hydrochlorothiazide and olmesartan

hydrochlorothiazide has been researched along with olmesartan in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (17.19)	29.6817
2010's	49 (76.56)	24.3611
2020's	4 (6.25)	2.80

Authors

Authors	Studies
Andricopulo, AD; Moda, TL; Montanari, CA	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Laeis, P; Rump, LC; Sellin, L; Stegbauer, J	1
Böhm, M; Ewald, S	1
Dubiel, R; Izzo, JL; Neutel, JM; Silfani, T; Walker, F	1
Corradi, L; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A	1
Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A	1
Ruilope, LM	1
Dominiczak, AF; Fields, L; Graham, D; Hamilton, CA; Koh-Tan, HH; McBride, MW; Nicoll, G; Young, B	1
Eguchi, K; Ishikawa, J; Kario, K; Matsui, Y; Miyashita, H; O'Rourke, MF; Shimada, K	1
Blacher, J; Protogerou, A; Safar, ME	1
Araki, S; Hirooka, Y; Kishi, T; Sunagawa, K; Utsumi, H; Yasukawa, K	1
Kereiakes, DJ; Neutel, JM; Shojaee, A; Stoakes, KA; Waverczak, WF; Xu, J	1
Burnier, M; Coltamai, L; Maillard, M; Simon, A; Vogt, B	1
Feng, S; Hu, P; Jiang, J; Liu, D; Wang, P	1
Comi-Diaz, C; Martinez-Martin, FJ; Pedrianes-Martin, P; Peiro-Martinez, I; Rodriguez-Rosas, H; Soriano-Perera, P	1
Eguchi, K; Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K	1
Kashihara, N; Nagasu, H; Sasaki, T; Satoh, M; Tomita, N; Yorimitsu, D	1
Makris, T; Stefanadis, C; Thomopoulos, C; Tsioufis, C	1
McInnes, GT	1
Palatini, P	1
Graff, A; Hsueh, WA; Jones, CJ; Littlejohn, TJ; Nesbitt, SD; Neutel, JM; Qian, C; Shojaee, A; Waverczak, WF; Weir, MR	1
Narkiewicz, K	1
Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn Iii, T; Melino, M; Oparil, S	1
Ahbap, E; Basturk, T; Borlu, F; Damar, AB; Koc, Y; Mazi, E; Sakaci, T; Unsal, A	1
Hara, T; Hayden, MR; Hitomi, H; Ichimura, A; Ito, S; Kaifu, K; Kawachi, H; Kiyomoto, H; Kobori, H; Kohno, M; Matsumoto, S; Nishijima, Y; Nishiyama, A; Ohsaki, H; Sofue, T; Sowers, JR; Urushihara, M; Whaley-Connell, A	1
Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A	1
Chrysant, SG; Fernandez, V; Heyrman, R; Izzo, JL; Kereiakes, DJ; Lee, J; Littlejohn, T; Melino, M; Oparil, S	2
Hoshide, S; Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K	1
Bilo, G; Parati, G	1
Ishikawa, J; Kario, K; Matsui, Y; O'Rourke, MF; Shimada, K	1
Bakris, GL; Cushman, WC; Kupfer, S; Lloyd, E; Roberts, A; Sica, D; Weber, MA; White, WB	2
Maa, JF; Neutel, J; Shojaee, A	1
Ammentorp, B; Christian Rump, L; Laeis, P; Volpe, M	1
Gumustas, M; Kurbanoglu, S; Ozkan, SA	1
Paneni, F; Passerini, J; Tocci, G; Volpe, M	1
de la Sierra, A; Volpe, M	1
Bramlage, P; Fronk, EM; Ketelhut, R; Schmieder, RE; Wolf, WP; Zemmrich, C	1
Chrysant, SG	1
Amaya, N; Arakawa, K; Fukuoka, Y; Ishida, K; Lee, JD; Morishita, T; Nakano, A; Tada, H; Uzui, H	1
de la Sierra, A; Kreutz, R; Laurent, S; Manolis, AJ; Volpe, M	1
Bramlage, P; Fronk, EM; Ketelhut, R; Schmieder, RE; Smolnik, R; Wolf, WP; Zemmrich, C	1
Ammentorp, B; de la Sierra, A; Laeis, P; Volpe, M	1
O'Brien, E	1
Ammentorp, B; de la Sierra, A; Kreutz, R; Laeis, P	1
Angeloni, E; Lombardo, P; Pirelli, M; Refice, S; Vitaterna, A	1
Bramlage, P; Fronk, EM; Schmieder, RE; Smolnik, R; Sutton, G; Wolf, WP	1
Schlimpert, V	1
Ahn, Y; Bae, JH; Jung, HW; Kang, DH; Kim, CH; Kim, KI; Park, CG	1
Brazier, JE; Guest, JF; Haag, U; Marques da Silva, P; Soro, M	1
Abdelhameed, AS; Bakheit, AH; Darwish, HW	1
Douros, A; Kreutz, R; Scholze, J	1
van der Merwe, WM	1
Bakris, GL; Cushman, WC; Ferdinand, KC; Lloyd, E; Weber, MA; White, WB; Wu, J	1
Ahn, KT; Cho, BR; Kim, BJ; Kim, DK; Lee, SY; Lee, WS; Park, JI; Sung, J	1
Burnier, M; Redon, J; Volpe, M	1
Hong, JH; Hyun, D; Kim, GH; Kim, HL; Kim, W; Lim, S; Min, KW; Oh, J; Park, SD; Shin, J	1

Reviews

5 review(s) available for hydrochlorothiazide and olmesartan

Article	Year
Clinical efficacy and safety of olmesartan/hydrochlorothiazide combination therapy in patients with essential hypertension. Vascular health and risk management, 2008, Volume: 4, Issue:6 Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Practice Guidelines as Topic; Severity of Illness Index; Tetrazoles; Time Factors; Treatment Outcome	2008
Angiotensin II receptor blocker combinations: from guidelines to clinical practice. Blood pressure, 2012, Volume: 21, Issue:2 Topics: Amlodipine; Angiotensin Receptor Antagonists; Antineoplastic Agents; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Practice Guidelines as Topic; Tetrazoles	2012
Triple combination therapy to improve blood pressure control: experience with olmesartan-amlodipine-hydrochlorothiazide therapy. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:18 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles	2012
Effectiveness of the fixed-dose combination of olmesartan/amlodipine/hydrochlorothiazide for the treatment of hypertension in patients stratified by age, race and diabetes, CKD and chronic CVD. Expert review of cardiovascular therapy, 2013, Volume: 11, Issue:9 Topics: Age Factors; Amlodipine; Cardiovascular Diseases; Diabetes Complications; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Renal Insufficiency, Chronic; Tetrazoles	2013
Single-Pill Combination with Three Antihypertensive Agents to Improve Blood Pressure Control in Hypertension: Focus on Olmesartan-Based Combinations. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2023, Volume: 30, Issue:2 Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Olmesartan Medoxomil	2023

Trials

28 trial(s) available for hydrochlorothiazide and olmesartan

Article	Year
Adding hydrochlorothiazide to olmesartan dose dependently improves 24-h blood pressure and response rates in mild-to-moderate hypertension. Journal of hypertension, 2005, Volume: 23, Issue:11 Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Tetrazoles; Treatment Outcome	2005
Blood pressure reduction with olmesartan in mild-to-moderate essential hypertension: a planned interim analysis of an open label sub-study in German patients. Current medical research and opinion, 2006, Volume: 22, Issue:7 Topics: Adolescent; Adult; Aged; Angiotensin Receptor Antagonists; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles	2006
Efficacy and safety of treating stage 2 systolic hypertension with olmesartan and olmesartan/HCTZ: results of an open-label titration study. Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:1 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome	2007
Effect of delapril/manidipine vs olmesartan/ hydrochlorothiazide combination on insulin sensitivity and fibrinogen in obese hypertensive patients. Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:5 Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Female; Fibrinogen; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Insulin Resistance; Male; Middle Aged; Nitrobenzenes; Obesity; Piperazines; Tetrazoles	2008
Effects of manidipine/delapril versus olmesartan/hydrochlorothiazide combination therapy in elderly hypertensive patients with type 2 diabetes mellitus. Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:1 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus, Type 2; Dihydropyridines; Diuretics; Drug Combinations; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypotension, Orthostatic; Imidazoles; Indans; Male; Nitrobenzenes; Piperazines; Posture; Prospective Studies; Tetrazoles	2008
Differential effects between a calcium channel blocker and a diuretic when used in combination with angiotensin II receptor blocker on central aortic pressure in hypertensive patients. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aorta; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Time Factors; Treatment Outcome	2009
Effects of an olmesartan medoxomil based treatment algorithm on 24-hour blood pressure control in patients with hypertension and type 2 diabetes. Current medical research and opinion, 2010, Volume: 26, Issue:3 Topics: Aged; Algorithms; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Time Factors	2010
Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans. Journal of hypertension, 2010, Volume: 28, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Imidazoles; Irbesartan; Kidney Tubules; Losartan; Single-Blind Method; Tetrazoles; Valine; Valsartan	2010
Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study. Journal of human hypertension, 2011, Volume: 25, Issue:6 Topics: Adiponectin; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Comorbidity; Cytokines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Insulin Resistance; Intercellular Adhesion Molecule-1; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome; Vascular Cell Adhesion Molecule-1	2011
Association between aldosterone induced by antihypertensive medication and arterial stiffness reduction: the J-CORE study. Atherosclerosis, 2011, Volume: 215, Issue:1 Topics: Aged; Aldosterone; Antihypertensive Agents; Aorta; Azetidinecarboxylic Acid; Blood Flow Velocity; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Imidazoles; Male; Pulsatile Flow; Tetrazoles; Vascular Resistance	2011
A titrate-to-goal study of switching patients uncontrolled on antihypertensive monotherapy to fixed-dose combinations of amlodipine and olmesartan medoxomil ± hydrochlorothiazide. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Self Report; Tetrazoles; Titrimetry; Young Adult	2011
24-hour efficacy and safety of Triple-Combination Therapy With Olmesartan, Amlodipine, and Hydrochlorothiazide: the TRINITY ambulatory blood pressure substudy. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:12 Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors	2011
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:5 Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan	2012
Long-term efficacy and safety of triple-combination therapy with olmesartan medoxomil and amlodipine besylate and hydrochlorothiazide for hypertension. Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:3 Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors	2012
Combined effect of angiotensin II receptor blocker and either a calcium channel blocker or diuretic on day-by-day variability of home blood pressure: the Japan Combined Treatment With Olmesartan and a Calcium-Channel Blocker Versus Olmesartan and Diuretic Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:6 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Tetrazoles; Treatment Outcome	2012
Association of changes in ambulatory arterial stiffness index and pulse wave velocity during antihypertensive treatment: the J-CORE study. American journal of hypertension, 2012, Volume: 25, Issue:8 Topics: Aged; Antihypertensive Agents; Azetidinecarboxylic Acid; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Vascular Stiffness	2012
Azilsartan medoxomil plus chlorthalidone reduces blood pressure more effectively than olmesartan plus hydrochlorothiazide in stage 2 systolic hypertension. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:2 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Black People; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Severity of Illness Index; Tetrazoles; Treatment Outcome; White People	2012
Efficacy of amlodipine/olmesartan ± hydrochlorothiazide in patients uncontrolled on prior calcium channel blocker or angiotensin II receptor blocker monotherapy. Advances in therapy, 2012, Volume: 29, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Comorbidity; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles	2012
Triple-Combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in black and non-black study participants with hypertension: the TRINITY randomized, double-blind, 12-week, parallel-group study. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2012, Aug-01, Volume: 12, Issue:4 Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black People; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles	2012
Efficacy and safety of triple antihypertensive therapy with the olmesartan/amlodipine/hydrochlorothiazide combination. Clinical drug investigation, 2012, Oct-01, Volume: 32, Issue:10 Topics: Adult; Aged; Aging; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Young Adult	2012
Effects of combination therapy with olmesartan and azelnidipine on serum osteoprotegerin in patients with hypertension. Journal of cardiovascular pharmacology and therapeutics, 2014, Volume: 19, Issue:3 Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Azetidinecarboxylic Acid; Biomarkers; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Matrix Metalloproteinase 2; Middle Aged; Osteoprotegerin; Prospective Studies; Tetrazoles	2014
Open-label study assessing the long-term efficacy and safety of triple olmesartan/amlodipine/hydrochlorothiazide combination therapy for hypertension. Advances in therapy, 2014, Volume: 31, Issue:5 Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Time; Treatment Outcome	2014
Efficacy and tolerability of triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide: a subgroup analysis of patients stratified by hypertension severity, age, sex, and obesity. Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:10 Topics: Adult; Age Factors; Aged; Amlodipine; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Obesity; Sex Factors; Tetrazoles	2014
A multicenter, non-comparative study to evaluate the efficacy and safety of fixed-dose olmesartan/amlodipine in Korean patients with hypertension who are naïve or non-responders to anti-hypertensive monotherapy (ACE-HY study). Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:6 Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Male; Middle Aged; Prospective Studies; Republic of Korea; Tetrazoles; Treatment Outcome	2015
Health-related quality of life impact of a triple combination of olmesartan medoxomil, amlodipine besylate and hydrochlorotiazide in subjects with hypertension. Health and quality of life outcomes, 2015, Feb-21, Volume: 13 Topics: Adult; Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Quality of Life; Tetrazoles; Treatment Outcome	2015
A randomized titrate-to-target study comparing fixed-dose combinations of azilsartan medoxomil and chlorthalidone with olmesartan and hydrochlorothiazide in stage-2 systolic hypertension. Journal of hypertension, 2018, Volume: 36, Issue:4 Topics: Aged; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles	2018
Comparison of Effectiveness of Azilsartan Medoxomil and Olmesartan in Blacks Versus Whites With Systemic Hypertension. The American journal of cardiology, 2018, 11-01, Volume: 122, Issue:9 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Black or African American; Chlorthalidone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles; United States; White People	2018
Adherence to triple-component antihypertensive regimens is higher with single-pill than equivalent two-pill regimens: A randomized controlled trial. Clinical and translational science, 2021, Volume: 14, Issue:3 Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome	2021

Other Studies

31 other study(ies) available for hydrochlorothiazide and olmesartan

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of hypertension, 2009, Volume: 27, Issue:8 Topics: Acetylcysteine; Animals; Glutathione Transferase; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Kidney; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Systole; Tetrazoles	2009
Central blood pressure under angiotensin and calcium channel blockade. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4 Topics: Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Imidazoles; Tetrazoles; Treatment Outcome	2009
Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method. Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:12 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Brain; Electron Spin Resonance Spectroscopy; Heart Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Imidazoles; Male; NADPH Oxidases; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Tetrazoles	2009
Simultaneous quantitative determination of olmesartan and hydrochlorothiazide in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Mar-15, Volume: 878, Issue:9-10 Topics: Antihypertensive Agents; Chromatography, Liquid; Humans; Hydrochlorothiazide; Imidazoles; Tandem Mass Spectrometry; Tetrazoles	2010
Comparison of combination therapy of olmesartan plus azelnidipine or hydrochlorothiazide on renal and vascular damage in SHR/NDmcr-cp rats. Kidney & blood pressure research, 2011, Volume: 34, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; Dihydropyridines; Drug Therapy, Combination; Hydrochlorothiazide; Imidazoles; Kidney Diseases; Oxidative Stress; Rats; Rats, Inbred SHR; Tetrazoles; Vascular Diseases	2011
The 'pyrrhic victory' of amlodipine over hydrochlorothiazide in the OLAS Study. Journal of human hypertension, 2011, Volume: 25, Issue:6 Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Body Mass Index; Comorbidity; Drug Therapy, Combination; Endpoint Determination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Life Style; Metabolic Syndrome; Tetrazoles; Treatment Outcome	2011
The effect of antihypertensive agents in people at high risk of cardiovascular disease and diabetes: a view through smoke and mirrors. Journal of human hypertension, 2011, Volume: 25, Issue:6 Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Comorbidity; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Risk Factors; Tetrazoles; Treatment Outcome	2011
Reduction of albuminuria with antihypertensive treatment: is more always better? American journal of hypertension, 2011, Volume: 24, Issue:4 Topics: Albuminuria; Antihypertensive Agents; Azetidinecarboxylic Acid; Dihydropyridines; Humans; Hydrochlorothiazide; Imidazoles; Tetrazoles	2011
Effect of Olmesartan on serum cystatin C levels in the patients with essential hypertension. European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:12 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Cystatin C; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles	2011
Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats. American journal of hypertension, 2012, Volume: 25, Issue:5 Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydralazine; Hydrochlorothiazide; Imidazoles; Juxtaglomerular Apparatus; Male; Membrane Proteins; Podocytes; Rats; Rats, Inbred OLETF; Reserpine; Tetrazoles	2012
Calcium antagonist added to angiotensin receptor blocker: a recipe for reducing blood pressure variability?: evidence from day-by-day home blood pressure monitoring. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:6 Topics: Azetidinecarboxylic Acid; Blood Pressure; Dihydropyridines; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Tetrazoles	2012
[Hypertension: improved therapy adherence after switch to a fixed drug combinations]. MMW Fortschritte der Medizin, 2012, Mar-22, Volume: 154, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Drug Substitution; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Tetrazoles	2012
Simultaneous estimation and validation of some binary mixtures of antihypertensive drugs by RP-LC methods using two new generation silica columns. Journal of pharmaceutical and biomedical analysis, 2013, Volume: 72 Topics: Antihypertensive Agents; Captopril; Chromatography, Reverse-Phase; Hydrochlorothiazide; Imidazoles; Indicators and Reagents; Silicon Dioxide; Solvents; Tetrazoles	2013
Olmesartan-based therapies: an effective way to improve blood pressure control and cardiovascular protection. Journal of hypertension, 2013, Volume: 31 Suppl 1 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Tetrazoles; Treatment Failure	2013
[Hypertension. Goal: achieving target blood pressure with only 1 pill daily]. MMW Fortschritte der Medizin, 2013, Apr-04, Volume: 155, Issue:6 Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Randomized Controlled Trials as Topic; Tetrazoles	2013
Safety, tolerability, and efficacy of a fixed-dose combination of olmesartan 40 mg and hydrochlorothiazide 12.5/25 mg in daily practice. Vascular health and risk management, 2013, Volume: 9 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Austria; Blood Pressure; Diuretics; Drug Combinations; Energy Metabolism; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Motor Activity; Tetrazoles; Time Factors; Treatment Outcome	2013
ARB-based single-pill platform to guide a practical therapeutic approach to hypertensive patients. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2014, Volume: 21, Issue:2 Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Risk Factors; Tablets; Tetrazoles; Treatment Outcome	2014
Clinical impact of patient adherence to a fixed-dose combination of olmesartan, amlodipine and hydrochlorothiazide. Clinical drug investigation, 2014, Volume: 34, Issue:6 Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Essential Hypertension; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Tetrazoles; Young Adult	2014
[Hypertension. Guidelines recommend fixed combinations]. MMW Fortschritte der Medizin, 2014, Apr-17, Volume: 156, Issue:7 Topics: Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Combinations; Guideline Adherence; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Randomized Controlled Trials as Topic; Tetrazoles	2014
If I had resistant hypertension. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Pyrroles; Spironolactone; Tetrazoles; Treatment Failure; Treatment Outcome	2014
Single-pill combination therapy in the initial treatment of marked hypertension: a propensity-matched analysis. Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:5 Topics: Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Perindopril; Propensity Score; Ramipril; Retrospective Studies; Risk Factors; Telmisartan; Tetrazoles	2015
Safety and effectiveness of a fixed-dose combination of olmesartan, amlodipine, and hydrochlorothiazide in clinical practice. Vascular health and risk management, 2015, Volume: 11 Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Austria; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Primary Health Care; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome	2015
[Optimizing antihypertensive therapy]. MMW Fortschritte der Medizin, 2015, Feb-19, Volume: 157, Issue:3 Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metabolic Syndrome; Randomized Controlled Trials as Topic; Tetrazoles	2015
Simultaneous quantitative analysis of olmesartan, amlodipine and hydrochlorothiazide in their combined dosage form utilizing classical and alternating least squares based chemometric methods. Acta pharmaceutica (Zagreb, Croatia), 2016, Volume: 66, Issue:1 Topics: Amlodipine; Calibration; Dosage Forms; Drug Combinations; Hydrochlorothiazide; Imidazoles; Least-Squares Analysis; Spectrophotometry; Tetrazoles	2016
Single-Pill Triple Fixed Dose Combination Therapy with Single Component Drug Monitoring in Treatment-Resistant Hypertension: A Pilot Study. Current vascular pharmacology, 2018, 01-26, Volume: 16, Issue:2 Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Drug Monitoring; Drug Resistance; Drug Substitution; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Pilot Projects; Tablets; Tetrazoles; Time Factors; Treatment Outcome	2018
Treatment of hypertension in CKD patients with azilsartan/chlorthalidone vs olmesartan/hydrochlorothiazide. Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:4 Topics: Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Oxadiazoles; Renal Insufficiency, Chronic; Tetrazoles	2018
Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Hypertension and Cardiovascular Risk Factors. Advances in therapy, 2023, Volume: 40, Issue:11 Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Female; Heart Disease Risk Factors; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Prospective Studies; Republic of Korea; Risk Factors; Tetrazoles	2023