hydralazine has been researched along with hydrazine in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (76.79) | 18.7374 |
| 1990's | 8 (14.29) | 18.2507 |
| 2000's | 4 (7.14) | 29.6817 |
| 2010's | 1 (1.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carpi, C; Dorigotti, L; Rolandi, R | 1 |
| Bertel, O; Bolli, P; Bühler, FR; Kiowski, W; van Brummelen, P | 1 |
| Deguchi, T; Ishii, A; Kubo, K; Tanaka, M | 1 |
| Harland, SJ; Timbrell, JA | 1 |
| Iguchi, S; Matsuyama, K; Noda, A; Noda, H; Otsuji, N; Yen, SH | 1 |
| Dorigotti, L; Parravicini, F; Pifferi, G; Scarpitta, G | 1 |
| Worcel, M | 2 |
| Cieszyński, T | 1 |
| Engelhart, G; Herbolt, B; Jäckh, R; Jung, R; Müller, W | 1 |
| Grönberg, L; Gyllenhaal, O; Vessman, J | 1 |
| Drózdz, M; Kula, B; Wardas, M; Weglarz, L | 1 |
| Drózdz, M; Kucharz, EJ; Olczyk, K | 1 |
| Smits, JF; Struyker-Boudier, HA | 1 |
| Beever, IA; Blair, IA; Brodie, MJ; Clare, RA; Dollery, CT; Mansilla Tinoco, R; Timbrell, JA | 1 |
| Kawai, K; Kitamura, J; Mori, H; Sugie, S | 1 |
| Hovding, G | 1 |
| Akashi, A; Chiba, T; Kasahara, A | 1 |
| Deguchi, T; Ishii, A; Takahira, H | 1 |
| Baldoli, E; Bianchi, G; Capellini, M; Dezulian, V; Sardi, A | 1 |
| Shimizu, H; Toth, B | 1 |
| Bräuniger, H; Moede, R | 1 |
| Freyland, MD; Frotscher, U; Messerschmidt, W; Piehl, W; Wilbrandt, R | 1 |
| Chruściel, M | 1 |
| Reidenberg, MM | 1 |
| Sinha, BK | 1 |
| Hatano, M; Hibiya, K; Ichikawa, M; Nagasawa, M; Ozawa, Y; Saito, S; Tamura, Y; Tomobe, K; Yumikura, S | 1 |
| Lovering, EG; Matsui, F; Robertson, DL | 1 |
| Curran, NM; Lovering, EG; Matsui, F; Robertson, DL; Sears, RW | 1 |
| Chevillard, C; Saiag, B; Worcel, M | 1 |
| Cybulska, I | 1 |
| Vidrio, H | 1 |
| Mathison, BH; Murphy, SE; Shank, RC | 1 |
| Novak, RF; Runge-Morris, M; Wu, N | 1 |
| Engelhart, G; Herbold, B; Jäckh, R; Jung, R; Müller, W | 1 |
| Calleja, JM; Castro, ME; de los Reyes Laguna, M; Fontenla, JA; Gil-Longo, J; Orallo, F; Ravina, E; Teran, C; Verde, I | 1 |
| Feng, Y; Novak, RF; Runge-Morris, M; Zangar, RC | 1 |
| Abe, Y; Chen, QH; Kosaka, H; Tian, RX; Yamamoto, A; Yoneyama, H; Zhang, L; Zhou, MS | 1 |
| Alvarez, E; Fernández, G; Medina, M; Orallo, F; Vidrio, H | 1 |
| MEIER, R; SCHULER, W | 1 |
| LATTANZI, A; PANICHI, S | 1 |
| AVRIL, P; BENYAMINE, R | 1 |
| CALDWELL, JR; REYNOLDS, H | 1 |
| LOYBER, J | 1 |
| ABE, T; OBATA, K; OGASAWARA, S; SUGITA, M; YOKOI, T | 1 |
| CIOBANU, V; VELICAN, D | 1 |
| HOPFGARTNER, A | 1 |
| SCHULERT, AR | 1 |
| MONIER, JC | 1 |
| FROST, J; HJORTH, N | 1 |
| MALTEN, KE | 1 |
| HANDLEY, CA; MOYER, JH | 1 |
| HANDLEY, CA; HUGGINS, RA; MOYER, JH | 1 |
| Ishikawa, N; Kurokawa, K; Miyata, T | 1 |
| Elbaz, M; Escargueil-Blanc, I; Grazide, MH; Marcheix, B; Nègre-Salvayre, A; Salvayre, R; Uchida, K; Vindis, C | 1 |
| Li, H; Luo, H; Luo, W; Yang, W | 1 |
1 review(s) available for hydralazine and hydrazine
| Article | Year |
|---|---|
[Carbonyl stress inhibitor towards new therapeutic interventions in diabetic nephropathy].
Topics: Amides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Diabetes Mellitus; Diabetic Nephropathies; Glycation End Products, Advanced; Guanidines; Humans; Hydralazine; Hydrazines; Imidazoles; Olmesartan Medoxomil; Oxidative Stress; Pyridoxamine; Tetrazoles | 2004 |
1 trial(s) available for hydralazine and hydrazine
| Article | Year |
|---|---|
Antihypertensive efficacy of a new long acting hydralazine like vasodilator, ISF 2469 in combination with a betablocker and a diuretic.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Humans; Hydralazine; Hydrazines; Hypertension; Male; Middle Aged; Prazosin; Pyridazines; Vasodilator Agents | 1979 |
54 other study(ies) available for hydralazine and hydrazine
| Article | Year |
|---|---|
A new antihypertensive compound: 3 hydrazino-6- [(2-hydroxypropyl)methylamino] pyridazine dihydrochloride (ISF 2123).
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Histamine H1 Antagonists; Hydralazine; Hydrazines; Hypertension, Renal; In Vitro Techniques; Injections, Intravenous; Muscle, Smooth; Parasympatholytics; Pyridazines; Rats; Species Specificity | 1976 |
[Inhibition of cyclic AMP phosphodiesterase activity by ecarazine hydrochloride, hydralazine and their metabolites (author's transl)].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Guinea Pigs; Hydralazine; Hydrazines; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Todralazine | 1979 |
Identification and quantitation of hydrazine in the urine of patients treated with hydralazine.
Topics: Acetylation; Biotransformation; Chromatography, Gas; Drug Stability; Humans; Hydralazine; Hydrazines; In Vitro Techniques; Mass Spectrometry; Methods; Phenotype | 1979 |
Identification of hydrazine derived from hydralazine in experimental animals.
Topics: Animals; Chemical Phenomena; Chemistry; Hydralazine; Hydrazines; Male; Rabbits; Rats | 1979 |
[3-Hydrazinepyridazine derivatives. III. Synthesis and anti-hypertensive activity of new 3-(2-acylhydrazine)-pyridazine-6-alkylamino substitutes].
Topics: Animals; Antihypertensive Agents; Hydralazine; Hydrazines; Hypertension; Pyridazines; Rats; Todralazine | 1979 |
Mechanism of action of hydralazine and ISF 2123 on arterial smooth muscle [proceedings].
Topics: Animals; Arteries; Hydralazine; Hydrazines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pyridazines; Rats | 1978 |
Relationship between the direct inhibitory effect of hydralazine and propildazine on arterial smooth muscle contractility and sympathetic innervation.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Hydralazine; Hydrazines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pyridazines; Rats; Sympathetic Nervous System | 1978 |
[Identification of binazine and dihydralazine by new color reactions].
Topics: Color; Dihydralazine; Hydralazine; Hydrazines; Indicators and Reagents; Todralazine | 1977 |
Collaborative study of mutagenicity with Salmonella typhimurium TA102.
Topics: Evaluation Studies as Topic; Glutaral; Glyoxal; Hydralazine; Hydrazines; Mutagenicity Tests; Mutagens; Phenylhydrazines; Salmonella typhimurium | 1992 |
Determination of hydrazine in hydralazine by capillary gas chromatography with nitrogen-selective detection after benzaldehyde derivatization.
Topics: Benzaldehydes; Chemical Phenomena; Chemistry; Chromatography, Gas; Hydralazine; Hydrazines; Indicators and Reagents; Solutions | 1990 |
Biochemical changes in cultured murine fibroblasts after treatment with hydrazinophthalazines.
Topics: Animals; Cell Division; Cells, Cultured; DNA; Fibroblasts; Hydralazine; Hydrazines; Liver; Mice; Proteins; Todralazine | 1989 |
Influence of long-term treatment with hydrazinophthalazines on the activity of lysosomal exoglycosidases in rat tissues.
Topics: Animals; Antibodies, Anti-Idiotypic; Disease Models, Animal; Glycoside Hydrolases; Hydralazine; Hydrazines; Lupus Erythematosus, Systemic; Lysosomes; Male; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values; Todralazine | 1988 |
Preferential renal vasodilator effects of CGP 22979A in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Hindlimb; Hydralazine; Hydrazines; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Vascular Resistance; Vasodilator Agents | 1985 |
Plasma hydrazine concentrations in man after isoniazid and hydralazine administration.
Topics: Acetylation; Adult; Gas Chromatography-Mass Spectrometry; Humans; Hydralazine; Hydrazines; Hypertension; Isoniazid; Male; Phenotype | 1985 |
Genetic toxicity of several antihypertensive drugs possessing a hydrazine group.
Topics: Animals; Antihypertensive Agents; Benserazide; Carbidopa; Hydralazine; Hydrazines; Male; Mutagens; Rats; Rats, Inbred ACI | 1985 |
Occupational dermatitis from hydrazine hydrate used in boiler protection. Cross sensitization to apresoline, isoniazid and phenelzine.
Topics: Adult; Dermatitis, Contact; Dermatitis, Occupational; Environmental Exposure; Humans; Hydralazine; Hydrazines; Isoniazid; Male; Phenelzine; Skin Tests | 1967 |
Antihypertensive activity of 1-(2-(1,3-dimethyl-2-butenylidene)-hydrazino)-phthalazine (DJ-1461), a new phthalazine derivative.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Heterocyclic Compounds; Hydralazine; Hydrazines; Hypertension; Phthalazines; Rats; Stimulation, Chemical; Time Factors | 1974 |
[Studied on 14C-labelled N1-carboethoxy-N2-hydrazinophthalazine hydrochloride (Apiracohl). I. Synthesis of labelled compound and metabolism in rats (author's transl)].
Topics: Animals; Antihypertensive Agents; Carbon Radioisotopes; Heterocyclic Compounds; Hydralazine; Hydrazines; Isotope Labeling; Male; Rats; Spectrophotometry | 1973 |
Onthe pharmacology of 3-hydrazino-6-(N,N-bis(2-hydroxyethyl)amino)-pyridazine-dihydrochloride (L 6150).
Topics: Animals; Blood Pressure; Cardiac Output; Decerebrate State; Dogs; Ethanolamines; Female; Hydralazine; Hydrazines; Hypertension; Lethal Dose 50; Male; Mice; Pyridazines; Rabbits; Rats; Spinal Cord; Time Factors | 1973 |
Species dependent toxicity of six substituted hydrazines.
Topics: Allyl Compounds; Animals; Benzoates; Benzyl Compounds; Cricetinae; Dose-Response Relationship, Drug; Hydralazine; Hydrazines; Mice; Neoplasms; Species Specificity | 1974 |
[Hydrazides and hydrazide derivatives of dicarboxylic acids. 12. Conversion of some substituted malonic acid dihydrazides with aldehydes and ketones].
Topics: Aldehydes; Bromides; Chemistry, Pharmaceutical; Chromatography, Thin Layer; Heterocyclic Compounds; Hydralazine; Hydrazines; Ketones; Malonates; Oxidation-Reduction | 1969 |
[Influence of a combinated adelphan-esidrix and clonidin therapy on blood pressure and renal function in renal hypertension].
Topics: Adult; Aniline Compounds; Blood Pressure Determination; Blood Urea Nitrogen; Drug Synergism; Female; Glomerular Filtration Rate; Humans; Hydralazine; Hydrazines; Hydrochlorothiazide; Hypertension, Renal; Imidazoles; Male; Metabolic Clearance Rate; Middle Aged; Reserpine; Time Factors | 1971 |
Chronic toxicity of carboethoxyphthalazinohydrazine and its influence on the excretion of 5-hydroxyindoleacetic acid and the activity of 5-htp-decarboxylase in white rats.
Topics: Animals; Anura; Aromatic Amino Acid Decarboxylase Inhibitors; Culture Techniques; Dopa Decarboxylase; Female; Heterocyclic Compounds; Hydralazine; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Lung; Lupus Erythematosus, Systemic; Mice; Rats; Spleen | 1968 |
The chemical induction of systemic lupus erythematosus and lupus-like illnesses.
Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythematosus, Systemic; Lupus Vulgaris; Lymphocytes; Phenotype; Procainamide; Time Factors | 1981 |
Enzymatic activation of hydrazine derivatives. A spin-trapping study.
Topics: Electron Spin Resonance Spectroscopy; Hydralazine; Hydrazines; Hydrogen-Ion Concentration; Iproniazid; Isoniazid; Phenylhydrazines | 1983 |
Ambulatory long-term vasodilator therapy for chronic refractory heart failure: hemodynamic evaluation and clinical response.
Topics: Adult; Aged; Ambulatory Care; Cardiac Catheterization; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Hydralazine; Hydrazines; Isosorbide Dinitrate; Long-Term Care; Male; Middle Aged; Mitral Valve Insufficiency; Stroke Volume; Todralazine | 1984 |
Determination of hydrazine in pharmaceuticals III: hydralazine and isoniazid using GLC.
Topics: Chemistry, Pharmaceutical; Chromatography, Gas; Drug Combinations; Drug Contamination; Drug Storage; Hydralazine; Hydrazines; Isoniazid; Solutions; Tablets | 1983 |
Hydrazine levels in formulations of hydralazine, isoniazid, and phenelzine over a 2-year period.
Topics: Drug Contamination; Drug Storage; Hydralazine; Hydrazines; Isoniazid; Phenelzine; Solutions; Tablets; Time Factors | 1983 |
Interactions between hydralazine, propildazine and purines on arterial smooth muscle.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Arteries; Hydralazine; Hydrazines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Propranolol; Purines; Pyridazines; Rats; Theophylline | 1981 |
[Phthalazine derivatives in the treatment of arterial hypertension].
Topics: Arterioles; Blood Pressure; Humans; Hydralazine; Hydrazines; Hypertension; Todralazine; Vasodilator Agents | 1981 |
Potentiation of cardiovascular responses to hydralazine by diverse hydrazine derivatives.
Topics: Animals; Blood Pressure; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Heart Rate; Hydralazine; Hydrazines; Male; Rats; Rats, Wistar | 1994 |
Hydralazine and other hydrazine derivatives and the formation of DNA adducts.
Topics: Alkylation; Animals; Chromatography, High Pressure Liquid; DNA; Dose-Response Relationship, Drug; Formaldehyde; Guanine; Hydralazine; Hydrazines; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley | 1994 |
Hydrazine-mediated DNA damage: role of hemoprotein, electron transport, and organic free radicals.
Topics: DNA Damage; DNA, Superhelical; Electron Transport; Erythrocytes; Free Radicals; Hemoglobins; Humans; Hydralazine; Hydrazines; Monomethylhydrazine; Phenelzine; Phenylhydrazines | 1994 |
Evaluation of mutagenicity testing with Salmonella typhimurium TA102 in three different laboratories.
Topics: Formaldehyde; Glutaral; Glyoxal; Hydralazine; Hydrazines; Laboratories; Mutagenicity Tests; Phenylhydrazines; Reproducibility of Results; Salmonella typhimurium | 1993 |
Pyridazine derivatives. XI: Antihypertensive activity of 3-hydrazinocycloheptyl[1,2-c]pyridazine and its hydrazone derivatives.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium; Calcium Radioisotopes; Female; Hydralazine; Hydrazines; Hydrazones; In Vitro Techniques; Isotonic Solutions; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Pyridazines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 1993 |
Effects of hydrazine, phenelzine, and hydralazine treatment on rat hepatic and renal drug-metabolizing enzyme expression.
Topics: Animals; Blotting, Northern; Cytochrome P-450 CYP2E1; Glutathione Transferase; Hydralazine; Hydrazines; Kidney; Liver; Male; Phenelzine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclic GMP; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydralazine; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Male; Methacrylates; Natriuresis; Nitrates; Nitrites; Nitroprusside; Rats; Rats, Inbred Dahl; Renal Artery; Thromboxane A2; Vasoconstriction | 2001 |
Effects of hydrazine derivatives on vascular smooth muscle contractility, blood pressure and cGMP production in rats: comparison with hydralazine.
Topics: Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Hydralazine; Hydrazines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Wistar | 2003 |
[Comparison of the amine oxidase-inhibiting and hypotensive effects of hydrazinophthalazines].
Topics: Amine Oxidase (Copper-Containing); Amines; Hydralazine; Hydrazines; Monoamine Oxidase Inhibitors; Oxidoreductases; Sympatholytics | 1955 |
[Effect of hydrazinophthalazine on renal circulation in arterial hypertension].
Topics: Hydralazine; Hydrazines; Hypertension; Kidney; Renal Circulation | 1956 |
[Modern medications of arterial hypertension. III. Treatment with derivatives of hydrazine].
Topics: Humans; Hydralazine; Hydrazines; Hypertension; Monitoring, Physiologic; Sympatholytics | 1957 |
Hydralazine syndrome; hypersensitivity or toxicity? its significance in understanding of collagen disease.
Topics: Arthritis; Arthritis, Rheumatoid; Collagen Diseases; Humans; Hydralazine; Hydrazines | 1957 |
[Hydralazine in the treatment of intermittent claudication].
Topics: Humans; Hydralazine; Hydrazines; Intermittent Claudication | 1957 |
[Hypotensive effect of combined treatment with esidres and serpasil-apresoline].
Topics: Chlorothiazide; Combined Modality Therapy; Hydralazine; Hydrazines; Hypotension; Manipulation, Osteopathic; Reserpine | 1961 |
[Hydralazine syndrome after prolonged treatment with adelphan].
Topics: Hydralazine; Hydrazines; Hypertension; Lupus Erythematosus, Systemic; Reserpine | 1961 |
[On the treatment of pre-eclampsia with Esidrex and Adelphan-Esidrex].
Topics: Chlorothiazide; Drug Combinations; Female; Hydralazine; Hydrazines; Hydrochlorothiazide; Pre-Eclampsia; Pregnancy; Reserpine | 1961 |
Physiological disposition of hydralazine (1-hydrazinophthalazine) and a method for its determination in biological fluids.
Topics: Body Fluids; Feces; Humans; Hydralazine; Hydrazines; Personality | 1961 |
[Collagenosis after hydrazine administration in the rat].
Topics: Animals; Collagen Diseases; Hydralazine; Hydrazines; Rats | 1960 |
Contact dermatitis from hydrazine hydrochloride in soldering flux; cross sensitization to apresoline and isoniazid.
Topics: Dermatitis, Contact; Humans; Hydralazine; Hydrazines; Isoniazid; Salts; Zinc Compounds | 1959 |
[Contact dermatitis caused by industrial use of hydrazine derivatives with group hypersensitivity to hydralazine (Apresoline) and isoniazid (INH)].
Topics: Dermatitis, Contact; Dermatitis, Occupational; Humans; Hydralazine; Hydrazines; Hypersensitivity; Isoniazid | 1962 |
Renal function and systemic blood pressure changes following the administration of hydrazinophthalazine.
Topics: Blood Pressure; Chemical and Drug Induced Liver Injury; Humans; Hydralazine; Hydrazines; Liver; Pharmaceutical Preparations | 1950 |
Some pharmacodynamic effects of 1-hydrazinophthalazine (C-5968) with particular reference to renal function and cardiovascular response.
Topics: Cardiovascular System; Humans; Hydralazine; Hydrazines; Kidney | 1951 |
Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde scavengers.
Topics: Aldehydes; Animals; Atherosclerosis; Cells, Cultured; DNA; Hydralazine; Hydrazines; Lipoproteins, LDL; Male; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Rabbits; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction | 2006 |
Inhibition of semicarbazide-sensitive amine oxidase attenuates myocardial ischemia-reperfusion injury in an in vivo rat model.
Topics: Amine Oxidase (Copper-Containing); Animals; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Heart Rate; Hydralazine; Hydrazines; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Semicarbazides | 2011 |