hydralazine and nicardipine

hydralazine has been researched along with nicardipine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19906 (19.35)18.7374
1990's8 (25.81)18.2507
2000's10 (32.26)29.6817
2010's4 (12.90)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Amenta, F; Bronzetti, E; Ciriaco, E; Felici, L; Ferrante, F1
Ram, CV1
Ogihara, M; Sunaga, K1
Ogihara, M1
Fujii, S; Kawaguchi, H; Okamoto, H; Saito, H; Togashi, H; Yasuda, H1
Littler, WA; Smith, SA1
Kamei, C; Kurokawa, K; Tasaka, K1
Karasawa, A; Kubo, K; Nakamizo, N; Oka, T; Shuto, K1
Kato, H; Takata, Y1
Adams, ML; Cicero, TJ; Meyer, ER; Sewing, BN1
Benetos, A; Legrand, M; London, GM; Safar, ME; Tsoucaris, D1
Haynes, WG; Webb, DJ1
Abdelwahab, W; Frishman, W; Landau, A1
Kagitani, Y; Kawamura, T; Nagai, H; Nakamura, N; Narita, Y; Shinyama, H1
Amenta, F; Leonardi, A; Sabbatini, M; Testa, R; Vitaioli, L1
Amenta, F; Baldoni, E; Sabbatini, M; Vitaioli, L1
Amenta, F; Leonardi, A; Sabbatini, M; Testa, R; Tomassoni, D; Vitaioli, L1
Arias, ME; Levy, JH; Sato, N; Szlam, F; Tanaka, KA; Tsuda, A1
Marik, PE; Varon, J1
Hao, Q; Liu, W; Marchuk, DA; Rola, R; Su, H; Wang, Y; Yang, GY; Young, WL1
Baldwin, K; McCoy, S1
Cortes, J; Hall, AB; McKay, C1
Dierkhising, RA; Kuper, PJ; Mara, KC; Poyant, JO; Rabinstein, AA; Ritchie, BM; Wijdicks, EFM1
Carrera, JF; Chiota-McCollum, NA; Sorace, BJ; Southerland, AM; Worrall, BB1
Behymer, TP; Bettin, M; Christianson, T; Coleman, ER; Divani, A; Flaherty, ML; Gilkerson, LA; James, ML; King, NKK; Krishnamoorthy, V; Langefeld, CD; McCauley, JL; Ng, Y; Qi, W; Shah, S; Testai, FD; Walsh, KB; Woo, D1
Cho, I; Choe, KR; Jeong, DE; Kim, HJ; Kim, MK; Lee, KN; Park, JY1

Reviews

6 review(s) available for hydralazine and nicardipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Management of hypertensive emergencies: changing therapeutic options.
    American heart journal, 1991, Volume: 122, Issue:1 Pt 2

    Topics: Emergencies; Humans; Hydralazine; Hypertension; Labetalol; Nicardipine; Nitroprusside

1991
Antihypertensive agents--the race for third place.
    Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil

1985
Management of hypertensive urgencies and emergencies.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:8

    Topics: Administration, Oral; Antihypertensive Agents; Emergencies; Enalaprilat; Female; Humans; Hydralazine; Hypertension; Infusions, Parenteral; Labetalol; Nicardipine; Nitroglycerin; Nitroprusside

1995
Perioperative hypertension management.
    Vascular health and risk management, 2008, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Enalaprilat; Fenoldopam; Hemodynamics; Humans; Hydralazine; Hypertension; Incidence; Labetalol; Nicardipine; Nitroglycerin; Nitroprusside; Perioperative Care; Postoperative Complications; Propanolamines; Pyridines; Surgical Procedures, Operative; Vascular Resistance; Vasodilator Agents

2008
Pharmacotherapeutic options for the treatment of preeclampsia.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, Feb-15, Volume: 66, Issue:4

    Topics: Female; Humans; Hydralazine; Magnesium Sulfate; Nicardipine; Nifedipine; Nitroprusside; Pre-Eclampsia; Pregnancy; Risk Factors

2009

Trials

1 trial(s) available for hydralazine and nicardipine

ArticleYear
Initial antihypertensive agent effects on acute blood pressure after intracerebral haemorrhage.
    Stroke and vascular neurology, 2022, Volume: 7, Issue:5

    Topics: Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Humans; Hydralazine; Hypertension; Labetalol; Nicardipine

2022

Other Studies

24 other study(ies) available for hydralazine and nicardipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effect of nicardipine treatment upon cardiac hypertrophy in spontaneously hypertensive rats: a morphometric and ultrastructural study.
    Journal of hypertension, 1992, Volume: 10, Issue:6

    Topics: Animals; Cardiomegaly; Drug Evaluation, Preclinical; Hydralazine; Hypertension; Male; Microscopy, Electron; Myocardium; Nicardipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1992
Effects of calcium channel blockers and hydralazine on plasma glucose levels in streptozotocin-induced diabetic rats in vivo.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:3

    Topics: Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Catecholamines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hexamethonium Compounds; Hydralazine; Male; Nicardipine; Nifedipine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Starvation

1990
Effects of calcium channel blockers and hydralazine on epinephrine-induced hyperglycemia in vivo.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:2

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Epinephrine; Food Deprivation; Glucose Tolerance Test; Hydralazine; Hyperglycemia; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Verapamil

1989
Fatty acid binding protein of cardiac muscle in spontaneously hypertensive rats: effect of hypertrophy and its regression.
    Journal of molecular and cellular cardiology, 1988, Volume: 20, Issue:9

    Topics: Animals; Blood Pressure; Cardiomegaly; Carrier Proteins; Enalapril; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Hydralazine; Hypertension; Male; Myocardium; Neoplasm Proteins; Nerve Tissue Proteins; Nicardipine; Rats; Rats, Inbred SHR

1988
Hypotensive effects of dihydropyridine derivatives.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:9

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hydralazine; Nicardipine; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1985
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in rats.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:11A

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Heart Rate; Hydralazine; Hypertension; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin; Urination

1988
Comparative study on acute antihypertensive effects and pharmacokinetics of nisoldipine, nifedipine, nimodipine and nicardipine administered orally to conscious renal hypertensive dogs.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:10

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hydralazine; Hypertension, Renal; Kinetics; Male; Nicardipine; Nifedipine; Nimodipine; Nisoldipine; Time Factors

1986
Effects of nitric oxide-related agents on rat testicular function.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Drug Interactions; Hydralazine; Isosorbide Dinitrate; Male; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Steroids; Stimulation, Chemical; Testis; Testosterone; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1994
Proximal and distal pulse pressure after acute antihypertensive vasodilating drugs in Wistar-Kyoto and spontaneously hypertensive rats.
    Journal of hypertension, 1995, Volume: 13, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Heart Rate; Hydralazine; Hypertension; Indoles; Male; Nicardipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilator Agents

1995
Venoconstriction to endothelin-1 in humans: role of calcium and potassium channels.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2

    Topics: Adult; Benzopyrans; Calcium Channels; Cromakalim; Diastole; Endothelins; Hand; Humans; Hydralazine; Infusions, Intravenous; Male; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Potassium; Potassium Channels; Pyrroles; Systole; Time Factors; Vasoconstriction; Vasodilator Agents; Veins

1993
Therapeutic effects of AE0047, a novel calcium antagonist, on progression of brain damage after stroke in stroke-prone spontaneously hypertensive rats.
    General pharmacology, 1998, Volume: 30, Issue:3

    Topics: Animals; Brain; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Hydralazine; Male; Nicardipine; Rats; Rats, Inbred SHR; Vasodilator Agents

1998
Effect of calcium antagonists on glomerular arterioles in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:3

    Topics: Albuminuria; Animals; Arterioles; Calcium; Calcium Channel Blockers; Dihydropyridines; Hydralazine; Hypertension, Renal; Juxtaglomerular Apparatus; Male; Nicardipine; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Vasodilator Agents

2000
Nephroprotective effect of treatment with calcium channel blockers in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Hydralazine; Kidney; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Male; Nicardipine; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilator Agents

2000
Effects of dihydropyridine-type Ca2+ antagonists on the renal arterial tree in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:1

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Hydralazine; Kidney; Male; Nicardipine; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Tunica Media; Vasodilator Agents

2002
The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Dopamine; Dose-Response Relationship, Drug; Female; Fenoldopam; Humans; Hydralazine; In Vitro Techniques; Muscle Contraction; Nicardipine; Nitroglycerin; Potassium Chloride; Pre-Eclampsia; Pregnancy; Receptors, Adrenergic, alpha; Thromboxane A2; Umbilical Arteries; Vasoconstrictor Agents; Vasodilator Agents

2003
Increased tissue perfusion promotes capillary dysplasia in the ALK1-deficient mouse brain following VEGF stimulation.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:6

    Topics: Activin Receptors, Type I; Activin Receptors, Type II; Animals; Brain; Capillaries; Cerebrovascular Circulation; Dependovirus; Disease Models, Animal; Genetic Vectors; Hydralazine; Imaging, Three-Dimensional; Infusions, Parenteral; Intracranial Arteriovenous Malformations; Male; Mice; Mice, Knockout; Microcirculation; Microscopy, Confocal; Neovascularization, Physiologic; Nicardipine; Transduction, Genetic; Vascular Endothelial Growth Factor A; Vasodilator Agents

2008
Time to Blood Pressure Control Before Thrombolytic Therapy in Patients With Acute Ischemic Stroke: Comparison of Labetalol, Nicardipine, and Hydralazine.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 2015, Volume: 47, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Female; Fibrinolytic Agents; Humans; Hydralazine; Hypertension; Infusions, Intravenous; Labetalol; Male; Middle Aged; Nicardipine; Retrospective Studies; Stroke; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator

2015
Nicardipine Reduces Blood Pressure Variability After Spontaneous Intracerebral Hemorrhage.
    Neurocritical care, 2019, Volume: 30, Issue:1

    Topics: Administration, Intravenous; Adult; Aged; Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Female; Humans; Hydralazine; Labetalol; Male; Middle Aged; Nicardipine; Retrospective Studies; Treatment Outcome

2019
Delay to Tissue Plasminogen Activator in Hypertensive Stroke Patients: An Analysis of Delay Duration Across Agents.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:2

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Female; Fibrinolytic Agents; Humans; Hydralazine; Hypertension; Infusions, Intravenous; Labetalol; Male; Nicardipine; Retrospective Studies; Stroke; Thrombolytic Therapy; Time Factors; Time-to-Treatment; Tissue Plasminogen Activator; Treatment Outcome

2020
Use of continuous infusion of nicardipine to control persistent postpartum hypertension: A retrospective study.
    Medicine, 2022, Dec-23, Volume: 101, Issue:51

    Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Labetalol; Nicardipine; Postpartum Period; Pregnancy; Retrospective Studies

2022