hydrochlorothiazide and bumetanide

hydrochlorothiazide has been researched along with bumetanide in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.11)18.7374
1990's10 (27.78)18.2507
2000's9 (25.00)29.6817
2010's12 (33.33)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Grassl, SM; Holtzman, EJ; Race, JE; Williams, WJ1
Topliss, JG; Yoshida, F1
Hashimoto, Y; Inui, KI; Saito, H; Uwai, Y1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andricopulo, AD; Moda, TL; Montanari, CA1
Cecchi, A; Scozzafava, A; Supuran, CT; Temperini, C1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bottà, G; Cremaschi, D; Meyer, G; Porta, C1
Anagnostopoulos, T; Planelles, G1
Kazlauskas, R; Lisi, AM; Trout, GJ1
Knepper, MA; Terada, Y1
Basile, AS; Lueddens, HW; Skolnick, P1
Beermann, B1
Brunkhorst, R; Franke, H; Gutsche, HU; Müller-Ott, K; Niedermayer, W1
Wester, PO1
Bowler, JM; Butt, AG; Macknight, AD; McLaughlin, CW; Purves, RD1
Betz, AL; Ennis, SR; Ren, XD1
Carstens, S; Frederiksen, O; Holm, M; Röpke, M1
Dörschner, N; Groth, J; Wiederholt, M1
Crowder, MA; Gerencser, GA; Loughlin, GM1
Christensen, RJ; Ianowski, JP; O'Donnell, MJ1
Li, ST; Li, Y; Sun, CJ; Wang, Y; Zhang, WT1
Fu, A; Reagan, JD; Wu, X; Yang, Y1
Brockmöller, J; Dalila, N; Haubrock, M; Schirmer, M; Tzvetkov, MV; Vormfelde, SV1
Denton, JS; Flores, D; Kharade, SV; Lindsley, CW; Satlin, LM1
Aubry, M; Girerd, N; Huttin, O; Lantelme, P; Rossignol, P1

Reviews

2 review(s) available for hydrochlorothiazide and bumetanide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Aspects on pharmacokinetics of some diuretics.
    Acta pharmacologica et toxicologica, 1984, Volume: 54 Suppl 1

    Topics: Amiloride; Bendroflumethiazide; Bumetanide; Chlorthalidone; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Kinetics; Sodium Chloride Symporter Inhibitors; Spironolactone

1984

Trials

2 trial(s) available for hydrochlorothiazide and bumetanide

ArticleYear
Urinary zinc excretion during treatment with different diuretics.
    Acta medica Scandinavica, 1980, Volume: 208, Issue:3

    Topics: Adult; Aged; Bendroflumethiazide; Bumetanide; Chlorthalidone; Clinical Trials as Topic; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation; Triamterene; Zinc

1980
Impact of mineralocorticoid receptor polymorphisms on urinary electrolyte excretion with and without diuretic drugs.
    Pharmacogenomics, 2015, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Bumetanide; Cross-Over Studies; Diuretics; Electrolytes; Furosemide; Genetic Association Studies; Humans; Hydrochlorothiazide; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Potassium; Receptors, Mineralocorticoid; Single-Blind Method; Sodium Chloride; Sulfonamides; Torsemide; Triamterene; Young Adult

2015

Other Studies

32 other study(ies) available for hydrochlorothiazide and bumetanide

ArticleYear
Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3).
    Biochemical and biophysical research communications, 1999, Feb-16, Volume: 255, Issue:2

    Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Blotting, Northern; Carrier Proteins; Chromosomes, Human, Pair 11; Cloning, Molecular; Humans; Kidney; Mice; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Sequence Homology, Amino Acid; Xenopus laevis

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Acetazolamide; Animals; Anion Transport Proteins; Biological Transport; Bumetanide; Carrier Proteins; Diuretics; Furosemide; Hydrochlorothiazide; Kidney Tubules; Organotechnetium Compounds; Rats

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.
    Bioorganic & medicinal chemistry letters, 2008, Apr-15, Volume: 18, Issue:8

    Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Computer Simulation; Crystallography, X-Ray; Humans; Indapamide; Isoenzymes; Mice; Models, Molecular; Molecular Structure

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Nature of the neutral Na(+)-Cl- coupled entry at the apical membrane of rabbit gallbladder epithelium: IV. Na+/H+, Cl-/HCO3- double exchange, hydrochlorothiazide-sensitive Na(+)-Cl- symport and Na(+)-K(+)-2Cl- cotransport are all involved.
    The Journal of membrane biology, 1992, Volume: 129, Issue:3

    Topics: Animals; Bicarbonates; Biological Transport; Bumetanide; Carrier Proteins; Cell Membrane; Chlorides; Epithelium; Gallbladder; Hydrochlorothiazide; Membrane Potentials; Potassium; Rabbits; Sodium; Sodium Chloride; Sodium Chloride Symporters; Symporters

1992
Thiazide-sensitive Na-Cl cotransport mediates NaCl absorption in amphibian distal tubule.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 421, Issue:4

    Topics: Amiloride; Animals; Bumetanide; Carrier Proteins; Furosemide; Hydrochlorothiazide; Kidney Tubules, Distal; Necturus; Sodium Chloride; Sodium Chloride Symporters; Symporters

1992
Screening for diuretics in human urine by gas chromatography-mass spectrometry with derivatisation by direct extractive alkylation.
    Journal of chromatography, 1991, Feb-15, Volume: 563, Issue:2

    Topics: Acetazolamide; Alkylation; Bumetanide; Chlorothiazide; Diuretics; Ethacrynic Acid; Gas Chromatography-Mass Spectrometry; Humans; Hydrochlorothiazide

1991
Thiazide-sensitive NaCl absorption in rat cortical collecting duct.
    The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 2

    Topics: Absorption; Amiloride; Animals; Biological Transport; Bumetanide; Chlorides; Hydrochlorothiazide; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Male; Ouabain; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride

1990
Regulation of renal peripheral benzodiazepine receptors by anion transport inhibitors.
    Life sciences, 1988, Volume: 42, Issue:6

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Amiloride; Animals; Anions; Anthracenes; Biological Transport; Bumetanide; Furosemide; Hydrochlorothiazide; Kidney; Kinetics; Male; Myocardium; Ouabain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spironolactone

1988
Effect of diuretics on the tubuloglomerular feedback response.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:4

    Topics: Animals; Body Weight; Bumetanide; Diuretics; Feedback; Furosemide; Hydrochlorothiazide; Kidney Glomerulus; Kidney Tubules; Lissamine Green Dyes; Male; Organ Size; Rats; Rats, Inbred Strains; Sulfonamides

1984
Cell Cl and transepithelial na transport in toad urinary bladder.
    The Journal of membrane biology, 1994, Volume: 142, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Antiporters; Bendroflumethiazide; Bufo marinus; Bumetanide; Cell Size; Chloride-Bicarbonate Antiporters; Chlorides; Culture Media; Electron Probe Microanalysis; Epithelial Cells; Epithelium; Gluconates; Hydrochlorothiazide; Intracellular Fluid; Membrane Potentials; Nitrobenzoates; Sodium; Urinary Bladder

1994
Mechanisms of sodium transport at the blood-brain barrier studied with in situ perfusion of rat brain.
    Journal of neurochemistry, 1996, Volume: 66, Issue:2

    Topics: Amiloride; Animals; Biological Transport; Blood-Brain Barrier; Brain; Bumetanide; Carrier Proteins; Cerebrovascular Circulation; Frontal Lobe; Hydrochlorothiazide; Kinetics; Perfusion; Plasma Volume; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters

1996
Ion transport mechanisms in native rabbit nasal airway epithelium.
    The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 1

    Topics: Amiloride; Animals; Barium; Biological Transport; Bumetanide; Chloride Channels; Chlorides; Electrophysiology; Epithelium; Hydrochlorothiazide; Nasal Mucosa; ortho-Aminobenzoates; Potassium Channel Blockers; Rabbits; Sodium; Sodium Channels; Water-Electrolyte Balance

1996
Effect of diuretics, channel modulators and signal interceptors on contractility of the trabecular meshwork.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1997, Volume: 211, Issue:3

    Topics: Absorption; Animals; Anterior Eye Segment; Aqueous Humor; Bumetanide; Carbachol; Cattle; Cells, Cultured; Ciliary Body; Cytochalasin D; Diuretics; Ethacrynic Acid; Hydrochlorothiazide; Ion Channels; Isometric Contraction; Muscle, Smooth; Parasympathomimetics; Patch-Clamp Techniques; Perfusion; Signal Transduction; Trabecular Meshwork

1997
Chloride transport in the ferret trachea.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 1999, Volume: 122, Issue:1

    Topics: Animals; Anthracenes; Biological Transport; Bumetanide; Carbachol; Chloride Channels; Chlorides; Cholinergic Agonists; Diuretics; Enzyme Inhibitors; Epithelial Cells; Ferrets; Hydrochlorothiazide; Male; Ouabain; Sodium Chloride Symporter Inhibitors; Trachea

1999
Na+ competes with K+ in bumetanide-sensitive transport by Malpighian tubules of Rhodnius prolixus.
    The Journal of experimental biology, 2004, Volume: 207, Issue:Pt 21

    Topics: Analysis of Variance; Animals; Bumetanide; Hydrochlorothiazide; Ion Transport; Malpighian Tubules; Membrane Potentials; Microelectrodes; Potassium; Rhodnius; Serotonin; Sodium; Sodium-Potassium-Chloride Symporters

2004
[Simultaneous determination of five illegal drugs in weight control foods with solid phase extraction-high performance liquid chromatography].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:5

    Topics: Bumetanide; Chromatography, High Pressure Liquid; Clopamide; Cyclobutanes; Food Contamination; Food, Formulated; Furosemide; Hydrochlorothiazide; Sensitivity and Specificity; Solid Phase Extraction

2010
GPR35 is a target of the loop diuretic drugs bumetanide and furosemide.
    Pharmacology, 2012, Volume: 89, Issue:1-2

    Topics: Animals; Bumetanide; Calcium; Chlorothiazide; CHO Cells; Cricetinae; Diuretics; Furosemide; HEK293 Cells; HT29 Cells; Humans; Hydrochlorothiazide; Inositol Phosphates; Mice; Rats; Receptors, G-Protein-Coupled; Skin; Transfection

2012
ROMK inhibitor actions in the nephron probed with diuretics.
    American journal of physiology. Renal physiology, 2016, 04-15, Volume: 310, Issue:8

    Topics: Amiloride; Animals; Benzimidazoles; Bumetanide; Diuresis; Diuretics; Drug Interactions; Hydrochlorothiazide; Nephrons; Potassium; Potassium Channels, Inwardly Rectifying; Rats; Sodium

2016
Intravenous Mineralocorticoid Receptor Antagonist Use in Acutely Decompensated Heart Failure with Diuretic Resistance.
    International heart journal, 2021, Jan-30, Volume: 62, Issue:1

    Topics: Administration, Intravenous; Aged; Aged, 80 and over; Bumetanide; Canrenoic Acid; Creatinine; Diuresis; Diuretics; Drug Combinations; Drug Resistance; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Mineralocorticoid Receptor Antagonists; Potassium; Treatment Outcome

2021