Compounds > hydralazine

hydralazine and sirolimus

hydralazine has been researched along with sirolimus in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Asanuma, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Ogai, A; Papst, PJ; Sakata, Y; Terada, N; Ueda, Y1
Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Minamino, T; Node, K; Ogita, H; Sanada, S; Takashima, S1
Jin, X; Muslin, AJ; Siedlecki, AM1

Reviews

1 review(s) available for hydralazine and sirolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for hydralazine and sirolimus

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Inhibition of nitric oxide synthesis induces coronary vascular remodeling and cardiac hypertrophy associated with the activation of p70 S6 kinase in rats.
    Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Hydralazine; Imidazoles; Imidazolidines; Immunosuppressive Agents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases; Sirolimus; Ventricular Remodeling

2000
[Opening of ATP-sensitive potassium channel attenuates cardiac remodeling induced by chronic inhibition of nitric oxide synthesis].
    Journal of cardiology, 2003, Volume: 41, Issue:1

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiomegaly; Chromans; Hydralazine; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Ventricular Remodeling

2003
Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure.
    Kidney international, 2009, Volume: 75, Issue:8

    Topics: Animals; Blood Pressure; Cardiomegaly; Cardiomyopathy, Hypertrophic; Carrier Proteins; Extracellular Signal-Regulated MAP Kinases; Hydralazine; Mice; Phosphotransferases (Alcohol Group Acceptor); Ribosomal Protein S6 Kinases; Sirolimus; TOR Serine-Threonine Kinases

2009