hydralazine and isradipine

hydralazine has been researched along with isradipine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's6 (40.00)18.2507
2000's4 (26.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hof, A; Hof, RP; Takiguchi, Y1
Christensen, KL1
Atkinson, J; Bentahila, S; Capdeville, C1
Christensen, KL; Jespersen, LT; Mulvany, MJ1
Baandrup, U; Christensen, HR; Christensen, KL; Jespersen, LT; Nielsen, H1
Evenou, JP; Hof, RP; Hof-Miyashita, A1
Aalkjaer, C; Holm, M; Lederballe, O; Mulvany, M; Mørn, B; Schroeder, AP; Sihm, I; Thygesen, K1
Abbate, F; Amenta, F; Ciriaco, E; Ferrante, F; Laurà, R1
Bachelard, H; Gaudreault, N; Nadeau, A; Pĭtre, M; Santuré, M1
de Moura, RS; Ferraz, MM; Ferraz, MR; Santos, R1

Reviews

1 review(s) available for hydralazine and isradipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for hydralazine and isradipine

ArticleYear
Normalization of structural cardiovascular changes during antihypertensive treatment with a regimen based on the ACE-inhibitor perindopril.
    Blood pressure, 1995, Volume: 4, Issue:4

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Indoles; Isradipine; Male; Middle Aged; Perindopril; Vascular Resistance

1995

Other Studies

13 other study(ies) available for hydralazine and isradipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparative hemodynamic studies of isradipine and dihydralazine in atherosclerotic and normal rabbits.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 1

    Topics: Animals; Arteriosclerosis; Calcium Channel Blockers; Coronary Artery Disease; Dihydralazine; Electrocardiography; Hemodynamics; Hydralazine; Isradipine; Microspheres; Pyridines; Rabbits; Regional Blood Flow

1990
Reducing pulse pressure in hypertension may normalize small artery structure.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:6

    Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Captopril; Dihydropyridines; Heart Rate; Hydralazine; Hypertension; Indoles; Isradipine; Male; Metoprolol; Perindopril; Pulse; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regression Analysis

1991
Protective effects of antihypertensive treatment with isradipine on the consequences of cerebral ischaemia in the spontaneously hypertensive rat.
    Journal of hypertension, 1991, Volume: 9, Issue:2

    Topics: Animals; Antihypertensive Agents; Brain Ischemia; Hydralazine; Hypertension; Isradipine; Male; Motor Activity; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains

1991
Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure.
    Journal of hypertension, 1989, Volume: 7, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hydralazine; Hypertension; Indoles; Isradipine; Male; Mesenteric Arteries; Mesenteric Veins; Metoprolol; Perindopril; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance

1989
Antitrophic properties of antihypertensive drugs may depend solely on their blood pressure-lowering capability. A comparative study of isradipine, hydralazine, and metoprolol.
    The American journal of medicine, 1989, Apr-17, Volume: 86, Issue:4A

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Coronary Vessels; Hydralazine; Isradipine; Male; Metoprolol; Pyridines; Rats; Rats, Inbred SHR; Vascular Resistance

1989
Similar increase in circulating renin after equihypotensive doses of nitroprusside, dihydralazine or isradipine in conscious rabbits.
    European journal of pharmacology, 1987, Apr-14, Volume: 136, Issue:2

    Topics: Animals; Calcium Channel Blockers; Dihydralazine; Female; Ferricyanides; Hemodynamics; Hydralazine; Isradipine; Male; Nitroprusside; Oxadiazoles; Rabbits; Renin

1987
Influence of isradipine treatment on the morphology of the aorta in spontaneously hypertensive rats.
    Journal of hypertension, 1994, Volume: 12, Issue:5

    Topics: Animals; Aorta; Blood Pressure; Hydralazine; Hypertension; Isradipine; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1994
Isradipine and insulin sensitivity in hypertensive rats.
    The American journal of physiology, 1999, Volume: 276, Issue:6

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glucose Clamp Technique; Hemodynamics; Hydralazine; Hypertension; Insulin; Isradipine; Male; Rats; Rats, Inbred SHR; Renal Circulation; Vasoconstrictor Agents; Vasodilator Agents

1999
Preventing L-NAME inhibitory effects on rat sexual behavior with hydralazine, isradipine or captopril co-treatment.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Captopril; Drug Interactions; Ejaculation; Enzyme Inhibitors; Female; Hydralazine; Isradipine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sexual Behavior, Animal; Time Factors; Vasodilator Agents

2003