hydralazine and procainamide

hydralazine has been researched along with procainamide in 118 studies

Research

Studies (118)

Timeframe	Studies, this research(%)	All Research%
pre-1990	76 (64.41)	18.7374
1990's	16 (13.56)	18.2507
2000's	18 (15.25)	29.6817
2010's	7 (5.93)	24.3611
2020's	1 (0.85)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Drayer, DE; Reidenberg, MM	1
Jones, WN; Trinca, CE; Walson, PD	1
Gladkikh, SP; Piruzian, LA; Podymov, VK	2
Freeman, RW; Harbison, RD; Oates, JA; Woosley, RL	1
CHase, PH; Lee, SL	1
Carel, RS; Cordoba, O; Gutman, A; Shapiro, MS; Taragan, R	1
Fenster, PE; Pinnas, JL	1
Bach, JF; Dandavino, R	1
Schwarz, JA	1
Hayes, AH; Schneck, DW; Shiroff, RA; Sprouse, JS	1
DeWitt, FO; Hayes, AH; Miller, K; Schneck, DW; Sprouse, JS; Vary, JE	1
Maas, D; Schubothe, H	1
Cohmen, G	1
Katsutani, N; Shionoya, H	1
Rubin, RL	1
Koopman, WJ; Zacharias, W	1
Fritzler, MJ; Gohill, J; Pauls, JD	1
Sim, E	2
Burlingame, RW; Rubin, RL	1
Andersson, M; Dahlbäck, B; Englund, G; Hanson, A	1
Arndt, RE; Kotzin, BL; Portanova, JP; Tan, EM	1
Bernstein, RM; Craft, JE; Hardin, JA; Harding, MW; Radding, JA	1
Cornacchia, E; Golbus, J; Hanash, S; Maybaum, J; Richardson, B; Strahler, J	2
Biarese, V; Cargnino, M; Lerda, R; Lovisetto, P; Mairano, D; Marchi, L	1
Clark, DW	1
Kucharz, EJ	1
Honda, M; Nagoshi, H; Naito, M; Nishikai, M; Sato, A; Sugimoto, M	1
Boucek, RJ; Colburn, KK; Heng, MK; Weisbart, RH; Whang, SH; Yee, WS	1
Stevens, MB	1
Messner, RP; Thomas, TJ	1
Chan, EK; Pollard, KM; Rubin, RL; Tan, EM; Tang, FL; Tsay, G	1
Rubin, RL; Totoritis, MC	1
Barland, P; Epstein, A	1
de Boccardo, G; Drayer, D; Novogrodsky, A; Reidenberg, MM; Rubin, AL; Stenzel, KH	1
Kale, SA	1
Cush, JJ; Goldings, EA	1
Rasmussen, K	1
de Sèze, S; Dorfmann, H; Kahn, MF	2
Estes, D; Peltier, AP	1
Asboe-Hansen, G; Blumenkrantz, N	1
Tan, EM	1
Halberg, P; Kobayasi, T; Ullman, S; Wiik, A	1
Harpey, JP	1
McEwen, J	1
Almeyda, J; Levantine, A	1
Losada, M; Meruane, J	1
Eldredge, NT; Jiller, JJ; van Robertson, WB	1
Hart, FD	1
Feltkamp, TE; ten Veen, JH	1
ten Veen, JH	1
Blomgren, SE	1
Galea, G; Geavlete, A	1
Alarcón-Segovia, D	1
Catania, PN; King, JC	1
Lee, SL; Peress, NS; Siegel, M	1
Clark, BG; Vestal, RE	1
Skakun, NP	1
DeSwarte, RD	1
Reidenberg, MM	1
Jacobs, RP	1
Blackshear, PJ; Kahn, CR; Kriauciunas, KA; Rotner, HE	1
Wollina, U	1
Harmon, CE; Portanova, JP	1
Holborow, EJ	1
Balazs, T; Robinson, CJ	1
Agnello, VD; Joslin, FG; Portanova, JP; Rubin, RL; Tan, EM	1
Weinstein, A	1
Schoen, RT; Trentham, DE	1
Portanova, JP; Tan, EM	1
Hess, EV	2
Parker, CW	1
Greenblatt, DJ; Lloyd, BL	1
Kotler, MN; Segal, BL	1
Alloway, JA; Salata, MP	1
Edworthy, SM; Fritzler, MJ; Pauls, JD	1
Ayer, LM; Edworthy, SM; Fritzler, MJ	1
Jiang, X; Khursigara, G; Rubin, RL	1
Cohen, MG	1
Park, BK; Tingle, MD	1
Miyasaka, N	1
Ishizaki, T; Ohnishi, A	1
Chang, S; Hemati, N; Johnson, K; Richardson, B; Yung, R	1
Amano, K; Takeuchi, T	1
Attwood, J; Deng, C; Lu, Q; Rao, T; Richardson, B; Yung, R; Zhang, Z	1
Acuña, C; Chavez, A; Dueñas-Gonzalez, A; Lizano, M; Mariscal, I; Perez-Cardenas, E; Salazar, AM; Segura-Pacheco, B; Taja-Chayeb, L; Trejo-Becerril, C	1
Dzierzewicz, Z; Gwoździński, K; Jóźwiak, Z; Koceva-Chyła, A; Weglarz, L	1
Richardson, B	1
Lu, Q; Richardson, BC; Wu, A	1
Suwa, A	1
Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB	1
Nonaka, Y; Takei, S	1
Lu, Q; Zhou, Y	1
Del Giglio, M; Girolomoni, G; Schena, D; Vedove, CD	1
Crosti, C; Marzano, AV; Vezzoli, P	1
Katz, U; Zandman-Goddard, G	1
Chen, SJ; Hii, HP; Ka, SM; Liao, MH; Shih, CC; Tsao, CM; Wu, CC	1
Carmona-Rivera, C; Grayson, PC; Irizarry-Caro, JA; Kaplan, MJ; Khaznadar, SS; Schwartz, DM	1
He, Y; Sawalha, AH	1
Arnaud, L; Chasset, F; Gavand, PE; Lambert, A; Lebrun-Vignes, B; Martin, T; Mertz, P; Muller, C; Salem, JE; Sibilia, J; Tebacher-Alt, M	1
Guo, L; Guo, Y; Liao, S; Liu, HF; Pan, Q; Wang, S; Zhao, C	1

Reviews

34 review(s) available for hydralazine and procainamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug-induced systemic lupus erythematosus: a critical review. Seminars in arthritis and rheumatism, 1975, Volume: 5, Issue:1 Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agents; Contraceptives, Oral, Synthetic; Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Penicillamine; Procainamide; Psychotropic Drugs; Reserpine; Sulfonamides; Tuberculosis	1975
Drug-induced immune complex disease. Biochemical Society transactions, 1991, Volume: 19, Issue:1 Topics: Amino Acid Sequence; Antigen-Antibody Complex; Complement Activation; Complement C4; Humans; Hydralazine; Immune Complex Diseases; Lupus Erythematosus, Systemic; Molecular Sequence Data; Penicillamine; Procainamide	1991
Drug-induced immune-complex disease. Complement and inflammation, 1989, Volume: 6, Issue:2 Topics: Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Penicillamine; Practolol; Procainamide	1989
[Drug-induced lupus]. Recenti progressi in medicina, 1985, Volume: 76, Issue:2 Topics: Acetylation; Adrenergic beta-Antagonists; Antibodies, Antinuclear; Anticonvulsants; B-Lymphocytes; Diagnosis, Differential; HLA Antigens; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Penicillamine; Procainamide; Sulfasalazine; T-Lymphocytes, Regulatory	1985
Genetically determined variability in acetylation and oxidation. Therapeutic implications. Drugs, 1985, Volume: 29, Issue:4 Topics: Acetylation; Anticonvulsants; Antidepressive Agents, Tricyclic; Debrisoquin; Disease; Drug Interactions; Genetic Variation; Humans; Hydralazine; Isoniazid; Oxidation-Reduction; Pharmaceutical Preparations; Phenelzine; Phenotype; Procainamide; Racial Groups; Sparteine; Sulfasalazine	1985
[Pathogenesis of drug-induced collagenosis-like syndrome]. Przeglad lekarski, 1987, Volume: 44, Issue:5 Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide	1987
Connective tissue disease in the elderly. Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1 Topics: Aged; Connective Tissue Diseases; Dermatomyositis; Female; Giant Cell Arteritis; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Myositis; Polymyalgia Rheumatica; Procainamide; Scleroderma, Systemic; Sjogren's Syndrome; Vasculitis	1986
Drug-induced systemic lupus erythematosus. Differentiating it from the real thing. Postgraduate medicine, 1985, Feb-15, Volume: 77, Issue:3 Topics: Diagnosis, Differential; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Procainamide; Risk	1985
Drug-induced lupus: clinical spectrum and pathogenesis. The American journal of the medical sciences, 1985, Volume: 290, Issue:1 Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Black People; Brain; Chlorpromazine; Female; Heart; Humans; Hydralazine; Isoniazid; Kidney; Liver; Lung; Lupus Erythematosus, Systemic; Male; Methyldopa; Muscles; Phenotype; Procainamide	1985
Systemic lupus erythematosus. JAMA, 1973, Apr-30, Volume: 224, Issue:5 Suppl Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Hepatitis; Humans; Hydralazine; Immunoglobulins; Kidney; Lupus Erythematosus, Systemic; Male; Nephritis; Neutrophils; Prednisone; Procainamide; Prognosis; Skin	1973
[Iatrogenic lupus: present status of the problem. II. Physiopathology of induced lupus]. La Nouvelle presse medicale, 1972, Dec-09, Volume: 1, Issue:44 Topics: Animals; Antibodies, Antinuclear; Disease Models, Animal; DNA, Viral; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NZB; Neutrophils; Nucleic Acid Denaturation; Procainamide	1972
Antinuclear antibodies. Pathobiology annual, 1972, Volume: 2 Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Autoantigens; Cytotoxicity Tests, Immunologic; DNA; Fluorescent Antibody Technique; Humans; Hydralazine; Immune Adherence Reaction; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nephritis; Neutrophils; Nucleoproteins; Procainamide; Sjogren's Syndrome	1972
Lupus-like syndromes induced by drugs. Annals of allergy, 1974, Volume: 33, Issue:5 Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stranded; Drug-Related Side Effects and Adverse Reactions; False Positive Reactions; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydralazine; Isoantigens; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Neutrophils; Nucleoproteins; Penicillamine; Phenytoin; Procainamide; Remission, Spontaneous; Syphilis Serodiagnosis	1974
Cutaneous reactions to cardiovascular drugs. The British journal of dermatology, 1973, Volume: 88, Issue:3 Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Clonidine; Debrisoquin; Digitalis Glycosides; Drug Eruptions; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Mercury; Methyldopa; Nitroglycerin; Pentaerythritol Tetranitrate; Procainamide; Quinidine; Thiazines	1973
[Generalized lupus erythematosus caused by methyl-phenyl-ethyl-hydantoin]. Revista medica de Chile, 1967, Volume: 95, Issue:7 Topics: Adult; Autoimmune Diseases; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Mephenytoin; Procainamide	1967
Drug-induced lupus syndromes. Mayo Clinic proceedings, 1969, Volume: 44, Issue:9 Topics: Antibodies, Antinuclear; Anticonvulsants; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1969
[Pharmacokinetics of drug preparations metabolized by N-acetyltransferase]. Klinicheskaia meditsina, 1982, Volume: 60, Issue:1 Topics: Acetylation; Acetyltransferases; Dapsone; Humans; Hydralazine; Inactivation, Metabolic; Isoniazid; Kinetics; Liver; Pharmaceutical Preparations; Phenotype; Procainamide; Sulfamethazine; Sulfasalazine	1982
Drug-induced lupus: clinical and serological studies. Clinics in rheumatic diseases, 1982, Volume: 8, Issue:1 Topics: Acetyltransferases; Adult; Antibodies, Antinuclear; Anticonvulsants; Arthritis; Chlorpromazine; Cross Reactions; Female; Genes, MHC Class II; HLA-DR Antigens; Humans; Hydralazine; Hypertension; Isoniazid; Joint Diseases; Lupus Erythematosus, Systemic; Male; Middle Aged; Pain; Pleural Effusion; Pleurisy; Procainamide; T-Lymphocytes	1982
Drug-induced systemic lupus erythematosus. Progress in clinical immunology, 1980, Volume: 4 Topics: Antibodies, Antinuclear; Anticonvulsants; Chlorpromazine; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1980
Drug-induced lupus: an adjuvant disease? The American journal of medicine, 1981, Volume: 71, Issue:1 Topics: Adjuvants, Immunologic; Animals; Autoimmune Diseases; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide	1981
Quinidine-induced rheumatic syndromes. Seminars in arthritis and rheumatism, 1995, Volume: 24, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Atrial Fibrillation; Child; Diagnosis, Differential; Female; Hematologic Tests; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Middle Aged; Polymyalgia Rheumatica; Procainamide; Prognosis; Quinidine	1995
Drug-induced lupus. Internal medicine (Tokyo, Japan), 1996, Volume: 35, Issue:7 Topics: Antibodies, Antinuclear; Anticonvulsants; Ethosuximide; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Procainamide; Syndrome	1996
[Drug-induced pericarditis]. Ryoikibetsu shokogun shirizu, 1996, Issue:13 Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Humans; Hydralazine; Pericarditis; Procainamide	1996
[Drug-induced lupus erythematosus]. Ryoikibetsu shokogun shirizu, 2000, Issue:31 Topics: Autoimmunity; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Prognosis	2000
DNA methylation and autoimmune disease. Clinical immunology (Orlando, Fla.), 2003, Volume: 109, Issue:1 Topics: Animals; Autoimmune Diseases; Autoimmunity; Azacitidine; Cell Communication; DNA Methylation; Humans; Hydralazine; In Vitro Techniques; Lupus Erythematosus, Systemic; Models, Immunological; Procainamide; T-Lymphocytes	2003
[Immunologic tests: Anti-histone antibodies]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 7 Topics: Antibodies, Antinuclear; Biomarkers; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Histones; Humans; Hydralazine; Immunoblotting; Lupus Erythematosus, Systemic; Lupus Vulgaris; Procainamide	2005
[Drug-induced lupus erythematosus]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Time Factors	2007
DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients. Autoimmunity reviews, 2008, Volume: 7, Issue:5 Topics: Autoantibodies; B-Lymphocytes; CD4-Positive T-Lymphocytes; Cytokines; Cytotoxicity, Immunologic; DNA Methylation; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; T-Lymphocyte Subsets	2008
Drug-induced lupus erythematosus. Archives of dermatological research, 2009, Volume: 301, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Antibodies; Antifungal Agents; Antihypertensive Agents; Antitubercular Agents; Arthritis; Calcium Channel Blockers; Exanthema; Humans; Hydralazine; Interferons; Isoniazid; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Naphthalenes; Procainamide; Serositis; Sodium Chloride Symporter Inhibitors; Terbinafine; Tumor Necrosis Factor-alpha	2009
Drug-induced lupus: an update on its dermatologic aspects. Lupus, 2009, Volume: 18, Issue:11 Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antitubercular Agents; Autoantibodies; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Minocycline; Procainamide; Skin Diseases	2009
Drug-induced lupus: an update. Autoimmunity reviews, 2010, Volume: 10, Issue:1 Topics: Anti-Arrhythmia Agents; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Tumor Necrosis Factor-alpha	2010
Drug-induced lupus erythematosus: an update on drugs and mechanisms. Current opinion in rheumatology, 2018, Volume: 30, Issue:5 Topics: Autoimmunity; Genetic Predisposition to Disease; Humans; Hydralazine; Immunologic Factors; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Procainamide; Tumor Necrosis Factor-alpha	2018
Mechanistic Insights of Chemicals and Drugs as Risk Factors for Systemic Lupus Erythematosus. Current medicinal chemistry, 2020, Volume: 27, Issue:31 Topics: Autoimmune Diseases; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Risk Factors	2020

Other Studies

84 other study(ies) available for hydralazine and procainamide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Clinical consequences of polymorphic acetylation of basic drugs. Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:3 Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Pharmaceutical Preparations; Phenelzine; Phenotype; Polymorphism, Genetic; Procainamide; Sulfasalazine	1977
Drug-induced systemic lupus erythematosus. Arizona medicine, 1978, Volume: 35, Issue:1 Topics: Anticonvulsants; Antihypertensive Agents; Antipsychotic Agents; Antitubercular Agents; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Procainamide	1978
[Molecular aspects of disorders in fibrillogenesis of connective tissue caused by medicinal ligands]. Doklady Akademii nauk SSSR, 1979, Jun-11, Volume: 246, Issue:5 Topics: Animals; Connective Tissue; Humans; Hydralazine; Isoniazid; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase	1979
[Molecular aspects of connective tissue fibrillogenesis disorders caused by drug ligands]. Doklady Akademii nauk SSSR, 1979, Volume: 246, Issue:5 Topics: Animals; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Elastin; Humans; Hydralazine; Isoniazid; Ligands; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase	1979
Evidence for the biotransformation of procainamide to a reactive metabolite. Toxicology and applied pharmacology, 1979, Volume: 50, Issue:1 Topics: Acetylation; Animals; Biotransformation; Hydralazine; Male; Mice; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Procainamide; Salmonella typhimurium	1979
LE cells in pleural fluid. Arthritis and rheumatism, 1979, Volume: 22, Issue:8 Topics: Aged; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Neutrophils; Pleural Effusion; Procainamide	1979
ANA, DNA, and SLE. Arizona medicine, 1977, Volume: 31, Issue:4 Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; DNA; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide	1977
[Disseminated lupus erythematosus: etiopathogenic factors]. Annales de medecine interne, 1977, Volume: 128, Issue:1 Topics: Animals; Antibodies; Autoantibodies; B-Lymphocytes; Female; Humans; Hydantoins; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Mice; Mice, Inbred NZB; Mice, Inbred Strains; Procainamide; Sunlight; T-Lymphocytes; Virus Diseases	1977
[Drug-induced disorders of lupus erythematosus type (author's transl)]. Arzneimittel-Forschung, 1977, Volume: 27, Issue:96 Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Penicillamine; Procainamide; Rats	1977
The effect of hydralazine and other drugs on the kinetics of procainamide acetylation by rat liver and kidney N-acetyltransferase. The Journal of pharmacology and experimental therapeutics, 1978, Volume: 204, Issue:1 Topics: Acetylation; Acetyltransferases; Animals; Hydralazine; In Vitro Techniques; Kinetics; Liver; Male; Procainamide; Rats	1978
Plasma levels of free and acid-labile hydralazine: effects of multiple dosing and of procainamide. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:6 Topics: Acetylation; Adult; Drug Interactions; Female; Humans; Hydralazine; Male; Phenotype; Procainamide; Time Factors	1978
[Drug-induced systemic lupus erythematosus (author's transl)]. Immunitat und Infektion, 1977, Volume: 5, Issue:4 Topics: Adolescent; Aged; Anti-Bacterial Agents; Antibody Formation; Autoantibodies; Child; Chlorpromazine; Female; Humans; Hydralazine; Immune Tolerance; Lupus Erythematosus, Systemic; Methyldopa; Practolol; Procainamide	1977
[Drug-induced lupus erythematosus-like syndromes]. Medizinische Klinik, 1976, May-07, Volume: 71, Issue:19 Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Anticonvulsants; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydantoins; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Lymphocytes; Male; Middle Aged; Procainamide	1976
Drug-specific immune responses induced by procainamide, hydralazine and isoniazid in guinea-pigs. International journal of immunopharmacology, 1992, Volume: 14, Issue:4 Topics: Animals; Antibodies; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Hydralazine; Isoniazid; Ovalbumin; Penicillins; Procainamide; Serum Albumin, Bovine	1992
Autoantibody specificity in drug-induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs. Clinical biochemistry, 1992, Volume: 25, Issue:3 Topics: Antibody Specificity; Autoantibodies; Chromatin; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Neutrophils; Procainamide; Quinidine	1992
Lupus-inducing drugs alter the structure of supercoiled circular DNA domains. Arthritis and rheumatism, 1990, Volume: 33, Issue:3 Topics: Acecainide; Animals; Antibodies; Canavanine; DNA, Superhelical; Electrophoresis, Agar Gel; Escherichia coli; Hydralazine; Lupus Erythematosus, Systemic; Plasmids; Procainamide	1990
Antibodies from patients with systemic lupus erythematosus and drug-induced lupus bind determinants on histone 5 (H5). Molecular immunology, 1990, Volume: 27, Issue:8 Topics: Amino Acid Sequence; Animals; Autoantibodies; Chickens; Cross Reactions; Epitopes; Histones; Humans; Hydralazine; Immunoblotting; Lupus Erythematosus, Systemic; Molecular Sequence Data; Peptides; Procainamide	1990
Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin. The Journal of clinical investigation, 1991, Volume: 88, Issue:2 Topics: Autoantibodies; Chlorpromazine; Chromatin; DNA; Enzyme-Linked Immunosorbent Assay; Histones; Humans; Hydralazine; Immunoglobulin G; Immunoglobulin M; Lupus Vulgaris; Procainamide; Quinidine	1991
Inhibition of complement components C3 and C4 by cadralazine and its active metabolite. European journal of clinical pharmacology, 1991, Volume: 40, Issue:3 Topics: Antihypertensive Agents; Complement C3; Complement C4; Dihydralazine; Humans; Hydralazine; Hydroxylamine; Hydroxylamines; Procainamide; Pyridazines; Vasodilator Agents	1991
Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions. Journal of immunology (Baltimore, Md. : 1950), 1987, Jan-15, Volume: 138, Issue:2 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Epitopes; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Macromolecular Substances; Mice; Peptide Fragments; Procainamide	1987
Autoantigenic histone epitopes: a comparison between procainamide- and hydralazine-induced lupus. Arthritis and rheumatism, 1987, Volume: 30, Issue:6 Topics: Autoantigens; Epitopes; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide	1987
N-acetylprocainamide is a less potent inducer of T cell autoreactivity than procainamide. Arthritis and rheumatism, 1988, Volume: 31, Issue:8 Topics: Acecainide; Autoantibodies; Autoimmune Diseases; Chromatography, High Pressure Liquid; DNA; Humans; Hydralazine; In Vitro Techniques; Methylation; Phthalazines; Procainamide; T-Lymphocytes	1988
Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity. Journal of immunology (Baltimore, Md. : 1950), 1988, Apr-01, Volume: 140, Issue:7 Topics: Autoimmune Diseases; DNA (Cytosine-5-)-Methyltransferases; Humans; Hydralazine; Immunosuppressive Agents; Lupus Vulgaris; Lymphocyte Activation; Procainamide; T-Lymphocytes	1988
[Procainamide- and hydralazine-induced antinuclear antibodies in Japanese]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1987, Volume: 76, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Asian People; Female; Humans; Hydralazine; Japan; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide	1987
Antiguanosine antibodies: a new marker for procainamide-induced systemic lupus erythematosus. Annals of internal medicine, 1986, Volume: 104, Issue:3 Topics: Adult; Aged; Antibodies, Antinuclear; DNA, Single-Stranded; Female; Fluorescent Antibody Technique; Guanosine; Histones; Humans; Hydralazine; Immunoglobulin G; Lupus Erythematosus, Systemic; Male; Middle Aged; Nucleosides; Procainamide	1986
Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA. Arthritis and rheumatism, 1986, Volume: 29, Issue:5 Topics: Canavanine; Circular Dichroism; DNA; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Nucleic Acid Conformation; Penicillamine; Polydeoxyribonucleotides; Procainamide	1986
IgG subclasses of autoantibodies in systemic lupus erythematosus, Sjogren's syndrome, and drug-induced autoimmunity. Journal of immunology (Baltimore, Md. : 1950), 1986, Oct-15, Volume: 137, Issue:8 Topics: Antibodies, Monoclonal; Autoantibodies; Autoimmune Diseases; DNA; Enzyme-Linked Immunosorbent Assay; Histones; Humans; Hydralazine; Immunoglobulin G; Lupus Erythematosus, Systemic; Procainamide; Quinidine; Sjogren's Syndrome	1986
Drug-induced lupus. Genetic, clinical, and laboratory features. Postgraduate medicine, 1985, Sep-01, Volume: 78, Issue:3 Topics: Aged; Antibodies, Antinuclear; Diagnosis, Differential; Humans; Hydralazine; Immunoglobulins; Lupus Erythematosus, Systemic; Procainamide; Risk; Time Factors	1985
The diagnostic value of antihistone antibodies in drug-induced lupus erythematosus. Arthritis and rheumatism, 1985, Volume: 28, Issue:2 Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Child; Disopyramide; Female; Fluorescent Antibody Technique; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Middle Aged; Penicillamine; Phenytoin; Procainamide	1985
Inhibition of pokeweed mitogen-induced B cell differentiation by compounds containing primary amine or hydrazine groups. Clinical and experimental immunology, 1985, Volume: 59, Issue:1 Topics: Adult; B-Lymphocytes; Cadaverine; Cell Differentiation; Depression, Chemical; Diamines; Hemolytic Plaque Technique; Humans; Hydralazine; Immunoglobulin G; Immunosuppressive Agents; Lymphocyte Activation; Lymphokines; Middle Aged; Pokeweed Mitogens; Procainamide	1985
[Drug-induced lupus erythematosus disseminatus]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Apr-10, Volume: 92, Issue:10 Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; Antithyroid Agents; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide	1972
Connective-tissue effects of drugs causing lupoid syndrome. Acta dermato-venereologica, 1974, Volume: 54, Issue:1 Topics: Animals; Carbon Radioisotopes; Chick Embryo; Chlorpromazine; Collagen; Depression, Chemical; Glucosamine; Hydralazine; Hydroxylation; Hydroxylysine; Hydroxyproline; Lupus Erythematosus, Systemic; Lysine; Mucoproteins; Procainamide; Proline; Tibia	1974
Drug-induced autoimmune disease. Federation proceedings, 1974, Volume: 33, Issue:8 Topics: Acetyltransferases; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Binding Sites; DNA; Epitopes; Humans; Hydralazine; Immunodiffusion; Lupus Erythematosus, Systemic; Nucleic Acid Conformation; Nucleoproteins; Procainamide; Protein Binding	1974
Drug-induced lupus erythematosus syndrome. Immuno-pathological, electronmicroscopical and serological studies. Acta dermato-venereologica, 1974, Volume: 54, Issue:5 Topics: Adult; Animals; Antibodies, Antinuclear; Biopsy; Complement Fixation Tests; Female; Fluorescent Antibody Technique; Humans; Hydralazine; Immune Sera; Immunoglobulin G; Immunoglobulin M; Leukocytes; Lupus Erythematosus, Systemic; Male; Microscopy, Electron; Microscopy, Fluorescence; Middle Aged; Procainamide; Rabbits; Skin	1974
Letter: Aetiology of systemic lupus erythematosus. Lancet (London, England), 1974, Dec-28, Volume: 2, Issue:7896 Topics: Acetylation; Antibody Formation; DNA; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1974
The interaction of lupus-inducing drugs with deoxyribonucleic acid. Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2 Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immunodiffusion; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nucleic Acid Conformation; Nucleic Acid Denaturation; Optical Rotation; Oxazoles; Phenytoin; Procainamide; Propylthiouracil; Thymus Gland; Trimethadione; Viscosity	1974
Drug-induced arthritis. Current medical research and opinion, 1974, Volume: 2, Issue:9 Topics: Acute Disease; Anticoagulants; Antihypertensive Agents; Arteritis; Arthritis; Barbiturates; Contraceptives, Oral; Digitalis Glycosides; Drug-Related Side Effects and Adverse Reactions; Edema; Gout; Humans; Hydralazine; Iatrogenic Disease; Lupus Erythematosus, Systemic; Mersalyl; Osteomalacia; Osteoporosis; Penicillins; Procainamide; Pyrazinamide; Succinylcholine; Sulfonamides; Water-Electrolyte Balance	1974
[Iatrogenic lupus: current status of the question. I. Clinical study and main drugs responsible]. La Nouvelle presse medicale, 1972, Dec-02, Volume: 1, Issue:43 Topics: Antibodies, Antinuclear; Contraceptives, Oral; Diagnosis, Differential; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Procainamide; Sulfonamides	1972
Medical grand rounds--from the Medical College of Virginia. Drug-induced lupus erythematosus. Virginia medical monthly, 1974, Volume: 101, Issue:4 Topics: Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Disease Susceptibility; DNA; DNA, Single-Stranded; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Procainamide; Tuberculosis, Pulmonary	1974
Studies on drug induced lupus erythematosus in mice. I. Drug induced antinuclear antibodies (ANA). Clinical and experimental immunology, 1972, Volume: 11, Issue:2 Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Antibody Formation; Chlorthalidone; Coombs Test; DNA; Female; Fluorescent Antibody Technique; Genetics; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Methyldopa; Mice; Mice, Inbred Strains; Procainamide; Sex Factors	1972
Studies on drug-induced lupus erythematosus in mice. II. Drug-induced smooth muscle and skeletal muscle antibodies. Clinical and experimental immunology, 1973, Volume: 15, Issue:3 Topics: Animals; Antibody Formation; Autoantibodies; Cell Membrane; Chlorthalidone; Fluorescent Antibody Technique; Hydralazine; Isoniazid; Liver; Lupus Erythematosus, Systemic; Lymphocytes; Methyldopa; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Muscle, Smooth; Muscles; Procainamide	1973
Drug-induced lupus erythematosus. Seminars in hematology, 1973, Volume: 10, Issue:4 Topics: Antibodies; Cell Membrane; DNA; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Prednisone; Procainamide	1973
[Medicaments as iatrogenic factors in the onset of lupoid syndromes]. Medicina interna, 1974, Volume: 26, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Phenytoin; Procainamide	1974
Drug-induced lupus syndrome. The Medical letter on drugs and therapeutics, 1974, Apr-12, Volume: 16, Issue:8 Topics: Acetylation; Anticonvulsants; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male; Procainamide	1974
The physico-chemical incompatibilities of selected cardiovascular and psychotherapeutic agents with sodium ethacrynate. American journal of hospital pharmacy, 1972, Volume: 29, Issue:2 Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Chlorpromazine; Drug Combinations; Drug Compounding; Drug Incompatibility; Drug Stability; Ethacrynic Acid; Hydralazine; Hydrogen-Ion Concentration; Procainamide; Prochlorperazine; Promazine; Reserpine; Spectrum Analysis; Time Factors; Tolazoline; Tranquilizing Agents; Triflupromazine; Ultraviolet Rays	1972
Drug-induced lupus syndromes. British medical journal, 1970, Apr-25, Volume: 2, Issue:5703 Topics: Anticonvulsants; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Procainamide	1970
Drug-induced systemic lupus erythematosus. JAMA, 1969, Apr-21, Volume: 208, Issue:3 Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide	1969
The epidemiology of drug-induced systemic lupus erythematosus. Arthritis and rheumatism, 1967, Volume: 10, Issue:5 Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; New York City; Phenytoin; Procainamide	1967
Adverse drug reactions in the elderly: case studies. Geriatrics, 1984, Volume: 39, Issue:12 Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonidine; Dienestrol; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydralazine; Lung Diseases; Male; Middle Aged; Nitrofurantoin; Pancreatitis; Papaverine; Peripheral Nervous System Diseases; Procainamide; Propranolol; Sulindac; Theophylline; Timolol	1984
Drug allergy--problems and strategies. The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 1 Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Encephalomyelitis, Acute Disseminated; Exanthema; Humans; Hydralazine; Immunity, Cellular; Isoniazid; Kidney Diseases; Liver Diseases; Lupus Erythematosus, Systemic; Lymphoid Tissue; Methyldopa; Nephritis, Interstitial; Penicillins; Phenytoin; Procainamide; Respiratory Hypersensitivity; Vasculitis, Leukocytoclastic, Cutaneous	1984
The chemical induction of systemic lupus erythematosus and lupus-like illnesses. Arthritis and rheumatism, 1981, Volume: 24, Issue:8 Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythematosus, Systemic; Lupus Vulgaris; Lymphocytes; Phenotype; Procainamide; Time Factors	1981
Drug-induced rheumatic diseases. Comprehensive therapy, 1984, Volume: 10, Issue:8 Topics: Adrenal Cortex Hormones; Anticonvulsants; Antineoplastic Agents; Diuretics; Gout; Heparin; Humans; Hydralazine; Lupus Erythematosus, Systemic; Myositis; Osteomalacia; Osteonecrosis; Osteoporosis; Procainamide; Rheumatic Diseases; Scleroderma, Systemic; Thyroid Hormones; Uric Acid	1984
Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus. Annals of internal medicine, 1983, Volume: 99, Issue:2 Topics: Aged; Autoantibodies; Autoimmune Diseases; Female; Glucose Tolerance Test; Humans; Hydralazine; Hypoglycemia; Insulin; Lupus Erythematosus, Systemic; Procainamide	1983
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Mar-01, Volume: 39, Issue:5 Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; Phenylbutazone; Phenytoin; Procainamide; Syndrome	1984
Drug effects on autoantibodies and immune complexes. Agents and actions. Supplements, 1980, Volume: 7 Topics: Acetylation; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Binding Sites; Complement C1; Humans; Hydralazine; Immunoglobulin M; Lupus Erythematosus, Systemic; Methyldopa; Penicillamine; Procainamide; Rheumatoid Factor	1980
Drug-induced antinuclear antibodies in the guinea pig. Life sciences, 1982, Jan-11, Volume: 30, Issue:2 Topics: Acetanilides; Animals; Antibodies, Antinuclear; Antibody Formation; Caffeine; Guinea Pigs; Hydralazine; Male; Procainamide	1982
Reactivity of anti-histone antibodies induced by procainamide and hydralazine. Clinical immunology and immunopathology, 1982, Volume: 25, Issue:1 Topics: Adult; Aged; Animals; Antibodies, Antinuclear; Antibody Specificity; Autoantibodies; Connective Tissue Diseases; Female; Histones; Humans; Hydralazine; Immunoglobulin G; Immunoglobulin M; Joint Diseases; Male; Mice; Middle Aged; Procainamide	1982
The role of histones as nuclear autoantigens in drug-related lupus erythematosus. Arthritis and rheumatism, 1981, Volume: 24, Issue:8 Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Antibody Specificity; Antigens; Autoantigens; Cell Nucleus; Chromosomal Proteins, Non-Histone; Fluorescent Antibody Technique; Histones; Humans; Hydralazine; Kidney; Lupus Erythematosus, Systemic; Mice; Procainamide	1981
Drug-related lupus. Arthritis and rheumatism, 1982, Volume: 25, Issue:7 Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide	1982
Introduction to drug-related lupus. Arthritis and rheumatism, 1981, Volume: 24, Issue:8 Topics: Acetylation; Acetyltransferases; Animals; Anticonvulsants; Autoimmune Diseases; Child; Chlorpromazine; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Phenothiazines; Procainamide; Sulfadiazine	1981
Hapten immunology and allergic reactions in humans. Arthritis and rheumatism, 1981, Volume: 24, Issue:8 Topics: Animals; Autoimmune Diseases; Carrier Proteins; Drug Hypersensitivity; Environmental Health; Haptens; HLA Antigens; Humans; Hydralazine; Immunization, Passive; Isoniazid; Lupus Erythematosus, Systemic; Macromolecular Substances; Methyldopa; Nitrobenzenes; Nucleic Acids; Penicillins; Procainamide	1981
Neuropsychiatric sequelae of pharmacotherapy of cardiac arrhythmias and hypertension. Journal of clinical psychopharmacology, 1981, Volume: 1, Issue:6 Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Brain; Drug Interactions; Guanethidine; Humans; Hydralazine; Hypertension; Lidocaine; Methyldopa; Procainamide; Psychotropic Drugs; Quinidine; Seizures	1981
The inflamed heart: pericarditis in the elderly. Geriatrics, 1980, Volume: 35, Issue:1 Topics: Aged; Cardiac Tamponade; Daunorubicin; Echocardiography; Heart Neoplasms; Humans; Hydralazine; Myocardial Infarction; Pericarditis; Pericarditis, Constrictive; Postpericardiotomy Syndrome; Procainamide; Syndrome; Uremia	1980
Epitope mapping of histone 5 (H5) with systemic lupus erythematosus, procainamide-induced lupus and hydralazine-induced lupus sera. Molecular immunology, 1993, Volume: 30, Issue:8 Topics: Amino Acid Sequence; Antibody Specificity; Autoantibodies; Blotting, Western; Epitopes; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Molecular Sequence Data; Procainamide; Protein Conformation	1993
Effect of procainamide and hydralazine on poly (ADP-ribosylation) in cell lines. Lupus, 1993, Volume: 2, Issue:3 Topics: Acecainide; Cell Line, Transformed; Humans; Hydralazine; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Procainamide; Tumor Cells, Cultured	1993
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils. Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186 Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydrogen Peroxide; Isoniazid; Lupus Erythematosus, Systemic; Mice; Neutrophil Activation; Neutrophils; Peroxidase; Procainamide; Propylthiouracil; Quinidine; Tumor Cells, Cultured	1994
Antibodies to dsDNA in drug induced lupus erythematosus. The Journal of rheumatology, 1994, Volume: 21, Issue:3 Topics: Antibodies, Antinuclear; Artifacts; DNA; Humans; Hydralazine; Lupus Erythematosus, Systemic; Nucleic Acid Denaturation; Procainamide; Timolol	1994
The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug-induced blood dyscrasias. British journal of clinical pharmacology, 1993, Volume: 36, Issue:1 Topics: Animals; Dapsone; Drug-Related Side Effects and Adverse Reactions; Erythrocyte Count; Hematologic Diseases; Humans; Hydralazine; In Vitro Techniques; Liver; Male; Methemoglobin; Microsomes, Liver; Models, Biological; Neutrophils; Pharmaceutical Preparations; Primaquine; Procainamide; Rats; Rats, Wistar	1993
Mechanisms of drug-induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo. Arthritis and rheumatism, 1997, Volume: 40, Issue:8 Topics: Animals; Antibody Formation; Autoantibodies; Autoimmunity; DNA Methylation; Female; Gene Expression; Hydralazine; Hydroxyurea; Lupus Vulgaris; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Male; Mice; Mice, Inbred AKR; Mice, Inbred NZB; Procainamide; T-Lymphocytes	1997
Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling. Arthritis and rheumatism, 2003, Volume: 48, Issue:3 Topics: Animals; Autoimmunity; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Hydralazine; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Lupus Erythematosus, Systemic; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Procainamide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; T-Lymphocytes	2003
Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:5 Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Hydralazine; Mice; Mice, Nude; Procainamide; Receptors, Estrogen; Receptors, Retinoic Acid; Tumor Cells, Cultured; Uterine Cervical Neoplasms	2003
Evaluation of hydralazine and procainamide effects on fibroblast membrane fluidity. Biochimie, 2003, Volume: 85, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Cell Membrane; Cells, Cultured; Cricetinae; Electron Spin Resonance Spectroscopy; Fibroblasts; Hydralazine; Membrane Fluidity; Mice; NIH 3T3 Cells; Procainamide; Spectrometry, Fluorescence	2003
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. Journal of immunology (Baltimore, Md. : 1950), 2005, May-15, Volume: 174, Issue:10 Topics: 5' Flanking Region; Adult; Antigens, CD; Base Sequence; CD27 Ligand; Cells, Cultured; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Hydralazine; Jurkat Cells; Lupus Erythematosus, Systemic; Membrane Proteins; Middle Aged; Molecular Sequence Data; Procainamide; Promoter Regions, Genetic; RNA, Messenger; T-Lymphocyte Subsets	2005
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. Molecular cancer therapeutics, 2005, Volume: 4, Issue:10 Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction	2005
Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats. PloS one, 2016, Volume: 11, Issue:2 Topics: Acidosis; Animals; Bicarbonates; Biomarkers; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Drug Evaluation, Preclinical; Electrolytes; Endotoxemia; Endotoxins; Hydralazine; Hypertension; Interleukin-6; Kidney; Lung; Male; Muscle, Skeletal; Neutrophils; Procainamide; Random Allocation; Rats; Rats, Wistar; Rhabdomyolysis; Superoxides; Tachycardia	2016
Brief Report: Drugs Implicated in Systemic Autoimmunity Modulate Neutrophil Extracellular Trap Formation. Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:3 Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antipsychotic Agents; Autoimmunity; Clozapine; Extracellular Traps; Flow Cytometry; Humans; Hydralazine; Microscopy, Fluorescence; Minocycline; Neutrophils; Procainamide; Proteomics; Signal Transduction	2018
Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database. Annals of the rheumatic diseases, 2019, Volume: 78, Issue:4 Topics: Adalimumab; Adult; Antirheumatic Agents; Databases, Factual; Etanercept; Female; Humans; Hydralazine; Infliximab; Lupus Erythematosus, Systemic; Male; Middle Aged; Pharmacovigilance; Procainamide; Retrospective Studies; World Health Organization	2019