hydralazine and phenylephrine

hydralazine has been researched along with phenylephrine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199011 (44.00)18.7374
1990's7 (28.00)18.2507
2000's4 (16.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Diamond, J; Janis, RA1
Krames, E; Levinson, G; Ring, G; Shnider, SM; Wallis, KL1
Chaudhuri, G; Cuevas, JM; Ignarro, LJ; Vargas, HM1
Fornal, CA; Jacobs, BL; Litto, WJ; Morilak, DA1
Koike, H; Miyamoto, M; Sada, T1
Hirt, E; Lockette, W; Otsuka, Y1
Bompart, F; Graham, BR; Liu, JB; Prichard, BN; Tomlinson, B1
Arnstein, MJ; Clough, DP; Major, JS; Oldham, AA1
Beckett, AH; Frohn, MJ; Jones, GR1
Babbs, CF; Chan, RC; Lamar, CH; Vetter, RJ1
Abel, PW; Hermsmeyer, K; Trapani, A; Worcel, M1
Brown, NL; Chevillard, C; Worcel, M1
Gomes, GI; Gould, L; Patel, S; Reddy, CV1
Allam, M; Gurney, AM1
Downing, GJ; Kadado, TR; Maulik, D; Phillips, C1
Fuchs, LC; Johnson, AK; Lamping, KG; Nuno, D1
Ezimokhai, M1
Butcher, JW; Kasparov, S; Paton, JF1
Brunori, A; Cogo, CE; Mary, DA; Molinari, C; Picchio, V; Ruggeri, P; Vacca, G1
Henrion, D; Loufrani, L1
Fornal, CA; Jacobs, BL; Martin-Cora, FJ1
Colton, I; Gokina, N; Maille, N; MandalĂ , M; Osol, G1
Bhandare, AM; Farnham, MM; Kapoor, K; Mohammed, S; Nedoboy, PE; Pilowsky, PM1

Trials

2 trial(s) available for hydralazine and phenylephrine

ArticleYear
Long-term inhibition of angiotensin converting enzyme suppresses calcium channel agonist-induced contraction of aorta in hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 14, Issue:6

    Topics: Animals; Aorta; Blood Pressure; Calcium Channel Agonists; Calcium Chloride; Dose-Response Relationship, Drug; Hydralazine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thiazepines

1989
Vasodilating mechanism and response to physiological pressor stimuli of acute doses of carvedilol compared with labetalol, propranolol and hydralazine.
    Drugs, 1988, Volume: 36 Suppl 6

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Cold Temperature; Double-Blind Method; Exercise; Heart Rate; Hemodynamics; Humans; Hydralazine; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine; Posture; Propanolamines; Propranolol; Vasodilator Agents

1988

Other Studies

23 other study(ies) available for hydralazine and phenylephrine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increases in cyclic GMP levels may not mediate relaxant effects of sodium nitroprusside, verapamil and hydralazine in rat vas deferens.
    Nature, 1978, Feb-02, Volume: 271, Issue:5644

    Topics: Animals; Cyclic GMP; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Phenylephrine; Rats; Vas Deferens; Verapamil

1978
Comparison of nitroprusside and hydralazine in hypertensive pregnant ewes.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:5

    Topics: Animals; Cardiac Output; Female; Ferricyanides; Heart Rate; Hydralazine; Hypertension; Nitroprusside; Phenylephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Sheep; Uterus; Vascular Resistance

1977
Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Hydralazine; In Vitro Techniques; Male; Nitrates; Nitric Acid; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Penicillamine; Phenylephrine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; Sympathetic Nervous System; Vasodilation; Vasopressins

1991
Single-unit responses of serotonergic neurons to vasoactive drug administration in behaving cats.
    The American journal of physiology, 1990, Volume: 259, Issue:5 Pt 2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Blood Pressure; Cats; Female; Heart Rate; Hydralazine; Injections, Intravenous; Male; Methoxydimethyltryptamines; Neurons; Nitroprusside; Phenylephrine; Raphe Nuclei; Serotonin; Serotonin Antagonists; Sleep Stages; Tetrahydronaphthalenes

1990
The endothelium and cyclic guanosine monophosphate in hyperthyroid-induced hypertension.
    Agents and actions. Supplements, 1987, Volume: 22

    Topics: Acetylcholine; Animals; Biological Products; Cyclic GMP; Hydralazine; Hypertension; Hyperthyroidism; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Phenylephrine; Rats; Rats, Inbred Strains; Vasodilation

1987
Non-specific inhibition of pressor agents in vivo by the renin inhibitor pepstatin A.
    Journal of hypertension, 1984, Volume: 2, Issue:2

    Topics: Animals; Blood Pressure; Captopril; Female; Hydralazine; Oligopeptides; Pepstatins; Phenylephrine; Rats; Rats, Inbred Strains; Renin; Swine; Time Factors; Vasopressins

1984
Liminal therapy: a strategy for the complete and selective destruction of malignant tissue in situ.
    Medical hypotheses, 1984, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Survival; Dihydralazine; Drug Resistance; Energy Metabolism; Humans; Hydralazine; Isoproterenol; Mice; Naphazoline; Neoplasms; Oxygen; Oxygen Consumption; Phenylephrine; Sarcoma, Experimental; Time Factors; Vasopressins

1984
Abnormal response of tumor vasculature to vasoactive drugs.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:1

    Topics: Animals; Cardiac Output; Cerebrovascular Circulation; Hydralazine; Male; Neoplasms, Experimental; Phenylephrine; Rats; Rats, Inbred F344; Regional Blood Flow; Renal Circulation; Stomach; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

1984
Effect of hydralazine on tension and membrane potential in the rat caudal artery.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Animals; Arteries; Hydralazine; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Rats; Stimulation, Chemical

1983
Pre- and postjunctional actions of hydralazine in vascular and nonvascular smooth muscle in vitro.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:2

    Topics: Animals; Hydralazine; In Vitro Techniques; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Neuromuscular Junction; Phenylephrine; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Time Factors

1983
Paradoxical response to the vasodilators.
    Angiology, 1982, Volume: 33, Issue:2

    Topics: Blood Pressure; Heart Failure; Heart Rate; Hemodynamics; Humans; Hydralazine; Male; Middle Aged; Mitral Valve Stenosis; Nitroprusside; Phenylephrine; Pulmonary Artery; Vasodilator Agents

1982
Inhibition of calcium release from the sarcoplasmic reticulum of rabbit aorta by hydralazine.
    British journal of pharmacology, 1995, Volume: 114, Issue:1

    Topics: Animals; Aorta; Calcium; Dose-Response Relationship, Drug; Hydralazine; Male; Muscle, Smooth; Phenylephrine; Rabbits; Ryanodine; Sarcoplasmic Reticulum

1995
In vivo correlation of Doppler waveform analysis with arterial input impedance parameters.
    Ultrasound in medicine & biology, 1993, Volume: 19, Issue:7

    Topics: Animals; Animals, Newborn; Aorta, Thoracic; Blood Flow Velocity; Electric Impedance; Hemodynamics; Hydralazine; Phenylephrine; Pulsatile Flow; Reflex; Sheep; Ultrasonography; Vascular Resistance

1993
Characterization of endothelium-dependent vasodilation and vasoconstriction in coronary arteries from spontaneously hypertensive rats.
    American journal of hypertension, 1996, Volume: 9, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Coronary Vessels; Endothelium, Vascular; Heart Rate; Hydralazine; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1996
The alterations of vascular smooth muscle reactivity in vitro by human chorionic gonadotrophin.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1998, Volume: 198, Issue:4

    Topics: Acetylcholine; Animals; Blood Pressure; Chorionic Gonadotropin; Estradiol; Female; Hydralazine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Rats

1998
Angiotensin II receptors within the nucleus of the solitary tract mediate the developmental attenuation of the baroreceptor vagal reflex in pre-weaned rats.
    Journal of the autonomic nervous system, 1998, Dec-11, Volume: 74, Issue:2-3

    Topics: Age Factors; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Antihypertensive Agents; Blood Pressure; Halothane; Heart Rate; Hydralazine; Losartan; Male; Microinjections; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reflex; Solitary Nucleus; Sympathomimetics; Urethane; Vagus Nerve; Weaning

1998
The direct effect of insulin on barosensitive neurones in the nucleus tractus solitarii of rats.
    Neuroreport, 2001, Dec-04, Volume: 12, Issue:17

    Topics: Action Potentials; Animals; Antihypertensive Agents; Blood Glucose; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Glucose; Hydralazine; Insulin; Male; Microinjections; Neurons; Phenylephrine; Pressoreceptors; Rats; Rats, Wistar; Solitary Nucleus; Sympathetic Nervous System; Sympathomimetics

2001
Vasodilator treatment with hydralazine increases blood flow in mdx mice resistance arteries without vascular wall remodelling or endothelium function improvement.
    Journal of hypertension, 2005, Volume: 23, Issue:10

    Topics: Acetylcholine; Animals; Blood Flow Velocity; Blood Pressure; Body Weight; Calcium; Dystrophin; Endothelium, Vascular; Enzyme Inhibitors; Hydralazine; In Vitro Techniques; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mutation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Serotonin; Stress, Mechanical; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2005
Single-unit responses of serotonergic medullary raphe neurons to cardiovascular challenges in freely moving cats.
    The European journal of neuroscience, 2005, Volume: 22, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Behavior, Animal; Cardiovascular Physiological Phenomena; Cats; Electrocardiography; Electromyography; Electrooculography; Heart Rate; Hemorrhage; Hydralazine; Male; Neurons; Nitric Oxide Donors; Nitroprusside; Phenylephrine; Piperazines; Pyridines; Raphe Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep Stages; Vasodilator Agents; Wakefulness

2005
Mechanism of hydralazine-induced relaxation in resistance arteries during pregnancy: Hydralazine induces vasodilation via a prostacyclin pathway.
    Vascular pharmacology, 2016, Volume: 78

    Topics: Animals; Antihypertensive Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Hydralazine; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Pregnancy; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents

2016
pSer40 tyrosine hydroxylase immunohistochemistry identifies the anatomical location of C1 neurons in rat RVLM that are activated by hypotension.
    Neuroscience, 2016, Mar-11, Volume: 317

    Topics: Animals; Antihypertensive Agents; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hybridomas; Hydralazine; Hypotension; Male; Medulla Oblongata; Microarray Analysis; Neurons; Phenylephrine; Pressoreceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serine; Tyrosine 3-Monooxygenase; Vasoconstrictor Agents

2016