hydrochlorothiazide has been researched along with methyldopa in 210 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 179 (85.24) | 18.7374 |
| 1990's | 12 (5.71) | 18.2507 |
| 2000's | 8 (3.81) | 29.6817 |
| 2010's | 10 (4.76) | 24.3611 |
| 2020's | 1 (0.48) | 2.80 |
| Authors | Studies |
|---|---|
| Ax, F; Bonham, NM; Hallberg, A; Karlén, A; Lennernäs, H; Winiwarter, S | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dixon, GT; Johnson, ES | 1 |
| Amery, A; Berthaux, P; Bulpitt, C; de Schaepdryver, A; Deruyttere, M; Dollery, C; Fagard, R; Forette, F; Hellemans, J; Lund-Johansen, P; Mutsers, A; Tuomilehto, J | 1 |
| Enger, SC; Helgeland, A; Hjermann, I; Holme, I; Leren, P | 1 |
| Rodman, MJ | 1 |
| Bartolomei, GC; De Giorgio, LA; Innocenti, F | 1 |
| Goldet, L; Jouve, A; Mathieu, M | 1 |
| Amery, A; Berthaux, P; Birkenhäger, W; Bulpitt, C; Clement, D; De Shaepdryver, A; Dollery, C; Ernould, H; Fagard, R; Forette, F; Hellemans, J; Kho, T; Lund-Johansen, P; Meurice, J; Pierquin, L | 1 |
| Friedman, A; Johnston, CI; Suthers, MB; Walter, NM | 1 |
| Amery, A; Berthaux, P; Birkenhäger, W; Boel, A; Brixko, P; Bulpitt, C; Clement, D; de Schaepdryver, A; Deruyttere, M; Dollery, C; Fagard, R; Forette, F; Hellemans, J; Henry, JF; Laaser, U; Lund-Johansen, P; MacFarlane, J; Maling, T; Mutsers, A; Nissinen, A; Ohn, OH; Pelemans, J; Suchettkaye, AI; Tuomilehto, J; Willems, J | 1 |
| Itskovitz, HD; Kochar, MS; Zeller, JR | 1 |
| Amery, A; Berthaux, P; Birkenhäger, W; Boel, A; Brixko, P; Bulpitt, C; Clement, D; De Padua, F; De Schaepdryver, A; Deruyttere, M; Dollery, C; Fagard, R; Forette, F; Forte, J; Hellemans, J; Henry, JF; Koistinen, A; Laaser, U; Lund-Johansen, P; MacFarlane, J; Miguel, P; Mutsers, A; Nissinen, A; Ohm, OT; Pelemans, W; Suchett-Kaye, AI; Tuomilehto, J; Willems, J; Willemse, P | 1 |
| Levine, L | 1 |
| Gomez-Sanchez, CE; Holland, OB; Kuhnert, LV; Pak, CY; Poindexter, C | 1 |
| Jain, AK; McMahon, FG; Ryan, JR | 1 |
| Arias, F; Zamora, J | 1 |
| Fox, LM; Lee, WR; Slotkoff, LM | 1 |
| Barofsky, I; Kresel, JJ | 1 |
| Bernardi, P; Bobba, P; Croce, L; Dalla Torre, M; Di Benedetto, A; Galassi, A; Lombardo, M; Masacci, E; Montemartini, C; Mussari, A; Ricciardi, S; Santucci, F | 1 |
| McAllister, HA; Mullick, FG | 1 |
| Amery, A; Kaufmann, W; Laaser, U; Meurer, KA | 1 |
| Helgeland, A; Hjermann, I; Holme, I; Leren, P | 1 |
| Hollifield, JW; Slaton, PE | 1 |
| Araoye, MA; Freis, ED; Khatri, IM; Yao, LL | 1 |
| Pörsti, P | 1 |
| Kaplan, NM | 1 |
| Bissett, JK; de Soyza, ND; Kane, JJ; Murphy, ML | 1 |
| Glazer, N | 1 |
| Dunn, MI; Freeman, J | 1 |
| Adelman, B; Briggs, WA; Creditor, MA; Lowenthal, DT; Mutterperl, R | 1 |
| Flamm, ES; Goodgold, A; Post, KD; Ransohoff, J | 1 |
| Mirkin, BL; Sinaiko, AR | 1 |
| Burkett, LL; Hamilton, HE; Schwertner, H; Skrdlant, H; Wallace, JE | 1 |
| Hlede, M; Palatini, P; Pessina, AC; Pigato, R | 1 |
| McMahon, FG | 1 |
| Aldrete, JS; Diethelm, AG; Hartley, MW; Morgan, JM; Sterling, WA | 1 |
| Alderman, MH; Schoenbaum, EE | 1 |
| Burg, JR; Dodek, A; Kloster, FR | 1 |
| Ibsen, H; Leth, A | 1 |
| Babaian, AS; Dzhandzhapanian, AZ; Gurgenian, SV; Mikaelian, ES | 1 |
| Van Hoof, R | 1 |
| Amery, A; Birkenhäger, W; Bulpitt, C; Clement, D; de Leeuw, P; de Schaepdryver, A; Deruyterre, ML; Dollery, C; Fagard, R; Fletcher, A | 1 |
| Lutcavage, GJ; Schaberg, SJ | 1 |
| Fletcher, AE | 1 |
| Kusema, T; Mwaluko, GM; Neill, P; Stein, CM | 1 |
| Amery, A; Birkenhäger, W; Bulpitt, C; Clement, D; de Leeuw, P; De Schaepdryver, A; Deruyttere, M; Dollery, C; Fagard, R; Staessen, J | 1 |
| Ambrosioni, E; Cinotti, G; Cuspidi, C; Leonetti, G; Malini, PL; Morabito, S; Pessina, A; Rappelli, A; Sampieri, L; Semplicini, A | 1 |
| España, A; Ledo, A; Soria, C; Torrelo, A | 1 |
| Baume, RM; Croog, SH; Levine, S; Schoenberger, JA; Sudilovsky, A | 1 |
| Diakos, A; Kontoyannis, DA; Kontoyannis, SA; Moulopoulos, SD; Sideris, DA | 1 |
| Amery, A; Birkenhäger, W; Brixko, P; Bulpitt, C; Clement, D; De Schaepdryver, A; Deruyttere, M; Dollery, C; Fagard, R; Forette, F | 1 |
| Helgeland, A; Leren, P | 3 |
| Bulpitt, CJ; Fletcher, AE; Hill, JF | 1 |
| McCormack, P; O'Brien, ET; O'Malley, K | 1 |
| Sullivan, JM | 1 |
| Fidel, J; Glikberg, F | 1 |
| Brown, B; Bulpitt, CJ; Croog, SH; Jenkins, CD; Klerman, GL; Levine, S; Testa, MA; Williams, GH | 1 |
| Bouchard, S; Brookman, S; Farooki, MS; Farsky, K; Lalonde, Y | 1 |
| Alfiero, R; Padula, A; Rizzo, A; Russo, L; Strozzi, C | 1 |
| Garrido Peralta, M; Gras, X; Ocón, J; Oliván, J; Rodicio, JL; Rodríguez Alvarez, J; Ruilope, L; Seco Vasco, J | 1 |
| Dzúrik, R; Dzúriková, V; Krechnáková, A; Szalayová, V | 1 |
| Lavin, PJ; Weissman, BM | 1 |
| Geerling, J | 1 |
| Brunner, HR; Graf, HJ; Jaussi, A; Porchet, M; Rion, F; Waeber, B | 1 |
| Peters, RL; Schweitzer, IL | 1 |
| Khalil, SK; Salama, RB | 1 |
| Sheffield, LT; Sweet, RL | 1 |
| Tarpley, EL | 1 |
| Almeyda, J; Levantine, A | 1 |
| Adlercreutz, H; Castrén, O; Härkönen, M; Raij, K; Saarikoski, S | 1 |
| Freis, ED | 2 |
| Moser, M | 1 |
| O'Malley, TA; Sweet, CS; Wenger, HC | 1 |
| Raper, AJ | 1 |
| McCoubrie, M; Snaith, RP | 1 |
| Bennett, R; Fletcher, HP | 1 |
| Dhasmana, KM; Fokker, WA; Spilker, BA | 1 |
| Lung-Johansen, P | 1 |
| Amery, A; De Schaepdrijver, A | 1 |
| Siegler, RL | 1 |
| de Paula e Silva, P; de Serro-Azul, LG; Saldanha, RV; Veras, RO | 1 |
| Carstens, E | 1 |
| Corman, LA; Skversky, NJ | 1 |
| Freis, ED; Limas, CJ | 1 |
| Kim, KE; Onesti, G; Swartz, C | 1 |
| Finnerty, FA | 1 |
| Alexander, RW; Horwitz, D; Keiser, HR; Lovenberg, W | 1 |
| Naidoo, DN; Seedat, YK | 1 |
| Fishback, DB | 1 |
| Murphy, AV | 1 |
| Ahearn, DJ; Grim, CE | 1 |
| Burke, GE | 1 |
| Froment, A; Froment, R; Zech, P | 1 |
| Macoul, KL; Paris, GL | 1 |
| Spechtmeyer, H | 1 |
| Aoki, VS; Wilson, WR | 1 |
| Conway, J; Sannerstedt, R | 1 |
| Gulati, OD; Munshi, CP; Parikh, HM; Sawkar, LA; Vaidya, PM | 1 |
| Bravo, EL; Dustan, HP; Tarazi, RC | 1 |
| Mendez, MA; Sales, EJ; Villa, JJ | 1 |
| Chu, R | 1 |
| Cruz, HM; Cruz, J; Mattar, E | 1 |
| Smith, RW | 1 |
| de Azambuja, PL | 1 |
| Bargheer, R; Fiegel, G; Heindorf, M | 1 |
| Pasz, T; Schubert, R | 1 |
| Hilden, M; Hilden, T; Leth, A | 1 |
| Mckinney, SE; Peck, HM; Sher, SP; Zwickey, RE | 1 |
| Pomerantz, HZ | 2 |
| Glezer, GA | 1 |
| Zanchetti, A | 1 |
| Gervasini, N; Repetto, S; Rezzonico, A | 1 |
| Hyman, C; Maronde, RF; Walsh, JA | 1 |
| Benati, E; Colombo, G; Tolva, D | 1 |
| Conrad, H | 1 |
| Latotzki, H | 1 |
| Blum, J; Gallet, M; Hutinel, P; Tourniaire, A | 1 |
| Parry, EH | 1 |
| Bresnick, GH; Gay, AJ | 1 |
| Cooper, CM; Stanton, HC | 1 |
| Maughan, GB; Shabanah, EH; Toth, A | 1 |
| Ambrosioni, E; Magnani, B; Malini, PL; Strocchi, E | 1 |
| Kramsch, DM; Kulaga, SF; Walker, JF | 1 |
| Coull, A; Goodman, C; Rosendorff, C | 1 |
| Halawa, B | 2 |
| Richter, R | 1 |
| Helgeland, A | 2 |
| Chandler, T; Franklin, BB; Muhammad, A; Plappert, T; Reichek, N; St John Sutton, M | 1 |
| Blumenstein, BA; Cotsonis, GA; Douglas, MB; Felner, JM; Hall, WD; Knudtson, ML; Porter, VD; Schlant, RC; Unger, DJ; Wollam, GL | 1 |
| Drayer, JI; Gardin, JM; Lipson, JL; Weber, MA | 1 |
| Hilewitz, H; Rogel, S; Weinstein, M | 1 |
| Chernow, B; Coleman, MD; Lake, CR; Zaloga, GP; Ziegler, MG | 1 |
| Amery, A; Beard, K; Birkenhäger, W; Bogaert, M; Brixko, P; Bulpitt, C; Clement, D; de Leeuw, P; De Plaen, JF; Deruyettere, M | 1 |
| Moyer, JH | 1 |
| Bolzano, K; Krempler, F; Sandhofer, F | 1 |
| Hancock, EW | 1 |
| Vaicaitis, JS | 1 |
| Boyles, PW | 1 |
| Godfrey, JC; Neiss, ES; Noble, RE; Vukovich, RA; Webb, EL; Zisblatt, M | 1 |
| Abdel Al, AA; Elsorady, SS; Kamel, SM; Latif, IL; Nayel, SA; Sayed, WS | 1 |
| Ting, S | 1 |
| Obel, AO | 1 |
| Lipson, LG | 1 |
| Eide, I; Foss, OP; Helgeland, A; Kjeldsen, S; Leren, P | 1 |
| Eninia, GI; Godlevska, MA; Smeltere, ES; Uzulinia, IP | 1 |
| Foss, OP; Helgeland, A; Hjermann, I; Holme, I; Leren, P; Lund-Larsen, PG | 1 |
| Beck, ML; Cline, JF; Davis, JW; Hardman, JT; Racela, LS | 1 |
| Gruppillo, P; Tomaini, MD | 1 |
| Hagelund, CH; Tretli, S | 1 |
| Hwang, IK; Moncloa, F; Muccilli, AC | 1 |
| Russell, R; Sova-Schultz, K; Walker, WG; Whelton, PK; Wyndham, R | 1 |
| Brady, JP; Cohen, M; Crits-Christoph, P; Kron, RE; Levy, L; Luborsky, L; Weiss, T | 1 |
| Cervoni, P; Chan, PS; Ronsberg, MA | 1 |
| Gonasun, LM; Langrall, H | 1 |
| MacFarlane, JP | 1 |
| Bonzi, G; Gobbi, A; Reguzzoni, G | 2 |
| Weishar, C | 1 |
| McCrory, WW | 1 |
| Amery, A; Birkenhäger, W; Bogaert, M; Brixko, P; Bulpitt, C; Clement, D; De Leeuw, P; De Plaen, JF; De Schaepdryver, A; Deruyttere, M; Fagard, R; Forette, F; Forte, J; Hamdy, R; Hellemans, J; Henry, JF; Koistinen, A; Laaser, U; Laher, M; Leonetti, G; Lewis, P; Lund-Johansen, P; MacFarlane, J; Meurer, K; Miguel, P; Morris, J; Mutsers, A; Nissinen, A; O'Brien, E; O'Malley, K; Ohm, OJ; Pelemans, W; Perera, N; Tuomilehto, J; Verschueren, LJ; Willemse, P; Williams, B; Zanchetti, A | 1 |
| Beretta, R; Cassi, E; Colombo, A; De Paoli, A; Marciandi, C; Renzetti, GA | 1 |
| Ambrosioni, E; Costa, FV; Magnani, B; Montebugnoli, L; Piovaccari, GC | 1 |
| Boehringer, K; Meier, A; Mordasini, R; Riesen, W; Schiffl, H; Weidmann, P | 1 |
| Garratty, G; Houston, M; Petz, LD; Webb, M | 1 |
| Assandri, J; Cobelli, F; Opasich, C; Vecchio, C | 1 |
| Adlin, EV; Channick, BJ; Kessler, WB; Marks, AD | 1 |
| Lochaya, S; Suvachittanont, O; Thongmitr, V | 1 |
| Dal Palù, C; Hlede, M; Palatini, P; Pessina, AC; Pigato, R | 1 |
| Hall, DR; Odendaal, HJ | 1 |
| Agatonovic-Kustrin, S; Minic, D; Zecević, M; Zivanović, L | 1 |
| Candy, G; Libhaber, E; Radevski, I; Sareli, P; Skudicky, D; Staessen, JA; Thijs, L; Tshele, E; Valtchanova, Z; Wang, JG | 1 |
| OKUN, R; TETREAULT, L; WILSON, WR | 1 |
| AGNEW, TM; IRVINE, RO; NORTH, JD | 1 |
| KINOSHITA, Y; YAMADA, A | 1 |
| CHERIELIGNIERE, EL; DIMARCO, N; GIRALDI, A | 1 |
| FRATTI, L; MONTEMARTINI, C | 1 |
| BOETTIGER, LE; MALMBORG, RO; MICHAELI, EW | 1 |
| CHUPKOVICH, V; FINNERTY, FA; KAKAVIATOS, N | 1 |
| CONTI, LA; DELZAR, L; PALENCIA, AE; URRIBARRI, R | 1 |
| CONTI, LA; DELZAR, LE; PALENCIA, AE; URRIBARRI, R | 1 |
| COLWILL, JM; DUTTON, AM; MORRISSEY, J; YU, PN | 1 |
| FRITEL, D; MILLIEZ, P; REY, LP | 1 |
| BREST, AN; HEIDER, C; MOYER, JH; ONESTI, G; SELLER, RH | 1 |
| SUTTON, D | 1 |
| CHAZAN, JA; KLAPPER, MS; RICHARD, L | 1 |
| FORTIER, J; MORIN, Y; TURMEL, L | 1 |
| KLEIN, K; SIEDEK, H | 1 |
| Ofor, OO | 1 |
| Agbani, EO; Bolaji, EE; Erhun, WO | 1 |
| Aderibigbe, A; Anisiuba, BC; Ba, SA; Boombhi, HJ; Ijoma, CK; Kamdem, MK; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, AN; Omotoso, BA; Richart, T; Staessen, JA; Thijs, L; Ulasi, II | 1 |
| Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM | 1 |
10 review(s) available for hydrochlorothiazide and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Reported ocular side effects of the ten most frequently prescribed drugs.
Topics: Acetaminophen; Ampicillin; Brompheniramine; Codeine; Diazepam; Digoxin; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Eye; Eye Diseases; Female; Furosemide; Humans; Hydrochlorothiazide; Methyldopa; Phenylephrine; Phenylpropanolamine; Pregnancy; Propranolol; Tetracyclines; Triamterene | 1979 |
Drug reactions. XVI. Lichenoid drug eruptions.
Topics: Aminosalicylic Acids; Aniline Compounds; Arsphenamine; Chlorothiazide; Chlorpropamide; Dermatitis, Exfoliative; Gold; Humans; Hydrochlorothiazide; Lichen Planus; Methyldopa; Phenothiazines; Phenylbutazone; Quinacrine; Quinidine; Tetracycline; Thiazoles | 1971 |
Effectiveness of drug therapy in hypertension: present status. A review.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Blockers; Guanethidine; Heart Failure; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Myocardial Infarction; Placebos; Prognosis; Reserpine; Retina; Uremia | 1971 |
The treatment of hypertension. Why, when and how.
Topics: Arteriosclerosis; Cardiovascular Diseases; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Phytotherapy; Plants, Medicinal; Prospective Studies; Rauwolfia; Reserpine; Time Factors | 1972 |
[Use and abuse of antihypertensive drugs in the treatment of elderly patients].
Topics: Age Factors; Aged; Antihypertensive Agents; Cardiac Output; Diuretics; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Methods; Methyldopa; Phytotherapy; Plants, Medicinal; Potassium; Rauwolfia; Sex Factors; Sodium; Time Factors; Vascular Resistance | 1970 |
[Current treatment of hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Phthalazines; Reserpine | 1980 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa; Patient Compliance; Prazosin; Proteinuria; Renin-Angiotensin System; Reserpine; Spironolactone | 1984 |
[Treatment of arterial hypertension in elderly patients].
Topics: Age Factors; Aged; Antihypertensive Agents; Chlorpromazine; Diazoxide; Dihydralazine; Drug Therapy, Combination; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Spironolactone | 1981 |
[ANTIHYPERTENSIVE DRUGS].
Topics: Antihypertensive Agents; Bretylium Compounds; Chlorothiazide; Ganglionic Blockers; Guanethidine; Hydralazine; Hydrochlorothiazide; Hydroflumethiazide; Methyldopa; Rauwolfia; Sympatholytics; Trichlormethiazide; Veratrum; Veratrum Alkaloids | 1963 |
65 trial(s) available for hydrochlorothiazide and methyldopa
| Article | Year |
|---|---|
Glucose intolerance during diuretic therapy. Results of trial by the European Working Party on Hypertension in the Elderly.
Topics: Aged; Blood Glucose; Clinical Trials as Topic; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Hypokalemia; Male; Methyldopa; Middle Aged; Placebos; Research Design; Triamterene | 1978 |
HDL-cholesterol in antihypertensive treatment. The Oslo Study.
Topics: Adult; Antihypertensive Agents; Cholesterol; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins, HDL; Male; Methyldopa; Middle Aged; Propranolol | 1979 |
Results of a national therapeutic trial conducted in 10,000 hypertensive patients by 2000 general practitioners.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Timolol | 1978 |
Antihypertensive therapy in elderly patients. Pilot trial of the European Working Party on High Blood Pressure in the Elderly.
Topics: Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Potassium; Sodium; Triamterene; Uric Acid | 1977 |
A comparison between spironolactone and hydrochlorothiazide with and without alpha-methyldopa in the treatment of hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Renin; Spironolactone | 1978 |
Antihypertensive therapy in patients above age 60. Third interim report of the European Working Party on High blood pressure in Elderly (EWPHE).
Topics: Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Double-Blind Method; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Random Allocation; Sodium; Triamterene; Uric Acid | 1978 |
Prazosin in hypertension with and without methyldopa.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Prazosin; Quinazolines | 1979 |
Antihypertensive therapy in patients above age 60 years (Fourth Interim report of the European Working Party on High Blood pressure in Elderly: EWPHE).
Topics: Aged; Aging; Blood Glucose; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Time Factors; Triamterene; Uric Acid | 1978 |
Antihypertensive comparison of furosemide with hydrochlorothiazide for black patients.
Topics: Adult; Aged; Black or African American; Clinical Trials as Topic; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Parathyroid Hormone; Placebos; Potassium; Renin | 1979 |
The hypouricaemic effect of tienilic acid: experience in patients with hyperuricaemia.
Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Drug Administration Schedule; Female; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Probenecid; Ticrynafen; Uric Acid | 1979 |
Effects of antihypertensive therapy on cardiovascular response to exercise.
Topics: Adult; Blood Pressure; Diastole; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Physical Exertion; Systole | 1979 |
[Whether treatment of hypertension in elderly patients is necessary: a European study (author's transl)].
Topics: Age Factors; Aged; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Pilot Projects; Placebos; Triamterene | 1978 |
A comparison of debrisoquine and methyldopa in hypertension.
Topics: Adult; Clinical Trials as Topic; Debrisoquin; Female; Humans; Hydrochlorothiazide; Hypertension; Isoquinolines; Male; Methyldopa; Middle Aged; Placebos | 1976 |
Antihypertensive drugs in combination: Effects of methyldopa on thiazide-induced changes in renal hemodynamics and plasma renin activity.
Topics: Adult; Blood Pressure; Chlorothiazide; Clinical Trials as Topic; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Kidney; Methyldopa; Middle Aged; Renin | 1975 |
Comparison of guanethidine and methyldopa in essential hypertension: a controlled study.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pulse | 1975 |
Moderate hypertension: treatment with guanethidine and methyldopa.
Topics: Adult; Body Weight; Clinical Trials as Topic; Drug Administration Schedule; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Posture; Time Factors | 1975 |
Patient compliance for antihypertensive medication: the usefulness of urine assays.
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Patient Compliance | 1976 |
Efficacy of an antihypertensive agent. Comparison of methyldopa and hydrochlorothiazide in combination and singly.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methods; Methyldopa; Middle Aged; Placebos; Posture | 1975 |
Left ventricular hypertrophy in elderly hypertensive patients: a report from the European Working Party on High Blood Pressure in the Elderly trial.
Topics: Aged; Cardiomegaly; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Survival Rate; Triamterene | 1991 |
Risks and benefits in the trial of the European Working Party on High Blood Pressure in the Elderly.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Triamterene | 1991 |
Adverse treatment effects in the trial of the European Working Party on High Blood Pressure in the Elderly.
Topics: Aged; Depression; Double-Blind Method; Drug Therapy, Combination; Europe; Gout; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Surveys and Questionnaires; Triamterene | 1991 |
Combination of a thiazide, a vasodilator and reserpine compared with methyldopa plus hydrochlorothiazide in the treatment of hypertension in Zimbabwe.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clopamide; Dihydroergotoxine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Random Allocation; Reserpine | 1990 |
Is a high serum cholesterol level associated with longer survival in elderly hypertensives?
Topics: Aged; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Time Factors; Triamterene | 1990 |
Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study.
Topics: Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Multicenter Studies as Topic; Propranolol; Randomized Controlled Trials as Topic | 1990 |
Self-reported side effects from antihypertensive drugs. A clinical trial. Quality of Life Research Group.
Topics: Adult; Age Factors; Aged; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Educational Status; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Multicenter Studies as Topic; Propranolol; Quality of Life; Random Allocation; United States | 1990 |
Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial.
Topics: Actuarial Analysis; Aged; Antihypertensive Agents; Cardiovascular Diseases; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Random Allocation; Triamterene | 1985 |
Coronary heart disease and treatment of hypertension. Some Oslo Study data.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipid Metabolism; Male; Methyldopa; Middle Aged; Norway; Propranolol; Random Allocation | 1986 |
Oslo Hypertension Study.
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Cholesterol, HDL; Coronary Disease; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Norway; Propranolol; Triglycerides | 1986 |
Angiotensin converting enzyme inhibitors and quality of life: the European trial.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Prospective Studies; Quality of Life; Random Allocation | 1985 |
Isolated systolic hypertension: data from the European Working Party on High Blood Pressure in the Elderly.
Topics: Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Multicenter Studies as Topic; Random Allocation; Systole; Triamterene | 1988 |
Oslo study: treatment of mild hypertension. A five-year controlled drug study.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Propranolol | 1987 |
The effects of antihypertensive therapy on the quality of life.
Topics: Adult; Aged; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Quality of Life; Random Allocation | 1986 |
Comparison of once-daily guanfacine and twice-a-day methyldopa in the treatment of mild to moderate hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Guanfacine; Guanidines; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Phenylacetates; Random Allocation; Time Factors | 1985 |
[Multicenter study of the efficacy of 3 antihypertensive regimens: captopril + hydrochlorothiazide, oxprenolol + hydrochlorothiazide, and alphamethyldopa + hydrochlorothiazide].
Topics: Adult; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Prospective Studies; Spain | 1985 |
[Usefulness of ambulatory registration of arterial pressure in therapeutic trials of antihypertensive agents].
Topics: Adult; Aged; Ambulatory Care; Amiloride; Antihypertensive Agents; Blood Pressure Determination; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Private Practice; Timolol | 1985 |
Controlled trial of guanethidine and methyldopa in moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Guanethidine; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Time Factors | 1974 |
Haemodynamic changes in long-term therapy of essential hypertension: a comparative study of diuretics, alpha-methyldopa and clonidine.
Topics: Adult; Cardiac Output; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Polythiazide; Vascular Resistance | 1973 |
European working party on high blood pressure in elderly (EWPHE): organization of a double-blind multicentre trial on antihypertensive therapy in elderly patients.
Topics: Age Factors; Aged; Antihypertensive Agents; Belgium; Cardiovascular Diseases; Clinical Trials as Topic; England; Female; France; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Netherlands; Norway; Organization and Administration; Placebos; Triamterene | 1973 |
Hypertension: effectiveness of two drugs.
Topics: Antihypertensive Agents; Benzothiadiazines; Clinical Trials as Topic; Diuretics; Enzyme Therapy; Humans; Hydrochlorothiazide; Hypertension; Methyclothiazide; Methyldopa; Monoamine Oxidase Inhibitors; Pargyline | 1967 |
[Clinical methods on the demonstration of the action of antihypertensive agents].
Topics: Antihypertensive Agents; Cardiovascular System; Clinical Trials as Topic; Electrocardiography; Endocrine Glands; Guanethidine; Heart Function Tests; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Kidney Function Tests; Liver Function Tests; Methyldopa; Placebos; Radiography; Reserpine | 1969 |
Hydralazine and methyldopa in thiazide-treated hypertensive patients.
Topics: Black People; Clinical Trials as Topic; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Placebos; White People | 1970 |
A clinical trial of alpha-methyldopa (Aldomet) and hydrochlorthiazide (Dichlotride) alone and in combination in hypertension.
Topics: Adult; Clinical Trials as Topic; Drug Interactions; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Methyldopa; Middle Aged | 1971 |
[Comparative clinical experimental studies with pure alpha-methyldopa and in combination with hydrochlorothiazide].
Topics: Clinical Trials as Topic; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa | 1965 |
[Comparative mass studies on alpha-methyldopa (Presinol), Sali-Presinol and Cyclazenine in hypertensives of various origin].
Topics: Adult; Aged; Clinical Trials as Topic; Female; Guanine; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Middle Aged | 1965 |
Long-term antihypertensive, metabolic and cellular effects of enalapril.
Topics: Adult; Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Enalapril; Erythrocyte Membrane; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Sodium; Sodium-Potassium-Exchanging ATPase; Uric Acid | 1984 |
The efficacy and safety of enalapril in moderate to severe essential hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Random Allocation; Statistics as Topic | 1984 |
Time course of regression of left ventricular hypertrophy in treated hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Organ Size; Prospective Studies; Random Allocation; Time Factors | 1983 |
The progress of patients in the European Working Party on Hypertension in the Elderly trial.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Triamterene | 1983 |
[A combination of methyldopa, hydrochlorothiazide and amiloride in the treatment of essential hypertension].
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Posture; Pulse; Pyrazines; Urea; Uric Acid | 1984 |
Indapamide in the stepped-care treatment of obese hypertensive patients.
Topics: Adult; Aged; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Male; Methyldopa; Middle Aged; Obesity; Time Factors | 1983 |
A comparison of timolol plus hydrochlorothiazide plus amiloride and methyldopa in essential hypertension in Black Africans.
Topics: Adult; Amiloride; Antihypertensive Agents; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Kenya; Male; Methyldopa; Middle Aged; Pyrazines; Random Allocation; Timolol | 1983 |
Serum glucose levels during long-term observation of treated and untreated men with mild hypertension. The Oslo study.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Body Weight; Drug Therapy, Combination; Fasting; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Random Allocation; Triglycerides | 1984 |
[Clinical study of a new hypotensive drug association].
Topics: Adult; Aged; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1982 |
[Clinical trials with hypertensive patients in general practice].
Topics: Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Random Allocation; Timolol | 1980 |
Treatment of mild hypertension: a five year controlled drug trial. The Oslo study.
Topics: Adult; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Norway; Propranolol; Random Allocation; Time Factors | 1980 |
Multiclinic evaluation of the antihypertensive effect of a methyldopa, hydrochlorothiazine, and amiloride combination.
Topics: Adult; Aged; Amiloride; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Pyrazines; Random Allocation; Time Factors | 1980 |
[Comparative study between prazosin and methyldopa in essential arterial hypertension: results of a parallel, randomized double-blind trial].
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Prazosin; Quinazolines; Random Allocation; Renin | 1980 |
Adverse reactions to pindolol administration.
Topics: Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Pindolol; Propranolol; Random Allocation | 1982 |
Methyldopa in the elderly hypertensive.
Topics: Aged; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Triamterene | 1982 |
Antihypertensive therapy in patients above age 60 with systolic hypertension. A progress report of the European Working Party on High Blood Pressure in the Elderly (EWPHE).
Topics: Aged; Blood Glucose; Blood Pressure; Creatinine; Drug Therapy, Combination; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Methyldopa; Systole; Triamterene; Uric Acid | 1982 |
[The effect of hydrochlorothiazide/amiloride alone or in combination with alpha-methyldopa on serum lipoproteins].
Topics: Adult; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Methyldopa; Pyrazines | 1981 |
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy.
Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Gestational Age; Humans; Hydrochlorothiazide; Hypertension; Length of Stay; Methyldopa; Nifedipine; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Treatment Outcome | 1998 |
Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial.
Topics: Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diastole; Diuretics; Echocardiography; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Methyldopa; Middle Aged; Nifedipine; Patient Compliance; Regression Analysis; South Africa; Systole; Verapamil | 2002 |
Positive benefits of a pharmacist-managed hypertension clinic in Nigeria.
Topics: Aged; Amiloride; Antihypertensive Agents; Community Health Centers; Counseling; Diuretics; Drug Monitoring; Drug Therapy, Combination; Female; Health Services Accessibility; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Nigeria; Patient Education as Topic; Pharmacists; Program Evaluation; Treatment Outcome | 2005 |
Rationale and design of the Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial.
Topics: Adult; Africa South of the Sahara; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Research Design; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
135 other study(ies) available for hydrochlorothiazide and methyldopa
| Article | Year |
|---|---|
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
Topics: Humans; Intestinal Absorption; Jejunum; Models, Biological; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship | 1998 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Efficacy of antihypertensive drugs.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Indoramin; Methyldopa; Models, Biological; Posture | 1976 |
Drug therapy today: how to cope with those new antihypertensive drugs.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hydrochlorothiazide; Methyldopa; Propranolol | 1979 |
[Antihypertensive effectiveness and tolerability of a combination of methyldopa and hydrochlorothiazide with and without potassium supplementation].
Topics: Adult; Aged; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Middle Aged; Potassium | 1979 |
Antihypertensive treatment and pregnancy outcome in patients with mild chronic hypertension.
Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Fetal Growth Retardation; Fetus; Growth; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Infant, Newborn; Methyldopa; Oxytocin; Pregnancy; Pregnancy Complications, Cardiovascular; Prenatal Diagnosis; Ultrasonography | 1979 |
Conditioned saccharin aversion development following administration of hypotensive agents.
Topics: Animals; Antihypertensive Agents; Avoidance Learning; Conditioning, Classical; Drinking; Extinction, Psychological; Hydralazine; Hydrochlorothiazide; Male; Methyldopa; Rats; Saccharin; Taste | 1979 |
[The combination of hydrochlorothiazide, amiloride and alpha-methyldopa in the treatment of arterial hypertension. Clinical evaluation of a multicentric study].
Topics: Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines | 1979 |
Myocarditis associated with methyldopa therapy.
Topics: Adult; Aged; Death, Sudden; Drug Hypersensitivity; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Myocarditis; Myocardium | 1977 |
Possible metabolic side effects of beta-adrenergic blocking drugs.
Topics: Adult; Drug Synergism; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Propranolol; Triglycerides; Uric Acid | 1978 |
Effectiveness of twice-daily dosage of methyldopa in essential hypertension.
Topics: Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Renin | 1978 |
Leukocyte intracellular cations in hypertension: Effect of antihypertensive drugs.
Topics: Adult; Antihypertensive Agents; Electrolytes; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Intracellular Fluid; Leukocytes; Magnesium; Male; Methyldopa; Middle Aged; Potassium; Reserpine; Sodium | 1978 |
Electrophysiology of atropine.
Topics: Adult; Aged; Atrioventricular Node; Atropine; Bundle of His; Bundle-Branch Block; Cardiac Catheterization; Electrocardiography; Electrophysiology; Heart; Heart Atria; Heart Conduction System; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Neural Conduction; Nitroglycerin; Purkinje Fibers; Refractory Period, Electrophysiological; Rheumatic Heart Disease; Tachycardia | 1975 |
Ruptured intracranial aneurysms. Case morbidity and mortality.
Topics: Adult; Aged; Aminocaproic Acid; Cerebral Hemorrhage; Humans; Hydrochlorothiazide; Hypertension; Intracranial Aneurysm; Methyldopa; Middle Aged; Rest; Vascular Surgical Procedures | 1977 |
Management of severe childhood hypertension with minoxidil: a controlled clinical study.
Topics: Adolescent; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Humans; Hydrochlorothiazide; Hypertension; Infant; Infant, Newborn; Methyldopa; Minoxidil; Propranolol; Pyrimidines | 1977 |
Identification of selected antihypertensive drugs by thin-layer chromatography.
Topics: Antihypertensive Agents; Chromatography, Thin Layer; Diuretics; Humans; Hydrochlorothiazide; Methyldopa; Reserpine; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1977 |
[Changes in kidney function during hypotensive treatment].
Topics: Adult; Aged; Clonidine; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Propranolol; Uremia | 1976 |
Treatment of accelerated hypertension and end stage renal failure by bilateral nephrectomy and renal transplantation.
Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Child; Creatinine; Female; Graft Rejection; Guanethidine; Hepatitis; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Kidney; Kidney Transplantation; Male; Methyldopa; Middle Aged; Myocardial Infarction; Nephrectomy; Perfusion; Sepsis; Transplantation, Homologous | 1975 |
Detection and treatment of hypertension at the work site.
Topics: Aged; Allied Health Personnel; Costs and Cost Analysis; Delivery of Health Care; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Labor Unions; Male; Mass Screening; Methyldopa; Middle Aged; New York City; Nurses; Occupational Medicine; Patient Compliance | 1975 |
Systolic time intervals in chronic hypertension: Alterations and response to treatment.
Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Heart; Heart Diseases; Heart Function Tests; Heart Ventricles; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Prognosis | 1975 |
Changes in the ratio of plasma to intersitiial fluid volume during long-term antihypertensive therapy.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Extracellular Space; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Plasma Volume; Propranolol; Triamterene | 1976 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Infusions, Intravenous; Male; Methyldopa; Middle Aged; Nifedipine; Ventricular Function, Left; Verapamil | 1991 |
Bilateral submandibular sialolithiasis and concurrent sialadenitis: a case report.
Topics: Aged; Female; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Salivary Duct Calculi; Salivary Gland Calculi; Sialadenitis; Submandibular Gland Diseases; Tomography, X-Ray Computed | 1991 |
[Erosive lichen of the oral mucosa caused by alphamethyldopa and hydrochlorothiazide].
Topics: Female; Humans; Hydrochlorothiazide; Lichen Planus; Methyldopa; Middle Aged; Mouth Diseases; Mouth Mucosa | 1990 |
Antihypertensive treatment for the management of premature ventricular complexes. Pilot study.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Infusions, Intravenous; Male; Metaraminol; Methyldopa; Middle Aged; Nitroprusside | 1988 |
Elevated blood pressure during pregnancy.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Nitroprusside; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Rest | 1986 |
The effect of a single daily low dose of methyldopa and K+ sparing diuretic on blood pressure in the elderly.
Topics: Aged; Aged, 80 and over; Amiloride; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1988 |
[Ergometric evaluation of effects of captopril in hypertensive patients with exertion-induced angina].
Topics: Aged; Angina Pectoris; Captopril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1985 |
[Combination of methyldopa and diuretics in the treatment of hypertensive disease].
Topics: Aged; Amiloride; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines | 1985 |
'Bell's palsy' in accelerated hypertension.
Topics: Adult; Drug Therapy, Combination; Facial Paralysis; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Methyldopa | 1985 |
[Hypertension in the elderly].
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Longitudinal Studies; Methyldopa; Middle Aged; Random Allocation; Triamterene | 1985 |
Acute submassive hepatic necrosis due to methyldopa. A case demonstrating possible initiation of chronic liver disease.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Coombs Test; Electrocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Liver; Methyldopa; Middle Aged; Necrosis; Neutrophils; Reserpine | 1974 |
A new colorimetric method for the determination of methyldopa.
Topics: Colorimetry; Hydrochlorothiazide; Methyldopa; Tablets; Thiosemicarbazones | 1974 |
Myocardial infarction after exercise-induced electrocardiographic changes in a patient with variant angina pectoris.
Topics: Amitriptyline; Angina Pectoris; Arteriosclerosis; Catheterization; Diabetes Complications; Electrocardiography; Exercise Test; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Infarction; Nitroglycerin | 1974 |
Urinary cyclic AMP excretion in toxaemia of pregnancy.
Topics: Cyclic AMP; Cyclohexanes; Diazepam; Estriol; Female; Furosemide; Heterocyclic Compounds; Humans; Hydrazines; Hydrochlorothiazide; Isoxsuprine; Mandelic Acids; Methyldopa; Pre-Eclampsia; Pregnancy; Protoveratrines; Pyridazines; Radioimmunoassay; Reserpine | 1973 |
Office management of hypertension.
Topics: Adult; Aged; Ambulatory Care; Drug Therapy, Combination; Female; Follow-Up Studies; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Phytotherapy; Plants, Medicinal; Private Practice; Rauwolfia; Time Factors | 1974 |
Antagonism of hydrochlorothiazide-induced elevations in plasma-renin activity by methyldopa in conscious renal-hypertensive dogs.
Topics: Animals; Blood Pressure; Dogs; Female; Hydrochlorothiazide; Hypertension, Renal; Kidney; Male; Methyldopa; Nephrectomy; Potassium; Renin; Sodium; Time Factors; Venous Pressure | 1974 |
Practical office management of chronic hypertension.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Physician-Patient Relations; Private Practice; Propranolol; Reserpine; Thiazines | 1974 |
Antihypertensive drugs and depression.
Topics: Adult; Aged; Antihypertensive Agents; Bethanidine; Chlorthalidone; Depression; Diuretics; Drug Therapy, Combination; Fatigue; Furosemide; Guanethidine; Humans; Hydrochlorothiazide; Methyldopa; Middle Aged; Phenobarbital; Potassium; Pyrazines; Reserpine; Self-Assessment; Sodium Chloride Symporter Inhibitors; Theobromine | 1974 |
The use of parameters-following in a therapeutics course.
Topics: Curriculum; Education, Pharmacy, Graduate; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Monitoring, Physiologic; Patients | 1974 |
Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cordotomy; Diazoxide; Electric Stimulation; Ergotamine; Guanethidine; Hydrochlorothiazide; Iproniazid; Male; Mecamylamine; Methyldopa; Pargyline; Phenobarbital; Rats; Reserpine; Sympathetic Nervous System; Thiocyanates; Trimethaphan | 1972 |
Malignant hypertension in children; a patient treated with bilateral nephrectomy.
Topics: Blood Pressure; Child; Creatinine; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Kidney Failure, Chronic; Kidney Transplantation; Methyldopa; Nephrectomy; Propranolol; Retinal Detachment; Transplantation, Homologous | 1974 |
[Use of alpha-methyldopa and alpha-methyldopa combined with hydrochlorothiazide in hypertensive patients in ambulatory treatment: comparative study].
Topics: Ambulatory Care; Blood Pressure; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa | 1972 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlorisondamine; Chlorthalidone; Diuretics; Furosemide; Guanethidine; Guanidines; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Mecamylamine; Methyldopa; Pain; Parotid Gland; Pempidine; Phentolamine; Structure-Activity Relationship; Sulfonamides | 1972 |
Methyldopa-hydrochlorothiazide therapy in hypertensive geriatric patients.
Topics: Aged; Blood Pressure; Coombs Test; Diabetic Nephropathies; Drug Combinations; Female; Hemoglobinometry; Humans; Hydrochlorothiazide; Hypertension; Leukocyte Count; Lymphocytes; Male; Methyldopa; Middle Aged; Nausea; Posture; Pulse | 1973 |
Minoxidil in severe hypertension with renal failure. Effect of its addition to conventional antihypertensive drugs.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Evaluation Studies as Topic; Female; Follow-Up Studies; Furosemide; Guanethidine; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertrichosis; Hypotension, Orthostatic; Kidney Failure, Chronic; Male; Methyldopa; Middle Aged; Minoxidil; Nausea; Piperidines; Pyrimidines | 1973 |
Problems in therapy for the hypertensive patient.
Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic Acid; Female; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypertension, Renal; Hypotension, Orthostatic; Male; Methyldopa; Nephrectomy; Phytotherapy; Plants, Medicinal; Posture; Rauwolfia; Spironolactone; Uremia | 1973 |
How to treat arterial hypertension.
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Cooperative Behavior; Diazoxide; Diuretics; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Methyldopa; Physician-Patient Relations; Reserpine; Spironolactone; Sulfonamides; Triamterene | 1973 |
Human serum dopamine- -hydroxylase. Relationship to hypertension and sympathetic activity.
Topics: Adrenal Gland Neoplasms; Adult; Amphetamine; Blood Flow Velocity; Blood Pressure; Dopamine beta-Hydroxylase; Female; Forearm; Guanethidine; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypotension, Orthostatic; Male; Metaraminol; Methyldopa; Middle Aged; Phenols; Pheochromocytoma; Physical Exertion; Rest; Sympathetic Nervous System; Vascular Resistance | 1973 |
Evaluation of amiloride combined with hydrochlorothiazide (Moduretic) in the treatment of hypertension.
Topics: Adult; Aged; Amiloride; Benzothiadiazines; Diuretics; Drug Combinations; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Propranolol; Pyrazines; Urea; Uremia | 1973 |
Fluorescein circulation time and the treatment of hypertension in the aged.
Topics: Adult; Age Factors; Aged; Blood Circulation Time; Blood Pressure; Carbamates; Ethacrynic Acid; Female; Fluoresceins; Furosemide; Glomerular Filtration Rate; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Failure, Chronic; Male; Methyldopa; Middle Aged; Potassium; Reserpine; Spironolactone | 1973 |
Value and toxicity of therapy for idiopathic nephrotic syndrome in the child.
Topics: Anti-Bacterial Agents; Blood Protein Disorders; Child; Chlorothiazide; Cyclophosphamide; Diet, Sodium-Restricted; Dietary Proteins; Ethacrynic Acid; Furosemide; Glucocorticoids; Humans; Hydrochlorothiazide; Hypertension, Renal; Methyldopa; Nephrotic Syndrome; Plasma Substitutes; Rest; Serum Albumin; Spironolactone | 1973 |
Treatment of malignant hypertension with sodium nitroprusside.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Chemical Phenomena; Chemistry; Diazoxide; Drug Resistance; Female; Ferricyanides; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Injections, Intramuscular; Injections, Intravenous; Male; Methyldopa; Middle Aged; Nitric Oxide; Reserpine; Thiocyanates; Time Factors | 1974 |
[Respective roles of hemodynamic or humoral factors and of hypotensive or salidiuretic drugs in the development of essential hypertension].
Topics: Adult; Chlorthalidone; Diet, Sodium-Restricted; Electrocardiography; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Male; Methyldopa; Middle Aged; Prognosis; Reserpine; Sodium; Spironolactone; Sympathectomy | 1965 |
Reversible bullous retinal detachment in chronic renal disease.
Topics: Adult; Angiography; Diet; Female; Fluorescence; Humans; Hydrochlorothiazide; Hypertension, Renal; Hyponatremia; Kidney Failure, Chronic; Kidney Transplantation; Male; Methyldopa; Papilledema; Peritoneal Dialysis; Retinal Detachment; Sodium; Spironolactone; Transplantation, Homologous | 1969 |
Dependence of arterial pressure on intravascular volume in treated hypertensive patients.
Topics: Adult; Aged; Arteries; Blood Pressure; Female; Furosemide; Guanethidine; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Plasma Volume; Propranolol; Spironolactone; Triamterene | 1972 |
[Treatment of essential and nephrogenic hypertension using alpha-methyldopa and alpha-methyldopa+hydrochlorothiazide. Comparative study].
Topics: Administration, Oral; Adult; Aged; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Middle Aged | 1971 |
Collaborative study and ion exchange method for the determination of methyldopa, chlorothiazide, and hydrochlorothiazide in drug mixtures.
Topics: Chlorothiazide; Chromatography, Ion Exchange; Drug Combinations; Evaluation Studies as Topic; Hydrochlorothiazide; Methods; Methyldopa; Quality Control; Spectrophotometry, Ultraviolet | 1971 |
[Evaluation of the antihypertensive action of methyldopa alone or in combination with hydrochlorothiazide].
Topics: Administration, Oral; Adult; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1971 |
Hypertension and oral contraception.
Topics: Adolescent; Adult; Blood Pressure; Blood Pressure Determination; Contraceptives, Oral; Estrogens; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Progestins; Triamterene | 1971 |
[Combined hormone treatment in arterial hypertension].
Topics: Adult; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Testosterone | 1967 |
High haemoglobin values during medical treatment of hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Creatinine; Diuretics; Erythropoietin; Female; Glomerulonephritis; Hematocrit; Hemoglobinometry; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Polycythemia; Polythiazide; Pyelonephritis; Renal Artery Obstruction; Triamterene | 1968 |
The toxicology of combinations of methyldopa and hydrochlorothiazide.
Topics: Animals; Dogs; Drug Synergism; Hydrochlorothiazide; Hypnotics and Sedatives; Methyldopa; Mice; Rats | 1968 |
Fourteen-year survival in a case of malignant hypertension under hypotensive drug therapy.
Topics: Adult; Antihypertensive Agents; Chlorothiazide; Guanethidine; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Male; Mecamylamine; Methyldopa; Pempidine; Pentolinium Tartrate; Phytotherapy; Plants, Medicinal; Rauwolfia | 1968 |
[Effect of hypotensive substances (hypothiazide, guanetidine, alpha-methyldopa) on basic hemodynamic indices].
Topics: Blood Pressure; Blood Volume; Cardiac Output; Cardiovascular System; Guanethidine; Hematocrit; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Kidney; Methyldopa; Vascular Resistance | 1968 |
[Objectives and methods in therapy of essential arterial hypertension].
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Potassium; Reserpine; Triamterene | 1968 |
[Considerations on ambulatory therapy in a group of hypertensive patients].
Topics: Adult; Aged; Ambulatory Care; Carbamates; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Methyldopa; Middle Aged; Reserpine | 1969 |
Hypotensive drug therapy in the management of hypertension.
Topics: Antihypertensive Agents; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Pargyline; Reserpine; Spironolactone | 1969 |
Venous distensibility in essential hypertension.
Topics: Adult; Female; Forearm; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Plethysmography; Posture; Reserpine; Sympathetic Nervous System; Veins | 1969 |
[Hypotensive activity of alpha-methyl-dopa alone and combined with dihydrochloro-thiazide].
Topics: Adult; Aged; Arteriosclerosis; Drug Synergism; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1965 |
[The physical capacity of hypertensive subjects before and after antihypertension therapy].
Topics: Antihypertensive Agents; Disability Evaluation; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Reserpine | 1965 |
[Problems of essential hypertension].
Topics: Blood Circulation; Blood Pressure Determination; Blood Vessels; Diet, Sodium-Restricted; Germany, East; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Potassium; Vascular Resistance | 1965 |
[Treatment of arterial hypertension with an alpha-methyldopa-hydrochlorothiazide combination].
Topics: Adolescent; Adult; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1966 |
The drug management of mild hypertension.
Topics: Adolescent; Adult; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Reserpine | 1966 |
Rubeosis iridis associated with branch retinal arteriolar occlusions.
Topics: Eye Diseases; Heparin; Humans; Hydrochlorothiazide; Iris; Male; Methyldopa; Middle Aged; Radiography; Retinal Vessels | 1967 |
Antihypertensive effects of drugs measured in unanesthetized rats with established adrenal regeneration hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorisondamine; Diazoxide; Female; Guanethidine; Hydralazine; Hydrochlorothiazide; Methyldopa; Plants, Medicinal; Plants, Toxic; Rats; Reserpine; Veratrum | 1967 |
Experiments with pharmacologic sympatholysis in the gravid.
Topics: Adult; Animals; Dogs; Female; Guanethidine; Humans; Hydrochlorothiazide; Methyldopa; Obstetric Labor, Premature; Oxytocin; Phenoxybenzamine; Phentolamine; Pregnancy; Pregnancy Complications; Propranolol; Rabbits; Rats; Reserpine; Tolazoline; Uterus; Vasodilator Agents | 1967 |
Effect of antihypertensive therapy on left ventricular function and myocardial perfusion at rest and during exercise.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Enalapril; Female; Heart; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Physical Exertion; Propranolol; Random Allocation; Stroke Volume | 1984 |
[Antihypertensive therapy in pregnancy].
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular | 1982 |
The impact on serum lipids of combinations of diuretics and beta-blockers and of beta-blockers alone.
Topics: Adrenergic beta-Antagonists; Cholesterol, HDL; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Methyldopa; Propranolol; Triglycerides; Uric Acid | 1984 |
Reversal of left ventricular hypertrophy by antihypertensive therapy.
Topics: Antihypertensive Agents; Cardiomegaly; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Time Factors | 1982 |
Effect of long-term antihypertensive therapy on cardiac anatomy in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Heart Rate; Heart Septum; Humans; Hydrochlorothiazide; Hypertension; Long-Term Care; Male; Methyldopa; Middle Aged; Myocardium | 1983 |
The effect of single-dose methyldopa and diuretic on BP and left ventricular mass.
Topics: Adult; Aged; Amiloride; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Pyrazines; Stroke Volume; Time Factors | 1984 |
Effect of antihypertensive therapy on sympathetic nervous system activity in patients with essential hypertension.
Topics: Antihypertensive Agents; Captopril; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reserpine; Sympathetic Nervous System; Vasodilator Agents | 1984 |
Bigeminal rhythm on multiple cardiac drug therapy.
Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Digoxin; Drug Therapy, Combination; Electrocardiography; Furosemide; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Nitroglycerin; Potassium Chloride; Quinidine | 1984 |
Methyldopa: an agent for the treatment of older patients with isolated systolic hypertension.
Topics: Aged; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1984 |
Hydrochlorothiazide plus methyldopa in the treatment of isolated systolic hypertension in the elderly.
Topics: Aged; Aging; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1984 |
The role of diuretics in EPH gestosis.
Topics: Adolescent; Adult; Diazepam; Diuretics; Female; Humans; Hydrochlorothiazide; Methyldopa; Middle Aged; Pre-Eclampsia; Pregnancy | 1983 |
Liquid chromatographic determination of methyldopa and methyldopa-thiazide combinations in dosage forms.
Topics: Chlorothiazide; Chromatography, Liquid; Drug Combinations; Hydrochlorothiazide; Methyldopa | 1983 |
Treatment of hypertension in diabetic men: problems with sexual dysfunction.
Topics: Antihypertensive Agents; Blood Pressure; Diabetic Angiopathies; Erectile Dysfunction; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Prazosin | 1984 |
Changes in the lipoprotein profile during antihypertensive therapy.
Topics: Antihypertensive Agents; Cholesterol; Humans; Hydrochlorothiazide; Lipoproteins; Methyldopa; Prazosin; Propranolol; Triglycerides; Uric Acid | 1984 |
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clonidine; Drug Combinations; Drug Evaluation; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Intracranial Arteriosclerosis; Methyldopa; Middle Aged; Reserpine; Time Factors | 1984 |
Fatal intravascular immune hemolysis induced by hydrochlorothiazide.
Topics: Anemia, Hemolytic; Antibodies; Drug Interactions; Drug Therapy, Combination; Hemolysis; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1984 |
Behavioral versus pharmacological treatments for essential hypertension--a needed comparison.
Topics: Adult; Behavior Therapy; Biofeedback, Psychology; Blood Pressure; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Physical Exertion; Propranolol; Relaxation Therapy; Stress, Psychological | 1982 |
Studies on the mechanism of the synergistic antihypertensive activity of captopril and hydrochlorothiazide following acute administration in spontaneously hypertensive rats.
Topics: Animals; Captopril; Drug Synergism; Drug Therapy, Combination; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Proline; Rats; Rats, Inbred Strains; Renin | 1982 |
[Hypotensive effect of saluretics].
Topics: Antihypertensive Agents; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Sodium Chloride Symporter Inhibitors; Time Factors | 1982 |
Case study: drug-induced electrolyte changes.
Topics: Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Methyldopa; Middle Aged; Spironolactone; Water-Electrolyte Imbalance | 1982 |
Essential hypertension in childhood.
Topics: Adolescent; Child; Diet, Sodium-Restricted; Electrocardiography; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Obesity; Propranolol | 1982 |
[Treatment of hypertensive states with a combination of alpha-methyldopa and a diuretic].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Middle Aged | 1982 |
[Evaluation of the antihypertensive efficacy of methyldopa (M-Dopa) used alone or in association with thiabutazide].
Topics: Adolescent; Adult; Antihypertensive Agents; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged | 1980 |
Acute immune intravascular hemolysis due to hydrochlorothiazide.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Antibodies; Antigen-Antibody Complex; Blood Group Antigens; Coombs Test; Erythrocyte Aggregation; Humans; Hydrochlorothiazide; Male; Methyldopa; Suicide, Attempted | 1981 |
[The syndrome of hypertension of effort in the rehabilitation of patients with recent myocardial infarct. Problems of drug therapy].
Topics: Amiloride; Antihypertensive Agents; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Infarction; Physical Exertion | 1980 |
[The combined use of alpha-methyldopa and butizide in the treatment of arterial hypertension].
Topics: Adult; Aged; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged | 1981 |
A comparison of chlorthalidone-reserpine and hydrochlorothiazide-methyldopa as step 2 therapy for hypertension.
Topics: Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Reserpine | 1981 |
Antihypertensive effect of BS 100-141, a new central acting antihypertensive agent.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Guanidines; Heart Rate; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Phenylacetates; Propranolol; Time Factors | 1980 |
[Alpha-methyldopa and renal function in arterial hypertension].
Topics: Antihypertensive Agents; Clonidine; Dihydralazine; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Kidney; Kidney Function Tests; Methyldopa; Propranolol | 1980 |
The use of a response surface methodology on HPLC analysis of methyldopa, amiloride and hydrochlorothiazide in tablets.
Topics: Amiloride; Calibration; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Methyldopa; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tablets | 2001 |
METHYLDOPA AND HYDROCHLOROTHIAZIDE IN PRIMARY HYPERTENSION: CONTROLLED CLINICAL TRIAL OF DRUGS SINGLY AND IN COMBINATION.
Topics: Antihypertensive Agents; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Methyldopa | 1963 |
METHYLDOPA AND HYDROCHLOROTHIAZIDE COMPARED WITH RESERPINE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION.
Topics: Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Placebos; Reserpine | 1963 |
[ACTION OF ALPHA-METHYLDOPA IN COMBINATION WITH DIHYDROCHLOROTHIAZIDE ON RENAL HEMODYNAMICS IN HYPERTENSIVE SUBJECTS].
Topics: Antihypertensive Agents; Arteriosclerosis; Blood Circulation; Diuresis; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Kidney; Kidney Function Tests; Methyldopa; Pharmacology; Renal Artery | 1963 |
[THE ASSOCIATION OF ALPHA-METHYL-DOPA WITH DIHYDROCHLOROTHIAZIDE IN THE THERAPY OF ARTERIAL HYPERTENSION].
Topics: Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Methyldopa | 1964 |
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine; Hemiplegia; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Methyldopa; Neurologic Manifestations; Reserpine; Toxicology | 1964 |
COMPARISON OF ALPHA-METHYLDOPA WITH STANDARD ANTIHYPERTENSIVE THERAPY IN MAN.
Topics: Antihypertensive Agents; Blood Pressure Determination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Reserpine; Toxicology; Veratrum | 1964 |
[ACTION OF ALPHA-METHYLDOPA, ALONE AND COMBINED WITH HYDROCHLOROTHIAZIDE, IN THE TREATMENT OF SYSTEMIC ARTERIAL HYPERTENSION].
Topics: Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Methyldopa | 1964 |
[ALPHA-METHYLDOPA, ALPHA-METHYLDOPA AND HYDROCHLOROTHIAZIDE, AND A PLACEBO IN PATIENTS WITH SYSTEMIC ARTERIAL HYPERTENSION: "DOUBLE-BLIND" TEST].
Topics: Antihypertensive Agents; Biomedical Research; Blindness; Double-Blind Method; Hydrochlorothiazide; Hypertension; Methyldopa; Pharmacology; Placebos; Visually Impaired Persons | 1964 |
ALPHA-METHYLDOPA AND HYDROCHLOROTHIAZIDE. A CONTROLLED STUDY OF THEIR COMPARATIVE EFFECTIVENESS AS ANTIHYPERTENSIVE AGENTS.
Topics: Alkaline Phosphatase; Antihypertensive Agents; Aspartate Aminotransferases; Biomedical Research; Blood Chemical Analysis; Clinical Enzyme Tests; Diuretics; Fever; Hydrochlorothiazide; Liver Function Tests; Methyldopa; Selective Serotonin Reuptake Inhibitors; Serotonin; Sleep Wake Disorders; Statistics as Topic; Toxicology; Urine | 1964 |
[CLINICAL TRIAL OF A HYPOTENSIVE DRUG: 3,4-DIHYDROXY-D-L-PHENYLALANINE OR METHYLDOPA].
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Eye Manifestations; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypotension; Hypotension, Orthostatic; Methyldopa; Phenylalanine; Toxicology | 1964 |
COMPARATIVE EFFECTIVENESS OF PARGYLINE AS AN ANTIHYPERTENSIVE AGENT.
Topics: Antihypertensive Agents; Biomedical Research; Drug Therapy; Guanethidine; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Pargyline; Pharmacology; Placebos; Toxicology | 1964 |
ANTI-HYPERTENSIVE EFFECT OF METHYLDOPA WITH HYDROCHLOROTHIAZIDE.
Topics: Antihypertensive Agents; Drug Therapy; Hydrochlorothiazide; Methyldopa; Toxicology | 1964 |
THE USE OF METHYLDOPA IN HYPERTENSION.
Topics: Aspartate Aminotransferases; Biomedical Research; Blood; Blood Urea Nitrogen; Chlorothiazide; Drug Therapy; Hydrochlorothiazide; Hypertension; Methyldopa; Pharmacology; Placebos; Sex; Toxicology; Urea | 1964 |
METHYLDOPA: CLINICAL STUDIES IN ARTERIAL HYPERTENSION.
Topics: Cardiac Output; Chemical and Drug Induced Liver Injury; Drug Therapy; Hemodynamics; Hepatitis; Humans; Hydrochlorothiazide; Hypertension; Hyperthyroidism; Kidney; Methyldopa; Pharmacology; Placebos; Reserpine; Toxicology | 1964 |
[TREATMENT OF HYPERTENSION WITH ALPHA-METHYL-DOPA AND HYDROCHLOROTHIAZIDE].
Topics: Adolescent; Drug Therapy; Humans; Hydrochlorothiazide; Hypertension; Methyldopa | 1965 |
Oral enalapril-hydrochlorothiazide-methyldopa as first line treatment for severe hypertension in Nigerians.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Nigeria; Prospective Studies; Treatment Outcome | 2004 |
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan | 2020 |