hydrochlorothiazide and ibuprofen

hydrochlorothiazide has been researched along with ibuprofen in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (7.50)	18.7374
1990's	6 (15.00)	18.2507
2000's	16 (40.00)	29.6817
2010's	14 (35.00)	24.3611
2020's	1 (2.50)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Akamatsu, M	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Bryan, DL; Cooper, LW; Lambert, CM; Lehany, AM; McKenney, JM; Wright, JT	1
Gribnau, FW; Koopmans, PP; Thien, T	1
de Jong, PE; Kallenberg, CG; Meyer, S; ter Borg, EJ; van Rijswijk, MH	1
Sanders, LR	1
Clark, BA; Epstein, FH; Rosa, RM; Shannon, RP	1
Goodfriend, TL; Klassen, D; Peterson, CA; Schuna, AA; Young, DY	1
Avorn, J; Beaudet, MP; Choodnovskiy, I; Everitt, DE; Glynn, RJ; Gurwitz, JH; Monane, M	1
Danon, A; Even, L; Hochberg, Z	1
Cook, ME; Thakur, V; Wallin, JD	1
Bhagat, K	1
de la Luz Reus Medina, M; Kumar, V	1
Dan, N; Kahn, JB; Metzger, K; Siegel, SJ; Werner, K; Winey, KI	1
Kuzmanić, M; Pavlicević, I; Rumboldt, M; Rumboldt, Z	1
Barceló, D; Jelić, A; Petrović, M	1
Chu, KR; Jeong, SH; Lee, E; Park, ES	1
Bueters, RR; Klaasen, A; Schreuder, MF; van den Heuvel, LP	1
Hegazy, MA	1

Reviews

1 review(s) available for hydrochlorothiazide and ibuprofen

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

8 trial(s) available for hydrochlorothiazide and ibuprofen

Article	Year
The effect of high-dose short-term ibuprofen on antihypertensive control with hydrochlorothiazide. Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:4 Topics: Adult; Aged; Blood Pressure; Dinoprostone; Double-Blind Method; Drug Administration Schedule; Electrocardiography, Ambulatory; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Middle Aged; Radioimmunoassay; Random Allocation	1989
The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide. European journal of clinical pharmacology, 1987, Volume: 31, Issue:5 Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Diclofenac; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Indenes; Male; Middle Aged; Potassium; Renin; Sulindac	1987
Increased susceptibility to thiazide-induced hyponatremia in the elderly. Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:4 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Creatinine; Diuresis; Female; Humans; Hydrochlorothiazide; Hyponatremia; Ibuprofen; Male; Osmolar Concentration; Prostaglandins; Water	1994
Assessment of blood pressure during treatment with naproxen or ibuprofen in hypertensive patients treated with hydrochlorothiazide. Journal of clinical pharmacology, 1993, Volume: 33, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Diastole; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Male; Middle Aged; Naproxen; Time Factors	1993
The impact of ibuprofen on the efficacy of antihypertensive treatment with hydrochlorothiazide in elderly persons. The journals of gerontology. Series A, Biological sciences and medical sciences, 1996, Volume: 51, Issue:2 Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Male; Middle Aged; Renin	1996
Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs. American journal of hypertension, 1999, Volume: 12, Issue:9 Pt 1 Topics: Acetaminophen; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Butanones; Creatinine; Dinoprostone; Diuretics; Drug Interactions; Drug Therapy, Combination; Female; Fosinopril; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Middle Aged; Nabumetone; Renal Plasma Flow; Sodium; Sodium Chloride Symporter Inhibitors; Sulindac; Thromboxane B2	1999
Effects of non-steroidal anti-inflammatory drugs on hypertension control using angiotensin converting enzyme inhibitors and thiazide diuretics. East African medical journal, 2001, Volume: 78, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Diclofenac; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Lisinopril; Middle Aged; Osteoarthritis; Sulindac; Treatment Outcome	2001
Interaction between antihypertensives and NSAIDs in primary care: a controlled trial. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2008,Fall, Volume: 15, Issue:3 Topics: Acetaminophen; Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Interactions; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Osteoarthritis; Piroxicam; Prospective Studies	2008

Other Studies

31 other study(ies) available for hydrochlorothiazide and ibuprofen

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Indomethacin and ibuprofen-induced reversible acute renal failure in a patient with systemic lupus erythematosus. The Netherlands journal of medicine, 1987, Volume: 30, Issue:3-4 Topics: Acute Kidney Injury; Female; Humans; Hydrochlorothiazide; Ibuprofen; Indomethacin; Lupus Nephritis; Middle Aged; Triamterene	1987
Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene. Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:12 Topics: Acute Kidney Injury; Catecholamines; Cytokines; Eicosanoids; Hormones; Hydrochlorothiazide; Hypertension; Ibuprofen; Kidney; Kidney Tubular Necrosis, Acute; Nephrosclerosis; Osteoarthritis; Physical Exertion; Renal Circulation; Triamterene; Work Capacity Evaluation	1995
Amelioration of polyuria in nephrogenic diabetes insipidus due to aquaporin-2 deficiency. Clinical endocrinology, 1998, Volume: 49, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aquaporin 2; Aquaporin 6; Aquaporins; Child; Child, Preschool; Combined Modality Therapy; Deamino Arginine Vasopressin; Diabetes Insipidus, Nephrogenic; Diet, Sodium-Restricted; Dinoprostone; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Ibuprofen; Infant; Male; Osmolar Concentration; Polyuria; Vasopressins	1998
Evaluation of cellulose II powders as a potential multifunctional excipient in tablet formulations. International journal of pharmaceutics, 2006, Sep-28, Volume: 322, Issue:1-2 Topics: Cellulose; Compressive Strength; Drug Compounding; Excipients; Hydrochlorothiazide; Ibuprofen; Powders; Solubility; Tablets	2006
Effect of drug type on the degradation rate of PLGA matrices. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2006, Volume: 64, Issue:3 Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Aspirin; Biocompatible Materials; Corticosterone; Delayed-Action Preparations; Diffusion; Drug Carriers; Haloperidol; Hydrochlorothiazide; Hydrolysis; Ibuprofen; Kinetics; Lactic Acid; Models, Chemical; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Thiothixene; Time Factors	2006
Multi-residue method for trace level determination of pharmaceuticals in solid samples using pressurized liquid extraction followed by liquid chromatography/quadrupole-linear ion trap mass spectrometry. Talanta, 2009, Nov-15, Volume: 80, Issue:1 Topics: Acetaminophen; Atorvastatin; Chromatography, Liquid; Diclofenac; Geologic Sediments; Heptanoic Acids; Hot Temperature; Hydrochlorothiazide; Ibuprofen; Pharmaceutical Preparations; Pyrroles; Reference Standards; Reproducibility of Results; Rivers; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry	2009
Effect of particle size on the dissolution behaviors of poorly water-soluble drugs. Archives of pharmacal research, 2012, Volume: 35, Issue:7 Topics: Chemistry, Pharmaceutical; Crystallization; Diclofenac; Hydrochlorothiazide; Ibuprofen; Kinetics; Models, Chemical; Particle Size; Solubility; Solvents; Surface Properties; Technology, Pharmaceutical; Water	2012
Effect of NSAIDs and diuretics on nephrogenesis in an ex vivo embryogenic kidney model. Birth defects research. Part B, Developmental and reproductive toxicology, 2013, Volume: 98, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Morphogenetic Protein 7; Diuretics; Female; Fibroblast Growth Factor 8; Furosemide; Gene Expression; Gene Expression Profiling; Glial Cell Line-Derived Neurotrophic Factor; Hydrochlorothiazide; Ibuprofen; Indomethacin; Kidney; Mice; Mice, Inbred ICR; Organ Culture Techniques; Pregnancy; SOX9 Transcription Factor; WT1 Proteins	2013
A novel pure component contribution algorithm (PCCA) for extracting components' contribution from severely overlapped signals; an application to UV-spectrophotometric data. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Volume: 151 Topics: Acetaminophen; Algorithms; Amiloride; Atenolol; Capsules; Hydrochlorothiazide; Ibuprofen; Spectrophotometry, Ultraviolet; Tablets	2015