hydrochlorothiazide and benazepril

hydrochlorothiazide has been researched along with benazepril in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.45)18.7374
1990's11 (15.94)18.2507
2000's33 (47.83)29.6817
2010's24 (34.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Nordrehaug, JE; Omsjø, IH; Vollset, SE1
DeQuattro, V1
Abraham, PA; Bennett, WM; Brachfeld, N; Goodman, RP; Hollifield, JW; Kirkendall, WM; Lasseter, KC; Leon, AS; McKenney, JM; Moser, M1
Whalen, JJ1
Nordrehaug, JE; Vollset, SE1
Fogari, R; Lusardi, P; Motolese, M; Tettamanti, F; Tettamanzi, D; Zoppi, A2
Chrysant, SG; Fagan, T; Glazer, R; Kriegman, A1
Panderi, IE; Parissi-Poulou, M1
Panderi, IE1
Erk, N1
Abdine, HH; El-Yazbi, FA; Shaalan, RA1
Cohen, D; Dao, T; Dargere, S; Galais, MP; Hourmand-Ollivier, I; Mosquet, B; Rousselot, P1
Abdel-Fattah, L; Ashour, A; El-Gindy, A; Shabana, MM2
Bedigian, MP; Neutel, JM; Smith, DH; Weir, MR1
Aschwanden, R; Ferber, P; Sadecky, L; Waeber, B1
Bertocchi, F; Carretta, R; Di Somma, S; Malacco, E; Mugellini, A; Palatini, P; Piazza, S1
Bakris, GL; McCullough, PA; Toto, RD1
Weder, AB1
Kazanis, M; Panderi, I; Vonaparti, A1
Chavanu, K; Merkel, J; Quan, A1
Franceschi, L; Furlanut, M; Pecorari, M; Poz, D; Silvestri, L1
Jaimes, EA; Raij, L; Zhou, MS1
Bakris, GL; Dahlöf, B; Gupte, J; Hester, A; Jamerson, K; Kjeldsen, S; Lefkowitz, M; Massie, B; Nesbitt, S; Ofili, E; Pitt, B; Shi, V; Velazquez, E; Weber, MA; Weir, M1
Bakris, GL; Cushman, W; Dahlöf, B; Gupte, J; Hester, A; Jamerson, K; Kjeldsen, SE; Lefkowitz, M; Papademetriou, V; Pitt, B; Shi, V; Velazquez, E; Weber, M1
Dubiel, R; Kereiakes, DJ; Lipka, LJ; Neutel, JM; Punzi, HA; Xu, J1
Bakris, GL; Davis, P; McCullough, PA; Purkayastha, D; Rocha, R; Toto, RD1
Einecke, D1
Bakris, GL; Dahlöf, B; Gupte, J; Hester, A; Hua, TA; Ibsen, H; Jamerson, KA; Kjeldsen, SE; Ostergren, J; Pitt, B; Shi, V; Staikos, L; Tuomilehto, J; Velazquez, EJ; Weber, M1
Aumiller, J1
Bakris, G; Dahlof, B; Hester, A; Jamerson, K; Pitt, B; Shi, V; Staikos-Byrne, L; Velasquez, E; Weber, M1
Bakris, GL; Dahlöf, B; Gatlin, M; Gupte, J; Hester, A; Jamerson, K; Pitt, B; Shi, V; Velazquez, EJ; Weber, MA1
Chobanian, AV1
Basile, JN; Carter, BL; Ernst, ME1
Feihl, F; Waeber, B1
Cohen, DL; Townsend, RR1
Preobrazhenskiĭ, DV1
Parra, D; Rosenstein, R1
Newton, GE; Strauss, MH; Weinstein, J1
Davis, BR; Whelton, PK1
Turnbull, F1
Siragy, HM1
Devereux, RB; Hall, D; Hilkert, R; Pitt, B; Purkayastha, D; Reichek, N; Rocha, RA1
Bakris, GL; Chiang, YT; Dahlöf, B; Jamerson, K; Kelly, RY; Pitt, B; Sarafidis, PA; Shi, V; Staikos-Byrne, L; Velazquez, EJ; Weber, MA; Weir, MR1
de Zeeuw, D; Heerspink, HL1
Bakris, GL; Jamerson, KA; Weber, MA1
Bakris, GL; Dahlöf, B; Devereux, RB; Hester, A; Hua, TA; Jamerson, K; Kelly, RY; Kjeldsen, SE; Pitt, B; Velazquez, EJ; Weber, MA; Weir, M1
Bakris, GL; Dahlöf, B; Devereux, R; Hester, A; Hua, TA; Jamerson, KA; Kelly, RY; Pitt, B; Velazquez, EJ; Weber, MA; Weir, M1
Bakris, GL; Dahlöf, B; Hester, A; Hua, TA; Ibsen, H; Jamerson, KA; Kelly, RY; Kjeldsen, SE; Ostergren, J; Pitt, B; Tuomilehto, J; Velazquez, EJ; Weber, M; Zappe, D1
Huang, Y; Jiang, J; Li, Y; Liu, H; Tian, L; Xie, S; Xu, L1
Bakris, GL; Dahlof, B; Devereux, RB; Hester, RA; Hua, TA; Jamerson, KA; Kelly, RY; Kjeldsen, SE; Pitt, B; Velazquez, E; Weber, MA; Weir, MR; Wright, JT1
Chen, JF; Hung, YJ; Lee, IT; Lee, WJ; Sheu, WH; Wang, CY2
Bakris, GL; Dahlof, B; Jamerson, K; Pitt, B; Velazquez, EJ; Weber, MA; Weir, MR; Zappe, D; Zhang, Y1
Bakris, G; Briasoulis, A; Dahlof, B; Hester, A; Hua, T; Jamerson, K; Kelly, RY; Pitt, B; Weber, MA; Zappe, D1
Friedman, RL; Hoehns, JD; Lallier, TS; McDougall, DJ1
Bakris, G; Byrd, JB; Jamerson, K1
Abdelaleem, EA; Draz, ME; Naguib, IA; Zaazaa, HE2
Asp, J; Dahlöf, B; Jamerson, KA; Jia, Y; Kjeldsen, SE; Östergren, J; Skoglund, PH; Svensson, P; Weber, MA; Zappe, DH1
Bakris, G; Brook, RD; Dahlöf, B; Hau, T; Jamerson, KA; Kaciroti, N; Pitt, B; Velazquez, E; Weber, M; Zappe, DH1
Mahrouse, MA1
Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M1

Reviews

4 review(s) available for hydrochlorothiazide and benazepril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Comparison of benazepril and other antihypertensive agents alone and in combination with the diuretic hydrochlorothiazide.
    Clinical cardiology, 1991, Volume: 14, Issue:8 Suppl 4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension

1991
A review of the efficacy of fixed-dose combinations olmesartan medoxomil/hydrochlorothiazide and amlodipine besylate/benazepril in factorial design studies.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2006, Volume: 6, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Drug Therapy, Combination; Factor Analysis, Statistical; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles

2006
The contribution of the ACCOMPLISH trial to the treatment of stage 2 hypertension.
    Current hypertension reports, 2014, Volume: 16, Issue:3

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Practice Guidelines as Topic; Randomized Controlled Trials as Topic

2014

Trials

33 trial(s) available for hydrochlorothiazide and benazepril

ArticleYear
A 3-month double-blind cross-over study of the effect of benazepril and hydrochlorothiazide on functional class in symptomatic mild heart failure.
    Journal of internal medicine, 1992, Volume: 231, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Double-Blind Method; Female; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Time Factors

1992
The effects of benazepril, a new angiotensin-converting enzyme inhibitor, in mild to moderate essential hypertension: a multicenter study.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:3

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Black People; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin

1991
Definition of the effective dose of the converting-enzyme inhibitor benazepril.
    American heart journal, 1989, Volume: 117, Issue:3

    Topics: Benzazepines; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Prodrugs; Random Allocation

1989
Reduction of exercise-induced ventricular arrhythmias in mild symptomatic heart failure by benazepril.
    American heart journal, 1993, Volume: 125, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiac Complexes, Premature; Double-Blind Method; Electrocardiography, Ambulatory; Exercise; Exercise Test; Heart Failure; Humans; Hydrochlorothiazide; Myocardial Infarction; Tachycardia, Ventricular

1993
Evaluation by 24-hour ambulatory blood pressure monitoring of efficacy of benazepril 20 mg plus hydrochlorothiazide 25 mg fixed combination as compared to captopril 50 mg [corrected] plus hydrochlorothiazide 25 mg fixed combination in treating mild to mod
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:5

    Topics: Administration, Oral; Adult; Analysis of Variance; Antihypertensive Agents; Benzazepines; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Outpatients

1994
Fixed combination of benazepril and very low dose hydrochlorothiazide in the treatment of mild to moderate essential hypertension: evaluation by 24-hour non invasive ambulatory blood pressure monitoring.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:11

    Topics: Adult; Aged; Antihypertensive Agents; Benzazepines; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1994
Effects of benazepril and hydrochlorothiazide, given alone and in low- and high-dose combinations, on blood pressure in patients with hypertension.
    Archives of family medicine, 1996, Volume: 5, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome

1996
Valsartan alone or with a diuretic or ACE inhibitor as treatment for African American hypertensives: relation to salt intake.
    American journal of hypertension, 2001, Volume: 14, Issue:7 Pt 1

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Black People; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pilot Projects; Prospective Studies; Sodium Chloride Symporter Inhibitors; Sodium, Dietary; Tetrazoles; Valine; Valsartan

2001
Combination of hydrochlorothiazide or benazepril with valsartan in hypertensive patients unresponsive to valsartan alone.
    Journal of hypertension, 2001, Volume: 19, Issue:11

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Diuretics; Drug Combinations; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan

2001
Comparison of benazepril-amlodipine and captopril-thiazide combinations in the management of mild-to-moderate hypertension.
    International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:6

    Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Captopril; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

2002
Rationale and design of a study comparing two fixed-dose combination regimens to reduce albuminuria in patients with type II diabetes and hypertension.
    Journal of human hypertension, 2005, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Renin-Angiotensin System; Research Design; Sodium Chloride Symporter Inhibitors

2005
Baseline characteristics in the Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: a hypertensive population at high cardiovascular risk.
    Blood pressure, 2007, Volume: 16, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Myocardial Infarction; Patient Selection; Scandinavian and Nordic Countries; Stroke; United States

2007
Exceptional early blood pressure control rates: the ACCOMPLISH trial.
    Blood pressure, 2007, Volume: 16, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension

2007
Efficacy and safety of olmesartan medoxomil and hydrochlorothiazide compared with benazepril and amlodipine besylate.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2007, Volume: 7, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Diastole; Drug-Related Side Effects and Adverse Reactions; Female; Goals; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Systole; Tetrazoles; Treatment Outcome

2007
Effects of different ACE inhibitor combinations on albuminuria: results of the GUARD study.
    Kidney international, 2008, Volume: 73, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome

2008
Predictors of blood pressure response to intensified and fixed combination treatment of hypertension: the ACCOMPLISH study.
    Blood pressure, 2008, Volume: 17, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Finland; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Racial Groups; Risk Assessment; Scandinavian and Nordic Countries; Treatment Outcome; United States

2008
The diabetes subgroup baseline characteristics of the Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial.
    Journal of the cardiometabolic syndrome, 2008,Fall, Volume: 3, Issue:4

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prevalence; Time Factors; Treatment Outcome; United States

2008
Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients.
    The New England journal of medicine, 2008, Dec-04, Volume: 359, Issue:23

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Risk

2008
[Is the combination of benazepril and amlodipine more effective in hypertension than the combination of benazepril and hydrochlorothiazide? Results of the ACCOMPLISH trial].
    Kardiologiia, 2009, Volume: 49, Issue:2

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Treatment Outcome

2009
ACCOMPLISH the goal: hypertension and beyond.
    Current hypertension reports, 2009, Volume: 11, Issue:4

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Risk Assessment

2009
Magnetic resonance imaging left ventricular mass reduction with fixed-dose angiotensin-converting enzyme inhibitor-based regimens in patients with high-risk hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Male; Middle Aged; Risk Factors; Sex Characteristics; Treatment Outcome

2009
Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial.
    Lancet (London, England), 2010, Apr-03, Volume: 375, Issue:9721

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Creatinine; Disease Progression; Diuretics; Double-Blind Method; Drug Combinations; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Risk Factors

2010
24-hour ambulatory blood pressure in the ACCOMPLISH trial.
    The New England journal of medicine, 2010, Jul-01, Volume: 363, Issue:1

    Topics: Amlodipine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension

2010
Cardiovascular events during differing hypertension therapies in patients with diabetes.
    Journal of the American College of Cardiology, 2010, Jun-29, Volume: 56, Issue:1

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Coronary Disease; Diabetes Complications; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Risk Factors

2010
Efficacy and duration of benazepril plus amlodipine or hydrochlorothiazide on 24-hour ambulatory systolic blood pressure control.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:2

    Topics: Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Benzazepines; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome

2011
Predictors of systolic BP <140 mmHg and systolic BP level by randomly assigned treatment group (benazepril plus amlodipine or hydrochlorothiazide) in the ACCOMPLISH Study.
    Blood pressure, 2012, Volume: 21, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydrochlorothiazide; Hypertension; Logistic Models; Male; Systole

2012
Pharmacokinetic profiles of hydrochlorothiazide alone and in combination with benazepril or valsartan in healthy Chinese volunteers: evaluation of the potential interaction.
    International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:12

    Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cross-Over Studies; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2011
Renal outcomes in hypertensive Black patients at high cardiovascular risk.
    Kidney international, 2012, Volume: 81, Issue:6

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Biomarkers; Black or African American; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Chi-Square Distribution; Creatinine; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Incidence; Kaplan-Meier Estimate; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; United States; Up-Regulation

2012
Comparison of the efficacy and safety profiles of two fixed-dose combinations of antihypertensive agents, amlodipine/benazepril versus valsartan/hydrochlorothiazide, in patients with type 2 diabetes mellitus and hypertension: a 16-week, multicenter, rando
    Clinical therapeutics, 2012, Volume: 34, Issue:8

    Topics: Aged; Albuminuria; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Treatment Outcome; Uric Acid; Valine; Valsartan

2012
Effects of body size and hypertension treatments on cardiovascular event rates: subanalysis of the ACCOMPLISH randomised controlled trial.
    Lancet (London, England), 2013, Feb-16, Volume: 381, Issue:9866

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Body Mass Index; Body Size; Body Weight; Cardiovascular Diseases; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity

2013
Comparison of benazepril plus amlodipine or hydrochlorothiazide in high-risk patients with hypertension and coronary artery disease.
    The American journal of cardiology, 2013, Jul-15, Volume: 112, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Risk Assessment

2013
Amlodipine+benazepril is superior to hydrochlorothiazide+benazepril irrespective of baseline pulse pressure: subanalysis of the ACCOMPLISH trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Myocardial Infarction; Retrospective Studies; Risk Factors; Stroke; Treatment Outcome

2015
Assessment of glomerular filtration rate based on alterations of serum brain-derived neurotrophic factor in type 2 diabetic subjects treated with amlodipine/benazepril or valsartan/hydrochlorothiazide.
    Disease markers, 2015, Volume: 2015

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Male; Middle Aged; Valsartan

2015

Other Studies

32 other study(ies) available for hydrochlorothiazide and benazepril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Simultaneous determination of benazepril hydrochloride and hydrochlorothiazide by micro-bore liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 21, Issue:5

    Topics: Antihypertensive Agents; Benzazepines; Calibration; Chromatography, High Pressure Liquid; Drug Combinations; Hydrochlorothiazide; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Powders; Reproducibility of Results; Sensitivity and Specificity; Tablets

1999
Simultaneous determination of benazepril hydrochloride and hydrochlorothiazide in tablets by second-order derivative spectrophotometry.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 21, Issue:2

    Topics: Antihypertensive Agents; Benzazepines; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Molecular Structure; Quality Control; Spectrophotometry, Ultraviolet; Tablets

1999
Determination of active ingredients in the pharmaceutical formulations containing hydrochlorothiazide and its binary mixtures with benazepril hydrochloride, triamterene and cilazapril by ratio spectra derivative spectrophotometry and vierordt's method.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 20, Issue:1-2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cilazapril; Diuretics; Drug Combinations; Hydrochlorothiazide; Indicators and Reagents; Sodium Chloride Symporter Inhibitors; Solvents; Spectrophotometry, Ultraviolet; Tablets; Triamterene

1999
Spectrophotometric methods for the determination of benazepril hydrochloride in its single and multi-component dosage forms.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 20, Issue:1-2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Bromcresol Green; Diuretics; Drug Combinations; Drug Stability; Hydrazones; Hydrochlorothiazide; Indicators and Reagents; Reproducibility of Results; Sodium Chloride Symporter Inhibitors; Solutions; Spectrophotometry, Ultraviolet; Tablets; Thiazoles

1999
[Fatal subfulminant hepatitis probably due to the combination benazepril-hydrochlorothiazide (Briazide)].
    Gastroenterologie clinique et biologique, 2000, Volume: 24, Issue:4

    Topics: Aged; Antihypertensive Agents; Benzazepines; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Interactions; Fatal Outcome; Female; Humans; Hydrochlorothiazide

2000
Application of LC and HPTLC-densitometry for the simultaneous determination of benazepril hydrochloride and hydrochlorothiazide.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 25, Issue:2

    Topics: Antihypertensive Agents; Benzazepines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Hydrochlorothiazide; Indicators and Reagents; Reference Standards; Solutions; Tablets

2001
Spectrophotometric determination of benazepril hydrochloride and hydrochlorothiazide in binary mixture using second derivative, second derivative of the ratio spectra and chemometric methods.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 25, Issue:2

    Topics: Antihypertensive Agents; Benzazepines; Calibration; Drug Combinations; Hydrochlorothiazide; Indicators and Reagents; Least-Squares Analysis; Reference Standards; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet; Tablets

2001
The Avoiding Cardiovascular events through COMbination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: a comparison of first-line combination therapies.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Risk Factors

2005
Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the determination of benazepril, benazeprilat and hydrochlorothiazide in human plasma.
    Journal of mass spectrometry : JMS, 2006, Volume: 41, Issue:5

    Topics: Antihypertensive Agents; Benzazepines; Calibration; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2006
Acute oxcarbazepine, benazepril, and hydrochlorothiazide overdose with alcohol.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:2

    Topics: Anticonvulsants; Antihypertensive Agents; Benzazepines; Carbamazepine; Critical Care; Diuretics; Drug Overdose; Humans; Hydrochlorothiazide; Male; Middle Aged; Oxcarbazepine; Recovery of Function; Renal Dialysis; Tablets; Time Factors; Wine

2006
Benazepril combined with either amlodipine or hydrochlorothiazide is more effective than monotherapy for blood pressure control and prevention of end-organ injury in hypertensive Dahl rats.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:1

    Topics: Acetylcholine; Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Drug Therapy, Combination; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Vasodilation

2006
[Amlodipine is the better partner].
    MMW Fortschritte der Medizin, 2008, Apr-17, Volume: 150, Issue:16

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Randomized Controlled Trials as Topic; Treatment Outcome

2008
[Unexpected study data for treatment of hypertension. Combination therapy with a diuretic not imperative].
    MMW Fortschritte der Medizin, 2008, Jun-05, Volume: 150, Issue:23

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Cardiovascular Diseases; Cause of Death; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Survival Analysis

2008
Does it matter how hypertension is controlled?
    The New England journal of medicine, 2008, Dec-04, Volume: 359, Issue:23

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Risk

2008
All thiazide-like diuretics are not chlorthalidone: putting the ACCOMPLISH study into perspective.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Chlorthalidone; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

2009
[The ACCOMPLISH trial: are results really unexpected?].
    Revue medicale suisse, 2009, Jan-07, Volume: 5, Issue:185

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Calcium Channel Blockers; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic

2009
Will the results of the ACCOMPLISH trial affect the recommendations of JNC 8?
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:2

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Practice Guidelines as Topic; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome

2009
Benazepril plus amlodipine or hydrochlorothiazide for hypertension.
    The New England journal of medicine, 2009, Mar-12, Volume: 360, Issue:11

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia

2009
Benazepril plus amlodipine or hydrochlorothiazide for hypertension.
    The New England journal of medicine, 2009, Mar-12, Volume: 360, Issue:11

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension

2009
Benazepril plus amlodipine or hydrochlorothiazide for hypertension.
    The New England journal of medicine, 2009, Mar-12, Volume: 360, Issue:11

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension

2009
Hypertension: an ACCOMPLISHED regimen for hypertension.
    Nature reviews. Nephrology, 2009, Volume: 5, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension

2009
Composite renal endpoints: was ACCOMPLISH accomplished?
    Lancet (London, England), 2010, Apr-03, Volume: 375, Issue:9721

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Calcium Channel Blockers; Creatinine; Disease Progression; Diuretics; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Kidney Failure, Chronic; Renin-Angiotensin System

2010
Medication nonadherence due to misunderstanding of the salt form.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:1

    Topics: Antihypertensive Agents; Benzazepines; Drug Labeling; Humans; Hydrochlorothiazide; Losartan; Medication Adherence; Medication Errors; Patient Education as Topic; Salts; Terminology as Topic

2014
Simultaneous determination of hydrochlorothiazide and benazepril hydrochloride or amiloride hydrochloride in presence of hydrochlorothiazide impurities: chlorothiazide and salamide by HPTLC method.
    Journal of chromatographic science, 2015, Volume: 53, Issue:1

    Topics: Amiloride; Benzazepines; Chlorothiazide; Chromatography, High Pressure Liquid; Drug Contamination; Hydrochlorothiazide

2015
Linear support vector regression and partial least squares chemometric models for determination of Hydrochlorothiazide and Benazepril hydrochloride in presence of related impurities: a comparative study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Sep-15, Volume: 130

    Topics: Algorithms; Benzazepines; Calibration; Chemistry, Pharmaceutical; Chlorothiazide; Chromatography, High Pressure Liquid; Drug Combinations; Drug Contamination; Hydrochlorothiazide; Least-Squares Analysis; Linear Models; Multivariate Analysis; Reproducibility of Results; Software; Spectrophotometry, Ultraviolet; Tablets

2014
Prior Medications and the Cardiovascular Benefits From Combination Angiotensin-Converting Enzyme Inhibition Plus Calcium Channel Blockade Among High-Risk Hypertensive Patients.
    Journal of the American Heart Association, 2018, 01-04, Volume: 7, Issue:1

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cause of Death; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Sodium Chloride Symporter Inhibitors; Time Factors; Treatment Outcome

2018
Simultaneous ultraperformance liquid chromatography/tandem mass spectrometry determination of four antihypertensive drugs in human plasma using hydrophilic-lipophilic balanced reversed-phase sorbents sample preparation protocol.
    Biomedical chromatography : BMC, 2018, Volume: 32, Issue:12

    Topics: Antihypertensive Agents; Benzazepines; Captopril; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Fosinopril; Humans; Hydrochlorothiazide; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Linear Models; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry

2018
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:9

    Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan

2019