, ML; Rizzoni, D; Zulli, R	1
Filatova, NP; Metelitsa, VI	3
Overlack, A; Stumpe, KO	1
Solomon, R	1
Balás-Eltes, A; Farsang, C; Fehér, J; Péter, M	1
Nelson, EB; Pool, JL; Taylor, AA	1
Berkson, DM; Dyer, AR; Gosch, FC; Hershinow, P; Stamler, J; Stamler, R	2
Cervenka, JH; Dinh, T; O'Connor, DT; Takiyyuddin, MA; Witztum, JL	1
Batey, DM; Jeffrey, SS; Lasser, NL; Lasser, VI; Nicolich, MJ	1
Duman, EL; Komsuoğlu, B; Komsuoğlu, SS; Ozgür, O	1
Goldberg, MR; Rockhold, FW; Thompson, WL	1
Berkson, DM; Dyer, A; Gosch, FC; Hershinow, P; Stamler, J; Stamler, R	1
Ruoff, G	1
Pool, JL	1
Claessens, J; Nelemans, F; Riesen, W; Streulens, Y; Trost, BN; Weidmann, P	1
Mayleben, DW; Scharf, MB	1
Itskovitz, HD; Khoury, S; Krug, K; Mollura, JL	1
Batey, DM; Hamill, SJ; Lasser, NL; Lasser, VI; Nash, J	1
Cox, DA; Leader, JP; Milson, JA; Singleton, W	1
Hamilton, BP	1
Daae, L; Hjermann, I; Hjortdahl, P; Holme, I; von Krogh, H	1
Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E	1
Anshelevich, IuV; Dumesh, SZ; Itskovich, VS; Orlova, VP; Raĭbaert, IaIa	1
Alderman, MH; Carroll, L; Davis, TK	1
Freis, ED; Kyle, MC	1
Hengeveld, WL; Schouten, JA; Westerman, RF	1
Metel'skaia, VA; Mustafaev, II; Oganov, RG; Perova, NV; Postol'nikov, SF	1
Bengtsson, C	1
Chernow, B; Coleman, MD; Lake, CR; Zaloga, GP; Ziegler, MG	1
Benowitz, N; Inouye, I; Loge, D; Massie, B; Simpson, P; Topic, N	1
Carver, LA; Lee, CH; Strosberg, AM	1
Moyer, JH	1
Freslon, JL; Giudicelli, JF; Richer, C	1
Lipson, LG	1
Blumenthal, SS; Kalbfleisch, JH; Kochar, MS; Maierhofer, WJ	1
Eide, I; Foss, OP; Helgeland, A; Kjeldsen, S; Leren, P	1
Jounela, AJ; Karppanen, H; Salmela, PI	1
Kaplan, HR; Smith, RD; Tessman, DK	1
Russell, R; Sova-Schultz, K; Walker, WG; Whelton, PK; Wyndham, R	1
Maxwell, M; Okun, R	1
Alderman, MH	1
Cushman, WC; Freis, ED; Fye, C; Gottdiener, J; Hamburger, RJ; Kochar, MS; Lakshman, R; Massie, BM; Materson, BJ; Reda, DJ	1
Adigun, AQ; Afolabi, MA; Ajayi, AA; Ajayi, OE; Akintomide, AO; Balogun, MO	1
Inada, Y; Kanagawa, R; Nishikawa, K; Ojima, M; Sanada, T; Wada, T	1
Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW	1
Hall, DR; Odendaal, HJ	1
Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ	1
Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW	1
Leenen, FH; Ruzicka, M	1
Davies, AE; Okoro, EO	1
Braun, U; Poon, IO	1
Cho, MC; Ku, JH; Paick, JS	1
Beil, M; Danhof, M; Fu, F; Luttringer, O; Ploeger, BA; Rigel, DF; Snelder, N; Stanski, DR	1
Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM	1

Reviews

4 review(s) available for hydrochlorothiazide and prazosin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Review of the effects of doxazosin, a new selective alpha 1-adrenergic inhibitor, on lipoproteins in patients with essential hypertension. The American journal of medicine, 1989, Aug-16, Volume: 87, Issue:2A Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Doxazosin; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins; Prazosin	1989
Drug systems approach to hypertension. Pennsylvania medicine, 1984, Volume: 87, Issue:5 Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa; Patient Compliance; Prazosin; Proteinuria; Renin-Angiotensin System; Reserpine; Spironolactone	1984
Combination therapy as first-line treatment of arterial hypertension. The Canadian journal of cardiology, 2002, Volume: 18, Issue:12 Topics: Antihypertensive Agents; Atenolol; Captopril; Diltiazem; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Prazosin; Treatment Outcome	2002

Trials

36 trial(s) available for hydrochlorothiazide and prazosin

Article	Year
Prazosin-new hypertensive agent. A double-blind crossover study in the treatment of hypertension. JAMA, 1977, Mar-07, Volume: 237, Issue:10 Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Quinazolines	1977
Antihypertensive drug combinations: prazosin, hydrochlorothiazide and clonidine. Annals of clinical research, 1977, Volume: 9, Issue:5 Topics: Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Prazosin; Quinazolines; Time Factors	1977
Prazosin in hypertension with and without methyldopa. Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:2 Topics: Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Prazosin; Quinazolines	1979
[The results of the comparative study of nadolol, propranolol, prazosin and hydrochlorothiazide in patients with arterial hypertension in a 12-month stepped-plan treatment (cooperative research). The Working Group of the Cooperative Program to Study New P Terapevticheskii arkhiv, 1991, Volume: 63, Issue:8 Topics: Adult; Blood Pressure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Prazosin; Propranolol; Remission Induction; Time Factors; USSR	1991
The results of the comparative study of nadolol, propranolol, prazosin and hydrochlorothiazide in patients with arterial hypertension in a 12-month stepped-plan treatment (cooperative research). The Working Group of the Cooperative Program to Study New Pr Terapevticheskii arkhiv, 1991, Volume: 63, Issue:8 Topics: Adult; Blood Pressure; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Patient Dropouts; Prazosin; Propranolol; Remission Induction; Time Factors; USSR	1991
[Role of a beta adrenergic blocking agent nadolol (corgard) in prevention of arterial hypertension: a 6-month treatment (cooperative study)]. Kardiologiia, 1990, Volume: 30, Issue:5 Topics: Adult; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Nadolol; Prazosin; Propranolol; Time Factors	1990
Comparison of the effect of indoramin and prazosin on blood pressure and lipid profiles in essential hypertension. Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 2 Topics: Adult; Aged; Blood Pressure; Cholesterol; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Indoles; Indoramin; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Middle Aged; Prazosin	1986
Antihypertensive effects of indoramin and prazosin in combination with hydrochlorothiazide. Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 2 Topics: Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Indoles; Indoramin; Prazosin	1986
Prazosin improves atherogenic index and inhibits the deleterious effect of dihydrochlorothiazide in patients with essential hypertension. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 12 Topics: Adult; Aged; Blood Pressure; Cholesterol; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prazosin; Triglycerides; Uric Acid	1987
Initial antihypertensive drug therapy--a comparison of alpha-blocker (prazosin) and diuretic (hydrochlorothiazide). Brief summary of a randomized, controlled trial. The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B Topics: Blood Pressure; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prazosin; Random Allocation	1989
Selective alpha-blockade versus angiotensin-converting enzyme inhibition as initial antihypertensive therapy. Effects on circulating lipoproteins. The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B Topics: Adult; Aged; Apolipoproteins; Captopril; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Prazosin; Random Allocation	1989
Prazosin versus hydrochlorothiazide as initial antihypertensive therapy in black versus white patients. The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B Topics: Adult; Aged; Black People; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Prazosin; Random Allocation; White People	1989
The effect of chronic antihypertensive therapy on the index of left ventricular mass in patients with essential hypertension. International journal of cardiology, 1989, Volume: 22, Issue:1 Topics: Adult; Antihypertensive Agents; Atenolol; Cardiac Volume; Clinical Trials as Topic; Echocardiography; Female; Follow-Up Studies; Heart Ventricles; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Male; Middle Aged; Prazosin; Random Allocation; Reserpine	1989
Beneficial effects of pinacidil on blood lipids: comparisons with prazosin and placebo in patients with hypertension. Pinacidil-Prazosin and Pinacidil-Placebo Research Groups, Lilly Research Laboratories. The Journal of laboratory and clinical medicine, 1989, Volume: 114, Issue:6 Topics: Antihypertensive Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Guanidines; Humans; Hydrochlorothiazide; Pinacidil; Prazosin; Propranolol; Random Allocation; Risk Factors; Triglycerides	1989
Initial antihypertensive drug therapy: alpha blocker or diuretic. Interim report of a randomized, controlled trial. The American journal of medicine, 1986, Feb-14, Volume: 80, Issue:2A Topics: Adrenergic alpha-Antagonists; Adult; Cholesterol; Clinical Trials as Topic; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Lipid Metabolism; Male; Middle Aged; Prazosin; Random Allocation; Triglycerides	1986
Comparative trials of terazosin with other antihypertensive agents. The American journal of medicine, 1986, May-23, Volume: 80, Issue:5B Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Piperazines; Prazosin; Random Allocation	1986
Plasma lipid lowering effects of doxazosin, a new selective alpha1 adrenergic inhibitor for systemic hypertension. The American journal of cardiology, 1987, May-29, Volume: 59, Issue:14 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Doxazosin; Humans; Hydrochlorothiazide; Hypertension; Lipids; Placebos; Prazosin	1987
Comparative effects of doxazosin and hydrochlorothiazide on serum lipids and blood pressure in essential hypertension. The American journal of cardiology, 1987, May-29, Volume: 59, Issue:14 Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prazosin; Prospective Studies; Random Allocation	1987
Comparative effects of prazosin and hydrochlorothiazide on sexual function in hypertensive men. The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B Topics: Blood Pressure; Humans; Hydrochlorothiazide; Hypertension; Male; Penile Erection; Prazosin; Sleep, REM	1989
The long-term antihypertensive effects of prazosin and atenolol. The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B Topics: Atenolol; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prazosin; Time Factors	1989
Effects of antihypertensive therapy on blood pressure control, cognition, and reactivity. A placebo-controlled comparison of prazosin, propranolol, and hydrochlorothiazide. The American journal of medicine, 1989, Jan-23, Volume: 86, Issue:1B Topics: Antihypertensive Agents; Blood Pressure; Cognition; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prazosin; Propranolol; Reaction Time; Stress, Psychological	1989
The antihypertensive effects of doxazosin: a clinical overview. British journal of clinical pharmacology, 1986, Volume: 21 Suppl 1 Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Male; Metoprolol; Middle Aged; Nadolol; Prazosin; Propanolamines; Random Allocation; Risk; Triglycerides	1986
Treatment of essential hypertension with PN 200-110 (isradipine). The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3 Topics: Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Oxadiazoles; Prazosin; Propranolol; Random Allocation; Time Factors	1987
A 24-week multicenter double-blind study of doxazosin and hydrochlorothiazide in patients with mild to moderate essential hypertension. Acta medica Scandinavica, 1987, Volume: 221, Issue:5 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prazosin; Random Allocation; Time Factors	1987
Initial antihypertensive drug therapy. Final report of a randomized, controlled trial comparing alpha-blocker and diuretic. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 12, Issue:6 Topics: Adult; Aged; Blood Pressure; Cholesterol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Random Allocation; Triglycerides	1988
Initial antihypertensive therapy. Comparison of prazosin and hydrochlorothiazide. The American journal of medicine, 1986, Feb-14, Volume: 80, Issue:2A Topics: Adult; Aged; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Prospective Studies; Random Allocation	1986
Prazosin once or twice daily? European journal of clinical pharmacology, 1985, Volume: 28, Issue:1 Topics: Adult; Aged; Amiloride; Atenolol; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Prazosin; Propranolol; Quinazolines	1985
[Change in the spectrum of lipids and apoproteins A1 and B as affected by hypothiazide and pratsiol in patients with hypertension]. Kardiologiia, 1985, Volume: 25, Issue:8 Topics: Adult; Apolipoproteins A; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Humans; Hydrochlorothiazide; Hypertension; Lipids; Middle Aged; Prazosin; Triglycerides	1985
Double-blind comparison of dihydralazine and prazosin in hypertensive patients on the diuretic-reserpine regimen. Annals of clinical research, 1981, Volume: 13, Issue:6 Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Prazosin; Quinazolines; Renin; Reserpine; Triamterene	1981
Comparison of prazosin with hydralazine in patients receiving hydrochlorothiazide. A randomized, double-blind clinical trial. Circulation, 1981, Volume: 64, Issue:4 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pulse; Quinazolines; Random Allocation	1981
[Comparative study between prazosin and methyldopa in essential arterial hypertension: results of a parallel, randomized double-blind trial]. Cardiology, 1980, Volume: 66 Suppl 2 Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Prazosin; Quinazolines; Random Allocation; Renin	1980
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. The New England journal of medicine, 1993, Apr-01, Volume: 328, Issue:13 Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Clonidine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin	1993
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. Circulation, 1997, Apr-15, Volume: 95, Issue:8 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Clonidine; Cohort Studies; Diltiazem; Diuretics; Double-Blind Method; Echocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Organ Size; Prazosin; Prevalence; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States; United States Department of Veterans Affairs	1997
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1998, Volume: 60, Issue:1 Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Gestational Age; Humans; Hydrochlorothiazide; Hypertension; Length of Stay; Methyldopa; Nifedipine; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Treatment Outcome	1998
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. Archives of internal medicine, 1999, Mar-22, Volume: 159, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Clonidine; Diltiazem; Diuretics; Double-Blind Method; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Potassium; Prazosin; Time Factors; Treatment Outcome; United States	1999
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:4 Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Diltiazem; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pressure; Pulse; Randomized Controlled Trials as Topic; Systole; Time Factors; Treatment Outcome	2001

Other Studies

39 other study(ies) available for hydrochlorothiazide and prazosin

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction. Journal of medicinal chemistry, 2004, Jul-29, Volume: 47, Issue:16 Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Open clinical evaluation of prazosin in hypertensive Nigerians. Nigerian medical journal : journal of the Nigeria Medical Association, 1979, Volume: 9, Issue:2 Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Quinazolines	1979
Variability in effect of low doses of prozosin in hypertensive Nigerians. Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:6 Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Prazosin; Quinazolines	1976
Reduction of left ventricular hypertrophy after longterm antihypertensive treatment with doxazosin. Journal of human hypertension, 1992, Volume: 6, Issue:1 Topics: Adrenergic alpha-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Diastole; Dose-Response Relationship, Drug; Doxazosin; Drug Therapy, Combination; Female; Heart Rate; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Organ Size; Prazosin; Renin; Rest; Stress, Physiological; Systole; Time Factors	1992
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models. Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Diuretics; Electrolytes; Hydrochlorothiazide; Hypertension; Hypertrophy; Indapamide; Kidney; Male; Prazosin; Pyridines; Rats; Rats, Inbred SHR	1988
[Combined antihypertensive pharmacotherapy]. Klinicheskaia meditsina, 1988, Volume: 66, Issue:8 Topics: Adult; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Reserpine; Time Factors	1988
[Efficacy of a graded plan for long-term prevention using antihypertensive drugs. Work Group for the Cooperative Study for the Testing of New Preparations for the Prevention of Arterial Hypertension (CSPPAH)]. Kardiologiia, 1987, Volume: 27, Issue:1 Topics: Adult; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Systole	1987
Serial measurements of systolic time intervals during treatment with hydrochlorothiazide alone and combined with other antihypertensive agents. The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1 Topics: Antihypertensive Agents; Drug Therapy, Combination; Electrocardiography; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Myocardial Contraction; Oxprenolol; Prazosin; Propranolol; Systole; Time Factors	1985
[Hypotensive effect and tolerability of a short course of treatment with prazosin (pratsiol) and hydralazine (apressin) in a cooperative study of new drugs for the prevention of arterial hypertension]. Kardiologiia, 1985, Volume: 25, Issue:1 Topics: Adult; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Quinazolines; Time Factors	1985
Impairment of physical performance after treatment with beta blockers and alpha blockers. British medical journal (Clinical research ed.), 1984, Mar-03, Volume: 288, Issue:6418 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alprenolol; Heart Rate; Humans; Hydrochlorothiazide; Labetalol; Male; Metoprolol; Physical Exertion; Pindolol; Prazosin; Propranolol; Running	1984
Effect of antihypertensive therapy on sympathetic nervous system activity in patients with essential hypertension. Federation proceedings, 1984, Volume: 43, Issue:1 Topics: Antihypertensive Agents; Captopril; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reserpine; Sympathetic Nervous System; Vasodilator Agents	1984
Monotherapy in mild to moderate hypertension: comparison of hydrochlorothiazide, propranolol and prazosin. The American journal of cardiology, 1984, Jan-27, Volume: 53, Issue:3 Topics: Adult; Aged; Blood Pressure; Erythrocytes; Female; Heart; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Physical Exertion; Posture; Prazosin; Propranolol; Quinazolines; Radionuclide Imaging; Random Allocation; Sodium Pertechnetate Tc 99m; Stroke Volume; Technetium	1984
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats. Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 261, Issue:1 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains	1983
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat]. Paroi arterielle, 1980, Volume: 6, Issue:4 Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Relationship, Drug; Hydrochlorothiazide; Hypertension; Male; Nicardipine; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents	1980
Treatment of hypertension in diabetic men: problems with sexual dysfunction. The American journal of cardiology, 1984, Jan-27, Volume: 53, Issue:3 Topics: Antihypertensive Agents; Blood Pressure; Diabetic Angiopathies; Erectile Dysfunction; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Prazosin	1984
Prazosin versus propranolol plus prazosin: a comparison in diuretic-treated hypertensive patients. The American journal of cardiology, 1984, Jan-27, Volume: 53, Issue:3 Topics: Aged; Blood Pressure; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Quinazolines; Random Allocation; Time Factors	1984
Changes in the lipoprotein profile during antihypertensive therapy. Acta pharmacologica et toxicologica, 1984, Volume: 54 Suppl 1 Topics: Antihypertensive Agents; Cholesterol; Humans; Hydrochlorothiazide; Lipoproteins; Methyldopa; Prazosin; Propranolol; Triglycerides; Uric Acid	1984
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2 Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Hydrochlorothiazide; Hypertension; Indomethacin; Male; Methyltyrosines; Prazosin; Propranolol; Quinazolines; Rats; Renin	1981
[Long-term antihypertensive treatment with prazosin in combination with a diuretic]. Cardiology, 1980, Volume: 66 Suppl 2 Topics: Adult; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypotension, Orthostatic; Male; Middle Aged; Polythiazide; Prazosin; Quinazolines; Time Factors; Triamterene	1980
[Control of arterial hypertension at the work site of the patient: retrospective review of prazosin and propanolol]. Cardiology, 1980, Volume: 66 Suppl 2 Topics: Adult; Aged; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Occupational Health Services; Prazosin; Propranolol; Quinazolines; Retrospective Studies	1980
Oral therapy with combined enalapril, prazosin and hydrochlorothiazide in the acute treatment of severe hypertension in Nigerians. European journal of clinical pharmacology, 1996, Volume: 51, Issue:1 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nigeria; Prazosin; Sodium Chloride Symporter Inhibitors	1996
Combined effects of the angiotensin II antagonist candesartan cilexetil (TCV-116) and other classes of antihypertensive drugs in spontaneously hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:4 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Hydrochlorothiazide; Male; Nitrobenzenes; Piperazines; Prazosin; Rats; Rats, Inbred SHR; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles	1996
Sponsorship of educational programmes in Nigerian medical and pharmacy schools by pharmaceutical companies: possible risk implication for public health. Ethics & medicine : a Christian perspective on issues in bioethics, 2001,Spring, Volume: 17, Issue:1 Topics: Advertising; Conflict of Interest; Drug Industry; Education, Medical; Education, Pharmacy; Financial Support; Humans; Hydrochlorothiazide; Hypertension; Nigeria; Prazosin	2001
High prevalence of orthostatic hypotension and its correlation with potentially causative medications among elderly veterans. Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:2 Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents; Drug Therapy; Female; Furosemide; Health Services for the Aged; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypotension, Orthostatic; Lisinopril; Male; Outpatients; Patient Selection; Prazosin; Prevalence; Retrospective Studies; Veterans	2005
Alpha-blocker plus diuretic combination therapy as second-line treatment for nocturia in men with LUTS: a pilot study. Urology, 2009, Volume: 73, Issue:3 Topics: Adrenergic alpha-Antagonists; Aged; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Male; Nocturia; Pilot Projects; Prazosin; Prospective Studies; Prostatism	2009
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling. British journal of pharmacology, 2014, Volume: 171, Issue:22 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Models, Biological; Prazosin; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY	2014
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Jun-01, Volume: 1146 Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan	2020