hydrochlorothiazide and moexipril

hydrochlorothiazide has been researched along with moexipril in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's13 (54.17)18.2507
2000's6 (25.00)29.6817
2010's3 (12.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Hayashi, CM; Lakatos, I; McClelland, DL; Rosenkranz, RP1
Aarsland, T; Dickstein, K; Ferrari, P; Stimpel, M; Todd, M1
Chrysant, SG; Fox, AA; Stimpel, M1
Fox, AA; Stimpel, M; White, WB1
Stimpel, M; White, WB1
Persson, B; Stimpel, M1
Chrysant, SG; Stimpel, M2
Angehrn, JC; Bonn, R; Cawello, W; De Schepper, PJ; Hutt, V; Michaelis, K; Salomon, P; Verbesselt, R1
Koch, B; Stimpel, M1
Jee, WS; Liang, H; Ma, YF; Pun, S; Stimpel, M1
Friehe, H; Gietl, R; Ney, P1
Koch, B; Oparil, S; Stimpel, M1
Koch, B; Stimpel, M; White, WB1
Atmaca, S; Cetin, SM; Ertürk, S1
Chrysant, GS; Chrysant, SG1
Belousov, IuB; Demidova, MA; Leonova, MV; Tarasov, AV1
Andreevskaia, EM; Burkov, SG; Ivleva, AIa1
Elaziz, OA; Farouk, M; Hemdan, A; Shehata, MA; Tawakkol, SM1

Reviews

2 review(s) available for hydrochlorothiazide and moexipril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacological and clinical profile of moexipril: a concise review.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bone and Bones; Diuretics; Drug Combinations; Heart; Humans; Hydrochlorothiazide; Hypertension; Kidney; Liver; Multicenter Studies as Topic; Prodrugs; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines

2004

Trials

12 trial(s) available for hydrochlorothiazide and moexipril

ArticleYear
Comparison of the efficacy of three dose levels of moexipril versus placebo as add-on therapy to hydrochlorothiazide in patients with moderate hypertension.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:2

    Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Tetrahydroisoquinolines

1994
Comparison of moexipril, a new ACE inhibitor, to verapamil-SR as add-on therapy to low dose hydrochlorothiazide in hypertensive patients.
    American journal of hypertension, 1995, Volume: 8, Issue:4 Pt 1

    Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Renin; Tetrahydroisoquinolines; Verapamil

1995
Long-term efficacy and safety of moexipril in the treatment of hypertension.
    Journal of human hypertension, 1994, Volume: 8, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Follow-Up Studies; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Tetrahydroisoquinolines

1994
Long-term safety and efficacy of moexipril alone and in combination with hydrochlorothiazide in elderly patients with hypertension.
    Journal of human hypertension, 1995, Volume: 9, Issue:11

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Prognosis; Tetrahydroisoquinolines

1995
Evaluation of the antihypertensive efficacy and tolerability of moexipril, a new ACE inhibitor, compared to hydrochlorothiazide in elderly patients.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:4

    Topics: Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Prodrugs; Single-Blind Method; Tetrahydroisoquinolines

1996
A comparison of the antihypertensive effectiveness of a combination of moexipril or sustained-release verapamil with low-dose hydrochlorothiazide.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:8

    Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Delayed-Action Preparations; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines; Verapamil

1996
Lack of a pharmacokinetic interaction between moexipril and hydrochlorothiazide.
    European journal of clinical pharmacology, 1996, Volume: 51, Issue:3-4

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Biological Availability; Cross-Over Studies; Diuretics; Drug Interactions; Humans; Hydrochlorothiazide; Isoquinolines; Male; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines

1996
Antihypertensive treatment with moexipril plus HCTZ vs metoprolol plus HCTZ in patients with mild-to-moderate hypertension.
    Journal of human hypertension, 1997, Volume: 11, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Metoprolol; Middle Aged; Tetrahydroisoquinolines

1997
Antihypertensive effectiveness of a very low fixed-dose combination of moexipril and hydrochlorothiazide.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:3

    Topics: Age Factors; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Placebos; Racial Groups; Sex Factors; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines

1998
Antihypertensive treatment in postmenopausal women: results from a prospective, randomized, double-blind, controlled study comparing an ACE inhibitor (moexipril) with a diuretic (hydrochlorothiazide).
    Cardiology, 1998, Volume: 89, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Cholesterol; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Lipids; Middle Aged; Postmenopause; Prospective Studies; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines; Uric Acid

1998
Usefulness of moexipril and hydrochlorothiazide in moderately severe essential hypertension.
    American journal of therapeutics, 1997, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Middle Aged; Prodrugs; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines

1997
[Preventive pharmacotherapy in arterial hypertension: problems of clinical assessment of drugs in women].
    Kardiologiia, 2009, Volume: 49, Issue:7-8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Delayed-Action Preparations; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Tetrahydroisoquinolines; Treatment Outcome

2009

Other Studies

10 other study(ies) available for hydrochlorothiazide and moexipril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Diuretic effects of an ACE inhibitor, RS-10085, and hydrochlorothiazide in the spontaneously hypertensive rat.
    Proceedings of the Western Pharmacology Society, 1989, Volume: 32

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Natriuresis; Rats; Rats, Inbred SHR; Tetrahydroisoquinolines

1989
Impact of antihypertensive therapy on the skeleton: effects of moexipril and hydrochlorothiazide on osteopenia in spontaneously hypertensive ovariectomized rats.
    The Journal of endocrinology, 1997, Volume: 154, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bone and Bones; Bone Diseases, Metabolic; Diuretics; Drug Therapy, Combination; Female; Hydrochlorothiazide; Isoquinolines; Ovariectomy; Rats; Rats, Inbred SHR; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines; Time Factors

1997
Preclinical safety studies of the combination moexipril hydrochloride/hydrochlorothiazide.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Autonomic Nervous System; Cardiovascular System; Central Nervous System; Diuretics; Drug Combinations; Electrolytes; Female; Guinea Pigs; Hemodynamics; Hydrochlorothiazide; Intestinal Mucosa; Intestines; Isoquinolines; Lung; Mice; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Sodium Chloride Symporter Inhibitors; Tetrahydroisoquinolines

1998
Simultaneous determination of moexipril hydrochloride and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods.
    Journal of pharmaceutical and biomedical analysis, 2003, Oct-15, Volume: 33, Issue:3

    Topics: Chromatography, High Pressure Liquid; Hydrochlorothiazide; Spectrophotometry, Ultraviolet; Tablets; Technology, Pharmaceutical; Tetrahydroisoquinolines

2003
[Hypotensive, organoprotective, and metabolic effects of Angiotensin converting enzyme inhibitor moexipril in women with postmenopausal syndrome].
    Kardiologiia, 2006, Volume: 46, Issue:5

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Preparations; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Metabolic Syndrome; Middle Aged; Postmenopause; Syndrome; Tetrahydroisoquinolines; Treatment Outcome; Vasodilation

2006
Comparative study between univariate spectrophotometry and multivariate calibration as analytical tools for simultaneous quantitation of Moexipril and Hydrochlorothiazide.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Dec-10, Volume: 133

    Topics: Antihypertensive Agents; Calibration; Hydrochlorothiazide; Least-Squares Analysis; Limit of Detection; Spectrophotometry; Tablets; Tetrahydroisoquinolines

2014