hydrochlorothiazide and aliskiren

hydrochlorothiazide has been researched along with aliskiren in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	20 (35.09)	29.6817
2010's	37 (64.91)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bizot, MN; Denouel, J; Dieterich, HA; Dole, WP; Kemp, C; Vaidyanathan, S; Valencia, J; Yeh, CM; Zhao, C	1
Calhoun, D; Chrysant, SG; Hsu, H; Matrisciano-Dimichino, L; Schober, B; Villamil, A; Zhang, J	1
Barton, J; Dicker, P; Jensen, C; Mulcahy, D; Nussberger, J; O'Brien, E; Stanton, A	1
Aldigier, JC; Azizi, M; Chiang, Y; Januszewicz, A; Pool, JL; Satlin, A; Schmieder, RE; Zidek, W	1
Boye, SW; Engeli, S; Jordan, J; Keefe, DL; Le Breton, S	1
Ashiya, M; Smith, RE	1
Ali, MA; Andersen, K; Constance, CM; Egan, B; Jin, J; Keefe, DL; Weinberger, MH	1
Chrysant, SG; Dattani, D; Hoppe, UC; Hsu, H; Murray, AV; Patel, S; Zhang, J	1
Chrysant, SG	2
Botha, J; Gorostidi, M; Guerediaga, J; Maboudian, M; Philipp, T; Schmieder, RE; Smith, B; van Ingen, H; Weissbach, N	1
Bangalore, S; Messerli, FH	1
Lembo, G; Nickenig, G; Ritter, S; Rodriguez, P; Salko, T; Simanenkov, V; Zhang, J	1
Andersen, K; Blumenstein, M; Calderón, A; Ibram, G; Liu, Z; Romaszko, J; Zhang, J	1
Sureshkumar, KK	1
Baldwin, CM; Plosker, GL	1
Bush, C; Gorostidi, M; Guerediaga, J; Keefe, DL; Philipp, T; Schmieder, RE	1
Barranco, E; Geiger, H; Gorostidi, M; Taylor, A; Xiang, Z; Zhang, J; Zhang, X	1
Savvatis, K; Schultheiss, HP; Tschöpe, C; Westermann, D	1
Chrysant, SG; Dattani, D; Hoppe, UC; Murray, AV; Patel, S; Ritter, S; Zhang, J	1
Benduhn, H; Klebs, S; Schweizer, J; Ulmer, HJ	1
Aguirre Palacios, F; Baschiera, F; Bijarnia, M; Black, HR; Kribben, A; Laflamme, AK	1
Babazadeh, S; Basile, J; Botha, J; Lillestol, M; Weitzman, R; Yurkovic, C	1
Ferdinand, KC; Pool, J; Purkayastha, D; Townsend, R; Weitzman, R	1
Handler, J	1
Dole, WP; Jarugula, V; Papst, CC; Sabo, R; Yan, JH; Zhang, J	1
Oliveira, PR; Rolim, CM; Sangoi, MS; Steppe, M; Wrasse-Sangoi, M	1
Baek, I; Drummond, W; Keefe, DL; Ramos, E; Sirenko, YM	1
Gradman, AH; Keefe, DL; Kolloch, RE; Lederballe, O; Sica, D; Zhang, J	1
Huang, J; Matavelli, LC; Siragy, HM	1
Bhosekar, V; Forker, AD; Keefe, DL; Townsend, RR; Yadao, A	1
Jaimes, EA; Judd, E	1
Fang, H; Konis, G; Lacourcière, Y; Severin, T; Taddei, S; Zhang, J	1
Aguirre P, F; Alessi, T; Baschiera, F; Black, HR; Wright, M	1
Huan, Y; Townsend, R	1
Garcia-Puig, J; Koenig, W; Murray, AV; Patel, S; Uddin, A; Zhang, J	1
Echtay, A; Go, L; Gulzar, T; Haque, KM; Hristoskova, S; Kadwa, M; Maddury, SR; Pande, A	1
Asai, K; Kubota, Y; Mizuno, K; Takahashi, H; Yasutake, M	1
Benitez, FN; Cedenio, H; Giorgi, M; Jaramillo, N; Molina, N; Volman, S; Zilberman, J	1
Adams-Huet, B; Best, SA; Bivens, TB; Fu, Q; Jarvis, SS; Levine, BD; Okada, Y	1
Cao, C; Dong, X; Gao, D; Liu, Y; Niu, X; Song, A; Wei, J; Yan, R	1
Belal, F; El-Enany, N; Walash, M; Zayed, S	1
Agaliotis, GD; Andreadis, EA; Angelopoulos, ET; Kolyvas, GN; Mousoulis, CG; Mousoulis, GP	1
Belal, F; Ebeid, WM; El-Enany, N; Patonay, G; Salim, MM; Walash, M	1
Bosch, J; Copland, I; Dagenais, G; Dans, A; Diaz, R; Joseph, P; Jung, H; Liu, L; Mancia, G; O'Donnell, M; Pfeffer, M; Pogue, J; Teo, KK; Yusuf, S	1
Mannemala, SS; Nagarajan, JS	1
Dimitriadis, GD; Ikonomidis, I; Kotsifaki, EE; Lambadiari, VA; Lekakis, JP; Maratou, EP; Markakis, KP; Mazioti, MC; Raptis, AE; Raptis, SA; Tsirogianni, AG; Vlahakos, DV; Voumvourakis, AN	1
Ebeid, WM; El-Bagary, RI; El-Zaher, AA; Elkady, EF; Patonay, G	1
El-Zeany, BA; Elzanfaly, ES; Hassan, SA; Salem, MY	2
Burnier, M; Forni, V; Hoffman, L; Maillard, M; Milani, B; Muller, ME; Piskunowicz, M; Pruijm, M; Vakilzadeh, N; Zweiacker, C	1
Ahmed, MS; El-Zaher, AA; Mahrouse, MA; Moussa, BA	1

Reviews

9 review(s) available for hydrochlorothiazide and aliskiren

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Aliskiren-hydrochlorothiazide combination for the treatment of hypertension. Expert review of cardiovascular therapy, 2008, Volume: 6, Issue:3 Topics: Amides; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Approval; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Randomized Controlled Trials as Topic; Renin; Risk Assessment; Severity of Illness Index; Survival Rate; Treatment Outcome; United States; United States Food and Drug Administration	2008
Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy. Vascular health and risk management, 2008, Volume: 4, Issue:6 Topics: Amides; Animals; Antihypertensive Agents; Drug Therapy, Combination; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Renin; Renin-Angiotensin System; Treatment Outcome	2008
Rational of the use of aliskiren in hypertension and beyond. Minerva cardioangiologica, 2009, Volume: 57, Issue:6 Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Europe; Fumarates; Germany; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Japan; Prevalence; Prorenin Receptor; Protein Precursors; Randomized Controlled Trials as Topic; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; World Health Organization	2009
In brief: Another three-drug combination for hypertension. The Medical letter on drugs and therapeutics, 2011, Apr-04, Volume: 53, Issue:1361 Topics: Amides; Amlodipine; Animals; Drug Approval; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Tablets; United States	2011
Single-pill triple-combination therapy: an alternative to multiple-drug treatment of hypertension. Postgraduate medicine, 2011, Volume: 123, Issue:6 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Design; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tetrazoles; Valine; Valsartan	2011
Aliskiren, amlodipine and hydrochlorothiazide triple combination for hypertension. Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:3 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Treatment Outcome	2012
The single pill triple combination of aliskiren, amlodipine, and hydrochlorothiazide in the treatment of hypertension. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:16 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Treatment Outcome	2012
Aliskiren/amlodipine vs. aliskiren/hydrochlorothiazide in hypertension: indirect meta-analysis of trials comparing the two combinations vs. monotherapy. American journal of hypertension, 2014, Volume: 27, Issue:2 Topics: Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Renin	2014

Trials

27 trial(s) available for hydrochlorothiazide and aliskiren

Article	Year
Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide. Journal of hypertension, 2007, Volume: 25, Issue:1 Topics: Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Least-Squares Analysis; Male; Middle Aged; Renin; Time Factors; Treatment Outcome	2007
Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Patient Compliance; Ramipril; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles	2007
Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan. American journal of hypertension, 2007, Volume: 20, Issue:1 Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan	2007
Direct Renin inhibition with aliskiren in obese patients with arterial hypertension. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:5 Topics: Administration, Oral; Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diastole; Double-Blind Method; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Obesity; Renin; Systole; Tetrazoles; Treatment Outcome	2007
Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial. Journal of hypertension, 2008, Volume: 26, Issue:3 Topics: Administration, Oral; Adult; Amides; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Time Factors; Treatment Outcome	2008
Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide. Circulation, 2009, Jan-27, Volume: 119, Issue:3 Topics: Administration, Oral; Adult; Aged; Amides; Antihypertensive Agents; Double-Blind Method; Dyspepsia; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Single-Blind Method; Time	2009
Efficacy of aliskiren/hydrochlorothiazide single-pill combinations in aliskiren non-responders. Blood pressure. Supplement, 2008, Volume: 2 Topics: Adolescent; Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Combinations; Drug Resistance; Endpoint Determination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome; Young Adult	2008
Antihypertensive efficacy and tolerability of aliskiren/hydrochlorothiazide (HCT) single-pill combinations in patients who are non-responsive to HCT 25 mg alone. Current medical research and opinion, 2009, Volume: 25, Issue:4 Topics: Adult; Amides; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Young Adult	2009
Aliskiren-based therapy lowers blood pressure more effectively than hydrochlorothiazide-based therapy in obese patients with hypertension: sub-analysis of a 52-week, randomized, double-blind trial. Journal of hypertension, 2009, Volume: 27, Issue:7 Topics: Amides; Antihypertensive Agents; Double-Blind Method; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Obesity; Placebos	2009
Combination therapy with various combinations of aliskiren, valsartan, and hydrochlorothiazide in hypertensive patients not adequately responsive to hydrochlorothiazide alone. Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:6 Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2009
Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension. Current medical research and opinion, 2010, Volume: 26, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amides; Antihypertensive Agents; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan; Young Adult	2010
Efficacy and tolerability of aliskiren 300 mg/hydrochlorothiazide 25 mg (± amlodipine 5 mg) in hypertensive patients not controlled by candesartan 32 mg plus HCT 25 mg. Current medical research and opinion, 2011, Volume: 27, Issue:1 Topics: Adult; Aged; Algorithms; Amides; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Failure; Treatment Outcome	2011
Aliskiren alone or in combination with hydrochlorothiazide in patients with the lower ranges of stage 2 hypertension: The ACQUIRE randomized double-blind study. Journal of clinical hypertension (Greenwich, Conn.), 2010, Volume: 12, Issue:12 Topics: Aged; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Treatment Outcome	2010
Comparison of aliskiren/hydrochlorothiazide combination therapy with hydrochlorothiazide monotherapy in older patients with stage 2 systolic hypertension: results of the ACTION study. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:3 Topics: Age Factors; Aged; Amides; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Body Mass Index; Disease Progression; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Health Status Indicators; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Systole; Treatment Outcome; United States	2011
Peripheral and central blood pressure responses of combination aliskiren/hydrochlorothiazide and amlodipine monotherapy in African American patients with stage 2 hypertension: the ATLAAST trial. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:5 Topics: Adult; Amides; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Brachial Artery; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Headache; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Treatment Outcome	2011
Pharmacokinetics and pharmacodynamics of aliskiren/hydrochlorothiazide single-pill combination tablets and free combination of aliskiren and hydrochlorothiazide. Journal of clinical pharmacology, 2012, Volume: 52, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Amides; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Least-Squares Analysis; Male; Middle Aged; Models, Biological; Renin; Tablets; Therapeutic Equivalency; Treatment Outcome; Young Adult	2012
Aliskiren as add-on therapy in the treatment of hypertensive diabetic patients inadequately controlled with valsartan/HCT combination: a placebo-controlled study. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2011, Oct-01, Volume: 11, Issue:5 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Dropouts; Potassium; Single-Blind Method	2011
Long-term safety and tolerability of the oral direct renin inhibitor aliskiren with optional add-on hydrochlorothiazide in patients with hypertension: a randomized, open-label, parallel-group, multicentre, dose-escalation study with an extension phase. Clinical drug investigation, 2011, Dec-01, Volume: 31, Issue:12 Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Time Factors; Young Adult	2011
Comparison of aliskiren/hydrochlorothiazide combination therapy and amlodipine monotherapy in patients with stage 2 systolic hypertension and type 2 diabetes mellitus. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:12 Topics: Amides; Amlodipine; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Systole	2011
Clinic and ambulatory blood pressure lowering effect of aliskiren/amlodipine/hydrochlorothiazide combination in patients with moderate-to-severe hypertension: a randomized active-controlled trial. Journal of hypertension, 2012, Volume: 30, Issue:10 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Severity of Illness Index; Single-Blind Method	2012
Aliskiren alone or in combination with hydrochlorothiazide in Hispanic/Latino patients with systolic blood pressure 160 mm Hg to <180 mm Hg (Aliskiren Alone or in Combination with Hydrochlorothiazide in Patients with Stage 2 Hypertension to Provide Quick Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:8 Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Hispanic or Latino; Humans; Hydrochlorothiazide; Hypertension; International Cooperation; Male; Middle Aged; Severity of Illness Index; Systole; Treatment Outcome	2012
Safety and efficacy of aliskiren/amlodipine/hydrochlorothiazide triple combination in patients with moderate to severe hypertension: a 54-week, open-label study. Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:12 Topics: Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Biological Availability; Blood Pressure; Drug Monitoring; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Pharmacovigilance; Severity of Illness Index; Treatment Outcome	2012
The influence of a direct renin inhibitor on the central blood pressure. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2013, Volume: 80, Issue:1 Topics: Adult; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Prospective Studies; Renin; Time Factors; Treatment Outcome	2013
Chronic renin inhibition lowers blood pressure and reduces upright muscle sympathetic nerve activity in hypertensive seniors. The Journal of physiology, 2013, Dec-01, Volume: 591, Issue:23 Topics: Aged; Amides; Antihypertensive Agents; Blood Pressure; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Muscles; Peroneal Nerve; Posture; Renin; Sodium Chloride Symporter Inhibitors; Sympathetic Nervous System	2013
The effect of aliskiren versus ramipril-based treatment on the Ambulatory Arterial Stiffness Index in hypertensive patients. International angiology : a journal of the International Union of Angiology, 2014, Volume: 33, Issue:1 Topics: Adult; Aged; Amides; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Drug Therapy, Combination; Fumarates; Greece; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Predictive Value of Tests; Ramipril; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Time Factors; Treatment Outcome; Vascular Stiffness; Vasodilator Agents	2014
Aliskiren alone or with other antihypertensives in the elderly with borderline and stage 1 hypertension: the APOLLO trial. European heart journal, 2014, Volume: 35, Issue:26 Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Potassium; Treatment Outcome	2014
Comparative Effect of a Renin Inhibitor and a Thiazide Diuretic on Renal Tissue Oxygenation in Hypertensive Patients. Kidney & blood pressure research, 2015, Volume: 40, Issue:5 Topics: Adult; Aged; Amides; Antihypertensive Agents; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Kidney; Male; Middle Aged; Oxygen Consumption; Prospective Studies; Renin; Single-Blind Method	2015

Other Studies

21 other study(ies) available for hydrochlorothiazide and aliskiren

Article	Year
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers. International journal of clinical practice, 2006, Volume: 60, Issue:11 Topics: Adolescent; Adult; Amides; Amlodipine; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2006
Antihypertensive therapies. Nature reviews. Drug discovery, 2007, Volume: 6, Issue:8 Topics: Amides; Antihypertensive Agents; Blood Pressure; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diuretics; Drug Design; Drug Industry; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Renin; Tetrazoles; Valine; Valsartan	2007
Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis. Current medical research and opinion, 2008, Volume: 24, Issue:4 Topics: Aged; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan	2008
Aliskiren/hydrochlorothiazide (Tekturna HCT) for hypertension. The Medical letter on drugs and therapeutics, 2008, Aug-25, Volume: 50, Issue:1293 Topics: Adult; Amides; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Renin	2008
Aliskiren for hypertension in adults. Drug and therapeutics bulletin, 2008, Volume: 46, Issue:10 Topics: Adult; Amides; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Renin; Treatment Outcome	2008
Antihypertensive efficacy of aliskiren: is hydrochlorothiazide an appropriate benchmark? Circulation, 2009, Jan-27, Volume: 119, Issue:3 Topics: Amides; Antihypertensive Agents; Benchmarking; Fumarates; Humans; Hydrochlorothiazide; Hypertension	2009
Aliskiren/hydrochlorothiazide combination: in mild to moderate hypertension. Drugs, 2009, Volume: 69, Issue:7 Topics: Amides; Antihypertensive Agents; Blood Pressure; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension	2009
Aliskiren + hydrochlorothiazide. Prescrire international, 2010, Volume: 19, Issue:106 Topics: Amides; Antihypertensive Agents; Drug Combinations; Fumarates; Humans; Hydrochlorothiazide; Hypertension	2010
Managing erectile dysfunction in hypertensive patients. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:6 Topics: Amides; Antihypertensive Agents; Benzopyrans; Chlorthalidone; Ethanolamines; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Impotence, Vasculogenic; Losartan; Male; Middle Aged; Nebivolol; Risk Factors	2011
Simultaneous determination of aliskiren and hydrochlorothiazide from their pharmaceutical preparations using a validated stability-indicating MEKC method. Journal of separation science, 2011, Volume: 34, Issue:15 Topics: Amides; Chromatography, Micellar Electrokinetic Capillary; Fumarates; Hydrochlorothiazide; Pharmaceutical Preparations; Reproducibility of Results	2011
Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats. Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:3 Topics: Albuminuria; Amides; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Fumarates; Hydrochlorothiazide; Inflammation; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin; Streptozocin	2012
Effectiveness and safety of aliskiren and aliskiren hydrochlorothiazide (HCT) in a multiethnic, real-world setting. Advances in therapy, 2013, Volume: 30, Issue:2 Topics: Adult; Amides; Antihypertensive Agents; Asian People; Drug Combinations; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Treatment Outcome	2013
Use of aliskiren in Latin America in a real-world setting: aliskiren in Latin America Study (ALAS). Therapeutic advances in cardiovascular disease, 2013, Volume: 7, Issue:4 Topics: Adult; Aged; Ambulatory Care; Amides; Antihypertensive Agents; Blood Pressure; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Latin America; Male; Middle Aged; Prospective Studies; Renin; Young Adult	2013
Simultaneous determination of aliskiren and hydrochlorothiazide in tablets and spiked human urine by ion-pair liquid chromatography. Die Pharmazie, 2013, Volume: 68, Issue:12 Topics: Amides; Antihypertensive Agents; Calibration; Chromatography, High Pressure Liquid; Diuretics; Fumarates; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Indicators and Reagents; Limit of Detection; Quality Control; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets	2013
Simultaneous determination of aliskiren hemifumarate, amlodipine besylate, and hydrochlorothiazide in their triple mixture dosage form by capillary zone electrophoresis. Journal of separation science, 2014, Volume: 37, Issue:9-10 Topics: Amides; Amlodipine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Fumarates; Hydrochlorothiazide	2014
Development and validation of a HPLC-PDA bioanalytical method for the simultaneous estimation of Aliskiren and Amlodipine in human plasma. Biomedical chromatography : BMC, 2015, Volume: 29, Issue:3 Topics: Acetonitriles; Amides; Amlodipine; Chemical Precipitation; Chromatography, High Pressure Liquid; Drug Stability; Fumarates; Humans; Hydrochlorothiazide; Limit of Detection; Sensitivity and Specificity	2015
Effect of aliskiren on circulating endothelial progenitor cells and vascular function in patients with type 2 diabetes and essential hypertension. American journal of hypertension, 2015, Volume: 28, Issue:1 Topics: Aged; Amides; Antihypertensive Agents; Arterial Pressure; Biomarkers; Cells, Cultured; Diabetes Mellitus, Type 2; Diuretics; Drug Substitution; Endothelial Progenitor Cells; Endothelium, Vascular; Female; Fumarates; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pilot Projects; Time Factors; Treatment Outcome; Vascular Stiffness; Vasodilation; Ventricular Function, Left	2015
Simultaneous Determination of Aliskiren Hemifumarate, Amlodipine Besylate and Hydrochlorothiazide in Spiked Human Plasma Using UPLC-MS/MS. Journal of chromatographic science, 2015, Volume: 53, Issue:7 Topics: Amides; Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Fumarates; Humans; Hydrochlorothiazide; Limit of Detection; Liquid-Liquid Extraction; Reproducibility of Results; Tandem Mass Spectrometry	2015
Continuous Wavelet Transform, a powerful alternative to Derivative Spectrophotometry in analysis of binary and ternary mixtures: A comparative study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Dec-05, Volume: 151 Topics: Algorithms; Amides; Amlodipine; Bisoprolol; Complex Mixtures; Fumarates; Hydrochlorothiazide; Reproducibility of Results; Signal Processing, Computer-Assisted; Signal-To-Noise Ratio; Spectrophotometry; Wavelet Analysis	2015
Mean centering of double divisor ratio spectra, a novel spectrophotometric method for analysis of ternary mixtures. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Jan-15, Volume: 153 Topics: Amides; Amlodipine; Analysis of Variance; Chromatography, High Pressure Liquid; Fumarates; Hydrochlorothiazide; Methanol; Models, Molecular; Reference Standards; Reproducibility of Results; Spectrophotometry; Tablets	2016
Resolution of overlapped spectra for the determination of ternary mixture using different and modified spectrophotometric methods. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Aug-05, Volume: 165 Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Fumarates; Hydrochlorothiazide; Spectrophotometry, Ultraviolet; Tablets	2016