Compounds > hydralazine

hydralazine and propylthiouracil

hydralazine has been researched along with propylthiouracil in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (9.09)	18.7374
1990's	2 (18.18)	18.2507
2000's	4 (36.36)	29.6817
2010's	4 (36.36)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Alarcón-Segovia, D; Kraus, A	1
Eldredge, NT; Jiller, JJ; van Robertson, WB	1
Jiang, X; Khursigara, G; Rubin, RL	1
Choi, HK; Merkel, PA; Niles, JL; Walker, AM	1
Niles, JL; Pendergraft, WF	1

Reviews

3 review(s) available for hydralazine and propylthiouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug-related lupus syndromes and their relationship to spontaneously occurring systemic lupus erythematosus. Bailliere's clinical rheumatology, 1991, Volume: 5, Issue:1 Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; Practolol; Propylthiouracil; Quinidine; Sulfasalazine	1991
Trojan horses: drug culprits associated with antineutrophil cytoplasmic autoantibody (ANCA) vasculitis. Current opinion in rheumatology, 2014, Volume: 26, Issue:1 Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Cocaine; Cocaine-Related Disorders; Drug Contamination; Humans; Hydralazine; Levamisole; Minocycline; Propylthiouracil	2014

Other Studies

8 other study(ies) available for hydralazine and propylthiouracil

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
The interaction of lupus-inducing drugs with deoxyribonucleic acid. Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2 Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immunodiffusion; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nucleic Acid Conformation; Nucleic Acid Denaturation; Optical Rotation; Oxazoles; Phenytoin; Procainamide; Propylthiouracil; Thymus Gland; Trimethadione; Viscosity	1974
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils. Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186 Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydrogen Peroxide; Isoniazid; Lupus Erythematosus, Systemic; Mice; Neutrophil Activation; Neutrophils; Peroxidase; Procainamide; Propylthiouracil; Quinidine; Tumor Cells, Cultured	1994
Drug-associated antineutrophil cytoplasmic antibody-positive vasculitis: prevalence among patients with high titers of antimyeloperoxidase antibodies. Arthritis and rheumatism, 2000, Volume: 43, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Antibodies; Antibodies, Antineutrophil Cytoplasmic; Female; Humans; Hydralazine; Male; Middle Aged; Penicillamine; Peroxidase; Propylthiouracil; Sulfasalazine; Vasculitis	2000