hydrochlorothiazide and chlorthalidone

hydrochlorothiazide has been researched along with chlorthalidone in 243 studies

Research

Studies (243)

TimeframeStudies, this research(%)All Research%
pre-1990108 (44.44)18.7374
1990's13 (5.35)18.2507
2000's18 (7.41)29.6817
2010's78 (32.10)24.3611
2020's26 (10.70)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Cecchi, A; Scozzafava, A; Supuran, CT; Temperini, C1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Gudbrandsson, T; Hansson, L1
Dalakos, TG; Pinals, RS; Streeten, DH1
Amadeo, A; Currò, F; de Pasquale, C1
Clark, EC; Podolsky, S; Thompson, EJ1
Smith, WM1
Kaltenbach, M; Kober, G; Schäfer, GE; Werner, E1
Alexander, F; Dubb, JW; Familiar, RG; Stote, RM1
Finnerty, FA2
Baer, JE; Beyer, KH1
Balbi, AL; Franco, RJ; Luna, RL; Martin, LC; Sampaio, M1
Cohen, JD1
Black, DM; Cheitlin, MD; Fine, R; Hearst, N; Hulley, SB; Sebastian, A; Seeley, DG; Siegel, D1
Liepinia, DJ; Skarda, IJ; Skards, JV; Vitols, AV; Voita, DU1
Cohen, JD; Hulley, SB; Kuller, LH; Neaton, J1
Mladovan, G; Severin, E1
Glezer, GA; Levinzon, AM2
Cutler, JA; Furberg, CD1
Hengeveld, WL; Schouten, JA; Westerman, RF1
Borhani, N; Caggiula, A; Dunkle, S; Farrier, N; Kuller, L1
Björnberg, A; Gisslén, H1
Tarpley, EL1
Kroneberg, G; Meng, K1
Nieth, H1
Reimold, EW1
Engelmann, K; Petter, A; Schenkel, R1
McCoubrie, M; Snaith, RP1
Dukor, P; Hushak, J; Imhof, PR; Keller, HM; Schumann, G; Wagner, J1
Lung-Johansen, P1
Distler, A1
Jäättelä, A1
Carstens, E1
Ravera, M; Spaziante, B1
Haller, J1
Froment, A; Froment, R; Zech, P1
Ikeda, T1
Selchau, M1
Fichman, MP; Kleeman, CR; Telfer, N; Vorherr, H1
Davidov, M; Finnerty, FA; Mroczek, WJ1
Hallauer, W; Keller, P; Man, NK; Schirmeister, J1
Buccianti, G; Gastaldi, L; Marazzini, L; Rizzato, G1
Lund-Johansen, P1
Holzgreve, H; Loeschke, K1
Dimitrow, D; Stantschew, A1
Fuchs, W; Kallee, E1
Zanchetti, A1
Portmann, B; Robert, M1
Hartmann, F; Heimsoth, V1
Benveniste, D; Henningsen, P1
Sebaoun, J1
Abe, H; Furukawa, T; Orita, Y; Urakabe, S1
Angelo, TL; Mutalik, GS1
Cutilletta, AF; Remenchik, AP; Talso, PJ1
Freis, ED; Sappington, RF1
Eriksson, K1
Foy, JM1
Bufalari, A; Meloni, G1
Kaplan, NM4
Fletcher, R; Freis, ED; Khatri, IM; Papademetriou, V1
Daveloose, D; Labeyrie, E; Leterrier, F; Molle, D; Salesse, R; Viret, J1
Schoeman, HS; Sommers, DK; van Wyk, M1
Beermann, B1
Ambrosioni, E; Borghi, C; Costa, FV1
Haley, RJ; Lewis, SB; Licht, JH; Pugh, B1
Bhigjee, AI; Hoosen, S; Naidoo, K; Neerahoo, RM; Seedat, YK1
Ames, RP; Peacock, PB1
Kleinjans, JC; Smits, JF; Struyker-Boudier, HA; van Essen, H1
Perry, HM1
van Soeren, F1
Joos, C; Kewitz, H; Reinhold-Kourniati, D1
Wester, PO1
Fischer, RG1
Gonasun, LM; Langrall, H1
Navarro, RP; Nuffort, P; O'Brien, DK; Spencer, DL1
Cherchi, A; Pirisi, R; Pisano, MR; Raffo, M; Sau, F; Seguro, C1
Garrett, BN; Kaplan, NM; Ram, CV1
Borba, P; Didier, M; França, P; Santos, A; Tenório, J1
Adlin, EV; Channick, BJ; Kessler, WB; Marks, AD1
Mironneau, C; Mironneau, J; Savineau, JP1
Albanesi Filho, FM; Brandão, AP; Oigman, W1
Heuer, LJ; Osten, H1
Davidson, C; Morgan, DB1
Blackburn, H; Grimm, RH; Hannan, P; Hunninghake, DB; Lenz, K; Leon, AS1
De Lima, MD; Kohlmann, NE; Kohlmann, O; Neves, FA; Ribeiro, AB; Zanella, MT1
van de Wal, BW1
Fenichel, RR; Lipicky, RJ1
Alli, C; Avanzini, F; Bettelli, G; Colombo, F; Corso, R; Mariotti, G; Radice, M; Tognoni, G; Torri, V1
Hatch, M; Vaziri, ND1
Haffner, S; Saliba, P; Siegel, D1
Cushman, WC; Flack, JM1
de Leeuw, PW; Notter, T; Zilles, P1
Anderson, GM; Clark, JP; Gurwitz, JH; Lau, P; Rochon, PA; Shear, NH; Tu, JV1
Bussey, HI; Reese, AM; Talbert, RL1
NICOLE, JC; PULVER, W1
DENTLER, H; FRANK, H1
BOMPIANI, GD; PANVINO, C1
BEISEL, WR; FORSHAM, PH; SMILO, RP1
WEISSEL, W1
ARTNER, J; BRANDSTETTER, F1
BREST, AN; FUCHS, M; MOYER, JH; SELLER, RH; SWARTZ, C1
GROSSI, F1
COMOLI, G; GHIRINGHELLI, L; MADULI, S1
LABADIE, P1
OZDOGAN, E1
DUNLOP, D1
IWAKI, J1
SHUBECK, F; TATUM, HJ1
BAGROS, P1
BOEHM, P; IRMSCHER, K; ZIMMERMANN, H1
BOETTIGER, LE; MALMBORG, RO; MICHAELI, EW1
PLATT, MA1
EARLEY, LE; ORLOFF, J1
REUTTER, F; SCHAUB, F1
CHRISTENSSON, B; GUSTAFSON, A; WESTLING, H1
ROMANI, JD1
STOKES, W1
FRITEL, D; MILLIEZ, P; REY, LP1
RAHMAN, F; SAYNOR, R; STENTIFORD, NH; VEREL, D1
FUJII, R; IWAZU, A; KATO, K; KOBAYASHI, K; SHIBATA, M1
DEGRAFF, AC; FISCH, S; FREUDENTHAL, RR; SPERBER, RJ1
PELTOLA, P1
Carter, BL; Cohen, JD; Ernst, ME1
Landmark, K; Os, I; Toft, I1
Cao, T; Liu, D; Tepel, M; Wang, L; Zhu, S; Zhu, Z1
Bakris, GL; Chua, DY; Elliott, WJ; Khosla, N1
Bergus, GR; Carter, BL; Ernst, ME; Goerdt, CJ; Phillips, BB; Steffensmeier, JJ; Zimmerman, MB1
Mitka, M1
Saklayen, MG1
Basile, JN; Carter, BL; Ernst, ME1
Elliott, WJ; Grimm, RH1
Parra, D; Rosenstein, R1
Chandurkar, NB; Karnik, ND; Pareek, A; Salagre, SB; Zawar, SD1
Andraus, MH; Azevedo, CP; Borges, BC; Borges, NC; Moreira, RF; Moreno, RA; Salvadori, MC1
Fuster, D1
Armanini, D; Fiore, C1
Carter, BL; Ernst, ME; Grimm, RH; Zheng, S1
Kooter, AJ; Smulders, YM1
Reilly, RF; Vigen, R; Weideman, RA1
Flack, JM; Nesbitt, S; Sica, DA1
Bleske, BE; Dorsch, MP; Erickson, SR; Gillespie, BW; Weder, AB1
Handler, J1
Collins, G; Ernst, ME; Grimm, RH; Neaton, JD; Prineas, RJ; Soliman, EZ; Thomas, W1
Ezer, M; Goldman, A; Kountz, DS; Mikhail, J1
Guddati, AK; Holford, TR; Roush, GC3
Carter, BL1
Agarwal, R; Weir, MR1
Chaturvedi, N; Hardy, R; Hughes, AD; Peterzan, MA1
Bakris, GL; Cushman, WC; Kupfer, S; Lloyd, E; Roberts, A; Sica, D; Weber, MA; White, WB2
Allan, GM; Ivers, N; Padwal, RS1
Karadsheh, F; Weir, MR1
Germino, FW1
Bakris, GL; Cushman, WC; Handley, A; Kupfer, S; Sica, D; Song, E; Weber, MA; White, WB1
Ernst, ME; Lund, BC1
Cushman, WC1
Cho, EJ; Choi, KY; Ihm, SH; Jang, SW; Kim, DB; Kim, JH; Kwon, BJ; Youn, HJ1
Athyros, VG; Karagiannis, A; Mikhailidis, DP; Tziomalos, K1
Ferdinand, KC1
Dhalla, IA; Gomes, T; Hellings, C; Juurlink, DN; Mamdani, MM; Nagge, J; Persaud, N; Yao, Z1
Astor, BC; Gundu, V; Jhagroo, RA; Wolfgram, DF1
Basile, JN; Bloch, MJ1
Buddharaju, V; Ernst, ME; Roush, GC1
DiNicolantonio, JJ; Lavie, CJ; O'Keefe, JH1
Badgett, RG1
Donzelli, A1
Cushman, WC; Einhorn, PT; Whelton, PK1
Dhalla, IA; Juurlink, DN; Mamdani, MM1
Brenner, AC; Brenner, MJ; Matthews, KA1
Diniz, R; Ferreira, FF; Reis do Carmo, W1
Barrios, V; Escobar, C1
Cushman, WC; Lederle, FA; Oparil, S1
Rodenburg, EM; Straus, SM; Stricker, BH; Sturkenboom, MC; van Blijderveen, JC; Verhamme, KM; Zietse, R1
Bassett, K; Musini, VM; Nazer, M; Wright, JM1
Jones, T; Kildare, L; Neher, JO; St Anna, L1
Nair, KV; Saseen, JJ; Wilson, L1
Argulian, E; Grossman, E; Messerli, FH1
Ghushchyan, V; Nair, KV; Saseen, JJ1
Abd El-Hady, D; Albishri, HM; Tayeb, RA1
Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Tandon, S1
Bhutani, J; DiNicolantonio, JJ; Lavie, CJ; O'Keefe, JH1
Cooney, D; Milfred-LaForest, S; Rahman, M1
Springer, K1
Barger, B; Handley, A; Lloyd, E; Roberts, A1
Agarwal, MA; Chandurkar, NB; Dharmadhikari, SK; Godbole, AV; Kshirsagar, PP; Kumbla, MM; Mathur, SL; Messerli, FH; Pareek, AK; Sharma, KH1
Bakris, GL; Sternlicht, H1
Harrell, TE; McBee, EC; Spalding, BM; Tschanz, MP1
Chandurkar, NB; Messerli, FH; Pareek, AK1
Brophy, MT; Cushman, WC; Ferguson, RE; Fiore Md, LD; Lederle, FA1
Dave, C; Hwang, AY; Smith, SM1
Asil, S; Atalar, E1
Cao, L; Liang, W; Ma, H; Yan, W; Yang, J1
Barger, B; Cushman, WC; Handley, A; Lloyd, E; Neutel, JM1
Thomopoulos, C1
Beitelshees, AL; Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Datta, S; Gong, Y; Gums, JG; Johnson, JA; Langaee, TY; McDonough, CW; Sá, ACC; Sadee, W; Scherer, SE; Turner, ST; Webb, A1
Abdelfattah, R; Ernst, ME; Kostis, JB; Roush, GC; Sica, DA; Song, S2
van der Merwe, WM1
Bakris, GL; Hisada, M; Juhasz, A; Kupfer, S; Lloyd, E; Oparil, S; Zhao, L1
Bakris, GL; Cushman, WC; Ferdinand, KC; Lloyd, E; Weber, MA; White, WB; Wu, J1
Cuspidi, C; Tadic, M1
Khitan, ZJ; Meadows, C1
Kuusela, PJ1
Dineva, S; Filipova, E; Kalinov, K; Pavlova, V; Uzunova, K; Vekov, T3
Bottino, LG; Ferrari, F; Fuchs, FD; Fuchs, SC; Helal, L; Martins, VM1
Abdelsalam, RA; Haddad, GM; Marghany, KA1
Chen, R; Hripcsak, G; Krumholz, HM; Madigan, D; Pratt, N; Ryan, PB; Schuemie, MJ; Shea, S; Suchard, MA; You, SC1
Messerli, FH; Oparil, S; Roush, GC1
Hripcsak, G; Schuemie, MJ; Shea, S1
Frieden, TR; Moran, AE; Whelton, PK1
Messerli, FH; Roush, GC1
Chrysant, GS; Chrysant, SG1
Bugeja, A; Burns, K; Canney, M; Edwards, C; Hundemer, GL; Knoll, G; Petrcich, W; Sood, MM1
Agrawal, S; Anand, J; Bachani, D; Doshi, M; Gaikwad, VB; Halder, SK; Kinholkar, B; Kumar, DA; Kumbhar, A; Mathur, R; Mehta, S; Sarkar, G; Sharma, A1
Brophy, MT; Cushman, WC; Ferguson, RE; Fiore, LD; Glassman, PA; Hau, C; Ishani, A; Klint, A; Leatherman, SM; Lew, RA; Taylor, AA; Woods, P1
Ernst, ME; Fravel, MA2
Aurit, SJ; Bashir, K; Burns, T; Hilleman, DE; Pirruccello, SJ1
Agarwal, R1
Chapman, AB; Chekka, LMS; Cooper-DeHoff, RM; Gums, JG; Johnson, JA1
Brophy, MT; Cushman, WC; Ferguson, RE; Fiore, LD; Glassman, PA; Hau, C; Huang, GD; Ishani, A; Klint, A; Leatherman, SM; Lew, RA; Taylor, AA; Woods, P1
Liuzzo, G; Volpe, M1
Bavishi, C1
Hausberg, M; Krämer, BK; Kreutz, R; Wenzel, U1
Messerli, FH1
Cushman, WC; Ishani, A; Leatherman, SM1
Zidek, W1
Ebell, MH1
Steurer, J1

Reviews

41 review(s) available for hydrochlorothiazide and chlorthalidone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Importance of the continuity of anti-hypertension treatment in prevention of ischemic cardiovascular diseases: preliminary note. Controlled study of hypertensive patients treated with amiloride associated with hydrochlorothiazide and chlorthalidone].
    Minerva medica, 1978, Jun-23, Volume: 69, Issue:31

    Topics: Adult; Aged; Amiloride; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pyrazines

1978
[Hypertension--diuretics as antihypertensive agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1970, Volume: 28, Issue:4

    Topics: Aged; Antihypertensive Agents; Arthritis; Benzothiadiazines; Blood Pressure; Chlorothiazide; Chlorthalidone; Diabetes Mellitus; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Photosensitivity Disorders; Spironolactone; Triamterene

1970
[Diuretics. 47].
    Pharmazeutische Praxis, 1970, Volume: 9

    Topics: Antihypertensive Agents; Bendroflumethiazide; Chlorothiazide; Chlorthalidone; Clopamide; Dichlorphenamide; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glaucoma; Humans; Hydrochlorothiazide; Hydroflumethiazide; Metyrapone; Respiratory Insufficiency; Spironolactone; Sulfonamides; Triamterene

1970
Aspects on pharmacokinetics of some diuretics.
    Acta pharmacologica et toxicologica, 1984, Volume: 54 Suppl 1

    Topics: Amiloride; Bendroflumethiazide; Bumetanide; Chlorthalidone; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Kinetics; Sodium Chloride Symporter Inhibitors; Spironolactone

1984
Managing diuretic-induced hypokalemia in ambulatory hypertensive patients.
    The Journal of family practice, 1982, Volume: 14, Issue:6

    Topics: Aged; Ambulatory Care; Chlorthalidone; Diuretics; Food; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Potassium Chloride; Sodium Chloride Symporter Inhibitors

1982
Evidence for the efficacy of low-dose diuretic monotherapy.
    The American journal of medicine, 1996, Sep-30, Volume: 101, Issue:3A

    Topics: Chlorthalidone; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Practice Guidelines as Topic; Sodium Chloride Symporter Inhibitors

1996
[2 IMPORTANT SIDE-EFFECTS OF SALURETIC DRUGS: HYPERURICEMIC AND HYPERGLYCEMIC SYNDROMES].
    La Clinica terapeutica, 1963, Sep-15, Volume: 26

    Topics: Acetazolamide; Blood Chemical Analysis; Chlorothiazide; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hyperglycemia; Syndrome; Toxicology; Uric Acid

1963
[MECHANISM OF ACTION AND CLINICAL USE OF DIURETICS].
    Recenti progressi in medicina, 1963, Volume: 35

    Topics: Bendroflumethiazide; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Diuretics; Hydrochlorothiazide; Hydroflumethiazide; Kidney; Kidney Diseases; Mineralocorticoid Receptor Antagonists; Organomercury Compounds; Pharmacology; Physiology; Spironolactone

1963
THIAZIDE DIURETICS.
    Annual review of medicine, 1964, Volume: 15

    Topics: Antihypertensive Agents; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Diabetes Insipidus; Diuretics; Humans; Hydrochlorothiazide; Hydroflumethiazide; Kidney Tubules; Natriuresis; Pharmacology; Potassium Deficiency; Sodium Chloride Symporter Inhibitors; Toxicology; Trichlormethiazide; Water-Electrolyte Balance

1964
Hydrochlorothiazide versus chlorthalidone: evidence supporting their interchangeability.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:1

    Topics: Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors

2004
Are chlorthalidone and hydrochlorothiazide equivalent blood-pressure-lowering medications?
    Journal of clinical hypertension (Greenwich, Conn.), 2005, Volume: 7, Issue:6

    Topics: Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Diuretics; Drug Evaluation; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors; Treatment Outcome

2005
[When do combinations of diuretics make sense?].
    Therapeutische Umschau. Revue therapeutique, 2009, Volume: 66, Issue:11

    Topics: Chlorthalidone; Diuretics; Drug Therapy, Combination; Furosemide; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Kidney; Sodium Potassium Chloride Symporter Inhibitors; Time Factors

2009
Meta-analysis of dose-response characteristics of hydrochlorothiazide and chlorthalidone: effects on systolic blood pressure and potassium.
    American journal of hypertension, 2010, Volume: 23, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Hypertension; Potassium

2010
Chlorthalidone: the forgotten diuretic.
    Postgraduate medicine, 2012, Volume: 124, Issue:1

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2012
Chlorthalidone compared with hydrochlorothiazide in reducing cardiovascular events: systematic review and network meta-analyses.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Treatment Outcome

2012
Meta-analysis of dose-response relationships for hydrochlorothiazide, chlorthalidone, and bendroflumethiazide on blood pressure, serum potassium, and urate.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:6

    Topics: Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Potassium; Randomized Controlled Trials as Topic; Treatment Outcome; Uric Acid

2012
Thiazide and thiazide-like diuretics: an opportunity to reduce blood pressure in patients with advanced kidney disease.
    Current hypertension reports, 2012, Volume: 14, Issue:5

    Topics: Antihypertensive Agents; Chlorthalidone; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Renal Insufficiency, Chronic; Sodium Chloride Symporter Inhibitors; Sodium Potassium Chloride Symporter Inhibitors; Treatment Outcome

2012
Which diuretic is the preferred agent for treating essential hypertension: hydrochlorothiazide or chlorthalidone?
    Current cardiology reports, 2012, Volume: 14, Issue:6

    Topics: Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Practice Guidelines as Topic; Treatment Outcome

2012
Module 2: Rethinking the role of thiazide-type diuretics in the management of hypertension: which diuretic is best?
    The Journal of family practice, 2012, Volume: 61, Issue:8 Suppl

    Topics: Antihypertensive Agents; Chlorthalidone; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors

2012
Hydrochlorothiazide vs. chlorthalidone as the optimal diuretic for the management of hypertension.
    Current pharmaceutical design, 2013, Volume: 19, Issue:21

    Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Lipids; Practice Guidelines as Topic

2013
Is chlorthalidone better than hydrochlorothiazide in reducing cardiovascular events in hypertensives?
    Current opinion in cardiology, 2013, Volume: 28, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Randomized Controlled Trials as Topic

2013
Azilsartan medoxomil in the treatment of hypertension: the definitive angiotensin receptor blocker?
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:16

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Oxadiazoles

2013
Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension.
    The Cochrane database of systematic reviews, 2014, May-29, Issue:5

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Middle Aged; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors

2014
Clinical inquiry: How do hydrochlorothiazide and chlorthalidone compare for treating hypertension?
    The Journal of family practice, 2014, Volume: 63, Issue:4

    Topics: Antihypertensive Agents; Chlorthalidone; Evidence-Based Medicine; Humans; Hydrochlorothiazide; Hypertension

2014
Misconceptions and facts about treating hypertension.
    The American journal of medicine, 2015, Volume: 128, Issue:5

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Risk Factors; Sodium Chloride Symporter Inhibitors

2015
Head-to-head comparisons of hydrochlorothiazide with indapamide and chlorthalidone: antihypertensive and metabolic effects.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:5

    Topics: Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Indapamide; Potassium; Treatment Outcome

2015
Evidence-based diuretics: focus on chlorthalidone and indapamide.
    Future cardiology, 2015, Volume: 11, Issue:2

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Indapamide

2015
Diuretics for hypertension: Hydrochlorothiazide or chlorthalidone?
    Cleveland Clinic journal of medicine, 2015, Volume: 82, Issue:8

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2015
[All diuretics used in the treatment of hypertension are not the same].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2017, Volume: 45, Issue:1

    Topics: Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Indapamide

2017
Comparison of thiazide-like diuretics versus thiazide-type diuretics: a meta-analysis.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:11

    Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Chlorthalidone; Cholesterol; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Hyponatremia; Indapamide; Treatment Outcome; Water-Electrolyte Balance

2017
Hydrochlorothiazide and alternative diuretics versus renin-angiotensin system inhibitors for the regression of left ventricular hypertrophy: a head-to-head meta-analysis.
    Journal of hypertension, 2018, Volume: 36, Issue:6

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Diuretics, Potassium Sparing; Double-Blind Method; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Male; Middle Aged; Randomized Controlled Trials as Topic; Regression Analysis; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Treatment Outcome

2018
Hydrochlorothiazide vs chlorthalidone, indapamide, and potassium-sparing/hydrochlorothiazide diuretics for reducing left ventricular hypertrophy: A systematic review and meta-analysis.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:10

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics, Potassium Sparing; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Male; Middle Aged; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Thiazides

2018
Comparative efficacy and safety of chlorthalidone and hydrochlorothiazide-meta-analysis.
    Journal of human hypertension, 2019, Volume: 33, Issue:11

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome

2019
Combining angiotensin receptor blockers with chlorthalidone or hydrochlorothiazide - which is the better alternative? A meta-analysis.
    Systematic reviews, 2020, 08-24, Volume: 9, Issue:1

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Treatment Outcome

2020
Network meta-analysis of efficacy and safety of chlorthalidone and hydrochlorothiazide in hypertensive patients.
    Blood pressure monitoring, 2021, Apr-01, Volume: 26, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Network Meta-Analysis; Treatment Outcome

2021
Chlorthalidone versus hydrochlorothiazide: major cardiovascular events, blood pressure, left ventricular mass, and adverse effects.
    Journal of hypertension, 2021, 06-01, Volume: 39, Issue:6

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Observational Studies as Topic

2021
Superior antihypertensive and cardioprotective effects of chlorthalidone compared with hydrochlorothiazide.
    Drugs of today (Barcelona, Spain : 1998), 2021, Volume: 57, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2021
Thiazide and the Thiazide-Like Diuretics: Review of Hydrochlorothiazide, Chlorthalidone, and Indapamide.
    American journal of hypertension, 2022, 07-01, Volume: 35, Issue:7

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Thiazides

2022
[Which is better? Chlorthalidone or Hydrochlorothiazide].
    MMW Fortschritte der Medizin, 2023, Volume: 165, Issue:7

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2023
    MMW Fortschritte der Medizin, 2023, Volume: 165, Issue:9

    Topics: Chlorthalidone; Humans; Hydrochlorothiazide

2023

Trials

45 trial(s) available for hydrochlorothiazide and chlorthalidone

ArticleYear
Combination therapy with saluretics and atenolol in essential hypertension. Effects on blood pressure, electrolytes and uric acid.
    Acta medica Scandinavica. Supplementum, 1979, Volume: 625

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bendroflumethiazide; Chlorthalidone; Diuretics; Drug Evaluation; Drug Therapy, Combination; Electrolytes; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Mefruside; Middle Aged; Propanolamines; Uric Acid

1979
Double-blind comparison of hydrochlorothiazide plus triameterene therapy versus chlorthalidone therapy in hypertension.
    Southern medical journal, 1979, Volume: 72, Issue:7

    Topics: Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Placebos; Potassium; Time Factors; Triamterene

1979
A double-blind study of chlorthalidone and hydrochlorothiazide in an outpatient population of moderate hypertensives.
    Angiology, 1976, Volume: 27, Issue:12

    Topics: Adult; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Random Allocation; Uric Acid

1976
[An open comparative study of captopril + hydrochlorothiazide versus chlorthalidone for the treatment of mild and moderate primary hypertension].
    Arquivos brasileiros de cardiologia, 1992, Volume: 59, Issue:5

    Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Chi-Square Distribution; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1992
Diuretics, serum and intracellular electrolyte levels, and ventricular arrhythmias in hypertensive men.
    JAMA, 1992, Feb-26, Volume: 267, Issue:8

    Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Chlorthalidone; Double-Blind Method; Electrocardiography, Ambulatory; Electrolytes; Humans; Hydrochlorothiazide; Hypertension; Leukocytes, Mononuclear; Magnesium; Male; Middle Aged; Patient Compliance; Potassium; Triamterene

1992
[Effect of various diuretic doses on hemodynamics in patients with hypertension].
    Kardiologiia, 1988, Volume: 28, Issue:10

    Topics: Antihypertensive Agents; Chlorthalidone; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors

1988
Drug treatment trials in hypertension: a review.
    Preventive medicine, 1985, Volume: 14, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Random Allocation; Risk

1985
Prazosin once or twice daily?
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:1

    Topics: Adult; Aged; Amiloride; Atenolol; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Prazosin; Propranolol; Quinazolines

1985
Controlled-release potassium supplementation.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:7

    Topics: Adult; Blood Pressure; Chlorides; Chlorothiazide; Chlorthalidone; Clinical Trials as Topic; Delayed-Action Preparations; Drug Evaluation; Female; Furosemide; Gastrointestinal Diseases; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium Chloride; Potassium Deficiency

1974
Excretion of urinary casts after the administration of diuretics.
    British medical journal, 1972, Apr-22, Volume: 2, Issue:5807

    Topics: Chemical Precipitation; Chlorthalidone; Clinical Trials as Topic; Diuresis; Diuretics; Ethacrynic Acid; Fluorescent Antibody Technique; Furosemide; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kidney Diseases; Kidney Tubules; Male; Mucoproteins; Physical Exertion

1972
Haemodynamic changes in long-term therapy of essential hypertension: a comparative study of diuretics, alpha-methyldopa and clonidine.
    Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1

    Topics: Adult; Cardiac Output; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Polythiazide; Vascular Resistance

1973
Hemodynamic changes in long-term diuretic therapy of essential hypertension. A comparative study of chlorthalidone, polythiazide and hydrochlorothiazide.
    Acta medica Scandinavica, 1970, Volume: 187, Issue:6

    Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Chlorthalidone; Electrolytes; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxygen Consumption; Physical Exertion; Polythiazide; Posture; Rest

1970
Long-term effect of probenecid on diuretic-induced hyperuricemia.
    JAMA, 1966, Oct-10, Volume: 198, Issue:2

    Topics: Adult; Aged; Blood Chemical Analysis; Blood Pressure Determination; Body Weight; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Kidney Tubules; Male; Middle Aged; Potassium; Probenecid; Uric Acid

1966
Therapy of mild hypertension: an overview.
    The American journal of cardiology, 1984, Jan-27, Volume: 53, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Clinical Trials as Topic; Diet; Humans; Hydrochlorothiazide; Hypertension; Risk; Smoking; Vasodilator Agents

1984
The effects of two combinations of a beta-blocker and a diuretic on diuresis in normal subjects.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Mar-03, Volume: 65, Issue:9

    Topics: Adult; Atenolol; Chlorthalidone; Clinical Trials as Topic; Diuresis; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Male; Potassium; Sodium; Sotalol; Uric Acid; Urine

1984
Captopril and oxprenolol in a fixed combination with thiazide diuretics: comparison of their antihypertensive efficacy and metabolic effects.
    Clinical therapeutics, 1984, Volume: 6, Issue:5

    Topics: Adult; Blood Pressure; Captopril; Chlorthalidone; Cholesterol; Clinical Trials as Topic; Creatinine; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Proline; Random Allocation

1984
Biochemical changes in black and Indian hypertensive patients on diuretic therapy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1983, Dec-10, Volume: 64, Issue:25

    Topics: Adult; Amiloride; Blood Glucose; Blood Pressure; Chlorthalidone; Creatinine; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Male; Middle Aged; Potassium; Triamterene

1983
Serum cholesterol during treatment of hypertension with diuretic drugs.
    Archives of internal medicine, 1984, Volume: 144, Issue:4

    Topics: Chlorthalidone; Cholesterol; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Male; Random Allocation; Reserpine; Spironolactone; Triglycerides

1984
The antihypertensive and biochemical effects of hydrochlorothiazide/amiloride (Moduretic) versus chlorthalidone.
    The Journal of international medical research, 1980, Volume: 8, Issue:2

    Topics: Adult; Aged; Amiloride; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Pyrazines

1980
Effects of diuretics on plasma lipoproteins in healthy men.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:4

    Topics: Administration, Oral; Adult; Chlorthalidone; Cholesterol; Clinical Trials as Topic; Diuretics; Fatty Acids, Nonesterified; Furosemide; Humans; Hydrochlorothiazide; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phospholipids; Placebos; Sodium Chloride Symporter Inhibitors

1980
Urinary zinc excretion during treatment with different diuretics.
    Acta medica Scandinavica, 1980, Volume: 208, Issue:3

    Topics: Adult; Aged; Bendroflumethiazide; Bumetanide; Chlorthalidone; Clinical Trials as Topic; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Triamterene; Zinc

1980
Adverse reactions to pindolol administration.
    American heart journal, 1982, Volume: 104, Issue:2 Pt 2

    Topics: Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Pindolol; Propranolol; Random Allocation

1982
Moderate sodium restriction and various diuretics in the treatment of hypertension.
    Archives of internal medicine, 1981, Volume: 141, Issue:8

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diet, Sodium-Restricted; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium

1981
Effects of thiazide diuretics on plasma lipids and lipoproteins in mildly hypertensive patients: a double-blind controlled trial.
    Annals of internal medicine, 1981, Volume: 94, Issue:1

    Topics: Adult; Chlorthalidone; Cholesterol; Cholesterol, Dietary; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Random Allocation; Triglycerides

1981
Antihypertensive efficacy and tolerability of different drug regimens in isolated systolic hypertension in the elderly.
    European heart journal, 1994, Volume: 15, Issue:2

    Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Nifedipine; Patient Satisfaction; Treatment Outcome

1994
Glucose and insulin levels during diuretic therapy in hypertensive men.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 1

    Topics: Adult; Aged; Blood Glucose; Chlorthalidone; Diuretics; Electrolytes; Humans; Hydrochlorothiazide; Hypertension; Insulin; Intracellular Membranes; Male; Middle Aged; Multivariate Analysis; Obesity

1994
Comparison of different fixed antihypertensive combination drugs: a double-blind, placebo-controlled parallel group study.
    Journal of hypertension, 1997, Volume: 15, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Drug Tolerance; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Lisinopril; Male; Middle Aged; Safety; Verapamil

1997
Comparative antihypertensive effects of hydrochlorothiazide and chlorthalidone on ambulatory and office blood pressure.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:3

    Topics: Adult; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Office Visits; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Time Factors

2006
Antihypertensive efficacy of metoprolol XL/low dose chlorthalidone (6.25 mg) combination: a randomized, comparative study in indian patients with mild-to-moderate essential hypertension.
    European journal of medical research, 2009, Jul-22, Volume: 14, Issue:7

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Time Factors; Treatment Outcome

2009
Simultaneous determination of losartan and hydrochlorothiazide in human plasma by LC/MS/MS with electrospray ionization and its application to pharmacokinetics.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2009, Volume: 31, Issue:5

    Topics: Administration, Oral; Adult; Chlorthalidone; Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Humans; Hydrochlorothiazide; Losartan; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tetrazoles; Therapeutic Equivalency; Valine; Valsartan

2009
Long-term effects of chlorthalidone versus hydrochlorothiazide on electrocardiographic left ventricular hypertrophy in the multiple risk factor intervention trial.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Combined Modality Therapy; Diuretics; Electrocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Risk Factors; Treatment Outcome

2011
Azilsartan medoxomil plus chlorthalidone reduces blood pressure more effectively than olmesartan plus hydrochlorothiazide in stage 2 systolic hypertension.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:2

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Black People; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Severity of Illness Index; Tetrazoles; Treatment Outcome; White People

2012
Antihypertensive efficacy of hydrochlorothiazide vs chlorthalidone combined with azilsartan medoxomil.
    The American journal of medicine, 2012, Volume: 125, Issue:12

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Creatinine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxadiazoles; Potassium; Systole

2012
Comparison of the efficacy between hydrochlorothiazide and chlorthalidone on central aortic pressure when added on to candesartan in treatment-naïve patients of hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:1

    Topics: Adult; Antihypertensive Agents; Arterial Pressure; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Vascular Stiffness

2013
Safety and tolerability of azilsartan medoxomil in subjects with essential hypertension: a one-year, phase 3, open-label study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2016, Volume: 38, Issue:2

    Topics: Adult; Aged; Benzimidazoles; Chlorthalidone; Cohort Studies; Dizziness; Drug Therapy, Combination; Essential Hypertension; Fatigue; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxadiazoles; Sodium Chloride Symporter Inhibitors; Treatment Outcome

2016
Efficacy of Low-Dose Chlorthalidone and Hydrochlorothiazide as Assessed by 24-h Ambulatory Blood Pressure Monitoring.
    Journal of the American College of Cardiology, 2016, Feb-02, Volume: 67, Issue:4

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Retrospective Studies; Treatment Outcome

2016
Comparison of long-term safety of fixed-dose combinations azilsartan medoxomil/chlorthalidone vs olmesartan medoxomil/hydrochlorothiazide.
    Journal of clinical hypertension (Greenwich, Conn.), 2017, Volume: 19, Issue:9

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Olmesartan Medoxomil; Oxadiazoles; Treatment Outcome

2017
A randomized titrate-to-target study comparing fixed-dose combinations of azilsartan medoxomil and chlorthalidone with olmesartan and hydrochlorothiazide in stage-2 systolic hypertension.
    Journal of hypertension, 2018, Volume: 36, Issue:4

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Chlorthalidone; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles

2018
Long-term efficacy and tolerability of azilsartan medoxomil/chlorthalidone vs olmesartan medoxomil/hydrochlorothiazide in chronic kidney disease.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:4

    Topics: Aged; Benzimidazoles; Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Olmesartan Medoxomil; Oxadiazoles; Renal Insufficiency, Chronic; Treatment Outcome

2018
Comparison of Effectiveness of Azilsartan Medoxomil and Olmesartan in Blacks Versus Whites With Systemic Hypertension.
    The American journal of cardiology, 2018, 11-01, Volume: 122, Issue:9

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Black or African American; Chlorthalidone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles; United States; White People

2018
Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension: a protocol for a factorial randomized controlled trial.
    Trials, 2019, Dec-16, Volume: 20, Issue:1

    Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Brazil; Chlorthalidone; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Time Factors; Treatment Outcome

2019
Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.
    Advances in therapy, 2022, Volume: 39, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Artery Disease; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Metoprolol; Telmisartan; Tetrazoles

2022
Design of a pragmatic clinical trial embedded in the Electronic Health Record: The VA's Diuretic Comparison Project.
    Contemporary clinical trials, 2022, Volume: 116

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Electronic Health Records; Humans; Hydrochlorothiazide; Hypertension; Prospective Studies

2022
Comparative antiplatelet effects of chlorthalidone and hydrochlorothiazide.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:10

    Topics: Antihypertensive Agents; Aspirin; Blood Pressure; Chlorthalidone; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Prospective Studies

2022
Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events.
    The New England journal of medicine, 2022, 12-29, Volume: 387, Issue:26

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors

2022

Other Studies

157 other study(ies) available for hydrochlorothiazide and chlorthalidone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.
    Bioorganic & medicinal chemistry letters, 2008, Apr-15, Volume: 18, Issue:8

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Computer Simulation; Crystallography, X-Ray; Humans; Indapamide; Isoenzymes; Mice; Models, Molecular; Molecular Structure

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Idiopathic edema as a cause of nonarticular rheumatism.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:4

    Topics: Adult; Body Weight; Capillary Permeability; Chlorthalidone; Dextroamphetamine; Edema; Female; Humans; Hydrochlorothiazide; Middle Aged; Rheumatic Diseases; Sodium; Spironolactone; Water-Electrolyte Balance

1979
Diuretics and cholesterol elevation.
    JAMA, 1979, Oct-12, Volume: 242, Issue:15

    Topics: Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Polythiazide; Sodium Chloride Symporter Inhibitors

1979
[Serum and total body potassium during treatment with chlortalidone and hydrochlorothiazide. Influence of triamterene (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1977, Dec-16, Volume: 102, Issue:50

    Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Time Factors; Triamterene

1977
Ticrynafen, a uricosuric antihypertensive diuretic.
    Clinical pharmacology and therapeutics, 1978, Volume: 23, Issue:4

    Topics: Adult; Antihypertensive Agents; Chlorthalidone; Diuretics; Drug Interactions; Ethacrynic Acid; Furosemide; Glycolates; Humans; Hydrochlorothiazide; Male; Natriuresis; Phenoxyacetates; Thiophenes; Uricosuric Agents

1978
The site and mode of action of some sulfonamide-derived diuretics.
    The Medical clinics of North America, 1975, Volume: 59, Issue:3

    Topics: Acetazolamide; Aminohippuric Acids; Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Chlorides; Chlorothiazide; Chlorthalidone; Cyclopenthiazide; Depression, Chemical; Dichlorphenamide; Diffusion; Diuretics; Hydrochlorothiazide; Kidney Cortex; Kidney Medulla; Natriuresis; Probenecid; Rabbits; Sodium; Trichlormethiazide

1975
Abnormal electrocardiograms and cardiovascular risk: role of silent myocardial ischemia. Evidence from MRFIT.
    The American journal of cardiology, 1992, Nov-16, Volume: 70, Issue:16

    Topics: Adult; Antihypertensive Agents; Chlorthalidone; Cholesterol, Dietary; Coronary Disease; Electrocardiography; Humans; Hydralazine; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Missouri; Myocardial Ischemia; Reserpine; Risk Factors; Smoking; Smoking Cessation; Smoking Prevention

1992
Haemodynamic resistance of forearm vessels during prolonged drug treatment of essential hypertension.
    Cor et vasa, 1990, Volume: 32, Issue:1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Forearm; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Nifedipine; Propranolol; Vascular Resistance

1990
Unexpected effects of treating hypertension in men with electrocardiographic abnormalities: a critical analysis.
    Circulation, 1986, Volume: 73, Issue:1

    Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiomegaly; Catecholamines; Chlorthalidone; Coronary Disease; Death, Sudden; Diuretics; Electrocardiography; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Magnesium; Male; Middle Aged; Mortality; Myocardial Infarction; Potassium; Regression Analysis; Research; Risk

1986
[A beta blockader-diuretic combination in long-term anti-hypertensive therapy. Undesirable effects on blood potassium].
    Minerva cardioangiologica, 1985, Volume: 33, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Chlorthalidone; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged

1985
[Hemodynamic mechanisms of the hypotensive effect of hypothiazide and oxodolin].
    Klinicheskaia meditsina, 1987, Volume: 65, Issue:4

    Topics: Adult; Antihypertensive Agents; Chlorthalidone; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Middle Aged

1987
Relationship of diuretic therapy and serum magnesium levels among participants in the Multiple Risk Factor Intervention Trial.
    American journal of epidemiology, 1985, Volume: 122, Issue:6

    Topics: Adult; Blood Pressure; California; Chlorthalidone; Coronary Disease; Diet; Epidemiologic Methods; Humans; Hydrochlorothiazide; Hypertension; Magnesium; Magnesium Deficiency; Male; Middle Aged; Pennsylvania; Potassium; Risk; Spectrophotometry, Atomic; Water

1985
Thiazides: A cause of necrotising vasculitis?
    Lancet (London, England), 1965, Nov-13, Volume: 2, Issue:7420

    Topics: Adult; Aged; Chlorthalidone; Diuretics; Drug Hypersensitivity; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Skin Diseases; Vascular Diseases

1965
[Studies in the rat on the problem of the diabetogenic effect of saluretics].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1965, Sep-27, Volume: 251, Issue:5

    Topics: Acetazolamide; Animals; Benzothiadiazines; Blood Glucose; Chlorthalidone; Diazoxide; Glucose Tolerance Test; Hydrochlorothiazide; Hyperglycemia; Ouabain; Potassium Chloride; Rats

1965
[Therapy of the nephrotic syndrome].
    Deutsche medizinische Wochenschrift (1946), 1968, Mar-08, Volume: 93, Issue:10

    Topics: Adrenocorticotropic Hormone; Azathioprine; Chlorambucil; Chlorthalidone; Diet, Sodium-Restricted; Dietary Proteins; Diuretics; Furosemide; Glucocorticoids; Humans; Hydrochlorothiazide; Immunosuppressive Agents; Mercaptopurine; Methandrostenolone; Nephrotic Syndrome; Prednisolone; Prednisone

1968
[Angiotensin and saluretics in nephrogenic diabetes insipidus of early infancy].
    Zeitschrift fur Kinderheilkunde, 1967, Volume: 101, Issue:1

    Topics: Angiotensin II; Body Temperature; Chlorthalidone; Diabetes Insipidus; Electrolytes; Female; Furosemide; Humans; Hydrochlorothiazide; Hypernatremia; Infant, Newborn; Kidney; Kidney Tubules; Sodium; Spironolactone; Sweat

1967
[Effect of several saluretic agents on smooth muscle. A contribution to the varied effects of saluretic agents on glomerular filtration (author's transl)].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1974, Volume: 164, Issue:1

    Topics: Animals; Chlorthalidone; Diuretics; Female; Furans; Furosemide; Glomerular Filtration Rate; Hemodynamics; Hydrochlorothiazide; Inulin; Kidney; Kidney Function Tests; Male; Muscle Contraction; Norepinephrine; Papaverine; Rats; Receptors, Adrenergic; Vas Deferens

1974
Antihypertensive drugs and depression.
    Psychological medicine, 1974, Volume: 4, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Bethanidine; Chlorthalidone; Depression; Diuretics; Drug Therapy, Combination; Fatigue; Furosemide; Guanethidine; Humans; Hydrochlorothiazide; Methyldopa; Middle Aged; Phenobarbital; Potassium; Pyrazines; Reserpine; Self-Assessment; Sodium Chloride Symporter Inhibitors; Theobromine

1974
[Is essential hypertension still a disease entity? Definition of hyporeninemic hypertension].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Aldosterone; Amiloride; Chlorthalidone; Diagnosis, Differential; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Mineralocorticoids; Prognosis; Renin; Sodium Chloride; Spironolactone; Sympathetic Nervous System

1974
Clinical efficacy of fixed combinations of saluretic agents and potassium in sustained release form for the treatment of arterial hypertension.
    European journal of clinical pharmacology, 1972, Volume: 4, Issue:3

    Topics: Blood Pressure; Chlorides; Chlorthalidone; Creatinine; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Sodium

1972
[Antihypertensive agents].
    Die Pharmazie, 1972, Volume: 27, Issue:11

    Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlorisondamine; Chlorthalidone; Diuretics; Furosemide; Guanethidine; Guanidines; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Mecamylamine; Methyldopa; Pain; Parotid Gland; Pempidine; Phentolamine; Structure-Activity Relationship; Sulfonamides

1972
[Hyperuricemia due to diuretics].
    Minerva medica, 1973, Jan-20, Volume: 64, Issue:4

    Topics: Acetazolamide; Aged; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Gout; Humans; Hydrochlorothiazide; Middle Aged; Spironolactone; Sulfonamides; Triamterene; Uric Acid

1973
How to treat arterial hypertension.
    American family physician, 1973, Volume: 7, Issue:4

    Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Cooperative Behavior; Diazoxide; Diuretics; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Methyldopa; Physician-Patient Relations; Reserpine; Spironolactone; Sulfonamides; Triamterene

1973
[Therapy of EPH gestosis].
    Deutsche medizinische Wochenschrift (1946), 1973, Jul-06, Volume: 98, Issue:27

    Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Magnesium Sulfate; Mannitol; Phenobarbital; Phytotherapy; Plants, Medicinal; Pre-Eclampsia; Pregnancy; Proteinuria; Rauwolfia

1973
[Respective roles of hemodynamic or humoral factors and of hypotensive or salidiuretic drugs in the development of essential hypertension].
    Pathologie et biologie, 1965, Volume: 13, Issue:21

    Topics: Adult; Chlorthalidone; Diet, Sodium-Restricted; Electrocardiography; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Male; Methyldopa; Middle Aged; Prognosis; Reserpine; Sodium; Spironolactone; Sympathectomy

1965
Diuretic-induced hyponatremia.
    Annals of internal medicine, 1971, Volume: 75, Issue:6

    Topics: Adult; Aged; Alkalosis; Bendroflumethiazide; Biological Assay; Blood Urea Nitrogen; Bromine; Carbon Dioxide; Chlorides; Chlorpropamide; Chlorthalidone; Creatinine; Diagnosis, Differential; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hypokalemia; Hyponatremia; Hypopituitarism; Hypothyroidism; Male; Methyclothiazide; Middle Aged; Natriuresis; Osmolar Concentration; Polythiazide; Potassium Isotopes; Radioisotope Dilution Technique; Radioisotopes; Sodium Isotopes; Tritium; Vasopressins; Vomiting; Water-Electrolyte Balance

1971
Prolonged treatment with clonidine: comparative antihypertensive effects alone and with a diuretic agent.
    The American journal of cardiology, 1972, Volume: 30, Issue:5

    Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clonidine; District of Columbia; Diuretics; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1972
[Lactate and uric acid metabolism under the effect of saluretics].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1969, Volume: 75

    Topics: Chlorthalidone; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Lactates; Uric Acid

1969
[Some aspects of renal metabolism of citric acid].
    Minerva medica, 1970, Sep-01, Volume: 61, Issue:70

    Topics: Adult; Age Factors; Aged; Chlorthalidone; Citrates; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Kidney; Kidney Diseases; Middle Aged

1970
Renal effects and side effects of diuretics.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:1

    Topics: Absorption; Acetazolamide; Acidosis; Animals; Antihypertensive Agents; Bicarbonates; Chlorides; Chlorthalidone; Diuretics; Furosemide; Hydrochlorothiazide; Hypokalemia; Inulin; Kidney Concentrating Ability; Kidney Tubules; Punctures; Rats; Sodium; Time Factors

1970
[Serum zinc level and carbonic anhydrase inhibition].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Feb-15, Volume: 22, Issue:4

    Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chlorthalidone; Humans; Hydrochlorothiazide; Indicators and Reagents; Zinc

1967
[Quantitative scintigraphy with insulin I-131. Effect of saluretics on the distribution of bovine insulin I-131 in rabbits].
    Acta isotopica, 1968, Sep-30, Volume: 8, Issue:1

    Topics: Animals; Chlorthalidone; Diuretics; Furosemide; Hydrochlorothiazide; Insulin; Iodine Isotopes; Kidney; Liver; Rabbits; Radionuclide Imaging

1968
[Objectives and methods in therapy of essential arterial hypertension].
    Cardiologia pratica, 1968, Volume: 19, Issue:4

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Potassium; Reserpine; Triamterene

1968
[Influence of diuretics on the survival of 180 patients with cirrhosis of the liver and ascites].
    Schweizerische medizinische Wochenschrift, 1969, Feb-08, Volume: 99, Issue:6

    Topics: Adult; Aged; Alcoholism; Ascites; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Humans; Hydrochlorothiazide; Liver Cirrhosis; Middle Aged; Spironolactone; Triamterene

1969
[Studies on uric acid metabolism disorders following administration of saluretics].
    Deutsche medizinische Wochenschrift (1946), 1965, Oct-22, Volume: 90, Issue:43

    Topics: Chlorothiazide; Chlorthalidone; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Hydroflumethiazide; Hypertension; Natriuresis; Uric Acid

1965
Effect of hydrochlorothiazide and chlorthalidon on renal reabsorption of glucose.
    Scandinavian journal of clinical and laboratory investigation, 1965, Volume: 17, Issue:4

    Topics: Adult; Aged; Chlorthalidone; Glucose; Humans; Hydrochlorothiazide; Kidney; Kidney Function Tests; Middle Aged

1965
[Codification and practical importance of saliuretic test in polyuropolydipsic syndromes].
    Semaine therapeutique, 1963, Volume: 39, Issue:5

    Topics: Chlorthalidone; Diabetes Insipidus; Humans; Hydrochlorothiazide; Polyuria

1963
Analysis of urea excretion with special reference to the influence of abrupt change in urine flow.
    Japanese circulation journal, 1965, Volume: 29, Issue:10

    Topics: Adult; Animals; Chlorides; Chlorthalidone; Diabetes Insipidus; Diuresis; Female; Humans; Hydrochlorothiazide; Kidney; Kidney Diseases; Male; Mannitol; Middle Aged; Rabbits; Sodium; Urea; Urine; Vasopressins

1965
A comparative clinical study of hydrochlorothiazide and chlorthalidone in oedema states.
    The Indian practitioner, 1966, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Chlorthalidone; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1966
Effects of diuretic agents on serum and tissue electrolytes in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 122, Issue:1

    Topics: Animals; Blood; Chlorthalidone; Diuretics; Hydrochlorothiazide; Hypokalemia; Polythiazide; Potassium; Rats; Sodium; Water-Electrolyte Balance

1966
Effect of two diuretic drugs on liquid consumption and free choice of alcohol in albino rats.
    Nature, 1967, Jan-21, Volume: 213, Issue:5073

    Topics: Animals; Behavior, Animal; Chlorthalidone; Drinking; Ethanol; Hydrochlorothiazide; Male; Rats

1967
Acute diuretic induced hyperglycaemia in rats.
    Life sciences, 1967, May-01, Volume: 6, Issue:9

    Topics: Acetazolamide; Adrenalectomy; Animals; Bendroflumethiazide; Chlorthalidone; Ergotamine; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Hyperglycemia; Male; Organomercury Compounds; Rats; Reserpine; Spironolactone

1967
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
    Minerva medica, 1967, Nov-07, Volume: 58, Issue:89

    Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Female; Furosemide; Gout; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Liver Cirrhosis; Male; Middle Aged; Organomercury Compounds; Spironolactone; Sulfonamides; Triamterene; Uric Acid

1967
Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias.
    The American journal of cardiology, 1983, Nov-01, Volume: 52, Issue:8

    Topics: Adult; Aged; Ambulatory Care; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Chlorthalidone; Diuretics; Electrocardiography; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Middle Aged; Monitoring, Physiologic; Potassium; Potassium Chloride; Triamterene

1983
[Mechanism of action of benzothiadiazides in arterial hypertension: the energetic theory].
    Annales de medecine interne, 1982, Volume: 133, Issue:8

    Topics: Adenylyl Cyclase Inhibitors; Animals; Chlorthalidone; Columbidae; Cyclic AMP; Diuretics; Energy Metabolism; Erythrocyte Membrane; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Ticrynafen

1982
Diuretic regimens in essential hypertension. A comparison of hypokalemic effects, BP control, and cost.
    Archives of internal medicine, 1983, Volume: 143, Issue:9

    Topics: Blood Pressure; Chlorthalidone; Cost-Benefit Analysis; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Triamterene

1983
Hemodynamic actions of diuretic agents.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:2

    Topics: Animals; Blood Pressure; Chlorthalidone; Diuretics; Furosemide; Heart Rate; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Rats; Stroke Volume; Time Factors

1983
Some wrong-way chemical changes during antihypertensive treatment: comparison of indapamide and related agents.
    American heart journal, 1983, Volume: 106, Issue:1 Pt 2

    Topics: Adult; Antihypertensive Agents; Chemical Phenomena; Chemistry; Chlorthalidone; Diuretics; Humans; Hydralazine; Hydrochlorothiazide; Hypercholesterolemia; Hyperglycemia; Hypokalemia; Indapamide; Middle Aged; Myocardial Infarction; Uric Acid

1983
Diuretic induced hypokalemia in the elderly.
    The Journal of family practice, 1982, Volume: 14, Issue:4

    Topics: Aged; Chlorthalidone; Diet; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hypokalemia; Male; Middle Aged; Potassium; Retrospective Studies; Risk; Triamterene

1982
[Effect of antihypertensive therapy on oxygen consumption of the myocardium. I. Hydrochlorothiazide and chlorthalidone].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:12

    Topics: Adult; Chlorthalidone; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Myocardium; Oxygen Consumption

1981
[Comparative study of the association of propranolol-chlorthalidone and the fixed combination of timolol-hydrochlorothiazide-amiloride in the treatment of arterial hypertension].
    Arquivos brasileiros de cardiologia, 1981, Volume: 36, Issue:1

    Topics: Amiloride; Antihypertensive Agents; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Propranolol; Timolol

1981
A comparison of chlorthalidone-reserpine and hydrochlorothiazide-methyldopa as step 2 therapy for hypertension.
    Clinical therapeutics, 1981, Volume: 4, Issue:3

    Topics: Chlorthalidone; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Reserpine

1981
Compared effects of indapamide, hydrochlorothiazide and chlorthalidone on electrical and mechanical activities in vascular smooth muscle.
    European journal of pharmacology, 1981, Oct-22, Volume: 75, Issue:2-3

    Topics: Animals; Calcium; Chlorthalidone; Diuretics; Hydrochlorothiazide; In Vitro Techniques; Indapamide; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Rats

1981
[Treatment of arterial hypertension: comparative study of atenolol + chlorthalidone vs. timolol maleate-hydrochlorthiazide-amiloride association].
    Arquivos brasileiros de cardiologia, 1981, Volume: 37, Issue:6

    Topics: Adult; Aged; Amiloride; Atenolol; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Pyrazines; Timolol

1981
[Diagnosis and therapy of diabetes insipidus].
    Tierarztliche Praxis, 1980, Volume: 8, Issue:2

    Topics: Adult; Carbamazepine; Chlorpropamide; Chlorthalidone; Deamino Arginine Vasopressin; Diabetes Insipidus; Humans; Hydrochlorothiazide; Pituitary Function Tests; Vasopressins

1980
Hypokalaemia and diuretics: an analysis of publications.
    British medical journal, 1980, Mar-29, Volume: 280, Issue:6218

    Topics: Chlorothiazide; Chlorthalidone; Coronary Disease; Diuretics; Dose-Response Relationship, Drug; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Potassium; Sodium Chloride Symporter Inhibitors; Time Factors

1980
Urapidil compared with diuretics in the treatment of mild-to-moderate essential hypertensive patients: effects on glucose metabolism, insulin sensitivity, and lipid profile.
    Blood pressure. Supplement, 1994, Volume: 4

    Topics: Adult; Antihypertensive Agents; Chlorthalidone; Female; Glucose; Humans; Hydrochlorothiazide; Hypertension; Insulin; Lipids; Male; Middle Aged; Piperazines

1994
Cost-benefit of medicines--indapamide compared with other thiazide diuretics.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1994, Volume: 84, Issue:9

    Topics: Chlorthalidone; Cost-Benefit Analysis; Humans; Hydrochlorothiazide; Indapamide

1994
Combination products as first-line pharmacotherapy.
    Archives of internal medicine, 1994, Jul-11, Volume: 154, Issue:13

    Topics: Betaxolol; Bisoprolol; Chlorthalidone; Drug Approval; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; United States

1994
Do thiazides reduce intestinal oxalate absorption?: a study in vitro using rabbit colon.
    Clinical science (London, England : 1979), 1994, Volume: 86, Issue:3

    Topics: Animals; Bendroflumethiazide; Chlorthalidone; Colon; Culture Techniques; Diuretics; Hydrochlorothiazide; Hydroflumethiazide; Intestinal Absorption; Oxalates; Rabbits; Sodium Chloride Symporter Inhibitors; Trichlormethiazide

1994
Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective dose.
    Journal of the American Geriatrics Society, 1999, Volume: 47, Issue:8

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Confidence Intervals; Databases as Topic; Diuretics; Drug Compounding; Evaluation Studies as Topic; Female; Humans; Hydrochlorothiazide; Logistic Models; Male; Metolazone; Metoprolol; Myocardial Infarction; Odds Ratio; Ontario; Propranolol; Retrospective Studies; Sex Factors; Sodium Chloride Symporter Inhibitors; Timolol

1999
Angiotensin-converting-enzyme inhibitors and diuretics for hypertension.
    The New England journal of medicine, 2003, Jul-03, Volume: 349, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chlorthalidone; Coronary Disease; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2003
[Hyperglycemic effect by means of salidiuretics in diabetes mellitus].
    Helvetica medica acta, 1962, Volume: 29

    Topics: Chlorthalidone; Diabetes Mellitus; Humans; Hydrochlorothiazide; Hyperglycemia

1962
[Effect of 1-oxo-3-(3'-sulfamoyl-4'-chlorophenyl)-3-hydroxyisoindolinum on urinary electrolyte excretion in comparison with some other diuretics].
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Chlorthalidone; Diuretics; Electrolytes; Humans; Hydrochlorothiazide

1963
[The influence of sulfonamide diuretics on blood sugar regulation].
    La Clinica terapeutica, 1962, Dec-31, Volume: 23

    Topics: Blood Glucose; Chlorothiazide; Chlorthalidone; Diabetes Mellitus; Diuretics; Hydrochlorothiazide; Sulfanilamide; Sulfanilamides; Sulfonamides

1962
Reversal of thiazide-induced transient hyperuricemia by uricosuric agents.
    The New England journal of medicine, 1962, Dec-13, Volume: 267

    Topics: Chlorthalidone; Humans; Hydrochlorothiazide; Hyperuricemia; Probenecid; Pyrazoles; Thiazides; Uric Acid; Uricosuric Agents

1962
[Clinical contribution to the diabetogenic effect of saluretics].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1962, Volume: 43

    Topics: Chlorothiazide; Chlorthalidone; Diabetes Mellitus; Diuretics; Humans; Hydrochlorothiazide

1962
[On the medical prevention or inhibition of lacation].
    Zentralblatt fur Gynakologie, 1963, Feb-09, Volume: 85

    Topics: Breast Feeding; Chlorthalidone; Diuretics; Female; Humans; Hydrochlorothiazide; Lactation

1963
TREATMENT OF EDEMA BY THE COMBINED ADMINISTRATION OF CHEMICALLY DIFFERENT DIURETIC AGENTS.
    The American journal of cardiology, 1963, Volume: 12

    Topics: Ascites; Chlorthalidone; Diuretics; Edema; Heart Failure; Humans; Hydrochlorothiazide; Organomercury Compounds; Trichlormethiazide

1963
[DIURETIC THERAPY OF DECOMPENSATED HEPATIC CIRRHOSIS].
    Minerva medica, 1963, Sep-22, Volume: 54

    Topics: Blood Chemical Analysis; Chlorothiazide; Chlorthalidone; Diuresis; Diuretics; Electrolytes; Humans; Hydrochlorothiazide; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Prednisone; Progesterone; Spironolactone; Urine

1963
[RENAL CARBONIC ANHYDRASE: ITS PHYSIOLOGICAL ACTION; ITS INHIBITORS].
    La Revue du praticien, 1963, Dec-01, Volume: 13

    Topics: Acetazolamide; Acidosis; Ammonia; Carbonic Anhydrases; Chlorothiazide; Chlorthalidone; Dichlorphenamide; Diuretics; Edema; Enzyme Inhibitors; Hydrochlorothiazide; Hypokalemia; Kidney; Physiology; Pulmonary Heart Disease; Respiratory Insufficiency

1963
[ON ION TRANSPORT BEFORE AND AFTER TREATMENT OF CONGESTIVE HEART FAILURE].
    Turk Tip Cemiyeti mecmuasi, 1963, Volume: 29

    Topics: Chlorthalidone; Coronary Disease; Digitalis Glycosides; Diuretics; Electrolytes; Heart Failure; Humans; Hydrochlorothiazide; Ion Transport; Kidney Function Tests; Metabolism; Mitral Valve Insufficiency; Mitral Valve Stenosis; Organomercury Compounds; Pulmonary Heart Disease

1963
[A COMPARATIVE STUDY ON SULFONAMIDE DIURETICS].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1963, Volume: 54

    Topics: Acetazolamide; Acidosis; Alkalosis; Blood Pressure; Cats; Chlorothiazide; Chlorthalidone; Diuretics; Drug Tolerance; Heart; Hydrochlorothiazide; Ileum; Kidney Function Tests; Pharmacology; Phenolphthaleins; Physiology; Rabbits; Research; Respiratory Function Tests; Sulfonamides; Toxicology; Urine

1963
PROPHYLACTIC USE OF CHLORTHALIDONE IN PREGNANCY.
    Obstetrics and gynecology, 1964, Volume: 23

    Topics: Blood Pressure; Chlorthalidone; Eclampsia; Edema; Female; Humans; Hydrochlorothiazide; Infant, Newborn; Pre-Eclampsia; Pregnancy; Proteinuria; Sodium; Toxicology; Urine

1964
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
    Vie medicale (Paris, France : 1920), 1964, Volume: 45

    Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics; Edema; Heart Failure; Hepatic Encephalopathy; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypokalemia; Hyponatremia; Kidney Diseases; Liver Cirrhosis; Spironolactone; Sulfonamides; Toxicology; Triamterene

1964
[ON THE EFFECT OF SALI-DIURETICS IN DIABETES INSIPIDUS].
    Deutsches Archiv fur klinische Medizin, 1964, Jan-09, Volume: 209

    Topics: Acetazolamide; Adolescent; Chlorthalidone; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Diuretics; Hydrochlorothiazide; Kidney Function Tests; Pharmacology; Spironolactone; Vasopressins; Water-Electrolyte Balance

1964
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
    Nordisk medicin, 1964, Apr-23, Volume: 71

    Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine; Hemiplegia; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Methyldopa; Neurologic Manifestations; Reserpine; Toxicology

1964
CARDIAC AND METABOLIC DISEASE, AND INFECTIONS IN THE OBSTETRIC PATIENT.
    Clinical obstetrics and gynecology, 1964, Volume: 13

    Topics: Acetazolamide; Acid-Base Equilibrium; Blood Circulation; Chlorothiazide; Chlorthalidone; Diet, Sodium-Restricted; Diuretics; Female; Heart Failure; Humans; Hydrochlorothiazide; Hyperemesis Gravidarum; Infusions, Parenteral; Insulin; Kidney Tubules; Metabolic Diseases; Metabolism; Organomercury Compounds; Pathology; Potassium; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Infectious; Pregnancy in Diabetics; Sodium; Water-Electrolyte Balance

1964
[URIC ACID METABOLISM AND SALIDIURETICS].
    Deutsche medizinische Wochenschrift (1946), 1964, Jun-05, Volume: 89

    Topics: Aged; Chlorothiazide; Chlorthalidone; Diagnosis; Gout; Humans; Hydrochlorothiazide; Metabolism; Toxicology; Uric Acid; Uricosuric Agents

1964
THE EFFECT OF SALURETICS ON PULSE RATE, BLOOD PRESSURE AND ELECTROCARDIOGRAM DURING EXERCISE IN NORMAL SUBJECTS.
    Acta medica Scandinavica, 1964, Volume: 175

    Topics: Aspirin; Biomedical Research; Blood; Blood Pressure; Blood Pressure Determination; Chlorides; Chlorthalidone; Diuretics; Edema; Electrocardiography; Exercise Test; Extracellular Space; Heart Rate; Hematocrit; Hemoglobins; Hydrochlorothiazide; Hypertension; Hypokalemia; Pharmacology; Physical Exertion; Potassium; Pulse; Sodium; Toxicology; Water-Electrolyte Balance

1964
[THE INTRODUCTION OF ALDOSTERONE ANTAGONISTS IN THERAPY].
    Les Cahiers du College de medecine des hopitaux de Paris, 1964, Volume: 5

    Topics: Chlorthalidone; Edema; Humans; Hydrochlorothiazide; Hydroflumethiazide; Mineralocorticoid Receptor Antagonists; Spironolactone

1964
A NEW EFFECTIVE DIURETIC--LASIX.
    British medical journal, 1964, Oct-10, Volume: 2, Issue:5414

    Topics: Chlorthalidone; Diuretics; Drug Therapy; Furosemide; Heart Failure; Hydrochlorothiazide; Hypokalemia; Injections, Intravenous; Liver Cirrhosis; Potassium; Pulmonary Edema; Sodium; Sodium, Dietary; Spironolactone; Toxicology; Urine

1964
[CLINICAL TRIAL OF A HYPOTENSIVE DRUG: 3,4-DIHYDROXY-D-L-PHENYLALANINE OR METHYLDOPA].
    La Presse medicale, 1964, Oct-17, Volume: 72

    Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Eye Manifestations; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypotension; Hypotension, Orthostatic; Methyldopa; Phenylalanine; Toxicology

1964
A CLINICAL TRIAL OF FRUSEMIDE.
    Lancet (London, England), 1964, Nov-21, Volume: 2, Issue:7369

    Topics: Biomedical Research; Blood Chemical Analysis; Chlorides; Chlorthalidone; Diuretics; Fluids and Secretions; Furosemide; Heart Failure; Hydrochlorothiazide; Organomercury Compounds; Pharmacology; Potassium; Sodium; Sodium, Dietary; Triamterene; Urine

1964
[CLINICAL EXPERIENCE OF 2,4,7-TRIAMINO-6-PHENYLPTERIDINE THERAPY UPON LONG TERM AND COMPOUND ADMINISTRATION WITH OTHER AGENTS].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, Jul-10, Volume: 53

    Topics: Adolescent; Biomedical Research; Chlorthalidone; Diuretics; Drug Therapy; Edema; Geriatrics; Hydrochlorothiazide; Hypertension; Nephrosis; Toxicology; Triamterene; Trichlormethiazide

1964
CORRECTION OF DIURETIC-INDUCED HYPOKALEMIA AND HYPERURICEMIA.
    The American journal of the medical sciences, 1965, Volume: 249

    Topics: Bicarbonates; Blood Chemical Analysis; Chlorthalidone; Diuretics; Drug Therapy; Geriatrics; Hydrochlorothiazide; Hyperuricemia; Hypokalemia; Potassium; Sulfinpyrazone; Toxicology; Triamterene; Uric Acid

1965
FUROSEMIDE (LASIX) AS A DIURETIC.
    Acta medica Scandinavica, 1965, Volume: 177

    Topics: Chlorothiazide; Chlorthalidone; Diuretics; Drug Therapy; Furosemide; Heart Failure; Hydrochlorothiazide; Liver Cirrhosis; Pulmonary Edema

1965
[Can hydrochlorothiazide and chlorthalidone be compared in the treatment of hypertension?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2004, Mar-18, Volume: 124, Issue:6

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors

2004
Thiazide-like diuretics attenuate agonist-induced vasoconstriction by calcium desensitization linked to Rho kinase.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:2

    Topics: Acute-Phase Proteins; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium; Chlorthalidone; Diuretics; DNA; Drug Resistance; Hydrochlorothiazide; In Vitro Techniques; Intracellular Membranes; Intracellular Signaling Peptides and Proteins; Male; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; rho-Associated Kinases; Sodium Chloride Symporter Inhibitors; Vasoconstriction; Vasoconstrictor Agents

2005
Experts argue not all diuretics the same.
    JAMA, 2007, Jul-04, Volume: 298, Issue:1

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Drug Utilization; Humans; Hydrochlorothiazide; Practice Patterns, Physicians'

2007
Which diuretic should be used for the treatment of hypertension?
    American family physician, 2008, Aug-15, Volume: 78, Issue:4

    Topics: Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors

2008
All thiazide-like diuretics are not chlorthalidone: putting the ACCOMPLISH study into perspective.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

2009
Using diuretics in practice--one opinion.
    Journal of clinical hypertension (Greenwich, Conn.), 2008, Volume: 10, Issue:11

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Practice Patterns, Physicians'

2008
Benazepril plus amlodipine or hydrochlorothiazide for hypertension.
    The New England journal of medicine, 2009, Mar-12, Volume: 360, Issue:11

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia

2009
The choice of thiazide diuretics: why chlorthalidone may replace hydrochlorothiazide.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:5

    Topics: Aged; Chlorthalidone; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States

2009
Choice of diuretic therapy and reconsideration for aldosterone receptors blockers.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Aldosterone; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Hypertension; Treatment Outcome

2010
[Chlorthalidone better than hydrochlorothiazide in hypertension].
    Nederlands tijdschrift voor geneeskunde, 2010, Volume: 154

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Treatment Outcome

2010
Thiazides diuretics in the treatment of nephrolithiasis: are we using them in an evidence-based fashion?
    International urology and nephrology, 2011, Volume: 43, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Chi-Square Distribution; Chlorthalidone; Dose-Response Relationship, Drug; Evidence-Based Medicine; Female; Humans; Hydrochlorothiazide; Indapamide; Kidney Calculi; Male; Middle Aged; Practice Patterns, Physicians'; Sodium Chloride Symporter Inhibitors

2011
Chlorthalidone versus hydrochlorothiazide as the preferred diuretic: is there a verdict yet?
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2011
Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4

    Topics: Adult; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cholesterol; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Myocardial Infarction; Potassium; Regression Analysis; Retrospective Studies; Risk Factors; Stroke; Uric Acid

2011
Managing erectile dysfunction in hypertensive patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:6

    Topics: Amides; Antihypertensive Agents; Benzopyrans; Chlorthalidone; Ethanolamines; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Impotence, Vasculogenic; Losartan; Male; Middle Aged; Nebivolol; Risk Factors

2011
Chlorthalidone versus hydrochlorothiazide: a tale of tortoises and a hare.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:6

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Electrocardiography; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male

2011
Guidelines for use of diuretics: a view from a member of JNC 7.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:5

    Topics: Chlorthalidone; Consensus Development Conferences as Topic; Diuretics; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Hypertension; Practice Guidelines as Topic; Sodium; Treatment Outcome; United States

2012
Thiazide and thiazide-like diuretics: perspectives on individualization of drug and dose based on therapeutic index.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:6

    Topics: Bendroflumethiazide; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Potassium; Uric Acid

2012
Potency of office blood pressure from hydrochlorothiazide and chlorthalidone fails to explain cardiovascular events.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Bendroflumethiazide; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Potassium; Uric Acid

2012
Best thiazide diuretic for hypertension.
    Canadian family physician Medecin de famille canadien, 2012, Volume: 58, Issue:6

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2012
The comparative effectiveness of hydrochlorothiazide and chlorthalidone in an observational cohort of veterans.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:9

    Topics: Aged; Blood Pressure; Chlorthalidone; Cohort Studies; Comparative Effectiveness Research; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Veterans

2012
Obesity and hypertension: It's about more than the numbers.
    Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:4

    Topics: Antihypertensive Agents; Chlorthalidone; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Evidence-Based Practice; Humans; Hydrochlorothiazide; Hypertension; Life Style; Metabolic Syndrome; Obesity; Randomized Controlled Trials as Topic; Risk Factors

2013
Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study.
    Annals of internal medicine, 2013, Mar-19, Volume: 158, Issue:6

    Topics: Aged; Antihypertensive Agents; Chlorthalidone; Follow-Up Studies; Hospitalization; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Hyponatremia; Male; Propensity Score; Retrospective Studies; Treatment Outcome

2013
Hydrochlorothiazide compared to chlorthalidone in reduction of urinary calcium in patients with kidney stones.
    Urolithiasis, 2013, Volume: 41, Issue:4

    Topics: Calcium; Chlorthalidone; Diuretics; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Recurrence; Retrospective Studies

2013
Determining the relative antihypertensive potency and relative cardiovascular risk reduction associated with different thiazide and thiazide-type diuretics.
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:6

    Topics: Bendroflumethiazide; Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Potassium; Uric Acid

2013
Chlorthalidone versus hydrochlorothiazide.
    Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Male

2013
Chlorthalidone versus hydrochlorothiazide.
    Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Male

2013
Chlorthalidone versus hydrochlorothiazide.
    Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Male

2013
Chlorthalidone versus hydrochlorothiazide.
    Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Male

2013
Chlorthalidone versus hydrochlorothiazide.
    Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Male

2013
Chlorthalidone versus hydrochlorothiazide.
    Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Male

2013
Evaluation of the efficacy and safety of a hydrochlorothiazide to chlorthalidone medication change in veterans with hypertension.
    Clinical therapeutics, 2013, Volume: 35, Issue:9

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Calcium; Chlorthalidone; Creatinine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Retrospective Studies; Treatment Outcome; United States; Veterans

2013
Phase quantification of antihypertensive drugs - Chlorthalidone, Hydrochlorothiazide, Losartan and combinations, Losartan/Chlorthalidone and Losartan/Hydrochlorothiazide - by the Rietveld method.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 88

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chemistry, Pharmaceutical; Chlorthalidone; Crystallization; Diuretics; Drug Stability; Hydrochlorothiazide; Losartan; Powders; Temperature; Time Factors; X-Ray Diffraction

2014
Chlorthalidone versus hydrochlorothiazide in hypertension treatment: do we have the evidence to decide?
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Male

2014
Risk of hyponatremia with diuretics: chlorthalidone versus hydrochlorothiazide.
    The American journal of medicine, 2014, Volume: 127, Issue:8

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Chlorthalidone; Diuretics; Female; Humans; Hydrochlorothiazide; Hyponatremia; Male; Middle Aged; Odds Ratio; Risk Factors; Young Adult

2014
Comparison of new-onset gout in adults prescribed chlorthalidone vs. hydrochlorothiazide for hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:12

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cohort Studies; Diuretics; Female; Gout; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Retrospective Studies

2014
Comparing clinical effectiveness and drug toxicity with hydrochlorothiazide and chlorthalidone using two potency ratios in a managed care population.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Electronic Health Records; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Managed Care Programs; Middle Aged; Retrospective Studies; Systole; Treatment Outcome; United States

2015
Cyclodextrin Micellar LC for Direct Selective Analysis of Combined Dosage Drugs in Urine.
    Journal of chromatographic science, 2015, Volume: 53, Issue:7

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adult; Antihypertensive Agents; Atenolol; beta-Cyclodextrins; Bisoprolol; Chlorthalidone; Chromatography, Liquid; Drug Combinations; Humans; Hydrochlorothiazide; Limit of Detection; Male; Micelles; Sodium Dodecyl Sulfate

2015
Indapamide: is it the better diuretic for hypertension?
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:5

    Topics: Blood Pressure; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Potassium

2015
Chlorthalidone vs. Hydrochlorothiazide for Treatment of Hypertension.
    American family physician, 2015, Dec-01, Volume: 92, Issue:11

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Chlorthalidone; Evidence-Based Practice; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Medication Therapy Management; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; United Kingdom

2015
Hydrochlorothiazide as the Diuretic of Choice for Hypertension: Time to Kick the Habit.
    Journal of the American College of Cardiology, 2016, Feb-02, Volume: 67, Issue:4

    Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chlorthalidone; Female; Humans; Hydrochlorothiazide; Hypertension; Male

2016
Efficacy of Low-Dose Chlorthalidone Versus Hydrochlorothiazide Remains Ambiguous.
    Journal of the American College of Cardiology, 2016, 07-26, Volume: 68, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2016
Reply: Efficacy of Low-Dose Chlorthalidone Versus Hydrochlorothiazide Remains Ambiguous.
    Journal of the American College of Cardiology, 2016, 07-26, Volume: 68, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2016
Chlorthalidone Versus Hydrochlorothiazide: A New Kind of Veterans Affairs Cooperative Study.
    Annals of internal medicine, 2016, 11-01, Volume: 165, Issue:9

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Research Design; United States; Veterans

2016
Trends in Antihypertensive Medication Use Among US Patients With Resistant Hypertension, 2008 to 2014.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:6

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Chlorthalidone; Cohort Studies; Drug Resistance; Drug Therapy, Combination; Drug Utilization; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Safety; Retrospective Studies; Risk Assessment; Severity of Illness Index; Spironolactone; Treatment Outcome; United States

2016
Long-term safety of different antihypertensive regimens: The risk of unfair comparisons.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:1

    Topics: Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Olmesartan Medoxomil; Oxadiazoles

2018
Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.
    Scientific reports, 2017, 11-22, Volume: 7, Issue:1

    Topics: Alleles; Biomarkers; Blood Pressure; CCAAT-Enhancer-Binding Protein-delta; Chlorthalidone; Diuretics; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrochlorothiazide; Logistic Models; Male; Middle Aged; Potassium; Reproducibility of Results; RNA, Messenger; ROC Curve; Transcription Factors; Uric Acid

2017
Treatment of hypertension in CKD patients with azilsartan/chlorthalidone vs olmesartan/hydrochlorothiazide.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:4

    Topics: Antihypertensive Agents; Benzimidazoles; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Oxadiazoles; Renal Insufficiency, Chronic; Tetrazoles

2018
Diuretics and left ventricular hypertrophy regression: The relationship that we commonly forget.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:10

    Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Potassium

2018
Which thiazide to choose-A "dynamic" question with a mundane answer?
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:12

    Topics: Blood Pressure Monitoring, Ambulatory; Carbonic Anhydrases; Chlorthalidone; Diuretics; Endothelium; Guidelines as Topic; Humans; Hydrochlorothiazide; Hypertension; Platelet Aggregation; Retrospective Studies; Sodium Chloride Symporter Inhibitors; Thiazides

2018
Interventricular vessel of the heart and diuretics.
    Journal of clinical hypertension (Greenwich, Conn.), 2019, Volume: 21, Issue:1

    Topics: Chlorthalidone; Diuretics; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Potassium

2019
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
    Journal of separation science, 2020, Volume: 43, Issue:8

    Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan

2020
Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension.
    JAMA internal medicine, 2020, 04-01, Volume: 180, Issue:4

    Topics: Antihypertensive Agents; Chlorthalidone; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Retrospective Studies

2020
Chlorthalidone and Hydrochlorothiazide for Treatment of Patients With Hypertension.
    JAMA internal medicine, 2020, 08-01, Volume: 180, Issue:8

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2020
Chlorthalidone and Hydrochlorothiazide for Treatment of Patients With Hypertension-Reply.
    JAMA internal medicine, 2020, 08-01, Volume: 180, Issue:8

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2020
Chlorthalidone and Hydrochlorothiazide for Treatment of Patients With Hypertension.
    JAMA internal medicine, 2020, 08-01, Volume: 180, Issue:8

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2020
Comparison of Clinical Outcomes and Safety Associated With Chlorthalidone vs Hydrochlorothiazide in Older Adults With Varying Levels of Kidney Function.
    JAMA network open, 2021, 09-01, Volume: 4, Issue:9

    Topics: Aged; Chlorthalidone; Drug-Related Side Effects and Adverse Reactions; Female; Glomerular Filtration Rate; Health Services for the Aged; Humans; Hydrochlorothiazide; Hypokalemia; Male; Ontario; Renal Insufficiency, Chronic; Sodium Chloride Symporter Inhibitors

2021
Hydrochlorothiazide Versus Chlorthalidone: What Is the Difference?
    Circulation, 2022, 11-29, Volume: 146, Issue:22

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2022
Pairwise comparison of hydrochlorothiazide and chlorthalidone responses among hypertensive patients.
    Clinical and translational science, 2022, Volume: 15, Issue:12

    Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Potassium; Thiazides

2022
The 'cold case' of chlortalidone vs. hydrochlorothiazide in hypertension closed by the diuretic comparison project?
    European heart journal, 2023, 04-01, Volume: 44, Issue:13

    Topics: Blood Pressure; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension

2023
In older adults with hypertension, chlorthalidone vs. hydrochlorothiazide did not reduce major CV events or deaths at 2.4 y.
    Annals of internal medicine, 2023, Volume: 176, Issue:4

    Topics: Aged; Antihypertensive Agents; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension

2023
Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events.
    The New England journal of medicine, 2023, Apr-06, Volume: 388, Issue:14

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2023
Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events.
    The New England journal of medicine, 2023, Apr-06, Volume: 388, Issue:14

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2023
Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events. Reply.
    The New England journal of medicine, 2023, Apr-06, Volume: 388, Issue:14

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2023
Chlorthalidone No Better Than Hydrochlorothiazide for Hypertension.
    American family physician, 2023, Volume: 108, Issue:3

    Topics: Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2023
[Chlorthalidone or hydrochlorothiazide as the first choice in the treatment of people with hypertension].
    Praxis, 2023, Volume: 112, Issue:10

    Topics: Antihypertensive Agents; Chlorthalidone; Humans; Hydrochlorothiazide; Hypertension

2023