hydrochloric acid has been researched along with indomethacin in 117 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (27.35) | 18.7374 |
| 1990's | 45 (38.46) | 18.2507 |
| 2000's | 24 (20.51) | 29.6817 |
| 2010's | 16 (13.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eakins, KE; Ishikawa, R; Jenkins, RM; Paterson, CA; Paterson, E | 1 |
| Whittle, BJ | 1 |
| Szelenyi, I; Thiemer, K | 1 |
| Paál, T | 1 |
| Kohút, A; Maheĺová, O; Mirossay, L; Mojzís, J | 1 |
| Matsumoto, J; Okabe, S; Takeuchi, K; Ueshima, K | 1 |
| Johnson, BR; Morales, RE; Szabo, S | 1 |
| Azpiroz, F; Guarner, F; Lugea, A; Malagelada, JR; Salas, A | 1 |
| Carter, KJ; Goddard, PJ; Silen, W; Yanaka, A | 1 |
| Hata, Y; Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Sugimoto, T; Terano, A | 1 |
| Meddings, JB; Vaananen, PM; Wallace, JL | 1 |
| Aly, A; Hellström, PM; Jaramillo, E; Johansson, C; Smedfors, B | 1 |
| Macherey, HJ; Petersen, KU | 1 |
| Cenarruzabeitia, E; Craciunescu, G; Frechilla, D; Lasheras, B; Parrondo, E; Ucelay, M | 1 |
| Ishida, Y; Ogihara, Y; Okabe, S | 1 |
| McKnight, GW; Wallace, JL | 1 |
| Akahori, F; Arai, S; Kubo, G; Masaoka, T; Yamada, F | 1 |
| Aly, A; Johansson, C; Smedfors, B; Theodorsson, E | 1 |
| Ageel, AM; al-Yahya, MA; Mossa, JS; Parmar, NS; Rafatullah, S; Tariq, M | 1 |
| Cirino, G; De Nucci, G; MacNaughton, WK; McKnight, W; Wallace, JL | 1 |
| Brunsson, I; Jodal, M; Lundgren, O; Sjöqvist, A | 1 |
| Bilski, J; Carter, SR; Konturek, SJ; Kosmala, M; Slomiany, A; Slomiany, BL | 1 |
| Nakagawa, M; Okabe, S; Takeuchi, K; Tanaka, H | 1 |
| Balaa, MA | 1 |
| Nishiwaki, H; Okabe, S; Okada, M; Takeuchi, K | 1 |
| Kohút, A; Mirossay, L; Nicák, A | 1 |
| MacNaughton, WK; Morris, GP; Williamson, TE | 1 |
| Hinchey, EJ; Lough, JO; Mesereau, WA | 1 |
| Castell, DO; Geisinger, KR; Hassan, M; Huang, D; Katz, PO; Wu, WC | 1 |
| Ikeda, T; Kurebayashi, Y; Osada, Y | 1 |
| Fedde, MR; Orr, JA; Scheid, P; Shams, H | 1 |
| Burke, J; Hales, C; Jung, W; Shinozawa, Y | 1 |
| Goldhaber, P; Rabadjija, L | 1 |
| Furukawa, O; Nishiwaki, H; Okabe, S; Takeuchi, K; Tanaka, H | 1 |
| Furukawa, O; Nishiwaki, H; Okabe, S; Takeuchi, K | 1 |
| Awane, Y; Miyake, H; Okabe, S | 1 |
| Isenberg, JI; Johansson, C; Smedfors, B | 1 |
| Tagami, H; Tanaka, I | 1 |
| Doteuchi, M; Hirose, F; Mizui, T; Shimono, N | 1 |
| Nobuhara, Y; Takeuchi, K | 1 |
| Borka, L | 1 |
| Coutinho, CB; Yesair, DW | 1 |
| Evangelista, S; Maggi, CA; Meli, A | 1 |
| Kyogoku, K; Mori, Y; Nakazima, M; Shinozaki, A; Suwa, T | 1 |
| Allen, A; Garner, A; Hutton, D; McQueen, S | 1 |
| Brunsson, I; Cassuto, J; Jodal, M; Lundgren, O; Sjöqvist, A | 1 |
| Andersson, H; Nylander, O; Sababi, M; Wilander, E | 1 |
| al-Gharably, NM; al-Harbi, MM; al-Shabanah, OA; Islam, MW | 1 |
| Albeck, M; Kalechman, Y; Sredni, B; Xu, RH | 1 |
| Attaguile, G; Caruso, A; Pennisi, G; Savoca, F | 1 |
| Ainsworth, MA; Andersen, NJ; Glad, H; Olsen, O; Schaffalitzky de Muckadell, OB; Svendsen, P | 1 |
| Johansson, C; Smedfors, B; Theodorsson, E | 1 |
| Chey, WY; Scheiman, JM; Soudah, HC; Taylor, SD | 1 |
| Karmeli, F; Okon, E; Rachmilewitz, D; Samuni, A | 1 |
| Domingo, A; Guarner, F; Lugea, A; Malagelada, JR; Mourelle, M; Salas, A | 1 |
| Gutiérrez-Cabano, CA | 1 |
| Guarner, F; Lugea, A; Malagelada, JR; Salas, A | 1 |
| Karádi, O; Király, A; Matus, Z; Mózsik, G; Sütö, G; Tóth, G; Vincze, A | 1 |
| Kato, S; Okabe, S; Takeuchi, K | 1 |
| Kato, S; Ohuchi, T; Okabe, S; Takeuchi, K | 1 |
| Diwan, PV; Krishna, DR; Sastry, MS | 1 |
| al-Moutairy, AR; Tariq, M | 1 |
| Kohgo, Y; Okumura, T; Onodera, S; Shoji, E | 1 |
| Hatakeyama, Y; Ohtsuka, M; Shimomura, K; Tomoi, M | 1 |
| Ching, CK; Cho, CH; Ko, JK; Lam, SK | 1 |
| Clayton, NM; Oakley, I; Trevethick, MA; Williams, LV | 1 |
| Isoi, T; Kakita, T; Kataoka, H; Kiso, T; Ohtsubo, Y; Shinkawa, R; Shogaki, T | 1 |
| Fukutomi, H; Goto, K; Hassan, M; Hayashi, T; Iwata, R; Kashimura, H; Matsumaru, K; Muto, H; Nakahara, A; Tanaka, N | 1 |
| Abdel Salam, OM; Mózsik, G; Szolcsányi, J | 1 |
| Al Moutaery, AR; Tariq, M | 2 |
| Gunawan, ES; Hori, M; Kawano, S; Matsui, H; Nagano, K; Nakama, A; Sawaoka, H; Takei, Y; Tsuji, S; Tsujii, M | 1 |
| Holm, L; Synnerstad, I | 1 |
| Fändriks, L; Holm, M; Johansson, B; Pettersson, A | 1 |
| Furukawa, O; Kawauchi, S; Sugamoto, S; Takeuchi, K; Yagi, K | 1 |
| Dhuley, JN; Naik, SR | 1 |
| Hirata, T; Kato, S; Kunikata, T; Takeuchi, K; Tanaka, A; Yamamoto, H | 1 |
| Flemström, G; Hellgren, S; Nylander, O | 1 |
| Gretzer, B; Maricic, N; Peskar, BM; Respondek, M; Schuligoi, R | 1 |
| Matsueda, K; Muraoka, A; Shoda, R; Uchida, M; Yamato, S | 1 |
| Kato, S; Takeuchi, K; Tanaka, A | 1 |
| Araki, H; Komoike, Y; Suzuki, K; Takeuchi, K; Umeda, M | 1 |
| Furukawa, O; Kawauch, S; Mimaki, TH; Sugamoto, S; Takeuchi, K | 1 |
| Ohmori, K; Tamura, T; Yokoyama, T | 1 |
| Kato, S; Matsumoto, M; Nakashima, M; Ogawa, Y; Takeeda, M; Takeuchi, K | 1 |
| Asao, Y; Matsuda, H; Morikawa, T; Pongpiriyadacha, Y; Yoshikawa, M | 1 |
| Almeida, AB; Brito, AR; De Azevedo, MB; Durán, N; Haun, M; Justo, GZ; Melo, PS | 1 |
| Durán, N; Haun, M; Hiruma-Lima, CA; Melo, PS; Souza-Brito, AR | 1 |
| Al-Howiriny, T; Al-Sohaibani, M; El-Tahir, K; Rafatullah, S | 1 |
| Alexander, JS; Itoh, M; Joh, T; Oshima, T; Seno, K; Suzuki, H; Takezono, Y; Yokoyama, Y | 1 |
| Hoshino, T; Mizushima, T; Tanaka, K; Tomisato, W; Tsuchiya, T; Tsutsumi, S | 1 |
| Amornlerdpison, D; Kanjanapothi, D; Rujjanawate, C | 1 |
| Aihara, E; Hayashi, M; Sasaki, Y; Takeuchi, K | 1 |
| Farombi, EO; Olaleye, SB | 1 |
| Bartuzi, Z; McCallum, R; Poplawski, C; Sarosiek, J; Sosnowski, D; Szaflarska-Popławska, A | 1 |
| Matsuda, H; Nagatomo, A; Ochi, M; Yoshikawa, M | 1 |
| Gulfraz, M; Kakub, G | 1 |
| Choi, J; Jung, HJ; Nam, JH; Park, HJ | 1 |
| Johri, RK; Khajuria, A; Khajuria, RK; Qazi, GN; Singh, J; Singh, S; Taneja, SC | 1 |
| Batista, LM; de Almeida, AB; de Pietro Magri, L; dos Santos, LC; Hiruma-Lima, CA; Souza Brito, AR; Vilegas, W | 1 |
| Cechinel Filho, V; Clasen, BK; de Andrade, SF; Gandolfi, RB; Gimenez, A; Lemos, M; Ticona, JC; Zanatta, F | 1 |
| Bachri, MS; Choi, J; Choi, JS; Kim, WB; Lee, BI; Lee, JD; Lee, KR; Lee, KT; Nugroho, A; Park, HJ | 1 |
| Hara, H; Kakino, M; Ogawa, K; Oyagi, A | 1 |
| Carvalho, KI; Chaves, MH; Fernandes, HB; Freitas, FF; Leite, JR; Miura, LM; Oliveira, FA; Oliveira, RC; Pereira, SS; Piauilino, CA; Soares, PM | 1 |
| Caldas, GF; da Costa, JG; da Nóbrega, RF; da Silva, JB; do Amaral Costa, IM; Rodrigues, FF; Wanderley, AG | 1 |
| An, SS; Battafarano, RJ; Burrows, WM; Damera, G; Deshpande, DA; Dubose, TD; Panettieri, RA; Penn, RB; Saxena, H; Tiegs, BC; Yan, H | 1 |
| Al-Amin, M; Hossain, CF; Sultana, GN | 1 |
| Işıklan, N; Küçükbalcı, G | 1 |
| Amang, PA; Mefe, MN; Patamaken, SA; Tan, PV | 1 |
| Areche, C; Cañete, A; Garcia-Beltrán, O; San Martin, A; Sepulveda, B; Simirgiotis, M | 1 |
| Costa, EA; da Costa, HB; da Silva, DM; de Paula, JR; Galdino, PM; Ghedini, PC; Martins, JL; Rodrigues, OR; Romão, W; Vaz, BG | 1 |
| Choi, WS; Lee, GR; Lee, SE; Oh, S; Son, DJ | 1 |
| Boeing, T; Bordignon Somensi, L; de Moura Burci, L; Faloni de Andrade, S; Filho, VC; Mota da Silva, L; Santin, JR; Schlickmann, F | 1 |
| Andrade, TU; Costa, HB; Endringer, DC; Lenz, D; Nogueira, BV; Pereira, AC; Pereira, TM; Romão, W; Scherer, R | 1 |
| Boeing, T; Breviglieri, E; Cechinel Filho, V; Cury, BJ; de Andrade, SF; Gimenez, A; Mota da Silva, L; Somensi, LB | 1 |
| Gao, Y; Jia, D; Williams, GR | 1 |
| Almeida, MO; Andrade, SF; Arruda, C; Bastos, JK; Boeing, T; Casoti, R; Costa, P; da Silva, LM; da Silva, RCMVAF; Dos Santos, AC; Lemos, M; Mariott, M; Somensi, LB; Souza, P; Stein, BP | 1 |
1 review(s) available for hydrochloric acid and indomethacin
| Article | Year |
|---|---|
[Gastrointestinal cytoprotection by prostaglandin E and EP receptor subtypes].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytoprotection; Dinoprostone; Ethanol; Gastric Mucosa; Humans; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Receptors, Prostaglandin E | 2001 |
116 other study(ies) available for hydrochloric acid and indomethacin
| Article | Year |
|---|---|
The ocular hypertensive response following experimental acid burns in the rabbit eye.
Topics: Animals; Aqueous Humor; Burns, Chemical; Eye Burns; Eye Proteins; Hydrochloric Acid; Hydrogen-Ion Concentration; Imidazoles; Indomethacin; Intraocular Pressure; Prostaglandins; Rabbits | 1979 |
The gastric mucosal microcirculation during erosion formation in the rat.
Topics: Animals; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Microcirculation; Rats; Regional Blood Flow; Sodium Chloride; Stomach Ulcer; Taurocholic Acid | 1977 |
Distention ulcer as a model for testing of drugs for ulcerogenic side effects.
Topics: Animals; Aspirin; Disease Models, Animal; Hydrochloric Acid; Indomethacin; Male; Rats; Stomach; Stomach Ulcer; Stress, Physiological; Time Factors | 1978 |
[Study of the buffer effect in the qualitative analysis of drugs. II].
Topics: Alkaloids; Buffers; Carboxylic Acids; Chlorobenzoates; Drug Contamination; Hydrochloric Acid; Hydrolysis; Indomethacin; Lactates; Methods; Piperidines; Piperidones; Prenylamine | 1975 |
Effect of sialoadenectomy on stomach lesions induced by indomethacin and ethanol in relation to gastric vascular permeability, the gastrin level and HCl secretion in rats.
Topics: Animals; Capillary Permeability; Epidermal Growth Factor; Ethanol; Gastrins; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Wistar; Salivary Glands; Stomach; Stomach Ulcer | 1992 |
Role of capsaicin-sensitive afferent neurons in mucosal blood flow response of rat stomach induced by mild irritants.
Topics: Animals; Capsaicin; Denervation; Gastric Acidity Determination; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Irritants; Male; Neurons, Afferent; Rats; Rats, Inbred Strains; Regional Blood Flow; Sodium Chloride | 1992 |
Endothelin induces vascular and mucosal lesions, enhances the injury by HCl/ethanol, and the antibody exerts gastroprotection.
Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Ethanol; Female; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Microcirculation; Rats; Stomach | 1992 |
Duodenal mucosal resistance to intraluminal acid in the rat: role of adaptive cytoprotection.
Topics: 16,16-Dimethylprostaglandin E2; Adaptation, Physiological; Animals; Bicarbonates; Dinoprostone; Duodenum; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains | 1992 |
Prostaglandin stimulates Cl(-)-HCO3- exchange in amphibian oxynticopeptic cells.
Topics: Animals; Carrier Proteins; Chloride-Bicarbonate Antiporters; Electrophysiology; Gastric Fundus; Homeostasis; Hydrochloric Acid; Hydrogen; Hydrogen-Ion Concentration; Indomethacin; Omeprazole; Parietal Cells, Gastric; Prostaglandins; Rana catesbeiana; Rest | 1992 |
The effect of cimetidine on adaptive cytoprotection by mild irritant dose of HCl in the rat gastric mucosa.
Topics: Adaptation, Physiological; Animals; Cimetidine; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Irritants; Male; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Role of oxygen-derived free radicals in indomethacin-induced gastric injury.
Topics: Allopurinol; Animals; Catalase; Chromium Radioisotopes; Deferoxamine; Free Radical Scavengers; Free Radicals; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Oxygen; Rats; Rats, Inbred Strains; Stomach Ulcer; Superoxide Dismutase | 1991 |
Cholinergic mechanisms involved in release and effect of prostaglandin E2 in HCl-stimulated duodenal HCO-3 secretion in the conscious rat.
Topics: Animals; Atropine; Bicarbonates; Dinoprostone; Hexamethonium; Hexamethonium Compounds; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic | 1990 |
Acid-induced increase in electrical conductance of guinea pig duodenal mucosa in vitro. Temporary protection by combined effects of bicarbonate and prostaglandin E2.
Topics: Animals; Bicarbonates; Dinoprostone; Duodenum; Electric Conductivity; Furosemide; Guinea Pigs; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Male; Sodium; Sodium Hydroxide | 1991 |
Protection by copper (II) complexes in various models of ulceration in rat.
Topics: Animals; Anti-Ulcer Agents; Copper; Gastric Acid; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Inbred Strains; Stomach Ulcer | 1991 |
Effects of a crude extract of a marine dinoflagellate, containing dimethyl-beta-propiothetin, on HCl.ethanol-induced gastric lesions and gastric secretion in rats.
Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Ethanol; Eukaryota; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Prostaglandins; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer; Sulfonium Compounds | 1990 |
The mucoid cap over superficial gastric damage in the rat. A high-pH microenvironment dissipated by nonsteroidal antiinflammatory drugs and endothelin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Endothelins; Endothelium, Vascular; Fibrin; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Male; Mucus; Naproxen; Peptides; Rats; Rats, Inbred Strains; Regional Blood Flow; Time Factors | 1990 |
Effects of liver extract from the ocean sunfish (Mola mola) on acute gastric lesions in the rat.
Topics: Animals; Cimetidine; Hydrochloric Acid; Indomethacin; Liver Extracts; Male; Perciformes; Rats; Rats, Inbred Strains; Seawater; Stomach Ulcer; Stress, Physiological | 1990 |
Role of VIP in local control of secretion.
Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Dinoprostone; Duodenum; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Rats; Vasoactive Intestinal Peptide | 1990 |
Gastroprotective activity of ginger zingiber officinale rosc., in albino rats.
Topics: Animals; Aspirin; Drugs, Chinese Herbal; Ethanol; Female; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Inbred Strains; Reserpine; Sodium Chloride; Sodium Hydroxide; Stomach Ulcer; Stress, Physiological | 1989 |
Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.
Topics: Animals; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Ethanol; Ginkgolides; Hydrochloric Acid; Indomethacin; Lactones; Male; Nitroprusside; Peptic Ulcer Hemorrhage; Peptides; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Stomach; Stomach Ulcer; Vasoconstriction | 1989 |
Mechanisms underlying the intestinal fluid secretion evoked by nociceptive serosal stimulation of the rat.
Topics: Animals; Biological Transport; Bradykinin; Deoxycholic Acid; Ethanol; Female; Hexamethonium; Hexamethonium Compounds; Histamine; Hydrochloric Acid; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Intestinal Secretions; Jejunum; Male; Nociceptors; Prostaglandins; Rats; Rats, Inbred Strains; Reflex; Serotonin | 1985 |
Intestinal release of mucin in response to HCl and taurocholate: effect of indomethacin.
Topics: Animals; Bicarbonates; Centrifugation, Density Gradient; Chromatography, Gel; Dogs; Duodenum; Female; Gastric Mucosa; Hydrochloric Acid; Ileum; Indomethacin; Intestinal Mucosa; Jejunum; Lipids; Male; Mucins; Taurocholic Acid | 1987 |
Effects of mepirizole and basic antiinflammatory drugs on HCl-ethanol-induced gastric lesions in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Benzydamine; Epirizole; Ethanol; Ethylmaleimide; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Piperazines; Pyrazoles; Pyridines; Pyrimidines; Rats; Rats, Inbred Strains; Thienopyridines | 1989 |
Release of protective products, different from prostaglandins, by rat stomachs exposed to mild irritant.
Topics: Animals; Dinoprostone; Ethanol; Gastric Emptying; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Irritants; Male; Rats; Rats, Inbred F344; Sodium Chloride | 1989 |
Mucosal protective action of histamine against gastric lesions induced by HCl in rats: importance of antigastric motor activity mediated by H2-receptors.
Topics: Animals; Cimetidine; Dimaprit; Gastric Acid; Gastric Mucosa; Gastrointestinal Motility; Histamine; Hydrochloric Acid; Indomethacin; Male; Pyridines; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea; Tripelennamine | 1988 |
Comparison of the ulcerogenicity of indomethacin and the gastric secretion in verapamil-treated rats.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Verapamil | 1988 |
Adaptive cytoprotection by 0.25 M HCl is truly "cytoprotective" and may not depend upon elevated levels of prostaglandin synthesis.
Topics: Animals; Cell Survival; Ethanol; Evoked Potentials; Female; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Potassium; Prostaglandins; Rats; Rats, Inbred Strains | 1988 |
Factors in formation and prevention of bandlike gastric lesions in the rat.
Topics: Animals; Ethanol; Female; Gastric Mucosa; Gentian Violet; Hydrochloric Acid; Indomethacin; Necrosis; Prostaglandins; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains | 1988 |
Acid-induced esophagitis in cats is prevented by sucralfate but not synthetic prostaglandin E.
Topics: Animals; Cats; Esophagitis, Peptic; Esophagoscopy; Esophagus; Hydrochloric Acid; Hyperplasia; Indomethacin; Prostaglandins E, Synthetic; Sucralfate | 1988 |
Cytoprotective action of cetraxate against HCl.ethanol-induced gastric lesion in rats.
Topics: Animals; Anti-Ulcer Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Microscopy, Electron, Scanning; Necrosis; Rats; Rats, Inbred Strains; Tranexamic Acid | 1988 |
HCl infusion stimulates the release of a substance from the blood which alters breathing and blood pressure.
Topics: Animals; Blood Platelets; Blood Pressure; Cats; Female; Hydrochloric Acid; Indomethacin; Infusions, Intravenous; Male; Respiration; Thromboxanes | 1988 |
Ibuprofen prevents synthetic smoke-induced pulmonary edema.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Drug Evaluation, Preclinical; Epoprostenol; Germ-Free Life; Hemodynamics; Hydrochloric Acid; Ibuprofen; Indomethacin; Lung; Male; Pulmonary Edema; Rats; Rats, Inbred Strains; Smoke; Thromboxane B2 | 1986 |
H+ stimulation of cell-mediated bone resorption in tissue culture.
Topics: Animals; Bone Resorption; Calcitonin; Calcium; Collagen; Culture Techniques; Hydrochloric Acid; Hydrogen; Indomethacin; Mice; Skull; Stimulation, Chemical | 1987 |
Impairment of acid-neutralizing capacity and lesion formation in the rat duodenum during hemorrhagic shock: comparative study with indomethacin.
Topics: Acid-Base Equilibrium; Animals; Duodenum; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Male; Membrane Potentials; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Shock, Hemorrhagic | 1987 |
Cytoprotective action of histamine against 0.6 N HCl-induced gastric mucosal injury in rats; comparative study with adaptive cytoprotection induced by exogenous acid.
Topics: Adaptation, Physiological; Animals; Cimetidine; Gastric Acid; Gastric Mucosa; Histamine; Hydrochloric Acid; Indomethacin; Male; Membrane Potentials; Omeprazole; Rats; Rats, Inbred Strains | 1987 |
Cytoprotective effects of NC-1300 and omeprazole on Hcl . ethanol-induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Ethanol; Ethylmaleimide; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Omeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer; Sulfones | 1986 |
Effect of graded doses of intraluminal H+, prostaglandin E2, and inhibition of endogenous prostaglandin synthesis on proximal duodenal bicarbonate secretion in unanesthetized rat.
Topics: Animals; Bicarbonates; Dinoprostone; Duodenum; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Male; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
[Effects of 2-benzyloxycarbonylphenyl trans-4-guanidinomethylcyclohexanecarboxylate hydrochloride monohydrate (TKG01) and its clathrate compound with beta-cyclodextrin (TA903) on experimental gastric ulcers and gastric secretion in rats].
Topics: Animals; Anti-Ulcer Agents; beta-Cyclodextrins; Cyclodextrins; Cyclohexanecarboxylic Acids; Dextrins; Ethanol; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Pepsin A; Rats; Rats, Inbred Strains; Starch; Stomach Ulcer; Stress, Physiological | 1985 |
Gastric antral ulcers induced by a combination of acid, indomethacin and ischemia in rats.
Topics: Animals; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Ischemia; Male; Pyloric Antrum; Rats; Rats, Inbred Strains; Stomach Ulcer | 1985 |
Inhibition of gastric motor activity by 16,16-dimethyl prostaglandin E2. A possible explanation of cytoprotection.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Drug Interactions; Ethanol; Gastric Mucosa; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Male; Muscle Contraction; Necrosis; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Sodium Chloride; Sodium Hydroxide; Transducers, Pressure | 1985 |
The polymorphism of indomethacine. New modifications, their melting behavior and solubility.
Topics: Chemical Phenomena; Chemistry; Crystallography; Hydrochloric Acid; Indomethacin; Solubility; Solvents; Spectrophotometry, Infrared; Temperature; Water | 1974 |
Method for extraction and separation of drugs and metabolites from biological tissue.
Topics: Animals; Bile; Carbon Isotopes; Chemical Phenomena; Chemistry; Chloroform; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Citrates; Drug Stability; Feces; Fluorine; Hydrocarbons, Halogenated; Hydrochloric Acid; Indoleacetic Acids; Indomethacin; Ions; Kidney; Liver; Methanol; Phenylbutazone; Rats; Salicylates; Sodium Hydroxide; Solubility; Spectrophotometry; Time Factors; Tromethamine; Ultraviolet Rays | 1970 |
The effect of levamisole on gastric ulcers induced in the rat by anti-inflammatory and necrotizing agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Ethanol; Hydrochloric Acid; Indomethacin; Levamisole; Male; Piroxicam; Rats; Rats, Inbred Strains; Stomach Ulcer; Thiazines | 1984 |
Cytoprotective effect of SU-88, an anti-ulcer agent, in the rat.
Topics: Animals; Anti-Ulcer Agents; Cell Survival; Chalcone; Chalcones; Cimetidine; Dinoprostone; Ethanol; Gastric Mucosa; Glycoproteins; Hydrochloric Acid; Indomethacin; Male; Mucus; Propiophenones; Prostaglandins E; Rats; Rats, Inbred Strains; Stomach Ulcer | 1984 |
Gastric and duodenal surface mucus gel thickness in rat: effects of prostaglandins and damaging agents.
Topics: Animals; Dinoprostone; Duodenum; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Male; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains | 1983 |
The effect of intestinal fluid transport of exposing the serosa to hydrochloric acid. A study of mechanisms.
Topics: Animals; Atropine; Cats; Female; Hexamethonium Compounds; Hydrochloric Acid; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Jejunum; Lidocaine; Male; Rats; Rats, Inbred Strains; Tetrodotoxin | 1982 |
Prostaglandins reduce hydrochloric acid-induced increase in duodenal mucosal permeability by a mechanism not related to stimulation of alkaline secretion.
Topics: Animals; Bicarbonates; Chromium Radioisotopes; Dinoprostone; Duodenum; Edetic Acid; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Male; Permeability; Prostaglandins; Rats; Rats, Sprague-Dawley | 1995 |
Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Ethanol; Female; Fish Oils; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Hypothermia; Indomethacin; Male; Pylorus; Rats; Rats, Wistar; Reserpine; Sodium Hydroxide; Stomach Ulcer | 1995 |
The cytoprotective effect of the immunomodulator AS101 against hydrochloride induced gastric lesions.
Topics: Adjuvants, Immunologic; Animals; Dinoprostone; Dose-Response Relationship, Drug; Epidermal Growth Factor; Ethylenes; Female; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Injections, Intraperitoneal; Intubation, Gastrointestinal; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1995 |
Gastroprotective effect of aqueous extract of Cistus incanus L. in rats.
Topics: Animals; Ethanol; Flavonoids; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Medicine, Traditional; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin; Stomach Ulcer | 1995 |
Duodenal mucosal bicarbonate secretion in pigs is accompanied by compensatory changes in pancreatic and biliary HCO3- secretion.
Topics: Acid-Base Equilibrium; Animals; Bicarbonates; Bile Ducts, Intrahepatic; Blood Pressure; Duodenum; Female; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Intestinal Secretions; Misoprostol; Pancreas; Secretin; Swine | 1994 |
HCl-stimulated duodenal HCO3- secretion in conscious rat. Interactions among VIP, nicotinic receptor mechanisms, and prostaglandins.
Topics: Animals; Atropine; Bicarbonates; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Duodenum; Hexamethonium; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stimulation, Chemical; Time Factors; Vasoactive Intestinal Peptide; Wakefulness | 1994 |
Duodenal acidification and secretin, but not intraduodenal fat, inhibit human gastric acid secretion via prostaglandins.
Topics: Adolescent; Adult; Duodenum; Female; Gastric Acid; Gastric Mucosa; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Male; Oleic Acid; Oleic Acids; Prostaglandins; Secretin | 1994 |
A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats.
Topics: Animals; Aspirin; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Leukotrienes; Male; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sodium Chloride; Spin Labels; Stomach Ulcer; Superoxide Dismutase | 1994 |
Phosphatidylcholines as mediators of adaptive cytoprotection of the rat duodenum.
Topics: 16,16-Dimethylprostaglandin E2; Adaptation, Physiological; Animals; Detergents; Duodenum; Hydrochloric Acid; Indomethacin; Male; Mucus; Phosphatidylcholines; Phospholipids; Polidocanol; Polyethylene Glycols; Rats; Rats, Sprague-Dawley | 1994 |
Protection against necrotizing agents-induced gastric lesions in rats. Unrelated to inhibition of gastric motility.
Topics: Animals; Ethanol; Female; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Male; Papaverine; Rats; Rats, Wistar; Sodium Chloride; Sodium Compounds; Sodium Hydroxide; Stomach Ulcer; Verapamil | 1994 |
Influence of dietary fat on duodenal resistance to acid.
Topics: Animals; Dietary Fats; Dinoprostone; Dose-Response Relationship, Drug; Drug Resistance; Duodenum; Eicosapentaenoic Acid; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Linoleic Acids; Male; Oleic Acids; Rats; Rats, Sprague-Dawley | 1993 |
Vagal nerve and the gastric mucosal defense.
Topics: Animals; Capillary Permeability; Dinoprostone; Epoprostenol; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Rats; Rats, Sprague-Dawley; Stomach Diseases; Vagotomy; Vagus Nerve | 1993 |
Mechanism by which histamine increases gastric mucosal blood flow in the rat. Role of luminal H+.
Topics: Animals; Bicarbonates; Cimetidine; Drug Interactions; Gastric Acid; Gastric Mucosa; Glycine; Histamine; Hydrochloric Acid; Hydrogen; Indomethacin; Infusions, Intravenous; Male; Omeprazole; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium; Sodium Bicarbonate; Tripelennamine | 1993 |
Cytoprotective action of L-arginine against HCl-induced gastric injury in rats: involvement of nitric oxide?
Topics: Animals; Arginine; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrointestinal Motility; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1993 |
Comparative evaluation of ulcer prevention efficacy of orally, rectally and sublingually administered omeprazole in three acute gastric ulcer models in rats.
Topics: Administration, Oral; Administration, Rectal; Administration, Sublingual; Animals; Aspirin; Female; Hydrochloric Acid; Indomethacin; Ligation; Male; Models, Biological; Omeprazole; Peptic Ulcer; Rats; Rats, Wistar | 1993 |
Effect of vitamin E and selenium on hypothermic restraint stress and chemically-induced ulcers.
Topics: Animals; Antioxidants; Cold Temperature; Hydrochloric Acid; Immobilization; Indomethacin; Rats; Rats, Wistar; Reserpine; Selenium; Sodium Chloride; Sodium Hydroxide; Stomach Ulcer; Stress, Physiological; Vitamin E | 1996 |
Susceptibility to the development of gastric mucosal damage in OLETF rat not expressing the CCK-A receptor.
Topics: Animals; Ethanol; Gastric Mucosa; Genetic Predisposition to Disease; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Inbred Strains; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Thyrotropin-Releasing Hormone | 1996 |
Implication of sensory neurons in the diverse mechanisms of adaptive cytoprotection in the rat stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Capsaicin; Cell Differentiation; Cyclooxygenase Inhibitors; Denervation; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Stomach | 1996 |
The importance of gastric emptying and mucosal folds in the adaptive cytoprotection of mild irritants in rats.
Topics: Adaptation, Physiological; Animals; Anti-Ulcer Agents; Ethanol; Gastric Emptying; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Irritants; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach; Stomach Ulcer | 1995 |
The role of acid in the pathogenesis of indomethacin-induced gastric antral ulcers in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Histamine H2 Antagonists; Hydrochloric Acid; Indomethacin; Pyloric Antrum; Ranitidine; Rats; Stomach Ulcer; Triazoles | 1996 |
[Effects of Cuban analog (SWR-104SA), a new histamine H2 receptor antagonist, on gastric acid secretion and experimental ulcer formation].
Topics: Animals; Dioxolanes; Ethanol; Gastric Acid; Gastrointestinal Motility; Guinea Pigs; Histamine H2 Antagonists; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Sprague-Dawley; Spiro Compounds; Stomach Ulcer | 1996 |
Bosentan, a novel synthetic mixed-type endothelin receptor antagonist, attenuates acute gastric mucosal lesions induced by indomethacin and HCl in the rat: role of endogenous endothelin-1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Rats; Rats, Wistar; Regional Blood Flow; Stomach Ulcer; Sulfonamides; Time Factors | 1997 |
The indomethacin-induced gastric mucosal damage in rats. Effect of gastric acid, acid inhibition, capsaicin-type agents and prostacyclin.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Diterpenes; Epoprostenol; Female; Gastric Acid; Gastric Mucosa; Histamine; Hydrochloric Acid; Indomethacin; Isoproterenol; Laser-Doppler Flowmetry; Male; Microcirculation; Neurotoxins; Pentagastrin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Stomach Ulcer; Vasodilator Agents | 1997 |
Gastric anti-ulcer and cytoprotective effect of l-serine in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Caustics; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Acid; Gastric Mucosa; Hot Temperature; Hydrochloric Acid; Indomethacin; Male; Mucus; Peptic Ulcer; Pylorus; Rats; Rats, Wistar; Serine; Sodium Hydroxide; Solvents; Stereoisomerism; Sulfhydryl Compounds | 1997 |
Studies on the antisecretory, gastric anti-ulcer and cytoprotective properties of glycine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Caustics; Disease Models, Animal; Ethanol; Female; Gastric Acid; Gastric Mucosa; Glycine; Hydrochloric Acid; Indomethacin; Male; Mucus; Pylorus; Rats; Rats, Wistar; Sodium Hydroxide; Solvents; Stomach Ulcer; Sulfhydryl Compounds | 1997 |
Expression of the cyclooxygenase-2 gene in gastric epithelium.
Topics: Animals; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastric Mucosa; Gene Expression; Hydrochloric Acid; Indomethacin; Isoenzymes; Male; Nitrobenzenes; Peroxidases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Time Factors | 1997 |
Prostaglandin E2 and aggressive factors increase the gland luminal pressure in the rat gastric mucosa in vivo.
Topics: Administration, Topical; Animals; Dinoprostone; Ethanol; Gastric Acid; Gastric Mucosa; Gels; Hydrochloric Acid; Indomethacin; Injections, Intra-Arterial; Injections, Intravenous; Male; Mucus; Pressure; Rats; Regional Blood Flow | 1998 |
Carbon dioxide mediates duodenal mucosal alkaline secretion in response to luminal acidity in the anesthetized rat.
Topics: Animals; Carbon Dioxide; Duodenum; Enzyme Inhibitors; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Kinetics; Male; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Sodium Chloride; Time Factors | 1998 |
Involvement of PACAP in acid-induced HCO3- response in rat duodenums.
Topics: Anesthesia; Animals; Bicarbonates; Dinoprostone; Drug Interactions; Duodenum; Hydrochloric Acid; Indomethacin; Male; Neuropeptides; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Receptors, Vasoactive Intestinal Peptide; Vasodilator Agents | 1998 |
Protection by Rhinax in various models of ulceration in rats.
Topics: Animals; Gastric Acid; Gastric Mucins; Hydrochloric Acid; Indomethacin; Ligation; Male; Medicine, Ayurvedic; Models, Biological; Plant Extracts; Pylorus; Rats; Rats, Wistar; Stomach Ulcer | 1998 |
Inducible types of cyclooxygenase and nitric oxide synthase in adaptive cytoprotection in rat stomachs.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cytoprotection; Dinoprostone; Enzyme Induction; Gastric Mucosa; Gastrointestinal Contents; Gene Expression Regulation, Enzymologic; Hydrochloric Acid; Indomethacin; Isoenzymes; Male; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Taurocholic Acid; Transcription, Genetic | 1999 |
Nitric oxide prevents rat duodenal contractions induced by potentially noxious agents.
Topics: Animals; Arginine; Bicarbonates; Capsaicin; Carbon Dioxide; Chromium Radioisotopes; Crosses, Genetic; Duodenum; Edetic Acid; Ethanol; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Intubation, Gastrointestinal; Male; Metabolic Clearance Rate; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 2000 |
Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Furans; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Hydrochloric Acid; Indomethacin; Isoenzymes; Lactones; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; RNA, Messenger; Stomach; Sulfones | 2001 |
Nitric oxide donating compounds inhibit HCl-induced gastric mucosal lesions mainly via prostaglandin.
Topics: 16,16-Dimethylprostaglandin E2; Administration, Oral; Animals; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Stomach Ulcer | 2001 |
Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice.
Topics: Adaptation, Physiological; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cytoprotection; Dinoprostone; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Stomach Ulcer; Sulfonamides; Taurocholic Acid | 2001 |
Role of endogenous nitric oxide and prostaglandin in duodenal bicarbonate response induced by mucosal acidification in rats.
Topics: Animals; Bicarbonates; Dinoprostone; Duodenum; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2001 |
Effects of diacerein on indomethacin-induced gastric ulceration.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dinoprostone; Disease Models, Animal; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Neutrophils; Rats; Reactive Oxygen Species; Stomach Ulcer | 2001 |
Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cytoprotection; Digestive System; Epoprostenol; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Mice; Mice, Knockout; Prostaglandins; Protective Agents; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Regional Blood Flow; Stomach Diseases | 2003 |
Protective effects of polygodial on gastric mucosal lesions induced by necrotizing agents in rats and the possible mechanisms of action.
Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Gastrointestinal Agents; Hydrochloric Acid; Indomethacin; Male; Nitric Oxide; Phytotherapy; Plant Leaves; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Drug; Ruthenium Red; Sesquiterpenes; Stomach Ulcer; Sulfhydryl Compounds; Winteraceae | 2003 |
Evaluation of the antiulcerogenic activity of violacein and its modulation by the inclusion complexation with beta-cyclodextrin.
Topics: Animals; Anti-Ulcer Agents; Cells, Cultured; Chemistry, Pharmaceutical; Cimetidine; Cyclodextrins; Disease Models, Animal; Ethanol; Hepatocytes; Hydrochloric Acid; Indoles; Indomethacin; Lipid Peroxidation; Male; Malondialdehyde; Mice; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological; tert-Butylhydroperoxide | 2003 |
Comparison of the gastroprotective effect of a diterpene lactone isolated from Croton cajucara with its synthetic derivatives.
Topics: Animals; Anti-Ulcer Agents; Croton; Diterpenes; Diterpenes, Clerodane; Ethanol; Hydrochloric Acid; Hypothermia; Indomethacin; Lactones; Male; Mice; Phytotherapy; Plant Bark; Plant Preparations; Stress, Psychological; Structure-Activity Relationship; Ulcer | 2003 |
Prevention of experimentally-induced gastric ulcers in rats by an ethanolic extract of "Parsley" Petroselinum crispum.
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Ethanol; Gastric Mucosa; Hydrochloric Acid; Hypothermia, Induced; Indomethacin; Petroselinum; Plant Extracts; Pylorus; Rats; Rats, Wistar; Sodium Hydroxide; Stomach Ulcer; Time Factors | 2003 |
Role of prostaglandins in maintaining gastric mucus-cell permeability against acid exposure.
Topics: Animals; Cell Line; Cell Membrane Permeability; Diffusion; Dinoprostone; Drug Combinations; Electrophysiology; Epithelial Cells; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Mannitol; Prostaglandins; Rats | 2004 |
Cytotoxic synergy between indomethacin and hydrochloric acid in gastric mucosal cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Gastric Mucosa; Guinea Pigs; Hydrochloric Acid; In Vitro Techniques; Indomethacin; Male | 2004 |
The anti-gastric ulcer effect of Gynostemma pentaphyllum Makino.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Gynostemma; Hydrochloric Acid; Indomethacin; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2004 |
Gastric HCO3- secretion induced by mucosal acidification: different mechanisms depending on acid concentration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bicarbonates; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2005 |
Attenuation of indomethacin- and HCl/ethanol-induced oxidative gastric mucosa damage in rats by kolaviron, a natural biflavonoid of Garcinia kola seed.
Topics: Animals; Catalase; Flavonoids; Garcinia kola; Gastric Mucosa; Glutathione; Hydrochloric Acid; Incidence; Indomethacin; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Preparations; Ranitidine; Rats; Rats, Wistar; Seeds; Stomach Ulcer; Superoxide Dismutase | 2006 |
Role of bile acids, prostaglandins and COX inhibitors in chronic esophagitis in a mouse model.
Topics: Animals; Bile Acids and Salts; Chronic Disease; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Hydrochloric Acid; Indomethacin; Male; Mice; Mice, Inbred Strains; Mucous Membrane; Nitrobenzenes; Pepsin A; Prostaglandins; Radioimmunoassay; Severity of Illness Index; Sulfonamides | 2006 |
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.
Topics: Alkaloids; Ammonia; Animals; Armoracia; Aspirin; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Food Preservatives; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isothiocyanates; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Rats; Rats, Sprague-Dawley; Ruthenium Red; Structure-Activity Relationship | 2007 |
Cytoprotective effects of Bergenia ciliata Sternb, extract on gastric ulcer in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cytoprotection; Ethanol; Hydrochloric Acid; Indomethacin; Ligation; Plant Extracts; Pylorus; Rats; Rats, Wistar; Saxifragaceae; Stomach Ulcer | 2007 |
Anti-ulcerogenic effects of the flavonoid-rich fraction from the extract of Orostachys japonicus in mice.
Topics: Analgesia; Analgesics; Animals; Bethanechol; Crassulaceae; Flavonoids; Gastric Juice; Hydrochloric Acid; Indomethacin; Male; Methanol; Mice; Plant Extracts; Stomach Ulcer; Triterpenes | 2007 |
The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Boswellia; Ethanol; Hot Temperature; Hydrochloric Acid; Indomethacin; Leukotriene Antagonists; Ligation; Male; Phytotherapy; Rats; Rats, Wistar; Stomach Ulcer; Triterpenes | 2008 |
Antiulcerogenic action of ethanolic extract of the resin from Virola surinamensis Warb. (Myristicaceae).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catechin; Cimetidine; Cold Temperature; Ethanol; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Mice; Myristicaceae; Phytotherapy; Plant Extracts; Resins, Plant; Stomach Ulcer; Stress, Physiological | 2009 |
Gastroprotective activity of alkaloid extract and 2-phenylquinoline obtained from the bark of Galipea longiflora Krause (Rutaceae).
Topics: Alkaloids; Animals; Anti-Ulcer Agents; Bethanechol; Dose-Response Relationship, Drug; Ethanol; Hydrochloric Acid; Indomethacin; Mice; Molecular Structure; Plant Bark; Plant Extracts; Quinolines; Rats; Rats, Wistar; Rutaceae; Stomach Ulcer | 2009 |
Anti-ulcerogenic effect and HPLC analysis of the caffeoylquinic acid-rich extract from Ligularia stenocephala.
Topics: Animals; Anti-Ulcer Agents; Asteraceae; Bethanechol; Chromatography, High Pressure Liquid; Ethanol; Gastric Juice; Hydrochloric Acid; Indomethacin; Male; Mice; Mice, Inbred ICR; Peroxynitrous Acid; Plant Extracts; Plant Leaves; Quinic Acid; Species Specificity; Stomach Ulcer | 2010 |
Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Mice; Oxidative Stress; Panax; Saponins; Stomach Ulcer | 2010 |
Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.
Topics: Animals; Anti-Ulcer Agents; Catalase; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Female; Gastric Juice; Gastric Mucosa; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; KATP Channels; Male; Mice; Mucus; Nitric Oxide; Nitric Oxide Synthase; Plant Bark; Plant Extracts; Potassium Channel Blockers; Rats; Rats, Wistar; Reperfusion Injury; Stomach Ulcer; Stress, Physiological; Zanthoxylum | 2011 |
Antiulcerogenic activity of the essential oil of Hyptis martiusii Benth. (Lamiaceae).
Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gas Chromatography-Mass Spectrometry; Gastric Emptying; Gastric Juice; Gastric Mucosa; Gastrointestinal Transit; Hydrochloric Acid; Hydrogen-Ion Concentration; Hyptis; Indomethacin; Male; Medicine, Traditional; Mice; Oils, Volatile; Plant Leaves; Plant Oils; Plant Preparations; Plants, Medicinal; Rats; Rats, Wistar; Stomach Ulcer; Time Factors | 2011 |
The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH.
Topics: Bronchi; Cell Culture Techniques; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Extracellular Fluid; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Indomethacin; Muscle Contraction; Muscle, Smooth; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled; Signal Transduction; Trachea | 2012 |
Antiulcer principle from Zingiber montanum.
Topics: Animals; Anti-Ulcer Agents; Chromatography; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Magnetic Resonance Spectroscopy; Male; Methanol; Mice; Molecular Structure; Phytotherapy; Plants, Medicinal; Rhizome; Sesquiterpenes; Solvents; Stomach Ulcer; Zingiberaceae | 2012 |
Microwave-induced synthesis of alginate-graft-poly(N-isopropylacrylamide) and drug release properties of dual pH- and temperature-responsive beads.
Topics: Acrylamides; Acrylic Resins; Alginates; Drug Delivery Systems; Glucuronic Acid; Glutaral; Hexuronic Acids; Hydrochloric Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogen-Ion Concentration; Imidazoles; Indomethacin; Kinetics; Microwaves; Particle Size; Phase Transition; Polymers; Solutions; Temperature | 2012 |
Cytoprotective and antioxidant effects of the methanol extract of Eremomastax speciosa in rats.
Topics: Acanthaceae; Animals; Anti-Ulcer Agents; Antioxidants; Catalase; Cold Temperature; Ethanol; Gastric Acid; Gastric Mucosa; Glutathione; Hydrochloric Acid; Indomethacin; Ligation; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Plant Extracts; Pylorus; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Superoxide Dismutase | 2014 |
An unusual mulinane diterpenoid from the Chilean plant Azorella trifurcata (Gaertn) Pers.
Topics: Animals; Apiaceae; Diterpenes; Ethanol; Ethylmaleimide; Gastritis; Hydrochloric Acid; Indomethacin; Mice; NG-Nitroarginine Methyl Ester; Plant Extracts; Ruthenium Red | 2014 |
Mechanisms involved in the gastroprotective activity of Celtis iguanaea (Jacq.) Sargent on gastric lesions in mice.
Topics: Acetic Acid; Adrenergic alpha-2 Receptor Antagonists; Animals; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Plant Leaves; Stomach Ulcer; Stress, Physiological; Ulmaceae; Yohimbine | 2014 |
Gastroprotective efficacy and safety evaluation of scoparone derivatives on experimentally induced gastric lesions in rodents.
Topics: Alanine; Animals; Anti-Ulcer Agents; Artemisia; Coumarins; Ethanol; Hydrochloric Acid; Indomethacin; Male; Phytotherapy; Plant Extracts; Quinolones; Rats, Sprague-Dawley; Stomach Ulcer | 2015 |
Gastroprotective bio-guiding study of fruits from Mimusops balata.
Topics: Animals; Anti-Ulcer Agents; Ethanol; Female; Free Radical Scavengers; Fruit; Gastric Mucosa; Glutathione; H(+)-K(+)-Exchanging ATPase; Hydrochloric Acid; Indomethacin; Lipid Peroxides; Mice; Mimusops; Oxidative Stress; Phytotherapy; Plant Extracts; Pylorus; Rats, Wistar; Stomach; Stomach Ulcer | 2015 |
Gastroprotective activity of the resin from Virola oleifera.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Benzothiazoles; Chromatography, Thin Layer; Disease Models, Animal; Ethanol; Flavonoids; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Lethal Dose 50; Male; Mice; Myristicaceae; Phytotherapy; Plant Bark; Plant Extracts; Plants, Medicinal; Polyphenols; Resins, Plant; Solvents; Spectrometry, Mass, Electrospray Ionization; Stomach Ulcer; Sulfonic Acids; Tandem Mass Spectrometry | 2017 |
Gastroprotective and anti-secretory mechanisms of 2-phenylquinoline, an alkaloid isolated from Galipea longiflora.
Topics: Alkaloids; Animals; Anti-Ulcer Agents; Antioxidants; Ethanol; Gastric Acid; Gastric Juice; Gastric Mucosa; Glutathione; Glutathione Transferase; H(+)-K(+)-Exchanging ATPase; Hydrochloric Acid; Indomethacin; Male; Mice; Plant Bark; Plant Extracts; Quinolines; Rats, Wistar; Rutaceae; Stomach Ulcer; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2017 |
Core/shell poly(ethylene oxide)/Eudragit fibers for site-specific release.
Topics: Colon; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Hydrochloric Acid; Indomethacin; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Phenethylamines; Polyethylene Glycols; Polymethacrylic Acids; Technology, Pharmaceutical | 2017 |
Artepillin C, drupanin, aromadendrin-4'-O-methyl-ether and kaempferide from Brazilian green propolis promote gastroprotective action by diversified mode of action.
Topics: Animals; Anti-Ulcer Agents; Cinnamates; Ethanol; Flavonoids; Hydrochloric Acid; Indomethacin; Kaempferols; Male; Mice; Phenylpropionates; Propolis; Stomach Ulcer | 2018 |