Compounds > hydralazine

hydralazine and melphalan

hydralazine has been researched along with melphalan in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (25.00)	18.7374
1990's	2 (16.67)	18.2507
2000's	4 (33.33)	29.6817
2010's	3 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bibby, MC; Cox, JA; Crawford, SM; Quinn, PK	1
Siemann, DW	1
Acker, B; Chaplin, DJ; Olive, PL	1
Adams, GE; Godden, J; Howells, N; Stratford, IJ	1
Adams, GE; Godden, J; Howells, N; Nolan, J; Stratford, IJ; Timpson, N	1

Reviews

1 review(s) available for hydralazine and melphalan

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

11 other study(ies) available for hydralazine and melphalan

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
The influence of hydralazine on the vasculature, blood perfusion and chemosensitivity of MAC tumours. British journal of cancer, 1992, Volume: 66, Issue:2 Topics: Adenocarcinoma; Animals; Bone Marrow; Cell Division; Cell Line; Colonic Neoplasms; Hydralazine; Male; Melphalan; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Radionuclide Imaging; Regional Blood Flow; Taurine; Tumor Stem Cell Assay	1992
Enhancement of chemotherapy and nitroimidazole-induced chemopotentiation by the vasoactive agent hydralazine. British journal of cancer, 1990, Volume: 62, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cyclophosphamide; Drug Synergism; Female; Hydralazine; Lomustine; Melphalan; Mice; Mice, Inbred C3H; Misonidazole; Sarcoma, Experimental; Stem Cells	1990
Potentiation of the tumor cytotoxicity of melphalan by vasodilating drugs. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Drug Synergism; Drug Therapy, Combination; Female; Hydralazine; Melphalan; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Pyridazines; Vasodilator Agents	1989
Enhancement of the anti-tumor effect of melphalan in experimental mice by some vaso-active agents. International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5 Topics: Animals; Drug Synergism; Drug Therapy, Combination; Hydralazine; Melphalan; Mice; Neoplasms, Experimental; Nifedipine; Vasodilator Agents; Verapamil	1989
Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine. British journal of cancer, 1988, Volume: 58, Issue:2 Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Hydralazine; Male; Melphalan; Mice; Mice, Inbred C3H; Misonidazole; Oxygen Consumption; Sarcoma, Experimental; Time Factors	1988