hydrochlorothiazide and guanabenz

hydrochlorothiazide has been researched along with guanabenz in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faller, B; Wohnsland, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Grundy, S; Kaplan, NM1
Drayer, JI; Weber, MA1
Chiang, ST; Davis, M; Pascucci, VL; Spangler, T; Walker, BR; White, GR1
Buckalew, VM; Eldridge, JC; Strandhoy, J1
McCarron, DA1
Grenfell, RF1
De Ridder, JH; Marchandise, P1
Fairchild, C; Gomez-Sanchez, CE; Holland, OB1
Deitch, MW; Hare, LE; Walker, BR1
Deitch, MW; Gold, JA; Levey, BA; Walker, BR1

Trials

8 trial(s) available for hydrochlorothiazide and guanabenz

ArticleYear
Comparison of the effects of guanabenz and hydrochlorothiazide on plasma lipids.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Adult; Aged; Blood Pressure; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Female; Guanabenz; Guanidines; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Prospective Studies; Random Allocation; Triglycerides

1988
Effects of guanabenz on gastrointestinal absorption of hydrochlorothiazide.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5

    Topics: Adult; Drug Combinations; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Intestinal Absorption; Kinetics; Male

1984
Endocrinologic effects of antihypertensive therapy with guanabenz or hydrochlorothiazide.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5

    Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; Endocrine System Diseases; Female; Glucagon; Growth Hormone; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Prolactin; Radioimmunoassay

1984
Step-one antihypertensive therapy: a comparison of a centrally acting agent and a diuretic.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 5

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Guanabenz; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Risk

1984
Double-blind study of guanabenz acetate in hypertensive patients.
    Southern medical journal, 1983, Volume: 76, Issue:2

    Topics: Adult; Aged; Blood Pressure; Blood Pressure Determination; Clinical Trials as Topic; Double-Blind Method; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Random Allocation; Time Factors

1983
Effect of guanabenz and hydrochlorothiazide on blood pressure and plasma renin activity.
    Journal of clinical pharmacology, 1981, Volume: 21, Issue:4

    Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin

1981
Comparative antihypertensive effects of guanabenz and clonidine.
    The Journal of international medical research, 1982, Volume: 10, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Male; Middle Aged; Pulse; Sleep Stages

1982
Evaluation of guanabenz added to hydrochlorothiazide therapy in hypertension.
    The Journal of international medical research, 1982, Volume: 10, Issue:3

    Topics: Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pulse

1982

Other Studies

8 other study(ies) available for hydrochlorothiazide and guanabenz

ArticleYear
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Treatment of hypertension in the elderly.
    Southern medical journal, 1986, Volume: 79, Issue:3

    Topics: Aged; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Guanabenz; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Retrospective Studies; Systole

1986
Preliminary clinical trial with a new hypotensive, guanabenz, in a group of hypertensive patients.
    Acta cardiologica, 1980, Volume: 35, Issue:5

    Topics: Aged; Amiloride; Blood Pressure; Drug Evaluation; Drug Tolerance; Female; Guanabenz; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1980