hydrochlorothiazide and labetalol

hydrochlorothiazide has been researched along with labetalol in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (37.50)	18.7374
1990's	6 (15.00)	18.2507
2000's	8 (20.00)	29.6817
2010's	10 (25.00)	24.3611
2020's	1 (2.50)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Akamatsu, M	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Apstein, CS; Battinelli, NJ; Bernard, SA; Foster, E; Huntington-Coats, M; Plehn, JF	1
Fraser, I; Howes, L; Kincaid-Smith, PS; Louis, W; MacDonald, G; Matthews, PG; McGrath, BP; Rallings, M; Scheinkestel, C; Whitworth, JA	1
Due, D; Forbes, WP; Jenkins, P; Lucas, C; Mendels, J; Sirgo, MA	1
Due, DL; Sirgo, MA; Toth, PD; Vidt, DG; Weidler, DJ	1
Ahmad, S; Glasser, SP; Lucas, C; Lutz, LJ; Materson, BJ; Morledge, JH; Ramanathan, KB; Saunders, E; Schnaper, HW; Vlachakis, ND	1
Curry, C; Hinds, J; Kong, BW; Medakovic, M; Poland, M; Roper, K; Saunders, E	1
Bleicher, JM; Nugent, CA; Plachetka, JR	1
Blasucci, DJ; Falliers, CJ; Maloy, JW; Medakovic, M; Vrchota, J	1
Burford, JG; Conrad, SA; George, RB; Hudson, L; Light, RW; Manocha, KL	1
Kalbfleisch, JH; Kochar, MS; Tyson, J	1
Burford, JG; Chetty, K; Conrad, SA; George, RB; Hudson, LD; Light, RW; Manocha, K	1
Carr, AA; Flamenbaum, W; Materson, BJ; McMahon, FG; Poland, M; Weber, MA	1
Bengtsson, C	1
Burford, JG; Conrad, SA; George, RB; Kinasewitz, GT; Manocha, K	1
Chetty, KG; Light, RW; Stansbury, DW	1
Frishman, WH; Johnson, BF; Michelson, EL; Poland, MP	1
Bloomfield, SS; Gantt, CL; Lucas, CP; Medakovic, M; Poland, MP	1
Dal Palu, C; Hlede, M; Morandin, F; Palatini, P; Pessina, AC; Rossi, GP; Semplicini, A; Sperti, G	1
de Vries, TW; Heijmans, HS; van der Veer, E	1
Allen, LV; Erickson, MA	1
Harkins, KG; Long, RC; Minor, DS; Wofford, MR	1
Cervenka, L; Chábová, VČ; Husková, Z; Kompanowska-Jezierska, E; Kopkan, L; Kramer, HJ; Kujal, P; Malý, J; Netuka, I; Opočenský, M; Rakušan, D; Sadowski, J; Schejbalová, S; Skaroupková, P; Vaněčková, I; Vaňourková, Z; Vernerová, Z; Walkowska, A	1
Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM	1

Reviews

1 review(s) available for hydrochlorothiazide and labetalol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

14 trial(s) available for hydrochlorothiazide and labetalol

Article	Year
Double-blind study of dilevalol and captopril, both in combination with hydrochlorothiazide, in patients with moderate to severe hypertension. Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:5 Topics: Adult; Aged; Blood Pressure; Body Weight; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged	1990
The effectiveness of labetalol compared to hydrochlorothiazide in hypertensive black patients. Journal of the National Medical Association, 1991, Volume: 83, Issue:10 Topics: Black People; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Lipids; Lipoproteins; Male; Middle Aged; Prospective Studies	1991
Comparison of labetalol and hydrochlorothiazide in elderly patients with hypertension using 24-hour ambulatory blood pressure monitoring. Journal of clinical pharmacology, 1990, Volume: 30, Issue:6 Topics: Aged; Blood Pressure; Blood Pressure Determination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Monitoring, Physiologic; Random Allocation; Risk Factors; Time Factors	1990
Influence of beta 2 agonism and beta 1 and beta 2 antagonism on adverse effects and plasma lipoproteins: results of a multicenter comparison of dilevalol and metoprolol. The American journal of cardiology, 1989, Jun-05, Volume: 63, Issue:19 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Cholesterol; Coronary Disease; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Lipoproteins; Male; Metoprolol; Middle Aged; Multicenter Studies as Topic; Random Allocation; Risk Factors; Supination; Triglycerides	1989
Labetalol and hydrochlorothiazide in hypertension. Labetalol/Hydrochlorothiazide Multicenter Study Group. Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:1 Topics: Administration, Oral; Adult; Aged; Aging; Analysis of Variance; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged; Posture; Random Allocation	1985
Labetalol compared with propranolol in the treatment of black hypertensive patients. Journal of clinical hypertension, 1987, Volume: 3, Issue:3 Topics: Adolescent; Adult; Aged; Black People; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Lipids; Male; Middle Aged; Propranolol; Prospective Studies; Random Allocation	1987
The effects of treatments with labetalol and hydrochlorothiazide on ventilatory function of asthmatic hypertensive patients with demonstrated bronchosensitivity to propranolol. Journal of clinical hypertension, 1985, Volume: 1, Issue:1 Topics: Adolescent; Adult; Aged; Asthma; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged; Respiration	1985
Concomitant therapy with labetalol and hydrochlorothiazide in moderate to moderately severe essential hypertension. Journal of clinical pharmacology, 1985, Volume: 25, Issue:6 Topics: Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Random Allocation	1985
Comparison of the effects of labetalol and hydrochlorothiazide on the ventilatory function of hypertensive patients with asthma and propranolol sensitivity. Chest, 1985, Volume: 88, Issue:6 Topics: Adolescent; Adult; Aged; Asthma; Clinical Trials as Topic; Drug Evaluation; Female; Forced Expiratory Volume; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Respiration	1985
Monotherapy with labetalol compared with propranolol. Differential effects by race. Journal of clinical hypertension, 1985, Volume: 1, Issue:1 Topics: Adult; Aged; Black or African American; Bradycardia; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Humans; Hydrochlorothiazide; Labetalol; Male; Middle Aged; Propranolol; Sexual Dysfunction, Physiological; White People	1985
Effects of labetalol in hypertensive patients with chronic obstructive pulmonary disease. Chest, 1983, Volume: 83, Issue:3 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Exercise Test; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Lung Diseases, Obstructive; Male; Middle Aged; Random Allocation; Spirometry	1983
Comparison of the effects of labetalol and hydrochlorothiazide on the ventilatory function of hypertensive patients with mild chronic obstructive pulmonary disease. The American journal of medicine, 1983, Oct-17, Volume: 75, Issue:4A Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Forced Expiratory Volume; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Lung Diseases, Obstructive; Middle Aged; Respiration; Vital Capacity	1983
Multiclinic comparison of labetalol to metoprolol in treatment of mild to moderate systemic hypertension. The American journal of medicine, 1983, Oct-17, Volume: 75, Issue:4A Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Lipids; Male; Metoprolol; Middle Aged	1983
Step II treatment with labetalol for essential hypertension. The American journal of medicine, 1983, Oct-17, Volume: 75, Issue:4A Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged	1983

Other Studies

25 other study(ies) available for hydrochlorothiazide and labetalol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Regression of left ventricular hypertrophy in "previously untreated" hypertensive blacks after 6 months of blood pressure reduction with alpha- and beta-adrenergic blockade and thiazide therapy. Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:2 Topics: Adult; Aged; Black People; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged	1992
Labetalol in the treatment of elderly patients with mild essential hypertension. The Journal of the American Osteopathic Association, 1988, Volume: 88, Issue:3 Topics: Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Random Allocation	1988
The use of labetalol for the treatment of hypertension in patients with reversible airway obstruction. Journal of clinical hypertension, 1985, Volume: 1, Issue:1 Topics: Airway Resistance; Asthma; Bronchitis; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Hydrochlorothiazide; Hypertension; Labetalol	1985
Impairment of physical performance after treatment with beta blockers and alpha blockers. British medical journal (Clinical research ed.), 1984, Mar-03, Volume: 288, Issue:6418 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alprenolol; Heart Rate; Humans; Hydrochlorothiazide; Labetalol; Male; Metoprolol; Physical Exertion; Pindolol; Prazosin; Propranolol; Running	1984
Intravenous labetalol in severe hypertension. British journal of clinical pharmacology, 1982, Volume: 13, Issue:1 Suppl Topics: Administration, Oral; Amiloride; Ethanolamines; Hydrochlorothiazide; Hypertension; Infusions, Parenteral; Injections, Intravenous; Labetalol; Time Factors	1982
Warfarin embryopathy: patient, possibility, pathogenesis and prognosis. British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:9 Topics: Acenocoumarol; Bone and Bones; Developmental Disabilities; Drug Combinations; Female; Fetal Diseases; Gestational Age; Humans; Hydrochlorothiazide; Infant, Newborn; Labetalol; Lupus Erythematosus, Systemic; Prednisolone; Pregnancy; Pregnancy Complications; Prognosis; Risk Factors	1993
Stability of labetalol hydrochloride, metoprolol tartrate, verapamil hydrochloride, and spironolactone with hydrochlorothiazide in extemporaneously compounded oral liquids. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Oct-01, Volume: 53, Issue:19 Topics: Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diuretics; Dosage Forms; Drug Compounding; Drug Stability; Humans; Hydrochlorothiazide; Labetalol; Metoprolol; Sodium Chloride Symporter Inhibitors; Spironolactone; Suspensions; Verapamil	1996
Hepatocellular necrosis associated with labetalol. Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:4 Topics: Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Female; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Middle Aged; Necrosis	2007
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects? Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:12 Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Creatinine; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Furosemide; Hydrochlorothiazide; Hypertension; Indoles; Kidney Failure, Chronic; Labetalol; Losartan; Proteinuria; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System	2010
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Jun-01, Volume: 1146 Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan	2020