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hydralazine pyruvic acid hydrazone and hydralazine

hydralazine pyruvic acid hydrazone has been researched along with hydralazine in 4 studies

*Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent. [MeSH]

*Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent. [MeSH]

Compound Research Comparison

Studies
(hydralazine pyruvic acid hydrazone)
Trials
(hydralazine pyruvic acid hydrazone)
Recent Studies (post-2010)
(hydralazine pyruvic acid hydrazone)
Studies
(hydralazine)
Trials
(hydralazine)
Recent Studies (post-2010) (hydralazine)
7004,580364393

Protein Interaction Comparison

ProteinTaxonomyhydralazine pyruvic acid hydrazone (IC50)hydralazine (IC50)
MyeloperoxidaseHomo sapiens (human)1.265
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)3.649
LactoperoxidaseBos taurus (cattle)1.2

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ito, Y; Iwaki, M; Ogiso, T1
Prager, RH; Reece, PA; Stafford, I; Walker, GJ; Zacest, R1
Haegele, KD; Huff, SL; Shepherd, AM; Skrdlant, HB; Talseth, T1
Clementi, WA; Haegele, KD; McNay, JL; Shepherd, AM; Skrdlant, HB; Talseth, T1

Other Studies

4 other study(ies) available for hydralazine pyruvic acid hydrazone and hydralazine

ArticleYear
Pharmacokinetics and biotransformation of hydralazine acetone hydrazone, a metabolite of hydralazine, in the rat.
    Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:10

    Topics: Animals; Biological Availability; Biotransformation; Hydralazine; Hydrolysis; Injections, Intravenous; Male; Models, Biological; Rats; Rats, Inbred Strains

1989
Synthesis, formulation, and clinical pharmacological evaluation of hydralazine pyruvic acid hydrazone in two healthy volunteers.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:2

    Topics: Acetylation; Adult; Blood Pressure; Chemistry, Pharmaceutical; Drug Compounding; Drug Stability; Heart Rate; Humans; Hydralazine; Isomerism; Kinetics; Phenotype; Solutions

1985
Determination of hydralazine pyruvic acid hydrazone and its correlation with "apparent" hydralazine.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:2

    Topics: Acetylation; Administration, Oral; Animals; Humans; Hydralazine; Injections, Intravenous; Male; Phenotype; Rabbits

1981
Quantitative analysis of hydralazine pyruvic acid hydrazone, the major plasma metabolite of hydralazine.
    Journal of chromatography, 1980, Jan-04, Volume: 187, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Hydralazine; Rabbits

1980