hydrochlorothiazide and candesartan

hydrochlorothiazide has been researched along with candesartan in 74 studies

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's32 (43.24)29.6817
2010's39 (52.70)24.3611
2020's3 (4.05)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Barragan, J; Bernhardi, DC; Bunt, T; Cabrera, WJ; Dumortier, T; Grossman, E; Jacovides, A; Jelakovic, B; Manolis, AJ; Matadamas, N; Mejia, AD; Mendiola, A; Smith, RD; Watanabe, LA; Woo, KS; Zhu, JR1
Welch, WJ; Wilcox, CS1
Abe, I; Kagiyama, S; Lin, Y; Matsumura, K; Tsuchihashi, T1
Weisser, B1
Elmfeldt, D; Hansson, L; Hofman, A; Lithell, H; Olofsson, B; Skoog, I; Trenkwalder, P; Zanchetti, A1
Preobrazhenskiĭ, DV; Sidorenko, BA; Stetsenko, TM; Tarykina, EV; Tsurko, VV1
Bombelli, M; Dell'Oro, R; Facchini, A; Grassi, G; Mancia, G; Scopelliti, F; Seravalle, G; Trevano, FQ1
Arnolda, LF; Molloy, D; Upton, J; Wing, LM1
Degl'Innocenti, A; Elmfeldt, D; Hofman, A; Lithell, H; Olofsson, B; Skoog, I; Trenkwalder, P; Wiklund, I; Zanchetti, A1
Arakawa, K1
Williams, B1
Elmfeldt, D; Farsang, C; Hofman, A; Lithell, H; Olofsson, B; Papademetriou, V; Skoog, I; Trenkwalder, P; Zanchetti, A1
Mancia, G; Omboni, S1
Ijzerman, RG; Schalkwijk, CG; Schram, MT; Spoelstra-de Man, A; Stehouwer, CD; Twisk, JW; van Dijk, RA; van Ittersum, FJ1
Ishimitsu, T; Matsuoka, H; Minami, J1
Brouwer, CB; Ijzerman, RG; Kamp, O; Schram, MT; Spoelstra-de Man, AM; Stehouwer, CD; Twisk, JW; van Dijk, RA; van Ittersum, FJ1
Mengden, T; Tousset, E; Uen, S; Vetter, H1
Abe, C; Akashiba, A; Ishimitsu, T; Kameda, T; Matsuoka, H; Minami, J; Takahashi, T1
Corradi, L; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A1
Handrock, R; Hilsmann, U; Klebs, S; Neumann, G; Schweizer, J1
Fujita, T; Gohchi, K; Shimosawa, T; Yatomi, Y1
Audia, P; Dubrow, A; Feinfeld, DA; Winchester, JF1
Bramlage, P; Funken, C; Odoj, P; Schönrock, E; Wolf, WP1
Kato, N; Liang, YQ; Ochiai, Y; Serizawa, M1
Ahlström, H; Carlberg, B; Eriksson, JW; Hägg, A; Jansson, PA; Johansson, L; Kurland, L; Lind, L; Lönn, L; Ojbrandt, K; Ström, C; Svensson, MK1
Bramlage, P; Odoj, P; Schönrock, E1
Bönner, G1
Elmfeldt, D; Karlson, BW; Olofsson, B; Zetterstrand, S1
Borthen, C; Eggebøe, T; Ellingsen, CL; Oglaend, B; Schjøtt, J1
Eguchi, K; Hoshide, S; Kabutoya, T; Kario, K; Shimada, K1
Hosoya, T; Kuriyama, S; Otsuka, Y; Sugano, N; Ueda, H; Yamada, T; Yoshizawa, T1
Jin, D; Miyazaki, M; Sakonjo, H; Shimosato, T; Takai, S1
Benduhn, H; Klebs, S; Schweizer, J; Ulmer, HJ1
Eriksson, JW; Jansson, PA; Johansson, A; Johansson, L; Karlsson, C; Lind, L; Palming, J; Renström, F1
Nirnberger, G; Pittrow, LA; Slany, J1
Ishii, H; Kobayashi, S; Suzuki, O1
Bramlage, P; Hübner, R; Mengden, T1
Chen, YL; Chui, H; Hajjar, I; Hart, M; Lipsitz, L; Mack, W; Milberg, W1
Fujiwara, W; Ishii, J; Izawa, H; Kinoshita, K; Morimoto, S; Mukaide, D; Nomura, M; Ozaki, Y; Ukai, G; Yokoi, H1
Bailey, KR; Boerwinkle, E; Chai, HS; Chapman, AB; Schwartz, GL; Turner, ST1
Bharathi, DV; Chatki, PK; Hotha, KK; Satyanarayana, V; Venkateswarlu, V1
Cho, EJ; Choi, KY; Ihm, SH; Jang, SW; Kim, DB; Kim, JH; Kwon, BJ; Youn, HJ1
Akiyama, H; Hasegawa, Y1
Bailey, K; Boerwinkle, E; Chapman, AB; Schwartz, GL; Turner, ST1
Farinde, A1
Boomsma, F; Danser, AH; Schilders, JE; van den Meiracker, AH; Wu, H1
Abdel Monem Hegazy, M; Fayez, YM1
Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Donner, KM; Frau, F; Glorioso, N; Glorioso, V; Gong, Y; Gums, JG; Hiltunen, TP; Johnson, JA; Kontula, KK; Ripatti, S; Saarela, J; Salvi, E; Sarin, AP; Turner, ST; Zaninello, R1
Asayama, K; Hirose, T; Hosaka, M; Imai, Y; Inoue, R; Kikuya, M; Metoki, H; Obara, T; Ohkubo, T; Satoh, M1
Arora, A; Jain, S; Khuller, GK; Malhotra, S; Shafiq, N; Sharma, S1
Avezum, A; Bosch, J; Chazova, I; Dagenais, G; Dans, A; Diaz, R; Fodor, GJ; Held, C; Jansky, P; Keltai, K; Keltai, M; Kim, JH; Kunti, K; Leiter, L; Lewis, B; Liu, L; Lonn, E; Lopez-Jaramillo, P; Pais, P; Parkhomenko, A; Peters, RJ; Piegas, LS; Pogue, J; Reid, CM; Sliwa, K; Toff, WD; Varigos, J; Xavier, D; Yusoff, K; Yusuf, S; Zhu, J1
Accini, JL; Avezum, A; Bosch, J; Chazova, I; Dagenais, G; Dans, A; Diaz, R; Held, C; Jansky, P; Jung, H; Keltai, K; Keltai, M; Khunti, K; Leiter, LA; Lewis, BS; Liu, L; Lonn, E; López-Jaramillo, P; McKelvie, R; Pais, P; Parkhomenko, A; Peters, RJ; Piegas, LS; Pogue, J; Reid, CM; Sliwa, K; Toff, WD; Varigos, J; Xavier, D; Yusoff, K; Yusuf, S; Zhu, J1
Avezum, A; Bosch, J; Chazova, I; Dagenais, G; Dans, A; Diaz, R; Held, C; Jansky, P; Jung, H; Keltai, K; Keltai, M; Khunti, K; Leiter, LA; Lewis, BS; Liu, L; Lonn, EM; López-Jaramillo, P; McKelvie, R; Molina, DI; Pais, P; Parkhomenko, A; Peters, RJ; Piegas, LS; Pogue, J; Reid, CM; Sliwa, K; Toff, WD; Varigos, J; Wilkinson, J; Xavier, D; Yusoff, K; Yusuf, S; Zhu, J1
Ridker, PM1
Eaton Md, CB2
Alonso-Galicia, M; Corona, A; Felix, JP; Garcia, ML; Gill, C; Hampton, C; Kaczorowski, GJ; Kohler, M; Liu, J; Metzger, JM; Ormes, J; Owens, K; Pai, LY; Pasternak, A; Price, O; Priest, BT; Rasa, C; Roy, S; Shah, K; Sullivan, KA; Tang, H; Thomas-Fowlkes, B; Tong, V; Xiao, J; Zhou, X1
Danilov, SM; Dull, RO; Schwartz, DE; Tovsky, SI1
Bohm, M; Bosch, J; Dans, A; Joseph, P; Keltai, M; Khunti, K; Kim, JH; Lonn, E; Lopez, P; Piegas, L; Reid, C; Swaminathan, B; Toff, W; Yusuf, S; Zhu, J1
Avezum, A; Bogaty, PM; Bosch, J; Dagenais, GR; Dehghan, M; Held, C; Jansky, P; Jung, H; Keltai, M; Leiter, LA; Lonn, E; Lopez-Jaramillo, P; Toff, WD; Yusuf, S1
Ekman, I; Lind, L; Lytsy, P; Marttala, K; Nowrouzi, S; Öhagen, P; Östlund, O; Sundström, J1
Bosch, J; Dans, A; Jung, H; Kamath, D; Liu, L; Lonn, E; Pais, P; Yusuf, S; Zhu, J1
Bosch, J; Gafni, A; Jung, H; Lamy, A; Lonn, E; Swaminathan, B; Tong, W; Yusuf, S1
Avezum, A; Bosch, J; Dagenais, G; Dans, A; Diaz, R; Hart, R; Held, C; Keltai, M; Khunti, K; Lee, SF; Leiter, LA; Lewis, BS; Lonn, EM; O'Donnell, M; Pogue, JM; Reid, C; Sharma, M; Sliwa, K; Swaminathan, B; Toff, WD; Yusuf, S1
Bachmann, HS; Besser, M; Severing, AL; Stuermer, EK; Terberger, N1
Bhandari, RK; Bhatia, A; Kaur, N; Malhotra, S; Pandey, AK; Rather, IIG; Shafiq, N; Sharma, S1
Hagström, E; Held, C; Lind, L; Lytsy, P; Marttala, K; Neal, B; Nowrouzi, S; Östlund, O; Sundström, J1

Reviews

5 review(s) available for hydrochlorothiazide and candesartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Angiotensin I receptor antagonist losartan. Part II. Effects in arterial hypertension and diabetic nephropathy].
    Kardiologiia, 2003, Volume: 43, Issue:2

    Topics: Angiotensin I; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Meta-Analysis as Topic; Placebos; Prognosis; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2003
[Development of combined drugs (ARB and diuretics)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Design; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Kidney Tubules, Proximal; Losartan; Olmesartan Medoxomil; Practice Guidelines as Topic; Renin-Angiotensin System; Sodium; Telmisartan; Tetrazoles

2004
Protection against stroke and dementia: an update on the latest clinical trial evidence.
    Current hypertension reports, 2004, Volume: 6, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Cognition; Dementia; Hydrochlorothiazide; Ramipril; Stroke; Tetrazoles; Verapamil

2004
[Importance of a fixed combination of AT1-receptor blockade and hydrochlorothiazide for blood pressure lowering in cardiac risk patients. A postmarketing surveillance study with candesartan/HCTZ].
    MMW Fortschritte der Medizin, 2008, Feb-07, Volume: 150, Issue:6

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diuretics; Drug Combinations; Family Practice; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Practice Guidelines as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Treatment Outcome

2008

Trials

39 trial(s) available for hydrochlorothiazide and candesartan

ArticleYear
Effects of losartan and candesartan monotherapy and losartan/hydrochlorothiazide combination therapy in patients with mild to moderate hypertension. Losartan Trial Investigators.
    Clinical therapeutics, 2000, Volume: 22, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles

2000
The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial.
    Journal of hypertension, 2003, Volume: 21, Issue:5

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Cognition; Dementia; Dose-Response Relationship, Drug; Double-Blind Method; Europe; Female; Follow-Up Studies; Helsinki Declaration; Humans; Hydrochlorothiazide; Hypertension; Male; Prognosis; Prospective Studies; Risk Reduction Behavior; Severity of Illness Index; Survival Analysis; Tetrazoles; Time Factors; Treatment Outcome

2003
Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: results of the CROSS study.
    Journal of hypertension, 2003, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Obesity; Sympathetic Nervous System; Tetrazoles

2003
Candesartan and hydrochlorothiazide in isolated systolic hypertension.
    Blood pressure, 2003, Volume: 12, Issue:4

    Topics: Aged; Aged, 80 and over; Australia; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Clinical Protocols; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Selection; Sample Size; Tetrazoles; Time Factors; Treatment Outcome

2003
Health-related quality of life during treatment of elderly patients with hypertension: results from the Study on COgnition and Prognosis in the Elderly (SCOPE).
    Journal of human hypertension, 2004, Volume: 18, Issue:4

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cognition; Double-Blind Method; Europe; Female; Follow-Up Studies; Health Status Indicators; Humans; Hydrochlorothiazide; Hypertension; Male; Prognosis; Quality of Life; Tetrazoles; Treatment Outcome; United States

2004
Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE).
    Journal of the American College of Cardiology, 2004, Sep-15, Volume: 44, Issue:6

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Europe; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Receptor, Angiotensin, Type 1; Risk Factors; Stroke; Systole; Tetrazoles; Time Factors; Treatment Outcome

2004
Candesartan plus hydrochlorothiazide fixed combination vs previous monotherapy plus diuretic in poorly controlled essential hypertensive patients.
    Blood pressure. Supplement, 2004, Volume: 2

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure Determination; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oscillometry; Tetrazoles; Time Factors

2004
Aggressive antihypertensive therapy based on hydrochlorothiazide, candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals: effects on albumin excretion, endothelial function and inflammation in a double-blind, randomized c
    Journal of human hypertension, 2005, Volume: 19, Issue:6

    Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Hydrochlorothiazide; Hypertension; Inflammation; Lisinopril; Male; Middle Aged; Tetrazoles

2005
Aggressive antihypertensive strategies based on hydrochlorothiazide, candesartan or lisinopril decrease left ventricular mass and improve arterial compliance in patients with type II diabetes mellitus and hypertension.
    Journal of human hypertension, 2006, Volume: 20, Issue:8

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Compliance; Diabetes Mellitus, Type 2; Diastole; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Middle Aged; Organ Size; Systole; Tetrazoles; Ventricular Function, Left

2006
Management of patients with uncontrolled arterial hypertension--the role of electronic compliance monitoring, 24-h ambulatory blood pressure monitoring and Candesartan/HCTZ.
    BMC cardiovascular disorders, 2006, Aug-30, Volume: 6

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Drug Monitoring; Drug Therapy, Combination; Electronics, Medical; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Office Visits; Patient Compliance; Tetrazoles

2006
Long-term efficacy of combination therapy with losartan and low-dose hydrochlorothiazide in patients with uncontrolled hypertension.
    International heart journal, 2007, Volume: 48, Issue:2

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome

2007
Addition of manidipine improves the antiproteinuric effect of candesartan in hypertensive patients with type II diabetes and microalbuminuria.
    American journal of hypertension, 2007, Volume: 20, Issue:10

    Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nitrobenzenes; Piperazines; Prospective Studies; Proteinuria; Single-Blind Method; Tetrazoles

2007
Efficacy and safety of valsartan 160/HCTZ 25 mg in fixed combination in hypertensive patients not controlled by candesartan 32 mg plus HCTZ 25 mg in free combination.
    Current medical research and opinion, 2007, Volume: 23, Issue:11

    Topics: Benzimidazoles; Biphenyl Compounds; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Tetrazoles; Valine; Valsartan

2007
Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: losartan/hydrochlorothiazide vs. candesartan/amlodipine.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome

2007
[Importance of a fixed combination of AT1-receptor blockade and hydrochlorothiazide for blood pressure lowering in cardiac risk patients. A postmarketing surveillance study with candesartan/HCTZ].
    MMW Fortschritte der Medizin, 2008, Feb-07, Volume: 150, Issue:6

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diuretics; Drug Combinations; Family Practice; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Practice Guidelines as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Treatment Outcome

2008
Hydrochlorothiazide, but not Candesartan, aggravates insulin resistance and causes visceral and hepatic fat accumulation: the mechanisms for the diabetes preventing effect of Candesartan (MEDICA) Study.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Composition; Cross-Over Studies; Diabetes Mellitus, Type 2; Diuretics; Fatty Liver; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hyperinsulinism; Hypertension; Insulin Resistance; Intra-Abdominal Fat; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Tetrazoles

2008
Antihypertensive efficacy and tolerability of candesartan-hydrochlorothiazide 32/12.5 mg and 32/25 mg in patients not optimally controlled with candesartan monotherapy.
    Blood pressure. Supplement, 2008, Volume: 2

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Young Adult

2008
A dose-response analysis of candesartan-hydrochlorothiazide combination therapy in patients with hypertension.
    Blood pressure, 2009, Volume: 18, Issue:3

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Clinical Laboratory Techniques; Clinical Protocols; Diastole; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patients; Placebos; Research; Systole; Tetrazoles

2009
Efficacy and tolerability of aliskiren 300  mg/hydrochlorothiazide 25  mg (± amlodipine 5  mg) in hypertensive patients not controlled by candesartan 32  mg plus HCT 25  mg.
    Current medical research and opinion, 2011, Volume: 27, Issue:1

    Topics: Adult; Aged; Algorithms; Amides; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Failure; Treatment Outcome

2011
Hydrochlorothiazide compared to candesartan treatment increases adipose tissue gene expression and circulating levels of serum amyloid A in hypertensive patients.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2011, Volume: 43, Issue:5

    Topics: Adipose Tissue; Amyloid; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Gene Expression; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles

2011
Cardiovascular risk stratification and antihypertensive therapy according to guidelines in the outpatient setting.
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:23-24

    Topics: Age Factors; Aged; Ambulatory Care; Antihypertensive Agents; Austria; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Drug Therapy, Combination; Female; Guideline Adherence; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Assessment; Sex Factors; Tetrazoles; Treatment Outcome

2011
Office and ambulatory blood pressure control with a fixed-dose combination of candesartan and hydrochlorothiazide in previously uncontrolled hypertensive patients: results of CHILI CU Soon.
    Vascular health and risk management, 2011, Volume: 7

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Prospective Studies; Tetrazoles

2011
Effect of antihypertensive therapy on cognitive function in early executive cognitive impairment: a double-blind randomized clinical trial.
    Archives of internal medicine, 2012, Mar-12, Volume: 172, Issue:5

    Topics: Age Factors; Aged; Benzimidazoles; Biphenyl Compounds; Blood Pressure Determination; Cognition; Cognition Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Sex Factors; Tetrazoles; Treatment Outcome

2012
Low dose of hydrochlorothiazide, in combination with angiotensin receptor blocker, reduces blood pressure effectively without adverse effect on glucose and lipid profiles.
    Heart and vessels, 2013, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Lipids; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome

2013
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:6

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Black or African American; Blood Pressure; Case-Control Studies; Chi-Square Distribution; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 16; Diuretics; Drug Administration Schedule; Epithelial Sodium Channels; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Tetrazoles; White People

2012
Comparison of the efficacy between hydrochlorothiazide and chlorthalidone on central aortic pressure when added on to candesartan in treatment-naïve patients of hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:1

    Topics: Adult; Antihypertensive Agents; Arterial Pressure; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Vascular Stiffness

2013
Renin-angiotensin system phenotyping as a guidance toward personalized medicine for ACE inhibitors: can the response to ACE inhibition be predicted on the basis of plasma renin or ACE?
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:4

    Topics: Aged; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Phenotype; Precision Medicine; Renin; Renin-Angiotensin System; Tetrazoles

2014
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.
    Journal of the American Heart Association, 2015, Jan-26, Volume: 4, Issue:1

    Topics: Adult; Aldehyde Oxidoreductases; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Blood Pressure Monitoring, Ambulatory; Chloride Channels; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Essential Hypertension; Finland; Genome-Wide Association Study; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Membrane Proteins; Meta-Analysis as Topic; Microfilament Proteins; Middle Aged; Mutation, Missense; Pharmacogenetics; Polymorphism, Single Nucleotide; Severity of Illness Index; Tetrazoles; Treatment Outcome

2015
Randomized trial comparing the velocities of the antihypertensive effects on home blood pressure of candesartan and candesartan with hydrochlorothiazide.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Young Adult

2015
Novel Approaches in Primary Cardiovascular Disease Prevention: The HOPE-3 Trial Rationale, Design, and Participants' Baseline Characteristics.
    The Canadian journal of cardiology, 2016, Volume: 32, Issue:3

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Cholesterol, LDL; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Global Health; Humans; Hydrochlorothiazide; Incidence; Male; Middle Aged; Population Surveillance; Primary Prevention; Risk Factors; Rosuvastatin Calcium; Tetrazoles; Treatment Outcome

2016
Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease.
    The New England journal of medicine, 2016, May-26, Volume: 374, Issue:21

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Medication Adherence; Middle Aged; Risk Factors; Rosuvastatin Calcium; Tetrazoles

2016
Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease.
    The New England journal of medicine, 2016, May-26, Volume: 374, Issue:21

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Tetrazoles

2016
ACE Phenotyping as a Guide Toward Personalized Therapy With ACE Inhibitors.
    Journal of cardiovascular pharmacology and therapeutics, 2017, Volume: 22, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Monitoring; Drug Resistance; Drug Therapy, Combination; Enalapril; Genotype; Humans; Hydrochlorothiazide; Hypertension; Patient Selection; Peptidyl-Dipeptidase A; Pharmacogenetics; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Precision Medicine; Predictive Value of Tests; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome

2017
Long-term Effects of Statins, Blood Pressure-Lowering, and Both on Erectile Function in Persons at Intermediate Risk for Cardiovascular Disease: A Substudy of the Heart Outcomes Prevention Evaluation-3 (HOPE-3) Randomized Controlled Trial.
    The Canadian journal of cardiology, 2018, Volume: 34, Issue:1

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Libido; Male; Middle Aged; Penile Erection; Risk Factors; Rosuvastatin Calcium; Sexuality; Tetrazoles

2018
Effects of Lipid-Lowering and Antihypertensive Treatments in Addition to Healthy Lifestyles in Primary Prevention: An Analysis of the HOPE-3 Trial.
    Journal of the American Heart Association, 2018, 07-22, Volume: 7, Issue:15

    Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Female; Healthy Lifestyle; Humans; Hydrochlorothiazide; Male; Middle Aged; Primary Prevention; Risk Factors; Rosuvastatin Calcium; Tetrazoles; Treatment Outcome

2018
The Precision HYpertenSIon Care (PHYSIC) study: a double-blind, randomized, repeated cross-over study.
    Upsala journal of medical sciences, 2019, Volume: 124, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Precision Medicine; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Tetrazoles

2019
Impact of blood pressure lowering, cholesterol lowering and their combination in Asians and non-Asians in those without cardiovascular disease: an analysis of the HOPE 3 study.
    European journal of preventive cardiology, 2019, Volume: 26, Issue:7

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asia; Asian People; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Cholesterol, LDL; Double-Blind Method; Down-Regulation; Drug Combinations; Dyslipidemias; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Middle Aged; Rosuvastatin Calcium; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Treatment Outcome

2019
The cost implication of primary prevention in the HOPE 3 trial.
    European heart journal. Quality of care & clinical outcomes, 2019, 07-01, Volume: 5, Issue:3

    Topics: Antihypertensive Agents; Australia; Benzimidazoles; Biphenyl Compounds; Canada; Cardiovascular Diseases; Drug Combinations; Europe; Health Care Costs; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Primary Prevention; Rosuvastatin Calcium; Tetrazoles; United States

2019
Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs: A Randomized Clinical Trial.
    JAMA, 2023, 04-11, Volume: 329, Issue:14

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Precision Medicine

2023

Other Studies

31 other study(ies) available for hydrochlorothiazide and candesartan

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
AT1 receptor antagonist combats oxidative stress and restores nitric oxide signaling in the SHR.
    Kidney international, 2001, Volume: 59, Issue:4

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Combinations; Feedback; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Glomerulus; Kidney Tubules; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Reserpine; Signal Transduction; Tetrazoles; Transforming Growth Factors

2001
The influence of chronic antihypertensive treatment on the central pressor response in SHR.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Brain; Enalapril; Epinephrine; Heart Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Injections, Intraventricular; Losartan; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Saline Solution, Hypertonic; Tetrazoles

2001
[Report of experiences. Walk in the woods by a retiree without leg edema].
    MMW Fortschritte der Medizin, 2001, Oct-25, Volume: 143, Issue:43

    Topics: Benzimidazoles; Biphenyl Compounds; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Jogging; Lymphedema; Male; Middle Aged; Tetrazoles; Treatment Outcome

2001
[AT-1 blockers are different in their effects. The forgetful patients begin to notice it especially].
    MMW Fortschritte der Medizin, 2003, Apr-10, Volume: 145, Issue:15

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diuretics; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Losartan; Meta-Analysis as Topic; Placebos; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Stroke; Tetrazoles; Time Factors; Valine; Valsartan

2003
[Beneficial effects of combination therapy with losartan and low-dose hydrochlorothiazide in the treatment of essential hypertension].
    Nihon Jinzo Gakkai shi, 2005, Volume: 47, Issue:8

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles

2005
Metformin-induced lactic acidosis and acute pancreatitis precipitated by diuretic, celecoxib, and candesartan-associated acute kidney dysfunction.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:2

    Topics: Acidosis, Lactic; Acute Disease; Acute Kidney Injury; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Celecoxib; Cyclooxygenase Inhibitors; Diuretics; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Metformin; Middle Aged; Pancreatitis; Pharmaceutical Preparations; Polypharmacy; Pyrazoles; Renal Dialysis; Sodium Bicarbonate; Sulfonamides; Tetrazoles

2008
Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo.
    Physiological genomics, 2008, Nov-12, Volume: 35, Issue:3

    Topics: Animals; Benzimidazoles; Biphenyl Compounds; Dietary Fats; Diuretics; Enalapril; Gene Expression Regulation; Hydrochlorothiazide; Male; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride, Dietary; Tetrazoles

2008
Metabolic effects of an AT1-receptor blockade combined with HCTZ in cardiac risk patients: a non interventional study in primary care.
    BMC cardiovascular disorders, 2008, Nov-10, Volume: 8

    Topics: Abdominal Fat; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Cholesterol, HDL; Clinical Trials as Topic; Diuretics; Drug Interactions; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles

2008
Warnings against candesartan in pregnancy are not implemented in physicians' practice.
    European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 146, Issue:2

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Female; Fetal Death; Humans; Hydrochlorothiazide; Hypertension; Oligohydramnios; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications, Cardiovascular; Tetrazoles

2009
Is very low dose hydrochlorothiazide combined with candesartan effective in uncontrolled hypertensive patients?
    Blood pressure monitoring, 2010, Volume: 15, Issue:6

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Body Mass Index; Circadian Rhythm; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sleep; Tetrazoles

2010
Augmented antihypertensive effect of a fixed combination formula of candesartan and hydrochlorothiazide combined with furosemide in a patient on peritoneal dialysis.
    Clinical and experimental nephrology, 2011, Volume: 15, Issue:1

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Peritoneal Dialysis; Tetrazoles

2011
Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:2

    Topics: Acetylcholine; Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Vessels; Diuretics; Drug Therapy, Combination; Gene Expression Regulation; Hydrochlorothiazide; Male; Malondialdehyde; NADPH Oxidases; Rats; Rats, Inbred SHR; Rats, Wistar; Stroke; Superoxide Dismutase; Tetrazoles; Vasodilation; Vasodilator Agents

2011
Effects of an angiotensin 2 receptor blocker plus diuretic combination drug in chronic heart failure complicated by hypertension.
    The Journal of international medical research, 2011, Volume: 39, Issue:4

    Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chronic Disease; Diuretics; Drug Combinations; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Prognosis; Renin-Angiotensin System; Tetrazoles

2011
LC-MS/MS method for simultaneous estimation of candesartan and hydrochlorothiazide in human plasma and its use in clinical pharmacokinetics.
    Bioanalysis, 2012, Volume: 4, Issue:10

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Humans; Hydrochlorothiazide; Liquid-Liquid Extraction; Statistics, Nonparametric; Tandem Mass Spectrometry; Tetrazoles

2012
Migraine treated using a prophylactic combination of candesartan and hydrochlorothiazide (ECARD Combination Tablets LD).
    Pain practice : the official journal of World Institute of Pain, 2013, Volume: 13, Issue:7

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Combinations; Edema; Female; Humans; Hydrochlorothiazide; Leg; Middle Aged; Migraine Disorders; Tablets; Tetrazoles

2013
The role of plasma renin activity, age, and race in selecting effective initial drug therapy for hypertension.
    American journal of hypertension, 2013, Volume: 26, Issue:8

    Topics: Adult; Age Factors; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Black People; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Radioimmunoassay; Renin; Retrospective Studies; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; White People

2013
Drugs for treating hypertension.
    Nursing, 2013, Volume: 43, Issue:8

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drugs, Generic; Humans; Hydrochlorothiazide; Hypertension; Nifedipine; Prescription Drugs; Ramipril; Tetrazoles

2013
Mean centering of ratio spectra and concentration augmented classical least squares in a comparative approach for quantitation of spectrally overlapped bands of antihypertensives in formulations.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Apr-05, Volume: 140

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hydrochlorothiazide; Irbesartan; Least-Squares Analysis; Spectrophotometry; Tablets; Tetrazoles

2015
Development of Sustained Release "NanoFDC (Fixed Dose Combination)" for Hypertension - An Experimental Study.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Carriers; Drug Liberation; Half-Life; Hydrochlorothiazide; Hypertension; Lactic Acid; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Tetrazoles

2015
Is Statin Monotherapy the Perfect Polypill?
    Circulation, 2016, Jul-12, Volume: 134, Issue:2

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Drug Therapy, Combination; Dyslipidemias; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Multicenter Studies as Topic; Risk; Rosuvastatin Calcium; Tetrazoles

2016
Combination candesartan-HCTZ did not reduce major CV events in patients at intermediate CV risk.
    Annals of internal medicine, 2016, 07-19, Volume: 165, Issue:2

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles

2016
Adding candesartan-HCTZ to rosuvastatin increased adverse events but not benefits in patients at intermediate CV risk.
    Annals of internal medicine, 2016, 07-19, Volume: 165, Issue:2

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hydrochlorothiazide; Hypertension; Rosuvastatin Calcium; Tetrazoles

2016
The Renal Outer Medullary Potassium Channel Inhibitor, MK-7145, Lowers Blood Pressure, and Manifests Features of Bartter's Syndrome Type II Phenotype.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 359, Issue:1

    Topics: Animals; Bartter Syndrome; Benzimidazoles; Benzofurans; Biphenyl Compounds; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; HEK293 Cells; Humans; Hydrochlorothiazide; Male; Phenotype; Piperazines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Rats; Tetrazoles

2016
Effects of blood pressure and lipid lowering on cognition: Results from the HOPE-3 study.
    Neurology, 2019, 03-26, Volume: 92, Issue:13

    Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cognition; Cognitive Dysfunction; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypolipidemic Agents; Male; Rosuvastatin Calcium; Tetrazoles

2019
Side Effects of Frequently Used Antihypertensive Drugs on Wound Healing in vitro.
    Skin pharmacology and physiology, 2019, Volume: 32, Issue:3

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cell Line; Cell Movement; Diuretics; Fibroblasts; Humans; Hydrochlorothiazide; Keratinocytes; Metoprolol; Ramipril; Tetrazoles; Wound Healing

2019
Pharmacokinetic and pharmacodynamic evaluation of nano-fixed dose combination for hypertension.
    Journal of hypertension, 2020, Volume: 38, Issue:8

    Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Drug Combinations; Hydrochlorothiazide; Hypertension; Male; Nanoparticles; Rats; Rats, Wistar; Tetrazoles

2020