hydrochlorothiazide and oxprenolol

hydrochlorothiazide has been researched along with oxprenolol in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199021 (63.64)18.7374
1990's0 (0.00)18.2507
2000's7 (21.21)29.6817
2010's5 (15.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Akamatsu, M1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Materson, BJ; Michael, UF; Oster, JR; Perez-Stable, EC1
Colombi, A; Motolese, M; Muiesan, G2
Dannhorn, R; Müller, AA1
Mauracher, EH; Rivier, JL1
Bulpitt, CJ; Fletcher, AE; Hill, JF1
Backhouse, CI; Rowley-Jones, D; Spencer-Mills, L1
Garrido Peralta, M; Gras, X; Ocón, J; Oliván, J; Rodicio, JL; Rodríguez Alvarez, J; Ruilope, L; Seco Vasco, J1
Mutschler, E; Prinoth, M; Spahn, H1
Freis, ED; Kyle, MC1
Jänne, J; Keyriläinen, O; Koskinen, P; Leskinen, O; Pitkäjärvi, T; Reinikainen, M; Siitonen, L1
de Wurstemberger, B; Gysling, E1
Alhenc-Gelas, F; Amiot, AM; Chatellier, G; Corvol, P; Ménard, J; Sassano, P1
Freis, ED1
Fernandez, PG; Idikio, H; Kim, BK; Triggle, CR1
Friedman, BA; Glazer, N; Gray, JM; Gross, S; Hla, KM; Materson, BJ; Neidorf, BS1
Friedman, B; Gray, JM; Gross, S; Levit, SA1
Ellis, RA1
Ambrosioni, E; Borghi, C; Costa, FV1
Pedrinelli, R; Salvetti, A; Simonini, N1
García Sacristán, A1

Trials

13 trial(s) available for hydrochlorothiazide and oxprenolol

ArticleYear
Antihypertensive effects of oxprenolol and propranolol.
    Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Propranolol; Time Factors

1976
Hypotensive effect of oxprenolol in mild to moderate hypertension: a multicentre controlled study.
    European journal of clinical pharmacology, 1975, Volume: 8, Issue:1

    Topics: Clinical Trials as Topic; Dihydralazine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Oxprenolol; Regression Analysis

1975
Angiotensin converting enzyme inhibitors and quality of life: the European trial.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1985, Volume: 3, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Prospective Studies; Quality of Life; Random Allocation

1985
Hydrochlorothiazide and triamterene with sustained-release oxprenolol in the treatment of hypertension.
    Current medical research and opinion, 1986, Volume: 10, Issue:3

    Topics: Aged; Creatinine; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kidney Function Tests; Male; Middle Aged; Oxprenolol; Potassium; Random Allocation; Triamterene; Urea; Uric Acid

1986
[Multicenter study of the efficacy of 3 antihypertensive regimens: captopril + hydrochlorothiazide, oxprenolol + hydrochlorothiazide, and alphamethyldopa + hydrochlorothiazide].
    Medicina clinica, 1985, Nov-09, Volume: 85, Issue:15

    Topics: Adult; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Prospective Studies; Spain

1985
Hydralazine and beta-adrenergic blockade in the treatment of hypertension.
    Annals of clinical research, 1974, Volume: 6, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Placebos

1974
Hypotensive effect of oxprenolol in mild hypertension: a co-operative controlled study.
    Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1

    Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Drug Interactions; Drug Synergism; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Placebos; Time Factors

1973
A double-blind randomized evaluation of converting enzyme inhibition as the first-step treatment of mild to moderate hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:2

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Potassium; Random Allocation

1984
Veterans Administration cooperative study on nadolol as monotherapy and in combination with a diuretic.
    American heart journal, 1984, Volume: 108, Issue:4 Pt 2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Bendroflumethiazide; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Oxprenolol; Propanolamines; Propranolol; Random Allocation; Renin; United States; United States Department of Veterans Affairs

1984
Slow-release oxprenolol compared with oxprenolol in hypertensive patients: a multicenter clinical trial.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:1

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol

1983
United States experience with oxprenolol in hypertension.
    The American journal of cardiology, 1983, Nov-10, Volume: 52, Issue:9

    Topics: Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Oxprenolol; Placebos; Propranolol; Time Factors; United States

1983
Clinical responses to oxprenolol in the elderly.
    The American journal of cardiology, 1983, Nov-10, Volume: 52, Issue:9

    Topics: Aged; Aging; Clinical Trials as Topic; Drug Therapy, Combination; Drug Tolerance; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Oxprenolol; Placebos

1983
Captopril and oxprenolol in a fixed combination with thiazide diuretics: comparison of their antihypertensive efficacy and metabolic effects.
    Clinical therapeutics, 1984, Volume: 6, Issue:5

    Topics: Adult; Blood Pressure; Captopril; Chlorthalidone; Cholesterol; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Proline; Random Allocation

1984

Other Studies

20 other study(ies) available for hydrochlorothiazide and oxprenolol

ArticleYear
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
[Ambulatory treatment of arterial hypertension urinary the new combination "saluretic and beta-sympatholytic"].
    Fortschritte der Medizin, 1975, Oct-23, Volume: 93, Issue:30

    Topics: Chemical Phenomena; Chemistry; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol

1975
[Treatment of essential hypertension with Transicor 80 and Esidrex K under medical practice conditions].
    Schweizerische medizinische Wochenschrift, 1976, Mar-06, Volume: 106, Issue:10

    Topics: Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Oxprenolol

1976
The development of reliable compliance tests for antihypertensive drugs.
    European journal of clinical pharmacology, 1986, Volume: 29, Issue:5

    Topics: Antihypertensive Agents; Colorimetry; Eating; Female; Habits; Humans; Hydrochlorothiazide; Male; Oxprenolol; Patient Compliance; Pindolol; Spectrometry, Fluorescence; Time Factors

1986
Serial measurements of systolic time intervals during treatment with hydrochlorothiazide alone and combined with other antihypertensive agents.
    The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1

    Topics: Antihypertensive Agents; Drug Therapy, Combination; Electrocardiography; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Myocardial Contraction; Oxprenolol; Prazosin; Propranolol; Systole; Time Factors

1985
[Effects of combined treatment with hydrochlorothiazide and oxprenolol on arterial pressure and activity of plasma renin. Preliminary results].
    Schweizerische medizinische Wochenschrift, 1974, Dec-07, Volume: 104, Issue:49

    Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Posture; Renin

1974
Regression of left ventricular hypertrophy and control of hypertension in the spontaneously hypertensive rat (SHR): oxprenolol versus hydrochlorothiazide.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1983, Volume: 6, Issue:1

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Heart Ventricles; Hydrochlorothiazide; Hypertension; Male; Organ Size; Oxprenolol; Rats; Rats, Inbred Strains

1983
The renin-angiotensin-aldosterone system and blood pressure during oxprenolol treatment in hypertensive patients pretreated with diuretics.
    International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:11

    Topics: Adult; Aldosterone; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Renin; Renin-Angiotensin System

1982
[Combined action of oxprenolol, hydrochlorothiazide and hydralazine in rats with metacorticoid induced hypertension].
    Revista clinica espanola, 1980, Jun-30, Volume: 157, Issue:6

    Topics: Animals; Desoxycorticosterone; Drug Evaluation; Drug Therapy, Combination; Hydralazine; Hydrochlorothiazide; Hypertension; Oxprenolol; Rats

1980