hydrochlorothiazide has been researched along with avapro in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (5.41) | 18.2507 |
| 2000's | 55 (49.55) | 29.6817 |
| 2010's | 43 (38.74) | 24.3611 |
| 2020's | 7 (6.31) | 2.80 |
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Man in't Veld, AJ | 1 |
| Guthrie, RM; Kassler-Taub, KB; Littlejohn, TW; Pool, JL; Raskin, P; Reeves, RA; Shephard, AM; Weber, MA; Weir, MR; Wilson, TW; Wright, J | 1 |
| Lin, CS; MacNeil, D; Osbakken, M; Rosenstock, J; Rossi, L | 1 |
| Guthrie, R; Kassler-Taub, K; Kochar, M; Reeves, RA; Triscari, J | 1 |
| Flack, J; Guthrie, R; Raskin, P; Reeves, R; Saini, R | 1 |
| Howe, P; Kassler-Taub, K; Phillips, P; Saini, R | 1 |
| Park, JB; Pu, Q; Schiffrin, EL | 1 |
| Albero, I; García, S; Ródenas, V; Sánchez-Pedreño, C | 1 |
| Dao, HH; De Champlain, J; Essalihi, R; Graillon, JF; Larivière, R; Moreau, P | 1 |
| Bassett, ML; Fisher, AA | 1 |
| Erk, N | 2 |
| Angulo, E; Barquero, A; Grois, J; Pérez Miranda, M; Robles, NR | 1 |
| Aranda, P; Calvo, C; Coca, A; de la Sierra, A; Luque, M; Marín-Iranzo, R; Ruilope, LM | 1 |
| Preobrazhenskiĭ, DV; Sidorenko, BA; Stetsenko, TM; Tarykina, EV; Tsurko, VV | 1 |
| Bragulat, E; Calvo, C; Coca, A; de la Sierra, A; Gómez, E; López-Paz, JE; Sierra, C; Sobrino, J | 1 |
| Corradi, L; Derosa, G; Fogari, E; Fogari, R; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Beattie, E; Dominiczak, AF; Graham, D; Hamilton, C; Spiers, A | 1 |
| Caccese, D; Germanò, G; Lauro, R; Lenti, L; Pignatelli, P; Ragazzo, M; Sanguigni, V; Violi, F | 1 |
| Burnier, M; Ferrari, P; Hess, L; Muggli, F; Pechere-Bertschi, A | 1 |
| Bramlage, P; Kirch, W; Pittrow, D | 1 |
| Bramlage, P; Kirch, W; Lehnert, H; Pittrow, D | 1 |
| Carlucci, G; Giannandrea, A; Mazzeo, P; Vetuschi, C | 1 |
| Bramlage, P; Kirch, W; Sharma, AM | 2 |
| Chen, J; Jing, S; Sun, NL | 1 |
| Krekler, M; Schmieder, RE | 2 |
| Bakris, GL; Cushman, WC; Ferdinand, KC; Neutel, JM; Ofili, EO; Saunders, E; Sowers, JR; Weber, MA | 3 |
| Asmar, R; Bobrie, G; Delonca, J; Giacomino, A; Moulin, C; Postel-Vinay, N | 1 |
| Huang, XH; Li, J; Qiu, FR; Xie, HT | 1 |
| Athanasiadis, GI; Kollmar, A; Ollert, M; Pfab, F; Ring, J | 1 |
| Jiang, YY; Shen, FM; Su, DF; Xie, HH; Zhang, XF | 1 |
| Tschöpe, C; Tschöpe, R; Unger, T | 1 |
| Barton, J; Dicker, P; Jensen, C; Mulcahy, D; Nussberger, J; O'Brien, E; Stanton, A | 1 |
| Bhaumik, A; Franklin, SS; Lapuerta, P; Neutel, JM; Oparil, S; Ptaszynska, A | 1 |
| Boye, SW; Engeli, S; Jordan, J; Keefe, DL; Le Breton, S | 1 |
| Bramlage, P; Kintscher, U; Paar, WD; Thoenes, M; Unger, T | 1 |
| Gao, S; Guo, Q; Liu, F; Xu, Y; Zhang, J | 1 |
| Bramlage, P; Lüders, S; Paar, DW; Schirmer, A; Schrader, J; Thoenes, M | 1 |
| Coca, A; Ferreira-Melo, SE; Moreno, H; Nogueira, EA; Souza, LA; Ubaid-Girioli, S; Yugar-Toledo, JC | 1 |
| Bhaumik, A; Franklin, SS; Lapuerta, P; Neutel, JM; Ptaszynska, A | 1 |
| Krekler, M; Münzel, F; Parhofer, KG | 1 |
| Cox, D; Donovan, M; Franklin, S; Lapuerta, P | 1 |
| Bhaumik, A; De Obaldia, ME; Lapuerta, P; Neutel, JM; Weir, MR | 1 |
| Cable, G; Neutel, J; Saunders, E | 1 |
| Croxtall, JD; Keating, GM | 1 |
| Bienfait-Beuzon, C; Ekman, M; Jackson, J | 1 |
| Ali, SS; Arayne, MS; Sajid, S; Sultana, N | 1 |
| Lewin, AJ; Weir, MR | 1 |
| Cicero, AF; Derosa, G; Ferrari, I | 1 |
| Chrysant, SG; Ferdinand, KC; Neutel, JM | 1 |
| Bramlage, P | 1 |
| Franklin, S; Lapuerta, P | 1 |
| Fernández-Nieto, M; Heili, S; Manso, L; Sastre, B; Sastre, J | 1 |
| Bhaumik, A; Franklin, SS; Lapuerta, P; Neutel, JM; Oparil, S | 1 |
| Bramlage, P; Schmieder, RE; Schwertfeger, M | 1 |
| Alzoubi, MI; Arida, AI; Khabbas, MH; Tutunji, LF; Tutunji, MF | 1 |
| Savvatis, K; Schultheiss, HP; Tschöpe, C; Westermann, D | 1 |
| Burnier, M; Coltamai, L; Maillard, M; Simon, A; Vogt, B | 1 |
| Ekman, M; Fragoulakis, V; Maniadakis, N; Papagiannopoulou, V; Yfantopoulos, J | 1 |
| Franklin, SS; Neutel, JM | 1 |
| Patil, KR; Rane, VP; Sangshetti, JN; Shinde, DB; Yeole, RD | 1 |
| Asmar, R; Oparil, S | 1 |
| Harahap, Y; Lusthom, W; Meliala, RS; Prasaja, B; Sasongko, L; Setiawan, EC | 1 |
| Bamias, A; Constantinidis, C; Deliveliotis, C; Dimopoulos, MA; Karadimou, A; Lainakis, G; Manios, E; Michas, F; Zakopoulos, N | 1 |
| Circelli, M; Cremonesi, G; Fogari, R; Mugellini, A | 1 |
| Neutel, JM | 1 |
| Dall'Armi, V; Fini, M; Iellamo, F; Marazzi, G; Spoletini, I; Vitale, C; Volterrani, M | 1 |
| Celik, T; Yilmaz, MI | 1 |
| Brborić, J; Mulavdić, N; Smajić, M; Stankovic, P; Vujić, Z | 1 |
| Al Balushi, KA; Al-Zakwani, I; Habib, JQ | 1 |
| Malishevskiĭ, MV | 1 |
| Dai, QY; Huang, QF; Li, Y; Ma, GS; Sheng, CS; Wang, JG | 1 |
| Cabré, F; Cánovas, M; Polonio, F | 1 |
| Crull, G; Grosso, J; Pan, D; Yin, S | 1 |
| Agabiti-Rosei, E; Manolis, A; Omboni, S; Zava, D | 1 |
| Pan, X; Qiu, X; Wang, B; Wang, Z; Xu, RA; Zhan, H | 1 |
| Arli, G; Atkosar, Z; Can, NO; Koyuturk, S | 1 |
| Fayez, YM | 1 |
| Abdelhameed, AS; Alanazi, AM; Darwish, IA; Khalil, NY; Khan, AA | 1 |
| Özcan, EE; Özel, E; Öztürk, A; Senaslan, Ö; Uyar, S | 1 |
| Hedaya, MA; Helmy, SA | 1 |
| Abdel Monem Hegazy, M; Fayez, YM | 1 |
| Hu, X; Liu, J; ShenTu, J; Wu, G; Wu, L; Zhai, Y; Zheng, Y; Zhou, H; Zhu, M | 1 |
| Deng, SB; Du, JL; Liu, YJ; Qiu, B; She, Q; Wang, J | 1 |
| Arca, M; Berra, S; Bucci, M; Calabrò, P; Fulgheri, PL; Ghione, S; Modesti, PA; Omboni, S; Pirvu, O; Popescu, E; Portaluppi, F; Pozzilli, P; Taddei, S; Velican, VG; Villani, GQ; Vladoianu, M; Volpe, M | 1 |
| Argyropoulou, MI; Christopoulou, F; Elisaf, M; Kosta, P; Rizos, EC | 1 |
| Borghi, C; Napoli, C; Omboni, S | 1 |
| Azizi, M; Bergerot, D; Blanchard, A; Bobrie, G; Courand, PY; Dubourg, J; Forni, V; Frank, M; Menard, J; Mendes, M | 1 |
| Brambilla, G; Dell'Oro, R; Fici, F; Grassi, G; Mancia, G; Seravalle, G; Trevano, FQ; van Bortel, L | 1 |
| Chadha, R; Haneef, J | 1 |
| Atkins, E; Bennett, A; Burke, M; Chalmers, J; Chou, M; Chow, CK; Dehbi, HM; Hillis, G; Hilmer, S; Krum, H; Neal, B; Nelson, M; Patel, A; Peiris, D; Reid, CM; Rodgers, A; Rogers, K; Salam, A; Thakkar, J; Thom, S; Usherwood, T; Vo, K; Webster, R; Woodward, M | 1 |
| Agabiti-Rosei, E; Borghi, C; Malacco, E; Manolis, A; Modesti, PA; Napoli, C; Omboni, S; Parati, G | 1 |
| Burnier, M; Noll, G; Noll, S; Rimoldi, S; Spirk, D; Sudano, I | 1 |
| Abdelsalam, RA; Haddad, GM; Marghany, KA | 1 |
| Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM | 1 |
| Huang, QF; Li, Y; Wang, JG; Zhang, D | 1 |
| Huang, QF; Li, Y; Wang, JG; Ye, XF | 1 |
| Chen, J; Dong, G; Ge, M; Liu, H; Luo, Y; Wang, J; Yan, P; Zhang, J | 1 |
| Liang, H; Tang, T; Xie, M | 1 |
13 review(s) available for hydrochlorothiazide and avapro
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical overview of irbesartan: expanding the therapeutic window in hypertension.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Controlled Clinical Trials as Topic; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Safety; Tetrazoles | 1997 |
Acute pancreatitis associated with angiotensin II receptor antagonists.
Topics: Acute Disease; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Irbesartan; Losartan; Pancreatitis; Sodium Chloride Symporter Inhibitors; Tetrazoles | 2002 |
[Angiotensin I receptor antagonist losartan. Part II. Effects in arterial hypertension and diabetic nephropathy].
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Meta-Analysis as Topic; Placebos; Prognosis; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2003 |
Irbesartan and hydrochlorothiazide association in the treatment of hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Tetrazoles | 2009 |
Fixed combination of irbesartan and hydrochlorothiazide in the management of hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Tetrazoles; Treatment Outcome | 2009 |
The risks and benefits of initial irbesartan/hydrochlorothiazide combination therapy in patients with severe hypertension.
Topics: Antihypertensive Agents; Biphenyl Compounds; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Risk Assessment; Severity of Illness Index; Tetrazoles | 2009 |
Rational of the use of aliskiren in hypertension and beyond.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Europe; Fumarates; Germany; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Japan; Prevalence; Prorenin Receptor; Protein Precursors; Randomized Controlled Trials as Topic; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; World Health Organization | 2009 |
Combination delapril/manidipine as antihypertensive therapy in high-risk patients.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Dihydropyridines; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Irbesartan; Losartan; Nitrobenzenes; Obesity; Olmesartan Medoxomil; Piperazines; Ramipril; Tetrazoles; Valine; Valsartan | 2011 |
[Irbesartan in clinical practice].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Monitoring; Drug Synergism; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Irbesartan; Patient Compliance; Patient Preference; Renin-Angiotensin System; Tetrazoles; Treatment Outcome | 2012 |
Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review.
Topics: Administration, Oral; Amlodipine; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome | 2017 |
Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized "Z" Studies.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Glucose; Blood Pressure; C-Reactive Protein; Captopril; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Inflammation Mediators; Irbesartan; Lipids; Male; Middle Aged; Pulse Wave Analysis; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Vascular Stiffness | 2017 |
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan | 2023 |
51 trial(s) available for hydrochlorothiazide and avapro
| Article | Year |
|---|---|
Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Treatment Outcome | 1998 |
The effects of irbesartan added to hydrochlorothiazide for the treatment of hypertension in patients non-responsive to hydrochlorothiazide alone.
Topics: Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Demography; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Single-Blind Method; Tetrazoles; Treatment Outcome | 1998 |
Matrix study of irbesartan with hydrochlorothiazide in mild-to-moderate hypertension.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Potassium; Sample Size; Single-Blind Method; Sodium Chloride Symporter Inhibitors; Tetrazoles; Uric Acid | 1999 |
The long-term antihypertensive activity and tolerability of irbesartan with hydrochlorothiazide.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Double-Blind Method; Drug Hypersensitivity; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Lipids; Male; Middle Aged; Safety; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Treatment Outcome | 1999 |
The antihypertensive efficacy of the combination of irbesartan and hydrochlorothiazide assessed by 24-hour ambulatory blood pressure monitoring. Irbesartan Multicenter Study Group.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reproducibility of Results; Safety; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome | 1999 |
Effect of crossing over hypertensive patients from a beta-blocker to an angiotensin receptor antagonist on resistance artery structure and on endothelial function.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arteries; Atenolol; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Echocardiography; Endothelium, Vascular; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Irbesartan; Male; Middle Aged; Nitroprusside; Receptors, Angiotensin; Sensitivity and Specificity; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Vascular Resistance | 2002 |
[Comparison of the antihypertensive activity of fosinopril and irbesartan].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Therapy, Combination; Female; Fosinopril; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles; Treatment Outcome | 2002 |
[Effect of anti-hypertensive therapy with irbesartan on the absolute cardiovascular risk].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Risk Assessment; Risk Factors; Tetrazoles; Treatment Outcome | 2003 |
Once-daily fixed-combination irbesartan 300 mg/ hydrochlorothiazide 25 mg and circadian blood pressure profile in patients with essential hypertension.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles | 2003 |
Effect of delapril-manidipine combination vs irbesartan-hydrochlorothiazide combination on fibrinolytic function in hypertensive patients with type II diabetes mellitus.
Topics: Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Fibrinolysis; Humans; Hydrochlorothiazide; Hypertension; Indans; Irbesartan; Male; Middle Aged; Nitrobenzenes; Piperazines; Plasminogen Activator Inhibitor 1; Tetrazoles; Tissue Plasminogen Activator; Treatment Outcome | 2004 |
Enhanced platelet release of superoxide anion in systemic hypertension: role of AT1 receptors.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Platelets; Case-Control Studies; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; NADPH Oxidases; Receptor, Angiotensin, Type 1; Sodium Chloride Symporter Inhibitors; Superoxides; Tetrazoles | 2004 |
Reasons for not intensifying antihypertensive treatment (RIAT): a primary care antihypertensive intervention study.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Female; Guideline Adherence; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Primary Health Care; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome | 2004 |
The effect of irbesartan in reducing cardiovascular risk in hypertensive type 2 diabetic patients: an observational study in 16,600 patients in primary care.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Primary Health Care; Prospective Studies; Risk Factors; Tetrazoles | 2004 |
[IRMA-pRAcs: irbesartan in the treatment of microalbuminuria and proteinuria in patients with type 2 diabetes and hypertension-prospective observational study involving 38,016 patients in the general practice setting].
Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Primary Health Care; Prospective Studies; Proteinuria; Receptor, Angiotensin, Type 1; Tetrazoles | 2003 |
[The control rate of irbesartan/hydrochlorothiazide combination regimen in the treatment of Chinese patients with mild to moderate hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; China; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Middle Aged; Tablets; Tetrazoles; Young Adult | 2005 |
The efficacy and safety of low- and high-dose fixed combinations of irbesartan/hydrochlorothiazide in patients with uncontrolled systolic blood pressure on monotherapy: the INCLUSIVE trial.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2005 |
[Observational study of blood pressure control and microalbuminuria in type 2 diabetics on irbesartan or irbesartan/HCTZ].
Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2005 |
A home blood pressure monitoring study comparing the antihypertensive efficacy of two angiotensin II receptor antagonist fixed combinations.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Musculoskeletal Diseases; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Irbesartan/HCTZ fixed combinations in patients of different racial/ethnic groups with uncontrolled systolic blood pressure on monotherapy.
Topics: Antihypertensive Agents; Biphenyl Compounds; Black People; Blood Pressure; Drug Combinations; Female; Hispanic or Latino; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Prospective Studies; Single-Blind Method; Tetrazoles; White People | 2006 |
[Arterial hypertension in obese patients. Rationale for a prospective medical care study in the family doctor's practice].
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Causality; Clinical Trials as Topic; Combined Modality Therapy; Comorbidity; Coronary Disease; Diabetes Mellitus, Type 2; Diet, Reducing; Dose-Response Relationship, Drug; Drug Combinations; Family Practice; Germany; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Obesity; Prospective Studies; Proteinuria; Tetrazoles | 2004 |
Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker.
Topics: Adult; Aged; Aged, 80 and over; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Patient Compliance; Ramipril; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles | 2007 |
Efficacy and safety of irbesartan/HCTZ combination therapy as initial treatment for rapid control of severe hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Tetrazoles; Treatment Outcome; United States | 2006 |
Direct Renin inhibition with aliskiren in obese patients with arterial hypertension.
Topics: Administration, Oral; Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diastole; Double-Blind Method; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Obesity; Renin; Systole; Tetrazoles; Treatment Outcome | 2007 |
Aldosterone escape with diuretic or angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy in patients with mild to moderate hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Quinapril; Tetrahydroisoquinolines; Tetrazoles | 2007 |
A comparison of the efficacy and safety of irbesartan/HCTZ combination therapy with irbesartan and HCTZ monotherapy in the treatment of moderate hypertension.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2008 |
Effect of the angiotensin receptor blocker irbesartan on metabolic parameters in clinical practice: the DO-IT prospective observational study.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diastole; Drug Therapy, Combination; Family Practice; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Metabolic Syndrome; Prospective Studies; Systole; Tetrazoles; Weight Loss | 2007 |
Initial combination therapy with irbesartan/hydrochlorothiazide for hypertension: an analysis of the relationship between baseline blood pressure and the need for combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Time Factors | 2007 |
The efficacy and safety of initial use of irbesartan/hydrochlorothiazide fixed-dose combination in hypertensive patients with and without high cardiovascular risk.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Obesity; Risk Factors; Tetrazoles; Treatment Outcome | 2007 |
Predictors of blood pressure response to angiotensin receptor blocker/diuretic combination therapy: a secondary analysis of the irbesartan/hydrochlorothiazide blood pressure reductions in diverse patient populations (INCLUSIVE) study.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Systole; Tetrazoles | 2008 |
Antihypertensive efficacy and tolerability of irbesartan/hydrochlorothiazide in hypertensive patients stratified by body mass index and type 2 diabetes mellitus status: a post hoc subgroup analysis of the Irbesartan/HCTZ Blood Pressure Reductions in Diver
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Body Mass Index; Body Weight; Cluster Analysis; Diabetes Mellitus, Type 2; Dizziness; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Irbesartan; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome | 2008 |
Irbesartan/hydrochlorothiazide for the treatment of isolated systolic hypertension: a subgroup analysis of the INCLUSIVE trial.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Confidence Intervals; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Irbesartan; Male; Middle Aged; Prospective Studies; Risk Factors; Tetrazoles | 2009 |
Safety and tolerability of fixed-dose irbesartan/hydrochlorothiazide for rapid control of severe hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Sodium Chloride Symporter Inhibitors; Tetrazoles; Young Adult | 2009 |
Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma using HPLC coupled with tandem mass spectrometry: Application to bioequivalence studies.
Topics: Administration, Oral; Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Calibration; Chemical Precipitation; Chromatography, High Pressure Liquid; Cross-Over Studies; Diuretics; Drug Combinations; Drug Stability; Humans; Hydrochlorothiazide; Irbesartan; Male; Middle Aged; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Tetrazoles; Therapeutic Equivalency; Young Adult | 2010 |
Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a thiazide diuretic in humans.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Imidazoles; Irbesartan; Kidney Tubules; Losartan; Single-Blind Method; Tetrazoles; Valine; Valsartan | 2010 |
Efficacy and safety of irbesartan/HCTZ in severe hypertension according to cardiometabolic factors.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Body Mass Index; Confidence Intervals; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Obesity; Risk Factors; Systole; Tetrazoles | 2010 |
Comparison of the antihypertensive efficacy of irbesartan/HCTZ and valsartan/HCTZ combination therapy: impact of age and gender.
Topics: Adolescent; Adult; Age Factors; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Sex Characteristics; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Comparative bioavailability of two irbesartan/hydrochlorothiazide tablet formulations in Indonesian healthy subjects.
Topics: Adolescent; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Area Under Curve; Biological Availability; Biphenyl Compounds; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Indonesia; Irbesartan; Male; Mass Spectrometry; Tetrazoles; Therapeutic Equivalency; Young Adult | 2010 |
A comparison of the efficacy and safety of irbesartan/hydrochlorothiazide combination therapy with irbesartan monotherapy in the treatment of moderate or severe hypertension in diabetic and obese hypertensive patients: a post-hoc analysis review.
Topics: Antihypertensive Agents; Biphenyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome | 2011 |
Effects of nebivolol or irbesartan in combination with hydrochlorothiazide on vascular functions in newly-diagnosed hypertensive patients: the NINFE (Nebivololo, Irbesartan Nella Funzione Endoteliale) study.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Benzopyrans; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Diuretics; Drug Therapy, Combination; Endothelium, Vascular; Ethanolamines; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Nebivolol; Pulsatile Flow; Tetrazoles; Treatment Outcome; Vascular Stiffness | 2012 |
Efficacy and safety of a fixed combination of irbesartan/hydrochlorothiazide in Chinese patients with moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Albuminuria; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Irbesartan; Male; Middle Aged; Tetrazoles | 2013 |
Bioequivalence studies for 2 different strengths of irbesartan/hydrochlorothiazide combination in healthy volunteers: 300/25 mg and 300/12.5 mg film-coated tablets.
Topics: Adult; Area Under Curve; Biphenyl Compounds; Cross-Over Studies; Drug Combinations; Female; Healthy Volunteers; Humans; Hydrochlorothiazide; Irbesartan; Male; Tablets; Tetrazoles; Therapeutic Equivalency | 2014 |
Zofenopril plus hydrochlorothiazide and irbesartan plus hydrochlorothiazide in previously treated and uncontrolled diabetic and non-diabetic essential hypertensive patients.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Captopril; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Young Adult | 2014 |
Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma by ultra high performance liquid chromatography tandem mass spectrometry and its application to a bioequivalence study.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Hydrochlorothiazide; Irbesartan; Linear Models; Male; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tetrazoles; Therapeutic Equivalency | 2014 |
Modeling of the pharmacokinetic/pharmacodynamic interaction between irbesartan and hydrochlorothiazide in normotensive subjects.
Topics: Adolescent; Adult; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Heart Rate; Humans; Hydrochlorothiazide; Irbesartan; Male; Models, Biological; Tetrazoles; Young Adult | 2015 |
Pharmacokinetic properties and bioequivalence of two irbesartan/ hydrochlorothiazide fixed-dose combination tablets in healthy male Chinese volunteers.
Topics: Administration, Oral; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Area Under Curve; Asian People; Biphenyl Compounds; China; Chromatography, High Pressure Liquid; Cross-Over Studies; Diuretics; Drug Combinations; Drugs, Generic; Healthy Volunteers; Humans; Hydrochlorothiazide; Irbesartan; Male; Metabolic Clearance Rate; Tablets; Tandem Mass Spectrometry; Tetrazoles; Therapeutic Equivalency; Young Adult | 2015 |
The effects of a low-salt diet on the efficacy of different antihypertensive drug regimens.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Drug Synergism; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Tetrazoles; Young Adult | 2015 |
Zofenopril or irbesartan plus hydrochlorothiazide in elderly patients with isolated systolic hypertension untreated or uncontrolled by previous treatment: a double-blind, randomized study.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Systole; Tetrazoles; Treatment Outcome; Vascular Stiffness | 2016 |
Fixed-dose combination of zofenopril plus hydrochlorothiazide vs. irbesartan plus hydrochlorothiazide in hypertensive patients with established metabolic syndrome uncontrolled by previous monotherapy. The ZAMES study (Zofenopril in Advanced MEtabolic Synd
Topics: Aged; Biphenyl Compounds; Captopril; Female; Humans; Hydrochlorothiazide; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Tetrazoles | 2016 |
Multicenter Randomized Double-Blind Comparison of Nebivolol plus HCTZ and Irbesartan plus HCTZ in the Treatment of Isolated Systolic Hypertension in Elderly Patients: Results of the NEHIS Study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Belgium; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Nebivolol; Netherlands; Tetrazoles | 2017 |
Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review.
Topics: Administration, Oral; Amlodipine; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome | 2017 |
Effect of administration of low-dose irbesartan and hydrochlorothiazide combined with levamlodipine at different times on the circadian rhythm of blood pressure and the levels of MMPs and TIMPs in non-dipper patients with grade 1 and 2 hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Irbesartan; Prospective Studies | 2023 |
48 other study(ies) available for hydrochlorothiazide and avapro
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Determination of irbesartan in the presence of hydrochlorothiazide by derivative spectrophotometry.
Topics: Antihypertensive Agents; Biphenyl Compounds; Drug Interactions; Hydrochlorothiazide; Irbesartan; Spectrophotometry; Tablets; Tetrazoles | 2002 |
Pharmacological prevention and regression of arterial remodeling in a rat model of isolated systolic hypertension.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Arteries; Biphenyl Compounds; Calcinosis; Collagen; Disease Models, Animal; Elastin; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Cerebral Artery; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Tetrazoles | 2002 |
Simultaneous determination of irbesartan and hydrochlorothiazide in human plasma by liquid chromatography.
Topics: Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Diuretics; Humans; Hydrochlorothiazide; Irbesartan; Reproducibility of Results; Sensitivity and Specificity; Sodium Chloride Symporter Inhibitors; Spectrophotometry, Ultraviolet; Tetrazoles | 2003 |
Three new spectrophotometric methods applied to the simultaneous determination of hydrochlorothiazide and irbesartan.
Topics: Antihypertensive Agents; Biphenyl Compounds; Calibration; Drug Combinations; Hydrochlorothiazide; Indicators and Reagents; Irbesartan; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles | 2003 |
Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences.
Topics: Animals; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Blood Pressure; Carbachol; Cardiomegaly; Carotid Arteries; Drug Synergism; Echocardiography; Endothelium, Vascular; Female; Hormones; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Nitric Oxide; Pyridines; Rats; Rats, Inbred SHR; Sex Characteristics; Stroke; Systole; Tetrazoles; Thiazepines; Vasodilation | 2004 |
Determination of hydrochlorothiazide and irbesartan in pharmaceuticals by fourth-order UV derivative spectrophotometry.
Topics: Biphenyl Compounds; Hydrochlorothiazide; Irbesartan; Molecular Structure; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet; Tetrazoles | 2005 |
[Good blood pressure control even in overweight patients].
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Middle Aged; Obesity; Tetrazoles; Treatment Outcome | 2005 |
[Observational study of blood pressure control and microalbuminuria in type 2 diabetics on Irbesartan or Irbesartan/HCTZ].
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Multicenter Studies as Topic; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors | 2005 |
Pharmacokinetic and pharmacodynamic interaction between irbesartan and hydrochlorothiazide in renal hypertensive dogs.
Topics: Animals; Biphenyl Compounds; Dogs; Drug Interactions; Drug Therapy, Combination; Hydrochlorothiazide; Hypertension, Renal; Irbesartan; Models, Biological; Tetrazoles | 2005 |
Lichenoid drug eruption due to an antihypertonic drug containing irbesartan and hydrochlorothiazide.
Topics: Aged; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Drug Eruptions; Female; Humans; Hydrochlorothiazide; Irbesartan; Lichenoid Eruptions; Tetrazoles | 2006 |
Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Aorta; Atenolol; Baroreflex; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Irbesartan; Kidney Diseases; Male; Nifedipine; Rats; Rats, Inbred SHR; Tetrazoles | 2006 |
Antihypertensive efficacy of Irbesartan/HCTZ in men and women with the metabolic syndrome and type 2 diabetes.
Topics: Adult; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Sex Factors; Tetrazoles; Treatment Outcome; United States | 2006 |
[Microalbuminuria in patients with hypertension and cardiovascular comorbidity, REAL observational study of treatment with Irbesartan/HCTZ].
Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Kidney Diseases; Risk Factors; Tetrazoles; Time Factors | 2006 |
Irbesartan for the treatment of hypertension in patients with the metabolic syndrome: a sub analysis of the Treat to Target post authorization survey. Prospective observational, two armed study in 14,200 patients.
Topics: Abdominal Fat; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cholesterol, HDL; Cohort Studies; Drug Therapy, Combination; Fasting; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Risk Factors; Tetrazoles; Triglycerides | 2007 |
Determination of hydrochlorothiazide in human plasma by liquid chromatography/tandem mass spectrometry.
Topics: Administration, Oral; Antihypertensive Agents; Biphenyl Compounds; Chromatography, Liquid; Diuretics; Drug Stability; Freezing; Humans; Hydrochlorothiazide; Irbesartan; Methanol; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solvents; Tablets; Tandem Mass Spectrometry; Temperature; Tetrazoles; Time Factors; Water | 2007 |
[Successful high dosage fixed combination. 7 of 10 patients achieve target blood pressure].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Tetrazoles | 2006 |
BP goal achievement in patients with uncontrolled hypertension : results of the treat-to-target post-marketing survey with irbesartan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Patient Compliance; Product Surveillance, Postmarketing; Prospective Studies; Tetrazoles | 2007 |
Irbesartan/Hydrochlorothiazide : in moderate to severe hypertension.
Topics: Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Severity of Illness Index; Tetrazoles | 2008 |
Cost-effectiveness of irbesartan/hydrochlorothiazide in patients with hypertension: an economic evaluation for Sweden.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Health Services; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Patents as Topic; Quality-Adjusted Life Years; Risk Factors; Sensitivity and Specificity; Sweden; Tetrazoles; Young Adult | 2008 |
Simultaneous determination of olmesartan medoxomil and irbesartan and hydrochlorothiazide in pharmaceutical formulations and human serum using high performance liquid chromatography.
Topics: Biphenyl Compounds; Blood Chemical Analysis; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Imidazoles; Irbesartan; Olmesartan Medoxomil; Pharmaceutical Preparations; Reproducibility of Results; Tetrazoles; Time Factors | 2008 |
Basophil activation in two cases of hydrochlorothiazide-induced noncardiogenic pulmonary edema.
Topics: Aged; Amiloride; Antihypertensive Agents; Basophils; Biphenyl Compounds; Diuretics; Female; Humans; Hydrochlorothiazide; Irbesartan; Male; Middle Aged; Pulmonary Edema; Tetrazoles | 2010 |
Significance of initial blood pressure and comorbidity for the efficacy of a fixed combination of an angiotensin receptor blocker and hydrochlorothiazide in clinical practice.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Comorbidity; Diuretics; Drug Combinations; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Medication Adherence; Middle Aged; Primary Health Care; Tetrazoles; Time Factors; Treatment Outcome | 2009 |
Economic evaluation of irbesartan in combination with hydrochlorothiazide in the treatment of hypertension in Greece.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Combinations; Female; Greece; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Male; Markov Chains; Middle Aged; Models, Economic; Quality of Life; Sex Factors; Tetrazoles; Valine; Valsartan | 2011 |
Stability indicating LC method for simultaneous determination of irbesartan and hydrochlorothiazide in pharmaceutical preparations.
Topics: Biphenyl Compounds; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Hydrochlorothiazide; Irbesartan; Linear Models; Parabens; Reproducibility of Results; Sensitivity and Specificity; Tetrazoles | 2010 |
The use of 24-h ambulatory blood pressure monitoring (ABPM) during the first cycle of sunitinib improves the diagnostic accuracy and management of hypertension in patients with advanced renal cancer.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Benzopyrans; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Carcinoma, Renal Cell; Ethanolamines; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Irbesartan; Male; Middle Aged; Nebivolol; Prevalence; Pyrroles; Reproducibility of Results; Sunitinib; Tetrazoles; Time Factors; Treatment Outcome | 2011 |
The beneficial effects of nebivolol on endothelial functions in arterial hypertension.
Topics: Benzopyrans; Biphenyl Compounds; Blood Pressure; Ethanolamines; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Nebivolol; Tetrazoles | 2012 |
Simultaneous analysis of irbesartan and hydrochlorothiazide: an improved HPLC method with the aid of a chemometric protocol.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Irbesartan; Molecular Structure; Tetrazoles | 2012 |
Comparative efficacy of irbesartan/ hydrochlorothiazide and valsartan/hydrochlorothiazide combination in lowering blood pressure: a retrospective observational study in Oman.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Oman; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2013 |
Low level drug product API form analysis - Avalide tablet NIR quantitative method development and robustness challenges.
Topics: Biphenyl Compounds; Chemistry, Pharmaceutical; Humidity; Hydrochlorothiazide; Irbesartan; Limit of Detection; Particle Size; Spectroscopy, Near-Infrared; Tablets; Tetrazoles | 2014 |
A novel dilute and shoot HPLC assay method for quantification of irbesartan and hydrochlorothiazide in combination tablets and urine using second generation C18-bonded monolithic silica column with double gradient elution.
Topics: Acetamides; Biphenyl Compounds; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Irbesartan; Limit of Detection; Reference Standards; Sensitivity and Specificity; Silicon Dioxide; Tablets; Tetrazoles | 2014 |
Simultaneous determination of some anti-hypertensive drugs in their binary mixture by novel spectrophotometric methods.
Topics: Analysis of Variance; Antihypertensive Agents; Biphenyl Compounds; Hydrochlorothiazide; Irbesartan; Powders; Regression Analysis; Spectrophotometry; Tablets; Tetrazoles | 2014 |
HPLC method with monolithic column for simultaneous determination of irbesartan and hydrochlorothiazide in tablets.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Irbesartan; Tablets; Tetrazoles | 2014 |
Medical treatment of an adult with uncorrected isolated interrupted aorta resulted in no complications after 4 years of follow-up.
Topics: Angiography; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Aorta, Thoracic; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Irbesartan; Middle Aged; Multidetector Computed Tomography; Tetrazoles; Time Factors; Vascular Malformations | 2014 |
Mean centering of ratio spectra and concentration augmented classical least squares in a comparative approach for quantitation of spectrally overlapped bands of antihypertensives in formulations.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hydrochlorothiazide; Irbesartan; Least-Squares Analysis; Spectrophotometry; Tablets; Tetrazoles | 2015 |
Does this patient have hypertensive encephalopathy?
Topics: Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Brain; Carbazoles; Carvedilol; Computed Tomography Angiography; Confusion; Creatinine; Electrocardiography; Glomerular Filtration Rate; Hallucinations; Headache; Heart; Humans; Hydrochlorothiazide; Hypertension; Hypertensive Encephalopathy; Irbesartan; Magnetic Resonance Imaging; Male; Middle Aged; Propanolamines; Renal Artery Obstruction; Spironolactone; Tetrazoles; Ultrasonography | 2016 |
Copeptin is increased in resistant hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Pressure; Coronary Vasospasm; Diuretics; Female; Glomerular Filtration Rate; Glycopeptides; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Nephrons; Osmolar Concentration; Renin-Angiotensin System; Sex Factors; Tetrazoles; Vasopressins | 2016 |
Drug-Drug Multicomponent Solid Forms: Cocrystal, Coamorphous and Eutectic of Three Poorly Soluble Antihypertensive Drugs Using Mechanochemical Approach.
Topics: Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biphenyl Compounds; Crystallization; Drug Combinations; Female; Hydrochlorothiazide; Irbesartan; Rats; Rats, Wistar; Solubility; Telmisartan; Tetrazoles | 2017 |
Effect of Home Blood Pressure Monitoring on Patient's Awareness and Goal Attainment Under Antihypertensive Therapy: The Factors Influencing Results in Anti-HypertenSive Treatment (FIRST) Study.
Topics: Aged; Antihypertensive Agents; Awareness; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Goals; Humans; Hydrochlorothiazide; Irbesartan; Male; Middle Aged; Self Care; Switzerland; Tetrazoles; Treatment Outcome | 2018 |
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers.
Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan | 2020 |
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan | 2020 |
Incident hyperuricemia in relation to antihypertensive therapy with the irbesartan/hydrochlorothiazide combination.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Humans; Hydrochlorothiazide; Hypertension; Hyperuricemia; Irbesartan; Tetrazoles; Uric Acid | 2021 |
Seasonal variation in the effect of antihypertensive treatment with the irbesartan/hydrochlorothiazide combination.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Seasons; Tetrazoles | 2023 |