hydrochlorothiazide and isradipine

hydrochlorothiazide has been researched along with isradipine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (15.79)	18.7374
1990's	26 (68.42)	18.2507
2000's	3 (7.89)	29.6817
2010's	3 (7.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bond, MG; Borhani, NO; Brugger, SB; Craven, TE; Flack, J; Khoury, S; Miller, ST; Schnaper, HW	1
McGrath, BP; McNeil, JJ; Silagy, CA	1
Borhani, NO; Brugger, SB; Byington, RP	1
Bannatyne, RE; Lopez, L; Matthews, K; McCarley, D; Quay, G; Stein, GH	1
Bond, MG; Borhani, NO; Buckalew, V; Canossa-Terris, M; Gibbons, ME; Sowers, JR; Worthy, AJ	1
Gaube, S; Gisinger, C; Klauser, R; Küenburg, E; Prager, R; Schernthaner, G; Schnack, C	1
Applegate, WB; Byington, RP	1
Samuel, P	1
Abrams, A; Cutler, R; Hamilton, B; Holtzman, JL; Kirkendall, WM; Matthews, KP; Neri, G; Stein, GH	1
Bond, G; Brugger, S; Byington, R; Flack, JM; Grimm, RH	1
Bond, MG; Enevold, GL; Strickland, HL; Wilmoth, SK	1
Borhani, NA; Byington, RP; Furberg, CD	1
Carr, AA; Gonasun, LM; Nelson, EB; Prisant, LM; Velasquez, MT; Winer, N	1
Hamilton, BP	1
Gonasun, LM; Goodman, RP; Kirkendal, WM; Kontos, HA; Mohanty, PK; Samuel, P; Wright, JT	1
Chin, B; Gonasun, LM; Kirkendall, W; Lieberman, S; Samuel, P; Schaefer, EJ; Schoenfeld, BH	1
Hansson, L; Zanchetti, A	1
Abrams, A; Culter, R; Hamilton, BP; Hamilton, JH; Holtzman, JL; Kirkendall, WM; Matthews, K; Neri, G; Stein, GH	1
Borhani, NO	1
Amery, A; Bielen, E; Fagard, R; Staessen, J; Thijs, L	1
Bartels, DW; Benz, JR; Due, DL; Hall, WD; Kostis, JB; Peng, A; Perry, HM; Sirgo, M; Townsend, RR	1
Bond, MG; Carr, AA; Nichols, FT; Prisant, LM; Sowers, JR; Thompson, WO; Zemel, MB; Zemel, PC	1
Borhani, NO; Byington, RP; Furberg, CD; Gibbons, ME; Sowers, JR	1
Bond, MG; Borhani, NO; Borhani, PA; Buckalew, VM; Canossa-Terris, M; Carr, AA; Kappagoda, T; Mercuri, M; Rocco, MV; Schnaper, HW; Sowers, JR	1
Madren, EM	1
Chase, GA; Cushman, WG; Gottdiener, JS; Gottdiener, PS; Narayan, P; Papademetriou, V; Zachariah, PK	1
Furberg, CD; Pahor, M; Psaty, BM	1
Aalkjaer, C; Lederballe, O; Mulvany, MJ; Schroeder, AP; Sihm, I; Thygesen, K	1
Hietanen, EK; Kantola, IM; Kataja, MJ; Pelttari, LH; Salo, TT	1
Byington, RP; Craven, TE; Furberg, CD; Pahor, M; Sowers, JR	1
Byington, RP; Craven, TE; Furberg, CD; Pahor, M	1
Kantola, I; Pelttari, L; Salo, TM; Viikari, JS; Voipio-Pulkki, LM	1

Reviews

1 review(s) available for hydrochlorothiazide and isradipine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

28 trial(s) available for hydrochlorothiazide and isradipine

Article	Year
MIDAS: hypertension and atherosclerosis. A trial of the effects of antihypertensive drug treatment on atherosclerosis. MIDAS Research Group. Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 3 Topics: Antihypertensive Agents; Arteriosclerosis; Dihydropyridines; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male	1992
Crossover comparison of atenolol, enalapril, hydrochlorothiazide and isradipine for isolated systolic systemic hypertension. The American journal of cardiology, 1992, Nov-15, Volume: 70, Issue:15 Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitors; Double-Blind Method; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male	1992
Multicenter study with isradipine and diuretics against atherosclerosis. US MIDAS Research Group. Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 1 Topics: Arteriosclerosis; Calcium Channel Blockers; Carotid Artery Diseases; Coronary Artery Disease; Diuretics; Electrocardiography; Humans; Hydrochlorothiazide; Insulin; Isradipine; Multicenter Studies as Topic; Pyridines; Quality of Life; Randomized Controlled Trials as Topic; Regional Blood Flow; Research Design	1990
The Multicenter Isradipine/Diuretic Atherosclerosis Study: a study of the antiatherogenic properties of isradipine in hypertensive patients. MIDAS Research Group. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 3 Topics: Adult; Aged; Arteriosclerosis; Calcium Channel Blockers; Carotid Arteries; Dihydropyridines; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Ultrasonography	1991
Metabolic effects of isradipine versus hydrochlorothiazide in diabetes mellitus. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:1 Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Insulin; Insulin Resistance; Insulin Secretion; Isradipine; Male; Middle Aged; Pyridines	1991
MIDAS, the Multicenter Isradipine/Diuretic Atherosclerosis Study. Design features and baseline data. American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 2 Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Blood Pressure; Carotid Arteries; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Pyridines; Sodium Chloride Symporter Inhibitors; Ultrasonography	1991
Effect of isradipine, a new calcium antagonist on the lipid profile in patients with hypertension. Cor et vasa, 1990, Volume: 32, Issue:2 Suppl 1 Topics: Antihypertensive Agents; Apolipoproteins; Calcium Channel Blockers; Cholesterol; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Lipids; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic	1990
Multicenter comparison of once- and twice-daily isradipine to hydrochlorothiazide for the treatment of hypertension in elderly patients. Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:5 Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Pyridines; Sodium	1990
A comparison of antihypertensive drug effects on the progression of extracranial carotid atherosclerosis. The Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS). Drugs, 1990, Volume: 40 Suppl 2 Topics: Adult; Antihypertensive Agents; Arteriosclerosis; Carotid Artery Diseases; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Isradipine; Male; Middle Aged; Pyridines	1990
Multicenter isradipine diuretic atherosclerosis study (MIDAS). Design features. The Midas Research Group. The American journal of medicine, 1989, Apr-17, Volume: 86, Issue:4A Topics: Adult; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Multicenter Studies as Topic; Pyridines; Random Allocation; Risk Factors; Ultrasonography	1989
Isradipine vs propranolol in hydrochlorothiazide-treated hypertensives. A multicenter evaluation. Archives of internal medicine, 1989, Volume: 149, Issue:11 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Multicenter Studies as Topic; Propranolol; Pyridines; Randomized Controlled Trials as Topic	1989
Treatment of essential hypertension with PN 200-110 (isradipine). The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3 Topics: Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Oxadiazoles; Prazosin; Propranolol; Random Allocation; Time Factors	1987
Isradipine (PN 200-110) versus hydrochlorothiazide in mild to moderate hypertension. A multicenter study. American journal of hypertension, 1988, Volume: 1, Issue:3 Pt 3 Topics: Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Pyridines	1988
Effects of isradipine, a new calcium antagonist, versus hydrochlorothiazide on serum lipids and apolipoproteins in patients with systemic hypertension. The American journal of cardiology, 1988, Nov-15, Volume: 62, Issue:16 Topics: Adult; Aged; Apolipoproteins; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Lipids; Male; Middle Aged; Multicenter Studies as Topic; Pyridines; Random Allocation; Time Factors	1988
The antiatherosclerotic effect of calcium antagonists in man--what did MIDAS actually show? Multicenter Isradipine Diuretic Atherosclerosis Study. Blood pressure, 1995, Volume: 4, Issue:3 Topics: Arteriosclerosis; Carotid Arteries; Controlled Clinical Trials as Topic; Humans; Hydrochlorothiazide; Isradipine; Ultrasonography	1995
One year experience of elderly hypertensive patients with isradipine therapy. Journal of human hypertension, 1994, Volume: 8, Issue:12 Topics: Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Middle Aged; Patient Dropouts	1994
MIDAS: rationale, design and descriptive data of trial patients. The MIDAS Research Group. Blood pressure. Supplement, 1994, Volume: 1 Topics: Adult; Aged; Arteriosclerosis; Carotid Arteries; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Reproducibility of Results; Research Design; Tunica Intima; Tunica Media; Ultrasonography	1994
Response of ambulatory blood pressure to antihypertensive therapy guided by clinic pressure. American journal of hypertension, 1993, Volume: 6, Issue:8 Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitors; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Lisinopril; Male; Prospective Studies	1993
Efficacy and safety of atenolol, enalapril, and isradipine in elderly hypertensive women. The American journal of medicine, 1994, Volume: 96, Issue:1 Topics: Aged; Atenolol; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Middle Aged; Potassium; Prospective Studies	1994
Carotid plaque associations among hypertensive patients. Archives of internal medicine, 1993, Feb-22, Volume: 153, Issue:4 Topics: Aged; Arteriosclerosis; Carotid Stenosis; Female; Georgia; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Michigan; Middle Aged; Risk Factors; Ultrasonography	1993
Calcium antagonists and atherosclerosis. The Multicenter Isradipine/Diuretic Atherosclerosis Study. American journal of hypertension, 1993, Volume: 6, Issue:3 Pt 2 Topics: Adult; Aged; Arteriosclerosis; Carotid Arteries; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Treatment Outcome; Ultrasonography	1993
Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS). A randomized controlled trial. JAMA, 1996, Sep-11, Volume: 276, Issue:10 Topics: Aged; Antihypertensive Agents; Arteriosclerosis; Carotid Arteries; Diastole; Disease Progression; Diuretics; Double-Blind Method; Enalapril; Female; Humans; Hydrochlorothiazide; Isradipine; Likelihood Functions; Male; Middle Aged; Regression Analysis; Sodium Chloride Symporter Inhibitors; Systole; Treatment Outcome; Tunica Intima; Ultrasonography; Vasodilator Agents	1996
Hydrochlorothiazide is superior to isradipine for reduction of left ventricular mass: results of a multicenter trial. The Isradipine Study Group. Journal of the American College of Cardiology, 1997, Volume: 30, Issue:7 Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Echocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Isradipine; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Time Factors	1997
Effect of antihypertensive treatment on cardiac and subcutaneous artery structure: a comparison between calcium channel blocker and thiazide-based regimens. American journal of hypertension, 1998, Volume: 11, Issue:3 Pt 1 Topics: Adult; Amiloride; Antihypertensive Agents; Arteries; Buttocks; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Myocardium; Sodium Chloride Symporter Inhibitors	1998
Little effect of ordinary antihypertensive therapy on nocturnal high blood pressure in patients with sleep disordered breathing. American journal of hypertension, 1998, Volume: 11, Issue:3 Pt 1 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Diuretics; Double-Blind Method; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Middle Aged; Sleep Apnea Syndromes; Sodium Chloride Symporter Inhibitors; Treatment Failure	1998
Isradipine in prediabetic hypertensive subjects. Diabetes care, 1998, Volume: 21, Issue:12 Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Disease; Diabetic Angiopathies; Double-Blind Method; Enalapril; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Insulin; Isradipine; Male; Prediabetic State; Time Factors	1998
Isradipine, raised glycosylated haemoglobin, and risk of cardiovascular events. Lancet (London, England), 1997, Oct-11, Volume: 350, Issue:9084 Topics: Arteriosclerosis; Blood Glucose; Calcium Channel Blockers; Cardiovascular Diseases; Carotid Artery Diseases; Diuretics; Glucose Intolerance; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Middle Aged; Risk Factors; Sodium Chloride Symporter Inhibitors	1997
The effect of four different antihypertensive medications on cardiovascular regulation in hypertensive sleep apneic patients--assessment by spectral analysis of heart rate and blood pressure variability. European journal of clinical pharmacology, 1999, Volume: 55, Issue:3 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Autonomic Nervous System; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Enalapril; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Male; Middle Aged; Sleep Apnea Syndromes; Sodium Chloride Symporter Inhibitors	1999

Other Studies

9 other study(ies) available for hydrochlorothiazide and isradipine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Long-term lipid profiles with isradipine and hydrochlorothiazide treatment in elderly hypertensive patients. Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 1 Topics: Aged; Aged, 80 and over; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Lipids; Male; Middle Aged; Prospective Studies; Pyridines	1990
Detection and monitoring of asymptomatic atherosclerosis in clinical trials. The American journal of medicine, 1989, Apr-17, Volume: 86, Issue:4A Topics: Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Carotid Arteries; Humans; Hydrochlorothiazide; Hypertension; Image Processing, Computer-Assisted; Isradipine; Monitoring, Physiologic; Pyridines; Ultrasonography	1989
Vascular events during antihypertensive treatment. The Journal of family practice, 1996, Volume: 43, Issue:6 Topics: Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Carotid Stenosis; Diuretics; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Randomized Controlled Trials as Topic; Reproducibility of Results; Sodium Chloride Symporter Inhibitors	1996
Treatment of hypertensive patients with diabetes. Lancet (London, England), 1998, Mar-07, Volume: 351, Issue:9104 Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Case-Control Studies; Cohort Studies; Diabetes Complications; Enalapril; Fosinopril; Humans; Hydrochlorothiazide; Hypertension; Isradipine; Nisoldipine; Randomized Controlled Trials as Topic	1998