hydrazine and levodopa
hydrazine has been researched along with levodopa in 257 studies
Research
Studies (257)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 210 (81.71) | 18.7374 |
| 1990's | 26 (10.12) | 18.2507 |
| 2000's | 11 (4.28) | 29.6817 |
| 2010's | 9 (3.50) | 24.3611 |
| 2020's | 1 (0.39) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Gerlach, J; Lühdorf, K | 1 |
| Walker, E | 1 |
| Dill, RE; Dorris, RL; Phillips-Thonnard, I | 1 |
| Murphy, DL | 1 |
| Tyce, GM; Wong, KL | 1 |
| Leibowitz, M; Lieberman, A | 1 |
| Birket-Smith, E; Dupont, E; Hansen, E; Hyyppä, M; Marttila, R; Mikkelsen, B; Pakkenberg, H; Presthus, J; Rinne, UK | 1 |
| Calne, DB; Gielen, AC; Gillespie, MM; Kartzinel, R; Perlow, M; Sadowsky, DA; TEYCHENNE, P | 1 |
| Lipper, S | 1 |
| Ambrozi, L; Birkmayer, W; Riederer, P; Youdim, MB | 1 |
| Coxon, A; Greenacre, JK; Petrie, A; Reid, JL | 1 |
| Belliard, JP; Boismare, F; Hacpille, L; Le Poncin, M | 2 |
| Borri, P; Borri-Voltattorni, C; Minelli, A | 1 |
| Gilland, O | 1 |
| Castegnaro, E; Pontiroli, AE; Pozza, G; Vettaro, MP; Viberti, GC | 1 |
| Savery, F | 2 |
| Battistin, L; Meneghetti, G; Rigotti, S; Saia, A | 1 |
| Diamond, SG; Markham, CH; Treciokas, LJ | 1 |
| Doyle, AE; Jarrott, B; Louis, WJ; McNeil, JJ; Vajda, FJ | 1 |
| Ohlin, H; Stenberg, P; Wadstein, J | 1 |
| Cotzias, GC; Miller, ST; Papavasiliou, PS; Rosal, VL | 1 |
| Dorner, A; Wajsbort, E; Wajsbort, J | 1 |
| Hokkanen, E; Myllylä, VV; Saarinen, A; Tokola, O | 1 |
| Brambilla, F; Guastalla, A; Maffei, C; Nobile, P; Ponzano, M; Rovere, C; Scarone, S | 1 |
| Carlyle, D; Williams, BO | 1 |
| Del Pesce, M; Di Bella, P; Forastieri, L; Paggi, A; Quattrini, A | 1 |
| Lee, LA; Leebaw, WJ; Woolf, PD | 1 |
| Martin, S | 1 |
| Barbieri, S; Bevilacqua, M; Lanfredini, M; Micossi, P; Nitti, F; Norbiato, G; Raggi, U | 1 |
| Hirayama, K; Kondo, T; Kuruma, I; Narabayashi, H; Yokochi, M | 2 |
| Green, J; Haycook, W; Kilgore, M; Stephens, R | 1 |
| Birkmayer, W; Mentasti, M; Podiwinsky, F; Riederer, P | 1 |
| Barone, DA; Martin, HL | 1 |
| Adamkov, J; Drobný, M; Fundárek, J; Svaleková, A | 1 |
| Bernstein, RM | 1 |
| Bednarczyk, B; Podolec, Z; Szczeklik, A; Vetulani, J | 1 |
| Bender, DA; Earl, CJ; Lees, AJ | 1 |
| Barrionuevo, JA; Cabezas-Cerrato, J; Casanueva, F; Peñalva, A; Vila, T; Villanueva, L | 1 |
| Cassi, E; Massarotti, G; Passaleva, A | 1 |
| Conte, P; Julien, J; Moulinier, J; Reiffers, J | 1 |
| Adlmici, G; Callea, L; Di Monda, V; Fazzari, G | 1 |
| Jotkowitz, S | 1 |
| Hershman, JM; Wingert, TD | 1 |
| Mölsä, P; Rinne, UK | 1 |
| Caraceni, TA; Celano, I; Girotti, F; Parati, E | 1 |
| Kehr, W; Thiede, M; Zimmermann, R | 1 |
| Frohman, LA; Kovathana, N; Nakawatase, C; Szabo, M | 1 |
| Boismare, F; Boquet, J; Le Poncin, M; Lefrançois, J | 1 |
| Brotchi, J; Dresse, A; Gerebtzoff, MA; Lepot, M; Scuvee-Moreau, J | 1 |
| Coscia, CJ; Mitchell, J | 1 |
| Jenner, PG; Jones, MK; Ramsay, ID | 1 |
| Airoldi, L; Watkins, CJ; Wiggins, JF; Wurtman, RJ | 1 |
| Klawans, HL; Kramer, J; Nausieda, PA; Wiener, WJ | 1 |
| Gallamini, A; Magnani, G; Masturzo, P; Murialdo, G; Nizzo, MC | 1 |
| Barkhatova, VP; Markova, ED | 1 |
| Bonnet, K; Friedhoff, AJ; Rosengarten, H | 1 |
| Kuzuya, F; Mori, K; Sakamoto, N; Yoshimine, N | 1 |
| Deze, J; Völler, GW | 1 |
| Gerlach, J | 1 |
| Avery, GS; Brogden, RN; Pinder, RM; Sawyer, PR; Speight, TM | 1 |
| Hanzal, F | 2 |
| Bronaugh, RL; Garver, DL; Rutledge, CO; Wenger, GR | 1 |
| Chouza, C; Gomensoro, JB; Romero, S | 3 |
| Lee, MC; Lippert, DM; Loewenson, RB; Martin, WE; Resch, JA; Tolosa, ES | 1 |
| Aarskog, D; Fevang, FO; Stoa, RF; Thorsen, T | 1 |
| Bianchine, JR | 1 |
| Anderson, F; Joynt, R; Rivera-Calimlim, L; Tandon, D | 1 |
| Hayek, J | 1 |
| Herishanu, Y; Rosenberg, P | 1 |
| Algeri, S; Campanella, G; Cerletti, C; Dolfini, E; Jori, A; Rinaldi, F | 1 |
| Brodt, B; Grimm, W; Schönberger, W; Ziegler, R | 2 |
| Messiha, FS | 1 |
| Agid, Y; Lhermitte, F; Signoret, JL; Studler, JM | 1 |
| Rampton, DS | 1 |
| De la Garza, R; Lombardo, L | 1 |
| Barbeau, A; Roy, M | 1 |
| Lin, JT; Ziegler, DK | 1 |
| Siegfried, J; Zumstein, H | 1 |
| Boismare, F; Hacpille, L; Le Poncin, M | 1 |
| Goodwin, BL; Johnson, RD; Ruthven, CR; Sandler, M | 1 |
| Bass-Verrey, F; Ludin, HP | 1 |
| Goodale, DB; Moore, KE | 1 |
| Carrera, N; Marti-Masso, JF; Martínez-Lage, JM | 2 |
| Augier, D; Dutau, G; Enjaume, P; Ribot, C; Rochiccioli, P | 1 |
| Mizuno, Y; Obayashi, T; Ueki, A; Yoshida, M | 1 |
| Tyce, GM | 1 |
| Londoõ, R | 1 |
| Omoto, T | 1 |
| Kato, N; Murase, Y | 1 |
| Kehr, W | 1 |
| Gabreëls, FJ; Joosten, EM; Keyser, A; Korten, JJ | 1 |
| Jaatoul, N; Kertesz, A; McInnis, W; Paty, DW | 1 |
| Goodgold, A; Jonas, S; Leibowitz, M; Lieberman, A | 1 |
| Baker, AB; Lee, MC; Loewenson, RB; Martin, WE; Resch, JA; Tolosa, ES | 1 |
| Critchley, E | 1 |
| Chapman, B; Feldman, JM | 1 |
| Boismare, F; Boquet, J | 1 |
| Birkmayer, W; Danielczyk, W; Neumayer, E; Riederer, P | 1 |
| Birket-Smith, E | 1 |
| McDowell, FH; Stern, PH; Sweet, RD; Wasterlain, CG | 1 |
| Kishikawa, H; Ohmoto, T | 1 |
| Corsini, GU; Mangoni, A; Marrosu, F; Spissu, A | 1 |
| Rinne, UK; Siirtola, T; Sonninen, V | 1 |
| Cerone, G; Nurzia, A; Pirro, R; Vacca, U | 1 |
| Celesia, GG; Wanamaker, WM | 1 |
| Aldor, T; Gilat, T; Kesten, M; Loewenthal, M; Streifler, M | 1 |
| Nevsímal, O; Roth, B; Vymazal, J | 1 |
| Birket-Smith, E; Dupont, E; Hansen, E; Mikkelsen, B; Pakkenberg, H; Presthus, J; Rautakorpi, I; Riman, E; Rinne, UK | 1 |
| Hildick-Smith, M | 1 |
| Cassel, G; Persson, SA | 1 |
| Goshima, Y; Misu, Y; Nakamura, S; Ohno, K | 1 |
| Blandina, P; Grenader, A; Healy, DP; Huo, TL | 1 |
| Cano, J; Machado, A; Venero, JL | 1 |
| Goshima, Y; Misu, Y; Nakamura, S | 2 |
| Aceves, J; Floran, B; Hernandez, S; Mariscal, S; Martinez-Fong, D; Sierra, A | 1 |
| Ceballos-Baumann, AO; Eckert, W; von Kummer, R; Weicker, H | 1 |
| Blackburn, NA; Boddie, HG; Ellis, CJ; Kendal, BR; MacMahon, DG; Sachdev, D | 1 |
| Archer, T; Fredriksson, A; Sundström, E | 1 |
| Berger, HJ; Horstink, MW; Pasman, JW; van't Hof, MA; Zijlmans, JC | 1 |
| Allievi, C; Bellotti, V; Benedetti, MS; Dordain, G; Dostert, P | 1 |
| Kraus, P; Kuhn, W; Przuntek, H | 1 |
| Rammsayer, T | 1 |
| Rinne, JO; Rinne, UK | 1 |
| Dordain, G; Dostert, P; Strolin Benedetti, M; Vernay, D | 1 |
| Campanella, G; De Michele, G; Filla, A; Mengano, A; Trombetta, L | 1 |
| Liu, DK | 3 |
| Caraceni, T; Lamperti, E; Lorizio, A; Nordera, N | 1 |
| Dichgans, J; Scholz, E | 1 |
| Porter, JC | 1 |
| Achilli, G; Algeri, S; Garattini, S; Perego, C; Ponzio, F; Sacchetti, G | 1 |
| Bohmaker, K; Friedhoff, AJ; Goldstein, M; Meller, E; Namba, Y | 1 |
| Albani, C; Hacisalihzade, SS; Mansour, M | 1 |
| Cossutta, E; Ferrante, C; Pezzoli, G; Scarlato, G; Tesei, S; Zecchinelli, A | 2 |
| Aljanati, R; Caamaño, JL; Chouza, C; de Medina, O; Romero, S; Scaramelli, A | 1 |
| Dupont, E; Hansen, E; Jensen, NO; Mikkelsen, B; Mikkelsen, BO | 2 |
| Stern, G | 1 |
| Mondal, BK; Mondal, KN | 1 |
| Birkmayer, GD; Birkmayer, W | 1 |
| Csanda, E; Takáts, A; Tárczy, M | 1 |
| Da Prada, M; Haefely, WE; Kettler, R; Schaffner, R; Zürcher, G | 1 |
| Kuhn, W; Przuntek, H | 1 |
| Bayer, AJ; Day, JJ; Finucane, P; Pathy, MS | 1 |
| Battegay, R; Gastpar, M; Zmilacher, K | 1 |
| Marion, MH; Marsden, CD; Quinn, NP | 1 |
| Aymard, N; Holzer, J; Rondot, P; Ziegler, M | 2 |
| Erni, W; Held, K | 1 |
| Jenner, P; Malcolm, SL; Marion, MH; Marsden, CD; Quinn, NP; Stocchi, F | 1 |
| Ludin, HP | 1 |
| D'Andrea, G; Durisotti, C; Ferro-Milone, F; Lion, P; Lorizio, A; Nordera, GP | 1 |
| Baas, H; Fischer, PA | 1 |
| Heersema, T; Jansen, EN; Meerwaldt, JD; Speelman, JD; van Manen, J | 1 |
| Lees, AJ; Poewe, WH; Stern, GM | 1 |
| Jansen, EN; Meerwaldt, JD | 1 |
| Rinne, UK | 1 |
| Lees, AJ | 1 |
| Allen, JG; Bird, H; Malcolm, SL; Marion, MH; Marsden, CD; O'Leary, CG; Quinn, NP | 1 |
| Crevoisier, C; Da Prada, M; Hoevels, B; Zürcher, G | 1 |
| Aljanati, R; Caamano, JL; Chouza, C; de Medina, O; Gonzales Panizza, V; Romero, S; Scarmelli, A | 1 |
| Siegfried, J | 1 |
| Jenner, P; Marion, MH; Marsden, CD; Quinn, NP; Stocchi, F | 1 |
| Watanabe, H | 1 |
| Birkmayer, W; Hars, V; Knoll, J; Marton, J; Riederer, P; Youdim, MB | 1 |
| King, TS; Morgan, WW; Steger, RW | 1 |
| Berglund, B; Kaijser, L; Sachs, C | 1 |
| Domenici, L; Fiorentini, A; Maffei, L; Piccolino, M; Trimarchi, C | 1 |
| Yu, HZ | 1 |
| Munro, HN; Roel, LE; Weiss, BF; Wurtman, RJ | 1 |
| Glasgow, GL; Henley, JW; Willoughby, EW | 1 |
| Rondot, P | 1 |
| Braham, J; Sarova-Pinhas, I | 1 |
| Cotzias, GC; Mena, I; Papavasiliou, PS | 1 |
| Kadzielawa, K | 1 |
| Balestreri, R; Bertolini, S; Costa, S; Elicio, N | 1 |
| Eden, E; Nasmyth, PA | 1 |
| Baumann, N; Castaigne, P; Rondot, P; Taberlet, A | 1 |
| Campanella, G; Pennetta, R | 1 |
| Masi, G; Megna, GF; Puca, FM; Specchio, LM | 1 |
| Fermaglich, J | 1 |
| Steinhäusl, H | 1 |
| Andén, NE; Engel, J | 1 |
| Casey, DE; Gerlach, J | 1 |
| Achilli, G; Algeri, S; Cimino, M; Lipartiti, M; Perego, C; Ponzio, F; Vantini, G | 1 |
| Bhagavan, HN; Brin, M | 1 |
| Iadgarov, IS; Kandel', EI | 1 |
| Bondiolotti, GP; Cocchi, D; Locatelli, V; Müller, EE; Parati, EA; Parenti, M; Penalva, A; Picotti, GB | 1 |
| Bitton, V; Globus, M; Hefti, F; Melamed, E | 1 |
| Goldstein, M; Gopinathan, G; Hiesiger, E; Lieberman, AN; Nelson, J; Neophytides, A; Walker, R | 1 |
| Ricaurte, GA; Schuster, CR; Seiden, LS | 1 |
| Gerdes, U; Lehmann, K; Ulm, G | 1 |
| Kamenetskiĭ, VK | 1 |
| Dean, BC; McLellan, DL | 1 |
| Caraceni, T; Cocchi, D; Giovannini, P; Martinez-Campos, A; Müller, EE; Novelli, A | 1 |
| Shum, A; Sole, MJ; Van Loon, GR | 1 |
| Klingler, M | 1 |
| Agnoli, A; Baldassarre, M; D'Urso, R; De Giorgio, G; Falaschi, P; Rocco, A; Ruggieri, S | 1 |
| Passerini, D; Pezzoli, G; Radaelli, F; Scarlato, G | 1 |
| Callingham, BA; Lyles, GA | 2 |
| Fahn, S; Jackson, V; Jiang, D; Reches, A; Wagner, HR | 1 |
| Akpinar, S | 1 |
| Chan, LL; Sinniah, D | 1 |
| Caraceni, T; Giovannini, P; Martinez-Campos, A; Müller, EE; Novelli, A; Parati, E | 1 |
| Demarest, KT; Moore, KE | 1 |
| Alexiuk, NA; Green-Johnson, J; Ryan, E; Vriend, J | 1 |
| Hashiguti, H; Ikeda, T; Maruyama, W; Nakahara, D; Naoi, M | 1 |
| Hashiguti, H; Kaneda, N; Nagatsu, T; Nakahara, D; Sasaoka, T | 1 |
| Goshima, Y; Misu, Y; Miyamae, T; Yue, JL | 1 |
| Goshima, Y; Misu, Y; Miyamae, T; Nakamura, S; Ueda, H; Yue, JL | 1 |
| Alexiuk, NA; Uddin, M; Vriend, J | 1 |
| Frain, O; Guibert, B; Leviel, V; Olivier, V; Pasqualini, C | 1 |
| Arnaiz, CO; Stehouwer, DJ; Taylor, LL; van Hartesveldt, C | 1 |
| López de Pablo, AL; Marco, EJ; Moreno, MJ | 1 |
| Baĭchurina, AZ; Garaev, RS; Semina, II | 1 |
| Hashiguchi, H; Ishida, Y; Ishizuka, Y; Kuwahara, I; Mitsuyama, Y; Nakane, H; Nishimori, T; Todaka, K; Uchimura, D | 1 |
| Ahier, RG; Ashworth, S; Hume, SP; Opacka-Juffry, J | 1 |
| Beiske, A; Fotteler, B; Jorga, KM; Larsen, JP; Moe, B; Schleimer, M; Schmitt, M | 1 |
| Arai, N; Furukawa, N; Goshima, Y; Misu, Y; Miyamae, T | 1 |
| Jackson, M; Jenner, P; Treseder, SA | 1 |
| Jenner, P; Rose, S; Treseder, SA | 1 |
| Arai, N; Fujita, K; Furukawa, N; Goshima, Y; Misu, Y; Miyamae, T; Ohshima, E; Suzuki, F | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Lopez, A; Muñoz, A | 1 |
| Connor, TJ; Kelly, JP; Leonard, BE; Nolan, Y | 1 |
| CAHN, J; HELBECQUE, C; HEROLD, M; JULLIARD, AM; LASJAUNIAS, T | 1 |
| BARRE, N; CAHN, J; HEROLD, M | 1 |
| Bérod, A; Dalmaz, Y; Mamet, J; Perrin, D; Roux, JC; Scarna, H | 1 |
| Fisher, JS; Lipsitz, JR; Minteer, SD; Patil, PB; Smith, JL | 1 |
| Funabashi, T; Goshima, Y; Kimura, F; Kuroiwa, Y; Misu, Y; Shimamura, M; Shimizu, M; Yagami, T | 1 |
| Aceves, J; Cortes, H; Erlij, D; Escartín, E; Florán, B; Florán, L; Rangel, C; Silva, I | 1 |
| Goshima, Y; Matsushita, N; Misu, Y | 1 |
| Edwards, RH; Kanter, E; Kobayashi, K; Krantz, DE; Larsen, KE; Mosharov, EV; Phillips, KA; Schmitz, Y; Sulzer, D; Wilson, K | 1 |
| Mertens, B; Michotte, Y; Sarre, S; Vanderheyden, P | 1 |
| Alachkar, A; Brotchie, JM; Jones, OT | 1 |
| Pruett, BS; Salvatore, MF | 1 |
| Boukherroub, R; Das, MR; Li, M; Szunerits, S; Wang, Q | 1 |
| Georgieva, SG; Kerkerian-Le Goff, L; Khaindrava, VG; Khakimova, GR; Kozina, EA; Krasnov, AN; Kucheryanu, VG; Ugrumov, MV; Vorobyeva, NE | 1 |
| Abe, H; Ebihara, K; Ikarashi, Y; Imamura, S; Ishida, Y; Kase, Y; Koganemaru, G; Mizoguchi, K; Sekiguchi, K; Tabuchi, M | 1 |
| Du, N; Guo, Z; Han, M; Huang, Y; Liu, J; Xu, S | 1 |
| Gao, X; Li, Z; Liu, J; Ren, W; Sun, Y; Tang, H; Wang, F; Zhang, Y; Zhao, QX | 1 |
Reviews
4 review(s) available for hydrazine and levodopa
| Article | Year |
|---|---|
The behavioral toxicity of monoamine oxidase-inhibiting antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior; Behavior, Animal; Dextroamphetamine; Humans; Hydrazines; Iproniazid; Isocarboxazid; Levodopa; Lithium; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Procarbazine; Rats; Tranylcypromine; Tryptophan | 1977 |
Levodopa and decarboxylase inhibitors: a review of their clinical pharmacology and use in the treatment of parkinsonism.
Topics: Benserazide; Binding Sites; Carbidopa; Carboxy-Lyases; Drug Interactions; Humans; Hydrazines; Kinetics; Levodopa; Liver Function Tests; Parkinson Disease | 1976 |
The hydrodynamically balanced system: a novel principle of controlled drug release.
Topics: Administration, Oral; Benserazide; Biological Availability; Capsules; Delayed-Action Preparations; Drug Combinations; Humans; Hydrazines; Levodopa | 1987 |
Drug--vitamin B6 interaction.
Topics: Contraceptives, Oral; Cycloserine; Ethanol; Humans; Hydrazines; Levodopa; Nutritional Requirements; Penicillamine; Pyridoxine; Vitamin B 6 Deficiency | 1983 |
Trials
57 trial(s) available for hydrazine and levodopa
| Article | Year |
|---|---|
The effect of L-dopa on young patients with simple schizophrenia, treated with neuroleptic drugs: a double-blind cross-over trial with Madopar and placebo.
Topics: Adult; Affect; Antipsychotic Agents; Anxiety; Basal Ganglia Diseases; Benserazide; Brief Psychiatric Rating Scale; Clinical Trials as Topic; Drug Combinations; Emotions; Humans; Hydrazines; Levodopa; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Behavior | 1975 |
Comparison of dopa decarboxylase inhibitor (carbidopa) combined with levodopa and levodopa alone on the cardiovascular system of patients with parkinson's disease.
Topics: Adult; Aged; Arrhythmias, Cardiac; Carbidopa; Cardiac Complexes, Premature; Cardiovascular System; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male; Middle Aged; Parkinson Disease; Tachycardia | 1975 |
Levodopa alone and in combination with a peripheral decarboxylase inhibitor benserazide (Madopar) in the treatment of Parkinson's disease: A controlled clinical trial.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Vomiting | 1975 |
Bromocriptine and levodopa (with or without carbidopa) in parkinsonism.
Topics: Aged; Bromocriptine; Carbidopa; Clinical Trials as Topic; Disability Evaluation; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation; Ergolines; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Placebos; Time Factors | 1976 |
Implications of combined treatment with 'Madopar' and L-deprenil in Parkinson's disease. A long-term study.
Topics: Administration, Oral; Aged; Benserazide; Clinical Trials as Topic; Disability Evaluation; Drug Combinations; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrazines; Injections, Intravenous; Levodopa; Male; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenethylamines; Time Factors | 1977 |
Comparison of levodopa with carbidopa or benserazide in parkinsonism.
Topics: Aged; Benserazide; Carbidopa; Consumer Behavior; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
[Levodopa and decarboxylase inhibitors in Parkinson's disease].
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Vomiting | 1977 |
Stimulatory effect of the dopa-decarboxylase inhibitor Ro 4-4602 on prolactin release; inhibition by l-dopa, metergoline, methysergide and 2-Br-alpha-ergocryptine.
Topics: Administration, Oral; Adolescent; Adult; Benserazide; Bromocriptine; Clinical Trials as Topic; Drug Interactions; Ergolines; Female; Humans; Hydrazines; Levodopa; Male; Metergoline; Methysergide; Middle Aged; Pituitary Gland; Pituitary Gland, Anterior; Prolactin; Secretory Rate; Stimulation, Chemical; Time Factors | 1977 |
Amantadine and a fixed combination of levodopa and carbidopa in the treatment of Parkinson's disease.
Topics: Adult; Aged; Amantadine; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Long-term treatment of Parkinson's disease with L-Dopa and Dopa-decarboxylase inhibitor: therapeutic results and side effects.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1978 |
A double-blind comparison of levodopa, Madopa, and Sinemet in Parkinson disease.
Topics: Adult; Benserazide; Carbidopa; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Vomiting | 1978 |
The combined use of L-alpha-methyldopa hydrazine and methyldopa in the treatment of hypertension.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Levodopa; Male; Methyldopa; Middle Aged; Placebos; Time Factors | 1978 |
Effects of apomorphine and apomorphine-L-dopa-carbidopa on alcohol post-intoxication symptoms.
Topics: Adult; Aged; Alcoholic Intoxication; Alcoholism; Apomorphine; Carbidopa; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged | 1978 |
Treatment of parkinsonism with N-n-propyl norapomorphine and levodopa (with or without carbidopa).
Topics: Aged; Apomorphine; Carbidopa; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1978 |
A comparative clinical investigation of the therapeutic effect of levodopa alone and in combination with a decarboxylase inhibitor (carbidopa) in cases of Parkinson's disease.
Topics: Aged; Carbidopa; Clinical Trials as Topic; Drug Combinations; Electrocardiography; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1978 |
Effect of a slow release preparation of levodopa on Parkinson's disease in combination with a peripheral decarboxylase inhibitor.
Topics: Adult; Antiparkinson Agents; Carbidopa; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1978 |
Catecholaminergic drugs in chronic schizophrenia.
Topics: Adult; Apomorphine; Carbidopa; Chronic Disease; Clinical Trials as Topic; Drug Therapy, Combination; Follicle Stimulating Hormone; Growth Hormone; Humans; Hydrazines; Imipramine; Levodopa; Luteinizing Hormone; Male; Middle Aged; Placebos; Schizophrenia, Disorganized; Testosterone | 1979 |
Levodopa/benserazide ('Madopar') combination therapy in elderly patients with parkinsonism.
Topics: Activities of Daily Living; Aged; Benserazide; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1979 |
[Efficacy and side-effects of long term L-dopa therapy in Parkinsonian syndromes (evaluated by CT scan as well) (author's transl)].
Topics: Adult; Benserazide; Brain; Carbidopa; Clinical Trials as Topic; Confusion; Electrocardiography; Electroencephalography; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Stomach Diseases; Tomography, X-Ray Computed | 1979 |
[The combined treatment of Parkinson's disease with L-dopa plus decarboxylase inhibitors (carbidopa, benserazide) (author's transl)].
Topics: Aged; Benserazide; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
Levodopa with benserazide or carbidopa in Parkinson disease.
Topics: Benserazide; Biological Availability; Carbidopa; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
[The clinical experience with the decarboxylase-blocked levodopa (Nacom) in the Parkinsonism patients].
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Effect of CB 154 (2-bromo-alpha-ergocryptine) on paralysis agitans compared with Madopar in a double-blind, cross-over trial.
Topics: Aged; Azides; Benserazide; Bromocriptine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Ergolines; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Psychoses, Substance-Induced | 1976 |
Amantadine and a fixed combination of carbidopa and levodopa in parkinsonism: a preliminary report.
Topics: Aged; Amantadine; Carbidopa; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
[Treatment of Parkinson's syndrome with L-dopa and L-carbidopa (author's transl)].
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Parkinson Disease; Pyridoxine | 1976 |
Madopar versus sinemet. A clinical study on their effectiveness.
Topics: Adult; Aged; Benserazide; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Serine | 1975 |
Alpha methyldopahydrazine as an adjunct to levodopa therapy in Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Placebos; Time Factors | 1975 |
Comparison of dopa decarboxylase inhibitor (carbidopa) combined with levodopa and levodopa alone in Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Mental Disorders; Middle Aged; Movement Disorders; Parkinson Disease | 1975 |
The effects of combining carbidopa with levodopa for Parkinson's disease.
Topics: Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male; Nausea; Parkinson Disease; Vomiting | 1975 |
L-dopa and carbidopa (sinemet) in the management of parkinsonism.
Topics: Aged; Carbidopa; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prognosis | 1975 |
Treatment of "on-off effect" with a dopa decarboxylase inhibitor.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1975 |
Parkinson's disease treated with Sinemet or Madopar. A controlled multicenter trial.
Topics: Aged; Benserazide; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Controlled-release levodopa/benserazide (Madopar HBS): clinical observations and levodopa and dopamine plasma concentrations in fluctuating parkinsonian patients.
Topics: Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Dopamine; Drug Combinations; Female; Follow-Up Studies; Hospitalization; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1990 |
A comparison of the effects of controlled-release levodopa (Madopar CR) with conventional levodopa in late Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Benserazide; Carboxy-Lyases; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Motor Skills; Multicenter Studies as Topic; Neurologic Examination; Parkinson Disease | 1990 |
Is there a common dopaminergic basis of time perception and reaction time?
Topics: Adult; Benserazide; Brain; Clinical Trials as Topic; Dopamine Agents; Double-Blind Method; Drug Combinations; Haloperidol; Humans; Hydrazines; Levodopa; Male; Reaction Time; Receptors, Dopamine; Time Perception | 1989 |
A comparison of Madopar CR and standard Madopar in the treatment of nocturnal and early-morning disability in Parkinson's disease. The U.K. Madopar CR Study Group.
Topics: Activities of Daily Living; Aged; Benserazide; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Randomized Controlled Trials as Topic | 1989 |
A double-blind, cross-over trial with madopar HBS in patients with Parkinson's disease.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary | 1989 |
A combined regimen of subcutaneous lisuride and oral Madopar HBS in Parkinson's disease.
Topics: Administration, Oral; Benserazide; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Drug Tolerance; Ergolines; Humans; Hydrazines; Infusion Pumps; Levodopa; Lisuride; Parkinson Disease; Severity of Illness Index | 1988 |
A controlled release form of madopar in parkinsonian patients with advanced disease and marked fluctuations in motor performance.
Topics: Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Movement; Parkinson Disease | 1988 |
Madopar HBS in fluctuating parkinsonian patients: two-year treatment.
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1988 |
The effect of R-(-)-deprenyl in de novo Parkinson patients on combination therapy with levodopa and decarboxylase inhibitor.
Topics: Benserazide; Clinical Trials as Topic; Disability Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement; Parkinson Disease; Phenethylamines; Selegiline | 1987 |
Bioavailability and acceptability of a dispersible formulation of levodopa-benserazide in parkinsonian patients with and without dysphagia.
Topics: Aged; Aged, 80 and over; Benserazide; Biological Availability; Capsules; Consumer Behavior; Deglutition Disorders; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Random Allocation; Tablets | 1988 |
Open study of Madopar HBS, a new formulation of levodopa with benserazide, in 13 patients with Parkinson's disease and 'on-off' fluctuations.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Clinical trial of Madopar HBS in parkinsonian patients with fluctuating drug response after long-term levodopa therapy.
Topics: Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1987 |
Single-dose studies of a slow-release preparation of levodopa and benserazide (Madopar HBS) in Parkinson's disease.
Topics: Administration, Oral; Adult; Aged; Benserazide; Biological Availability; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Random Allocation | 1987 |
Open clinical study of Madopar HBS.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Infant, Newborn; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Treatment of parkinsonian conditions with a controlled-release form of levodopa--preliminary study.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Preliminary experience with Madopar HBS: clinical observations and plasma levodopa concentrations.
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Open multicenter trial with Madopar HBS in parkinsonian patients. Preliminary assessment after short-term treatment.
Topics: Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1987 |
Clinical and pharmacokinetic observations with Madopar HBS in hospitalized patients with Parkinson's disease and motor fluctuations.
Topics: Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Hospitalization; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
[Controlled release levodopa-benserazide and changes in efficacy during treatment of Parkinson's disease].
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1987 |
Single-dose study of slow release preparation of levodopa and benserazide (Madopar HBS) in Parkinson's disease.
Topics: Administration, Oral; Aged; Benserazide; Clinical Trials as Topic; Delayed-Action Preparations; Disability Evaluation; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Random Allocation | 1987 |
L-alpha-methyldopa hydrazine (Carbidopa) combined with L-dopa in the treatment of Parkinson's disease.
Topics: Aged; Blood Pressure; Carbidopa; Clinical Trials as Topic; Depression, Chemical; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Placebos; Posture; Vomiting | 1974 |
[Experiences in the treatment of Parkinson's disease with a combination drug: L-dopa plus decarboxylase inhibitor (Ro 8-0576)].
Topics: Benserazide; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Combinations; Evaluation Studies as Topic; Gastrointestinal Diseases; Gymnastics; Humans; Hydrazines; Levodopa; Parkinson Disease; Speech Therapy | 1973 |
Sinemet.
Topics: Carbidopa; Clinical Trials as Topic; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1974 |
Report on 45-month treatment of parkinsonism with L-dopa, alone and in association with a decarboxilase inhibitor (Ro 4-4602).
Topics: Adult; Aged; Benserazide; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Tablets | 1974 |
The effect of tolcapone on the pharmacokinetics of benserazide.
Topics: Aged; Antiparkinson Agents; Benserazide; Benzophenones; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Time Factors; Tolcapone; Tyrosine | 1999 |
Other Studies
196 other study(ies) available for hydrazine and levodopa
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Drug therapy for Parkinsonism.
Topics: Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1976 |
A pharmacologic model of Huntington's chorea.
Topics: Animals; Carbachol; Catheterization; Clozapine; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Haloperidol; Huntington Disease; Hydrazines; Levodopa; Male; Phentolamine; Rats; Trifluoperazine; Tyramine | 1976 |
Pyridoxal 5'-phosphate levels in brain after treatments which impair cerebral glucose metabolism.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Benserazide; Brain; Cyclopropanes; Glucose; Hepatectomy; Hydrazines; Levodopa; Male; Monoamine Oxidase Inhibitors; Phenyl Ethers; Pyridoxal Phosphate; Rats | 1979 |
Letter: Psychosis in patient on bromocriptine and levodopa with carbidopa.
Topics: Bromocriptine; Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Schizophrenia, Paranoid | 1976 |
[Effect of L-dopa combined with benserazide on hemodynamics and motor activity in hypoxic rats].
Topics: Animals; Benserazide; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Heart Rate; Hemodynamics; Hydrazines; Hypoxia; Levodopa; Motor Activity; Oxygen; Rats | 1975 |
Interaction of N-(DL-seryl)N'-(2,3,4-trihydroxybenzyl)-hydrazine with L-dopa decarboxylase from pig kidney.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Dopa Decarboxylase; Hydrazines; Kidney; Kinetics; Levodopa; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Swine; Tyrosine | 1977 |
Effects of CNS dopamine augmentation on stimulated prolactin secretion.
Topics: Adult; Carbidopa; Humans; Hydrazines; Insulin; Levodopa; Male; Prolactin; Thyrotropin-Releasing Hormone | 1977 |
Pharmaceutical review: salbutamol - madopar - isocal.
Topics: Albuterol; Australia; Benserazide; Humans; Hydrazines; Levodopa; Lung Diseases; Parenteral Nutrition; Parkinson Disease | 1978 |
Effect of metoclopramide, a dopaminergic inhibitor, on renin and aldosterone in idiopathic edema: possible therapeutic approach with levodopa and carbidopa.
Topics: Adult; Aldosterone; Body Weight; Carbidopa; Edema; Female; Humans; Hydrazines; Levodopa; Metoclopramide; Renin; Sodium | 1979 |
[Comparative studies of L-DOPA alone and combination with a peripheral DOPA decarboxylase inhibitor, HCL-benserazide, on Parkinson's disease-part I: clinical aspects (author's transl)].
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Dopa Decarboxylase; Drug Administration Schedule; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
Electroencephalographic change in Parkinsonian patients treated with levodopa-carbidopa.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Electroencephalography; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
Causes of pseudotumor cerebri and papilledema.
Topics: Aged; Carbidopa; Dose-Response Relationship, Drug; Female; Humans; Hydrazines; Levodopa; Papilledema; Parkinson Disease; Pseudotumor Cerebri | 1979 |
[Comparative studies of L-DOPA alone and combination with a peripheral DOPA decarboxylase inhibitor, benserazide-HCl, on Parkinson's disease--Part II: Pharmacokinetic study (author's transl)].
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Kinetics; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1979 |
[Therapy of rigidity and hypokinesis in old age using Sinemet].
Topics: Aged; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Movement Disorders; Muscle Rigidity; Parkinson Disease, Postencephalitic; Trihexyphenidyl | 1979 |
Reversible haemolytic anaemia after levodopa-carbidopa.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Parkinson Disease | 1979 |
Central dopamine receptors regulate blood eosinophilia in the rat.
Topics: Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Alcohols; Brain; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Eosinophils; Haloperidol; Hydrazines; Hypophysectomy; Leukocyte Count; Levodopa; Male; Phenylthiourea; Rats; Receptors, Dopamine | 1979 |
Niacin depletion in Parkinsonian patients treated with L-dopa, benserazide and carbidopa.
Topics: Adolescent; Adult; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Hydrazines; Levodopa; Male; Micrococcus; Middle Aged; Nicotinamidase; Nicotinic Acids; Parkinson Disease; Tryptophan | 1979 |
[Growth hormone secretion induced by L-Dopa and a dopa decarboxylase inhibitor blocked by free fatty acids].
Topics: Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Drug Synergism; Fatty Acids, Nonesterified; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Pituitary Gland; Secretory Rate | 1979 |
Lupus-like autoimmune syndrome after levodopa and benserazide.
Topics: Autoimmune Diseases; Benserazide; Humans; Hydrazines; Levodopa; Lupus Erythematosus, Systemic; Male; Middle Aged; Syndrome | 1979 |
["Immune type" haemolysis in course of L. dopa-benserazide therapeutic (author's transl)].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Benserazide; Coombs Test; Female; Humans; Hydrazines; Levodopa; Parkinson Disease | 1979 |
[On a muscular dystony case from manganism. Therapeutic clinic considerations (author's transl)].
Topics: Benserazide; Diazepam; Dystonia; Haloperidol; Humans; Hydrazines; Levodopa; Male; Manganese; Middle Aged | 1979 |
Need for uncombined carbidopa to treat parkinsonism.
Topics: Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease | 1978 |
Sinemet and thyroid function in Parkinson disease.
Topics: Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Thyroid Function Tests; Thyroid Gland; Thyrotropin | 1979 |
Bromocriptine alone or associated with L-dopa plus benserazide in Parkinson's disease.
Topics: Aged; Benserazide; Bromocriptine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Methoxytyrosine formation as an indicator of catechol-O-methyltransferase activity in rat liver in vivo.
Topics: Amino Acids; Animals; Carboxy-Lyases; Catechol O-Methyltransferase; Hydrazines; Levodopa; Liver; Male; Rats; Time Factors; Tyrosine | 1977 |
Effect of the dopa decarboxylase inhibitor MK-486 on L-dopa-induced inhibition of prolactin secretion: evidence for CNS participation in the L-dopa effects.
Topics: Adrenal Medulla; Animals; Brain; Carbidopa; Cerebral Cortex; Depression, Chemical; Hydrazines; Hypothalamus; Levodopa; Male; Pituitary Gland, Anterior; Prolactin; Rats | 1977 |
[Improvement with the combination of L-dopa and benserazide of postural dysregulations of the cerebral circulation: preliminary study].
Topics: Benserazide; Cerebrovascular Circulation; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male; Posture | 1977 |
Action of phenytoin, ethosuximide and of the carbidopa-L-dopa association in semi-chronic cobalt-induced epilepsy in the rat.
Topics: Animals; Carbidopa; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Ethosuximide; Hydrazines; Levodopa; Male; Phenytoin; Rats; Seizures | 1977 |
Application of paired-ion high-pressure liquid column chromatography to the analysis of L-3,4-dihydroxyphenylalanine metabolites.
Topics: Carbidopa; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease | 1978 |
The effect of low dose carbidopa/levodopa on prolactin and growth hormone concentrations in patients with breast cancer and in benign breast tumours.
Topics: Adult; Aged; Breast Neoplasms; Carbidopa; Dihydroxyphenylalanine; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Middle Aged; Prolactin; Thyroxine; Time Factors | 1978 |
Effect of pyridoxine on the depletion of tissue pyridoxal phosphate by carbidopa.
Topics: Animals; Brain; Carbidopa; Dopa Decarboxylase; Dopamine; Hydrazines; Hypothalamus; Levodopa; Liver; Male; Muscles; Pyridoxal Phosphate; Pyridoxine; Rats | 1978 |
Paradoxial response to dopaminergic agents in parkinsonism.
Topics: Acetonitriles; Aged; Carbidopa; Ergolines; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Receptors, Dopamine | 1978 |
[Effects of benserazide administration on prolactin secretion].
Topics: Acromegaly; Adult; Benserazide; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Pituitary Gland, Anterior; Prolactin | 1978 |
[Pathogenesis and treatment of torsion dystonia].
Topics: Carbidopa; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Epinephrine; Homovanillic Acid; Humans; Hydrazines; Jews; Levodopa; Norepinephrine; Vanilmandelic Acid | 1978 |
Receptor-cell sensitivity modification (RSM) as a model for pathogenesis and treatment of tardive dyskinesia.
Topics: Animals; Carbidopa; Disease Models, Animal; Drug Combinations; Dyskinesia, Drug-Induced; Hydrazines; Levodopa; Rats; Receptors, Dopamine | 1978 |
[Effect of VB6 on L-DOPA decarboxylase activity in the organs of rats given peripheral L-DOPA decarboxylase inhibitors (author's transl)].
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dopa Decarboxylase; Hydrazines; Levodopa; Male; Pyridoxine; Rats | 1978 |
Effect of carbidopa on the metabolism of L-dopa in the pigtail monkey.
Topics: Animals; Carbidopa; Dopa Decarboxylase; Female; Haplorhini; Homovanillic Acid; Hydrazines; Lactates; Levodopa; Time Factors | 1976 |
[Long-term syndrome in the treatment of parkinsonism with L-dopa and decarboxylase an inhibitor].
Topics: Adult; Benserazide; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Long-Term Care; Male; Middle Aged; Parkinson Disease | 1976 |
The long-term effects of combining carbidopa with levodopa for Parkinson's disease.
Topics: Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Long-Term Care; Male; Parkinson Disease | 1976 |
The effect of L-dopa with and without decarboxylase inhibitor on growth hormone secretion in children with short stature.
Topics: Administration, Oral; Adolescent; Body Height; Carbidopa; Child; Child, Preschool; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Pituitary Gland; Pituitary Gland, Anterior; Secretory Rate | 1977 |
Drug therapy of Parkinsonism dopaminergic drugs.
Topics: Carbidopa; Humans; Hydrazines; Levodopa; Parkinson Disease | 1977 |
The clinical picture and plasma levodopa metabolite profile of parkinsonian nonresponders. Treatment with levodopa and decarboxylase inhibitor.
Topics: Adult; Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
[Treatment of Parkinson's disease with the combination drug L-carbidopa/L-dopa. Report on a 2 years study].
Topics: Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Movement Disorders; Parkinson Disease; Psychoses, Substance-Induced | 1977 |
Effect of L-dopa on polycythemia.
Topics: Aged; Benserazide; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Polycythemia Vera | 1977 |
Correlation of clinical symptoms, HVA and 5-HIAA in csf and plasma L-DOPA in Parkinsonian patients treated with L-DOPA and L-DOPA + RO 4-4602.
Topics: Benserazide; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Time Factors | 1977 |
[Stimulation of the secretion of somatotropin by administration of Nacom (L-dopa and L-carbidopa) in ambulatory patients with retarded growth].
Topics: Adolescent; Ambulatory Care; Carbidopa; Child; Drug Combinations; Growth Disorders; Growth Hormone; Humans; Hydrazines; Levodopa | 1977 |
Possible mechanism of adverse reaction following levodopa plus benserazide treatment.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Benserazide; Drug Interactions; Hydrazines; Levodopa; Liver; Male; Rats; Time Factors | 1977 |
["Beginning and end of dose" dyskinesias caused by L-DOPA].
Topics: Benserazide; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Hypertensive crisis in a patient given sinemet, metoclopramide, and amitriptyline.
Topics: Acute Disease; Amitriptyline; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Levodopa; Metoclopramide; Middle Aged; Parkinson Disease | 1977 |
[Treatment of Parkinson's syndrome with a combination of levodopa and carbidopa].
Topics: Adult; Aged; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Six-year results of treatment with levodopa plus benzerazide in Parkinson's disease.
Topics: Adult; Aged; Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Patient Dropouts; Time Factors | 1976 |
Psychiatric symptoms with initiation of carbidopa-levodopa treatment.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced | 1976 |
Mortality among Parkinson patients treated with L-dopa combined with a decarboxylase inhibitor.
Topics: Adult; Aged; Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Retrospective Studies; Switzerland | 1976 |
Cardiovascular responses to acute hypoxia in dogs pretreated with benserazide and L-DOPA.
Topics: Animals; Benserazide; Blood Gas Analysis; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Hydrazines; Hypoxia; Levodopa; Regional Blood Flow; Respiration; Vascular Resistance | 1976 |
In vivo assessment of decarboxylase inhibition or potentiation: urinary dopamine and L-dopa output after L-dopa administration.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dopamine; Drug Interactions; Humans; Hydrazines; Levodopa; Parkinson Disease; Pyridoxine; Rats | 1976 |
Study of deterioration in long-term treatment of parkinsonism with L-dopa plus decarboxylase inhibitor.
Topics: Benserazide; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1976 |
A comparison of the effects of decarboxylase inhibitors on L-dopa-induced circling behavior and the conversion of dopa to dopamine in the brain.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Brain; Brocresine; Carbidopa; Dopamine; Hydrazines; Levodopa; Male; Methyldopa; Rats; Time Factors | 1976 |
[Carbidopa-levodopa, growth hormone and parkinsonism].
Topics: Aged; Carbidopa; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Pituitary Gland; Stimulation, Chemical | 1976 |
[Hormonal effects of carbidopa-levodopa in normal patients].
Topics: Adult; Blood Glucose; Carbidopa; Evaluation Studies as Topic; Female; Growth Hormone; Humans; Hydrazines; Hydrocortisone; Hypothalamus; Insulin; Levodopa; Male; Stimulation, Chemical | 1976 |
[Attempt at potentiation of the action of L-dopa on the secretion of growth hormone by benserazide, disulfiram and propranolol].
Topics: Adolescent; Benserazide; Child; Disulfiram; Drug Synergism; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Propranolol | 1976 |
[Combined treatment of Parkinsonism with L-dopa and peripheral dopa decarboxylase inhibitors--clinical course of 13 cases and levels of serum/dopa and dopamine].
Topics: Adult; Aged; Benserazide; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
The effect of L-dopa and an inhibitor of peripheral decarboxylation on glucose metabolism in brain.
Topics: Amino Acids; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Glucose; Brain; Brain Chemistry; Drug Interactions; Glucose; Hydrazines; Levodopa; Rats | 1976 |
[5 years of experience in the treatment of parkinsonism with L-dopa and its combination with Ro4-4602].
Topics: Adult; Aged; Benserazide; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
[Treatment of Parkinson's disease with levodopa and a dopa decarboxylase inhibitor].
Topics: Adult; Aged; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Tablets | 1976 |
[Effects and side effects to levodopa in parkinsonism- results of a collaborative study. (5) Combined therapy with a peripheral decarboxylase inhibitor].
Topics: Adult; Aged; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease | 1976 |
A histochemical study on the central effect of monoamine precursors.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Brain Chemistry; Capillaries; Cerebral Ventricles; Dopamine; Drug Combinations; Hydrazines; Levodopa; Male; Median Eminence; Norepinephrine; Rats; Serotonin; Substantia Nigra | 1975 |
Influence of L-3-methoxytyrosine on monoamine synthesis in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Liver; Male; Myocardium; Norepinephrine; Rats; Serotonin; Tryptophan; Tyrosine | 1975 |
Monoamine oxidase inhibitors: nature of their interaction with rabbit pancreatic islets to alter insluin secretion.
Topics: 5-Hydroxytryptophan; Animals; Dopamine; Dose-Response Relationship, Drug; Harmine; Hydrazines; Insulin; Insulin Secretion; Iproniazid; Islets of Langerhans; Levodopa; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Rabbits; Serotonin; Time Factors; Tranylcypromine; Tryptamines | 1975 |
Letter: Levodopa and dopadecarboxylase in treatment of postural hypotension.
Topics: Aged; Benserazide; Blood Pressure; Cerebrovascular Circulation; Dopa Decarboxylase; Drug Combinations; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male | 1975 |
Dopaminergic supersensitivity in parkinsonism.
Topics: Aged; Benzyl Compounds; Brain; Brain Chemistry; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Nerve Degeneration; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Serotonin; Tryptophan; Tyrosine | 1975 |
Abnormal involuntary movements in relation to anticholinergics and levodopa therapy.
Topics: Benserazide; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Movement Disorders; Parasympatholytics; Parkinson Disease | 1975 |
L-dopa therapy combined with peripheral decarboxylase inhibitor (MK-486) in Parkinsonism.
Topics: Adult; Aged; Animals; Carbidopa; Carboxy-Lyases; Cats; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Injections, Intraperitoneal; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1975 |
[Treatment of Parkinson's syndromes by a combination of levodopa with decarboxylase inhibitors].
Topics: Adult; Aged; Carbidopa; Carboxy-Lyases; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1975 |
Reduction of hypoxia-induced disturbances by previous treatment with benserazide and L-dopa in rats.
Topics: Animals; Benserazide; Brain Chemistry; Carbon Dioxide; Cerebrovascular Circulation; Dopamine; Female; Hydrazines; Hypoxia; Levodopa; Motor Activity; Norepinephrine; Oxygen; Rats | 1975 |
Treatment of Sydenham's chorea with a combination of L-dopa and a peripheral dopa decarboxylase inhibitor.
Topics: Acute Disease; Adolescent; Carbidopa; Chorea; Drug Therapy, Combination; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Recurrence | 1975 |
Urinary excretion of monoamines and their metabolites in patients with Parkinson's disease. Response to long-term treatment with levodopa alone or in combination with a dopa decarboxylase inhibitor and clinical correlations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Benserazide; Biogenic Amines; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Metanephrine; Middle Aged; Normetanephrine; Parkinson Disease; Tyramine; Vanilmandelic Acid | 1975 |
[Effect of carbidopa and L-dopa combination on the secretion of growth hormone in normal subjects and in patients with Parkinsonism].
Topics: Carbidopa; Growth Hormone; Humans; Hydrazines; Levodopa; Parkinson Disease; Pituitary Gland; Stimulation, Chemical | 1975 |
L-dopa-carbidopa: combined therapy for the treatment of Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Liver function and gastric acid secretion in parkinsonian patients under prolonged treatment with L-dopa and a peripheral decarboxylase inhibitor.
Topics: Aged; Benserazide; Biopsy; Drug Combinations; Gastric Juice; Humans; Hydrazines; Levodopa; Liver; Liver Function Tests; Male; Middle Aged | 1976 |
[Experiences in the treatment of Parkinsonism using a combination of L-dopa and alpha-methyldopa-hydrazine].
Topics: Adult; Aged; Drug Combinations; Drug Evaluation; Drug Synergism; Humans; Hydrazines; Levodopa; Methyldopa; Middle Aged; Parkinson Disease | 1976 |
Letter: Alternatives to levodopa.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease | 1976 |
[HGH secretion after oral application of L-dopa and L-carbidopa (author's transl)].
Topics: Administration, Oral; Adolescent; Carbidopa; Child; Growth Hormone; Humans; Hydrazines; Levodopa; Time Factors | 1976 |
Effects of acute lethal cyanide intoxication on central dopaminergic pathways.
Topics: Acute Disease; Animals; Brain; Dopamine; Hydrazines; Levodopa; Male; Poisoning; Rats; Rats, Inbred Strains; Sodium Cyanide | 1992 |
Picomolar concentrations of L-dopa stereoselectively potentiate activities of presynaptic beta-adrenoceptors to facilitate the release of endogenous noradrenaline from rat hypothalamic slices.
Topics: Animals; Cocaine; Electric Stimulation; Hydrazines; Hypothalamus; In Vitro Techniques; Isoproterenol; Levodopa; Male; Norepinephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stereoisomerism | 1991 |
Prostaglandin E2 production in rat IMCD cells. II. Possible role for locally formed dopamine.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Carbidopa; Cells, Cultured; Dinoprostone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Hydrazines; Kidney Medulla; Kidney Tubules, Collecting; Levodopa; Rats; Tyrosine 3-Monooxygenase | 1991 |
Age effects on monoamine turnover of the rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydrazines; In Vitro Techniques; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra | 1991 |
L-dihydroxyphenylalanine methyl ester is a potent competitive antagonist of the L-dihydroxyphenylalanine-induced facilitation of the evoked release of endogenous norepinephrine from rat hypothalamic slices.
Topics: Animals; Binding, Competitive; Carbidopa; Cocaine; Hydrazines; Hypothalamus; In Vitro Techniques; Levodopa; Norepinephrine; Propranolol; Rats; Structure-Activity Relationship; Sulpiride | 1991 |
L-dopa stimulates the release of [3H]gamma-aminobutyric acid in the basal ganglia of 6-hydroxydopamine lesioned rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Basal Ganglia; Benzazepines; Brain Chemistry; Dopamine Antagonists; gamma-Aminobutyric Acid; Hydrazines; Hydroxydopamines; In Vitro Techniques; Levodopa; Male; Nerve Degeneration; Oxidopamine; Potassium; Rats; Rats, Inbred Strains; Sulpiride; Sympathectomy, Chemical | 1991 |
L-dopa facilitates the release of endogenous norepinephrine and dopamine via presynaptic beta 1- and beta 2-adrenoceptors under essentially complete inhibition of L-aromatic amino acid decarboxylase in rat hypothalamic slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic beta-Antagonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dopamine; Electric Stimulation; Hydrazines; Hypothalamus; In Vitro Techniques; Kinetics; Levodopa; Male; Norepinephrine; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1990 |
Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Body Weight; Corpus Striatum; Disease Models, Animal; Dopamine; Hydrazines; Levodopa; Male; Methyltyrosines; Mice; Mice, Inbred C57BL; Motor Activity; Parkinson Disease, Secondary; Receptors, Dopamine; Stereotyped Behavior | 1990 |
Severity of Parkinson's disease is a risk factor for peak-dose dyskinesia.
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Carboxy-Lyases; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Hydrazines; Levodopa; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease | 1990 |
Biosynthesis of salsolinol, a tetrahydroisoquinoline alkaloid, in healthy subjects.
Topics: Adult; Benserazide; Dopamine; Drug Combinations; Female; Humans; Hydrazines; Isoquinolines; Levodopa; Male; Stereoisomerism | 1990 |
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPG, HIAA and HVA levels in the cerebrospinal fluid.
Topics: Benserazide; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Glycols; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Motor Activity; Parkinson Disease; Phenethylamines; Selegiline | 1989 |
Treatment of early Parkinson's disease with controlled-release levodopa preparations.
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease | 1989 |
Enantiomeric composition of urinary salsolinol in parkinsonian patients after Madopar.
Topics: Aged; Aged, 80 and over; Benserazide; Drug Combinations; Female; Humans; Hydrazines; Isoquinolines; Levodopa; Male; Middle Aged; Parkinson Disease; Stereoisomerism | 1989 |
[The concentration of homovanillic acid and leucine-enkephalin in the lumbar CSF of patients with Parkinson's disease before and after madopar treatment].
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Drug Combinations; Enkephalin, Leucine; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1989 |
Madopar HBS and the decompensated phase of Parkinson disease.
Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary | 1989 |
Treatment of drug-induced exogenous psychosis in parkinsonism with clozapine and fluperlapine.
Topics: Aged; Antipsychotic Agents; Benserazide; Bromocriptine; Clozapine; Delusions; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hallucinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan | 1985 |
In situ activity and phosphorylation of tyrosine hydroxylase in the median eminence.
Topics: Animals; Female; Hydrazines; Kinetics; Levodopa; Median Eminence; Phosphorylation; Rats; Tyrosine 3-Monooxygenase; Veratridine | 1986 |
Amineptine: its effect on the dopaminergic system of rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Corpus Striatum; Dibenzocycloheptenes; Dopamine; Hydrazines; Levodopa; Limbic System; Male; Pargyline; Rats | 1986 |
Relationship between receptor occupancy and response at striatal dopamine autoreceptors.
Topics: 4-Butyrolactone; Adrenergic alpha-Antagonists; Animals; Apomorphine; Corpus Striatum; Dihydroxyphenylalanine; Homeostasis; Hydrazines; Levodopa; Male; Piperidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1987 |
Optimization of symptomatic therapy in Parkinson's disease.
Topics: Benserazide; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Computer-Assisted; Humans; Hydrazines; Levodopa; Models, Biological; Parkinson Disease; Reaction Time; Therapy, Computer-Assisted | 1989 |
[An open study of a new formulation of the levodopa and benserazide combination in the treatment of fluctuations of motor performance in patients with Parkinson's disease].
Topics: Aged; Benserazide; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1988 |
MPTP: clinical implications.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Basal Ganglia; Benserazide; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenethylamines; Pyridines; Selegiline | 1986 |
Parkinson's disease in the elderly: a long-term efficacy study of levodopa/benserazide combination therapy.
Topics: Aged; Aged, 80 and over; Benserazide; Bromocriptine; Confusion; Drug Combinations; Dyskinesia, Drug-Induced; Female; Humans; Hydrazines; Levodopa; Long-Term Care; Male; Middle Aged; Parkinson Disease | 1986 |
Effect of (-)deprenyl in long-term treatment of Parkinson's disease. A 10-years experience.
Topics: Benserazide; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenethylamines; Retrospective Studies; Selegiline; Time Factors | 1986 |
(-)Deprenyl in the treatment of decompensated Parkinson's disease.
Topics: Benserazide; Drug Combinations; Humans; Hydrazines; Levodopa; Movement Disorders; Parkinson Disease; Phenethylamines; Selegiline | 1986 |
Inhibition of decarboxylase and levels of dopa and 3-O-methyldopa: a comparative study of benserazide versus carbidopa in rodents and of Madopar standard versus Madopar HBS in volunteers.
Topics: Administration, Oral; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Carbidopa; Delayed-Action Preparations; Dihydroxyphenylalanine; Dogs; Dopa Decarboxylase; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrazines; Kidney; Levodopa; Liver; Male; Mice; Rats; Time Factors; Tyrosine | 1987 |
L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression.
Topics: 5-Hydroxytryptophan; Adult; Aged; Benserazide; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Psychological Tests; Retrospective Studies | 1988 |
Madopar HBS in Parkinson patients with nocturnal akinesia.
Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1988 |
Madopar HBS. International workshop on the 'on-off-phenomenon in Parkinson's disease. New possibilities for its management. Agno, November 14-16, 1985.
Topics: Benserazide; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1987 |
Madopar HBS in the long-term treatment of parkinsonian patients with fluctuations in disability.
Topics: Aged; Benserazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Time Factors | 1987 |
A sustained-release formulation of L-dopa (Madopar HBS) in the treatment of nocturnal and early-morning disabilities in Parkinson's disease.
Topics: Benserazide; Circadian Rhythm; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Single-dose pharmacokinetics of Madopar HBS in patients and effect of food and antacid on the absorption of Madopar HBS in volunteers.
Topics: Adult; Antacids; Benserazide; Biological Availability; Delayed-Action Preparations; Drug Combinations; Eating; Gastric Mucosa; Humans; Hydrazines; Levodopa; Middle Aged; Stomach; Tyrosine | 1987 |
Bioavailability of L-dopa after Madopar HBS administration in healthy volunteers.
Topics: Administration, Oral; Adult; Benserazide; Biological Availability; Capsules; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrazines; Levodopa; Male; Middle Aged | 1987 |
Substitution of standard Madopar by Madopar HBS in parkinsonians with fluctuations.
Topics: Aged; Aged, 80 and over; Benserazide; Biological Availability; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Madopar HBS: slow-release levodopa and benserazide in parkinsonian patients presenting marked fluctuations in symptoms on standard L-dopa treatment.
Topics: Adult; Aged; Benserazide; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Therapeutic value of Madopar HBS: judgment after 2 years experience.
Topics: Adult; Aged; Aged, 80 and over; Benserazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1987 |
Simple method for evaluation of stimulatory effect of drugs on presynaptic dopamine receptors in mice.
Topics: Animals; Apomorphine; Haloperidol; Hydrazines; Hydroxydopamines; Levodopa; Male; Mice; Mice, Inbred Strains; Oxidopamine; Receptors, Dopamine | 1985 |
Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study.
Topics: Adult; Aged; Benserazide; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Life Expectancy; Longitudinal Studies; Male; Middle Aged; Models, Biological; Phenethylamines; Retrospective Studies; Selegiline | 1985 |
Effect of hypophysectomy and subsequent prolactin administration on hypothalamic 5-hydroxytryptamine synthesis in ovariectomized rats.
Topics: Animals; Apomorphine; Castration; Female; Hydrazines; Hypophysectomy; Hypothalamus; Levodopa; Median Eminence; Prolactin; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Autonomic cardiovascular responses in parkinsonism: effect of levodopa with dopa-decarboxylase inhibition.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Autonomic Nervous System; Benserazide; Blood Pressure; Carbidopa; Drug Therapy, Combination; Female; Heart; Heart Rate; Humans; Hydrazines; Levodopa; Male; Middle Aged; Muscle Contraction; Parkinson Disease | 1985 |
Dopaminergic drugs improve human visual contrast sensitivity.
Topics: Adult; Benserazide; Form Perception; Humans; Hydrazines; Levodopa; Nomifensine; Pattern Recognition, Visual | 1985 |
[Clinical significance of cramps of the lower extremities in patients with parkinsonism].
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Leg; Levodopa; Male; Middle Aged; Muscle Cramp; Parkinson Disease | 1985 |
The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbon Radioisotopes; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Enzyme Inhibitors; Hydrazines; Leucine; Levodopa; Lysine; Male; Methyldopa; Nerve Tissue Proteins; Norepinephrine; Polyribosomes; Rats; S-Adenosylmethionine; Time Factors | 1974 |
[Decarboxylase inhibitors combined with L-dopa in the treatment of Parkinson's disease].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Benzyl Compounds; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenols | 1974 |
[Treatment of parkinsonism by L-dopa and dopa-decarboxylase inhibitor in a single tablet].
Topics: Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1974 |
Short- and long-term approaches to the "on-off" phenomenon.
Topics: Apomorphine; Carbidopa; Dietary Proteins; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Movement Disorders; Parkinson Disease; Time Factors | 1974 |
Dopamine receptor in the reward system of the rat.
Topics: Amantadine; Animals; Apomorphine; Benzyl Compounds; Cortical Synchronization; Desipramine; Dihydroxyphenylalanine; Dopamine; Electrodes, Implanted; Electroencephalography; Haloperidol; Hydrazines; Hypothalamus; Levodopa; Male; Rats; Receptors, Drug; Reward; Self Stimulation; Time Factors | 1974 |
[Action of a peripheral inhibitor of dopa-decarboxylase on the inhibition by L-DOPA of the hypothalamo-hypophyseo-adrenocortical system in man].
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Female; Humans; Hydrazines; Hydrocortisone; Hypothalamo-Hypophyseal System; Levodopa; Male; Middle Aged; Pituitary-Adrenal Function Tests | 1974 |
The cardiovascular effects of L-dopa in the pithed rat.
Topics: Animals; Antimetabolites; Aorta, Thoracic; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Blood Pressure; Dopamine; Heart; Hydrazines; In Vitro Techniques; Levodopa; Male; Norepinephrine; Perfusion; Rats; Thiocarbamates; Time Factors; Tyramine; Venous Pressure | 1974 |
[Variation in the pharmacologic affects of decarboxylase inhibitor in variable doses in man].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood-Brain Barrier; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease, Secondary; Time Factors | 1974 |
[The association of L-DOPA and Ro 4-4602 in the treatment of Parkinson's disease (author's transl)].
Topics: Benserazide; Drug Combinations; Drug Evaluation; Humans; Hydrazines; Levodopa; Parkinson Disease | 1974 |
[Psychological changes in parkinsonian patients during L-DOPA, amantidine, and L-DOPA + IDC treatment (author's transl)].
Topics: Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Mental Processes; Parkinson Disease; Psychological Tests | 1974 |
Treatment of Parkinson's disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa.
Topics: Aged; Carbidopa; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1974 |
Effect of L-DOPA and analogues on central dopamine and noradrenaline mechanisms.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Apomorphine; Brain Chemistry; Clonidine; Corpus Striatum; Dopamine; Hydrazines; Levodopa; Methyldopa; Methyltyrosines; Movement; Nialamide; Norepinephrine; Octopamine; Rats; Receptors, Drug; Reflex; Reserpine; Spinal Cord; Stimulation, Chemical; Tyramine; Tyrosine | 1974 |
Dopamine agonists in clinical research for new tardive dyskinesia treatments.
Topics: Adult; Aged; Antipsychotic Agents; Apomorphine; Benserazide; Carbidopa; Dopamine; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Hydrazines; Levodopa; Middle Aged; Synaptic Transmission | 1983 |
In vivo and in vitro evidence of dopaminergic system down regulation induced by chronic L-DOPA.
Topics: Animals; Apomorphine; Benserazide; Binding Sites; Cell Membrane; Corpus Striatum; Dopamine; Hydrazines; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes; Tyrosine 3-Monooxygenase | 1984 |
[Combined (surgical and drug) therapy of parkinsonism].
Topics: Benserazide; Catecholamines; Combined Modality Therapy; Diencephalon; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease; Stereotaxic Techniques | 1984 |
Mechanisms involved in the prolactin-releasing effect of benserazide.
Topics: Animals; Benserazide; Binding, Competitive; Dopamine; Female; Hydrazines; In Vitro Techniques; Levodopa; Male; Median Eminence; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1984 |
Suppression of L-dopa-induced circling in rats with nigral lesions by blockade of central dopa-decarboxylase: implications for mechanism of action of L-dopa in parkinsonism.
Topics: Animals; Behavior, Animal; Corpus Striatum; Dopa Decarboxylase; Dopamine; Dopamine Antagonists; Hydrazines; Levodopa; Male; Parkinson Disease; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra | 1984 |
Combined use of benserazide and carbidopa in Parkinson's disease.
Topics: Adult; Aged; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Outcome and Process Assessment, Health Care; Parkinson Disease | 1984 |
Increased dopamine metabolism in the rat neostriatum after toxic doses of d-methylamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dopamine; Hydrazines; Kinetics; Levodopa; Male; Methamphetamine; Putamen; Rats; Rats, Inbred Strains | 1983 |
Response to Sinemet 25/100 in Parkinson's disease.
Topics: Aged; Benserazide; Body Weight; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Sex Factors | 1984 |
[Treatment of patients with vascular parkinsonism with the preparations nakom and madopar].
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease, Secondary | 1984 |
[Madopar in the treatment of paralysis agitans: II. TRH activation test, EMG examination and HVA level in cerebrospinal fluid before and after treatment].
Topics: Aged; Benserazide; Drug Combinations; Electromyography; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Thyrotropin; Thyrotropin-Releasing Hormone | 1980 |
Improved control of brittle Parkinsonism by separate administration of levodopa and benserazide.
Topics: Benserazide; Drug Administration Schedule; Female; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Time Factors | 1982 |
Thyrotrophin and prolactin responses to thyrotrophin-releasing hormone in patients with Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 1982 |
Simultaneous measurement of 5-hydroxytryptophan and L-dihydroxyphenylalanine by high-performance liquid chromatography with electrochemical detection. Measurement of serotonin and catecholamine turnover in discrete brain regions.
Topics: 5-Hydroxytryptophan; Animals; Benzyl Alcohols; Brain; Catecholamines; Chromatography, High Pressure Liquid; Hydrazines; Kinetics; Levodopa; Male; Microchemistry; Rats; Rats, Inbred Strains; Serotonin | 1982 |
A glimpse into Roche research: antiparkinson treatment.
Topics: Antiparkinson Agents; Benserazide; Drug Combinations; Drug Industry; History, 20th Century; Humans; Hydrazines; Levodopa; Male; Switzerland | 1982 |
Prolactin response to acute administration of different L-dopa plus decarboxylase inhibitors in Parkinson's disease.
Topics: Aged; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Rats | 1982 |
Acute non-haemolytic anemia after short administration of L Dopa plus Benserazide.
Topics: Acute Disease; Aged; Anemia; Antiparkinson Agents; Benserazide; Humans; Hydrazines; Levodopa; Male | 1982 |
In vitro and in vivo inhibition by benserazide of clorgyline-resistant amine oxidases in rat cardiovascular tissues.
Topics: Amine Oxidase (Copper-Containing); Animals; Benserazide; Cardiovascular System; Clorgyline; Drug Resistance; Hydrazines; In Vitro Techniques; Kinetics; Levodopa; Male; Monoamine Oxidase; Oxidoreductases Acting on CH-NH Group Donors; Propylamines; Rats; Rats, Inbred Strains | 1982 |
The effect of chronic L-dopa administration on supersensitive pre- and postsynaptic dopaminergic receptors in rat brain.
Topics: Animals; Brain; Haloperidol; Hydrazines; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1982 |
Treatment of restless legs syndrome with levodopa plus benserazide.
Topics: Adult; Benserazide; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Restless Legs Syndrome | 1982 |
L-dopa and benserazide in the treatment of acute hepatic encephalopathy in infancy.
Topics: Acute Disease; Benserazide; Female; Hepatic Encephalopathy; Humans; Hydrazines; Infant; Levodopa | 1980 |
Growth hormone and prolactin stimulation by Madopar in Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Drug Combinations; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Lisuride; Male; Middle Aged; Parkinson Disease; Prolactin; Receptors, Dopamine | 1981 |
The influence of benserazide on changes in monoamine oxidase activity in some rat tissues following treatment with L-DOPA.
Topics: Animals; Benserazide; Benzylamines; Growth; Hydrazines; Kidney; Kinetics; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Rats; Rats, Inbred Strains; Serotonin | 1980 |
Accumulation of L-dopa in the median eminence: an index of tuberoinfundibular dopaminergic nerve activity.
Topics: Animals; Benzyl Alcohols; Corpus Striatum; Dopamine; Estradiol; Haloperidol; Hydrazines; Hypophysectomy; Hypothalamo-Hypophyseal System; Kinetics; Levodopa; Male; Median Eminence; Rats | 1980 |
[Madopar in the treatment of paralysis agitans. I. Therapeutic efficacy and side-effects in 56 cases (author's transl)].
Topics: Adult; Benserazide; Electrocardiography; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease | 1980 |
Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Biogenic Monoamines; Caudate Nucleus; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Homovanillic Acid; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Mice; Mice, Inbred BALB C; Seizures; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
Simultaneous determination of in vivo hydroxylation of tyrosine and tryptophan in rat striatum by microdialysis-HPLC: relationship between dopamine and serotonin biosynthesis.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1993 |
Normalization of tyrosine hydroxylase activity in vivo in the striatum of transgenic mice carrying human tyrosine hydroxylase gene: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Humans; Hydrazines; Levodopa; Mice; Mice, Transgenic; Microdialysis; RNA Probes; Tyrosine 3-Monooxygenase | 1993 |
Evidence for L-dopa relevant to modulation of sympathetic activity in the rostral ventrolateral medulla of rats.
Topics: alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Heart Rate; Hydrazines; Levodopa; Medulla Oblongata; Methyltyrosines; Microdialysis; Microinjections; Oxidopamine; Rats; Rats, Wistar; Sympathetic Nervous System; Tyrosine 3-Monooxygenase | 1993 |
Non-effective dose of exogenously applied L-dopa itself stereoselectively potentiates postsynaptic D2 receptor-mediated locomotor activities of conscious rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Desipramine; Dopamine Agents; Ergolines; Hydrazines; Injections, Intraventricular; Levodopa; Male; Microdialysis; Motor Activity; Nerve Fibers; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereoisomerism | 1994 |
Melatonin increases the in situ activity of tyrosine hydroxylase in the mediobasal hypothalamus of male Syrian hamsters.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aromatic Amino Acid Decarboxylase Inhibitors; Cricetinae; Enzyme Inhibitors; Hydrazines; Hypothalamus, Middle; Levodopa; Male; Median Eminence; Melatonin; Mesocricetus; Reference Values; Time Factors; Tyrosine 3-Monooxygenase | 1996 |
Rapid stimulation of striatal dopamine synthesis by estradiol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Dopamine; Enzyme Inhibitors; Estradiol; Female; Hydrazines; Levodopa; Ovariectomy; Rats | 1996 |
An aromatic L-amino acid decarboxylase inhibitor blocks L-dopa-induced air-stepping in neonatal rats.
Topics: Animals; Animals, Newborn; Aromatic Amino Acid Decarboxylase Inhibitors; Enzyme Inhibitors; Hindlimb Suspension; Hydrazines; Levodopa; Motor Activity; Rats; Rats, Sprague-Dawley; Reaction Time | 1996 |
In vivo tryptophan hydroxylase activity in rat major cerebral arteries is decreased by dorsal raphe nucleus lesions.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Aorta; Aromatic Amino Acid Decarboxylase Inhibitors; Cerebral Arteries; Corpus Striatum; Electrocoagulation; Enzyme Inhibitors; Fenclonine; Hippocampus; Hydrazines; Hypothalamus; Levodopa; Male; Methyltyrosines; Norepinephrine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Tryptophan Hydroxylase | 1996 |
[The effect on central dopaminergic structures of various hydrazides of phosphorylated carbonic acids and diaziridines].
Topics: Acetates; Animals; Apomorphine; Body Temperature; Catalepsy; Dopamine Agents; Drug Interactions; Haloperidol; Hydrazines; Levodopa; Mice; Stereotyped Behavior | 1996 |
Serotonergic activity in the rat striatum after intrastriatal transplantation of fetal nigra as measured by microdialysis.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Enzyme Inhibitors; Female; Fetal Tissue Transplantation; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Microdialysis; Oxidopamine; Rats; Rats, Wistar; Serotonin; Substantia Nigra; Transplantation, Heterotopic | 1998 |
Modulatory effects of L-DOPA on D2 dopamine receptors in rat striatum, measured using in vivo microdialysis and PET.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carbon Radioisotopes; Corpus Striatum; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Globus Pallidus; Hydrazines; Kinetics; Levodopa; Male; Microdialysis; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Salicylamides; Time Factors; Tomography, Emission-Computed | 1998 |
[Is endogenously released DOPA itself an upstream factor for increase in glutamate release and delayed neuronal cell death induced by transient ischemia in rats?].
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Cell Death; Corpus Striatum; Dihydroxyphenylalanine; Glutamic Acid; Hippocampus; Hydrazines; Ischemic Attack, Transient; Levodopa; Male; Rats; Rats, Wistar | 1998 |
The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Callithrix; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrazines; Levodopa; Male; Motor Activity; Quinolones; Quinpirole; Thiophenes; Tyrosine | 2000 |
The central aromatic amino acid DOPA decarboxylase inhibitor, NSD-1015, does not inhibit L-DOPA-induced circling in unilateral 6-OHDA-lesioned-rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Biogenic Monoamines; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Combinations; Enzyme Inhibitors; Haloperidol; Homovanillic Acid; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine | 2001 |
Endogenously released DOPA is a causal factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in rat striata.
Topics: Animals; Cell Death; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Enzyme Inhibitors; Glutamic Acid; Hydrazines; Ischemic Attack, Transient; Levodopa; Male; Neurons; Rats; Rats, Wistar; Time Factors | 2001 |
Mechanisms of the effects of exogenous levodopa on the dopamine-denervated striatum.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Hydrazines; Levodopa; Motor Activity; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin | 2001 |
Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Enzyme Inhibitors; Escherichia coli; Frontal Lobe; Hydrazines; Levodopa; Lipopolysaccharides; Male; Mesencephalon; Organ Specificity; Rats; Rats, Sprague-Dawley; Time Factors; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2000 |
[Action of some inhibitors of L-DOPA decarboxylase on the duration of barbiturate narcosis in the mouse].
Topics: Animals; Barbiturates; Cinnamates; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrazines; Hydroxylamines; Levodopa; Mice; Pentobarbital; Quinolizines; Stupor | 1962 |
[Action of different inhibitors of L-DOPA 5 HTP decarboxylase on insulin hypoglycemia in the rat].
Topics: 5-Hydroxytryptophan; Animals; Antihypertensive Agents; Antimetabolites; Cinnamates; Dopa Decarboxylase; Hydrazines; Hyperinsulinism; Hypoglycemia; Insulins; Levodopa; Rats; Seizures; Tremor | 1963 |
Long-term prenatal hypoxia alters maturation of brain catecholaminergic systems and motor behavior in rats.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Catecholamines; Enzyme Inhibitors; Exploratory Behavior; Female; Hydrazines; Hypoxia; Levodopa; Male; Motor Activity; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Time; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Possibility of autocrine beta-adrenergic signaling in C2C12 myotubes.
Topics: Adrenergic beta-Antagonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autocrine Communication; Biological Transport, Active; Cell Line; Cyclic AMP; Dopa Decarboxylase; Dopamine; Dopamine Agents; Glucose; Hydrazines; Hypoglycemic Agents; Insulin; Levodopa; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts, Skeletal; Propranolol | 2005 |
L-3,4-dihydroxyphenylalanine-induced c-Fos expression in the CNS under inhibition of central aromatic L-amino acid decarboxylase.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Cell Count; Central Nervous System; Dopamine Agents; Drug Interactions; Enzyme Inhibitors; Functional Laterality; Gene Expression Regulation; Hydrazines; Immunohistochemistry; Levodopa; Male; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2006 |
L-DOPA inhibits depolarization-induced [3H]GABA release in the dopamine-denervated globus pallidus of the rat: the effect is dopamine independent and mediated by D2-like receptors.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Data Interpretation, Statistical; Decarboxylation; Denervation; Dopamine; Dopamine Agents; Dopamine Antagonists; Enzyme Inhibitors; gamma-Aminobutyric Acid; Globus Pallidus; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Potassium; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Sulpiride; Sympathectomy, Chemical; Sympatholytics | 2006 |
In vivo antagonism of the behavioral responses to L-3-,4-dihydroxyphenylalanine by L-3-,4-dihydroxyphenylalanine cyclohexyl ester in conscious rats.
Topics: Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrazines; Levodopa; Male; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2009 |
Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons.
Topics: alpha-Synuclein; Animals; Animals, Newborn; Calbindins; Calcium; Calcium Channel Blockers; Cell Death; Cytosol; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electrochemistry; Enzyme Inhibitors; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Hydrazines; Levodopa; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2009 |
Direct angiotensin II type 2 receptor stimulation decreases dopamine synthesis in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzimidazoles; Biphenyl Compounds; Catheterization; Central Nervous System Agents; Corpus Striatum; Dopa Decarboxylase; Dopamine; Extracellular Space; Hydrazines; Imidazoles; Levodopa; Male; Microdialysis; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Tyrosine 3-Monooxygenase | 2010 |
Locomotor response to L-DOPA in reserpine-treated rats following central inhibition of aromatic L-amino acid decarboxylase: further evidence for non-dopaminergic actions of L-DOPA and its metabolites.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain Chemistry; Disease Models, Animal; Dopamine Agents; Drug Combinations; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Hydrazines; Hyperkinesis; Levodopa; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Receptor Agonists | 2010 |
Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways.
Topics: Aging; Animals; Dendrites; Dopamine; Hydrazines; Levodopa; Male; Neostriatum; Neural Pathways; Nucleus Accumbens; Phosphorylation; Phosphoserine; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2012 |
Voltammetric detection of L-dopa and carbidopa on graphene modified glassy carbon interfaces.
Topics: Carbidopa; Electrochemistry; Glass; Graphite; Hydrazines; Hydrogen-Ion Concentration; Levodopa; Nanostructures; Oxides | 2013 |
Tyrosine hydroxylase expression and activity in nigrostriatal dopaminergic neurons of MPTP-treated mice at the presymptomatic and symptomatic stages of parkinsonism.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Electrochemistry; Gene Expression Regulation; Hydrazines; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase | 2014 |
Yokukansan, a Traditional Japanese Medicine, Enhances the L-DOPA-Induced Rotational Response in 6-Hydroxydopamine-Lesioned Rats: Possible Inhibition of COMT.
Topics: Animals; Benserazide; Catechols; Cell Line; Corpus Striatum; Dopamine; Drugs, Chinese Herbal; Hydrazines; Levodopa; Male; Medicine, East Asian Traditional; Nitriles; Oxidopamine; Pargyline; Rats; Rats, Wistar | 2016 |
Neuroprotective effects of stemazole in the MPTP-induced acute model of Parkinson's disease: Involvement of the dopamine system.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benserazide; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Combinations; Hydrazines; Levodopa; Male; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Oxadiazoles; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase | 2016 |
Development and optimization of levodopa and benzylhydrazine orally disintegrating tablets by direct compression and response surface methodology.
Topics: Administration, Oral; Adult; Antiparkinson Agents; Cellulose; Chemistry, Pharmaceutical; Drug Combinations; Drug Liberation; Excipients; Female; Humans; Hydrazines; Levodopa; Male; Povidone; Starch; Tablets; Taste; Technology, Pharmaceutical; Young Adult | 2020 |