hydralazine has been researched along with hydrochlorothiazide in 221 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 162 (73.30) | 18.7374 |
| 1990's | 26 (11.76) | 18.2507 |
| 2000's | 21 (9.50) | 29.6817 |
| 2010's | 12 (5.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cherkez, S; Herzig, J; Yellin, H | 1 |
| Baer, JE; Cragoe, EJ; Deana, AA; deSolms, SJ; Ludden, CT; Russo, HF; Schultz, EM; Scriabine, A; Smith, RL; Stokker, GE; Sweet, CS; Watson, LS | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Andersson, O; Hansson, L; Sivertsson, R | 1 |
| Alimadadian, H; Aronow, WS; Burwell, D; Greenfield, R; Mann, W; Van Herick, R | 1 |
| Németh, M; Pár, A; Tényi, I | 1 |
| Arias, F; Zamora, J | 1 |
| Antonaccio, MJ; Horovitz, ZP; Panasevich, RE; Rubin, B | 1 |
| Panikarskiĭ, VG | 2 |
| Barofsky, I; Kresel, JJ | 1 |
| Ambrosio, G; Corgnati, A; Dal Palù, C; Palatini, P; Pessina, AC | 1 |
| Ebel, H; Klaus, D; Lübke, H; Witzgall, H; Zehner, J | 1 |
| Araoye, MA; Freis, ED; Khatri, IM; Yao, LL | 1 |
| David, NA; Pierce, HI; Welborn, WS | 1 |
| Hollander, W; Kirkpatrick, B; Madoff, I; Paddock, J | 1 |
| Eddleman, EE | 1 |
| Jones, AW; Kampschmidt, DL; Sander, PD | 1 |
| Blaik, R | 1 |
| Grim, CE | 1 |
| Aldrete, JS; Diethelm, AG; Hartley, MW; Morgan, JM; Sterling, WA | 1 |
| Freis, ED; Taguchi, J | 2 |
| Alderman, MH; Schoenbaum, EE | 1 |
| Ferguson, HC; McKinney, GR; Perhach, JL | 1 |
| Freis, ED | 6 |
| Danilevicius, Z | 1 |
| Hamilton, TC | 1 |
| Dück, KD | 1 |
| Keidan, H | 1 |
| Cohen, JD | 1 |
| Allen, TJ; Cooper, ME; Doyle, AE; Jerums, G; O'Brien, RC; Rumble, JR | 1 |
| Baumbach, GL; Fujii, K; Heistad, DD; Weno, BL | 1 |
| Rahn, KH | 1 |
| Glezer, GA; Levinzon, AM; Moskalenko, NP | 1 |
| Ambrosioni, E; Cinotti, G; Cuspidi, C; Leonetti, G; Malini, PL; Morabito, S; Pessina, A; Rappelli, A; Sampieri, L; Semplicini, A | 1 |
| Wang, W | 1 |
| Diakos, A; Kontoyannis, DA; Kontoyannis, SA; Moulopoulos, SD; Sideris, DA | 1 |
| Canby, CA; Tomanek, RJ | 1 |
| Dworkin, LD; Feiner, HD; Grosser, M; Parker, M; Ullian, M | 1 |
| Fogo, A; Ichikawa, I; Ikoma, M; Kawamura, T; Yoshida, Y | 1 |
| Anderson, S; Brenner, BM; Garcia, DL; Rennke, HG | 1 |
| Beyrich, T; Feldmeier, HG; Herberg, H | 1 |
| Al'khimovich, VM; Gaĭduk, VN; Nechesova, TA; Pavlova, AI; Sidorenko, GI | 1 |
| Löllgen, H; Schmidt, A; Upmeyer, HJ | 1 |
| Hedner, T | 1 |
| Waters, VV | 1 |
| Franklin, SS; Smith, RD | 2 |
| Chiou, XC; Owens, R; Raij, L; Wrigley, B | 1 |
| Anderson, S; Brenner, BM; Rennke, HG | 1 |
| Sullivan, JM | 1 |
| Anshelevich, IuV; Dumesh, SZ; Itskovich, VS; Orlova, VP; Raĭbaert, IaIa | 1 |
| Byyny, RL; LoVerde, ME; Mitchell, WD; Nies, AS | 1 |
| Bruner, CA; Webb, RC | 1 |
| Akintonwa, DA | 1 |
| Sano, T; Tarazi, RC | 1 |
| Bohr, DF; Soltis, EE | 1 |
| Dworkin, LD; Feiner, HD; Randazzo, J | 1 |
| Baldwin, DS; Feiner, H; Kaminetsky, B; Liu, DT; Neugarten, J; Schacht, RG | 1 |
| Bobrov, VA; Fushteĭ, IM; Ianushevskaia, TA; Polipova, SN | 1 |
| Freis, ED; Kyle, MC | 1 |
| Challoner-Hue, L; Gottstein, JH; Steele, TH | 1 |
| Blomqvist, CG; Gaffney, FA; Graham, RM; Mulvihill-Wilson, J; Neal, WW; Pettinger, WA | 1 |
| Chidsey, CA | 1 |
| Jänne, J; Keyriläinen, O; Koskinen, P; Leskinen, O; Pitkäjärvi, T; Reinikainen, M; Siitonen, L | 1 |
| Fulghum, JE; Groover, ME; Simpson, WG | 1 |
| Freis, ED; Kyle, MC; Pipberger, HV; Poblete, PF | 1 |
| Chidsey, CA; Gottlieb, TB; Katz, FH | 1 |
| Pettinger, WA | 1 |
| Moser, M | 1 |
| Raper, AJ | 1 |
| Clark, GM; Troop, RC | 1 |
| Chasis, H | 1 |
| Laidlaw, JC | 1 |
| Siegler, RL | 1 |
| Finch, L | 1 |
| Glazer, N | 1 |
| Carstens, E | 1 |
| Freis, ED; Limas, CJ | 1 |
| Kim, KE; Onesti, G; Swartz, C | 1 |
| Finnerty, FA | 1 |
| Haller, J | 1 |
| Hesse, E; Lang, O | 1 |
| Lamid, S; Wolff, FW | 1 |
| Kashnir, VS | 1 |
| Fishback, DB | 1 |
| Ahearn, DJ; Grim, CE | 1 |
| Aoki, VS; Wilson, WR | 1 |
| Conway, J; Sannerstedt, R | 1 |
| Kiesenwetter, R | 1 |
| Ausubel, H; Levine, ML | 1 |
| O'Connell, A; Urbányi, T | 1 |
| Froment, A; Milon, H | 1 |
| Rehm, CR; Slone, TJ; Urbanyi, T | 1 |
| Babei, E; Enescu, I; Friedman, R; Tacu, V | 1 |
| Freyland, MD; Frotscher, U; Messerschmidt, W; Piehl, W; Wilbrandt, R | 1 |
| Fritz, KW; Steinbuch, HJ | 1 |
| Campus, G; Pavesi, V | 1 |
| Dalvi, CP; Datey, KK; Deshmukh, SN | 1 |
| Pomerantz, HZ | 2 |
| Zanchetti, A | 1 |
| Gervasini, N; Repetto, S; Rezzonico, A | 1 |
| Tanney, H | 1 |
| Ceino, A; Vizioli, A | 1 |
| Tretenhahn, W | 1 |
| Soyka, LF | 1 |
| Ferrario, G; Natangelo, R | 1 |
| Cooper, CM; Stanton, HC | 1 |
| Richter, R | 1 |
| Bartsch, W; Glocke, M; Häcker, W; Teufel, W | 1 |
| Antonaccio, MJ; Cheung, HS; Cushman, DW; Murthy, VS; Ondetti, MA; Rubin, B | 1 |
| Julius, S; Nicholls, MG; Zweifler, AJ | 1 |
| Fernandez, PG; Galway, AB; Kim, BK | 1 |
| Carr, AA | 1 |
| Parashchak, AP; Ryzhova, VL; Shvedenko, LA | 1 |
| Moyer, JH | 1 |
| Dols, DM; Houtzagers, JJ; Meems, L | 1 |
| Eninia, GI; Godlevska, MA; Smeltere, ES; Uzulinia, IP | 1 |
| Bigar', PV; Kozak, VP; Man'ko, VI; Parashchak, AP; Shvedenko, LA | 1 |
| Jounela, AJ; Karppanen, H; Salmela, PI | 1 |
| Gerasimenko, NI; Iurkevich, ST; Kozak, VP; Nikulin, KE; Shvedenko, LA; Vakaliuk, PM | 1 |
| Bigar', PV; Iurkevich, ST; Neporadnyĭ, MD; Parashchak, AP; Shvedenko, LA | 1 |
| Perry, HM | 1 |
| Alexander, JC; Burke, JF; Ferguson, RK; Koplin, JR; Shirinian, A; Vlasses, PH | 1 |
| Antonaccio, MJ; Horovitz, ZP; Rubin, B | 1 |
| Honkavaara, M; Nissinen, A; Tuomilehto, J | 1 |
| Jalonen, K; Pörsti, P; Ryysy, L; Toivonen, T; Viherkoski, M | 1 |
| Lüscher, T; Siegenthaler, W; Studer, A; Vetter, W | 1 |
| Freis, E | 1 |
| Ilika, VG; Iurkevich, ST; Nikulin, KE; Shvedenko, LA; Vakaliuk, PM | 1 |
| Spence, JD | 1 |
| Prisiazhniuk, MS; Shchepotin, BM; Shchulipenko, IM | 1 |
| García Sacristán, A | 1 |
| Traub, O; Webb, RC | 1 |
| Naish, PF; Odum, J; Purkiss, J | 1 |
| Aurell, M; Berglund, G; Hartford, M; Lindstedt, G; Ljungman, S; Wikstrand, J | 1 |
| Mahnensmith, RL | 1 |
| Baba, N; Sakemi, T | 1 |
| Cooper, ME; Doyle, AE; Jerums, G; O'Brien, RC | 1 |
| Lloyd, MC; Traub, O; Webb, RC | 1 |
| Cooper, M; Gin, T; Jerums, G; Joon, TL; Panagiotopoulos, S; Taylor, H | 1 |
| Benediktsson, H; Muralidharan, J; Paul, L | 1 |
| Fukui, M; Sekizuka, K; Shirato, I; Shou, I; Suzuki, S; Tomino, Y; Wang, LN; Yamamoto, M | 1 |
| Fukui, M; Shou, I; Takahashi, Y; Tomino, Y; Wang, LN | 1 |
| Fukui, M; Shou, I; Tang, Z; Tomino, Y; Wang, LN | 1 |
| Abraham, AA; Michaelis, OE; Scalbert, E; Striffler, JS; Thibault, N; Velasquez, MT | 1 |
| Fukui, M; Shou, I; Suzuki, S; Tomino, Y; Wang, LN | 1 |
| Helmchen, U; Schneider, A; Stahl, RA; Wenzel, U; Wolf, G | 1 |
| Anderson, NH; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; Morton, JJ; Reid, JL; Schork, NJ | 1 |
| Benedetti, G; Benigni, A; Bruzzi, I; Corna, D; Noris, M; Remuzzi, G; Todeschini, M; Zoja, C | 1 |
| Brosnan, MJ; Clark, JS; Devlin, AM; Dominiczak, AF; Mullins, JJ | 1 |
| Bader, M; Breu, V; Ganten, D; Gross, V; Haller, H; Luft, FC; Mervaala, E; Müller, DN; Park, JK; Schmidt, F | 1 |
| Armini, L; Bardelli, M; Calci, M; Campanacci, L; Candido, R; Carretta, R; Fabris, B; Fazio, M; Fischetti, F | 1 |
| Abe, I; Fujii, K; Fujishima, M; Goto, K; Onaka, U | 1 |
| Welch, WJ; Wilcox, CS | 1 |
| Abe, I; Kagiyama, S; Lin, Y; Matsumura, K; Tsuchihashi, T | 1 |
| Bi, WF; Chang, NC; Lai, ZY; Lin, MS; Shih, CM; Wang, TC | 1 |
| Adams, MA; Bushfield, TL; Hale, TM; Woolard, J | 1 |
| HOPFGARTNER, A | 1 |
| DUCRET, S | 1 |
| GALLI, G | 1 |
| ANGHEL, E; CIMPEANU, S; NICOLAESCU, V; SIRBULESCU, R; TEODORESCU, P | 1 |
| HOBBS, LF | 1 |
| DOCHEV, D; POPOV, NG | 1 |
| OKADA, R; SHINTANI, F; TAKEDA, T; TAKEUCHI, J; UCHIDA, E | 1 |
| SPAULDING, WB | 1 |
| MIRONOV, P; VAPTSAROV, A | 1 |
| KAMAL, I | 1 |
| FAVERO, S; SANCHETTI, P | 1 |
| BELSITO, F; LONGARETTI, A | 1 |
| KINOSHITA, Y; YAMADA, A | 1 |
| GELFAND, MD; OKUN, R; WILSON, WR | 1 |
| ORGAIN, ES; SASSEN, FA; SHELBURNE, PF | 1 |
| BOETTIGER, LE; MALMBORG, RO; MICHAELI, EW | 1 |
| CLEJ, V; ENESCU, R; MIHAILESCU, VV; SBENGHE, S | 1 |
| CHUPKOVICH, V; FINNERTY, FA; KAKAVIATOS, N | 1 |
| SCHULTZ, FB | 1 |
| HAHN, R; KONG, Y; TAN, CH | 1 |
| DOMINGUEZ, GH; ROWLAND, W | 1 |
| BELONOSCHKIN, B | 1 |
| BELLUSCHI, A; VACCHINI, V | 1 |
| LATTA, H; LITMAN, N; SMITH, FG | 1 |
| Bidani, AK; Griffin, KA; Picken, MM | 1 |
| Alonso, C; Catalán, MP; Egido, J; Gallego-Delgado, J; Gómez-Garre, D; Largo, R; Ortiz, A; Plaza, JJ; Soto, K; Tejera, N | 1 |
| Cook, AK; Imig, JD; Inscho, EW; Murzynowski, JB | 1 |
| Bayraktutan, U; Demirci, B; McKeown, PP | 1 |
| Bell, D; Devine, AB; McDermott, BJ; McHenry, EM; Nicholls, DP; Smith, LR; Zhao, L; Zhao, Y | 1 |
| Adams, MA; Hale, TM; Hannan, JL; Heaton, JP; Smallegange, C | 1 |
| Agharazii, M; Larivière, R; Lebel, M; Rodrigue, ME | 1 |
| Biswas, SK; de Faria, JB; de Faria, JM; Pinto, CC; Silva, KC; Souza, DS | 1 |
| Leong, PK; McDonough, AA; Yang, LE | 1 |
| Amann, K; Hartner, A; Hilgers, KF; Klanke, B; Melk, A; Steinbach, MP; Westhoff, JH | 1 |
| Cordasic, N; Hartner, A; Hilgers, KF; Klanke, B; Schmieder, RE; Veelken, R | 1 |
| Araki, S; Hirooka, Y; Kishi, T; Sunagawa, K; Utsumi, H; Yasukawa, K | 1 |
| d'Uscio, LV; Kang, KT; Katusic, ZS; Pollock, JS; Spradley, FT; Sullivan, JC | 1 |
| Lin, JY; Moens, AL | 1 |
| Aderibigbe, A; Anisiuba, BC; Ba, SA; Boombhi, HJ; Ijoma, CK; Kamdem, MK; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, AN; Omotoso, BA; Richart, T; Staessen, JA; Thijs, L; Ulasi, II | 1 |
| Fan, X; Harris, RC; Takahashi, T; Wang, S; Yang, H; Yang, S; Zhang, MZ | 1 |
| Hara, T; Hayden, MR; Hitomi, H; Ichimura, A; Ito, S; Kaifu, K; Kawachi, H; Kiyomoto, H; Kobori, H; Kohno, M; Matsumoto, S; Nishijima, Y; Nishiyama, A; Ohsaki, H; Sofue, T; Sowers, JR; Urushihara, M; Whaley-Connell, A | 1 |
| Boor, P; Cohen, CD; Denecke, B; Eitner, F; Floege, J; Gan, L; Konieczny, A; Kunter, U; Neusser, MA; Ostendorf, T; Scholl, T; van Roeyen, CR; Villa, L | 1 |
| Bidani, AK; Griffin, KA; Litbarg, N; Picken, M; Polichnowski, A; Venkatachalam, MA | 1 |
| Capdevila, JH; Falck, JR; Gangadhariah, MH; Garcia, V; Hayward, SW; Imig, JD; Love, HD; Luther, JM; Manthati, VL; Paueksakon, P; Pozzi, A; Schwartzman, ML; Zent, R; Zhang, MZ | 1 |
| Dorrance, AM; Jackson, WF; Pires, PW | 1 |
| Cha, H; Cook, AK; Guan, Z; Inscho, EW; Pollock, DM; Pollock, JS; Singletary, ST; Van Beusecum, JP | 1 |
10 review(s) available for hydralazine and hydrochlorothiazide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Effectiveness of drug therapy in hypertension: present status. A review.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Coronary Disease; Eye Diseases; Ganglionic Blockers; Guanethidine; Heart Failure; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Myocardial Infarction; Placebos; Prognosis; Reserpine; Retina; Uremia | 1971 |
The treatment of hypertension. Why, when and how.
Topics: Arteriosclerosis; Cardiovascular Diseases; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Methyldopa; Phytotherapy; Plants, Medicinal; Prospective Studies; Rauwolfia; Reserpine; Time Factors | 1972 |
[Use and abuse of antihypertensive drugs in the treatment of elderly patients].
Topics: Age Factors; Aged; Antihypertensive Agents; Cardiac Output; Diuretics; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Methods; Methyldopa; Phytotherapy; Plants, Medicinal; Potassium; Rauwolfia; Sex Factors; Sodium; Time Factors; Vascular Resistance | 1970 |
[Side effects of antihypertensive therapy].
Topics: Acetazolamide; Antihypertensive Agents; Blood Pressure; Furosemide; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Imidazoles; Monoamine Oxidase Inhibitors; Plants, Medicinal; Propranolol; Propylamines; Rauwolfia; Reserpine; Secologanin Tryptamine Alkaloids; Vertigo; Water-Electrolyte Balance | 1970 |
Hypertension--low cost chemotherapy.
Topics: Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1983 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Methyldopa; Patient Compliance; Prazosin; Proteinuria; Renin-Angiotensin System; Reserpine; Spironolactone | 1984 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Dogs; Hemodynamics; Hydralazine; Hydrochlorothiazide; Hypertension; Kallikreins; Kidney; Proline; Prostaglandins; Rabbits; Rats; Renin; Sodium | 1980 |
Diabetic nephropathy: a comprehensive approach.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Clinical Protocols; Clinical Trials as Topic; Counseling; Diabetic Nephropathies; Drug Evaluation, Preclinical; Drug Therapy, Combination; Glomerular Filtration Rate; Hydralazine; Hydrochlorothiazide; Insulin; Patient Care Planning; Rats; Reserpine; Risk Factors; Sensitivity and Specificity; Severity of Illness Index | 1993 |
[ANTIHYPERTENSIVE DRUGS].
Topics: Antihypertensive Agents; Bretylium Compounds; Chlorothiazide; Ganglionic Blockers; Guanethidine; Hydralazine; Hydrochlorothiazide; Hydroflumethiazide; Methyldopa; Rauwolfia; Sympatholytics; Trichlormethiazide; Veratrum; Veratrum Alkaloids | 1963 |
36 trial(s) available for hydralazine and hydrochlorothiazide
| Article | Year |
|---|---|
Propranolol in the treatment of essential hypertension.
Topics: Adolescent; Adult; Blood Pressure; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Propranolol; Reserpine; Vascular Resistance | 1977 |
Effect of timolol plus hydrochlorothiazide plus hydralazine on essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Propanolamines; Timolol | 1978 |
Nepresol in the treatment of hypertension of major severity.
Topics: Adult; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Propranolol; Sodium | 1979 |
[Treatment of essential hypertension with a combination of propranolol, spironolactone-thiabutazide and dihydralazine (author's transl)].
Topics: Anxiety; Bradycardia; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Paresthesia; Potassium; Propranolol; Renin; Spironolactone | 1978 |
Comparison of multiple and combination tablet drug therapy in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine; Time Factors | 1975 |
Partial versus complete control of blood pressure in the prevention of hypertensive complications.
Topics: Atrial Fibrillation; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-Up Studies; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Intracranial Embolism and Thrombosis; Male; Myocardial Infarction; Reserpine | 1975 |
Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study.
Topics: Blood Pressure; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Multicenter Studies as Topic; Propranolol; Randomized Controlled Trials as Topic | 1990 |
[Double-blind comparison of fixed combination preparations of a beta blocker and a diuretic and beta blocker, a diuretic and hydralazine in patients with coronary heart disease and arterial hypertension].
Topics: Adrenergic beta-Antagonists; Aged; Amiloride; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Random Allocation | 1986 |
Clinical evaluation of felodipine in hypertensive patients previously treated with a triple drug regimen.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Nitrendipine | 1987 |
Comparison of effects of enalapril plus hydrochlorothiazide versus standard triple therapy on renal function in renovascular hypertension.
Topics: Adult; Aged; Blood Pressure; Enalapril; Female; Glomerular Filtration Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Renovascular; Kidney; Male; Middle Aged; Renal Circulation; Timolol | 1985 |
A comparison of enalapril plus hydrochlorothiazide with standard triple therapy in renovascular hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Renovascular; Kidney; Male; Middle Aged; Patient Dropouts; Prospective Studies; Random Allocation; Timolol | 1986 |
A double-blind, randomized, controlled trial comparing pinacidil to hydralazine in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Epinephrine; Female; Guanidines; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Male; Middle Aged; Norepinephrine; Pinacidil; Propranolol; Random Allocation; Renin | 1987 |
Single and combined therapy for systemic hypertension with propranolol, hydralazine and hydrochlorothiazide: hemodynamic and neuroendocrine mechanisms of action.
Topics: Adult; Drug Therapy, Combination; Exercise Test; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension, Orthostatic; Male; Middle Aged; Neurosecretory Systems; Posture; Propranolol; Vascular Resistance | 1985 |
Clinical and pharmacokinetic studies of minoxidil, a new antihypertensive agent.
Topics: Adrenergic beta-Antagonists; Amino Alcohols; Antihypertensive Agents; Carbon Isotopes; Clinical Trials as Topic; Diazoxide; Drug Combinations; Humans; Hydralazine; Hydrochlorothiazide; Minoxidil; Piperidines; Pyrimidines; Time Factors | 1973 |
Hydralazine and beta-adrenergic blockade in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxprenolol; Placebos | 1974 |
Effect of treatment on morbidity in hypertension. Veterans Administration Cooperative Study on Antihypertensive Agents. Effect on the electrocardiogram.
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Electrocardiography; Heart Block; Heart Conduction System; Heart Ventricles; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Placebos; Reserpine; United States | 1973 |
Effects of treatment on morbidity in hypertension. 3. Influence of age, diastolic pressure, and prior cardiovascular disease; further analysis of side effects.
Topics: Adult; Age Factors; Aged; Aneurysm; Atrial Fibrillation; Blood Glucose; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Glomerulonephritis; Heart Failure; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Morbidity; Reserpine; Sampling Studies; Uric Acid | 1972 |
One-tablet combination drug therapy in the treatment of hypertension.
Topics: Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Dosage Forms; Drug Combinations; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Potassium; Pulse; Reserpine; Tablets; Uric Acid | 1972 |
Appraisal of antihypertensive drug therapy.
Topics: Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Intracranial Embolism and Thrombosis; Male; Mass Screening; Middle Aged; Myocardial Infarction; Placebos; Prospective Studies; Reserpine; Retinal Diseases; United States; United States Department of Veterans Affairs; Vascular Diseases | 1974 |
Partial reduction of blood pressure and prevention of complications in hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Follow-Up Studies; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Reserpine | 1974 |
Hypertension: a challenge in preventive medicine.
Topics: Age Factors; Attitude to Health; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Drug Combinations; Heart Failure; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Mass Screening; Middle Aged; North America; Reserpine; Time Factors | 1974 |
Reserpine, hydralazine, hydrochlorothiazide combination (Ser-AP-ES) in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Computers; Drug Combinations; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Middle Aged; Nausea; Placebos; Pulse; Reserpine | 1972 |
Hydralazine and methyldopa in thiazide-treated hypertensive patients.
Topics: Black People; Clinical Trials as Topic; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Placebos; White People | 1970 |
Effect of treatment on morbidity and mortality in hypertension.
Topics: Age Factors; Black or African American; Blood Pressure; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Insurance, Life; Male; Middle Aged; Morbidity; Placebos; Reserpine; Sex Factors | 1971 |
[Medical treatment of arterial hypertension].
Topics: Antihypertensive Agents; Diuretics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Reserpine | 1971 |
[Therapeutic equivalent of a single and divided daily dose of 2 Tri-Torrat coated tablets].
Topics: Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Metipranolol; Middle Aged; Propanolamines; Tablets, Enteric-Coated | 1984 |
Veterans Administration cooperative study on nadolol as monotherapy and in combination with a diuretic.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Bendroflumethiazide; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Oxprenolol; Propanolamines; Propranolol; Random Allocation; Renin; United States; United States Department of Veterans Affairs | 1984 |
An appraisal of antihypertensive efficacy and adverse reactions with two drug regimens: enalapril maleate as part of triple therapy compared to conventional triple therapy in moderate to severe hypertension.
Topics: Adult; Antihypertensive Agents; Clinical Trials as Topic; Dipeptides; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol | 1984 |
[Treatment of hypertensive patients with adelphan-esidrex].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1983 |
Double-blind comparison of dihydralazine and prazosin in hypertensive patients on the diuretic-reserpine regimen.
Topics: Adult; Aged; Clinical Trials as Topic; Dihydralazine; Double-Blind Method; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Prazosin; Quinazolines; Renin; Reserpine; Triamterene | 1981 |
Clinical evaluation of the antihypertensive effect of metoprolol in combination with hydrochlorothiazide and hydralazine in an unselected hypertensive population.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cholesterol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Lipids; Male; Metoprolol; Middle Aged; Propanolamines | 1980 |
Antihypertensive action of drug combination: Timolol, hydralazine, hydrochlorothiazide and triamterene.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propanolamines; Random Allocation; Timolol; Triamterene | 1981 |
Comparison of prazosin with hydralazine in patients receiving hydrochlorothiazide. A randomized, double-blind clinical trial.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pulse; Quinazolines; Random Allocation | 1981 |
[Current state of the treatment of arterial hypertension].
Topics: Adult; Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Heart Failure; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Middle Aged; Myocardial Infarction; Random Allocation; Reserpine; United States | 1980 |
Fosinopril improves left ventricular diastolic function in young mildly hypertensive patients without hypertrophy.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Echocardiography, Doppler; Female; Fosinopril; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Reference Values; Time Factors; Ventricular Function, Left | 2002 |
Rationale and design of the Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial.
Topics: Adult; Africa South of the Sahara; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Research Design; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
175 other study(ies) available for hydralazine and hydrochlorothiazide
| Article | Year |
|---|---|
Synthesis, saludiuretic, and antihypertensive activity of 6,7-disubstituted 1(2H)- and 3,4-dihydro-1(2H)-phthalazinones.
Topics: Animals; Antihypertensive Agents; Diuretics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Rats; Rats, Inbred SHR; Sodium Chloride; Structure-Activity Relationship | 1986 |
2-(Aminomethyl)phenols, a new class of saluretic agents. 1. Effects of nuclear substitution.
Topics: Administration, Oral; Animals; Chemical Phenomena; Chemistry; Diuretics; Dogs; Female; Injections, Intravenous; Natriuresis; Phenols; Rats; Structure-Activity Relationship | 1980 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Primary hypertension refractory to triple drug treatment - a study on central and peripheral hemodynamics.
Topics: Bendroflumethiazide; Drug Therapy, Combination; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Propranolol | 1979 |
Antihypertensive treatment and pregnancy outcome in patients with mild chronic hypertension.
Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Fetal Growth Retardation; Fetus; Growth; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Infant, Newborn; Methyldopa; Oxytocin; Pregnancy; Pregnancy Complications, Cardiovascular; Prenatal Diagnosis; Ultrasonography | 1979 |
Influence of various antihypertensive agents on lifespan of renal hypertensive rats.
Topics: Animals; Blood Pressure; Disease Models, Animal; Diuretics; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Male; Proline; Rats; Sodium Chloride Symporter Inhibitors | 1979 |
[Use of Adelphan-Esidrex in treating hypertension].
Topics: Adult; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine; Tablets | 1979 |
Conditioned saccharin aversion development following administration of hypotensive agents.
Topics: Animals; Antihypertensive Agents; Avoidance Learning; Conditioning, Classical; Drinking; Extinction, Psychological; Hydralazine; Hydrochlorothiazide; Male; Methyldopa; Rats; Saccharin; Taste | 1979 |
[Long-term treatment of arterial hypertension with propranolol. Combination with diuretics and dihydrazinophthalazine].
Topics: Adult; Dihydralazine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Middle Aged; Propranolol; Time Factors | 1978 |
Leukocyte intracellular cations in hypertension: Effect of antihypertensive drugs.
Topics: Adult; Antihypertensive Agents; Electrolytes; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Intracellular Fluid; Leukocytes; Magnesium; Male; Methyldopa; Middle Aged; Potassium; Reserpine; Sodium | 1978 |
Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta.
Topics: Animals; Aortic Coarctation; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol, Dietary; Coronary Disease; Disease Models, Animal; Haplorhini; Hydralazine; Hydrochlorothiazide; Hyperlipidemias; Hypertension; Intracranial Arteriosclerosis; Lipids; Macaca fascicularis; Male; Renin; Reserpine | 1976 |
Elevated blood pressure in the young adult.
Topics: Adult; Age Factors; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Patient Care Planning; Reserpine; Tranquilizing Agents | 1977 |
The effect of norepinephrine on aortic 42K turnover during deoxycorticosterone acetate hypertension and antihypertensive therapy in the rat.
Topics: Animals; Antihypertensive Agents; Aorta; Arteries; Desoxycorticosterone; Dose-Response Relationship, Drug; Hydralazine; Hydrochlorothiazide; Hydroxydopamines; Hypertension; In Vitro Techniques; Male; Norepinephrine; Organ Size; Potassium; Potassium Radioisotopes; Rats; Reserpine | 1977 |
Polypharmacologic drug abuse: presentation and discussion of a case.
Topics: Adult; Child; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Male; Meperidine; Middle Aged; Social Environment; Substance-Related Disorders | 1977 |
Office management of hypertension.
Topics: Antihypertensive Agents; Diuretics; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Physical Examination; Physicians, Family; Potassium; Propranolol; Spironolactone; Triamterene | 1976 |
Treatment of accelerated hypertension and end stage renal failure by bilateral nephrectomy and renal transplantation.
Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Child; Creatinine; Female; Graft Rejection; Guanethidine; Hepatitis; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Kidney; Kidney Transplantation; Male; Methyldopa; Middle Aged; Myocardial Infarction; Nephrectomy; Perfusion; Sepsis; Transplantation, Homologous | 1975 |
Detection and treatment of hypertension at the work site.
Topics: Aged; Allied Health Personnel; Costs and Cost Analysis; Delivery of Health Care; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Labor Unions; Male; Mass Screening; Methyldopa; Middle Aged; New York City; Nurses; Occupational Medicine; Patient Compliance | 1975 |
Evaluation of antihypertensive agents in the stress-induced hypertensive rat.
Topics: Animals; Antihypertensive Agents; Chlorisondamine; Disease Models, Animal; Drug Evaluation, Preclinical; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Phentolamine; Propranolol; Rats; Sotalol; Stress, Physiological | 1975 |
How far should blood pressure be lowered in treating hypertension.
Topics: Blood Pressure; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1975 |
Editorial: Hypertension is worth treating.
Topics: Blood Pressure; Cardiovascular Diseases; Follow-Up Studies; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1975 |
Influence of anti-hypertensive drug treatment on vascular reactivity in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Hydralazine; Hydrochlorothiazide; Hypertension; Mesenteric Arteries; Norepinephrine; Rats; Serotonin | 1975 |
[Treatment of hypertension with propranolol in combination with other antihypertensive agents].
Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Propranolol; Vasodilator Agents | 1975 |
Letter: Impotence during antihypertensive treatment.
Topics: Adult; Erectile Dysfunction; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male | 1976 |
Abnormal electrocardiograms and cardiovascular risk: role of silent myocardial ischemia. Evidence from MRFIT.
Topics: Adult; Antihypertensive Agents; Chlorthalidone; Cholesterol, Dietary; Coronary Disease; Electrocardiography; Humans; Hydralazine; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Missouri; Myocardial Ischemia; Reserpine; Risk Factors; Smoking; Smoking Cessation; Smoking Prevention | 1992 |
Antihypertensive therapy in a model combining spontaneous hypertension with diabetes.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Drug Combinations; Glomerular Filtration Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Indoles; Male; Perindopril; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Reserpine | 1992 |
Effect of antihypertensive treatment on focal cerebral infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cerebral Arteries; Cerebral Infarction; Cilazapril; Hydralazine; Hydrochlorothiazide; Hypertension; Image Processing, Computer-Assisted; Ligation; Male; Pyridazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
[Reserpine and reserpine-containing preparations in hypertension?].
Topics: Diuretics; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Propranolol; Reserpine | 1992 |
[Effects of adelphan-esidrex on hemodynamic indexes at rest and character of their changes during exercise tests].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Exercise Test; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine; Rest | 1991 |
[Interactions of Western antihypertensive drugs and Chinese drugs].
Topics: Antihypertensive Agents; Drug Compounding; Drug Interactions; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Hydralazine; Hydrochlorothiazide | 1990 |
Antihypertensive treatment for the management of premature ventricular complexes. Pilot study.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Infusions, Intravenous; Male; Metaraminol; Methyldopa; Middle Aged; Nitroprusside | 1988 |
Role of lowering arterial pressure on maximal coronary flow with and without regression of cardiac hypertrophy.
Topics: Animals; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Coronary Circulation; Heart; Hydralazine; Hydrochlorothiazide; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Systole; Time Factors | 1989 |
Renal vascular effects of antihypertensive therapy in uninephrectomized SHR.
Topics: Animals; Antihypertensive Agents; Captopril; Enalapril; Hydralazine; Hydrochlorothiazide; Hypertension, Renovascular; Kidney; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Renal Circulation; Reserpine | 1989 |
Effects of antihypertensive drugs on glomerular morphology.
Topics: Animals; Antihypertensive Agents; Enalapril; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Hydralazine; Hydrochlorothiazide; Hypertrophy; Kidney Glomerulus; Male; Rats; Renal Circulation; Reserpine | 1989 |
Short and long term effects of antihypertensive therapy in the diabetic rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetic Nephropathies; Drug Administration Schedule; Drug Therapy, Combination; Glomerular Filtration Rate; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Reserpine; Time Factors | 1989 |
[Spectrophotometric analysis of the multicomponent system: dihydralazine sulfate, hydrochlorothiazide and reserpine].
Topics: Dihydralazine; Hydralazine; Hydrochlorothiazide; Reserpine; Spectrophotometry, Ultraviolet | 1989 |
[Optimization of hypotensive therapy in hospitals].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Cerebrovascular Circulation; Clonidine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Neuropsychological Tests; Reserpine | 1985 |
Hydralazine, hydrochlorothiazide and ampicillin associated with retroperitoneal fibrosis: case report.
Topics: Adult; Ampicillin; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Retroperitoneal Fibrosis; Sinusitis; Time Factors | 1989 |
Therapeutic implications of hypertension-induced glomerular injury. Comparison of enalapril and a combination of hydralazine, reserpine, and hydrochlorothiazide in an experimental model.
Topics: Animals; Enalapril; Glomerular Filtration Rate; Glomerular Mesangium; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Reserpine | 1985 |
Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Glomerular Filtration Rate; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Male; Microcirculation; Natriuresis; Proteinuria; Rats; Renin; Renin-Angiotensin System; Reserpine | 1986 |
Elevated blood pressure during pregnancy.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Nitroprusside; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Rest | 1986 |
[Combined antihypertensive pharmacotherapy].
Topics: Adult; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Reserpine; Time Factors | 1988 |
Effect of antihypertensive therapy on a vascular change in genetically hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Hydralazine; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1987 |
Correlation between mechanistic biotransformation and biochemical toxicology of some antihypertensive drugs.
Topics: Acetylation; Antihypertensive Agents; Biotransformation; Free Radicals; Glucose; Hydralazine; Hydrochlorothiazide; Lipid Peroxidation; Propranolol; Triamterene | 1986 |
Differential structural responses of small resistance vessels to antihypertensive therapy.
Topics: Animals; Antihypertensive Agents; Blood Vessels; Captopril; Hindlimb; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Vascular Resistance | 1987 |
[Efficacy of a graded plan for long-term prevention using antihypertensive drugs. Work Group for the Cooperative Study for the Testing of New Preparations for the Prevention of Arterial Hypertension (CSPPAH)].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Systole | 1987 |
Vascular reactivity in the spontaneously hypertensive stroke-prone rat. Effect of antihypertensive treatment.
Topics: Animals; Blood Pressure; Calcium; Cerebrovascular Disorders; Female; Femoral Artery; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1987 |
Glomerular hypertension and injury in desoxycorticosterone-salt rats on antihypertensive therapy.
Topics: Animals; Blood Pressure; Capillaries; Desoxycorticosterone; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Reserpine; Sodium Chloride | 1987 |
Nephrotoxic serum nephritis with hypertension: amelioration by antihypertensive therapy.
Topics: Animals; Antihypertensive Agents; Dietary Proteins; Glomerular Filtration Rate; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Kidney; Kidney Glomerulus; Male; Nephritis; Rats; Rats, Inbred Strains; Renal Circulation; Reserpine | 1985 |
[Arterial hypertension in chronic bronchial obstruction and various problems of its treatment].
Topics: Adult; Asthma; Bronchitis; Chronic Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Monoamine Oxidase; Propanolamines; Serotonin | 1985 |
Serial measurements of systolic time intervals during treatment with hydrochlorothiazide alone and combined with other antihypertensive agents.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Electrocardiography; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Myocardial Contraction; Oxprenolol; Prazosin; Propranolol; Systole; Time Factors | 1985 |
[Hypotensive effect and tolerability of a short course of treatment with prazosin (pratsiol) and hydralazine (apressin) in a cooperative study of new drugs for the prevention of arterial hypertension].
Topics: Adult; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Quinazolines; Time Factors | 1985 |
Function of the isolated spontaneously hypertensive rat kidney after blood pressure reduction.
Topics: Animals; Blood Pressure; Diazoxide; Drug Evaluation, Preclinical; Hydralazine; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Kidney; Male; Placebos; Rats; Rats, Inbred SHR; Reserpine | 1985 |
Results of treatment of hypertension.
Topics: Acute Kidney Injury; Antihypertensive Agents; Cardiovascular Diseases; Coronary Disease; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Myocardial Infarction; Placebos; Prognosis; Reserpine; Sex Factors | 1971 |
Arterial hypertension--northwest Florida public health survey. II. Diagnosis and treatment.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Chlorothiazide; Diuretics; Drug Therapy, Combination; Female; Furosemide; Hematuria; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Diseases; Male; Middle Aged; Proteinuria; Reserpine; Time Factors | 1974 |
Combined therapy with vasodilator drugs and beta-adrenergic blockade in hypertension. A comparative study of minoxidil and hydralazine.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Body Weight; Cardiac Output; Female; Furosemide; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Imines; Kidney; Male; Middle Aged; Piperidines; Propranolol; Pyrimidines; Renin; Sodium | 1972 |
Beta-blocking therapy: Propranolol.
Topics: Cardiac Output; Central Nervous System; Drug Therapy, Combination; Furosemide; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Minoxidil; Propranolol; Renin | 1974 |
Office management of hypertension.
Topics: Adult; Aged; Ambulatory Care; Drug Therapy, Combination; Female; Follow-Up Studies; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Phytotherapy; Plants, Medicinal; Private Practice; Rauwolfia; Time Factors | 1974 |
Practical office management of chronic hypertension.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Physician-Patient Relations; Private Practice; Propranolol; Reserpine; Thiazines | 1974 |
Malignant hypertension in children; a patient treated with bilateral nephrectomy.
Topics: Blood Pressure; Child; Creatinine; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Kidney Failure, Chronic; Kidney Transplantation; Methyldopa; Nephrectomy; Propranolol; Retinal Detachment; Transplantation, Homologous | 1974 |
Vascular reactivity in hypertensive rats after treatment with anti-hypertensive agents.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Hydralazine; Hydrochlorothiazide; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Reserpine; Serotonin; Vasoconstrictor Agents | 1974 |
[Antihypertensive agents].
Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlorisondamine; Chlorthalidone; Diuretics; Furosemide; Guanethidine; Guanidines; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Mecamylamine; Methyldopa; Pain; Parotid Gland; Pempidine; Phentolamine; Structure-Activity Relationship; Sulfonamides | 1972 |
Minoxidil in severe hypertension with renal failure. Effect of its addition to conventional antihypertensive drugs.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Evaluation Studies as Topic; Female; Follow-Up Studies; Furosemide; Guanethidine; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertrichosis; Hypotension, Orthostatic; Kidney Failure, Chronic; Male; Methyldopa; Middle Aged; Minoxidil; Nausea; Piperidines; Pyrimidines | 1973 |
Problems in therapy for the hypertensive patient.
Topics: Antihypertensive Agents; Blood Pressure; Carotid Sinus; Diuretics; Electric Stimulation; Ethacrynic Acid; Female; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypertension, Renal; Hypotension, Orthostatic; Male; Methyldopa; Nephrectomy; Phytotherapy; Plants, Medicinal; Posture; Rauwolfia; Spironolactone; Uremia | 1973 |
How to treat arterial hypertension.
Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Cooperative Behavior; Diazoxide; Diuretics; Ethacrynic Acid; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Methyldopa; Physician-Patient Relations; Reserpine; Spironolactone; Sulfonamides; Triamterene | 1973 |
[Therapy of EPH gestosis].
Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Magnesium Sulfate; Mannitol; Phenobarbital; Phytotherapy; Plants, Medicinal; Pre-Eclampsia; Pregnancy; Proteinuria; Rauwolfia | 1973 |
[Evaluation of antihypertensive therapy with Adelphan-Esidrex by clinical and psychometric parameters].
Topics: Adult; Aged; Blood Pressure; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pulse; Reserpine; Sleep Wake Disorders | 1973 |
Drug failure in reducing pressor effect of isometric handgrip stress test in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Electrocardiography; Female; Guanethidine; Hand; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Muscle Contraction; Pilot Projects; Reserpine; Stress, Physiological | 1973 |
[Electrolyte metabolism in patients with hypertensive disease treated with hyparez].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Potassium Chloride; Reserpine; Sodium | 1973 |
Fluorescein circulation time and the treatment of hypertension in the aged.
Topics: Adult; Age Factors; Aged; Blood Circulation Time; Blood Pressure; Carbamates; Ethacrynic Acid; Female; Fluoresceins; Furosemide; Glomerular Filtration Rate; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Failure, Chronic; Male; Methyldopa; Middle Aged; Potassium; Reserpine; Spironolactone | 1973 |
Hypertension: challenge in preventive medicine.
Topics: Aged; Aneurysm; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Drug Therapy, Combination; Follow-Up Studies; Heart Failure; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Reserpine | 1973 |
Treatment of malignant hypertension with sodium nitroprusside.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Chemical Phenomena; Chemistry; Diazoxide; Drug Resistance; Female; Ferricyanides; Furosemide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Injections, Intramuscular; Injections, Intravenous; Male; Methyldopa; Middle Aged; Nitric Oxide; Reserpine; Thiocyanates; Time Factors | 1974 |
Treatment of hypertension with Ser-Ap-Es.
Topics: Adult; Aged; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1967 |
Simultaneous automated determination of hydralazine hydrochloride, hydrochlorothiazide, and reserpine in single tablet formulations.
Topics: Autoanalysis; Colorimetry; Drug Combinations; Fluorometry; Hydralazine; Hydrochlorothiazide; Reserpine; Tablets | 1972 |
A versatile automated system for the spectrophotometric analysis of single tablets.
Topics: Autoanalysis; Hydralazine; Hydrochlorothiazide; Solutions; Spectrophotometry; Tablets; Tripelennamine | 1968 |
[Maximum consumption of oxygen and work capacity in patients with essential arterial hypertension after treatment].
Topics: Adolescent; Adult; Disability Evaluation; Exercise Test; Female; Heart; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxygen Consumption; Reserpine | 1969 |
[Influence of a combinated adelphan-esidrix and clonidin therapy on blood pressure and renal function in renal hypertension].
Topics: Adult; Aniline Compounds; Blood Pressure Determination; Blood Urea Nitrogen; Drug Synergism; Female; Glomerular Filtration Rate; Humans; Hydralazine; Hydrazines; Hydrochlorothiazide; Hypertension, Renal; Imidazoles; Male; Metabolic Clearance Rate; Middle Aged; Reserpine; Time Factors | 1971 |
[Results of combined therapy (Adelphan-Esidrix and Ismelin) in severe hypertension].
Topics: Antihypertensive Agents; Drug Synergism; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Reserpine | 1967 |
[Results of hypotensive treatment in a hospital environment].
Topics: Adult; Aged; Arteriosclerosis; Carbamates; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Middle Aged | 1968 |
Management of severe hypertension with a combination of Adelphane-Esidrex and guanethidine sulphate (Ismelin).
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1968 |
Fourteen-year survival in a case of malignant hypertension under hypotensive drug therapy.
Topics: Adult; Antihypertensive Agents; Chlorothiazide; Guanethidine; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Male; Mecamylamine; Methyldopa; Pempidine; Pentolinium Tartrate; Phytotherapy; Plants, Medicinal; Rauwolfia | 1968 |
[Objectives and methods in therapy of essential arterial hypertension].
Topics: Antihypertensive Agents; Chlorthalidone; Diuretics; Ethacrynic Acid; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Potassium; Reserpine; Triamterene | 1968 |
[Considerations on ambulatory therapy in a group of hypertensive patients].
Topics: Adult; Aged; Ambulatory Care; Carbamates; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Methyldopa; Middle Aged; Reserpine | 1969 |
Essential hypertension--effective therapy in private practice.
Topics: Adult; Aged; Antihypertensive Agents; Drug Synergism; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1969 |
Hypotensive drug therapy in the management of hypertension.
Topics: Antihypertensive Agents; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Pargyline; Reserpine; Spironolactone | 1969 |
[Clinical trials of a new antihypertensive drug association in aged subjects. Behavior of the electrolyte pattern].
Topics: Aged; Carbamates; Electrolytes; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Potassium Chloride | 1966 |
[The treatment of hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Child; Child, Preschool; Coronary Disease; Female; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Infant; Infant, Newborn; Kidney Diseases; Male; Middle Aged; Reserpine | 1966 |
The nephrotic syndrome: current concepts in diagnosis and therapy advantages of alternate day steroid regimen.
Topics: Alkylating Agents; Anti-Bacterial Agents; Child; Child, Preschool; Ethacrynic Acid; Humans; Hydralazine; Hydrochlorothiazide; Mechlorethamine; Mercaptopurine; Nephrotic Syndrome; Prednisone; Reserpine; Thioguanine | 1967 |
[Contribution to anti-hypertensive therapy with a drug combination].
Topics: Aged; Carbamates; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium Chloride | 1967 |
Antihypertensive effects of drugs measured in unanesthetized rats with established adrenal regeneration hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorisondamine; Diazoxide; Female; Guanethidine; Hydralazine; Hydrochlorothiazide; Methyldopa; Plants, Medicinal; Plants, Toxic; Rats; Reserpine; Veratrum | 1967 |
[Antihypertensive therapy in pregnancy].
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular | 1982 |
Inhibitors of angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Blood Pressure; Bradykinin; Captopril; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Protease Inhibitors; Rabbits; Rats; Snake Venoms; Structure-Activity Relationship | 1980 |
Efficacy of an oral angiotensin-converting enzyme inhibitor (captopril) in severe hypertension.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol | 1981 |
Slow-release metoprolol, hydrochlorothiazide and hydralazine in stepwise treatment of essential hypertension.
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Follow-Up Studies; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged | 1984 |
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Clonidine; Drug Combinations; Drug Evaluation; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Intracranial Arteriosclerosis; Methyldopa; Middle Aged; Reserpine; Time Factors | 1984 |
[Use of adelphan-esidrex with hypertension patients].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Electrocardiography; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine; Tablets; Time Factors | 1984 |
[Hemodynamic indicators, phase structure of the systole of the left and right heart ventricles and the state of pulmonary circulation and microcirculation in patients with hypertension treated with adelphane-esindex].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Heart Ventricles; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Microcirculation; Middle Aged; Myocardial Contraction; Pulmonary Circulation; Reserpine; Systole | 1983 |
[Changes in the hemodynamic indices of hypertension patients].
Topics: Adult; Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Drug Evaluation; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1983 |
Some wrong-way chemical changes during antihypertensive treatment: comparison of indapamide and related agents.
Topics: Adult; Antihypertensive Agents; Chemical Phenomena; Chemistry; Chlorthalidone; Diuretics; Humans; Hydralazine; Hydrochlorothiazide; Hypercholesterolemia; Hyperglycemia; Hypokalemia; Indapamide; Middle Aged; Myocardial Infarction; Uric Acid | 1983 |
Captopril in severe treatment-resistant hypertension.
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Female; Furosemide; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Myocardial Infarction; Proline; Propranolol; Renin | 1980 |
[Captopril in treatment-resistant hypertension (author's transl)].
Topics: Adult; Captopril; Diastole; Drug Combinations; Female; Furosemide; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Proline; Propranolol; Pulse; Systole; Time Factors | 1980 |
[Changes In myocardial contractile function and microcirculation in hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Conjunctiva; Drug Combinations; Drug Evaluation; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Microcirculation; Middle Aged; Myocardial Contraction; Reserpine | 1982 |
Effects of antihypertensive agents on blood velocity: implications for atherogenesis.
Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Blood Flow Velocity; Blood Pressure; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nadolol; Placebos; Propanolamines; Propranolol; Ultrasonography | 1982 |
[Adelphan-esidrex in the treatment of hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1980 |
[Combined action of oxprenolol, hydrochlorothiazide and hydralazine in rats with metacorticoid induced hypertension].
Topics: Animals; Desoxycorticosterone; Drug Evaluation; Drug Therapy, Combination; Hydralazine; Hydrochlorothiazide; Hypertension; Oxprenolol; Rats | 1980 |
[Treatment of hypertension with clofelin and adelfan-esidrex].
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Dihydralazine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Reserpine | 1980 |
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Caffeine; Calcium; Calcium Channels; Cell Membrane; Disease Models, Animal; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcoplasmic Reticulum | 1993 |
Influence of differing classes of antihypertensive agents on mesangial kinetics following partial renal ablation in rats.
Topics: Albuminuria; Animals; Antihypertensive Agents; Biological Transport, Active; Enalapril; Glomerular Mesangium; Hydralazine; Hydrochlorothiazide; Hypertrophy; Kidney Glomerulus; Kinetics; Male; Nephrectomy; Rats; Rats, Wistar; Reserpine; Serum Albumin, Bovine; Tissue Distribution | 1994 |
Effects of long-term antihypertensive treatment and aging on renal function and albumin excretion in primary hypertension.
Topics: Aging; Albuminuria; Case-Control Studies; Drug Therapy, Combination; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Male; Metoprolol; Middle Aged; Renal Circulation | 1993 |
Effects of antihypertensive drugs on the progress of renal failure in hyperlipidemic Imai rats.
Topics: Animals; Antihypertensive Agents; Cholesterol; Drug Therapy, Combination; Enalapril; Hydralazine; Hydrochlorothiazide; Hyperlipidemias; Hypertension; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; Proteinuria; Rats; Reserpine; Time Factors | 1993 |
The effects of perindopril and triple therapy in a normotensive model of diabetic nephropathy.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Glomerular Filtration Rate; Glomerular Mesangium; Hydralazine; Hydrochlorothiazide; Indoles; Kidney Glomerulus; Male; Perindopril; Rats; Rats, Sprague-Dawley; Reserpine | 1993 |
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Hydralazine; Hydrochlorothiazide; Hypertension; Linear Models; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1995 |
Organ specificity of antihypertensive therapy on ocular albumin vascular clearance and albuminuria in the hypertensive diabetic rat.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dihydropyridines; Drug Therapy, Combination; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Indoles; Kidney; Male; Organ Specificity; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reserpine; Retina; Serum Albumin | 1996 |
Glomerulosclerosis in kidney transplants: pathophysiologic mechanisms.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Capillaries; Cilazapril; Graft Rejection; Graft Survival; Hydralazine; Hydrochlorothiazide; Imidazoles; Kidney Glomerulus; Kidney Transplantation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reserpine; Tetrazoles; Transplantation, Homologous | 1996 |
Effects of treatment with angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor antagonist (AIIRA) on renal function and glomerular injury in subtotal nephrectomized rats.
Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Creatinine; Enalapril; Glomerulonephritis; Hydralazine; Hydrochlorothiazide; Imidazoles; Kidney; Kidney Glomerulus; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Reserpine; Tetrazoles | 1997 |
Effects of benidipine hydrochloride on antioxidant enzyme activity in stroke-prone spontaneous hypertensive rats (SHR-SP).
Topics: Animals; Antioxidants; Blood Pressure; Calcium Channel Blockers; Catalase; Cerebrovascular Disorders; Creatine; Dihydropyridines; Drug Therapy, Combination; Glutathione Peroxidase; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Male; Organ Size; Oxidoreductases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reserpine; Superoxide Dismutase | 1997 |
Effects of antihypertensive drugs or glycemic control on antioxidant enzyme activities in spontaneously hypertensive rats with diabetes.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Captopril; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Glutathione Peroxidase; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reserpine; Superoxide Dismutase | 1997 |
Perindopril ameliorates glomerular and renal tubulointerstitial injury in the SHR/N-corpulent rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Hydralazine; Hydrochlorothiazide; Hypertension; Indoles; Kidney Glomerulus; Kidney Tubules; Male; Obesity; Perindopril; Rats; Rats, Inbred SHR; Reserpine; Time Factors | 1997 |
Effects of antihypertensive drugs on antioxidant enzyme activities and renal function in stroke-prone spontaneously hypertensive rats.
Topics: Acetylglucosaminidase; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Catalase; Drug Therapy, Combination; Glutathione Peroxidase; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Function Tests; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; Reserpine; Superoxide Dismutase | 1997 |
Regulation of glomerular TGF-beta expression in the contralateral kidney of two-kidney, one-clip hypertensive rats.
Topics: Animals; Antihypertensive Agents; Drug Combinations; Hydralazine; Hydrochlorothiazide; Hypertension, Renovascular; Kidney; Kidney Glomerulus; Losartan; Male; Rats; Rats, Wistar; Reserpine; RNA, Messenger; Sclerosis; Time Factors; Transforming Growth Factor beta | 1998 |
Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Cell Nucleus; Diastole; DNA; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Indoles; Losartan; Lymphocytes; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Perindopril; Rats; Rats, Inbred SHR; Systole; Telemetry; Time Factors | 1999 |
Renoprotection by nitric oxide donor and lisinopril in the remnant kidney model.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Creatinine; Disease Progression; Eating; Endothelin-1; Hydralazine; Hydrochlorothiazide; Kidney; Lisinopril; Male; Molsidomine; Nephrectomy; Nitric Oxide; Nitric Oxide Donors; Nitrous Oxide; Rats; Rats, Sprague-Dawley; Reserpine | 1999 |
Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta, Thoracic; Aortic Diseases; Cardiomegaly; Cell Cycle; DNA; Drug Therapy, Combination; Female; Flow Cytometry; Follow-Up Studies; Heart Ventricles; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertrophy; Indoles; Male; Muscle, Smooth, Vascular; Perindopril; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Transgenes | 1999 |
Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Diuresis; Glomerular Filtration Rate; Humans; Hydralazine; Hydrochlorothiazide; Ki-67 Antigen; Kidney; Male; Myocardium; Natriuresis; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; Reserpine; Sodium; Transgenes | 2000 |
Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Diuretics; Drug Therapy, Combination; Enalapril; Glomerular Filtration Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertrophy; Kidney; Male; Proteinuria; Rats; Rats, Inbred SHR; Reserpine; Sodium Chloride Symporter Inhibitors | 1999 |
Angiotensin-converting enzyme inhibitor prevents age-related endothelial dysfunction.
Topics: Acetylcholine; Administration, Oral; Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biological Factors; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Heart Rate; Hydralazine; Hydrochlorothiazide; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Inbred WKY; Vasodilation | 2000 |
AT1 receptor antagonist combats oxidative stress and restores nitric oxide signaling in the SHR.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Combinations; Feedback; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Glomerulus; Kidney Tubules; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Reserpine; Signal Transduction; Tetrazoles; Transforming Growth Factors | 2001 |
The influence of chronic antihypertensive treatment on the central pressor response in SHR.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Brain; Enalapril; Epinephrine; Heart Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Injections, Intraventricular; Losartan; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Saline Solution, Hypertonic; Tetrazoles | 2001 |
Persistent lowering of arterial pressure after continuous and intermittent therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Enalapril; Heart Rate; Heart Ventricles; Hydralazine; Hydrochlorothiazide; Hypertension; Losartan; Male; Nifedipine; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Vasodilator Agents | 2003 |
[On the treatment of pre-eclampsia with Esidrex and Adelphan-Esidrex].
Topics: Chlorothiazide; Drug Combinations; Female; Hydralazine; Hydrazines; Hydrochlorothiazide; Pre-Eclampsia; Pregnancy; Reserpine | 1961 |
[Adelphan esidrex in medical practice].
Topics: Chlorothiazide; Drug Combinations; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1960 |
[Reserpine-hydrazinophthalazine-hydrochlorothiazide combination in the treatment of hypertension].
Topics: Chlorothiazide; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1962 |
[Comparative study of the effectiveness of drug therapy in hypertensive disease].
Topics: Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine; Vasodilator Agents | 1963 |
A broad ranged antihypertensive combination (Ser-Ap-Es).
Topics: Antihypertensive Agents; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1963 |
[Treatment of hypertension with 2 new preparations].
Topics: Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1962 |
Vascular lesions in experimental renal hypertension, with special reference to effect of hypotensive treatment.
Topics: Arteries; Cerebral Hemorrhage; Coronary Vessels; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Reserpine | 1963 |
Dangers in the use of some potent drugs.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antihypertensive Agents; Antipsychotic Agents; Chloramphenicol; Chlorothiazide; Diuretics; Enterocolitis; Female; Gonadal Steroid Hormones; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Male; Meprobamate; Penicillins; Phenothiazines; Reserpine; Sodium Chloride Symporter Inhibitors; Staphylococcal Infections; Steroids | 1962 |
[CURRENT THERAPY OF HYPERTENSION].
Topics: Antihypertensive Agents; Benzothiadiazines; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1963 |
PRE-ECLAMPTIC TOXAEMIA OF PREGNANCY AND THE USE OF ANTI-HYPERTENSIVE DRUGS.
Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hydrochlorothiazide; Pre-Eclampsia; Pregnancy; Reserpine | 1963 |
[CLINICAL STUDY OF A NEW COMPLEX HYPOTENSIVE DRUG COMBINATION].
Topics: Antihypertensive Agents; Arteriosclerosis; Carbamates; Cerebrovascular Disorders; Coronary Disease; Diabetic Angiopathies; Drug Combinations; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Liver Cirrhosis; Potassium | 1963 |
[CLINICAL RESEARCH WITH A COMPOUND HYPOTENSIVE PREPARATION (MEBUTAMATE + 1-4 DIHYDRAZINOPHTHALAZINE + DIHYDROCHLOROTHIAZIDE + POTASSIUM)].
Topics: Antihypertensive Agents; Arteriosclerosis; Carbamates; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Kidney; Nephritis; Nephrosclerosis; Potassium | 1963 |
THE HYPERGLYCEMIC EFFECT OF HYPOTENSIVE DRUGS.
Topics: Antihypertensive Agents; Benzothiadiazines; Black People; Blood Glucose; Diazoxide; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hyperglycemia; Hypertension; Infusions, Parenteral; Maryland; Toxicology | 1964 |
GUANETHIDINE IN COMBINATION WITH HYDRALAZINE AND WITH HYDROCHLOROTHIAZIDE IN HYPERTENSION.
Topics: Blood Pressure Determination; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; Toxicology | 1964 |
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine; Hemiplegia; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Methyldopa; Neurologic Manifestations; Reserpine; Toxicology | 1964 |
[CONSIDERATIONS ON THE RENAL SIDE-EFFECTS DURING TREATMENT OF ARTERIAL HYPERTENSION].
Topics: Bretylium Compounds; Chlorothiazide; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Diseases; Reserpine; Toxicology | 1964 |
COMPARISON OF ALPHA-METHYLDOPA WITH STANDARD ANTIHYPERTENSIVE THERAPY IN MAN.
Topics: Antihypertensive Agents; Blood Pressure Determination; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Methyldopa; Reserpine; Toxicology; Veratrum | 1964 |
LONG TERM THERAPY WITH GUANETHIDINE AND ASSOCIATED ANTIHYPERTENSIVE DRUGS.
Topics: Antihypertensive Agents; Guanethidine; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1964 |
COMBINATION DRUG THERAPY OF HYPERTENSION.
Topics: Drug Therapy; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine; Toxicology | 1964 |
USE OF SER-AP-ES FOR HYPERTENSION.
Topics: Biomedical Research; Drug Therapy; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Reserpine | 1964 |
[TREATMENT OF PREGNANCY TOXICOSIS WITH ADELPHIN-ESIDREX-K].
Topics: Drug Therapy; Female; Hydralazine; Hydrochlorothiazide; Pre-Eclampsia; Pregnancy; Reserpine | 1964 |
[CLINICAL EVALUATION OF A PHARMACOLOGIC ASSOCIATION WITH HYPOTENSIVE ACTION].
Topics: Antihypertensive Agents; Biomedical Research; Carbamates; Drug Therapy; Electric Impedance; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Plethysmography; Plethysmography, Impedance; Potassium; Potassium Chloride | 1964 |
LUPUS GLOMERULONEPHRITIS. THE EFFECT OF LARGE DOSES OF CORTICOSTEROIDS ON RENAL FUNCTION AND RENAL LESIONS IN TWO CHILDREN.
Topics: Adolescent; Adrenal Cortex Hormones; Cortisone; Drug Therapy; Glomerulonephritis; Guanethidine; Hydralazine; Hydrochlorothiazide; Kidney Function Tests; Lupus Erythematosus, Systemic; Lupus Nephritis; Methantheline; Pathology; Prednisone; Propantheline; Quaternary Ammonium Compounds; Reserpine; Spironolactone; Triamcinolone | 1965 |
Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Enalapril; Glomerulosclerosis, Focal Segmental; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Male; Monitoring, Physiologic; Nephrectomy; Rats; Rats, Sprague-Dawley; Reserpine; Telemetry | 2004 |
Tight blood pressure control decreases apoptosis during renal damage.
Topics: Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Cell Division; Drug Therapy, Combination; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Immunohistochemistry; Losartan; Male; Proteinuria; Quinapril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reserpine; Tetrahydroisoquinolines | 2004 |
Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Therapy, Combination; Homeostasis; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reserpine; Tetrazoles; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Blockade of angiotensin II provides additional benefits in hypertension- and ageing-related cardiac and vascular dysfunctions beyond its blood pressure-lowering effects.
Topics: Aging; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Coronary Vessels; Hydralazine; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride Symporter Inhibitors; Vasodilation; Vasodilator Agents | 2005 |
Differential expression of components of the cardiomyocyte adrenomedullin/intermedin receptor system following blood pressure reduction in nitric oxide-deficient hypertension.
Topics: Adrenomedullin; Animals; Body Weight; Hydralazine; Hydrochlorothiazide; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Myocytes, Cardiac; Myosin Heavy Chains; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Peptides; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Protein 2; Receptor Activity-Modifying Protein 3; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; RNA, Messenger; Systole | 2006 |
Impact of antihypertensive treatments on erectile responses in aging spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Enalapril; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Transplantation; Losartan; Male; Nifedipine; Penile Erection; Random Allocation; Rats; Rats, Inbred SHR; Testosterone | 2006 |
Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Drug Therapy, Combination; Erythropoietin; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Losartan; Nephrectomy; Rats; Rats, Wistar; Recombinant Proteins; Renin-Angiotensin System; Reserpine; Time Factors; Uremia | 2006 |
Prevention of hypertension abrogates early inflammatory events in the retina of diabetic hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Diabetic Retinopathy; Drug Combinations; Eye Proteins; Hydralazine; Hydrochlorothiazide; Hypertension; Immunohistochemistry; Intercellular Adhesion Molecule-1; Losartan; Male; Microglia; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reserpine; Retina; Transcription Factor RelA | 2007 |
Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Enalapril; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney Cortex; Kidney Medulla; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Reserpine; Sodium; Sodium Chloride Symporters; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Potassium-Chloride Symporters | 2007 |
Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Desoxycorticosterone; Heart Ventricles; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Renal; Kidney; Losartan; Mice; Mineralocorticoid Receptor Antagonists; Nephrosclerosis; p38 Mitogen-Activated Protein Kinases; Rats; Renin; Reserpine; RNA, Messenger; Spironolactone | 2008 |
Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Disease Progression; Diuretics; Dose-Response Relationship, Drug; Glomerulonephritis; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Nephrosclerosis; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reserpine; Spironolactone | 2008 |
Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Brain; Electron Spin Resonance Spectroscopy; Heart Rate; Hydralazine; Hydrochlorothiazide; Hypertension; Imidazoles; Male; NADPH Oxidases; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Tetrazoles | 2009 |
Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Cyclic GMP; GTP Cyclohydrolase; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reserpine; Signal Transduction | 2011 |
Tetrahydrobiopterin and hypertension: more than an emigrating story.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Reserpine; Signal Transduction | 2011 |
Role of blood pressure and the renin-angiotensin system in development of diabetic nephropathy (DN) in eNOS-/- db/db mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hydralazine; Hydrochlorothiazide; Mice; Mice, Knockout; Nitric Oxide Synthase Type III; Renin-Angiotensin System; Reserpine | 2012 |
Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydralazine; Hydrochlorothiazide; Imidazoles; Juxtaglomerular Apparatus; Male; Membrane Proteins; Podocytes; Rats; Rats, Inbred OLETF; Reserpine; Tetrazoles | 2012 |
Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Blood Pressure; Cell Dedifferentiation; Cell Line; Chemokine CCL20; Cytoprotection; Disease Models, Animal; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Inflammation; Isoantibodies; Macrophages; Male; Mice; Nephrectomy; Podocytes; Proteinuria; Rats; Rats, Wistar; Receptors, CCR6; Receptors, Platelet-Derived Growth Factor; RNA Interference; RNA, Messenger; Telmisartan; Time Factors; Transfection | 2013 |
Critical blood pressure threshold dependence of hypertensive injury and repair in a malignant nephrosclerosis model.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Enalapril; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Nephrosclerosis; Rats; Rats, Inbred SHR; Reference Values; Treatment Outcome | 2014 |
Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
Topics: Animals; Collagen; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Diabetic Nephropathies; Glomerular Basement Membrane; Hydralazine; Hydrochlorothiazide; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice, Knockout; Orchiectomy; Renin-Angiotensin System; Reserpine; Sodium | 2015 |
Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor.
Topics: Animals; Antihypertensive Agents; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebrovascular Circulation; Cerebrum; Compliance; Eplerenone; Hydralazine; Hydrochlorothiazide; Hypertension; Middle Cerebral Artery; Mineralocorticoid Receptor Antagonists; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Mineralocorticoid; Reserpine; Spironolactone; Vascular Remodeling; Vascular Stiffness | 2015 |
Pentosan polysulfate preserves renal microvascular P2X1 receptor reactivity and autoregulatory behavior in DOCA-salt hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Arterioles; Blood Pressure; Chemokine CCL2; Disease Models, Animal; Homeostasis; Hydralazine; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Kidney; Male; Pentosan Sulfuric Polyester; Proteinuria; Rats, Sprague-Dawley; Receptors, Purinergic P2X1; Reserpine; Vasoconstriction | 2016 |