hydrochlorothiazide and diazoxide

hydrochlorothiazide has been researched along with diazoxide in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199027 (65.85)18.7374
1990's2 (4.88)18.2507
2000's3 (7.32)29.6817
2010's8 (19.51)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ando, A; Masuhara, H; Mataga, N; Orita, Y; Urakabe, S1
Hudgins, PM; Williams, PB1
Hatano, N; Kadokawa, T; Kuwashima, J; Shimizu, M; Yoshida, K1
Aloof, S; Nemes, LM; Rosenfeld, JB; Traub, YM1
Challoner-Hue, L; Gottstein, JH; Steele, TH1
Chidsey, CA1
Kroneberg, G; Meng, K1
Kaess, H; Losert, W; Senft, G; Sitt, R1
Senft, G2
Schultz, G; Senft, G1
Dhasmana, KM; Fokker, WA; Spilker, BA1
Finnerty, FA1
Foy, JM; Furman, BL1
Ahearn, DJ; Grim, CE1
Neuvonen, PJ1
Cross, RB; Thornton, WM1
Káldor, A; Pogátsa, G1
Bergmann, F; Chaimovitz, M; Gutman, Y; Zerachia, A1
Nabwangu, J; Staquet, M; Wolff, F1
Hall, CE; Hall, O; Holland, OB1
Cooper, CM; Stanton, HC1
Marumo, F; Mishina, T; Shimada, H1
Halawa, B1
Förster, MT; Slegers, JF1
Nakai, T1
Aynsley-Green, A; Dunne, MJ; James, RF; Johnson, PR; Kane, C; Lindley, KJ; Milla, PJ1
GELFAND, MD; OKUN, R; WILSON, WR1
LANGDON, RG; WOLFF, FW1
Rozance, PJ1
Aliaga, S; Chantala, K; Clark, RH; Herring, AH; Hornik, CP; Hughes, R; Laughon, MM; Smith, PB1
den Boogert, WJ; Thus, KA; van der Heyden, JC1
Khadilkar, A; Khadilkar, V; Lad, S; Shah, N1

Reviews

3 review(s) available for hydrochlorothiazide and diazoxide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Treatment of arterial hypertension in elderly patients].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1981, Aug-15, Volume: 34, Issue:16

    Topics: Age Factors; Aged; Antihypertensive Agents; Chlorpromazine; Diazoxide; Dihydralazine; Drug Therapy, Combination; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Spironolactone

1981
Update on neonatal hypoglycemia.
    Current opinion in endocrinology, diabetes, and obesity, 2014, Volume: 21, Issue:1

    Topics: Biosensing Techniques; Blood Glucose; Developmental Disabilities; Diazoxide; Diuretics; Female; Glucose; Humans; Hydrochlorothiazide; Hyperinsulinism; Hypoglycemia; Infant, Newborn; Infant, Premature; Male; Monitoring, Physiologic; Potassium Chloride; Vasodilator Agents

2014

Trials

1 trial(s) available for hydrochlorothiazide and diazoxide

ArticleYear
Clinical and pharmacokinetic studies of minoxidil, a new antihypertensive agent.
    Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1

    Topics: Adrenergic beta-Antagonists; Amino Alcohols; Antihypertensive Agents; Carbon Isotopes; Clinical Trials as Topic; Diazoxide; Drug Combinations; Humans; Hydralazine; Hydrochlorothiazide; Minoxidil; Piperidines; Pyrimidines; Time Factors

1973

Other Studies

37 other study(ies) available for hydrochlorothiazide and diazoxide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Laser photolysis and fluorescence studies on pyrene-thiazide and pyrene-diazoxide systems.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:5

    Topics: Diazoxide; Diuretics; Fluorescence; Hydrochlorothiazide; Lasers; Photolysis; Pyrenes; Sodium Chloride Symporter Inhibitors; Structure-Activity Relationship

1977
Reduction of 14C-norepinephrine metabolism in rabbit aorta by vasodilators.
    Blood vessels, 1976, Volume: 13, Issue:1-2

    Topics: Animals; Aorta; Depression, Chemical; Diazoxide; Ferricyanides; Hydrochlorothiazide; Muscle, Smooth; Nitroglycerin; Nitroprusside; Norepinephrine; Rabbits

1976
7-chloro-3-(4-methyl-1-piperazinyl)-4H-1,2,4-benzothiadiazine-1,1-dioxide, a new antihypertensive agent.
    Experientia, 1977, Jan-15, Volume: 33, Issue:1

    Topics: Animals; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Carbohydrate Metabolism; Depression, Chemical; Diazoxide; Diuresis; Dogs; Hydrochlorothiazide; Hypertension; Male; Potassium; Rats; Sodium; Time Factors

1977
Stimulation of renin secretion by various methods: optional results with hydrochlorothiazide.
    International urology and nephrology, 1976, Volume: 8, Issue:3

    Topics: Adult; Aged; Diazoxide; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Renin; Sodium; Stimulation, Chemical

1976
Function of the isolated spontaneously hypertensive rat kidney after blood pressure reduction.
    Renal physiology, 1985, Volume: 8, Issue:2

    Topics: Animals; Blood Pressure; Diazoxide; Drug Evaluation, Preclinical; Hydralazine; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Kidney; Male; Placebos; Rats; Rats, Inbred SHR; Reserpine

1985
[Studies in the rat on the problem of the diabetogenic effect of saluretics].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Sep-27, Volume: 251, Issue:5

    Topics: Acetazolamide; Animals; Benzothiadiazines; Blood Glucose; Chlorthalidone; Diazoxide; Glucose Tolerance Test; Hydrochlorothiazide; Hyperglycemia; Ouabain; Potassium Chloride; Rats

1965
[The effect of hydrochlorthiazide on the blood sugar-increasing action of diazoxide].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1966, Volume: 253, Issue:3

    Topics: Animals; Antihypertensive Agents; Carbohydrate Metabolism; Diazoxide; Hydrochlorothiazide; Hyperglycemia; Potassium Deficiency; Rats; Spironolactone

1966
[Modification of hormonal and enzymatic regulations of carbohydrate metabolism by using benzothiadiazines].
    Der Internist, 1966, Volume: 7, Issue:8

    Topics: Animals; Antihypertensive Agents; Benzothiadiazines; Blood Glucose; Carbohydrate Metabolism; Chlorothiazide; Diazoxide; Glycogen; Humans; Hydrochlorothiazide; Insulin; Phosphoric Monoester Hydrolases

1966
[Influence of diuretics on 3',5'-AMP-phosphodiesterase].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Acetazolamide; Adenine Nucleotides; Animals; Cattle; Cyclic AMP; Depression, Chemical; Diazoxide; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Kinetics; Myocardium; Phosphoric Monoester Hydrolases

1967
Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cordotomy; Diazoxide; Electric Stimulation; Ergotamine; Guanethidine; Hydrochlorothiazide; Iproniazid; Male; Mecamylamine; Methyldopa; Pargyline; Phenobarbital; Rats; Reserpine; Sympathetic Nervous System; Thiocyanates; Trimethaphan

1972
How to treat arterial hypertension.
    American family physician, 1973, Volume: 7, Issue:4

    Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Cooperative Behavior; Diazoxide; Diuretics; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Methyldopa; Physician-Patient Relations; Reserpine; Spironolactone; Sulfonamides; Triamterene

1973
Effect of single dose administration of diuretics on the blood sugar of alloxan-diabetic mice or mice made hyperglycaemic by the acute administration of diazoxide.
    British journal of pharmacology, 1973, Volume: 47, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diazoxide; Diuresis; Diuretics; Drug Interactions; Ethacrynic Acid; Female; Furosemide; Hydrochlorothiazide; Hyperglycemia; Kidney; Liver Glycogen; Mice; Natriuresis; Nephrectomy; Potassium; Sodium; Time Factors

1973
Treatment of malignant hypertension with sodium nitroprusside.
    Archives of internal medicine, 1974, Volume: 133, Issue:2

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Chemical Phenomena; Chemistry; Diazoxide; Drug Resistance; Female; Ferricyanides; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Injections, Intramuscular; Injections, Intravenous; Male; Methyldopa; Middle Aged; Nitric Oxide; Reserpine; Thiocyanates; Time Factors

1974
Influence of diuretics and diazoxide on ions and vascular reactivity in normotensive and spontaneously hypertensive rats.
    Annales medicinae experimentalis et biologiae Fenniae, 1971, Volume: 49, Issue:3

    Topics: Animals; Blood Pressure; Calcium; Diazoxide; Ethacrynic Acid; Furosemide; Hematocrit; Hydrochlorothiazide; Hypertension; Magnesium; Male; Manometry; Norepinephrine; Organ Size; Potassium; Pressoreceptors; Rats; Sodium

1971
The effect of benzothiadiazine diuretics on the renal concentrating mechanism of the sheep.
    Quarterly journal of experimental physiology and cognate medical sciences, 1966, Volume: 51, Issue:4

    Topics: Absorption; Animals; Bendroflumethiazide; Chlorides; Chlorothiazide; Diazoxide; Hydrochlorothiazide; Hydroflumethiazide; Kidney Tubules; Natriuresis; Potassium; Sheep; Vasopressins; Water-Electrolyte Balance

1966
[Disorders of carbohydrate metabolism following diuretically effective agents].
    Therapeutische Umschau. Revue therapeutique, 1967, Volume: 24, Issue:8

    Topics: Arteriosclerosis; Carbohydrate Metabolism; Chlorothiazide; Diabetes Mellitus; Diazoxide; Furosemide; Humans; Hydrochlorothiazide; Insulin; Pancreatic Diseases; Potassium

1967
[Data on the mechanism of the diabetogenic effect of chlorothiazides].
    Orvosi hetilap, 1967, Dec-31, Volume: 108, Issue:53

    Topics: Animals; Chlorothiazide; Diazoxide; Furosemide; Gluconeogenesis; Hydrochlorothiazide; Hyperglycemia; Liver; Perfusion; Rats

1967
Influence of drugs, implanted into the hypothalamus, on the water consumption of rats.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 159, Issue:1

    Topics: Animals; Behavior, Animal; Diazoxide; Digitoxin; Diuretics; Drinking; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Hypothalamus; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Male; Nephrectomy; Rats; Seizures; Sodium Chloride; Thirst; Water

1968
The effect of thiazides on the blood sugar of alloxanized and suballoxanized rats.
    Metabolism: clinical and experimental, 1965, Volume: 14, Issue:12

    Topics: Animals; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Experimental; Diazoxide; Glucose Tolerance Test; Hydrochlorothiazide; Rats

1965
Acute and chronic influence of diazoxide on adrenal-regeneration hypertension.
    Canadian journal of physiology and pharmacology, 1967, Volume: 45, Issue:3

    Topics: Adrenal Glands; Animals; Blood Pressure; Blood Vessels; Diazoxide; Drinking; Female; Hydrochlorothiazide; Hypertension; Kidney; Myocardium; Organ Size; Potassium; Rats; Regeneration; Sodium; Thymus Gland; Water-Electrolyte Balance

1967
Antihypertensive effects of drugs measured in unanesthetized rats with established adrenal regeneration hypertension.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorisondamine; Diazoxide; Female; Guanethidine; Hydralazine; Hydrochlorothiazide; Methyldopa; Plants, Medicinal; Plants, Toxic; Rats; Reserpine; Veratrum

1967
Effects of diazoxide and hydrochlorothiazide on water permeability and sodium transport in the frog bladder.
    Pharmacology, 1982, Volume: 24, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Biological Transport; Body Water; Diazoxide; Hydrochlorothiazide; Permeability; Rana catesbeiana; Sodium; Urinary Bladder; Vasopressins

1982
Absence of effect of diazoxide on sodium and water handling in the isolated perfused rat kidney.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:2

    Topics: Animals; Body Water; Diazoxide; Glomerular Filtration Rate; Hydrochlorothiazide; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Sodium

1980
Effect of diazoxide on serum and tissue electrolyte levels in rats with deoxycorticosterone acetate-induced hypertension.
    Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:5

    Topics: Animals; Aorta; Blood Pressure; Calcium; Desoxycorticosterone; Diazoxide; Electrolytes; Hydrochlorothiazide; Hypertension; Kidney; Male; Potassium; Rats; Rats, Wistar; Sodium

1994
Therapy for persistent hyperinsulinemic hypoglycemia of infancy. Understanding the responsiveness of beta cells to diazoxide and somatostatin.
    The Journal of clinical investigation, 1997, Oct-01, Volume: 100, Issue:7

    Topics: Blood Glucose; Cell Membrane; Diazoxide; Disease Management; Electrophysiology; Glycosyltransferases; Humans; Hydrochlorothiazide; Hyperinsulinism; Hypoglycemia; Infant, Newborn; Islets of Langerhans; Membrane Proteins; Octreotide; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Repressor Proteins; Saccharomyces cerevisiae Proteins; Somatostatin; Thiadiazines

1997
THE HYPERGLYCEMIC EFFECT OF HYPOTENSIVE DRUGS.
    Journal of chronic diseases, 1964, Volume: 17

    Topics: Antihypertensive Agents; Benzothiadiazines; Black People; Blood Glucose; Diazoxide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hyperglycemia; Hypertension; Infusions, Parenteral; Maryland; Toxicology

1964
CONJOINT CLINIC ON DRUGS AND DIABETES.
    Journal of chronic diseases, 1964, Volume: 17

    Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose; Body Weight; Chlorothiazide; Chlorpropamide; Diabetes Mellitus; Diazoxide; Diuretics; Dogs; Hydrochlorothiazide; Hypertension; Hypophysectomy; Nitrogen; Pharmacology; Placebos; Polythiazide; Potassium; Rats; Research; Tolbutamide; Toxicology; Trichlormethiazide; Urea

1964
Diuretic exposure in premature infants from 1997 to 2011.
    American journal of perinatology, 2015, Volume: 32, Issue:1

    Topics: Acetazolamide; Amiloride; Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Diazoxide; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Female; Furosemide; Humans; Hydrochlorothiazide; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Male; Mannitol; Metolazone; Off-Label Use; Respiration, Artificial; Retrospective Studies; Spironolactone; Thrombocytopenia

2015
Thrombocytopaenia: a serious side effect of diazoxide.
    BMJ case reports, 2019, Sep-11, Volume: 12, Issue:9

    Topics: Antihypertensive Agents; Child, Preschool; Diazoxide; Drug Therapy, Combination; Epistaxis; Hematemesis; Humans; Hydrochlorothiazide; Hyperinsulinism; Male; Rectal Diseases; Thrombocytopenia

2019
Rare association of Beckwith-Wiedemann syndrome with Hirschsprung's disease in an infant with hypoglycemia.
    BMJ case reports, 2020, Apr-26, Volume: 13, Issue:4

    Topics: Beckwith-Wiedemann Syndrome; Combined Modality Therapy; Diazoxide; Female; Hirschsprung Disease; Humans; Hydrochlorothiazide; Hypoglycemia; Infant, Newborn

2020