hydrochlorothiazide and nicardipine

hydrochlorothiazide has been researched along with nicardipine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's4 (21.05)18.2507
2000's6 (31.58)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G; Lorenti, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Huikko, M; Jounela, A; Kanniainen, E; Penttila, O1
Lacourcière, Y; Lévesque, C; Poirier, L; Provencher, P1
Brown, R; Conrad, KA; Fagan, TC; Freedman, D; Lessem, J; Michelson, E; Montijo, M; Schnaper, H; Smolens, P1
Bradley, I; Davis, A; Ganvir, P; Gostick, NK; Hopwood, AM; MacKay, D; Mayhew, SR; Mukerji, D; Shepherd, F1
Lernhardt, E; Solt-Buzsaki, V; Ziegler, MG1
Creytens, G; Saelen, A1
Carver, LA; Lee, CH; Strosberg, AM1
Freslon, JL; Giudicelli, JF; Richer, C1
Arriaga-Gracia, J; González-García, CA; Sánchez-Garcia, JL1
Champion, D; Cook, CA; Ferdinand, KC; Jenkins, PA; Kong, BW; Weir, MR; Wong, S; Wright, JT1
Fukuzawa, M; Miyaguchi, S; Nakazawa, T; Ohta, S; Qiang, X; Sakata, Y; Satoh, J; Takahashi, K; Takizawa, Y; Toyota, T1

Reviews

1 review(s) available for hydrochlorothiazide and nicardipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

8 trial(s) available for hydrochlorothiazide and nicardipine

ArticleYear
A comparative study of nicardipine and pindolol as second-line treatments in essential hypertension.
    The Journal of international medical research, 1992, Volume: 20, Issue:3

    Topics: Adult; Aged; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nicardipine; Pindolol; Posture; Supine Position

1992
Ambulatory blood pressure monitoring for the assessment of nicardipine as a third drug in severe essential hypertension.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:2

    Topics: Adult; Aged; Ambulatory Care; Blood Pressure Determination; Capsules; Captopril; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nicardipine

1992
Nicardipine and hydrochlorothiazide in essential hypertension.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:4

    Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Exercise; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Nicardipine; Posture; Random Allocation; Time Factors

1989
A randomised comparative trial of nicardipine versus amiloride and hydrochlorothiazide in mild to moderate hypertension. A report from the General Practitioner Hypertension Study Group.
    Journal of human hypertension, 1989, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Nicardipine; Random Allocation; Time Factors

1989
Dose response to hydrochlorothiazide in hypertensives receiving a calcium channel blocker.
    Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10, Issue:5

    Topics: Blood Glucose; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nicardipine; Potassium; Uric Acid

1988
Comparative effects of nicardipine hydrochloride and hydrochlorothiazide in the treatment of mild to moderate hypertension: a double-blind parallel study.
    The British journal of clinical practice, 1986, Volume: 40, Issue:12

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nicardipine

1986
Nicardipine or propranolol combined with hydrochlorothiazide in patients with essential hypertension.
    Proceedings of the Western Pharmacology Society, 1993, Volume: 36

    Topics: Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nicardipine; Propranolol

1993
Comparison of the efficacy and metabolic effects of nicardipine and hydrochlorothiazide in hypertensive black men and women.
    Journal of human hypertension, 1993, Volume: 7, Issue:2

    Topics: Adult; Aged; Black People; Blood Glucose; Cholesterol; Creatinine; Double-Blind Method; Female; Homeostasis; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nicardipine; Potassium; Sex Characteristics; Sodium

1993

Other Studies

10 other study(ies) available for hydrochlorothiazide and nicardipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction.
    Journal of medicinal chemistry, 2004, Jul-29, Volume: 47, Issue:16

    Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antihypertensive drugs: their postural hypotensive effect and their blood pressure lowering activity in conscious normotensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 261, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hydrochlorothiazide; Hypotension, Orthostatic; Male; Minoxidil; Nicardipine; Nifedipine; Nitroprusside; Pentolinium Tartrate; Phentolamine; Prazosin; Rats; Rats, Inbred Strains

1983
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
    Paroi arterielle, 1980, Volume: 6, Issue:4

    Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Relationship, Drug; Hydrochlorothiazide; Hypertension; Male; Nicardipine; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents

1980
Modulation of tumor necrosis factor-alpha production with anti-hypertensive drugs.
    Immunopharmacology, 2000, Volume: 48, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Diuretics; Doxazosin; Humans; Hydrochlorothiazide; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Metoprolol; Mice; Mice, Inbred BALB C; Monocytes; Nicardipine; Nitrobenzenes; Piperazines; Sodium Chloride Symporter Inhibitors; Tumor Necrosis Factor-alpha

2000